CN103157006B - Oral traditional Chinese medicine formula for treating osteoarthritis - Google Patents

Abstract

The invention discloses an oral traditional Chinese medicine prescription for treating osteoarthritis, which is composed of the following traditional Chinese medicine raw materials in the following weight ratio: Codonopsis 10-12 grams, Radix Astragali 10-15 grams, Atractylodes macrocephala 10-12 grams, Rhizoma Chuanxiong 6-9 grams, Radix Paeoniae Alba 10 grams -15g, Clematis (made with vinegar) 10-15g, Guizhi 6-9g, Notopterygium 6-9g, Duhuo 6-9g, Tengshiteng 9-12g, Wujiapi 9-12g , Rhizoma Drynaria 10-15 grams, Achyranthes bidentata 6-10 grams, Yuanhu (made with vinegar) 6-10 grams, safflower 3-6 grams, Caulis Spatholobus 10-15 grams, Pinellia 6-10 grams , 6-9 grams of tangerine peel, 9-12 grams of poria cocos, 10-20 grams of sea clam powder, 6-9 grams of Polygonatum odoratum, 2-4 grams of licorice. The invention has the advantages of pure traditional Chinese medicine preparation without toxic and side effects. The material is convenient and the price is low. The dialectical treatment is carried out by replenishing qi, nourishing blood and strengthening bones, promoting qi, promoting blood circulation and removing blood stasis, expelling wind and dampness to relieve pain, softening hard masses and clearing collaterals, etc., the curative effect is remarkable, and the effective rate is over 98%.

Description

Oral Traditional Chinese Medicine Prescriptions for Treating Osteoarthritis

technical field

The invention relates to the field of traditional Chinese medicine manufacture and application, in particular to an oral Chinese medicine prescription for treating osteoarthritis.

Background technique

Osteoarthritis, also known as proliferative arthritis (bone hyperplasia), degenerative arthritis (bone degeneration), and hypertrophic arthritis (big joints), is a common disease that can occur in joints in various parts of the body. More common in middle-aged and elderly people. The main pathological changes are as follows: under the action of internal and external factors, the surface cells of the articular chondrocyte membrane undergo degenerative changes, forming lip-like hyperplasia, or bony lip; the attachment of articular ligaments is damaged, forming spinous hyperplasia, or bony spurs. These bony lips and spurs are collectively called osteophytes, and they cause joint pain, swelling, stiffness, and dysfunction. Modern medicine believes that the occurrence of this disease is related to many factors, including the interaction of mechanical and biological factors, such as trauma, nutrition, and changes in lysozyme. Traditional Chinese medicine classifies this disease into the category of "Bone Arthralgia", and believes that its pathogenic factors are: exogenous pathogenic factor caused by wind-cold dampness or strain and falling, falling and falling, internal injury caused by insufficient Qi and blood or deficiency of liver and kidney, thus leading to stagnation of Qi and blood stasis, network arterial blockage. The principles of treatment are to dispel wind and dampness, dispel cold and relieve pain, promote blood circulation and remove blood stasis, dredge collaterals and relax tendons, and strengthen muscles and bones. For the treatment of osteoarthritis, various hospitals and pharmacies have launched various traditional Chinese medicine preparations, but there are still many patients who do not get better after taking external and internal medicines, and seek medical advice everywhere. Some traditional Chinese medicines for external use are unsuitable for some patients due to their formulas, which can easily cause skin allergic reactions; traditional Chinese medicines that need to be soaked or applied externally are inconvenient to operate due to factors such as temperature and time.

Contents of the invention

The purpose of the present invention is to overcome the deficiencies of the prior art and provide an oral Chinese medicine prescription for treating osteoarthritis.

The present invention is achieved through the following technical solutions:

An oral Chinese medicine prescription for treating osteoarthritis, the Chinese medicine prescription is composed of the following Chinese medicine raw materials in weight ratio: Codonopsis 10-12 grams, Radix Astragali 10-15 grams, Atractylodes macrocephala 10-12 grams, Ligusticum chuanxiong 6-9 grams, Bai 10-15 grams of peony root, 10-15 grams of Clematis (made with vinegar), 6-9 grams of cassia twig, 6-9 grams of notopterygium, 6-9 grams of duhuo, 9-12 grams of terrazzo, 9-9 grams of Wujiapi 12 grams, Rhizoma Drynaria 10-15 grams, Achyranthes bidentata 6-10 grams, Yuanhu (made with vinegar) 6-10 grams, safflower 3-6 grams, Caulis Spatholobus 10-15 grams, Pinellia 6- 10 grams, 6-9 grams of tangerine peel, 9-12 grams of poria cocos, 10-20 grams of sea clam powder, 6-9 grams of Polygonatum odoratum, 2-4 grams of licorice.

Preferably, the traditional Chinese medicine prescription is composed of the following traditional Chinese medicine raw materials in weight ratio: Codonopsis 11 grams, Astragalus 13 grams, Atractylodes macrocephala 11 grams, Rhizoma Chuanxiong 7 grams, Radix Paeoniae Alba 13 grams, Clematis (made with vinegar) 13 grams, Guizhi 7 grams, 7 grams of notopterygium, 7 grams of duhuo, 10 grams of safflower, 11 grams of Wujiapi, 12 grams of drynaria, 8 grams of Achyranthes bidentata, 8 grams of Yuanhu (made with vinegar), 5 grams of safflower, chicken 13 grams of vine, 8 grams of Pinellia, 7 grams of tangerine peel, 10 grams of Poria cocos, 15 grams of sea clam powder, 7 grams of Polygonatum odoratum, and 3 grams of licorice.

The oral Chinese medicine prescription for treating osteoarthritis provided by the present invention is a daily dose, and can be made into tablets, pills, capsules, granules or powders under modern biotechnology. Oral 3 times a day, 20 days as a course of treatment, usually 1-2 courses of treatment. This Chinese medicine prescription can also be used to treat rheumatic lumbago and leg pain. It should be noted: menstruation, pregnant women, suppurative arthritis, peptic ulcer and those with bleeding tendency are contraindicated; patients with red and swollen osteoarthritis should be used with caution.

The traditional Chinese medicine prescription provided by the invention mainly achieves the purpose of effectively treating osteoarthritis by nourishing qi, nourishing blood and strengthening bones, promoting qi and promoting blood circulation to remove blood stasis, expelling wind and dampness to relieve pain, softening hard masses, resolving stagnation and dredging collaterals. The properties of each drug in the traditional Chinese medicine prescription are as follows:

Codonopsis: sweet, slightly warm. Invigorate the middle and replenish qi, nourish blood and promote body fluid.

Radix Astragali: sweet, slightly warm. Invigorate qi and promote yang, solidify the surface and stop sweating, diuretic and reduce swelling, detoxify, expel pus and promote granulation.

Atractylodes macrocephala: sweet, bitter, warm. Invigorate the spleen and replenish qi, dry dampness and diuresis, solidify the surface and stop perspiration.

Rhizoma Chuanxiong: pungent, bitter, warm. Promoting qi and blood circulation, expelling wind and relieving pain, combined with angelica, white peony root, and rehmannia root to nourish blood and enter the camp.

Radix Paeoniae Alba: Bitter, sour, slightly cold. Nourishing blood and regulating menstruation, softening the liver and relieving pain, calming the liver and suppressing yang.

Clematis: pungent, salty, warm. Expelling wind and removing dampness, expelling phlegm and drinking, dispelling addiction and accumulation, eliminating bone phlegm.

Guizhi: pungent, bitter, warm. Dispelling muscle and sweating, warming meridian and dredging channels, dispelling wind and relieving pain.

Notopterygium: pungent, bitter, warm. Expelling wind and dampness, relieving the exterior and dispelling cold, the habit is biased towards the treatment of arthralgia and pain in the upper part of the body.

Independent Liver: pungent, bitter, warm. Expelling wind and dampness, relieving the exterior and dispelling cold, the habit is biased towards the treatment of arthralgia in the lower part of the body.

Radix Sinensis: bitter, slightly cold. Expelling wind and removing dampness, dredging channels and activating collaterals, cooling blood and detumescence.

Radix Wujiapi: pungent, warm. Dispelling wind and dampness, nourishing liver and kidney, strengthening muscles and bones, inducing diuresis and reducing swelling.

Drynaria: bitter, warm. Tonify the liver and kidney, strengthen the muscles and bones, reconnect the tendons and bones to heal injuries, and dispel rheumatism.

Achyranthes bidentata: bitter, sour, flat. Strengthen the bones and joints, promote blood circulation and stimulate the menstrual flow, and induce fire (blood) to descend.

Flos Carthami: pungent, warm. Promoting blood circulation, promoting menstrual flow, dispelling blood stasis, harmonizing blood and relieving pain.

Spatholobus Spatholobus: bitter, warm. Enriching blood and promoting blood circulation, dredging channels and collaterals, expelling rheumatism.

Yuan Hu: pungent, bitter, warm. Promoting blood circulation and removing blood stasis, promoting qi circulation and relieving pain. Qi stagnation in blood circulation, blood stagnation in ventilation.

Method Pinellia: pungent, warm. Toxic, dampness-drying and phlegm-resolving, reducing adverse flow rate and relieving vomiting, reducing swelling and hemostasis. After processing, the toxicity of Pinellia is almost reduced to zero.

Tangerine peel: pungent, bitter, warm. Drying dampness and resolving phlegm, promoting qi and relieving stomach pain.

Poria cocos: sweet, light, flat. Invigorate the spleen and invigorate the middle, promote diuresis and dampness, calm the mind and calm the nerves.

Sea clam powder: bitter, salty, flat. Softens hard mass and dissipates stagnation, clears lung and resolves phlegm.

Polygonatum odoratum: sweet, flat. Nourishes yin and promotes body fluid (treats lung and stomach yin deficiency), has a strong heart effect.

Glycyrrhizae: tonify the middle and replenish qi, reduce heat and detoxify, eliminate phlegm and relieve cough, and harmonize medicinal properties.

In the case of osteoarthritis with insufficient Qi and blood, it is necessary to nourish Qi and blood first, and then to promote Qi and blood circulation. This is because qi is born and transformed by blood, and blood is transported by qi. If only Qi is circulated without replenishing Qi, it will be difficult to circulate Qi, and it will be difficult to activate blood. Paeoniae Alba, Rhizoma Chuanxiong, and Caulis Spatholobus in the prescription can benefit the liver, nourish blood and nourish the body. Ligusticum chuanxiong is originally a thing for invigorating blood, but when it is compatible with white peony root, it can generate blood vessels and unblock yin. Here, why do not use "Dang Gui", the key medicine for nourishing blood and promoting blood circulation, because this medicine is too nourishing and greasy, and people with weak spleen and stomach will easily cause diarrhea if taken. Although Chuanxiong’s blood-tonifying power is not as good as that of angelica, its blood-activating power is stronger than that of angelica, and it can reach the top of the head when it goes up, and it can reach the knees when it goes down. At the same time, five flavors of qi-invigorating medicines such as Codonopsis pilosula, Astragalus root, Atractylodes macrocephala, Poria cocos, and licorice are used in the prescription to greatly invigorate the acquired qi and penetrate all channels. Under the double nourishment of qi and blood and the filling of qi and blood, the safflower, Yuanhu, Chuanxiong, Achyranthes bidentata, Caulis Spatholobus, etc. in the prescription can effectively promote qi, activate blood and remove blood stasis. After frying, the effect of promoting qi and relieving pain is multiplied by Yuanhu vinegar, which can promote stagnation of qi in blood and stagnation of blood in ventilation. Although bone spurs, bone spurs and other osteophytes are difficult to eliminate, the clematis in the prescription has a unique effect of eliminating osteophytes. After the medicine is made into vinegar, it not only enhances the effect of eliminating osteophytes, but also combines with Guizhi, Qianghuo, Duhuo, Wujia The effect of searching for wind and numbness is also greatly enhanced when used in combination with Pittonia japonica, Caulis Spatholobus, and Spathiphyllum. Among them, notopterygium tends to treat rheumatism in the upper part of the body; Duhuo tends to treat rheumatism below the waist and knees; It has the effect of solidifying the interior of the interstitial space and nourishing the body; Guizhi and Poria cocos are required together. For patients with fluid accumulation in the joint cavity, it can warm the yang, transform water and promote dampness, and can reduce swelling. It is cold and cool in nature, so it is especially suitable for people with redness, swelling and heat of osteoarthritis. And because the hot and warm medicines in the prescription are mostly used, it needs to be supplemented with a small amount of cool medicine to suppress its overheating, so it is suitable for different individuals and syndromes. Besides, the formation of osteophytes is also closely related to the deficiency of the liver and kidney, because the liver governs the tendons and kidneys govern the bones, and the drynaria fortunei, achyranthes bidentata, and acanthus root in the prescription can benefit the liver and kidney, greatly tonify the acquired vitality, and can relax the meridians Activate the collaterals, strengthen the tendons and bones, and then repair the damaged perichondrium. Osteophytes are not real living bones, but are gradually calcified by some dead perichondrial cells plus phlegm coagulation and blood stasis. Its structure is relatively fragile and can be differentiated by drugs. However, there is no large dose of Clematis in the prescription. This is because taking large doses of Clematis for a long time has the disadvantage of depleting true energy and is not suitable for people with weak constitutions. Although the dosage in the prescription is not large, it is also compatible with many supplements Qi medicine. Practice has proved that among the medicines for promoting blood circulation and removing blood stasis and expelling wind and dampness, the combination of pinellia, tangerine peel, and sea clam powder can greatly enhance the effect of removing blood stasis, resolving coagulation, softening and resolving hard masses, and the effect is better than increasing the dosage of clematis. , if it is not used, the curative effect will be obviously weakened. The toxicity of the French pinellia meridian is very small after being processed, but after long-term use, the medicine and tangerine peel can damage the lung yin and stomach yin because of being too pungent, so a small amount of Polygonatum odoratum is added to the prescription to nourish the yin of the lung and stomach and promote body fluid , thereby reducing its side effects. The licorice in the last prescription can reconcile the other medicines, relieve the severe symptoms, and keep the righteousness. Looking at the 22 medicines in the whole prescription, this is because the formation factors of osteoarthritis are relatively complex. Although there are many medicines, the combination of monarchs, ministers, assistants and envoys is appropriate and meticulous, and is suitable for different individuals and syndromes. The medicinal effect of the whole prescription is relatively mild, nourishing but not greasy, melting without stagnation, breaking without damaging the righteousness.

The present invention has the following advantages earlier than prior art:

The oral Chinese medicine prescription for treating osteoarthritis provided by the invention is a pure Chinese medicine preparation, has no toxic and side effects, and greatly reduces the pain and medical expenses of western medicine operations. And the 22 kinds of medicines of this Chinese medicine prescription are all very common, and it is convenient to draw materials, cheap, and easy to take. Among them, Clematis has the unique curative effect of eliminating osteophytes, coupled with the compatibility of other medicines, it can be dialectical by nourishing qi, nourishing blood and strengthening bones, promoting qi, activating blood and removing blood stasis, dispelling wind and dampness, relieving pain, softening hard masses, resolving stagnation and dredging collaterals, etc. Administer. This traditional Chinese medicine prescription has been clinically used to treat osteoarthritis for many years, with remarkable curative effect, and the effective rate exceeds 98%, which is suitable for clinical popularization and application.

Detailed ways

The embodiments of the present invention are described in detail below. This embodiment is implemented on the premise of the technical solution of the present invention, and detailed implementation methods and specific operating procedures are provided, but the protection scope of the present invention is not limited to the following implementation example.

Embodiment one

The oral Chinese medicine prescription for the treatment of osteoarthritis provided by the present embodiment is made up of the following Chinese medicine raw materials in weight ratio: Codonopsis 11 grams, Radix Astragali 13 grams, Atractylodes Rhizoma Atractylodes Rhizome 11 grams, Rhizoma Chuanxiong 7 grams, Radix Paeoniae Alba 13 grams, Clematis (vinegar-made ) 13 grams, Guizhi 7 grams, Notopterygium 7 grams, Duhuo 7 grams, Caterpillar 10 grams, Wujiapi 11 grams, Drynaria fortunei 12 grams, Achyranthes bidentata 8 grams, Yuanhu (vinegar) 8 grams, 5 grams of safflower, 13 grams of Caulis Spatholobus, 8 grams of Pinellia, 7 grams of tangerine peel, 10 grams of Poria cocos, 15 grams of sea clam powder, 7 grams of Polygonatum odoratum, and 3 grams of licorice.

Embodiment two

The oral Chinese medicine prescription for the treatment of osteoarthritis provided by the present embodiment is made up of the following Chinese medicine raw materials in weight ratio: Codonopsis 10 grams, Radix Astragali 10 grams, Atractylodes macrocephala 10 grams, Rhizoma Chuanxiong 6 grams, Radix Paeoniae Alba 10 grams, Clematis clematis (made with vinegar) ) 10 grams, Guizhi 6 grams, Notopterygium 6 grams, Duhuo 6 grams, Caterpillar 9 grams, Wujiapi 9 grams, Rhizoma Drynaria 10 grams, Achyranthes bidentata 6 grams, Yuanhu (made with vinegar) 6 grams, 3 grams of safflower, 10 grams of Caulis Spatholobus, 6 grams of Pinellia, 6 grams of tangerine peel, 9 grams of Poria cocos, 10 grams of sea clam powder, 6 grams of Polygonatum odoratum, and 2 grams of licorice.

Embodiment three

The oral Chinese medicine prescription for the treatment of osteoarthritis provided by the present embodiment is made up of the following traditional Chinese medicine raw materials in weight ratio: Codonopsis 12 grams, Astragalus 15 grams, Atractylodes macrocephala 12 grams, Rhizoma Chuanxiong 9 grams, Radix Paeoniae Alba 15 grams, Clematis clematis (made with vinegar) ) 15 grams, Guizhi 9 grams, Notopterygium 9 grams, Duhuo 9 grams, Caterpillar 12 grams, Wujiapi 12 grams, Drynaria fortunei 15 grams, Achyranthes bidentata 10 grams, Yuanhu (made with vinegar) 10 grams, 6 grams of safflower, 15 grams of Caulis Spatholobus, 10 grams of Pinellia, 9 grams of tangerine peel, 12 grams of Poria cocos, 20 grams of sea clam powder, 9 grams of Polygonatum odoratum, 4 grams of licorice.

The above three embodiments all can be made into tablet, pill, capsule granule or powder under modern biotechnology.

The traditional Chinese medicine prescriptions prepared in the above three examples have been used clinically for many years, and 32 patients were treated. Among them, 30 people were cured after taking the above traditional Chinese medicine prescriptions, and after 1-2 courses of treatment, the other 2 people got better. basically disappeared. Among them, the least medication is 15 days, and the maximum is 30 days. And no recurrence was found in the cured patients. The clinical effective rate of this traditional Chinese medicine prescription exceeds 98%, and the curative effect is remarkable, which is worthy of further popularization and application.

The above descriptions are only preferred embodiments of the invention, and are not intended to limit the invention. Any modifications, equivalent replacements and improvements made within the spirit and principles of the invention shall be included in this invention. within the protection scope of inventions and creations.

Claims (2)

1. an oral Chinese medicine prescription for the treatment of osteoarthritis, characterized in that, said Chinese medicine prescription is made up of the following Chinese medicine raw materials in weight ratio: Codonopsis 10-12 grams, Radix Astragali 10-15 grams, Atractylodes macrocephala 10-12 grams, Rhizoma Chuanxiong 6-9 grams, 10-15 grams of white peony root, 10-15 grams of vinegar clematis, 6-9 grams of cassia twig, 6-9 grams of notopterygium, 6-9 grams of duhuo, 9-12 grams of scorpion vine, five Jiapi 9-12 grams, Rhizoma Drynaria 10-15 grams, Achyranthes bidentata 6-10 grams, vinegar-made Yuanhu 6-10 grams, safflower 3-6 grams, Miltonia Spatholobus 10-15 grams, Pinellia chinensis 6-10 grams, 6-9 grams of tangerine peel, 9-12 grams of poria cocos, 10-20 grams of sea clam powder, 6-9 grams of Polygonatum odoratum, 2-4 grams of licorice. 2. The oral Chinese medicine prescription for the treatment of osteoarthritis as claimed in claim 1, characterized in that, said Chinese medicine prescription is made up of the following Chinese medicine raw materials in weight ratio: 11 grams of Codonopsis pilosula, 13 grams of Radix Astragali, 11 grams of Atractylodes Rhizome, 7 grams of Rhizoma Chuanxiong. 13 grams of Radix Paeoniae Alba, 13 grams of Vinegar Clematis, 7 grams of Guizhi, 7 grams of Notopterygium, 7 grams of Duhuo, 10 grams of Rhododendron, 11 grams of Wujiapi, 12 grams of Drynaria, and 8 grams of Achyranthes bidentata 8 grams, 8 grams of vinegar-made Yuanhu, 5 grams of safflower, 13 grams of Millet, 8 grams of Pinellia, 7 grams of tangerine peel, 10 grams of Poria cocos, 15 grams of sea clam powder, 7 grams of Polygonatum odoratum, and 3 grams of licorice.