CN106474439A - A kind of have heat-clearing and toxic substances removing, the Chinese medicinal ointment of removing heat from blood and promoting blood circulation function and preparation method thereof - Google Patents
A kind of have heat-clearing and toxic substances removing, the Chinese medicinal ointment of removing heat from blood and promoting blood circulation function and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of have heat-clearing and toxic substances removing, the Chinese medicinal ointment of removing heat from blood and promoting blood circulation function and preparation method thereof, the active component of described Chinese medicinal ointment includes the crude drug of following weight portion：5 15 parts of Lignum Aquilariae Resinatum, 28 parts of Radix Ginseng, 38 parts of Herba Artemisiae Annuae, 26 parts of Rhizoma Zingiberis Recens, 24 parts of green tea, 24 parts of Cortex Pini, 25 parts of the Radix Paeoniae Alba, 25 parts of Radix Notoginseng, 28 parts of Folium Artemisiae Argyi, 24 parts of Folium Mori, 24 parts of Camphora, 24 parts of Pericarpium Citri Reticulatae Viride grass.The Chinese medicinal ointment composition of the present invention is simple, and rationally, prescription is precise and appropriate for compatibility, side has heat clearing and damp drying, removing toxic substances and promoting subsidence of swelling, promoting blood circulation and stopping pain, effect of cooling blood for hemostasis entirely, it is suitable for various areas and patients with deep burn, quickly alleviating pain, infection, healing is fast, promote wound surface to repair rapidly, have no toxic side effect, the wound surface through treatment is smooth, healing quality is good, can effectively prevent the formation of skin scar；There is significant therapeutic effect to persistent ailments such as acute hemorrhoid, to chemicotherapy dermal tissue insult, repair rapid, effect is significant.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine preparation, more particularly it relates to one kind has heat-clearing and toxic substances removing, removing heat from blood is lived
Chinese medicinal ointment of blood function and preparation method thereof.
Background technology
Burn, scald are a kind of commonly encountered diseases, frequently-occurring disease.According to the incomplete statistics in recent years of relevant city burn center, burn
Patient's general mortality rate is 6.87%, and wherein burn surface area more than 80% person's mortality rate is 60.59%.Illustrate that Burns are treated still
There are certain difficulty, especially extensive deep burn, be the very high wound of mortality rate.Modern medicine is total to the treatment of burn
Can be divided into：One is the prevention and treatment of Burn shock, and two is preventing and treating and the nutrition of burn infection, and three is the place of complication of burn
Reason, four is the covering of burn wound.Rationally effectively process the key that wound surface is treatment burn.At present mostly with antibiotic control
Infection, rigorous aseptic.Anesthesia is cut crust, cuts crust, autologous skin or heterodermic graft flap coverage.In whole therapeutic process, depth
Burn generally requires Repeated Operation, and needs higher nursing condition and equipment, brings great misery to burn patient.
Traditional surgery of Chinese medicine treatment burn, before more than 2,000 years《Huang di's Canon of Medicine》Arrive the Tang Dynasty《Prescriptions worth thousand gold》Have
Cross record and illustrate.There has been the Chinese medicine scald medicament that many treatments are scalded, burnt in recent years, wherein as " JINGWANHONG " medicament for treating scald
And aseptic environment do not emphasized by the medicine such as " moist expose burn ointment " when having infection, treatment in itself, need not anaesthetize can pain relieving and little
Area Burn, is not required to the feature of skin-grafting etc..But the overall process for the treatment of III degree burn is (i.e. from eschar phase, infection period to granulation promoting skin
The reparation phase), due to III degree burn, condition of the injury weight, the course of disease are long, and pathological development change is many, and its clinical therapeutic efficacy is still undesirable.
The burn wound for the treatment of at present Chinese and western medicine external used medicine species is a lot of, and Chinese medicine formula multicomponent therein is complicated, and makes
Preparation Method is loaded down with trivial details, for example entitled " ointment for treating burn and preparation method ", the Chinese patent of Patent No. " CN200510017672 ",
Up to as many as 25 kinds of its Chinese medicine ingredients, and preparation method is complex；Also there is the simple ointment of some Chinese medicine formulas, it cures effect
Fruit is less desirable, and the China of for example entitled " ointment for treating burn and preparation method ", Patent No. " 200510017672 " is specially
Profit.
Burn and refer to by heating power and action of chemicals after human body, to the damage caused by the local organization of human body.Its
In heating power include burn and scald, cold injury and electricity wound etc..Western medical treatment is burnt and is mainly stopped using hydrogen peroxide debridement with through liquid medicine sterilization
Blood, and the sterilizing objects such as iodine tincture, take antibiotic medicine simultaneously in also needing.However, can not make in the case of the wound burnt relatively depth
With mercurochrome, and red tribute can not be used with iodine, easily makes human body produce iodate tribute poisoning.
Hemorrhoid are ancient names of disease, can trace back to Qin Han dynasty to the understanding of hemorrhoid." hemorrhoid " develop from " temple ", early in
《Sufficient arm 11 arteries and veins moxibustion warp》In be just related to the record at " temple ".《Plain Questions vital QI of the body connecting with natural QI is discussed》Carry：" thus be satiated with food, flaccidity of muscles and vessels,
Intestinal is swum as hemorrhoid." explicitly pointed out hemorrhoid formation relevant with eating and drinking without temperance, and point out that the pathology of hemorrhoid is " flaccidity of muscles and vessels ", i.e. venation
Blood vessel is indulged relaxation and is not received.《Compendium of medicine》Description hemorrhoid are " such as to have hill to project as hemorrhoid in pool greatly；In people's nine orifices, all have little meat to dash forward
Go out all day hemorrhoid ".Hemorrhoid are the common disease of anorectum department, and doctor trained in Western medicine is a lot of with regard to the therapeutic modality of hemorrhoid, but is to eliminate symptom as mesh mostly
, " flaccidity of muscles and vessels " this pathology can not be eliminated, therefore most hemorrhoid need operative treatment, but postoperative overwhelming majority patient
When hurt like hell, particularly dressing or first defecation, pain is more severe.Chinese medicine thinks, the generation of hemorrhoid disease is mostly by diet
Do not save, rheumatism downward attack by pathogenic heat large intestine, pyretic toxicity pents up, heat in blood dryness of the intestine, and poly- not the dissipating of knot forms.The treatment of hemorrhoid is more thorny, often
Easily recur.At present, the method treating acute hemorrhoid is more, is most commonly used that operative treatment and Drug therapy, and operative treatment is created
Wound is big, is not typically easily accepted by the patient, and the medicine for the treatment of hemorrhoid is more, has Western medicine and Chinese medicine, whether Western medicine or Chinese medicine are equal
There is a problem of that slowly effect, therapeutic effect are poor.
Therefore, feasible effective medicine is badly in need of in the treatment to above-mentioned pertinacious disease.
Content of the invention
Based on this, in order to overcome the defect of above-mentioned prior art, the invention provides one kind has heat-clearing and toxic substances removing concurrently, removing heat from blood is lived
Chinese medicinal ointment of blood function and preparation method thereof, can such as be scalded with effectively treatment, burn, burning, cell is subject to after hemorrhoid, chemicotherapy
The persistent ailments such as damage.
In order to realize foregoing invention purpose, this invention takes technical scheme below：
A kind of have heat-clearing and toxic substances removing, a Chinese medicinal ointment of removing heat from blood and promoting blood circulation function, the active component of described Chinese medicinal ointment include with
The crude drug of lower weight portion：Lignum Aquilariae Resinatum 5-15 part, Radix Ginseng 2-8 part, Herba Artemisiae Annuae 3-8 part, Rhizoma Zingiberis Recens 2-6 part, green tea 2-4 part, Cortex Pini 2-4
Part, Radix Paeoniae Alba 2-5 part, Radix Notoginseng 2-5 part, Folium Artemisiae Argyi 2-8 part, Folium Mori 2-4 part, Camphora 2-4 part, Pericarpium Citri Reticulatae Viride grass 2-4 part.
Wherein in some embodiments, the active component of described Chinese medicinal ointment includes the crude drug of following weight portion：Lignum Aquilariae Resinatum
10-15 part, Radix Ginseng 4-6 part, Herba Artemisiae Annuae 4-8 part, Rhizoma Zingiberis Recens 2-4 part, green tea 2-3 part, Cortex Pini 2-3 part, Radix Paeoniae Alba 2-4 part, Radix Notoginseng 2-4
Part, Folium Artemisiae Argyi 4-8 part, Folium Mori 2-3 part, Camphora 2-3 part, Pericarpium Citri Reticulatae Viride grass 2-3 part.
Wherein in some embodiments, the active component of described Chinese medicinal ointment includes the crude drug of following weight portion：Lignum Aquilariae Resinatum
15 parts, 5 parts of Radix Ginseng, 6 parts of Herba Artemisiae Annuae, 3 parts of Rhizoma Zingiberis Recens, 2 parts of green tea, 2 parts of Cortex Pini, 3 parts of the Radix Paeoniae Alba, 2 parts of Radix Notoginseng, 6 parts of Folium Artemisiae Argyi, 2 parts of Folium Mori,
2 parts of Camphora, 2 parts of Pericarpium Citri Reticulatae Viride grass.
Wherein in some embodiments, described Chinese medicinal ointment also includes the white vaseline equal with crude drug total weight parts.
Present invention also offers above-mentioned have heat-clearing and toxic substances removing, the preparation method of the Chinese medicinal ointment of removing heat from blood and promoting blood circulation function, it is
Art or low-temperature extraction art are distilled by prior art High Temperature High Pressure, obtains the extracting solution of each crude drug, mix, add Bai Fanshi
Woods, mixes, becomes unguentum.
The present invention there is heat-clearing and toxic substances removing, each crude drug of the active component of the Chinese medicinal ointment of removing heat from blood and promoting blood circulation function has respectively
There is following effect：
Lignum Aquilariae Resinatum is a kind of conventional Chinese medicine, be Isolated From Thymelaeaceae Species Lignum Aquilariae Resinatum Aquilariasinensis (Lour.) Gilg or
The desiccated wood containing resin of Lignum Aquilariae Resinatum A.agallochaRoxb., the former mainly originates in China, and the latter mainly originates in Ma Laixi
The states such as Asia, Indonesia and Vietnam.Modern pharmacological research shows, Lignum Aquilariae Resinatum has calmness, arrhythmia, suppression nervus centraliss
System, antibacterial anti-inflammatory etc. act on.In the middle of world's all spices, Lignum Aquilariae Resinatum is the most magical, first of many perfume, collection world abnormal smells from the patient one,
Dissipating food sexual urge is a side, is referred to as the diamond in plant, is all first from ancient times to the present for quality.Joining in the present invention
Fang Zhong, Lignum Aquilariae Resinatum acts primarily as the effect repairing skin.
Radix Ginseng (Panax ginseng C.A.Mey) is herbaceos perennial, originates in Northeast China, Korea, Korea S, day
Originally, Russian east.The another name of Radix Ginseng is Sphallerocarpus gracilis, Herba Stellariae Saxatilis, SHENCAO, the king of BAICAO, is one of well-known " northeast three essentials-essence ".
The superfine product of " king of BAICAO " " YIN nourishing mends life, strengthening the body resistance " is described as by Radix Ginseng from ancient times, containing multiple Saponins and polysaccharide constituents, leachate
Can slowly be absorbed and no pessimal stimulation by skin, energy skin expansion blood capillary, promote cutaneous circulation, increase skin and seek
Support, adjust the water and oil balance of skin, prevent skin dehydration, hardening, wrinkling, the fleshy tap root of Radix Ginseng is famous strong tonic, suitable
For adjusting blood pressure, recovering the diseases such as cardiac function, neurasthenia and physical weakness, also there are the work(such as eliminating the phlegm, stomach invigorating, diuresis, excitement
Effect.
Chinese medicine Herba Artemisiae Annuae, is the dry aerial parts of feverfew Herba Artemisiae Annuae Artemisia annua L..Bud stage harvests, and cuts
Take aerial partss, chopping, dry.Ancient name " " (q ì n).Clearing away summer-heat, except steaming, preventing the attack (or recurrence) of malaria.Generate heat for pathogenic summer-heat, fever due to yin deficiency,
Night fever abating at dawn, hectic fever due to YIN-deficiency consumptive fever, malaria cold and heat, jaundice due to damp-heat.It is a kind of cheap antimalarial drug.Clear deficiency-heat, removing heat from blood removes and steams, solution
Summer-heat, preventing the attack (or recurrence) of malaria.For pathogenic summer-heat heating, fever due to yin deficiency, night fever abating at dawn, hectic fever due to YIN-deficiency consumptive fever, malaria cold and heat, jaundice due to damp-heat.
Modern pharmacological research shows, Rhizoma Zingiberis Recenss have antibacterial, anticancer, and antioxidation, anti-aging effects, relieving exterior syndrome and dispelling cold, warming middle-JIAO
Preventing or arresting vomiting, warming the lung to relieve cough.It is usually used in Deficiency and coldness of spleen and stomach, loss of appetite, nausea and vomiting, or vomiting due to fluid-retention, the vomiting of disorder of stomach-QI, wind and cold
Or cold-phlegm cough, cold, fever with aversion to wind, nasal obstruction headache.It can also solve the drug intoxication such as Rhizoma Pinelliae, Rhizoma Arisaematis, Yi Jiyu
The alimentary toxicosis such as Eriocheir sinensiss.
Green tea (Green Tea), is the not fermented tea made, remains the natural materials of fresh leaf, the tea polyphenols that contain,
Catechin, chlorophyll, caffeine, aminoacid, vitamins and other nutritious components are also more.These natural nutrition compositions pair in green tea
Anti-aging, anti-cancer, anticancer, sterilization, antiinflammatory etc. have special-effect, are less than other teas.Folium Camelliae sinensis not only have refreshes oneself
Clear away heart-fire, clearing away summer-heat, eliminate indigestion and phlegm, go greasy fat-reducing, relieving restlessness that clears away heart-fire, removing toxic substances relieving alcoholic intoxication, promoting the production of body fluid to quench thirst, pathogenic fire reducing improving eyesight, dysentery relieving dehumidifying
Deng pharmacological action, also to modern diseases, the such as disease such as Radiation sickness, cardiovascular and cerebrovascular disease, cancer, there is certain pharmacological effect.Folium Camelliae sinensis
The Main Ingredients and Appearance with pharmacological action is tea polyphenols, caffeine, lipopolysaccharide, theanine etc..
Cortex Pini, originates as the trunk endothelium originated as the Pinus massoniana Lamb in Pinaceae pine genus plant, Pinus tabuliformiss, Pinus kesiya Royle ex Gordon var. langbianensis (A.Chev) Gaussen etc..Medicine
Material Ji Yuan is the bark for pinaceae plant Pinus kesiya Royle ex Gordon var. langbianensis (A.Chev) Gaussen, Pinus massoniana Lamb or congener.Burn and scald, infantile eczema are controlled in external.
The Radix Paeoniae Alba (scientific name：Paeonia lactiflora Pall.) it is also referred to as Paeonia sterniana Fletcher in Journ., it is Ranunculaceae Radix Paeoniae platymiscium.Its
Root can be used as medicine.Smooth liver and relieve pain, nourishing blood for regulating menstruation, astringing YIN to stop sweating.For dizziness of having a headache, hypochondriac pain, suffer from abdominal pain, limb pain twin, blood deficiency and yellow complexion,
Menoxenia, spontaneous perspiration, night sweat.
Radix Notoginseng main product, in Yunnan Wenshan Prefecture, therefore named mountain of papers Radix Notoginseng, also known as civilian state Radix Notoginseng, is panax araliaceae plant Panax
The dry root of notoginseng (Burk.) F.H.Chen and rhizome.Dissipate stasis of blood hemostasis, subduing swelling and relieving pain.For spitting blood, spit blood, nosebleed
Blood, has blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen shouting pain, tumbling and swelling.
Folium Artemisiae Argyi is the dried leaves of feverfew Chinese mugwort Artemisia argyi Levl.et Vant..Summer spends non-Kai Shicai
Pluck, remove impurity, dry.Warming the meridian for stopping bleeding, dispersing cold for relieving pain；External removing dampness to relieve itching.For spitting blood, epistaxis, metrorrhagia, menorrhagia,
Vaginal bleeding during pregnancy hematochezia, few abdomen crymodynia, coldness and unbalance in meridians, uterus cold infertile；External treatment skin pruritus.Vinegar Chinese mugwort charcoal warming the meridian for stopping bleeding, goes out for deficient cold type
Blood.
Folium Mori, scientific name：Folium Mori.Chinese medicine name, is the dried leaves of moraceae plants mulberry, and Folium Mori gently dissipate clearly, can dissipate wind
Heat.Clinic is mainly used in letting out clearly lung liver, and such as wind heat attacks lung, cough ant phlegm, or dryness-heat impairing the lung, dry cough without phlegm；And attack in wind heat
Or the disease such as flaming up of liver-fire, conjunctival congestion and swelling pain, for conventional medicine.
Camphora is branch, dry, leaf and the root of canella Camphor tree, through refining the crystalline particulate being obtained.Camphora has clearance
Key, qi stagnation removing, ward off foul, killing parasites for relieving itching, reducing swelling and alleviating pain effect, cure mainly the symptoms such as scabies prurituss, traumatic pain, toothache.
Pericarpium Citri Reticulatae Viride grass, effective ingredient has anticancer, antioxidation, repair cell, improves body immunity, the work of slow down aging
With.Because its survival rate is low, and do not possess tame condition, become rare panda type kind.
White vaseline, in addition to can making above-mentioned raw material of Chinese medicine medicine and becoming unguentum, also lubrication, moisture-keeping functions.Will be above-mentioned
It is more preferable for therapeutic effect that medicine is made for ointment, because ointment is body of paste, contacts well with skin.Vaseline is a kind of petrochemical industry
Jelly processed, is petrolatum, while vaseline can make the effective ingredient of medicine contact good with skin, will not produce and rub
Wipe, it is to avoid because leading to the necrosis of Skin Cell with skin friction, producing the phenomenon that scabs, increased the drug effect of medicine.
Compared with prior art, the invention has the advantages that：
1st, the Chinese medicinal ointment composition of the present invention is simple, and Lignum Aquilariae Resinatum plays can be with the Main Function of repair cell, with other medium-height grass
Medicine phases compatibility, rationally, prescription is precise and appropriate for compatibility, and side has heat clearing and damp drying, a removing toxic substances and promoting subsidence of swelling entirely, promoting blood circulation and stopping pain, effect of cooling blood for hemostasis,
Human body cell self-regeneration function can be promoted, protect human body from the infringement of radiation and poisonous chemical, be suitable for various areas
And patients with deep burn, quickly alleviating pain, infection, healing is fast, promotes wound surface to repair rapidly, has no toxic side effect, the wound through treatment
Face is smooth, and healing quality is good, can effectively prevent the formation of skin scar；The persistent ailments such as acute hemorrhoid are had and significantly controls curative effect
Really；To chemicotherapy dermal tissue insult, repair rapid, effect is significant；
2nd, the Chinese medicinal ointment preparation method of the present invention simple it is adaptable to commercial production.
Specific embodiment
To describe the present invention below in conjunction with specific embodiment in detail.The raw material being related in following examples or reagent are such as no special
Different explanation, derives from commercially available, the conventional behaviour that the operation employed in following examples is well known to the skilled person
Make.
Embodiment 1
The present embodiment have heat-clearing and toxic substances removing, removing heat from blood and promoting blood circulation function Chinese medicinal ointment by following weight portion crude drug prepare
And obtain：15 parts of Lignum Aquilariae Resinatum, 5 parts of Radix Ginseng, 6 parts of Herba Artemisiae Annuae, 3 parts of Rhizoma Zingiberis Recens, 2 parts of green tea, 2 parts of Cortex Pini, 3 parts of the Radix Paeoniae Alba, 2 parts of Radix Notoginseng, Folium Artemisiae Argyi 6
Part, 2 parts of Folium Mori, 2 parts of Camphora, Pericarpium Citri Reticulatae Viride grass 2 parts, 50 parts of white vaseline.
The preparation method of the Chinese medicinal ointment of the present embodiment is：Art or low-temperature extraction are distilled by prior art High Temperature High Pressure
Art, obtains the extracting solution of each crude drug, mixes, and adds white vaseline, mixes, becomes unguentum, obtain final product.
Embodiment 2
The present embodiment have heat-clearing and toxic substances removing, removing heat from blood and promoting blood circulation function Chinese medicinal ointment by following weight portion crude drug prepare
And obtain：10 parts of Lignum Aquilariae Resinatum, 4 parts of Radix Ginseng, 8 parts of Herba Artemisiae Annuae, 4 parts of Rhizoma Zingiberis Recens, 2 parts of green tea, 2 parts of Cortex Pini, 4 parts of the Radix Paeoniae Alba, 4 parts of Radix Notoginseng, Folium Artemisiae Argyi 4
Part, 2 parts of Folium Mori, 3 parts of Camphora, Pericarpium Citri Reticulatae Viride grass 3 parts, 50 parts of white vaseline.
The preparation method of the Chinese medicinal ointment of the present embodiment is with embodiment 1.
Embodiment 3
The present embodiment have heat-clearing and toxic substances removing, removing heat from blood and promoting blood circulation function Chinese medicinal ointment by following weight portion crude drug prepare
And obtain：15 parts of Lignum Aquilariae Resinatum, 6 parts of Radix Ginseng, 4 parts of Herba Artemisiae Annuae, 2 parts of Rhizoma Zingiberis Recens, 3 parts of green tea, 3 parts of Cortex Pini, 2 parts of the Radix Paeoniae Alba, 2 parts of Radix Notoginseng, Folium Artemisiae Argyi 8
Part, 3 parts of Folium Mori, 2 parts of Camphora, Pericarpium Citri Reticulatae Viride grass 2 parts, 52 parts of white vaseline.
The preparation method of the Chinese medicinal ointment of the present embodiment is with embodiment 1.
Embodiment 4
The present embodiment have heat-clearing and toxic substances removing, removing heat from blood and promoting blood circulation function Chinese medicinal ointment by following weight portion crude drug prepare
And obtain：5 parts of Lignum Aquilariae Resinatum, 2 parts of Radix Ginseng, 8 parts of Herba Artemisiae Annuae, 6 parts of Rhizoma Zingiberis Recens, 2 parts of green tea, 2 parts of Cortex Pini, 5 parts of the Radix Paeoniae Alba, 5 parts of Radix Notoginseng, 2 parts of Folium Artemisiae Argyi,
2 parts of Folium Mori, 4 parts of Camphora, Pericarpium Citri Reticulatae Viride grass 4 parts, 47 parts of white vaseline.
The preparation method of the Chinese medicinal ointment of the present embodiment is with embodiment 1.
Embodiment 5
The present embodiment have heat-clearing and toxic substances removing, removing heat from blood and promoting blood circulation function Chinese medicinal ointment by following weight portion crude drug prepare
And obtain：15 parts of Lignum Aquilariae Resinatum, 8 parts of Radix Ginseng, 3 parts of Herba Artemisiae Annuae, 2 parts of Rhizoma Zingiberis Recens, 4 parts of green tea, 4 parts of Cortex Pini, 2 parts of the Radix Paeoniae Alba, 2 parts of Radix Notoginseng, Folium Artemisiae Argyi 8
Part, 4 parts of Folium Mori, 2 parts of Camphora, Pericarpium Citri Reticulatae Viride grass 2 parts, 56 parts of white vaseline.
The preparation method of the Chinese medicinal ointment of the present embodiment is with embodiment 1.
The Chinese medicinal ointment of test example 1 embodiment of the present invention 1 is to the therapeutic effect test scalded and burn
The Chinese medicinal ointment of the embodiment of the present invention 1 is used for treatment burn overall process and has the effect that：
1. pain relieving：3-10 minute pain relieving after the drug of topical application.
2. after healing, cicatrix is few, and soft, smooth, elasticity is good, and contracture deformity seldom occurs.
3. infection, external application Chinese medicine resistance infection is strong, and a large amount of clinical cases and zoopery are confirmed.Chinese medicinal ointment is changed
Medicine puss secretions increase therewith, and lysozyme content is high, and macrophage quantity is many, and phagocytic function enlivens, and enhance the anti-of human body
Imperial ability, thus strengthen resistance infection.
4. promote the recovery of the stagnant tissue of the burned skin stasis of blood, because this medicine reduces the viscosity of blood, increase local blood
Stream, promoting the formation of wound surface hair regeneration blood vessel, thus promoting the recovery of the stagnant tissue of the burned skin stasis of blood, therefore need not make skin graft.With this
The fire victim that the Chinese medicinal ointment of inventive embodiments 1 is caused injury through thousands of a variety of causes of external application for curing, cure rate 96.4%, total effect
Rate is 100%.Shallow II degree is burnt 8 days about and is healed, deep ii degree burn healing in 18 days about, and shallow III degree burns 35 days about more
Close, the healing in undisguised 60 days about of deep muscle.
Select burn surface area to be less than 9% second degree burn patient 40, be randomly divided into 2 groups, every group 20, two groups of cases exist
Age, sex, wound area are statistically analyzed, P ＞ 0.05, no significant difference.By the Chinese medicinal ointment described in embodiment 1 and
Wound surface applies outward moist expose burn ointment (Shantou Mebo Pharmaceuticals Co., Ltd. produces, Chinese medicines quasi-word 2000004) fraction to above-mentioned two groups
Patient uses.Treatment group applies Chinese medicine ointment of the present invention, and using method is ibid；Matched group wound surface applies moist expose burn ointment outward, every 6-12
Once, remaining condition is identical for hour dressing.
Treatment standard includes：Average pain remission time, average pain extinction time, the average healing, continue to employ cicatrix
Four aspects of number of cases.4 weeks post-evaluation curative effects for the treatment of.Therapeutic effect see table：
| Group | Average pain remission time | Average pain extinction time | The average healing | Continue to employ cicatrix number of cases |
| Matched group | 3 hours | 84 hours | 21 days | 3 |
| Treatment group | 1 hour | 12 hours | 10 days | 0 |
As can be seen from the above table, treatment group is residual in pain relieving time, pain disappearing time, healing days and cicatrix
Four aspects such as number of cases are stayed to be superior to matched group it was demonstrated that the Chinese medicinal ointment treatment burn of the present invention has obvious curative effect, in addition,
Above-mentioned treatment group also has no untoward reaction.
The Chinese medicinal ointment of test example 2 embodiment of the present invention 1 is tested to the therapeutic effect of hemorrhoid
Clinical pharrnacokinetics test is carried out to the preparation of embodiments of the invention 1, result is as follows：
Patient totally 226, is randomly divided into 2 groups.In treatment group 114, man 63, female 51；16～68 years old age, averagely
38 years old age；The course of disease≤7 day 79, course of disease ＞ 7 days 35.In matched group 112, man 62, female 50；Age 18～65
Year, 37 years old mean age；The course of disease≤7 day 76, course of disease ＞ 7 days 36.Two groups of Genders, age, the course of disease, state of an illness etc. are general
Data compares that there was no significant difference (P ＞ 0.05), has comparability.
2 Therapeutic Method
Usage：This medicine external application local and injection anal canal is taken, sooner or later respectively once daily after the cleaning of local；Matched group：Matched group
Using MAYINGLONGZHICHUANGGAO (production of Wuhan Ma Yinglong Pharmaceutical), the morning and evening is each once.Above two groups all with one week for a course for the treatment of.Two groups
It is within all continuous 7 days 1 course for the treatment of.1 course for the treatment of judges curative effect after terminating.
3 observation of curative effect
3.1 criterion of therapeutical effect：Effective：Symptom is obviously improved, and anus edge swells, thrombosis mass reduction degree ＞ 2/3；Effectively：Symptom
Improve, anus edge edema, thrombosis lump absorb and reach 1/3～2/3；Invalid：Symptom is not improved, anus edge edema, the contracting of thrombosis lump
Little degree ＜ 1/3.
3.2 therapeutic outcome：See table.
| Group | Number of cases | Effective | Effectively | Invalid | Cure rate (%) | Total effective rate (%) |
| Matched group | 112 | 26 | 28 | 57 | 23.21 | 48.28 |
| Treatment group | 114 | 78 | 32 | 4 | 68.42* | 96.49* |
Note：* compare in matched group, p ＜ 0.01.
Compared with matched group, the Chinese medicinal ointment of the present invention, 68.42% is up to the cure rate of hemorrhoid, and matched group is cured
Rate only has 23.21%, and both have significant difference (p ＜ 0.01)；Total effective rate is up to 96.49%, and matched group effective percentage is only
Have both 48.28% and there is significant difference (p ＜ 0.01).
Symptom improves situation：See table
Safety observations
In treatment group 6 based on 5% ratio before the treatment after each once check, including routine blood test, hepatic and renal function all no
ANOMALOUS VARIATIONS, the no untoward reaction such as skin allergy, eczema during medication.
The clinical trial that the Chinese medicinal ointment of test example 3 embodiment of the present invention 1 is repaired to chemicotherapy dermal tissue insult
King XX, man, 63 years old, postoperative rectal cancer chemotherapy caused left bracket medicine burn necrosis, suffers from severe diabetes mellitus, hypertension.
In the hospital burn department consultation of doctors, carry out free skin grafting dermepenthesiss and transposition of flap graft failure, skin donor site and, group all downright bad by dermatotome twice
Knitting necrosis leads to wound surface to expand.Chinese medicinal ointment treatment through the embodiment of the present invention 1, through daily debridement dressing, infection, controls blood
Sugar, autologous ultra-thin skin grafting dermepenthesiss, cure discharge within 92 days.Wound surface follow-up no cicatrix protuberance, nonfunctional obstacle.
Tight XX, female, 58 years old, because of gynecological tumor operation, postoperative cause abdominal part, perineal position, both thighs portion big after radiotherapy, radiotherapy
Area ulcer, patient's height edema, dyspnea, exhaustion shape, reach large area at both thighs 1/3 from abdomen umbilical part and fester, most routed
Cave as deep as several centimeters, bosom forefinger not and bottom, through instructing the Chinese medicinal ointment using the embodiment of the present invention 1, daily dressing one
Secondary, infection supporting treatment simultaneously, wounds progressively grow healing, and edema disappears, and spirit takes a turn for the better, and treat through 50 days, patient
Healing in abdominal part many places cave, does not heal, patient can walk with descending at only one, and life can be taken care of oneself.
Embodiment described above only have expressed the several embodiments of the present invention, and its description is more concrete and detailed, but simultaneously
Therefore the restriction to the scope of the claims of the present invention can not be interpreted as.It should be pointed out that for those of ordinary skill in the art
For, without departing from the inventive concept of the premise, some deformation can also be made and improve, these broadly fall into the guarantor of the present invention
Shield scope.Therefore, the protection domain of patent of the present invention should be defined by claims.
Claims (5)
1. a kind of Chinese medicinal ointment with heat-clearing and toxic substances removing, removing heat from blood and promoting blood circulation function is it is characterised in that the activity of described Chinese medicinal ointment becomes
Divide the crude drug including following weight portion：Lignum Aquilariae Resinatum 5-15 part, Radix Ginseng 2-8 part, Herba Artemisiae Annuae 3-8 part, Rhizoma Zingiberis Recens 2-6 part, green tea 2-4 part, pine
Bark 2-4 part, Radix Paeoniae Alba 2-5 part, Radix Notoginseng 2-5 part, Folium Artemisiae Argyi 2-8 part, Folium Mori 2-4 part, Camphora 2-4 part, Pericarpium Citri Reticulatae Viride grass 2-4 part.
2. the Chinese medicinal ointment with heat-clearing and toxic substances removing, removing heat from blood and promoting blood circulation function according to claim 1 is it is characterised in that described
The active component of Chinese medicinal ointment includes the crude drug of following weight portion：Lignum Aquilariae Resinatum 10-15 part, Radix Ginseng 4-6 part, Herba Artemisiae Annuae 4-8 part, Rhizoma Zingiberis Recens 2-
4 parts, green tea 2-3 part, Cortex Pini 2-3 part, Radix Paeoniae Alba 2-4 part, Radix Notoginseng 2-4 part, Folium Artemisiae Argyi 4-8 part, Folium Mori 2-3 part, Camphora 2-3 part,
Pericarpium Citri Reticulatae Viride grass 2-3 part.
3. the Chinese medicinal ointment with heat-clearing and toxic substances removing, removing heat from blood and promoting blood circulation function according to claim 2 is it is characterised in that described
The active component of Chinese medicinal ointment includes the crude drug of following weight portion：15 parts of Lignum Aquilariae Resinatum, 5 parts of Radix Ginseng, 6 parts of Herba Artemisiae Annuae, 3 parts of Rhizoma Zingiberis Recens, green tea 2
Part, 2 parts of Cortex Pini, 3 parts of the Radix Paeoniae Alba, 2 parts of Radix Notoginseng, 6 parts of Folium Artemisiae Argyi, 2 parts of Folium Mori, 2 parts of Camphora, 2 parts of Pericarpium Citri Reticulatae Viride grass.
4. according to any one of claims 1 to 3, there is heat-clearing and toxic substances removing, the Chinese medicinal ointment of removing heat from blood and promoting blood circulation function, its feature
It is, described Chinese medicinal ointment also includes the white vaseline equal with crude drug total weight parts.
5. described in any one of Claims 1 to 4, there is heat-clearing and toxic substances removing, the preparation method of the Chinese medicinal ointment of removing heat from blood and promoting blood circulation function,
It is characterized in that, described Chinese medicinal ointment is to distill art or low-temperature extraction art by prior art High Temperature High Pressure, obtains each crude drug
Extracting solution, mix, add white vaseline, obtained from mixing.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107625683A (en) * | 2017-09-30 | 2018-01-26 | 肇庆高新区国专科技有限公司 | It is a kind of to releive and the ointment of skin care and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101332271A (en) * | 2008-08-05 | 2008-12-31 | 陈其仁 | External medicine composition for treating burn and scald |
| CN102600363A (en) * | 2012-03-15 | 2012-07-25 | 沈慰平 | Traditional Chinese compound preparation for deep burnt wound restoration and tissue and skin regeneration promotion and preparation method of traditional Chinese compound preparation |
| CN102698019A (en) * | 2012-06-21 | 2012-10-03 | 李春华 | Traditional Chinese medicine composition for curing burning and preparation method of same |
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2016
- 2016-11-02 CN CN201610981613.7A patent/CN106474439A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101332271A (en) * | 2008-08-05 | 2008-12-31 | 陈其仁 | External medicine composition for treating burn and scald |
| CN102600363A (en) * | 2012-03-15 | 2012-07-25 | 沈慰平 | Traditional Chinese compound preparation for deep burnt wound restoration and tissue and skin regeneration promotion and preparation method of traditional Chinese compound preparation |
| CN102698019A (en) * | 2012-06-21 | 2012-10-03 | 李春华 | Traditional Chinese medicine composition for curing burning and preparation method of same |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107625683A (en) * | 2017-09-30 | 2018-01-26 | 肇庆高新区国专科技有限公司 | It is a kind of to releive and the ointment of skin care and preparation method thereof |
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