CN1285591C - 二聚化合物及其作为抗病毒剂的应用 - Google Patents

二聚化合物及其作为抗病毒剂的应用 Download PDF

Info

Publication number
CN1285591C
CN1285591C CNB028222474A CN02822247A CN1285591C CN 1285591 C CN1285591 C CN 1285591C CN B028222474 A CNB028222474 A CN B028222474A CN 02822247 A CN02822247 A CN 02822247A CN 1285591 C CN1285591 C CN 1285591C
Authority
CN
China
Prior art keywords
compound
virus
formula
acid
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB028222474A
Other languages
English (en)
Chinese (zh)
Other versions
CN1585765A (zh
Inventor
迈克尔·D.·道勒
贝蒂·吉恩
西蒙·J.·F.·麦克唐纳
安德鲁·McM.·梅森
达里尔·麦康奈尔
范·T.·T.·阮
斯蒂芬·E.·沙纳汉
文-洋·吴
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biota Scientific Management Pty Ltd
Original Assignee
Biota Scientific Management Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPR8798A external-priority patent/AUPR879801A0/en
Priority claimed from AUPS2600A external-priority patent/AUPS260002A0/en
Application filed by Biota Scientific Management Pty Ltd filed Critical Biota Scientific Management Pty Ltd
Publication of CN1585765A publication Critical patent/CN1585765A/zh
Application granted granted Critical
Publication of CN1285591C publication Critical patent/CN1285591C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CNB028222474A 2001-11-09 2002-11-08 二聚化合物及其作为抗病毒剂的应用 Expired - Fee Related CN1285591C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AUPR8798 2001-11-09
AUPR8798A AUPR879801A0 (en) 2001-11-09 2001-11-09 Novel chemical compounds and their use
AUPS2600 2002-05-27
AUPS2600A AUPS260002A0 (en) 2002-05-27 2002-05-27 Novel chemical compounds and their use

Publications (2)

Publication Number Publication Date
CN1585765A CN1585765A (zh) 2005-02-23
CN1285591C true CN1285591C (zh) 2006-11-22

Family

ID=25646840

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB028222474A Expired - Fee Related CN1285591C (zh) 2001-11-09 2002-11-08 二聚化合物及其作为抗病毒剂的应用

Country Status (12)

Country Link
US (2) US7157494B2 (enExample)
EP (1) EP1451182B1 (enExample)
JP (2) JP5183853B2 (enExample)
KR (1) KR100942492B1 (enExample)
CN (1) CN1285591C (enExample)
AT (1) ATE398122T1 (enExample)
CA (1) CA2462337C (enExample)
DE (1) DE60227100D1 (enExample)
DK (1) DK1451182T3 (enExample)
ES (1) ES2305300T3 (enExample)
PT (1) PT1451182E (enExample)
WO (1) WO2003040135A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1451182B1 (en) * 2001-11-09 2008-06-11 Biota Scientific Management Pty. Ltd. Dimeric compounds and their use as anti-viral agents
US7560587B2 (en) 2004-12-04 2009-07-14 Xerox Corporation Bis[urea-urethane] compounds
US7576235B2 (en) 2004-12-04 2009-08-18 Xerox Corporation Processes for preparing bis(urea-urethane) compounds
US7144450B2 (en) 2004-12-04 2006-12-05 Xerox Corporation Phase change inks containing trans-1,2-cyclohexane bis(urea-urethane) compounds
US7220300B2 (en) 2004-12-04 2007-05-22 Xerox Corporation Phase change inks containing bis(urea-urethane) compounds
US7314949B2 (en) 2004-12-04 2008-01-01 Xerox Corporation Trans-1,2-cyclohexane bis(urea-urethane) compounds
US7317122B2 (en) 2004-12-04 2008-01-08 Xerox Corporation Curable trans-1,2-cyclohexane bis(urea-urethane) compounds
US7153349B2 (en) 2004-12-04 2006-12-26 Xerox Corporation Phase change inks containing curable trans-1,2-cyclohexane bis(urea-urethane) compounds
CN100471848C (zh) * 2006-06-05 2009-03-25 中国医学科学院医药生物技术研究所 一组长链烷氧烷基取代唾液酸衍生物及其制备方法
CN108003065B (zh) * 2016-10-27 2021-01-08 中国石油化工股份有限公司 一种具有增稠作用的化合物和润滑脂以及它们的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9516276D0 (en) * 1995-08-08 1995-10-11 Biota Scient Management Chemical compounds
KR19990087449A (ko) * 1996-03-01 1999-12-27 리차드 웨드레이 인플루엔자 바이러스의 검출방법 및 이에 이용되는 화합물
US6153442A (en) * 1998-05-20 2000-11-28 Dade Behring Inc. Reagents and methods for specific binding assays
AUPP913999A0 (en) * 1999-03-12 1999-04-01 Biota Scientific Management Pty Ltd Novel chemical compounds and their use
AUPR001000A0 (en) 2000-09-08 2000-10-05 Biota Scientific Management Pty Ltd Novel chemical compounds and their use
EP1451182B1 (en) * 2001-11-09 2008-06-11 Biota Scientific Management Pty. Ltd. Dimeric compounds and their use as anti-viral agents
JP2010027130A (ja) 2008-07-17 2010-02-04 Sony Corp 装着機構および出力装置

Also Published As

Publication number Publication date
US20050038108A1 (en) 2005-02-17
CA2462337A1 (en) 2003-05-15
JP2005510519A (ja) 2005-04-21
KR20050044337A (ko) 2005-05-12
DK1451182T3 (da) 2008-10-27
EP1451182B1 (en) 2008-06-11
JP2010270130A (ja) 2010-12-02
EP1451182A4 (en) 2005-02-02
US20070293564A1 (en) 2007-12-20
PT1451182E (pt) 2008-09-17
CA2462337C (en) 2011-09-27
EP1451182A1 (en) 2004-09-01
CN1585765A (zh) 2005-02-23
ATE398122T1 (de) 2008-07-15
KR100942492B1 (ko) 2010-02-12
US7157494B2 (en) 2007-01-02
HK1068346A1 (en) 2005-04-29
JP5183853B2 (ja) 2013-04-17
WO2003040135A1 (en) 2003-05-15
DE60227100D1 (de) 2008-07-24
ES2305300T3 (es) 2008-11-01

Similar Documents

Publication Publication Date Title
CN1143853C (zh) 抗病毒化合物的制备方法
CN1185223C (zh) 新颖化合物,其合成方法及治疗用途
CN1285591C (zh) 二聚化合物及其作为抗病毒剂的应用
JP2016530314A (ja) アザ−ピリドン化合物およびその用途
CN1717227A (zh) 含类黄酮和薄荷醇的药物组合物
CN100345842C (zh) 二聚化合物及其作为抗病毒剂的用途
CN1427827A (zh) 用于抗菌的2-羟基-姆替林氨基甲酸酯衍生物
CN101035770A (zh) 可用作β-分泌酶(BACE)抑制剂的新的2-氨基-喹唑啉衍生物
CN1301993C (zh) 二聚化合物及其作为抗病毒剂的用途
CN1238762A (zh) 哌啶化合物
CN1585766A (zh) 二聚化合物及其作为抗病毒剂的应用
CN1662238A (zh) 肽去甲酰酶活化的前体药物
CN1239498C (zh) 作为ccr-3受体拮抗剂的取代的吡咯烷
HK1010191B (en) Method for manufacturing anti-viral compounds
HK1088594B (en) Novel compounds and methods for synthesis and therapy
HK1088594A1 (zh) 新颖化合物,其合成方法及治疗用途
CN1241184A (zh) 用于治疗骨质疏松的吲哚衍生物
AU2002336823A1 (en) Dimeric compounds and their use as anti-viral agents
HK1068347B (en) Dimeric compounds and their use as anti-viral agents

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20061122

Termination date: 20131108