CN1244318C - Wrinkle-eliminating senility-reisting and face-remaining cosmetic additive and its process - Google Patents

Abstract

The present invention mainly relates to a cosmetic for removing wrinkles, resisting senescence and keeping faces, particularly to an additive of the cosmetic for removing wrinkles, resisting senescence and keeping faces and a technology of the additive. The additive of the cosmetic for removing wrinkles, resisting senescence and keeping faces is mainly characterized in that the additive comprises an extraction liquid of eucommia barks and an extraction liquid of sweetvetch roots. The present invention can promote the synthesis of collagen protein; the collagen is a protein whose content is maximum in human bodies and accounts for 1/3 of total protein content in human bodies and 70% of skin net weight. One main aminophenol synthesizing the collagen protein is hydroxyproline. The present invention can make the hydroxyproline enhanced by 1.2 times to promote the synthesis of the collagen protein accounting for 70% of skin and promote cell regeneration. The cosmetic has obvious effect on enhancing skin elasticity and healing chap, contains rich aminophenol and vitamins required by human body cells, and has favorable moistening and wetness-retaining effect. The technology of the present invention makes extracts colorless, tasteless, clear and transparent, and conforms to the requirements of cosmetics.

Description

Removing wrinkle and resisting aging preserve youthful looks cosmetics additive and technology thereof

Technical field:

The present invention relates generally to a kind of removing wrinkle and resisting aging cosmetics of preserving youthful looks, and relates in particular to removing wrinkle and resisting aging the preserve youthful looks additive and the technology thereof of cosmetics.

Background technology:

Along with the raising of people's living standard, also more and more higher to the requirement of quality of life.And because the growth at age, the losing of collagen protein in the skin, the minimizing of human body smegma, the infringement of long-term in addition ultraviolet damage and free radical, people's wrinkle of skin increases, and deepens, and cutis laxa does not have elasticity, and drying is lackluster.If the cosmetics of some chemosynthesis of life-time service very easily cause side effect such as the allergy, inflammation, system poison of skin, domestic in recent years for this reason research worker begins to seek effective ingredient from natural biological, application number is that 00112530.3 patent application discloses the preserve youthful looks additive of natural activity cosmetics of a kind of removing wrinkle and resisting aging, mainly by the extract complex configuration of multiple natural plants such as the Radix Astragali, Radix Bupleuri, Radix Ginseng.Because the composition that adopts is many, technology more complicated for this reason, cost is also than higher.

Summary of the invention:

The objective of the invention is to avoid the deficiencies in the prior art part and a kind of removing wrinkle and resisting aging cosmetics additive of preserving youthful looks is provided.This additive can promote the synthetic of collagen protein, and skin metabolism is accelerated, and has the effect of tangible removing wrinkle and resisting aging.Technology is simple, and cost is low.

Purpose of the present invention can be by realizing by the following technical solutions: a kind of removing wrinkle and resisting aging cosmetics additive of preserving youthful looks, include the extracting solution of the Cortex Eucommiae, and its main feature is the extracting solution that also includes the Radix Hedysari root.

Described removing wrinkle and resisting aging preserves youthful looks that the extracting solution of the cosmetics additive Cortex Eucommiae is 9098% by weight, the extracting solution of Radix Hedysari root is by weight being 2-10%.

The percentage by weight that the present invention adds in cosmetics is 2-10%.Described cosmetics are made of oil phase, water, emulsifying agent.

The technology of the Cortex Eucommiae of additive of the present invention, Radix Hedysari root extracting solution is:

(1). Folium Eucommiae, Radix Hedysari root are cleaned, and add 1: 8-1: 15 times of water boil 1-3 hour after-filtration; Recrement continued to boil 0.5-1.5 hour, filtered; Twice filtrate mixed;

(2). distillating filtering liquid, temperature 90-110 ℃, pressure is normal pressure;

(3). simmer down to contains crude drug in whole 1g/ml, and ℃ preservation is stand-by in (10)-0.

It is as follows that this additive contains the needed peculiar composition of beauty treatment by analysis:

1. contain peculiar compositions such as aucubin and chlorogenic acid.

Through spectrophotometric and chromatography, the main chemical compositions in this additive has aucubin (aucubin), chlorogenic acid (chlorogenic acid), and content is respectively 2.6% and 3.1%.The former can not only promote the synthetic of collagen protein, and proves the effect that obvious promotion wound healing is arranged clinically.Chlorogenic acid then has the function of anti-inflammation, and various bacteria such as escherichia coli, pseudomonas aeruginosa, golden yellow staphylococcus are had inhibitory action, is cleaning skin and the dermopathic desirable composition of treatment.Can also promote end density lipoprotein to reduce or the metabolism increase, reach the effect that prolongs cell survival and improve looks.

Also have a certain amount of (+)-Pinoresinol diglucoside in addition, it can promote the external perihaemal canal expansion, accelerates the microcirculation of skin, strengthens skin metabolism and increases ruddy.

Above chemical compound also has stronger osmosis, can arrive deep skin rapidly.This also is to seek for it in the cosmetics.

2. contain aminoacid.

Amino acid content is as table in the employing automatic amino acid analyzer working sample

Various amino acid contents (%) in table 1 sample

* be essential amino acid.

By the table in as seen, containing abundant amino acid in this additive is the extraordinary nutrient source of Skin Cell.Wherein essential amino acid (needed by human but human body can not synthesize again, can only outerly help additional aminoacid) is considerable especially.Especially relevant with forming ' collagen ' glycine, proline and lysine are very outstanding.

3. contain trace element.

Through the constant volume analysis simultaneously of plasma-speetrometer multielement, measure and contain the essential a great number of elements of human skin cell in this additive, particularly protect the manganese, zinc, copper, selenium, chromium, molybdenum of cell etc.

Micronutrient levels in table 2 sample (mg/kg)

Element	As B Ca Co Cr Cu Fe Mg Mn Mo P Pb Se Zn Na K
		Sample	0.00 0.19 3.87 0.65 0.32 23.68 49.44 17.78 12.31 5.91 18.20 0.00 0.29 1.38 127.87 104

The antioxidation of Cu, Zn, Mn, Se.The aging of Skin Cell is directly related greater than removing with oxygen production, because active oxygen superfluous in the cell can bring out a series of free radical chain reactionses, start peroxidation of membrane lipids, thereby the structure and the function of disrupting biofilm and other biomacromolecule, and then cause skin sclerosis, coarse, wrinkling, make skin aging.The intracellular reactive oxygen scavenger, as excessive active oxygen in the superoxide dismutase scavenger cells under normal circumstances such as (SOD), the prothetic group of these enzymes mainly is a little ions, as SOD, Zn-SOD, Cu-SOD, Mn-SOD is arranged.The prothetic group Se of glutathione peroxidase.As seen the acquisition of trace element such as Cu, Zn, Mn, Se, finger have influence on this zymoid synthetic and effect.Contain chlorogenic acid, geniposidic acid and caryophyllin bioside in addition in this additive, these compositions all have stronger antioxidation, superoxide anion (O in the serum ₂) clearance rate reaches 70%; Reduce lipid peroxide (LPO) effect and reach 64%.This is the effect that general ingredient is difficult to reach.

Trace element also exists substantial connection with human cell's immunity, metabolism and aging.Zn also determines and affects in the cell enzymatic activity more than 80 kinds except that very strong antioxidation is arranged, and can protect the sulfydryl on the cell membrane and regulate adenosine triphosphate and reach protective action.Se also has and prevents aging and anticancer effect.In addition, Zn, Se etc. are the antidote of heavy metal lead (Pb), hydrargyrum (Hg), cadmium (Cd) and so on still, to more and with the heavy metal side effect, skin protection and treatment double effects are arranged with the chemosynthesis cosmetics.Cu can absorb through skin and play antiinflammatory action in the blood, and biological complex also can be eliminated superoxides.Trace element such as Cr, Cu can also reduce the interior insulin of cell and content of cholesterol prevents sclerosis of blood vessels, promotes microcirculation, makes the skin delicacy ruddy.

4. contain little element of giving birth to.

Vitamin adopts high performance liquid chromatograph to measure, and the result is as follows:

The content of vitamin (mg/100g) in table 3 sample

V _CBe not only generally acknowledged antioxidant vitamins, and it can participate in carboxylation reaction, help the synthetic of hydroxyproline, promote the metabolism of collagen.

V _B2Participate in metabolism, particularly protein metabolism, particularly protein metabolism as the flavo-enzyme prothetic group.Lack V _B2The time, amino acid whose excretion increases, and the glutathione reductase vitality descends, and directly influences antioxidation.

V _EHave the strong anti-oxidation ability and prevent Oxidation of Fat and Oils.V is arranged in unsaturated fatty acid _ECan improve its stability and nutritive value greatly.V _ECan also promote skin metabolism, prevent that xerosis cutis is coarse, strengthen skin absorbs.V _EUnder the effect of acetic acid, generate in " vitamin acetic acid fat ", and the viscosity of vitamin E acetic acid fat is low, to the osmosis of skin than V _EStronger, and physiologic effect and V _EIdentical.

The present invention is through acute toxicity test, and result＞50ml/kg confirms totally nontoxic.

Clinical report confirms that canthus wrinkle is tested 68 examples, and 56 routine effects are remarkable, accounts for 82%, 12 example and takes a turn for the better, and accounts for 18%.Skin is obviously delicate, elasticity obviously increases, and wrinkle obviously shoals.Observe the effect of chapping obviously simultaneously, this also is to promote cell regeneration, can work the clinical response the most intuitively that changes the skin effect.

The invention has the beneficial effects as follows:

1. can promote the synthetic of collagen protein, collagen is the maximum protein of people's in-vivo content, accounts for 1/3 of human body total protein content, 70% of skin dry weight.One of synthetic proteic main aminoacid of collagen is hydroxyproline, and the present invention can make hydroxyproline improve 1.2 times.Can promote to account for the collagen protein synthesis of skin 70% for this reason, promote cell regeneration.To strengthening skin elasticity and chapping to heal positive effect is arranged.

2. contain abundant human body cell essential amino acid and vitamin, have good moist, moistening effect.

3. contain manganese Mn, zinc Zn, copper Cu, selenium Se, VE, the VC of abundant protection cell, have stronger oxidation resistance, prevent cell senescence, eliminate pigmentation, reduce wrinkle and generate.

4. technology of the present invention makes extract colourless, tasteless, as clear as crystal, meets the requirement of cosmetics.

The specific embodiment:

Be described in further detail below in conjunction with most preferred embodiment:

Embodiment 1: a kind of removing wrinkle and resisting aging cosmetics additive of preserving youthful looks.

Get 95 parts of Cortex Eucommiae extracting solution by weight, get 5 parts of mixing of extracting solution of Radix Hedysari root.

Embodiment 2: the preserve youthful looks Cortex Eucommiae of cosmetics additive, the technology of Radix Hedysari root extracting solution of removing wrinkle and resisting aging is:

(1). Folium Eucommiae, Radix Hedysari root are cleaned, and add 2 hours after-filtration of ten times of water boils; Recrement continued to boil 1 hour, filtered; Twice filtrate mixed;

(2). distillating filtering liquid, 100 ℃ of temperature, pressure is normal pressure;

(3). simmer down to contains crude drug in whole 1g/ml, and ℃ preservation is stand-by in (10)-0.

Application examples:

A kind of removing wrinkle and resisting aging the preserve youthful looks prescription and the technology (percentage by weight) of cosmetics: get oil phase 20%, water 70%, additive 10% of the present invention, and wetting agent, UV absorbent, penetrating agent, subcutaneous tissue promoter, antiseptic, essence are an amount of, the deionized water surplus.

Oil phase and water are heated to 70 ℃ mix stirring, circulation is cooled to 50 ℃ and adds additives, shuts down discharging, leaves standstill room temperature and check, pack for 43 ℃.

Claims (4)

1. removing wrinkle and resisting aging cosmetics additive of preserving youthful looks includes the extracting solution of the Cortex Eucommiae, it is characterized in that also including the extracting solution of Radix Hedysari root, and its extracting solution is by weight being 2-10%; The extracting solution of the Cortex Eucommiae is 90-98% by weight.

2. the removing wrinkle and resisting aging as claimed in claim 1 cosmetics additive of preserving youthful looks is characterized in that the percentage by weight that adds is 2-10% in cosmetics.

3. the removing wrinkle and resisting aging as claimed in claim 3 cosmetics additive of preserving youthful looks is characterized in that described cosmetics are made of oil phase, water, emulsifying agent.

4. be used for removing wrinkle and resisting aging as claimed in claim 1 the preserve youthful looks Cortex Eucommiae of cosmetics additive, the preparation method of Radix Hedysari root extracting solution, it is characterized in that:

(1). Folium Eucommiae, Radix Hedysari root are cleaned, and add 1: 8-1: 15 times of water boil 1-3 hour after-filtration; Recrement continued to boil 0.5-1.5 hour, filtered; Twice filtrate mixed;

(2). distillating filtering liquid, temperature 90-110 ℃, pressure is normal pressure;

(3). simmer down to contains crude drug in whole 1g/ml, and ℃ preservation is stand-by in (10)-0.