CN1269832A - K－配体－新的免疫系统蛋白 - Google Patents
K－配体－新的免疫系统蛋白 Download PDFInfo
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| US7833529B1 (en) | 1999-01-07 | 2010-11-16 | Zymogenetics, Inc. | Methods for inhibiting B lymphocyte proliferation with soluble ztnf4 receptor |
| US20030095967A1 (en) | 1999-01-25 | 2003-05-22 | Mackay Fabienne | BAFF, inhibitors thereof and their use in the modulation of B-cell response and treatment of autoimmune disorders |
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| US6475986B1 (en) | 1999-02-02 | 2002-11-05 | Research Development Foundation | Uses of THANK, a TNF homologue that activates apoptosis |
| EP1860190A3 (en) * | 1999-02-23 | 2008-03-12 | Human Genome Sciences, Inc. | Neutrokine-alpha and neutrokine-alpha splice variants |
| US20030022233A1 (en) | 1999-04-30 | 2003-01-30 | Raymond G. Goodwin | Methods of use of the taci/taci-l interaction |
| AU4986700A (en) | 1999-05-06 | 2000-11-21 | National Jewish Medical And Research Center | Tall-1 nucleic acid molecules, proteins, receptors and methods of use thereof |
| CA2383154C (en) * | 1999-08-17 | 2013-04-30 | Biogen, Inc. | Baff receptor (bcma), an immunoregulatory agent |
| UA74798C2 (uk) * | 1999-10-06 | 2006-02-15 | Байоджен Айдек Ма Інк. | Спосіб лікування раку у ссавця за допомогою поліпептиду, що протидіє взаємодії april з його рецепторами |
| EP1259544B1 (en) | 2000-02-11 | 2011-08-24 | Biogen Idec MA Inc. | Heterologous polypeptide of the tnf family |
| IL150755A0 (en) | 2000-02-16 | 2003-02-12 | Genentech Inc | Uses of agonists and antagonists to modulate activity of tnf-related molecules |
| US20020086018A1 (en) | 2000-05-12 | 2002-07-04 | Theill Lars Eyde | Methods and compositions of matter concerning APRIL/G70, BCMA, BLYS/AGP-3, and TACI |
| KR101155294B1 (ko) | 2000-06-16 | 2013-03-07 | 캠브리지 안티바디 테크놀로지 리미티드 | 면역특이적으로 ＢＬｙＳ에 결합하는 항체 |
| US7220840B2 (en) | 2000-06-16 | 2007-05-22 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to B lymphocyte stimulator protein |
| CA2419661A1 (en) * | 2000-08-15 | 2002-03-07 | Guo-Liang Yu | Neutrokine-alpha and neutrokine-alpha splice variant |
| US20030091565A1 (en) | 2000-08-18 | 2003-05-15 | Beltzer James P. | Binding polypeptides and methods based thereon |
| UA83458C2 (uk) | 2000-09-18 | 2008-07-25 | Байоджен Айдек Ма Інк. | Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf) |
| EP2292655B1 (en) | 2001-05-11 | 2012-03-14 | Amgen SF, LLC | Peptides and related molecules that bind to tall-1 |
| AR035119A1 (es) | 2001-08-16 | 2004-04-14 | Lilly Co Eli | Anticuerpos humanos antagonistas anti-htnfsf13b |
| AU2004233164B2 (en) | 2003-03-28 | 2009-10-08 | Biogen Ma Inc. | Truncated BAFF receptors |
| EP1629001A2 (en) | 2003-06-05 | 2006-03-01 | Genentech, Inc. | Blys antagonists and uses thereof |
| AU2004285455A1 (en) | 2003-10-20 | 2005-05-12 | Biogen Idec Ma Inc. | Therapeutic regimens for BAFF antagonists |
| US20070249530A1 (en) * | 2004-01-29 | 2007-10-25 | Genentech, Inc. | Bcma Polypeptides and Uses Thereof |
| US20060110387A1 (en) | 2004-10-05 | 2006-05-25 | Genentech, Inc. | Method for treating vasculitis |
| EP1814577B1 (en) | 2004-10-13 | 2014-04-23 | The Washington University | Use of baff to treat sepsis |
| AU2005318086B2 (en) | 2004-12-23 | 2011-07-07 | Merck Serono Sa | BCMA polypeptides and uses thereof |
| JP2009507777A (ja) | 2005-08-09 | 2009-02-26 | ザイモジェネティクス，インコーポレイティド | ＴＡＣＩ−Ｉｇ融合分子を用いたＢ細胞性腫瘍の処置方法 |
| US8808696B2 (en) | 2005-08-09 | 2014-08-19 | Ares Trading S.A. | Methods for the treatment and prevention of abnormal cell proliferation using TACI-fusion molecules |
| US9168286B2 (en) | 2005-10-13 | 2015-10-27 | Human Genome Sciences, Inc. | Methods and compositions for use in treatment of patients with autoantibody positive disease |
| MY149159A (en) | 2005-11-15 | 2013-07-31 | Hoffmann La Roche | Method for treating joint damage |
| EP1952150B1 (en) | 2005-11-23 | 2016-12-14 | Genentech, Inc. | Methods and compositions related to b cell assays |
| WO2007123765A2 (en) | 2006-03-31 | 2007-11-01 | Human Genome Sciences Inc. | Neutrokine-alpha and neutrokine-alpha splice variant |
| BRPI0711823A2 (pt) | 2006-05-15 | 2012-01-17 | Ares Trading Sa | métodos para tratamento de doenças auto-imunes com uma molécula de fusão taci-ig |
| WO2010075249A2 (en) | 2008-12-22 | 2010-07-01 | Genentech, Inc. | A method for treating rheumatoid arthritis with b-cell antagonists |
| EP3211094A3 (en) | 2009-09-03 | 2017-11-01 | F. Hoffmann-La Roche AG | Methods for treating, diagnosing, and monitoring rheumatoid arthritis |
| WO2012118750A2 (en) | 2011-02-28 | 2012-09-07 | Genentech, Inc. | Biological markers and methods for predicting response to b-cell antagonists |
| WO2014122144A1 (en) | 2013-02-05 | 2014-08-14 | Engmab Ag | BISPECIFIC ANTIBODIES AGAINST CD3ε AND BCMA |
| US9458246B2 (en) | 2013-03-13 | 2016-10-04 | Amgen Inc. | Proteins specific for BAFF and B7RP1 |
| JOP20140087B1 (ar) | 2013-03-13 | 2021-08-17 | Amgen Inc | بروتينات مخصصة ل baff و b7rp1 وإستخداماتها |
| WO2015155332A1 (en) | 2014-04-11 | 2015-10-15 | Boehringer Ingelheim International Gmbh | Spiro[3h-indole-3,2'-pyrrolidin]-2(1h)-one derivatives and their use as mdm2-p53 inhibitors |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2155103A1 (en) * | 1993-02-03 | 1994-08-18 | Rudolph Lucas | Tnf-alpha muteins and a process for preparing them |
| WO1996040774A1 (en) * | 1995-06-07 | 1996-12-19 | Biogen, Inc. | Complexes of modified lymphotoxins as pharmaceutical preparations |
| ATE302272T1 (de) * | 1996-10-25 | 2005-09-15 | Human Genome Sciences Inc | Neutrokin alpha |
| AU5705898A (en) * | 1996-12-17 | 1998-07-15 | Schering Corporation | Mammalian cell surface antigens; related reagents |
| CA2232743A1 (en) * | 1997-04-02 | 1998-10-02 | Smithkline Beecham Corporation | A tnf homologue, tl5 |
-
1998
- 1998-09-11 EA EA200000311A patent/EA200000311A1/ru unknown
- 1998-09-11 JP JP2000510769A patent/JP2001515711A/ja not_active Withdrawn
- 1998-09-11 BR BR9812433-1A patent/BR9812433A/pt not_active IP Right Cessation
- 1998-09-11 AU AU93152/98A patent/AU9315298A/en not_active Abandoned
- 1998-09-11 PL PL98339740A patent/PL339740A1/xx not_active Application Discontinuation
- 1998-09-11 CN CN98809023A patent/CN1269832A/zh active Pending
- 1998-09-11 EE EEP200000148A patent/EE200000148A/xx unknown
- 1998-09-11 EP EP98946052A patent/EP1012270A2/en not_active Withdrawn
- 1998-09-11 HU HU0004034A patent/HUP0004034A3/hu unknown
- 1998-09-11 CA CA002303424A patent/CA2303424A1/en not_active Abandoned
- 1998-09-11 IL IL13448098A patent/IL134480A0/xx unknown
- 1998-09-11 SK SK353-2000A patent/SK3532000A3/sk unknown
- 1998-09-11 WO PCT/US1998/019037 patent/WO1999012964A2/en not_active Application Discontinuation
- 1998-09-11 TR TR2000/00654T patent/TR200000654T2/xx unknown
- 1998-09-11 KR KR1020007002576A patent/KR20010023892A/ko not_active Application Discontinuation
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2000
- 2000-02-11 IS IS5375A patent/IS5375A/is unknown
- 2000-03-09 NO NO20001240A patent/NO20001240L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| BR9812433A (pt) | 2000-09-26 |
| WO1999012964A3 (en) | 1999-05-27 |
| TR200000654T2 (tr) | 2000-07-21 |
| AU9315298A (en) | 1999-03-29 |
| CA2303424A1 (en) | 1999-03-18 |
| KR20010023892A (ko) | 2001-03-26 |
| NO20001240D0 (no) | 2000-03-09 |
| JP2001515711A (ja) | 2001-09-25 |
| PL339740A1 (en) | 2001-01-02 |
| EE200000148A (et) | 2001-02-15 |
| IL134480A0 (en) | 2001-04-30 |
| WO1999012964A2 (en) | 1999-03-18 |
| HUP0004034A2 (en) | 2001-03-28 |
| EP1012270A2 (en) | 2000-06-28 |
| EA200000311A1 (ru) | 2000-10-30 |
| NO20001240L (no) | 2000-05-10 |
| IS5375A (is) | 2000-02-11 |
| HUP0004034A3 (en) | 2002-08-28 |
| SK3532000A3 (en) | 2001-12-03 |
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