CN120992960A - 诊断及监测伴有坏死过程或与坏死过程相关的对象的疾病或病症的方法 - Google Patents
诊断及监测伴有坏死过程或与坏死过程相关的对象的疾病或病症的方法Info
- Publication number
- CN120992960A CN120992960A CN202511191873.XA CN202511191873A CN120992960A CN 120992960 A CN120992960 A CN 120992960A CN 202511191873 A CN202511191873 A CN 202511191873A CN 120992960 A CN120992960 A CN 120992960A
- Authority
- CN
- China
- Prior art keywords
- dpp3
- disease
- antibody
- diagnosing
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- Health & Medical Sciences (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16166476 | 2016-04-21 | ||
| EP16166476.8 | 2016-04-21 | ||
| PCT/EP2017/059377 WO2017182561A1 (en) | 2016-04-21 | 2017-04-20 | Methods for determining dpp3 and therapeutic methods |
| CN201780039077.1A CN110168372A (zh) | 2016-04-21 | 2017-04-20 | 用于确定dpp3的方法和治疗方法 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201780039077.1A Division CN110168372A (zh) | 2016-04-21 | 2017-04-20 | 用于确定dpp3的方法和治疗方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN120992960A true CN120992960A (zh) | 2025-11-21 |
Family
ID=56014788
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202511191873.XA Pending CN120992960A (zh) | 2016-04-21 | 2017-04-20 | 诊断及监测伴有坏死过程或与坏死过程相关的对象的疾病或病症的方法 |
| CN202510254123.6A Pending CN120093910A (zh) | 2016-04-21 | 2017-04-20 | Dpp3活性抑制剂、包含其的药物组合物及其用途 |
| CN201780039077.1A Pending CN110168372A (zh) | 2016-04-21 | 2017-04-20 | 用于确定dpp3的方法和治疗方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202510254123.6A Pending CN120093910A (zh) | 2016-04-21 | 2017-04-20 | Dpp3活性抑制剂、包含其的药物组合物及其用途 |
| CN201780039077.1A Pending CN110168372A (zh) | 2016-04-21 | 2017-04-20 | 用于确定dpp3的方法和治疗方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20190145981A1 (enExample) |
| EP (5) | EP3854817A1 (enExample) |
| JP (4) | JP2019520550A (enExample) |
| KR (3) | KR102886863B1 (enExample) |
| CN (3) | CN120992960A (enExample) |
| AU (2) | AU2017252212B2 (enExample) |
| BR (1) | BR112018071583A2 (enExample) |
| CA (1) | CA3021252A1 (enExample) |
| CH (1) | CH713803B1 (enExample) |
| DE (1) | DE112017002105T5 (enExample) |
| IL (1) | IL262472B2 (enExample) |
| MX (3) | MX2018012856A (enExample) |
| MY (1) | MY200300A (enExample) |
| SG (1) | SG11201809252YA (enExample) |
| WO (1) | WO2017182561A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MY200300A (en) * | 2016-04-21 | 2023-12-19 | 4TEEN4 Pharmaceuticals GmbH | Methods for determining dpp3 and therapeutic methods |
| KR102835427B1 (ko) * | 2017-10-25 | 2025-07-21 | 4틴4 파마슈티컬스 게엠베하 | 특이적 dpp3-에피토프에 대하여 지시되고 이에 결합하는 dpp3 결합제 및 산화적 스트레스와 연관되는 질환 / 급성 병태의 예방 또는 치료에서의 그의 용도 |
| CN113557031A (zh) * | 2018-12-21 | 2021-10-26 | 4Teen4制药有限公司 | 使用血管紧张肽受体激动剂和/或其前体的治疗的疗法指导和/或疗法监测 |
| EP4552649A3 (en) * | 2019-08-30 | 2025-06-25 | 4TEEN4 Pharmaceuticals GmbH | Therapy guidance and/or therapy monitoring for treatment of shock |
| CN115244401A (zh) | 2020-02-27 | 2022-10-25 | 4Teen4制药有限公司 | 用于在休克患者中进行nt-adm抗体的治疗指导、监测和分层的dpp3 |
| BR112022016843A2 (pt) | 2020-02-27 | 2022-10-11 | Adrenomed Ag | Ligante antiadrenomedulina (adm) para uso na terapia de pacientes em choque |
| AU2021227277A1 (en) * | 2020-02-27 | 2022-10-20 | Adrenomed Ag | Anti-Adrenomedullin (ADM) antibody or anti-ADM antibody fragment or anti-ADM non-Ig scaffold for use in therapy or prevention of shock |
| WO2021185786A1 (en) * | 2020-03-16 | 2021-09-23 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 in patients infected with coronavirus |
| EP3922993A1 (en) * | 2020-06-12 | 2021-12-15 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 in patients infected with coronavirus |
| AU2023233838A1 (en) | 2022-03-15 | 2024-09-26 | Adrenomed Ag | Stable aqueous formulation of an anti-adrenomedullin (adm) antibody or anti-adm antibody fragment |
| CN117186177B (zh) * | 2022-05-31 | 2024-08-23 | 中国农业大学 | 一种具有降尿酸活性的鸭血球蛋白肽及其制备方法 |
| AU2023315168A1 (en) | 2022-07-29 | 2025-02-13 | 4TEEN4 Pharmaceuticals GmbH | Prediction of an increase of dpp3 in a patient with septic shock |
| KR20250042158A (ko) | 2022-07-29 | 2025-03-26 | 아드레노메드 아게 | 쇼크의 요법 또는 예방에 사용하기 위한 항-아드레노메둘린 (ADM) 항체 또는 항-ADM 항체 단편 또는 항-ADM 비-Ig 스캐폴드 |
| EP4633659A1 (en) | 2022-12-15 | 2025-10-22 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 inhibitor for improvement of pulmonary function in critically ill patients |
| CN115804836A (zh) * | 2022-12-27 | 2023-03-17 | 中国人民解放军海军特色医学中心 | 一种中枢小分子蛋白dpp3在制备降压药物中的应用 |
| WO2024200862A1 (en) | 2023-03-29 | 2024-10-03 | 4TEEN4 Pharmaceuticals GmbH | Dpp3 inhibitor for myocardial protection and prevention of myocardial injury in critically ill patients with blood pressure decline |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| JPS6188884A (ja) | 1984-10-04 | 1986-05-07 | Sankyo Co Ltd | エンケフアリナ−ゼb阻害物質およびその製法 |
| AU634716B2 (en) | 1988-08-01 | 1993-03-04 | Ciba Corning Diagnostics Corp. | Method for detection of an analyte using acridinium esters and liposomes |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| ATE139258T1 (de) | 1990-01-12 | 1996-06-15 | Cell Genesys Inc | Erzeugung xenogener antikörper |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| GB9015198D0 (en) | 1990-07-10 | 1990-08-29 | Brien Caroline J O | Binding substance |
| DK0585287T3 (da) | 1990-07-10 | 2000-04-17 | Cambridge Antibody Tech | Fremgangsmåde til fremstilling af specifikke bindingsparelementer |
| EP0746609A4 (en) | 1991-12-17 | 1997-12-17 | Genpharm Int | NON-HUMAN TRANSGENIC ANIMALS CAPABLE OF PRODUCING HETEROLOGOUS ANTIBODIES |
| JPH06219989A (ja) * | 1993-01-27 | 1994-08-09 | Microbial Chem Res Found | 新規生理活性物質フルオスタチンaおよびb、その製造法およびその用途 |
| GB9312324D0 (en) * | 1993-06-15 | 1993-07-28 | Pitman Moore Inc | Vaccine |
| US5612186A (en) | 1994-06-22 | 1997-03-18 | Food Industry Research And Development Institute | Enzyme-capture assay (ECA) for the identification of Escherichia coli in clinical samples |
| US5601986A (en) | 1994-07-14 | 1997-02-11 | Amgen Inc. | Assays and devices for the detection of extrahepatic biliary atresia |
| US6818418B1 (en) | 1998-12-10 | 2004-11-16 | Compound Therapeutics, Inc. | Protein scaffolds for antibody mimics and other binding proteins |
| CA2383907A1 (en) | 1999-09-01 | 2001-03-08 | Incyte Genomics, Inc. | Human hydrolytic enzymes |
| AU2002225954A1 (en) * | 2000-11-08 | 2002-05-21 | The University Of Georgia Research Foundation, Inc. | Dipeptidylpeptidases and methods of use |
| JP2005508623A (ja) | 2001-08-30 | 2005-04-07 | バイオレクシス ファーマシューティカル コーポレイション | 改変されたトランスフェリン融合タンパク質 |
| PT1941867E (pt) | 2002-06-07 | 2012-02-16 | Dyax Corp | Polipeptídeo contendo um domínio kunitz modificado |
| CN1852974A (zh) * | 2003-06-09 | 2006-10-25 | 密歇根大学董事会 | 用于治疗和诊断癌症的组合物和方法 |
| AU2004284090A1 (en) | 2003-10-24 | 2005-05-06 | Avidia, Inc. | LDL receptor class A and EGF domain monomers and multimers |
| US20100028995A1 (en) | 2004-02-23 | 2010-02-04 | Anaphore, Inc. | Tetranectin Trimerizing Polypeptides |
| WO2005106486A2 (en) * | 2004-04-28 | 2005-11-10 | Bayer Healthcare Ag | Diagnostic and therapeutics for diseases associated with dipeptidyl-peptidase 3(dpp3) |
| US20110136131A1 (en) * | 2004-06-01 | 2011-06-09 | Sysmex Corporation | Method for measuring enzyme activity and column for use in measuring enzyme activity |
| EP2314308A1 (en) | 2004-09-21 | 2011-04-27 | BioNTech AG | Use of microproteins as tryptase inhibitors |
| JP2006230318A (ja) * | 2005-02-25 | 2006-09-07 | Maruishi Pharmaceutical Co Ltd | 関節リウマチの診断方法 |
| CN100420947C (zh) * | 2005-05-30 | 2008-09-24 | 孙东旭 | 用单一捕获剂定量检测特异性分析物的方法及其试剂盒 |
| US20070148130A1 (en) * | 2005-11-02 | 2007-06-28 | Tetsuya Gatanaga | Native TRRE: protein implicated in TNF receptor shedding for treating arthritis and inflammation |
| US8652789B2 (en) * | 2006-03-13 | 2014-02-18 | Becton, Dickinson And Company | Diagnosis and prognosis of dipeptidyl peptidase-associated disease states |
| EP2924440A3 (en) | 2006-06-07 | 2016-03-09 | Health Diagnostic Laboratory, Inc. | Markers associated with arteriovascular events and methods of use thereof |
| DK2231860T3 (da) | 2007-12-19 | 2011-12-05 | Affibody Ab | Polypeptid afledt protein A og i stand til at binde PDGF |
| WO2010060748A1 (en) | 2008-11-03 | 2010-06-03 | Molecular Partners Ag | Binding proteins inhibiting the vegf-a receptor interaction |
| US8715928B2 (en) * | 2009-02-13 | 2014-05-06 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Molecular-based method of cancer diagnosis and prognosis |
| CN102869678A (zh) | 2009-08-27 | 2013-01-09 | 科瓦根股份公司 | Il-17结合化合物及其医药用途 |
| EP2367843B1 (en) | 2009-12-14 | 2014-10-08 | Scil Proteins GmbH | Modified ubiquitin proteins having a specific binding activity for the extradomain b of fibronectin |
| KR101234352B1 (ko) * | 2010-03-18 | 2013-02-15 | 권동락 | 선택적 면역 세포 분리 반출장치 |
| HRP20190689T1 (hr) | 2010-06-08 | 2019-06-14 | Pieris Pharmaceuticals Gmbh | Muteini suznog lipokalina koji vežu il-4r alfa |
| MY200300A (en) * | 2016-04-21 | 2023-12-19 | 4TEEN4 Pharmaceuticals GmbH | Methods for determining dpp3 and therapeutic methods |
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