CN1304409A - 用于治疗抑郁症的吲哚-3-基-环己胺衍生物(5-ht1受体拮抗剂) - Google Patents
用于治疗抑郁症的吲哚-3-基-环己胺衍生物(5-ht1受体拮抗剂) Download PDFInfo
- Publication number
- CN1304409A CN1304409A CN99807010A CN99807010A CN1304409A CN 1304409 A CN1304409 A CN 1304409A CN 99807010 A CN99807010 A CN 99807010A CN 99807010 A CN99807010 A CN 99807010A CN 1304409 A CN1304409 A CN 1304409A
- Authority
- CN
- China
- Prior art keywords
- hydrogen
- phenyl
- compound
- alkyl group
- low alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5724498A | 1998-04-08 | 1998-04-08 | |
US09/057,244 | 1998-04-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN1304409A true CN1304409A (zh) | 2001-07-18 |
Family
ID=22009404
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN99807010A Pending CN1304409A (zh) | 1998-04-08 | 1999-04-07 | 用于治疗抑郁症的吲哚-3-基-环己胺衍生物(5-ht1受体拮抗剂) |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1070063A1 (fr) |
JP (1) | JP2002510682A (fr) |
CN (1) | CN1304409A (fr) |
AU (1) | AU3476599A (fr) |
CA (1) | CA2327360A1 (fr) |
WO (1) | WO1999051592A1 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2494300A (en) * | 1999-01-07 | 2000-07-24 | American Home Products Corporation | 3,4-dihydro-2h-benzo(1,4)oxazine derivatives |
US6221863B1 (en) | 1999-01-07 | 2001-04-24 | American Home Products Corp. | 3,4-dihydro-2H-benzo[1,4]oxazine derivatives |
TW546299B (en) * | 1999-01-07 | 2003-08-11 | Wyeth Corp | 3,4-dihydro-2H-benzo[1,4]oxazinyl-methyl-[3-(1H-indol-3-yl)-alkyl]-amines |
GB0203804D0 (en) | 2002-02-18 | 2002-04-03 | Glaxo Group Ltd | Compounds |
US7041697B2 (en) | 2002-09-12 | 2006-05-09 | Wyeth | Antidepressant cycloalkylamine derivatives of 2,3-dihydro-1,4-benzodioxan |
US6911445B2 (en) * | 2002-09-12 | 2005-06-28 | Wyeth | Antidepressant cycloalkylamine derivatives of heterocycle-fused benzodioxans |
US7276603B2 (en) | 2003-05-02 | 2007-10-02 | Wyeth | Benzofuranyl-and benzothienyl-piperazinyl quinolines and methods of their use |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3058980A (en) * | 1962-10-16 | Substitution products of benzo- | ||
US4612312A (en) * | 1984-07-30 | 1986-09-16 | Merrell Dow Pharmaceuticals Inc. | Glutarimide antianxiety and antihypertensive agents |
GB8719167D0 (en) * | 1987-08-13 | 1987-09-23 | Glaxo Group Ltd | Chemical compounds |
DK37790A (da) * | 1990-02-13 | 1991-08-14 | Novo Nordisk As | Indolderivater, deres fremstilling og anvendelse |
US5189179A (en) * | 1990-08-29 | 1993-02-23 | Merrell Dow Pharmaceuticals Inc. | Serotonin 5ht1a agonists |
US5468768A (en) * | 1994-01-06 | 1995-11-21 | Bristol-Myers Squibb Company | Antimigraine derivatives of indolylcycloalkanylamines |
US5521197A (en) * | 1994-12-01 | 1996-05-28 | Eli Lilly And Company | 3-<1-alkylenearyl>-4-<1,2,3,6-tetrahydropyridinyl>-and 3-<1-alkylenearyl>-4-piperidinyl-1h-indoles: new 5-HT1F agonists |
CZ288897A3 (cs) * | 1995-03-20 | 1998-02-18 | Eli Lilly And Company | V poloze 5-substituovaný 3-(1,2,3,6-tetrahydropyridin-4-yl)indol a 3-(piperidin-4-yl)indol a farmaceutický prostředek, který je obsahuje |
-
1999
- 1999-04-07 EP EP99916450A patent/EP1070063A1/fr not_active Withdrawn
- 1999-04-07 JP JP2000542313A patent/JP2002510682A/ja active Pending
- 1999-04-07 AU AU34765/99A patent/AU3476599A/en not_active Abandoned
- 1999-04-07 WO PCT/US1999/007606 patent/WO1999051592A1/fr not_active Application Discontinuation
- 1999-04-07 CN CN99807010A patent/CN1304409A/zh active Pending
- 1999-04-07 CA CA002327360A patent/CA2327360A1/fr not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2327360A1 (fr) | 1999-10-14 |
AU3476599A (en) | 1999-10-25 |
WO1999051592A1 (fr) | 1999-10-14 |
JP2002510682A (ja) | 2002-04-09 |
EP1070063A1 (fr) | 2001-01-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
WD01 | Invention patent application deemed withdrawn after publication |