CN1196785C - β-淀粉样肽结合蛋白及其编码聚核苷酸 - Google Patents

β-淀粉样肽结合蛋白及其编码聚核苷酸 Download PDF

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Publication number
CN1196785C
CN1196785C CNB988043173A CN98804317A CN1196785C CN 1196785 C CN1196785 C CN 1196785C CN B988043173 A CNB988043173 A CN B988043173A CN 98804317 A CN98804317 A CN 98804317A CN 1196785 C CN1196785 C CN 1196785C
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protein
bbp
sequence
polynucleotide
bap
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Expired - Fee Related
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CNB988043173A
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English (en)
Chinese (zh)
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CN1268973A (zh
Inventor
B·A·奥藏伯格
J·A·巴德
E·M·卡科斯基
J·S·雅各布森
S·G·沃克
H·索菲亚
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Wyeth LLC
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American Home Products Corp
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711Alzheimer's disease; Amyloid plaque core protein
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hospice & Palliative Care (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CNB988043173A 1997-04-16 1998-04-14 β-淀粉样肽结合蛋白及其编码聚核苷酸 Expired - Fee Related CN1196785C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6458397P 1997-04-16 1997-04-16
US60/064,583 1997-04-16

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNA200510052975XA Division CN1690203A (zh) 1997-04-16 1998-04-14 β-淀粉样肽结合蛋白及其编码聚核苷酸

Publications (2)

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CN1268973A CN1268973A (zh) 2000-10-04
CN1196785C true CN1196785C (zh) 2005-04-13

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ID=22056941

Family Applications (2)

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CNA200510052975XA Pending CN1690203A (zh) 1997-04-16 1998-04-14 β-淀粉样肽结合蛋白及其编码聚核苷酸
CNB988043173A Expired - Fee Related CN1196785C (zh) 1997-04-16 1998-04-14 β-淀粉样肽结合蛋白及其编码聚核苷酸

Family Applications Before (1)

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CNA200510052975XA Pending CN1690203A (zh) 1997-04-16 1998-04-14 β-淀粉样肽结合蛋白及其编码聚核苷酸

Country Status (18)

Country Link
EP (1) EP0975753A2 (id)
JP (3) JP2001523093A (id)
KR (1) KR20010006393A (id)
CN (2) CN1690203A (id)
AU (1) AU740445B2 (id)
BR (1) BR9808562A (id)
CA (1) CA2286484A1 (id)
EA (1) EA004256B1 (id)
EE (1) EE9900482A (id)
GE (1) GEP20043386B (id)
HU (1) HUP0003116A3 (id)
ID (1) ID24914A (id)
IL (3) IL132236A0 (id)
NO (1) NO995062L (id)
NZ (1) NZ500216A (id)
SK (1) SK143299A3 (id)
UA (1) UA72875C2 (id)
WO (1) WO1998046636A2 (id)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6787319B2 (en) * 1997-04-16 2004-09-07 American Home Products Corp. β-amyloid peptide-binding proteins and polynucleotides encoding the same
US7005295B1 (en) 1997-04-16 2006-02-28 Wyeth β-amyloid peptide-binding proteins and polynucleotides encoding the same
CA2346008A1 (en) * 1998-10-13 2000-04-20 American Home Products Corporation G-protein-coupled receptor-like proteins, polynucleotides encoded by them, and methods of using same
US6455082B1 (en) * 1999-04-26 2002-09-24 Nestec S.A. Shelf-stable calcium fortified milk and dairy products
AU4183200A (en) * 1999-10-21 2001-04-30 Panorama Research, Inc. A general method for optimizing the expression of heterologous proteins
US8663650B2 (en) 2003-02-21 2014-03-04 Ac Immune Sa Methods and compositions comprising supramolecular constructs
US7807171B2 (en) 2003-07-25 2010-10-05 Ac Immune Sa Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers
EP2603233A1 (en) 2010-08-12 2013-06-19 AC Immune S.A. Vaccine engineering
CN103189050B (zh) 2010-10-26 2017-09-29 Ac免疫有限公司 包含通过疏水部分修饰的肽的基于脂质体的构建体
CN102060912B (zh) * 2010-11-22 2012-11-14 清华大学 淀粉样蛋白寡聚体构象型抗原表位多肽及其应用
CN111320678B (zh) * 2020-03-09 2023-06-09 安亭生物有限责任公司 抗菌肽突变体及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE169673T1 (de) * 1986-11-17 1998-08-15 Scios Inc Rekombiniertes alzheimer amyloid-protein
IL115743A0 (en) * 1994-10-28 1996-01-19 American Nat Red Cross A mammal with cells containing a transgene and its production
US5786180A (en) * 1995-02-14 1998-07-28 Bayer Corporation Monoclonal antibody 369.2B specific for β A4 peptide

Also Published As

Publication number Publication date
EP0975753A2 (en) 2000-02-02
NO995062L (no) 1999-12-14
BR9808562A (pt) 2000-05-23
CN1268973A (zh) 2000-10-04
AU7115698A (en) 1998-11-11
EA199900941A1 (ru) 2000-06-26
JP2008253275A (ja) 2008-10-23
CN1690203A (zh) 2005-11-02
WO1998046636A2 (en) 1998-10-22
IL179047A0 (en) 2007-03-08
CA2286484A1 (en) 1998-10-22
GEP20043386B (en) 2004-02-10
SK143299A3 (en) 2000-09-12
JP2008104465A (ja) 2008-05-08
WO1998046636A3 (en) 1999-01-28
EA004256B1 (ru) 2004-02-26
IL132236A (en) 2007-03-08
EE9900482A (id) 2000-06-15
NO995062D0 (no) 1999-10-15
NZ500216A (en) 2001-06-29
KR20010006393A (ko) 2001-01-26
HUP0003116A3 (en) 2003-03-28
JP2001523093A (ja) 2001-11-20
AU740445B2 (en) 2001-11-01
IL132236A0 (en) 2001-03-19
HUP0003116A2 (hu) 2001-01-29
ID24914A (id) 2000-08-31
UA72875C2 (uk) 2005-05-16

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Granted publication date: 20050413