CN1294135C - 作为蛋白激酶抑制剂的吡咯并嘧啶 - Google Patents

作为蛋白激酶抑制剂的吡咯并嘧啶 Download PDF

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Publication number
CN1294135C
CN1294135C CNB028119320A CN02811932A CN1294135C CN 1294135 C CN1294135 C CN 1294135C CN B028119320 A CNB028119320 A CN B028119320A CN 02811932 A CN02811932 A CN 02811932A CN 1294135 C CN1294135 C CN 1294135C
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Expired - Fee Related
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CNB028119320A
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Chinese (zh)
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CN1518552A (zh
Inventor
P·J·考克斯
T·N·马吉德
S·阿门道拉
S·D·德普雷
C·埃德林
B·L·佩德格雷弗特
F·阿莱
M·爱德华兹
B·博杜安
L·M·麦克雷
D·J·奥尔德斯
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Aventis Pharmaceuticals Inc
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Aventis Pharmaceuticals Inc
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Publication of CN1518552A publication Critical patent/CN1518552A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CNB028119320A 2001-06-23 2002-06-21 作为蛋白激酶抑制剂的吡咯并嘧啶 Expired - Fee Related CN1294135C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB0115393.1A GB0115393D0 (en) 2001-06-23 2001-06-23 Chemical compounds
GB0115393.1 2001-06-23
US30167801P 2001-06-28 2001-06-28
US60/301,678 2001-06-28

Publications (2)

Publication Number Publication Date
CN1518552A CN1518552A (zh) 2004-08-04
CN1294135C true CN1294135C (zh) 2007-01-10

Family

ID=9917225

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB028119320A Expired - Fee Related CN1294135C (zh) 2001-06-23 2002-06-21 作为蛋白激酶抑制剂的吡咯并嘧啶

Country Status (22)

Country Link
EP (1) EP1404676A1 (https=)
JP (1) JP4344607B2 (https=)
CN (1) CN1294135C (https=)
AU (1) AU2002314325B8 (https=)
BR (1) BR0210652A (https=)
CA (1) CA2451932C (https=)
CZ (1) CZ20033443A3 (https=)
EA (1) EA007415B1 (https=)
EC (1) ECSP034922A (https=)
EE (1) EE05432B1 (https=)
GB (1) GB0115393D0 (https=)
HU (1) HUP0400300A3 (https=)
ME (1) MEP19308A (https=)
NZ (1) NZ529766A (https=)
OA (1) OA12632A (https=)
PL (1) PL374096A1 (https=)
RS (1) RS51698B (https=)
SK (1) SK15882003A3 (https=)
TN (1) TNSN03144A1 (https=)
TR (1) TR200302242T2 (https=)
UA (1) UA76760C2 (https=)
WO (1) WO2003000695A1 (https=)

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Also Published As

Publication number Publication date
TR200302242T2 (tr) 2004-12-21
CA2451932C (en) 2009-12-29
AU2002314325B2 (en) 2009-01-08
JP4344607B2 (ja) 2009-10-14
BR0210652A (pt) 2004-08-10
OA12632A (en) 2006-06-14
NZ529766A (en) 2008-11-28
WO2003000695A1 (en) 2003-01-03
SK15882003A3 (sk) 2004-07-07
EA200400073A1 (ru) 2004-08-26
UA76760C2 (uk) 2006-09-15
HUP0400300A3 (en) 2010-12-28
EA007415B1 (ru) 2006-10-27
EP1404676A1 (en) 2004-04-07
CZ20033443A3 (en) 2004-03-17
GB0115393D0 (en) 2001-08-15
EE200400003A (et) 2004-02-16
PL374096A1 (en) 2005-09-19
RS99203A (sr) 2006-12-15
HUP0400300A2 (en) 2007-08-28
EE05432B1 (et) 2011-06-15
ECSP034922A (es) 2004-04-28
TNSN03144A1 (en) 2005-12-23
WO2003000695A8 (en) 2004-03-11
CA2451932A1 (en) 2003-01-03
CN1518552A (zh) 2004-08-04
MEP19308A (en) 2010-06-10
JP2005508300A (ja) 2005-03-31
RS51698B (sr) 2011-10-31
AU2002314325B8 (en) 2009-01-29

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