CN120118892A - 用于制备经蛋白水解处理的多肽的方法 - Google Patents

用于制备经蛋白水解处理的多肽的方法 Download PDF

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Publication number
CN120118892A
CN120118892A CN202510029795.7A CN202510029795A CN120118892A CN 120118892 A CN120118892 A CN 120118892A CN 202510029795 A CN202510029795 A CN 202510029795A CN 120118892 A CN120118892 A CN 120118892A
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polypeptide
clostridial neurotoxin
sequence
seq
amino acid
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CN202510029795.7A
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Chinese (zh)
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A·拉梅尔
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Ipsen Bioinnovation Ltd
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Ipsen Bioinnovation Ltd
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    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
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    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
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    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
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    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
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CN202510029795.7A 2012-11-21 2012-11-21 用于制备经蛋白水解处理的多肽的方法 Pending CN120118892A (zh)

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CN201280075874.2A CN104870468B (zh) 2012-11-21 2012-11-21 用于制备经蛋白水解处理的多肽的方法
PCT/EP2012/073283 WO2014079495A1 (en) 2012-11-21 2012-11-21 Methods for the manufacture of proteolytically processed polypeptides
CN202510029795.7A CN120118892A (zh) 2012-11-21 2012-11-21 用于制备经蛋白水解处理的多肽的方法

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CN201280075874.2A Active CN104870468B (zh) 2012-11-21 2012-11-21 用于制备经蛋白水解处理的多肽的方法
CN202010161444.9A Pending CN111454931A (zh) 2012-11-21 2012-11-21 用于制备经蛋白水解处理的多肽的方法
CN202010771933.6A Pending CN112048009A (zh) 2012-11-21 2013-11-21 用于制备经蛋白水解处理的多肽的方法
CN201380060742.7A Active CN104797595B (zh) 2012-11-21 2013-11-21 用于制备经蛋白水解处理的多肽的方法

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CN202010161444.9A Pending CN111454931A (zh) 2012-11-21 2012-11-21 用于制备经蛋白水解处理的多肽的方法
CN202010771933.6A Pending CN112048009A (zh) 2012-11-21 2013-11-21 用于制备经蛋白水解处理的多肽的方法
CN201380060742.7A Active CN104797595B (zh) 2012-11-21 2013-11-21 用于制备经蛋白水解处理的多肽的方法

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US (4) US10087432B2 (enExample)
JP (3) JP6156954B2 (enExample)
KR (4) KR102083371B1 (enExample)
CN (5) CN120118892A (enExample)
AR (3) AR093578A1 (enExample)
AU (2) AU2012395188B2 (enExample)
BR (2) BR112015003591B1 (enExample)
CA (2) CA2880897C (enExample)
IN (1) IN2015DN01449A (enExample)
MX (3) MX363788B (enExample)
RU (2) RU2673910C2 (enExample)
TW (5) TWI713862B (enExample)
UA (2) UA111795C2 (enExample)
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WO2023041934A1 (en) 2021-09-16 2023-03-23 Ipsen Biopharm Limited Modified bont/a for use in the treatment of cervical dystonia
GB202113602D0 (en) 2021-09-23 2021-11-10 Ipsen Biopharm Ltd Treatment of a disorder affecting an eyelid muscle of a subject
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CA3234608A1 (en) 2021-11-22 2023-05-25 Ipsen Biopharm Limited Treatment of pain
GB202206353D0 (en) 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of cervical dystonia
GB202206362D0 (en) 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of upper facial lines
GB202206348D0 (en) 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of limb spasticity
GB202206361D0 (en) 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of a facial dystonia
GB202213479D0 (en) 2022-09-14 2022-10-26 Ipsen Biopharm Ltd Cell-free clostridial neurotoxin assays
GB202307439D0 (en) 2023-05-18 2023-07-05 Ipsen Biopharm Ltd Treatment of a headache disorder with botylinum neurotoxin a
WO2025093845A1 (en) 2023-11-01 2025-05-08 Ipsen Biopharm Limited Use of high dose chimeric botulinum toxin a for the treatment of upper facial lines
WO2025093844A1 (en) 2023-11-01 2025-05-08 Ipsen Biopharm Limited Use of chimeric botulinum toxin a for treating blepharospasm and hemifacial spasm
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