CN1277577C

CN1277577C - Chinese traditional medicine for treating cerebral thrombosis, preparation method and application

Info

Publication number: CN1277577C
Application number: CNB2004100306954A
Authority: CN
Inventors: 周传红; 周长伟
Original assignee: Individual
Current assignee: Individual
Priority date: 2004-04-06
Filing date: 2004-04-06
Publication date: 2006-10-04
Anticipated expiration: 2024-04-06
Also published as: CN1562305A

Abstract

The present invention relates to a traditional Chinese medicine for treating cerebral thrombosis, a method and the application thereof for solving the problems of the existing medicines in slow medicinal effect and easy relapse after healing. The traditional Chinese medicine comprises the following crude drugs: inula flower, red ochre, uncaria, fresh oyster shell, abalone shell, earthworm, leech, gadfly, centipede, stiff silkworm, prism tuber, ginseng, radix ophiopogonis, schisandra, radix rehmanniae, scrophularia, raw radix et rhizoma rhei, rhizoma arisaematis, Rhizoma Acori Tatarinowii, fleece-flower root, morinda root, tortoise plastron, dendrobe, radix paeoniae alba, papaya, licorice root, Radix Cyathulae, codonopsis pilosula, dahurian angelica, Herba Cistanches, curcuma, astragalus root, balloon flower, Fructus Aurantii Immaturus, fried hawkthorn, fried malt, fired medicated leaven and pericarpium citri reticulatae, wherein medicines are made after gadfly feet and wings need to be removed and the rhizoma arisaematis is soaked in animal bile; the dendrobe, the fresh oyster shell, the abalone shell, the red ochre and the tortoise plastron in the medicinal broth need to be decocted earlier before the uncaria. Therefore, the traditional Chinese medicine for treating cerebral thrombosis has the advantages of fast medicinal effect, short treatment course, obvious curative effect, high cure rate, low relapse rate after healing and low treatment cost.

Description

The Chinese medicine and the application thereof of treatment cerebral embolism

Technical field

The present invention relates to control the medicine of thrombotic disease, particularly relate to a kind of Chinese medicine for the treatment of cerebral embolism, the invention still further relates to the application of this Chinese medicine.

Background technology

Cerebral embolism, the traditional Chinese medical science claim apoplexy again.Be with hemiplegia, crooked mouth and tongue, stiff tongue speech plug or aphasia, refreshing knowledge unconsciousness is the common acute illness of clinical main performance.At present traditional Chinese medical science scholar thinks: mainly containing the patient internal injury being long-pending usually of cerebral embolism decreased, and the heart, liver, kidney three dirty imbalance of YIN and YANG in the change that has intense feelings, or are drunk and are satiated with food, or exhaustion due to sexual indulgence, or inducement such as askew heresy invasion and attack and rising.Its pathogenesis develops comparatively complicated, and to get up mainly be that empty (deficiency of YIN, the deficiency of vital energy), fire (liver-fire, heart-fire), wind (liver-wind), expectorant (wind-phlegm, damp-phlegm), gas (QI rising in reverse order), blood six aspects such as (blood stasis) interact under certain condition, synergistic result but conclude.At present the doctor trained in Western medicine scholar thinks: its cause of disease has endothelial cell damage, the change of the change of blood fluidised form and blood itself, it shows as the blood that is flowing in the body, in blood vessel, condense or blood in some composition the sticking phenomenon that collects takes place.The primary disease morbidity is unexpected, but the state of an illness has the difference of the order of importance and emergency, and the disability rate of critically ill patient is very high; Primary disease is in case generation is difficult to treatment mostly, and especially the apoplectic coma person is not good after healing, so prevent extremely important.It is slow that the medicine of existing treatment cerebral embolism has produce effects, and the course of treatment is long, more easily recurrence of back, and cure rate is low, the treatment defect of high cost.

Summary of the invention

The objective of the invention is to overcome the defective of prior art, the Chinese medicine that a kind of produce effects is fast, the back of healing is difficult for the treatment cerebral embolism of recurrence is provided.

For achieving the above object, the present invention's crude drug for the treatment of the Chinese medicine of cerebral embolism comprises Flos Inulae, Haematitum, Ramulus Uncariae Cum Uncis, Concha Ostreae, Concha Haliotidis, Pheretima, Hirudo, Tabanus, Scolopendra, Bombyx Batryticatus, rhizoma sparganic, Radix Ginseng, Radix Ophiopogonis, Fructus Schisandrae Chinensis, the Radix Rehmanniae, Radix Scrophulariae, gives birth to Radix Et Rhizoma Rhei, Rhizoma Arisaematis, Rhizoma Acori Graminei, Radix Polygoni Multiflori, Radix Morindae Officinalis, Carapax et Plastrum Testudinis, Herba Dendrobii, the Radix Paeoniae Alba, Fructus Chaenomelis, Radix Glycyrrhizae, Radix Cyathulae, Radix Codonopsis, the Radix Angelicae Dahuricae, Herba Cistanches, Radix Curcumae, the Radix Astragali, Radix Platycodonis.Herba Cistanches can be Herba Cistanches, Herba Cistanches, Herba Boschniakiae Rossicae.

As optimization, its crude drug also comprises Fructus Aurantii Immaturus.Fructus Aurantii Immaturus is used to reduce phlegm, aid digestion and absorption.

As optimization, its crude drug also comprises JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata).JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) be used for being good for the stomach and.

As optimization, its crude drug also comprises Pericarpium Citri Reticulatae Viride.Pericarpium Citri Reticulatae Viride is used for circulation of qi promoting to help blood capable.

The drug regimen principle of Chinese medicine of the present invention is: Flos Inulae, Haematitum, Ramulus Uncariae Cum Uncis, Concha Ostreae, Concha Haliotidis, Pheretima, Hirudo, Tabanus, Scolopendra, Bombyx Batryticatus, rhizoma sparganic are used for liver-smoothing, qi-regulating, phlegm reduction of blood circulation promoting.Radix Ginseng, Radix Ophiopogonis, Fructus Schisandrae Chinensis, the Radix Rehmanniae, Radix Scrophulariae, give birth to that Radix Et Rhizoma Rhei, Rhizoma Arisaematis, Rhizoma Acori Graminei, Radix Polygoni Multiflori, Radix Morindae Officinalis, Carapax et Plastrum Testudinis are used for YIN nourishing blood, put out endogenous wind, the heat of reducing phlegm, clearly refreshingly know.Herba Dendrobii, the Radix Paeoniae Alba, Fructus Chaenomelis, Radix Glycyrrhizae, Radix Cyathulae, Radix Codonopsis, the Radix Angelicae Dahuricae, Herba Cistanches, Radix Curcumae be used to nourish blood regulating liver-QI, relaxing muscles and tendons and activating QI and blood in the collateral impel human body to restore.Solely get Radix Astragali tonifying Qi and lifting yang simply, the Radix Platycodonis priming is up.

As optimization, the weight proportion of crude drug is Flos Inulae 6-10, Haematitum 6-10, Ramulus Uncariae Cum Uncis 10-15, Concha Ostreae 20-30, Concha Haliotidis 20-30, Pheretima 6-10, Hirudo 6-10, Tabanus 6-10, Scolopendra 6-10, Bombyx Batryticatus 3-6, rhizoma sparganic 6-15, Radix Ginseng 6-10, Radix Ophiopogonis 10-25, Fructus Schisandrae Chinensis 6-15, Radix Rehmanniae 10-15, Radix Scrophulariae 10-15, give birth to the 3-6 of Radix Et Rhizoma Rhei, Rhizoma Arisaematis 5-10, Rhizoma Acori Graminei 6-10, Radix Polygoni Multiflori 15-30, Radix Morindae Officinalis 9-15, Carapax et Plastrum Testudinis 15-30, Herba Dendrobii 20-30, Radix Paeoniae Alba 10-15, Fructus Chaenomelis 12-25, Radix Glycyrrhizae 6-10, Radix Cyathulae 20-30, Radix Codonopsis 30-45, Radix Angelicae Dahuricae 6-9, Herba Cistanches 6-12, Radix Curcumae 9-12, Radix Astragali 30-45, Radix Platycodonis 7-10.

As optimization, its crude drug comprises that also weight proportion is the Fructus Aurantii Immaturus of 6-9.

As optimization, its crude drug comprises that also weight proportion is the JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) of 10-20.JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) can replace with Semen Raphani.JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) market can be purchased, can oneself prepare, and promptly be haw berry, Fructus Hordei Germinatus and the Massa Medicata Fermentata of parching to brown.

As optimization, its crude drug comprises that also weight proportion is the Pericarpium Citri Reticulatae Viride of 6-10.

Preparation method of Chinese medicine of the present invention, crude drug Tabanus need be removed sufficient wing, Rhizoma Arisaematis need be with making medicine behind the animal bile infuse again; Crude drug Herba Dendrobii in the decoction, Concha Ostreae, Concha Haliotidis, Haematitum, Carapax et Plastrum Testudinis, need be decocted first, behind the Ramulus Uncariae Cum Uncis down; The best processed with honey of Radix Glycyrrhizae.

The decoction amount of water is three times of crude drug gross weight.Obtain after the decoction and crude drug gross weight decoction finished medicines about equally.Instructions of taking: the lighter obeys one pair (frying in shallow oil once) evening every day, and seven days is a course of treatment; One pair of heavy person every day, fry in shallow oil twice, morning and evening service once, seven days is a course of treatment.

Chinese medicine of the present invention can also be used to prepare the Chinese medicine of treatment and prevention of brain thromboembolism, angina pectoris, hyperlipidemia, high blood viscosity, atherosclerosis and coronary heart disease.Certainly medicine of the present invention can also be used for the treatment of other thrombus diseases, as thrombophlebitis etc.

The dosage form of medicine of the present invention comprises decoction, powder, pill, capsule, injection.

The preparation method of the capsule of medicine of the present invention is: after crude drug was concocted, pulverize separately, mix homogeneously incapsulated, and about every powder charge 0.5 gram, obeyed the 3-6 grain at every turn.Be a course of treatment at one to twice, seven day every day.

Administrated method: the careful clothes of weakling, promptly first low dose is taken, after slowly carry out the transition to normal dose.It can be used for treatment and prevention of brain thrombosis, cerebral embolism, angina pectoris, hyperlipidemia, high blood viscosity, atherosclerosis and coronary heart disease, particularly cerebral infarction sequela is had very outstanding therapeutic effect.

Prove through long-term clinical application: medical instrument of the present invention has liver-smoothing, qi-regulating, phlegm reduction of blood circulation promoting, YIN nourishing blood, put out endogenous wind, the heat of reducing phlegm, clear refreshing know, nourish blood regulating liver-QI, relaxing muscles and tendons and activating QI and blood in the collateral impel human body to restore and the effect of tonifying Qi and lifting yang, compare with existing similar medicine that to have produce effects fast, short treating period, determined curative effect, the cure rate height, more the back is difficult for recurrence, the treatment cost is low, not only can cure the disease but also preventible advantage.

Medicine of the present invention is for extreme hyperactivity of the liver-yang, and the patient who disturbs on the wind-fire can nourishing YIN for suppressing the hyperactive YANG, suppressing the hyperactive liver to relieve the wind syndrome; For the wind-phlegm blood stasis, the patient of numbness resistance venation can eleminating phlegm and freeing channels; Real for the hot internal organs of expectorant, the patient who disturbs on the wind-phlegm, purging FU-organs can reduce phlegm; For the patient of blood stasis due to qi deficiency, can benefiting QI for activating blood circulation; For the patient of stirring of wind due to deficiency of YIN, can nourishing YIN to subdue liver-wind; For the patient who disturbs on the wind-fire, can clearing away heat and relieving the wind syndrome, purging FU-organs reduces phlegm; Cover the patient of the plug mind for phlegm-damp, can relieve dizziness, high fever, infantile convulsions, epilepsy, etc. by eliminating phlegm; For closing thinking person in the expectorant heat, can liver heat removing relieve dizziness, high fever, infantile convulsions, epilepsy, etc.; Lose for vigour and to take off, the patient that the mind is at random can supplementing QI to revive YANG, and rescuing YIN takes off admittedly.For hemiplegia person, can inrigorating qi and promoting blood circulation, dredge the meridian passage, suppressing the hyperactive liver and subsiding YANG, calming wind and dredging collateral.For the patient of dysphonia, the expectorant of can dispeling the wind, inducing resuscitation collateral dredging, the sharp key of enriching yin and nourishing kidney, waking up the patient from unconsciousness by dissipating phlegm.

Now exemplifying one of them model case is further described:

Zhang Shi suddenly, the woman, 78 years old, Guo Cang township, Wenshang County, Shandong Province appointed storehouse people from village, and the autumn in 2003 was suffered from cerebral thrombosis, and through the western medical treatment DeGrain, go to a doctor (ill wheat harvesting period) in here afterwards, and symptom: left lower extremity is paralysed fully, the left upper extremity function limitation.Take course of treatment of medicine of the present invention, 7 days is a course of treatment, takes one pair every day, can walk under other people assisting in.After taking 2 course of treatment medicines of the present invention again, can oneself walking.

The specific embodiment

Do further explanation below in conjunction with concrete example:

The weight proportion of crude drug that the present invention treats the Chinese medicine of cerebral embolism is a Flos Inulae 6,8,10, Haematitum 6,8,10, Ramulus Uncariae Cum Uncis 10,12,15, Concha Ostreae 20,25,30, Concha Haliotidis 20,25,30, Pheretima 6,8,10, Hirudo 6,8,10, Tabanus 6,8,10, Scolopendra 6,8,10, Bombyx Batryticatus 3,4,6, rhizoma sparganic 6,10,15, Radix Ginseng 6,8,10, Radix Ophiopogonis 10,18,25, Fructus Schisandrae Chinensis 6,10,15, the Radix Rehmanniae 10,12,15, Radix Scrophulariae 10,13,15, give birth to Radix Et Rhizoma Rhei 3,4,6, Rhizoma Arisaematis 5,7,10, Rhizoma Acori Graminei 6,8,10, Radix Polygoni Multiflori 15,23,30, Radix Morindae Officinalis 9,12,15, Carapax et Plastrum Testudinis 15,23,30, Herba Dendrobii 20,25,30, the Radix Paeoniae Alba 10,12,15, Fructus Chaenomelis 12,18,25, Radix Glycyrrhizae 6,8,10, Radix Cyathulae 20,25,30, Radix Codonopsis 30,36,45, the Radix Angelicae Dahuricae 6,7,9, Herba Cistanches 6,9,12, Radix Curcumae 9,10,12, the Radix Astragali 30,38,45, Radix Platycodonis 7,8,10.Unit of weight is gram.

Flos Inulae 6,8,10, Haematitum 6,8,10, Ramulus Uncariae Cum Uncis 10,12,15, Concha Ostreae 20,25,30, Concha Haliotidis 20,25,30, Pheretima 6,8,10, Hirudo 6,8,10, Tabanus 6,8,10, Scolopendra 6,8,10, Bombyx Batryticatus 3,4,6, rhizoma sparganic 6,10,15, Radix Ginseng 6,8,10, Radix Ophiopogonis 10,18,25, Fructus Schisandrae Chinensis 6,10,15, the Radix Rehmanniae 10,12,15, Radix Scrophulariae 10,13,15, give birth to Radix Et Rhizoma Rhei 3,4,6, Rhizoma Arisaematis 5,7,10, Rhizoma Acori Graminei 6,8,10, Radix Polygoni Multiflori 15,23,30, Radix Morindae Officinalis 9,12,15, Carapax et Plastrum Testudinis 15,23,30, Herba Dendrobii 20,25,30, the Radix Paeoniae Alba 10,12,15, Fructus Chaenomelis 12,18,25, Radix Glycyrrhizae 6,8,10, Radix Cyathulae 20,25,30, Radix Codonopsis 30,36,45, the Radix Angelicae Dahuricae 6,7,9, Herba Cistanches 6,9,12, Radix Curcumae 9,10,12, the Radix Astragali 30,38,45, Radix Platycodonis 7,8,10, Fructus Aurantii Immaturus 6,8,9.Unit of weight is gram.

Flos Inulae 6,8,10, Haematitum 6,8,10, Ramulus Uncariae Cum Uncis 10,12,15, Concha Ostreae 20,25,30, Concha Haliotidis 20,25,30, Pheretima 6,8,10, Hirudo 6,8,10, Tabanus 6,8,10, Scolopendra 6,8,10, Bombyx Batryticatus 3,4,6, rhizoma sparganic 6,10,15, Radix Ginseng 6,8,10, Radix Ophiopogonis 10,18,25, Fructus Schisandrae Chinensis 6,10,15, the Radix Rehmanniae 10,12,15, Radix Scrophulariae 10,13,15, give birth to Radix Et Rhizoma Rhei 3,4,6, Rhizoma Arisaematis 5,7,10, Rhizoma Acori Graminei 6,8,10, Radix Polygoni Multiflori 15,23,30, Radix Morindae Officinalis 9,12,15, Carapax et Plastrum Testudinis 15,23,30, Herba Dendrobii 20,25,30, the Radix Paeoniae Alba 10,12,15, Fructus Chaenomelis 12,18,25, Radix Glycyrrhizae 6,8,10, Radix Cyathulae 20,25,30, Radix Codonopsis 30,36,45, the Radix Angelicae Dahuricae 6,7,9, Herba Cistanches 6,9,12, Radix Curcumae 9,10,12, the Radix Astragali 30,38,45, Radix Platycodonis 7,8,10, Fructus Aurantii Immaturus 6,8,9, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 10-20.Unit of weight is gram.

Flos Inulae 6,8,10, Haematitum 6,8,10, Ramulus Uncariae Cum Uncis 10,12,15, Concha Ostreae 20,25,30, Concha Haliotidis 20,25,30, Pheretima 6,8,10, Hirudo 6,8,10, Tabanus 6,8,10, Scolopendra 6,8,10, Bombyx Batryticatus 3,4,6, rhizoma sparganic 6,10,15, Radix Ginseng 6,8,10, Radix Ophiopogonis 10,18,25, Fructus Schisandrae Chinensis 6,10,15, the Radix Rehmanniae 10,12,15, Radix Scrophulariae 10,13,15, give birth to Radix Et Rhizoma Rhei 3,4,6, Rhizoma Arisaematis 5,7,10, Rhizoma Acori Graminei 6,8,10, Radix Polygoni Multiflori 15,23,30, Radix Morindae Officinalis 9,12,15, Carapax et Plastrum Testudinis 15,23,30, Herba Dendrobii 20,25,30, the Radix Paeoniae Alba 10,12,15, Fructus Chaenomelis 12,18,25, Radix Glycyrrhizae 6,8,10, Radix Cyathulae 20,25,30, Radix Codonopsis 30,36,45, the Radix Angelicae Dahuricae 6,7,9, Herba Cistanches 6,9,12, Radix Curcumae 9,10,12, the Radix Astragali 30,38,45, Radix Platycodonis 7,8,10, Fructus Aurantii Immaturus 6,8,9, JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 10-20, Pericarpium Citri Reticulatae Viride 6,8,10.Unit of weight is gram.

The preparation method of its decoction is: the crude drug Tabanus need go sufficient wing, Rhizoma Arisaematis need use the animal bile infuse, the Radix Glycyrrhizae processed with honey.Amount of water is three times of crude drug gross weight.Herba Dendrobii, Concha Ostreae, Concha Haliotidis, Haematitum, Carapax et Plastrum Testudinis need be decocted first one hour, added other crude drug, fried in shallow oil 20 minutes adding Ramulus Uncariae Cum Uncis, continued to fry in shallow oil 20 minutes.Obtain at last and crude drug gross weight finished product decoction about equally.

Instructions of taking: the lighter obeys one pair (frying in shallow oil once) evening every day, and seven days is a course of treatment; One pair of heavy person every day, fry in shallow oil twice, morning and evening service once, seven days is a course of treatment.

The preparation method of its capsule is: the crude drug Tabanus need go sufficient wing, Rhizoma Arisaematis need use the animal bile infuse, the Radix Glycyrrhizae processed with honey.After crude drug was concocted, pulverize separately, mix homogeneously incapsulated, and every powder charge 0.5 gram is obeyed the 3-6 grain at every turn.Be a course of treatment at one to twice, seven day every day.

Claims

1, a kind of Chinese medicine for the treatment of cerebral embolism, the weight proportion that it is characterized in that crude drug is Flos Inulae 6-10, Haematitum 6-10, Ramulus Uncariae Cum Uncis 10-15, Concha Ostreae 20-30, Concha Haliotidis 20-30, Pheretima 6-10, Hirudo 6-10, Tabanus 6-10, Scolopendra 6-10, Bombyx Batryticatus 3-6, rhizoma sparganic 6-15, Radix Ginseng 6-10, Radix Ophiopogonis 10-25, Fructus Schisandrae Chinensis 6-15, Radix Rehmanniae 10-15, Radix Scrophulariae 10-15, give birth to the 3-6 of Radix Et Rhizoma Rhei, Rhizoma Arisaematis 5-10, Rhizoma Acori Graminei 6-10, Radix Polygoni Multiflori 15-30, Radix Morindae Officinalis 9-15, Carapax et Plastrum Testudinis 15-30, Herba Dendrobii 20-30, Radix Paeoniae Alba 10-15, Fructus Chaenomelis 12-25, Radix Glycyrrhizae 6-10, Radix Cyathulae 20-30, Radix Codonopsis 30-45, Radix Angelicae Dahuricae 6-9, Herba Cistanches 6-12, Radix Curcumae 9-12, Radix Astragali 30-45, Radix Platycodonis 7-10.

2, the Chinese medicine of treatment cerebral embolism according to claim 1 wherein also adds crude drug Fructus Aurantii Immaturus 6-9.

3, the Chinese medicine of treatment cerebral embolism according to claim 2 wherein also adds crude drug JIAOSANXIAN (Fructus Crataegi, Fructus Hordei Germinatus, Massa Medicata Fermentata) 10-20.

4, the Chinese medicine of treatment cerebral embolism according to claim 3 wherein also adds crude drug Pericarpium Citri Reticulatae Viride 6-10.

5, the Chinese medicine of treatment cerebral embolism according to claim 1, crude drug Tabanus wherein removes sufficient wing, Rhizoma Arisaematis animal bile infuse.

6, according to the application of claim 1,2,3,4 or 5 described Chinese medicines at the Chinese medicine of preparation treatment and prevention of brain thromboembolism, angina pectoris, hyperlipidemia, high blood viscosity, atherosclerosis and coronary heart disease.