CN110680764A - Essence containing agaricus bisporus extract and preparation method thereof - Google Patents

Essence containing agaricus bisporus extract and preparation method thereof Download PDF

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CN110680764A
CN110680764A CN201911052258.5A CN201911052258A CN110680764A CN 110680764 A CN110680764 A CN 110680764A CN 201911052258 A CN201911052258 A CN 201911052258A CN 110680764 A CN110680764 A CN 110680764A
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agaricus bisporus
extract
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张惠生
黄飞
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Hunan Woman Spring Cosmetology Co Ltd
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Hunan Woman Spring Cosmetology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34Alcohols
    • A61K8/345Alcohols containing more than one hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42Amides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/673Vitamin B group
    • A61K8/675Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59Mixtures
    • A61K2800/592Mixtures of compounds complementing their respective functions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Dermatology (AREA)
  • Botany (AREA)
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  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention provides an essence containing agaricus bisporus extract and a preparation method thereof, wherein the essence comprises the following components in parts by weight: 6-10 parts of agaricus bisporus extract, 1-3 parts of nicotinamide, 0.5-2.5 parts of panthenol, 2-5 parts of humectant, 0.01-0.05 part of preservative and 30-50 parts of water. According to the essence prepared by the invention, the agaricus bisporus extract, the nicotinamide and the panthenol are combined, the dosage and the proportion of each raw material are controlled, the synergistic effect of the physicochemical properties of the agaricus bisporus extract is improved, the rapid deep absorption of active ingredients is realized, and the essence has better effects of resisting oxidation, keeping moisture high, tightening skin and resisting aging.

Description

Essence containing agaricus bisporus extract and preparation method thereof
Technical Field
The invention relates to the technical field of cosmetics, and particularly relates to essence containing agaricus bisporus extract and a preparation method thereof.
Background
Agaricus bisporus (also called white mushroom, agaricus bisporus) and agaricus bisporus, which belongs to the edible and medicinal fungi of grass saprophytic and medium-low temperature type. The agaricus bisporus contains rich amino acid, unsaturated fatty acid and trace elements and has obvious anti-fatigue effect; with the continuous and deep research of large fungi, polysaccharide extraction is carried out by taking agaricus bisporus sporocarp as a raw material, and free radicals such as various OH, DPPH, superoxide anions and the like can be removed by agaricus bisporus polysaccharide, so that the agaricus bisporus polysaccharide can be used as a natural antioxidant; active substances such as high-activity neuraminidase and ergothione can be separated from the agaricus bisporus extract, so that the agaricus bisporus can be applied to the fields of food, medicine and cosmetics.
However, fresh agaricus bisporus bodies are easy to brown, oxidation resistance of agaricus bisporus extracts is greatly influenced, and when agaricus bisporus is used as a raw material in a skin care product, active ingredients of the agaricus bisporus often only stay on the surface of skin and cannot be effectively absorbed deeply, and the agaricus bisporus is applied to daily moisturizing skin care varieties, and most of the agaricus bisporus usually only plays a moisturizing role, so that the agaricus bisporus needs to be further developed in the skin care essence to obtain the essence which has high oxidation resistance and moisturizing capability and can be rapidly absorbed deeply.
Disclosure of Invention
In view of the above, the invention provides the essence containing the agaricus bisporus extract and the preparation method thereof, and the prepared essence realizes rapid deep absorption and has better effects of resisting oxidation, preserving moisture, tightening skin and resisting aging.
The technical scheme of the invention is realized as follows:
the invention provides an essence containing agaricus bisporus extract, which comprises the following components in parts by weight: 6-10 parts of agaricus bisporus extract, 1-3 parts of nicotinamide, 0.5-2.5 parts of panthenol, 2-5 parts of humectant, 0.01-0.05 part of preservative and 30-50 parts of water.
Further, the agaricus bisporus extract is an agaricus bisporus submerged fermentation extract obtained by performing crude extraction on agaricus bisporus by using a water extraction method and performing ultraviolet irradiation submerged fermentation on the agaricus bisporus extract.
Further, the preparation method of the agaricus bisporus crude extract comprises the following steps: cutting fresh agaricus bisporus sporocarp, adding water according to the proportion of 1 (50-60) to homogenate, extracting homogenate liquid in a boiling water bath for 1-2 h at 8000r/min, centrifuging for 15min, collecting supernatant, concentrating and fixing the volume to obtain agaricus bisporus crude extract.
Further, the preparation method of the agaricus bisporus extract comprises the following steps: uniformly mixing the agaricus bisporus crude extract, a carbon source and yeast seed bacterial liquid which is subjected to 15-20 w ultraviolet short-time irradiation treatment for 30-60 min according to the mass ratio of 1:0.5:0.1, sending the mixture into a fermentation chamber, fermenting for 8-10 days at 23-28 ℃, periodically adding the carbon source and adjusting the pH value to 5.2-6.2, collecting a fermentation product after fermentation is finished, collecting a supernatant, filtering, concentrating and fixing the volume to obtain the agaricus bisporus deep layer fermentation extract. The activity of a submerged fermentation product of active substances in the agaricus bisporus crude extract is higher, and the agaricus bisporus extract obtained by combining water leaching and submerged fermentation extraction is combined with nicotinamide, so that the agaricus bisporus extract has a good antibacterial effect, is beneficial to deep absorption of skin, and improves the antioxidant and moisturizing effects.
Further, the traditional Chinese medicine composition further comprises 0.2-0.5 part by weight of an absorption-aiding traditional Chinese medicine extract, wherein the absorption-aiding traditional Chinese medicine extract is a mixed traditional Chinese medicine extract which is obtained by mixing astragalus mongholicus and folium cortex eucommiae according to a mass ratio of 1 (3-5), adding water for leaching at room temperature, and concentrating to a constant volume. The combination of the mixed traditional Chinese medicine extract of the astragalus and the eucommia leaves and the nicotinamide further improves the microcirculation of the skin surface and increases the rapid deep absorption of the effective components of the agaricus bisporus extract.
Further, the humectant is one or more of propylene glycol, hyaluronic acid, sorbitol and seaweed extract; the preservative is methyl chloro isothiazolinone.
Further, the paint comprises the following components in parts by weight: 6-8 parts of agaricus bisporus extract, 2-3 parts of nicotinamide, 0.5-1.5 parts of panthenol, 2-3 parts of propylene glycol, 0.2-0.3 part of traditional Chinese medicine extract for absorption assistance, 0.01-0.02 part of methyl chloroisothiazolinone and 35-50 parts of water.
A preparation method of essence containing agaricus bisporus extract comprises the following steps:
(1) adding the raw materials of nicotinamide, humectant and water into an emulsifying pot according to the proportion, heating to 75-85 ℃, stirring at a constant temperature for 10-20 min, wherein the stirring speed is 1300-1500 r/min;
(2) cooling to 45-50 ℃, slowly and sequentially adding panthenol and the agaricus bisporus extract, and uniformly stirring at the stirring speed of 800-1000 r/min;
(3) cooling to less than or equal to 40 ℃, adding a preservative, continuously cooling to 36-38 ℃, uniformly stirring and finely stirring at the stirring speed of 550-600 r/min, and standing for 3-5 hours;
(4) and after the inspection is qualified, filtering and discharging the materials by using a 800-120-mesh sieve to obtain the essence containing the agaricus bisporus extract.
Further, in the step (2), after the temperature is reduced to 45 ℃, the absorption-assisting traditional Chinese medicine extract is added and stirred uniformly, and the stirring speed is 850 r/min.
Further explaining, in the step (3), when the temperature is reduced to 30-35 ℃, stopping stirring and standing.
Compared with the prior art, the invention has the beneficial effects that: the essence containing the agaricus bisporus extract is mainly characterized in that the agaricus bisporus extract, the nicotinamide and the panthenol are combined, the dosage and the proportion of the raw materials are controlled, the synergistic effect of the physicochemical properties of the agaricus bisporus extract is improved, the active ingredients of the agaricus bisporus extract are enhanced to deeply permeate to directly reach the inner layer of the skin, and the active ingredients are maintained to stably exist under the combined action of the panthenol and the nicotinamide, the skin microcirculation is promoted, the deep absorption of the skin is accelerated, and the effects of resisting oxidation, preserving moisture, inhibiting pigment deposition and the like are fundamentally exerted. Especially, the agaricus bisporus extract obtained by combining water extraction and submerged fermentation extraction is combined with nicotinamide, so that the nourishing and permeating effects of skin on natural plant essence can be obviously enhanced, the rapid deep absorption of effective components is promoted, the effective components directly participate in the metabolism of cells, the effects of high oxidation resistance and high moisture retention are achieved, and the synergistic effect of enhancing skin repair is achieved by combining panthenol; the product is comfortable after use, can be absorbed quickly, is not greasy, and has good effects of whitening skin, keeping moisture, and resisting oxidation and aging.
Detailed Description
In order to better understand the technical content of the invention, specific examples are provided below to further illustrate the invention.
The experimental methods used in the examples of the present invention are all conventional methods unless otherwise specified.
The materials, reagents and the like used in the examples of the present invention can be obtained commercially without specific description.
Example 1-an essence containing agaricus bisporus extract, comprising the following components in parts by weight: 10 parts of agaricus bisporus extract, 1 part of nicotinamide, 2.5 parts of panthenol, 5 parts of humectant, 0.05 part of preservative and 30 parts of water.
The humectant is propylene glycol; the preservative is methyl chloro isothiazolinone.
Example 2-an essence containing agaricus bisporus extract, comprising the following components in parts by weight: 6 parts of agaricus bisporus extract, 3 parts of nicotinamide, 0.5 part of panthenol, 2 parts of humectant, 0.2 part of absorption-aiding traditional Chinese medicine extract, 0.01 part of preservative and 35 parts of water.
The absorption-aiding traditional Chinese medicine extract is a mixed traditional Chinese medicine extract which is prepared by mixing astragalus and eucommia leaves according to the mass ratio of 1:3, adding water for leaching at room temperature, and concentrating to a constant volume.
The humectant is 1 part of sorbitol and 1 part of algae extract; the preservative is methyl chloro isothiazolinone.
The agaricus bisporus extract is an agaricus bisporus submerged fermentation extract obtained by performing crude extraction on agaricus bisporus by adopting a water extraction method and then performing ultraviolet irradiation submerged fermentation, and the specific preparation method is as follows:
(1) cutting fresh Agaricus bisporus fruiting body, adding water at a ratio of 1:50 for homogenizing, extracting the homogenate in boiling water bath for 1h at 8000r/min, centrifuging for 15min, collecting supernatant, concentrating and diluting to desired volume to obtain Agaricus bisporus crude extract;
(2) uniformly mixing the agaricus bisporus crude extract, a carbon source and yeast seed bacterium liquid which is subjected to 15w ultraviolet short-time irradiation treatment for 30min according to the mass ratio of 1:0.5:0.1, sending the mixture into a fermentation chamber to ferment for 8 days at 23-28 ℃, periodically adding the carbon source and adjusting the pH value to 5.2, wherein the carbon source is one or more of glucose, fructose, corn flour, sweet potato flour and soluble starch: and after the fermentation is finished, collecting the fermentation product, collecting the supernatant, filtering, concentrating to a constant volume to obtain the agaricus bisporus submerged fermentation extract.
Example 3-an essence containing agaricus bisporus extract, comprising the following components in parts by weight: 8 parts of agaricus bisporus extract, 2 parts of nicotinamide, 1.5 parts of panthenol, 3 parts of humectant, 0.3 part of absorption-aiding traditional Chinese medicine extract, 0.02 part of preservative and 50 parts of water.
The absorption-aiding traditional Chinese medicine extract is a mixed traditional Chinese medicine extract which is prepared by mixing astragalus and eucommia leaves according to the mass ratio of 1:5, adding water for leaching at room temperature, and concentrating to a constant volume.
The humectant comprises 1 part of propylene glycol, 1 part of hyaluronic acid and 1 part of sorbitol; the preservative is methyl chloro isothiazolinone.
The agaricus bisporus extract is an agaricus bisporus submerged fermentation extract obtained by performing crude extraction on agaricus bisporus by adopting a water extraction method and then performing ultraviolet irradiation submerged fermentation; the preparation method comprises the following steps:
(1) cutting fresh Agaricus bisporus fruiting body, adding water at a ratio of 1:60 for homogenizing, extracting the homogenate in boiling water bath for 2h at 8000r/min, centrifuging for 15min, collecting supernatant, concentrating and diluting to desired volume to obtain Agaricus bisporus crude extract;
(2) uniformly mixing the agaricus bisporus crude extract, a carbon source and yeast seed bacterium liquid subjected to 20w ultraviolet short-time irradiation treatment for 60min according to the mass ratio of 1:0.5:0.1, sending the mixture into a fermentation chamber for fermentation at 23-28 ℃ for 10 days, periodically adding the carbon source and adjusting the pH value to 6.2, wherein the carbon source is one or more of glucose, fructose, corn flour, sweet potato flour and soluble starch: and after the fermentation is finished, collecting the fermentation product, collecting the supernatant, filtering, concentrating to a constant volume to obtain the agaricus bisporus submerged fermentation extract.
Example 4-a method for preparing an essence containing agaricus bisporus extract, comprising the steps of:
(1) according to the formula and the proportion of the essence containing the agaricus bisporus extract in the embodiment 1, the raw materials of nicotinamide, humectant and water are put into an emulsifying pot, the temperature is raised to 75 ℃, the mixture is stirred for 20min at a constant temperature, and the stirring speed is 1300 r/min;
(2) cooling to 45 deg.C, slowly adding panthenol and Agaricus bisporus extract in sequence, and stirring at 800 r/min;
(3) cooling to less than or equal to 40 ℃, adding the preservative, continuously cooling to 36 ℃, uniformly stirring at 550r/min, and standing for 3 hours;
(4) and after the inspection is qualified, filtering and discharging the materials by using a 120-mesh sieve to obtain the essence containing the agaricus bisporus extract.
Example 5-a method for preparing an essence containing agaricus bisporus extract, comprising the steps of:
(1) according to the formula and the proportion of the essence containing the agaricus bisporus extract in the embodiment 3, the raw materials of nicotinamide, humectant and water are put into an emulsifying pot, the temperature is raised to 85 ℃, the constant temperature stirring is carried out for 10min, and the stirring speed is 1500 r/min;
(2) cooling to 50 deg.C, slowly adding panthenol and Agaricus bisporus extract in sequence, and stirring at 1000 r/min; cooling to 45 deg.C, adding the absorption-promoting Chinese medicinal extract, and stirring at 850 r/min;
(3) cooling to less than or equal to 40 ℃, adding the preservative, continuously cooling to 38 ℃, uniformly stirring at the speed of 600r/min, stopping stirring when the temperature is reduced to 30 ℃, and standing for 5 hours;
(4) and after the inspection is qualified, filtering and discharging the materials by using a 100-mesh sieve to obtain the essence containing the agaricus bisporus extract.
Comparative example 1-essence containing agaricus bisporus extract according to example 3, except that the ratio of the agaricus bisporus extract to niacinamide by weight is 15: 2, the rest is the same as example 3.
Comparative example 2-essence containing agaricus bisporus extract according to example 3, except that the agaricus bisporus extract is a combined agaricus bisporus extract obtained by crude extraction of agaricus bisporus by water extraction and then ethanol extraction, and the rest is the same as example 3.
Comparative example 3-essence containing agaricus bisporus extract according to example 3, except that agaricus bisporus crude extract, a carbon source and yeast seed bacterial liquid treated for not less than 1 hour by ultraviolet irradiation are uniformly mixed according to a mass ratio of 1:0.5:0.1, and the rest is the same as example 3.
Comparative example 4-essence containing agaricus bisporus extract according to example 3, except that the absorption-assisting traditional Chinese medicine extract is prepared by mixing astragalus membranaceus and folium cortex eucommiae according to a mass ratio of 1:6, and the rest is the same as example 3.
Comparative example 5-preparation method of essence containing agaricus bisporus extract according to example 5, except that the absorption-assisting herbal extract is added at a temperature of > 45 c in the step (2), and the remaining steps are the same as example 5.
The essences obtained in the above examples 1 to 5 and comparative examples 1 to 5 were subjected to oxidation resistance detection using the hydroxyl radical scavenging rate as an index, and to a moisturizing effect test.
(1) Taking 2mL of the substance with the concentration of 1.00X 102Salicylic acid-ethanol solution at mol/L, FeS04Adding the solution and the sample solution to be detected into the same test tube with a plug, and then adding 2mL of substance with the concentration of 8.80X 102mol/L of H202Shaking the solution evenly, starting the reaction, reacting in water bath at 37 ℃ for 30min, and measuring the absorbance A at 510nm1(ii) a Absorbance A was measured by substituting 2mL of pure water for salicylic acid solution2: absorbance A was measured by substituting 2mL of pure water for the sample solution0. The clearance P is calculated according to the formula:
P=[1-(A1-A2)/A0]×100%。
(2) the moisture retention after 120min = (moisture content of skin after using essence-moisture content of skin before using essence)/moisture content of skin before using essence × 100, and the results are shown in the following table:
Figure BDA0002255613140000061
Figure BDA0002255613140000071
as can be seen from the above table, the hydroxyl radical removal rate and the moisture retention rate of the essences of examples 2 and 3 and example 5 are significantly improved, while in comparative examples 1 to 4, the ratio of the mushroom extract to the nicotinamide, the agaricus bisporus extract extracted by different methods, and other factors are changed, and the oxidation resistance and the moisture retention of the essences are greatly affected.
Skin sensory evaluation tests were performed on the essences obtained in examples 1 to 5 and comparative examples 1 to 5, and 100 persons in skin were 20 to 30 years old who had good skin conditions. Sensory evaluation criteria of the essence are shown in table 1:
sensory evaluation total score is appearance × 0.1+ moisture retention × 0.3+ wrinkle resistance × 0.3+ skin feel × 0.3
Figure BDA0002255613140000072
The results of sensory evaluation of the serum are shown in the following table:
Figure BDA0002255613140000073
Figure BDA0002255613140000081
as can be seen from the above table, the essences of examples 2, 3 and 5 have high sensory evaluation total score, good moisture retention, good wrinkle resistance, and quick and fresh skin feel after use. And performing stability and safety experiments on the essence, namely keeping the temperature at 48 ℃ or-48 ℃ for 24-48 h, and recovering the room temperature without layering and precipitation phenomena; the phenomena of erythema, diagnosis and edema do not occur after the use.
The above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that fall within the spirit and principle of the present invention are intended to be included therein.

Claims (10)

1. An essence containing agaricus bisporus extract is characterized in that: the paint comprises the following components in parts by weight: 6-10 parts of agaricus bisporus extract, 1-3 parts of nicotinamide, 0.5-2.5 parts of panthenol, 2-5 parts of humectant, 0.01-0.05 part of preservative and 30-50 parts of water.
2. The essence containing agaricus bisporus extract according to claim 1, wherein: the agaricus bisporus extract is an agaricus bisporus submerged fermentation extract obtained by performing crude extraction on agaricus bisporus by adopting a water extraction method and performing ultraviolet irradiation submerged fermentation.
3. The essence containing agaricus bisporus extract according to claim 2, wherein: the preparation method of the agaricus bisporus crude extract comprises the following steps:
cutting fresh agaricus bisporus sporocarp, adding water according to the proportion of 1 (50-60) to homogenate, extracting homogenate liquid in a boiling water bath for 1-2 h at 8000r/min, centrifuging for 15min, collecting supernatant, concentrating and fixing the volume to obtain agaricus bisporus crude extract.
4. The essence containing agaricus bisporus extract according to claim 3, wherein: the preparation method of the agaricus bisporus extract comprises the following steps:
uniformly mixing the agaricus bisporus crude extract, a carbon source and yeast seed bacterial liquid which is subjected to 15-20 w ultraviolet short-time irradiation treatment for 30-60 min according to the mass ratio of 1:0.5:0.1, sending the mixture into a fermentation chamber, fermenting for 8-10 days at 23-28 ℃, periodically adding the carbon source and adjusting the pH value to 5.2-6.2, collecting a fermentation product after fermentation is finished, collecting a supernatant, filtering, concentrating and fixing the volume to obtain the agaricus bisporus deep layer fermentation extract.
5. The essence containing agaricus bisporus extract according to claim 1, wherein: the traditional Chinese medicine composition is characterized by also comprising 0.2-0.5 part by weight of an absorption-aiding traditional Chinese medicine extract, wherein the absorption-aiding traditional Chinese medicine extract is a mixed traditional Chinese medicine extract obtained by mixing astragalus mongholicus and folium cortex eucommiae according to a mass ratio of 1 (3-5), adding water for leaching at room temperature, and concentrating to a constant volume.
6. The essence containing agaricus bisporus extract according to claim 5, wherein: the humectant is any one or more of propylene glycol, hyaluronic acid, sorbitol and seaweed extract; the preservative is methyl chloro isothiazolinone.
7. The method for preparing essence containing agaricus bisporus extract according to claim 6, wherein: the paint comprises the following components in parts by weight: 6-8 parts of agaricus bisporus extract, 2-3 parts of nicotinamide, 0.5-1.5 parts of panthenol, 2-3 parts of propylene glycol, 0.2-0.3 part of traditional Chinese medicine extract for absorption assistance, 0.01-0.02 part of methyl chloroisothiazolinone and 35-50 parts of water.
8. A method for preparing the essence containing Agaricus bisporus extract as claimed in any one of claims 1 to 7, wherein: the method comprises the following steps:
(1) adding the raw materials of nicotinamide, humectant and water into an emulsifying pot according to the proportion, heating to 75-85 ℃, stirring at a constant temperature for 10-20 min, wherein the stirring speed is 1300-1500 r/min;
(2) cooling to 45-50 ℃, slowly and sequentially adding panthenol and the agaricus bisporus extract, and uniformly stirring at the stirring speed of 800-1000 r/min;
(3) cooling to less than or equal to 40 ℃, adding a preservative, continuously cooling to 36-38 ℃, uniformly stirring and finely stirring at the stirring speed of 550-600 r/min, and standing for 3-5 hours;
(4) and after the inspection is qualified, filtering and discharging the materials by using a 800-120-mesh sieve to obtain the essence containing the agaricus bisporus extract.
9. The method for preparing essence containing agaricus bisporus extract according to claim 8, wherein: in the step (2), after the temperature is reduced to 45 ℃, the absorption-assisting traditional Chinese medicine extract is added and stirred uniformly, and the stirring speed is 850 r/min.
10. The method for preparing essence containing agaricus bisporus extract according to claim 8, wherein: and (4) stopping stirring and standing when the temperature is reduced to 30-35 ℃ in the step (3).
CN201911052258.5A 2019-10-31 2019-10-31 Essence containing agaricus bisporus extract and preparation method thereof Pending CN110680764A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111588671A (en) * 2020-06-19 2020-08-28 广州科缇生物科技有限公司 Composition with oil control and convergence effects, cosmetic and application of composition

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1535674A (en) * 2003-04-11 2004-10-13 甘肃农业大学 Wrinkle-eliminating senility-reisting and face-remaining cosmetic additive and its process
CN101352406A (en) * 2008-09-12 2009-01-28 北京工商大学 Agaricus bisporus extract and obtaining method and use thereof
CN106344429A (en) * 2016-09-29 2017-01-25 西北农林科技大学 Flammulina velutipes essence and preparation method thereof
CN106701405A (en) * 2016-11-30 2017-05-24 佛山市芊茹化妆品有限公司 Anti-aging grapefruit health care fruit wine and application thereof in cosmetics
CN107412077A (en) * 2017-09-05 2017-12-01 安徽华健生物科技有限公司 It is a kind of it is sun-proof repair skin olive growing leaves it is ultraviolet stress submerged fermentation extract preparation method

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1535674A (en) * 2003-04-11 2004-10-13 甘肃农业大学 Wrinkle-eliminating senility-reisting and face-remaining cosmetic additive and its process
CN101352406A (en) * 2008-09-12 2009-01-28 北京工商大学 Agaricus bisporus extract and obtaining method and use thereof
CN106344429A (en) * 2016-09-29 2017-01-25 西北农林科技大学 Flammulina velutipes essence and preparation method thereof
CN106701405A (en) * 2016-11-30 2017-05-24 佛山市芊茹化妆品有限公司 Anti-aging grapefruit health care fruit wine and application thereof in cosmetics
CN107412077A (en) * 2017-09-05 2017-12-01 安徽华健生物科技有限公司 It is a kind of it is sun-proof repair skin olive growing leaves it is ultraviolet stress submerged fermentation extract preparation method

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
海南女人春天美容有限公司: "女人春天青春凝时精华液", 《国产非特殊用途化妆品备案服务平台 HTTP://FTBA.NMPA.GOV.CN:8181/FTBAN/FW.JSP》 *
王建新: "《化妆品植物原料大全》", 30 June 2012 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111588671A (en) * 2020-06-19 2020-08-28 广州科缇生物科技有限公司 Composition with oil control and convergence effects, cosmetic and application of composition

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