CN117547505A - Preparation method of massage cream for relaxing and activating channels and collaterals - Google Patents

Preparation method of massage cream for relaxing and activating channels and collaterals Download PDF

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CN117547505A
CN117547505A CN202410037706.9A CN202410037706A CN117547505A CN 117547505 A CN117547505 A CN 117547505A CN 202410037706 A CN202410037706 A CN 202410037706A CN 117547505 A CN117547505 A CN 117547505A
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relaxing
massage cream
parts
muscles
weight
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CN117547505B (en
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陈武辉
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Guangzhou Fayasi Fine Chemical Co ltd
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Abstract

The invention discloses a preparation method of a massage cream for relaxing the muscles and joints and belongs to the field of massage cream. The emulsion preservative with the functions of both the emulsifier and the preservative contains taurine: antioxidant, it enhances cortical cell activity, inhibits skin allergy, and also is anti-inflammatory; eugenol: has antibacterial, analgesic, antiinflammatory, hemostatic effects, and can be used for controlling oil secretion and treating skin infection; cysteine: is an amino acid with antioxidant effect, and can remove free radicals; in addition, cysteine can also be used for treating wounds, preventing eczema and the like, and can be used as a nutritional additive and an anti-inflammatory agent; therefore, the emulsifying preservative can reduce the dosage and variety of the emulsifying preservative, so that the variety of low-temperature raw materials of the massage cream for relaxing the muscles and joints is reduced, the cost is reduced, and the efficacy is improved.

Description

Preparation method of massage cream for relaxing and activating channels and collaterals
Technical Field
The invention relates to the field of massage cream, in particular to a preparation method of massage cream for relaxing the muscles and joints.
Background
The massage cream for relaxing the muscles and joints and activating the collaterals is mainly used for treating pain caused by common aseptic inflammation in clinic, can also be applied to knee osteoarthritis, cervical spondylosis, lumbago and skelalgia and scapulohumeral periarthritis, and can also be used for treating limb joint pain and diseases with unfavorable activities caused by blood stasis and swelling and pain in the later stage of traumatic injury; the massage cream for relaxing the muscles and joints is externally applied to the pain parts, most of the massage cream can play a role in relieving pain, and also can play roles in promoting inflammatory absorption, activating blood circulation to dissipate blood stasis and dredging collaterals to relieve pain.
Chinese patent CN105079760B: discloses lavender massage cream for soothing channels and activating collaterals. The lavender massage cream for soothing channels and activating collaterals comprises the following components: water, glycerin, lavandula angustifolia essential oil, safflower oil, ginger oil, white oil, xanthan gum, dodecyl glucoside, polyglycerol-2-dimer hydroxystearate, menthol, linalool, squalane, sesame seed oil, gluconic acid, sodium benzoate, potassium sorbate, camphor, juniper berry extract, hollyhock, magnolia bark root extract, witch hazel extract, calcium gluconate, geraniol, limonene, gluconolactone, hollyhock root extract, and abaca root extract.
Chinese patent CN111617182a: the invention discloses a tendon relaxing and collateral activating active plaster which comprises the following components in parts by weight: 8-15% of konjaku flour, 19-27% of gardenia powder, 26-37% of rhizoma paridis powder, 3-5% of camphor, 3-7% of menthol and 21-28% of vaseline.
Chinese patent CN105213242a: the massage cream comprises the following components in parts by weight: 5-20 parts of Sichuan green, 10-20 parts of ginkgo, 25-50 parts of red sage root, 5-10 parts of safflower, 20-40 parts of brown sugar, 10-25 parts of ginger, 30-50 parts of red date, 10-30 parts of aconite, 30-60 parts of vaseline and 200-400 parts of water.
The massage cream for relaxing the channels and activating collaterals prepared by the above patent and the prior art has unsatisfactory effects on swelling, pain, soothing and calming the skin and the like, and has low treatment efficiency.
Disclosure of Invention
In order to solve the problems, the invention provides a preparation method of massage cream for relaxing the muscles and joints, which comprises the following operation steps:
s1: weighing 60-80 parts by weight of water, 0.0001-0.001 part by weight of safflower extract, 0.0001-0.001 part by weight of ginseng root extract, 0.0001-0.001 part by weight of red sage root extract, 0.0001-0.001 part by weight of ligusticum rhizome root extract, 0.0001-0.001 part by weight of radix paeoniae rubra root extract, 0.001-0.003 part by weight of butanediol, 0.001-0.005 part by weight of 1, 2-hexanediol, emollient, humectant, thickener, thermal sensitizer and 0.07-0.7 part by weight of emulsifying preservative, adding into a vacuum emulsifying pot, mixing and stirring for 10-30min;
s2: heating to 50-70deg.C, stirring for 60-90min, homogenizing for 30-60min;
s3: finally, 0.01 to 0.1 part of essence, cooling agent and coloring agent are added and stirred for 10 to 20 minutes to obtain the massage cream for relaxing the muscles and joints.
Preferably, the emollient is: 1-5 parts of isopropyl palmitate, 0.1-0.5 part of tocopheryl acetate, 0.02-0.2 part of propylene glycol, 0.001-0.01 part of gentian extract and 0.01-0.1 part of ginger root oil.
Preferably, the humectant is: 1-4 parts of glycerin, 1-3 parts of propylene glycol and 0.02-0.2 part of allantoin.
Preferably, the preparation method of the emulsion preservative comprises the following steps:
adding 3-6 parts of acryloyldimethyl taurine, 16-32 parts of eugenol, 17-34 parts of cysteine, 0.003-0.06 part of dioctadecylamine, 0.6-2.4 parts of triethanolamine and 200-240 parts of ethanol into a dry three-neck flask according to parts by weight; the reaction temperature is controlled at 50-60 ℃, nitrogen is introduced for protection in the reaction process, the reaction time is 20-60min, and then ethanol is distilled to obtain the emulsified preservative.
Preferably, the thermal sensitizer is 0.06-0.12 parts of vanillyl butyl ether.
Preferably, the thickener is 0.1-0.5 parts of xanthan gum.
Preferably, the cooling agent is menthol 0.01-0.04 parts.
Preferably, the colorant is: 0.001-0.01 part of CI19140, 0.0005-0.002 part of CI16255, 0.0001-0.0006 part of CI 42090.
The reaction mechanism of the emulsion preservative is as follows: the acryl dimethyl taurine and the eugenol respectively undergo sulfhydryl-alkene addition reaction with cysteine; performing amino-alkene addition reaction with dioctadecylamine; an emulsified preservative with both the functions of an emulsifier and a preservative is obtained.
In summary, the present application has the following beneficial effects:
1. the massage cream for relaxing the muscles and activating the collaterals, which is prepared by the invention, is matched with a massage technique for local external use, can relieve the symptoms of local muscle adhesion, calcification and the like which occur after local soft tissue injury occurs after trauma, and has conditioning effects on joint swelling, pain, limited movement and the like caused by osteoarthritis;
2. the massage cream for relaxing the muscles and joints prepared by the invention can be externally rubbed to treat lumbar postoperative lower back pain, has the effects of activating blood circulation, removing obstruction in collaterals, removing stasis, relieving pain, soothing and calming skin and the like, and can be matched with massage manipulation to adjust the internal and external balance;
3. the emulsion preservative with the functions of both the emulsifier and the preservative contains taurine: antioxidant, it enhances cortical cell activity, inhibits skin allergy, and also is anti-inflammatory; eugenol: has antibacterial, analgesic, antiinflammatory, hemostatic effects, and can be used for controlling oil secretion and treating skin infection; cysteine: is an amino acid with antioxidant effect, and can remove free radicals; in addition, cysteine can also be used for treating wounds, preventing eczema and the like, and can be used as a nutritional additive and an anti-inflammatory agent; therefore, the emulsifying preservative can reduce the dosage and variety of the emulsifying preservative, so that the variety of low-temperature raw materials of the massage cream for relaxing the muscles and joints is reduced, the cost is reduced, and the efficacy is improved.
Detailed Description
The technical solutions of the present invention will be clearly and completely described in connection with the embodiments, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
In the embodiment, the massage is used for treating lumbar postoperative lower back pain by combining with meridian-soothing and collateral-activating massage cream by external rubbing, and the curative effect is checked for 70 people: 35 men and 35 women; average 7 groups of 10 people: 5 men and 5 women, performing a test; age 35-70 years, 1 week is a course of treatment, 3 courses of treatment altogether;
pain grades were: mild, moderate, severe;
the curative effect grade is as follows: the cure is changed from severe to mild, the pain is reduced by 1 degree to effective, and the pain is not improved to ineffective.
Example 1, a preparation method of a massage cream for relaxing the muscles and joints, which comprises the following steps:
s1: weighing 60g of water, 0.0001g of safflower extract, 0.0001g of ginseng root extract, 0.0001g of red sage root extract, 0.0001g of ligusticum wallichii root extract, 0.0001g of radix paeoniae rubra root extract, 0.001g of butanediol, 0.001g of 1, 2-hexanediol, an emollient, a humectant, a thickener, a thermal sensitizer and 0.07g of emulsifying preservative, adding into a vacuum emulsifying pot, mixing and stirring for 10min;
s2: heating to 50deg.C, stirring for 60min, and homogenizing for 30min;
s3: finally, 0.01g of essence, cooling agent and coloring agent are added and stirred for 10min to obtain the massage cream for relaxing the channels and activating the collaterals.
The emollient is as follows: 1g isopropyl palmitate, 0.1g tocopheryl acetate, 0.02g propylene glycol, 0.001g gentian extract, 0.01g ginger root oil.
The humectant is as follows: a mixture of 1g glycerol, 1g propylene glycol, 0.02g allantoin.
The preparation method of the emulsion preservative comprises the following steps:
into a dry three-neck flask, 3g of acryloyldimethyl taurine, 16g of eugenol, 17g of cysteine, 0.003g of dioctadecylamine, 0.6g of triethanolamine and 200g of ethanol were added; the reaction temperature is controlled at 50 ℃, nitrogen is introduced for protection in the reaction process, the reaction time is 20min, and then ethanol is distilled, so that the emulsified preservative is obtained.
The thermal sensitizer is 0.06g of vanillyl butyl ether.
The thickener is 0.1g of xanthan gum.
The cooling agent is menthol 0.01 g.
The coloring agent is as follows: 0.001g of CI19140, 0.0005g of CI16255, 0.0001g of CI42090.
Example 2, a preparation method of a massage cream for relaxing the muscles and joints, which comprises the following steps:
s1: 65g of water, 0.0005g of safflower extract, 0.0005g of ginseng root extract, 0.0005g of red sage root extract, 0.0005g of ligusticum wallichii root extract, 0.0005g of radix paeoniae rubra root extract, 0.002g of butanediol, 0.002g of 1, 2-hexanediol, an emollient, a humectant, a thickener, a thermal sensitizer and 0.2g of emulsifying preservative are weighed, added into a vacuum emulsifying pot, mixed and stirred for 15min;
s2: heating to 55deg.C, stirring for 70min, homogenizing for 40min;
s3: finally, 0.05g of essence, cooling agent and coloring agent are added and stirred for 15min to obtain the massage cream for relaxing the channels and activating the collaterals.
The emollient is as follows: a mixture of 2g isopropyl palmitate, 0.2g tocopheryl acetate, 0.1g propylene glycol, 0.005g gentian extract, 0.05g ginger root oil.
The humectant is as follows: a mixture of 2g glycerol, 2g propylene glycol, 0.1g allantoin.
The preparation method of the emulsion preservative comprises the following steps:
into a dry three-neck flask, 4g of acryloyldimethyl taurine, 22g of eugenol, 23g of cysteine, 0.2g of dioctadecylamine, 1g of triethanolamine and 210g of ethanol are added; the reaction temperature is controlled at 55 ℃, nitrogen is introduced for protection in the reaction process, the reaction time is 30min, and then ethanol is distilled, so that the emulsified preservative is obtained.
The thermal sensitizer is 0.08g of vanillyl butyl ether.
The thickener is 0.2g of xanthan gum.
The cooling agent is menthol 0.02 g.
The coloring agent is as follows: 0.005g of CI19140, 0.001g of CI16255, 0.0002g of CI42090.
Example 3, a preparation method of a massage cream for relaxing the muscles and joints, which comprises the following steps:
s1: weighing 75g of water, 0.0008g of safflower extract, 0.0008g of ginseng root extract, 0.0008g of red sage root extract, 0.0008g of ligusticum wallichii root extract, 0.0008g of radix paeoniae rubrathe root extract, 0.002g of butanediol, 0.004g of 1, 2-hexanediol, an emollient, a humectant, a thickener, a heat sensitizer and 0.5g of emulsifying preservative, adding into a vacuum emulsifying pot, mixing and stirring for 25min;
s2: heating to 65deg.C, stirring for 80min, homogenizing for 50min;
s3: finally, 0.08g of essence, cooling agent and coloring agent are added and stirred for 15min to obtain the massage cream for relaxing the channels and activating the collaterals.
The emollient is as follows: a mixture of 4g isopropyl palmitate, 0.4g tocopheryl acetate, 0.15g propylene glycol, 0.008g gentian extract, 0.08g ginger root oil.
The humectant is as follows: 3g of glycerol, 2g of propylene glycol, 0.15g of allantoin.
The preparation method of the emulsion preservative comprises the following steps:
into a dry three-neck flask, 5g of acryloyldimethyl taurine, 28g of eugenol, 30g of cysteine, 0.04g of dioctadecylamine, 2g of triethanolamine and 230g of ethanol are added; the reaction temperature is controlled at 55 ℃, nitrogen is introduced for protection in the reaction process, the reaction time is 50min, and then ethanol is distilled to obtain the emulsified preservative.
The thermal sensitizer is 0.1g of vanillyl butyl ether.
The thickener is 0.4g of xanthan gum.
The cooling agent is menthol 0.03 g.
The coloring agent is as follows: 0.008g of CI19140, 0.0015g of CI16255 and 0.0005g of CI42090.
Example 4, a preparation method of a massage cream for relaxing the muscles and joints, which comprises the following steps:
s1: weighing 80g of water, 0.001g of safflower extract, 0.001g of ginseng root extract, 0.001g of red sage root extract, 0.001g of ligusticum wallichii root extract, 0.001g of radix paeoniae rubra root extract, 0.003g of butanediol, 0.005g of 1, 2-hexanediol, an emollient, a humectant, a thickener, a thermal sensitizer and 0.7g of emulsifying preservative, adding into a vacuum emulsifying pot, mixing and stirring for 30min;
s2: heating to 70deg.C, stirring for 90min, and homogenizing for 60min;
s3: finally, 0.1g of essence, cooling agent and coloring agent are added and stirred for 20min to obtain the massage cream for relaxing the channels and activating the collaterals.
The emollient is as follows: a mixture of 5g isopropyl palmitate, 0.5g tocopheryl acetate, 0.2g propylene glycol, 0.01g gentian extract, 0.1g ginger root oil.
The humectant is as follows: a mixture of 4g glycerol, 3g propylene glycol, 0.2g allantoin.
The preparation method of the emulsion preservative comprises the following steps:
into a dry three-neck flask, 6g of acryloyldimethyl taurine, 32g of eugenol, 34g of cysteine, 0.06g of dioctadecylamine, 2.4g of triethanolamine and 240g of ethanol were added; the reaction temperature is controlled at 60 ℃, nitrogen is introduced for protection in the reaction process, the reaction time is 60min, and then ethanol is distilled to obtain the emulsified preservative.
The thermal sensitizer is 0.12g of vanillyl butyl ether.
The thickener is 0.5g of xanthan gum.
The cooling agent is menthol 0.04 g.
The coloring agent is as follows: 0.01g of CI19140, 0.002g of CI16255, 0.0006g of CI42090.
Comparative example 1 was conducted in the same manner as in example 1 except that acryloyldimethyl taurinic acid was not added.
Comparative example 2 eugenol was not added, and the same procedure was followed as in example 1.
Comparative example 3 distearyl amine was not added, otherwise as in example 1.
Through the data analysis of the examples and the comparative examples, the massage cream for relaxing the muscles and joints prepared by the invention can play roles in promoting blood circulation and removing obstruction in collaterals, dispersing blood stasis and relieving pain, soothing and calming skin and the like after lumbar vertebra operation by external rubbing, and can adjust the curative effect of internal and external balance by matching with massage manipulation.
The preferred embodiments of the invention disclosed above are intended only to assist in the explanation of the invention. The preferred embodiments are not intended to be exhaustive or to limit the invention to the precise form disclosed. Obviously, many modifications and variations are possible in light of the above teaching. The embodiments were chosen and described in order to best explain the principles of the invention and the practical application, to thereby enable others skilled in the art to best understand and utilize the invention. The invention is limited only by the claims and the full scope and equivalents thereof.

Claims (8)

1. A preparation method of the massage cream for relaxing the muscles and joints comprises the following operation steps:
s1: weighing 60-80 parts by weight of water, 0.0001-0.001 part by weight of safflower extract, 0.0001-0.001 part by weight of ginseng root extract, 0.0001-0.001 part by weight of red sage root extract, 0.0001-0.001 part by weight of ligusticum rhizome root extract, 0.0001-0.001 part by weight of radix paeoniae rubra root extract, 0.001-0.003 part by weight of butanediol, 0.001-0.005 part by weight of 1, 2-hexanediol, emollient, humectant, thickener, thermal sensitizer and 0.07-0.7 part by weight of emulsifying preservative, adding into a vacuum emulsifying pot, mixing and stirring for 10-30min;
s2: heating to 50-70deg.C, stirring for 60-90min, homogenizing for 30-60min;
s3: finally, 0.01 to 0.1 part of essence, cooling agent and coloring agent are added and stirred for 10 to 20 minutes to obtain the massage cream for relaxing the muscles and joints.
2. The method for preparing the massage cream for relaxing the muscles and joints according to claim 1, wherein the method comprises the following steps: the emollient is as follows: 1-5 parts of isopropyl palmitate, 0.1-0.5 part of tocopheryl acetate, 0.02-0.2 part of propylene glycol, 0.001-0.01 part of gentian extract and 0.01-0.1 part of ginger root oil.
3. The method for preparing the massage cream for relaxing the muscles and joints according to claim 1, wherein the method comprises the following steps: the humectant is as follows: 1-4 parts of glycerin, 1-3 parts of propylene glycol and 0.02-0.2 part of allantoin.
4. The method for preparing the massage cream for relaxing the muscles and joints according to claim 1, wherein the method comprises the following steps: the preparation method of the emulsion preservative comprises the following steps:
adding 3-6 parts of acryloyldimethyl taurine, 16-32 parts of eugenol, 17-34 parts of cysteine, 0.003-0.06 part of dioctadecylamine, 0.6-2.4 parts of triethanolamine and 200-240 parts of ethanol into a dry three-neck flask according to parts by weight; the reaction temperature is controlled at 50-60 ℃, nitrogen is introduced for protection in the reaction process, the reaction time is 20-60min, and then ethanol is distilled to obtain the emulsified preservative.
5. The method for preparing the massage cream for relaxing the muscles and joints according to claim 1, wherein the method comprises the following steps: the thermal sensitizer is 0.06-0.12 part of vanillyl butyl ether.
6. The method for preparing the massage cream for relaxing the muscles and joints according to claim 1, wherein the method comprises the following steps: the thickener is 0.1-0.5 part of xanthan gum.
7. The method for preparing the massage cream for relaxing the muscles and joints according to claim 1, wherein the method comprises the following steps: the cooling agent is menthol 0.01-0.04 parts.
8. The method for preparing the massage cream for relaxing the muscles and joints according to claim 1, wherein the method comprises the following steps: the coloring agent is as follows: 0.001-0.01 part of CI19140, 0.0005-0.002 part of CI16255, 0.0001-0.0006 part of CI 42090.
CN202410037706.9A 2024-01-10 2024-01-10 Preparation method of massage cream for relaxing and activating channels and collaterals Active CN117547505B (en)

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KR102611063B1 (en) * 2023-09-15 2023-12-07 김유진 Massage cream composition and method for manufacturing the same.

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