CN104547084A - Medicinal liquor for treating rheumatic arthritis and relaxing tendons and activating collaterals and preparation method thereof - Google Patents

Medicinal liquor for treating rheumatic arthritis and relaxing tendons and activating collaterals and preparation method thereof Download PDF

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CN104547084A
CN104547084A CN201510003865.8A CN201510003865A CN104547084A CN 104547084 A CN104547084 A CN 104547084A CN 201510003865 A CN201510003865 A CN 201510003865A CN 104547084 A CN104547084 A CN 104547084A
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parts
radix
blood
rheumatic arthritis
tendons
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许福亮
王云海
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Abstract

The invention discloses medicinal liquor for treating rheumatic arthritis and relaxing tendons and activating collaterals and a preparation method thereof. The medicinal liquor is prepared from the following main raw medicines in parts by weight: 10 to 20 parts of notopterygium root, 9 to 18 parts of corydalis tuber, 9 to 18 parts of connaraceae, 8 to 16 parts of luffa stem, 8 to 16 parts of radix angelicae pubescentis, 9 to 12 parts of aster tagasagomontanus sasaki, 15 to 30 parts of radix puerariae, 12 to 20 parts of ligusticum wallichii, 9 to 12 parts of laciniate begonia herb, 9 to 16 parts of selaginella tamariscina, 8 to 16 parts of euonymus bungeanus, 10 to 20 parts of salvia miltiorrhiza, and 9 to 15 parts of radix aconiti agrestis. The medicinal liquor for treating rheumatic arthritis and relaxing tendons and activating collaterals is low in treatment cost, free of side effect, free of wound, obvious in treatment effect, and less in relapse possibility.

Description

Rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine and preparation method
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine and preparation method.
Background technology
Modern word belonging to rheumatic arthritis, one of main manifestations referring to rheumatic fever, the allergic disease relevant with hemolytic streptococcal infection.Typical performance is slight or moderate heating, migratory polyarthritis, affected joints mostly is the large joint such as knee joint, ankle, shoulder, elbow, wrist, is commonly transferred to another joint by a joint; pathological changes local presents red, swollen, scorching hot, severe pain, and some patients also has several joint to fall ill simultaneously.Atypical patient only has arthralgia and shows without other inflammation, and acute inflammation generally disappeared in 2 ~ 4 weeks, did not stay sequela, but normal recurrent exerbation.If active rheumatism affects heart, then can there is myocarditis, even leave over valve disorder.Rheumatism is a kind of based on the systemic disease of the non-infectious inflammation of joint and periarticular tissue by its ill reason of viewpoint of doctor trained in Western medicine, a lot of scholar thinks relevant with inherited genetic factors, autoimmune response, in a word at present doctor trained in Western medicine to etiology and pathology to the greatest extent not yet clear and definite.
The traditional Chinese medical science thinks that the reason of pathogenic factor and pathogenic process has four kinds substantially: 1, internal organs negative and positive internal injury: say by the viewpoint of traditional Chinese medical science yin-yang and five elements, and the five internal organs are the heart, liver, spleen, lung, kidney.Heart governing blood and vessels: liver governing tendons; Spleen governing muscles; Lung governing skin and hair; Kidney governing bones.Rheumatism mainly liver spleen kidney generation internal injury occurs, and the kidney being the origin of congenital constitution.The raw marrow of store essential substances is bone at body is the viscus with functions of reproduction and development; Liver is muscle basis, the raw muscle of store blood, system department muscles and bones joint; The spleen being the foundation of acquired constitution, the source of QI and blood biochemistry, main limb muscle.The Yinyang of human body must keep balance, if negative and positive are uneven, occurs that inclined Sheng declines partially, is subject to pathogen and invades, so there is rheumatismal heat and cold Symptoms.2, the heresy of diseases caused by exogenous pathogenic factor six climate exopathogens: the pathogen of six climate exopathogens refers to that wind, cold, administration, wet, dry, that fire six kinds is normal gas six gas cuts too enter the person and cause the gas of morbidity to be just called pathogen, and rheumatism is subject to wind, cold, wet pathogen and invades personal and occur.Migratory BI-syndrome caused mainly by pathogenic wind; Cold survivor is arthralgia aggravated by cold; Dampness victor is damp arthralgia.Wind-cold damp pathogen impatency meridians and joint, stagnation of QI and blood may bring about pain, so cause joint swelling and pain.3, raw in phlegm-turbidity and blood stasis blood: namely expectorant is turbid is the pathological product of human body under pathogenic factor effect with blood stasis, also human body can be acted on as the cause of disease, rheumatism has mostly chronicly carries out process, disease for a long time, then pathogenic factor going from the exterior into the interior, by gently weighing, causes visceral dysfunction, and the result of visceral dysfunction just produces the turbid and blood stasis of expectorant, these are exactly the touching and basic reason of refractory of the rheumatism state of an illness.4, ying-qi defends blood imbalance: the traditional Chinese medical science says that ying-qi defends blood, and in ying-qi arteries and veins, defensive QI circulating outside the vessel, negative and positive are passed through mutually, and controlled atmosphere blood is smooth.Nutrition extremity bones of the body collectively zang-fu differentiation.Battalion defends and adjusts, and defends the body surface that gas protects people outside, and defence pathogen invades health, disharmony of nutrient QI with defensive QI, and pathogen is taken advantage of a weak point, and it is one of key factor of rheumatism morbidity that Gu Ying defends imbalance.5, Nervous and Mental Factors: to feel exhausted, direct stimulation, wound and the worry etc. that causes thereof, all belongs to the pathogenic factors of rheumatoid arthritis.Everyone does not allow oneself own overworked for we, also has and keeps actively optimistic phychology.6, environmental factors: the some people had occupies cold for a long time, wet environment causes joint to make moist, cold injury etc., is also the pathogenic factors of rheumatoid arthritis.7, infective agent: as rheumatoid arthritis feelings all can be brought out or increase the weight of to sinusitis, pharyngitis, tonsillitis, cholecystitis, otitis media, adnexitis, appendicitis, periodontitis and upper respiratory tract infection, influenza, parotitis, tuberculosis, hepatitis etc., so above symptom also all belongs to the pathogenic factors of rheumatoid arthritis.Patient occurs that above disease must hospital treatment in time, in order to avoid increase the weight of the state of an illness.Due to rheumatic arthritis involve be the musculoskeletal system of human body as joint, muscle, ligament, tendon, synovial bursa etc., bring great inconvenience to patient.
Application publication number CN 103845612 A(application number 201210510176.2) Chinese patent literature disclose one and treat rheumatic arthritis medicated wine, featherleaf rodgersflower 10 ~ 15 grams, Herba Lysionoti Pauciflori 20 ~ 25 grams, 10 ~ 15 grams, Fructus Piperis, Herba pteridis vittatae 40 ~ 45 grams, Quartz Album 40 ~ 45 grams, thousand short 30 ~ 35 grams.Application publication number CN 103690893 A(application number 201310715632.1) Chinese patent literature disclose a kind of medicated wine for the treatment of rheumatic arthritis, it is characterized in that: be made up of following raw material of Chinese medicine, raw material of Chinese medicine is by following parts by weight: Fructus Lycii 25-35 gram, Rhizoma Polygonati 25-35 gram, Rhizoma Atractylodis Macrocephalae 25-35 gram, Radix Aconiti Preparata 25-35 gram, RADIX ACONITILATERALIS PREPARATA 25-35 gram, Rhizoma Et Radix Notopterygii 15-20 gram, Radix Angelicae Pubescentis 15-20 gram, Radix Clematidis 15-20 gram, Radix Angelicae Sinensis 15-20 gram, Rhizoma Curcumae Longae 15-20 gram, Scolopendra 15-20 gram, Zaocys 85-95 gram, Rhizoma Homalomenae 50-60 gram.Application publication number CN 104127559 A(application number 201410321170.X) Chinese patent literature disclose a kind of medicated wine for the treatment of rheumatic arthritis, this medicated wine is used for oral, is made up of: Radix Angelicae Sinensis 15g, Flos Carthami 15g, Radix Rehmanniae Preparata 10g, Fructus Aurantii 15g, Ramulus Cinnamomi 10g, Caulis Sinomenii 10g, Radix Cyathulae 10g, Rhizoma Cimicifugae 10g, Cortex Cinnamomi 10g, Radix Notoginseng 6g, Eupolyphaga Seu Steleophaga 10g, Radix Astragali 10g, Cortex Eucommiae 10g, eight stupefied numb 15g, Cortex Acanthopancis 15g, Radix Dipsaci 10g, Olibanum 6g, Myrrha 6g, Radix Glycyrrhizae 6g the raw material of following weight g; Above-mentioned raw material of Chinese medicine is cleaned and dries, join in 60 degree of rice wine of 2500g, under room temperature, soak 7-10 days.
Rheumatoid arthritis patients usually torment by arthralgia, and, also because arthralgia makes quality of life decline.Doctor trained in Western medicine mainly adopts analgesia anti-inflammation medicine, amcinonide etc. to control symptom, stablizes the state of an illness, but the most side effect of medicine used is serious, and many patients are inspired awe even from distance.Up to now, the process that a kind of specific medicament can prevent or the articulation structure that significantly slows down destroys is not found.And operative treatment, the features such as because indication requires very strict, the crowd being applicable to clinically performing an operation less than 5%, and exists costly, and wound is large, and convalescent period is long, easy recurrence, so cannot popularize the Therapeutic Method of this rheumatic arthritis in an all-round way at all.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine and preparation method.Rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine treatment cost provided by the invention is low, have no side effect, hurtless measure, evident in efficacy, not easily recur.
Technical scheme of the present invention is:
Rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine, takes off the primary raw material medicine stating weight proportion and is prepared from: Rhizoma Et Radix Notopterygii 10-20, Rhizoma Corydalis 9-18, cattle rattan 9-18, Ramulus Luffae 8-16, Radix Angelicae Pubescentis 8-16, RADIX ET RHIZOMA LIGULARIAE 9-12, Radix Puerariae 15-30, Rhizoma Chuanxiong 12-20, Herba Begoniae Laciniatae 9-12, Herba Selaginellae Davidii 9-16, Herba Euonymi Bungeani 8-16, Radix Salviae Miltiorrhizae 10-20, Radix Aconiti Sungpanensis 9-15.
Rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Rhizoma Et Radix Notopterygii 13-16, Rhizoma Corydalis 12-16, cattle rattan 11-15, Ramulus Luffae 10-14, Radix Angelicae Pubescentis 9-13, RADIX ET RHIZOMA LIGULARIAE 9.5-11, Radix Puerariae 20-27, Rhizoma Chuanxiong 14-18, Herba Begoniae Laciniatae 10-11.5, Herba Selaginellae Davidii 12-15, Herba Euonymi Bungeani 10-14, Radix Salviae Miltiorrhizae 13-17, Radix Aconiti Sungpanensis 11-13.
Rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: Rhizoma Et Radix Notopterygii 14, Rhizoma Corydalis 14, cattle rattan 13, Ramulus Luffae 12, Radix Angelicae Pubescentis 11, RADIX ET RHIZOMA LIGULARIAE 10, Radix Puerariae 24, Rhizoma Chuanxiong 16, Herba Begoniae Laciniatae 10.5, Herba Selaginellae Davidii 13.5, Herba Euonymi Bungeani 12, Radix Salviae Miltiorrhizae 15, Radix Aconiti Sungpanensis 12.
The preparation method of above-mentioned rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine is:
(1) get Herba Begoniae Laciniatae, mix thoroughly with saline, every 100kg Herba Begoniae Laciniatae uses Sal 2.1-2.8kg, and moistening, to thoroughly, is put in hot pot, and by slow fire heating, fried dry, taking-up cools, and is ground into fine powder;
(2) all the other except Herba Begoniae Laciniatae 12 taste medical material is ground into end, dry at the temperature of 50-70 DEG C, dry 2.5-4.5 hour;
(3) by step (1) and the mixing of step (2) gained, enter cloth bag, put in tank, add Chinese liquor, the amount of Chinese liquor is 7-12 times of 13 taste Chinese crude drug gross weights, and the number of degrees of Chinese liquor are 50-68 degree, is placed on the sealing of sombre lucifuge place and soaks, every day stirs once, soak 18-28 days, filter medicinal residues, wine liquid leaves standstill 8-15 hour, filter, the wine liquid after filtration is stored in bottle.
Preferably be that, in step (1), every 100kg Herba Begoniae Laciniatae uses Sal 2.3-2.6kg.
Preferably be in step (2), dry at the temperature of 55-65 DEG C.
Preferably be in step (2), dry 3-4.2 hour.
Preferably be in step (3), the amount of Chinese liquor is 8-11 times of 13 taste Chinese crude drug gross weights.
Preferably be in step (3), the number of degrees of Chinese liquor are 52-56 degree.
Preferably be in step (3), soak 20-26 days.
Preferably be in step (3), the quiet 10-13 hour of wine liquid.
Be more preferably, in step (1), every 100kg Herba Begoniae Laciniatae uses Sal 2.4kg.
Be more preferably, in step (2), dry at the temperature of 60 DEG C.
Be more preferably, in step (2), dry 3.6 hours.
Be more preferably, in step (3), the amount of Chinese liquor is 10 times of 13 taste Chinese crude drug gross weights.
Be more preferably, in step (3), the number of degrees of Chinese liquor are 53 degree.
Be more preferably, in step (3), soak 24 days.
Be more preferably, in step (3), wine liquid leaves standstill 12 hours.
Rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine preparation provided by the invention is convenient.In addition, excellent results of the present invention also shows:
1, formed by the meticulous compatibility of the pure Chinese herbal medicine of multi-flavor, absorb rapidly, thus realize the effects such as expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, numbness relieving and pain relieving, dissipating blood stasis for subsidence of swelling, reach the object of curing rheumatic arthritis;
2, treatment cost is low, alleviates the financial burden of patient;
3, evident in efficacy, hurtless measure, have no side effect, alleviate the misery of patient;
4, treating both the principal and the secondary aspects of a disease at the same time, not easily recurs;
5, the property of medicine is stablized, safe and effective.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Rhizoma Et Radix Notopterygii: base is former: be dry rhizome and the root of samphire Rhizoma Et Radix Notopterygii or Radix et Rhizoma Notopterygii.The property of medicine: pungent, bitter, temperature.Return bladder, kidney channel.Function cures mainly: cold expelling, dispels the wind, dehumidifying, pain relieving.For anemofrigid cold headache, rheumatic arthralgia, aching pain in should and back.
Rhizoma Corydalis: base is former: be the tuber of papaveraceae plant corydalis.The property of medicine: pungent, bitter, temperature.Return liver, stomach warp.Function cures mainly: invigorate blood circulation, and dissipating blood stasis is regulated the flow of vital energy, pain relieving.Control all pains of trusted subordinate's waist knee joint, menoxenia, lump in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury.
Niu Teng: base is former: be stem and the root of that rattan of Lardizabalaceae Caulis et folium stauntoniae platymiscium or that rattan of leaf tail.The property of medicine: bitter, cool.Function cures mainly: dispel the wind dissipating blood stasis, pain relieving, inducing diuresis to remove edema.Cure mainly rheumatic arthralgia, traumatic pain, various neuropathic pain, dysuria, edema.
Ramulus Luffae: base is former: be the stem of cucurbitaceous plant Fructus Luffae or Guangdong Fructus Luffae.Chemical analysis: Ramulus Luffae is containing Saponin.The property of medicine: " book on Chinese herbal medicine asks former ": " bitter, be slightly cold, mild toxicity." return through " book on Chinese herbal medicine is new again ": " enter the heart, spleen, kidney three warp." function cures mainly: relaxing muscles and tendons, invigorate blood circulation, spleen invigorating, parasite killing.Control waist knee joint numb limbs and tense tendons, menoxenia, edema, tooth reveals, nasal sinusitis, gingival atrophy.
Radix Angelicae Pubescentis: base is former: be the dry root of samphire Angelica pubescens.Chemical composition: have bitter scholar's Coumarins compound in root, columbianetin and caproate thereof, osthole, different imperatorin, bergapten, xanthotoxin, columbianadin, columbianetin glycoside, Angelica pubescens alcohol, angelol D, G, B.Also containing γ-aminobutyric acid and volatile oil.The property of medicine: pungent, bitter, tepor.Return kidney, urinary bladder channel.Function cures mainly: expelling wind and removing dampness, numbness relieving and pain relieving.For anemofrigid-damp arthralgia, lumbocrural pain, few cloudy volt wind headache.
RADIX ET RHIZOMA LIGULARIAE: base is former: be the root and rhizome of feverfew ligularia fischeri.The property of medicine: pungent, tepor.Function cures mainly: eliminate the phlegm, cough-relieving, vital energy regualting and blood circulation-promoting, pain relieving.Main cough, general many asthma, pertussis, lumbago and skelalgia, impairment caused by overstrain, traumatic injury.
Radix Puerariae: base is former: be the dry root of legume pueraria lobata.Practise and claim Herba Gelsemii Elegantis.Dry.The property of medicine: sweet, pungent, cool.Return spleen, stomach warp.Function cures mainly: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.For fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels, hypertension neck pain.
Rhizoma Chuanxiong: base is former: be the dry rhizome of samphire Rhizoma Chuanxiong.The property of medicine: pungent, temperature.Return liver, gallbladder, pericardium channel.Function cures mainly: blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia, amenorrhea dysmenorrhea ， mass in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Herba Begoniae Laciniatae: base is former: be the herb of Begoniaceae plant Begonia pedatifida.The property of medicine: sweet, sour, cold.Function cures mainly: heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling.Main cough due to lung-heat, furuncle carbuncle, dysmenorrhea, amenorrhea, beriberoid pyretic arthralgia, treating swelling and pain by traumatic injury, Serpentis flood dragon hinders.
Herba Selaginellae Davidii: base is former: for Spikemoss plant is overgrow the herb of Herba Selaginellae.The property of medicine: bitter, micro-pungent, is slightly cold.Function cures mainly: clearing away heat-damp and promoting diuresis, relaxing muscles and tendons and activating QI and blood in the collateral.Cure mainly hepatitis, diarrhoea, rheumatic arthritis, scald, traumatic hemorrhage.
Herba Euonymi Bungeani: base is former: be root, the bark of Celastraceae vegetable silk Populus deltoides.The property of medicine: bitter, pungent, cool.Return liver,spleen,kidney warp.Function cures mainly: expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, removing toxic substances hemostasis.Main air wet arthritis, lumbago, traumatic injury wound is swollen, thromboangiitis obliterans, lung abscess, epistaxis, furuncle toxic swelling.
Radix Salviae Miltiorrhizae: base is former: be the dry root and rhizome of labiate Radix Salviae Miltiorrhizae.The property of medicine: bitter, is slightly cold.GUIXIN, Liver Channel.Function cures mainly: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, and clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea ， lumps in the chest and abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Radix Aconiti Sungpanensis: base is former: be the root of Ranunculaceae aconitum plant Aconitum Sungpanense Hand-mazz.Composition: talaisamine, chasmanine, vilmorrianine A.Pharmacology: antiinflammatory, refrigeration function.The property of medicine: pungent, bitter, heat, greatly poison.Return Liver Channel.Function cures mainly: expelling wind and dampness, dispersing cold for relieving pain, dissipating blood stasis for subsidence of swelling.Cure mainly anemofrigid-damp arthralgia, arthrodynia of extremities, toothache, traumatic injury, carbuncle skin infection, neuralgia.
embodiment 1rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine, the primary raw material medicine getting following weight parts is prepared from (every part is 55g): Rhizoma Et Radix Notopterygii 10 parts, Rhizoma Corydalis 9 parts, 9 parts, cattle rattan, Ramulus Luffae 8 parts, Radix Angelicae Pubescentis 8 parts, RADIX ET RHIZOMA LIGULARIAE 9 parts, Radix Puerariae 15 parts, Rhizoma Chuanxiong 12 parts, Herba Begoniae Laciniatae 9 parts, Herba Selaginellae Davidii 9 parts, Herba Euonymi Bungeani 8 parts, Radix Salviae Miltiorrhizae 10 parts, Radix Aconiti Sungpanensis 9 parts.
The preparation method of above-mentioned rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine is:
(1) get Herba Begoniae Laciniatae, mix thoroughly with saline, every 100kg Herba Begoniae Laciniatae uses Sal 2.1kg, and moistening, to thoroughly, is put in hot pot, and by slow fire heating, fried dry, taking-up cools, and is ground into fine powder;
(2) all the other except Herba Begoniae Laciniatae 12 taste medical material is ground into end, dry at the temperature of 50 DEG C, dry 2.5 hours;
(3) by step (1) and the mixing of step (2) gained, enter cloth bag, put in tank, add Chinese liquor, the amount of Chinese liquor is 7 times of 13 taste Chinese crude drug gross weights, and the number of degrees of Chinese liquor are 50 degree, is placed on the sealing of sombre lucifuge place and soaks, every day stirs once, soak 18 days, filter medicinal residues, wine liquid leaves standstill 8 hours, filter, the wine liquid after filtration is stored in bottle.
The using method of rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine of the present invention: for oral administration, every day twice, each 30-50 milliliter; Also can external, dip medicinal liquid with rayon balls and embrocate affected part, every day embrocates 3-5 time.
embodiment 2rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine, the primary raw material medicine getting following weight parts is prepared from (every part is 55g): Rhizoma Et Radix Notopterygii 20 parts, Rhizoma Corydalis 18 parts, 18 parts, cattle rattan, Ramulus Luffae 16 parts, Radix Angelicae Pubescentis 16 parts, RADIX ET RHIZOMA LIGULARIAE 12 parts, Radix Puerariae 30 parts, Rhizoma Chuanxiong 20 parts, Herba Begoniae Laciniatae 12 parts, Herba Selaginellae Davidii 16 parts, Herba Euonymi Bungeani 16 parts, Radix Salviae Miltiorrhizae 20 parts, Radix Aconiti Sungpanensis 15 parts.
The preparation method of above-mentioned rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine is:
(1) get Herba Begoniae Laciniatae, mix thoroughly with saline, every 100kg Herba Begoniae Laciniatae uses Sal 2.8kg, and moistening, to thoroughly, is put in hot pot, and by slow fire heating, fried dry, taking-up cools, and is ground into fine powder;
(2) all the other except Herba Begoniae Laciniatae 12 taste medical material is ground into end, dry at the temperature of 70 DEG C, dry 4.5 hours;
(3) by step (1) and the mixing of step (2) gained, enter cloth bag, put in tank, add Chinese liquor, the amount of Chinese liquor is 12 times of 13 taste Chinese crude drug gross weights, and the number of degrees of Chinese liquor are 68 degree, is placed on the sealing of sombre lucifuge place and soaks, every day stirs once, soak 28 days, filter medicinal residues, wine liquid leaves standstill 15 hours, filter, the wine liquid after filtration is stored in bottle.
model case one: Liu XX, female, 36 years old.Private prosecution postpartum rheumatic 7 years.Symptom: fear of cold aversion to wind is afraid of cold, summer cotton dress, going out can not be by bike, overall pain, headache, mandibular joint pain, wrist pain, finger ache, have a pain in the leg, lean body mass, the hardening atrophy of whole body many places muscle, back muscles spasm is stiff cannot sleep on one's back, and insomnia and dreamful sleep, mood agitation, hypomnesis, appetite are poor.Take the present embodiment gained rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine, every day twice, each 30 milliliters.After 5 days, General Symptoms has alleviation, and sensation health is than light in the past, and sleep quality obviously improves, and constipation phenomenon is alleviated.After 10 days, private prosecution appetite improves, and has hunger sensation.After 20 days, patient's private prosecution remission is felt quite pleased, and just the physiological function such as excretion is normally coordinated for sleep, appetite, two, overall pain symptom SPR.After 30 days, patient's sensory symptoms disappears completely, does not recur so far.
embodiment 3rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine, the primary raw material medicine getting following weight parts is prepared from (every part is 55g): Rhizoma Et Radix Notopterygii 13 parts, Rhizoma Corydalis 12 parts, 11 parts, cattle rattan, Ramulus Luffae 10 parts, Radix Angelicae Pubescentis 9 parts, RADIX ET RHIZOMA LIGULARIAE 9.5 parts, Radix Puerariae 20 parts, Rhizoma Chuanxiong 14 parts, Herba Begoniae Laciniatae 10 parts, Herba Selaginellae Davidii 12 parts, Herba Euonymi Bungeani 10 parts, Radix Salviae Miltiorrhizae 13 parts, Radix Aconiti Sungpanensis 11 parts.
The preparation method of above-mentioned rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine is:
(1) get Herba Begoniae Laciniatae, mix thoroughly with saline, every 100kg Herba Begoniae Laciniatae uses Sal 2.3kg, and moistening, to thoroughly, is put in hot pot, and by slow fire heating, fried dry, taking-up cools, and is ground into fine powder;
(2) all the other except Herba Begoniae Laciniatae 12 taste medical material is ground into end, dry at the temperature of 55 DEG C, dry 3 hours;
(3) by step (1) and the mixing of step (2) gained, enter cloth bag, put in tank, add Chinese liquor, the amount of Chinese liquor is 8 times of 13 taste Chinese crude drug gross weights, and the number of degrees of Chinese liquor are 52 degree, is placed on the sealing of sombre lucifuge place and soaks, every day stirs once, soak 20 days, filter medicinal residues, wine liquid leaves standstill 10 hours, filter, the wine liquid after filtration is stored in bottle.
model case two:summer XX, man, 63 years old.Medical history: suffer from waist leg joint pain more than ten years, localized pain, pain increase in intensity under coldness.Start right knee joint heavier, left lower limb and lumbago are slightly light.Before 1 year, cold type of pain is heavy more, lower limb activities adverse, so that can not Go to ground activity.Local hospital is diagnosed as rheumatic arthritis.Treat, have no improvement.Then come to go to a doctor.Examine and see: be lower cold extremities, osteodynia, numbness, contracture, heavy, more so, yellowish complexion is dark black for right lower limb, and the micro-crow of body of the tongue, thin fur is greyish white, deep-thready pulse.Stretch moving difficulty in the wrong, or must assist in and can move one's steps by crutch.Take the present embodiment gained rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine, every day twice, each 50 milliliters.Take 1 month, pain symptom is obviously alleviated.Continue to take 1 month, transference cure, freedom of movement, do not recur so far.
embodiment 4rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine, the primary raw material medicine getting following weight parts is prepared from (every part is 55g): Rhizoma Et Radix Notopterygii 16 parts, Rhizoma Corydalis 16 parts, 15 parts, cattle rattan, Ramulus Luffae 14 parts, Radix Angelicae Pubescentis 13 parts, RADIX ET RHIZOMA LIGULARIAE 11 parts, Radix Puerariae 27 parts, Rhizoma Chuanxiong 18 parts, Herba Begoniae Laciniatae 11.5 parts, Herba Selaginellae Davidii 15 parts, Herba Euonymi Bungeani 14 parts, Radix Salviae Miltiorrhizae 17 parts, Radix Aconiti Sungpanensis 13 parts.
The preparation method of above-mentioned rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine is:
(1) get Herba Begoniae Laciniatae, mix thoroughly with saline, every 100kg Herba Begoniae Laciniatae uses Sal 2.6kg, and moistening, to thoroughly, is put in hot pot, and by slow fire heating, fried dry, taking-up cools, and is ground into fine powder;
(2) all the other except Herba Begoniae Laciniatae 12 taste medical material is ground into end, dry at the temperature of 65 DEG C, dry 4.2 hours;
(3) by step (1) and the mixing of step (2) gained, enter cloth bag, put in tank, add Chinese liquor, the amount of Chinese liquor is 11 times of 13 taste Chinese crude drug gross weights, and the number of degrees of Chinese liquor are 56 degree, is placed on the sealing of sombre lucifuge place and soaks, every day stirs once, soak 26 days, filter medicinal residues, wine liquid leaves standstill 13 hours, filter, the wine liquid after filtration is stored in bottle.
model case three:high XX, man, 28 years old.Main suit: lumbar vertebra, the gonalgia more than 1 year, companion's two-arm is stretched and is lifted difficulty, not red pneumonedema.Patient went on a long journey sweating in korneforos bathing before 2 years, later cold and cool whenever, sent out, and lower water more very, is diagnosed as rheumatic arthritis at local hospital.Drug administration is treated, all invalid.Then come to go to a doctor.Examine and see: body of the tongue has purple ecchymosis, tongue is greasy in vain, deep-slow pulse and puckery.Use the present embodiment gained rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine, dip medicinal liquid with rayon balls and embrocate affected part, embrocate 5 every day.Use two weeks, pain symptom alleviates.After one month, the heavy pain of waist knee joint all heals, and lifts arm freely.Follow up a case by regular visits to and have no recurrence.
embodiment 5rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine, the primary raw material medicine getting following weight parts is prepared from (every part is 55g): Rhizoma Et Radix Notopterygii 14 parts, Rhizoma Corydalis 14 parts, 13 parts, cattle rattan, Ramulus Luffae 12 parts, Radix Angelicae Pubescentis 11 parts, RADIX ET RHIZOMA LIGULARIAE 10 parts, Radix Puerariae 24 parts, Rhizoma Chuanxiong 16 parts, Herba Begoniae Laciniatae 10.5 parts, Herba Selaginellae Davidii 13.5 parts, Herba Euonymi Bungeani 12 parts, Radix Salviae Miltiorrhizae 15 parts, Radix Aconiti Sungpanensis 12 parts.
The preparation method of above-mentioned rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine is:
(1) get Herba Begoniae Laciniatae, mix thoroughly with saline, every 100kg Herba Begoniae Laciniatae uses Sal 2.4kg, and moistening, to thoroughly, is put in hot pot, and by slow fire heating, fried dry, taking-up cools, and is ground into fine powder;
(2) all the other except Herba Begoniae Laciniatae 12 taste medical material is ground into end, dry at the temperature of 60 DEG C, dry 3.6 hours;
(3) by step (1) and the mixing of step (2) gained, enter cloth bag, put in tank, add Chinese liquor, the amount of Chinese liquor is 10 times of 13 taste Chinese crude drug gross weights, and the number of degrees of Chinese liquor are 53 degree, is placed on the sealing of sombre lucifuge place and soaks, every day stirs once, soak 24 days, filter medicinal residues, wine liquid leaves standstill 12 hours, filter, the wine liquid after filtration is stored in bottle.
test example:in order to verify the drug effect of gained rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine (embodiment 5) of the present invention, We conducted contrast test.In April ,-2012 in February, 2009, screen 278 routine rheumatoid arthritis patients in 8 hospitals, wherein male 118 example, women 160 example, age 23-71 year, 46.5 years old mean age, course of disease 1-13.Be divided into two groups at random, experimental group and matched group (often organizing 139 people).Experimental group male 59 example, women 80 example, age 23-71 year, 46.5 years old mean age, course of disease 1-13.Matched group male 59 example, women 80 example, age 23-71 year, 46.5 years old mean age, course of disease 1-13.Case takes random acquisition method, according to the rheumatism diseases diagnostic standard that U.S.'s rheumatology is issued for 1987.Experimental group uses products obtained therefrom of the present invention, using method: for oral administration, every day twice, each 30-50 milliliter; Also can external, dip medicinal liquid with rayon balls and embrocate affected part, every day embrocates 3-5 time.Matched group uses the medicine (as Fengtong'an Capsule, aspirin tablet, Tab Fenbufeni, naproxen capsule etc.) of conventional therapy rheumatic arthritis.Criterion of therapeutical effect: with reference to Chinese Medical Association rheumatism meeting, tentative efficacy assessments in 1985 and national combination of Chinese and Western medicine rheumatism association curative effect determinate standard.Cure: clinical symptoms all disappears, and each joint part activity is as usual, anti-" O " and erythrocyte sedimentation rate are within normal range, and line is taken the photograph sheet prompting diseased region soft tissue inflammation swelling and disappeared; Effective: clinical symptoms obviously alleviates, each joint movement function recovers substantially, and anti-" O " and erythrocyte sedimentation rate are within normal range, and line is taken the photograph sheet prompting soft tissue inflammation swelling and disappeared; Take a turn for the better: clinical symptoms alleviates to some extent, and each joint movement function increases, anti-" O " and erythrocyte sedimentation rate decline to some extent and alleviate, and line is taken the photograph the large portion of sheet prompting soft tissue inflammation swelling and disappeared; Invalid: after treatment, the state of an illness is without improvement person.Total effectively comprising cures and effective.Treat after 30 days, result is as shown in table 1.
Table 1: gained rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine compliance test result of the present invention [example (%)]
Therapeutic effect: in 139 routine patients of experimental group, cures 96 examples, accounts for 69.06%; Effective 40 examples, account for 28.78%; Take a turn for the better 2 examples, accounts for 1.44%; Invalid 1 example, account for 0.72%, total effective rate reaches 97.84%.Successful is better than matched group.
The present invention is formed by the meticulous compatibility of the pure Chinese herbal medicine of multi-flavor.In side, Rhizoma Et Radix Notopterygii cold expelling, dispels the wind, dehumidifying, pain relieving.Rhizoma Corydalis is invigorated blood circulation, dissipating blood stasis, regulates the flow of vital energy, pain relieving.Cattle rattan is dispeled the wind dissipating blood stasis, pain relieving, inducing diuresis to remove edema.Ramulus Luffae relaxing muscles and tendons, invigorates blood circulation, spleen invigorating, parasite killing.Radix Angelicae Pubescentis expelling wind and removing dampness, numbness relieving and pain relieving.RADIX ET RHIZOMA LIGULARIAE eliminates the phlegm, cough-relieving, vital energy regualting and blood circulation-promoting, pain relieving.Radix Puerariae expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal.Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping.Herba Begoniae Laciniatae's heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling.Herba Selaginellae Davidii clearing away heat-damp and promoting diuresis, relaxing muscles and tendons and activating QI and blood in the collateral.Herba Euonymi Bungeani expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, removing toxic substances hemostasis.Radix Salviae Miltiorrhizae stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.Radix Aconiti Sungpanensis expelling wind and dampness, dispersing cold for relieving pain, dissipating blood stasis for subsidence of swelling.All medicines share, and have the effects such as expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, numbness relieving and pain relieving, dissipating blood stasis for subsidence of swelling, for treatment rheumatic arthritis Be very effective.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.

Claims (10)

1. rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine, is characterized in that, takes off the primary raw material medicine stating weight proportion and is prepared from: Rhizoma Et Radix Notopterygii 10-20, Rhizoma Corydalis 9-18, cattle rattan 9-18, Ramulus Luffae 8-16, Radix Angelicae Pubescentis 8-16, RADIX ET RHIZOMA LIGULARIAE 9-12, Radix Puerariae 15-30, Rhizoma Chuanxiong 12-20, Herba Begoniae Laciniatae 9-12, Herba Selaginellae Davidii 9-16, Herba Euonymi Bungeani 8-16, Radix Salviae Miltiorrhizae 10-20, Radix Aconiti Sungpanensis 9-15.
2. rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Rhizoma Et Radix Notopterygii 13-16, Rhizoma Corydalis 12-16, cattle rattan 11-15, Ramulus Luffae 10-14, Radix Angelicae Pubescentis 9-13, RADIX ET RHIZOMA LIGULARIAE 9.5-11, Radix Puerariae 20-27, Rhizoma Chuanxiong 14-18, Herba Begoniae Laciniatae 10-11.5, Herba Selaginellae Davidii 12-15, Herba Euonymi Bungeani 10-14, Radix Salviae Miltiorrhizae 13-17, Radix Aconiti Sungpanensis 11-13.
3. rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine as claimed in claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: Rhizoma Et Radix Notopterygii 14, Rhizoma Corydalis 14, cattle rattan 13, Ramulus Luffae 12, Radix Angelicae Pubescentis 11, RADIX ET RHIZOMA LIGULARIAE 10, Radix Puerariae 24, Rhizoma Chuanxiong 16, Herba Begoniae Laciniatae 10.5, Herba Selaginellae Davidii 13.5, Herba Euonymi Bungeani 12, Radix Salviae Miltiorrhizae 15, Radix Aconiti Sungpanensis 12.
4. the preparation method of the rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine as described in as arbitrary in claims 1 to 3, it is characterized in that, step is as follows:
(1) get Herba Begoniae Laciniatae, mix thoroughly with saline, every 100kg Herba Begoniae Laciniatae uses Sal 2.1-2.8kg, and moistening, to thoroughly, is put in hot pot, and by slow fire heating, fried dry, taking-up cools, and is ground into fine powder;
(2) all the other except Herba Begoniae Laciniatae 12 taste medical material is ground into end, dry at the temperature of 50-70 DEG C, dry 2.5-4.5 hour (preferred, dry 3-4.2 hour; Be more preferably, dry 3.6 hours);
(3) by step (1) and the mixing of step (2) gained, enter cloth bag, put in tank, add Chinese liquor, the amount of Chinese liquor is 7-12 times of 13 taste Chinese crude drug gross weights, and the number of degrees of Chinese liquor are 50-68 degree, is placed on the sealing of sombre lucifuge place and soaks, every day stirs once, soak 18-28 days, filter medicinal residues, wine liquid leaves standstill 8-15 hour, filter, the wine liquid after filtration is stored in bottle.
5. the preparation method of rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine as claimed in claim 4, is characterized in that, in step (1), every 100kg Herba Begoniae Laciniatae uses Sal 2.4kg with the preferred every 100kg Herba Begoniae Laciniatae of Sal 2.3-2.6kg().
6. the preparation method of rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine as claimed in claim 4, is characterized in that, dry at the temperature of 55-65 DEG C in step (2) (preferably dry at the temperature of 60 DEG C).
7. the preparation method of rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine as claimed in claim 4, is characterized in that, in step (3), the amount of Chinese liquor is 8-11 times (amount of preferred Chinese liquor is 10 times of 13 taste Chinese crude drug gross weights) of 13 taste Chinese crude drug gross weights.
8. the preparation method of rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine as claimed in claim 4, is characterized in that, in step (3), the number of degrees of Chinese liquor are 52-56 degree (number of degrees of preferred Chinese liquor are 53 degree).
9. the preparation method of rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine as claimed in claim 4, is characterized in that, soaks 20-26 days (preferably soaking 24 days) in step (3).
10. the preparation method of rheumatic arthritis relaxing muscles and tendons and activating QI and blood in the collateral medicated wine as claimed in claim 4, is characterized in that, in step (3) the quiet 10-13 of wine liquid hour (preferred wine liquid leaves standstill 12 hours).
CN201510003865.8A 2015-01-06 2015-01-06 Medicinal liquor for treating rheumatic arthritis and relaxing tendons and activating collaterals and preparation method thereof Pending CN104547084A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105582204A (en) * 2015-09-09 2016-05-18 张苗 Traditional Chinese medicine for treating Still disease

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Title
经方之精: "辨治风湿一例", 《爱爱医》 *

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105582204A (en) * 2015-09-09 2016-05-18 张苗 Traditional Chinese medicine for treating Still disease

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Application publication date: 20150429

RJ01 Rejection of invention patent application after publication