CN110141636A - A kind of Chinese materia medica preparation and preparation method thereof for treating caput femoris necrosis - Google Patents
A kind of Chinese materia medica preparation and preparation method thereof for treating caput femoris necrosis Download PDFInfo
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Abstract
The present invention relates to a kind of Chinese materia medica preparation and preparation method thereof for treating caput femoris necrosis, the raw material components of the traditional Chinese powder medicine of the treatment caput femoris necrosis include 20 kinds of Chinese medicine materials such as Rhizoma Chuanxiong, the root bark of tree peony, the root bark of Chinese wolf-berry, Radix Angelicae Sinensis, Radix Angelicae Pubescentis, Cortex Eucommiae, safflower, rhizoma homalonemae, olibanum, myrrh, herba taxilli, peach kernel, Eupolyphoge sinensis, cortex acanthopanacis, Resina Draconis, native copper, the bletilla striata, radix cyathulae, full worm and centipede.Each raw material are subjected to appropriate weight proportion, using the synergistic effect between each ingredient, the Chinese materia medica preparation being finally prepared has a good effect caput femoris necrosis, and overall clinical efficacy rate reaches 80% or more.Chinese materia medica preparation compatibility of the present invention is scientific, it is significant in efficacy, take effect rapidly, and have no toxic side effect.Preparation method is simple for Chinese materia medica preparation of the present invention, mild condition and stability is good, easy to spread.
Description
Technical field
The invention belongs to technical field of Chinese medicine, and in particular to a kind of Chinese materia medica preparation for treating caput femoris necrosis and its preparation
Method.
Background technique
Caput femoris necrosis is a Pathologic process, initially occurs in the weight bearing area of femoral head, necrosis under stress
The i.e. micro- fracture of damage occurs for bone trabecular bone structure and the repair process for being then directed to injured bone.Cause the original of osteonecrosis
Because not eliminating, reparation is not perfect, and damage-reparation process continues, and leads to the change of femur header structure, collapse of femoral head, deformation, closes
Save inflammation, dysfunction.Caput femoris necrosis can no doubt cause slight illness, joint motion and walking with load dysfunction, but people are not
It to be influenced by " bad and dead " text meaning terror, caput femoris necrosis lesion is limited to after all, involves individual joints.
It is current medically to caput femoris necrosis (especially more serious situation) still without effective treatment method,
Most caput femoris necrosis is substituted for stainless steel by way of operation, and stainless steel can absorb intracorporal temperature and energy,
Topical hypothermia's situation is brought, various sequelae are caused.Meanwhile the therapeutic modality of operation belongs to trauma care, not only for patient
Huge financial burden is caused, also while bringing various infection risks.
Summary of the invention
In order to solve the above problems existing in the present technology, the present invention provides a kind of Chinese medicine systems for treating caput femoris necrosis
Agent and preparation method thereof, gained Chinese materia medica preparation have a good effect caput femoris necrosis, overall clinical efficacy rate reach 90% with
On.And Chinese materia medica preparation compatibility of the present invention it is scientific, it is significant in efficacy, take effect rapidly, and have no toxic side effect.
The technical scheme adopted by the invention is as follows:
A kind of Chinese materia medica preparation for treating caput femoris necrosis, the raw material components include:
Rhizoma Chuanxiong 20-40 parts by weight, root bark of tree peony 30-50 parts by weight, root bark of Chinese wolf-berry 15-35 parts by weight, Radix Angelicae Sinensis 20-30 parts by weight, solely
10-30 parts by weight, Cortex Eucommiae 40-60 parts by weight, safflower 15-30 parts by weight, rhizoma homalonemae 10-20 parts by weight, olibanum 15-30 weight living
Part, myrrh 15-30 parts by weight, herba taxilli 40-60 parts by weight, peach kernel 10-20 parts by weight, Eupolyphoge sinensis 20-30 parts by weight, cortex acanthopanacis
20-50 parts by weight, Resina Draconis 20-60 parts by weight, native copper 15-30 parts by weight, bletilla striata 20-40 parts by weight, radix cyathulae 15-30 weight
Measure part, full worm 10-30 parts by weight, centipede 10-30 parts by weight.
The Chinese materia medica preparation of the further preferably described treatment caput femoris necrosis, the raw material components include:
30 parts by weight of Rhizoma Chuanxiong, 40 parts by weight of the root bark of tree peony, 25 parts by weight of the root bark of Chinese wolf-berry, 25 parts by weight of Radix Angelicae Sinensis, 20 parts by weight of Radix Angelicae Pubescentis, Du
Secondary 50 parts by weight, 22.5 parts by weight of safflower, 15 parts by weight of rhizoma homalonemae, 22.5 parts by weight of olibanum, 22.5 parts by weight of myrrh, herba taxilli
50 parts by weight, 15 parts by weight of peach kernel, 25 parts by weight of Eupolyphoge sinensis, 35 parts by weight of cortex acanthopanacis, 40 parts by weight of Resina Draconis, 22.5 weight of native copper
Measure part, 30 parts by weight of the bletilla striata, 22.5 parts by weight of radix cyathulae, 20 parts by weight of full worm, 20 parts by weight of centipede.
Further, the dosage form of the Chinese materia medica preparation of the treatment caput femoris necrosis is any in powder or paste.
The preparation method of the traditional Chinese powder medicine of the treatment caput femoris necrosis, comprising the following steps:
(1) other described each raw materials in addition to herba taxilli and Cortex Eucommiae cleaned, cleaned, are dried, mixed thoroughly later with wine,
It obtains mixing liquor raw material；
(2) liquor raw material of mixing is subjected to mild fire frying, obtains raw material after wine toast；
(3) raw material nano after wine toast is crushed, raw material after being crushed；
(4) herba taxilli and Cortex Eucommiae successively cleaned respectively, cleaned, dried；Be added distilled water decocted, filtered,
Gained concentrate is carried out alcohol precipitation, respectively obtains herba taxilli sediment and Cortex Eucommiae sediment by concentration；Gained sediment is sprayed
Mist is dry, crushes, and respectively obtains Viscum album extract and eucommia ulmoides extracts；
(5) raw material and step (4) middle gained Viscum album extract and eucommia ulmoides extracts are mixed after crushing gained in step (3)
It closes uniformly to get the traditional Chinese powder medicine for arriving the treatment caput femoris necrosis.
Further, in step (1), the wine of selection is the white wine that Alcohol degree is 52%Vol-63%Vol；The raw material
Mass ratio with alcohol is 10:(1-2).
Further, in step (3), the smashed partial size of raw material is 20-100nm.
Further, in step (4), the additional amount of the distilled water is 4-6 times of each raw material traditional Chinese medicine quality, the decoction
Time is 1.5-2h, and the alcohol precipitation time is 3-5h.
Further, instructions of taking be it is adult once a day, each 10-20g takes medicine after meal, warm water delivery service；The outer used time
This powder is reconciled with water, spreads on affected part, twice daily.
The preparation method of the Chinese medicinal ointment of the treatment caput femoris necrosis, comprising the following steps:
(1) each raw material cleaned, cleaned, crushed, be uniformly mixed, steamed after adding soaking in Chinese liquor, then
Distiller's yeast is added to ferment, obtains fermentation material；
(2) fermentation material is distilled, distillating extracting liquid is condensed into cream, obtain the treatment caput femoris necrosis
Chinese medicinal ointment.
Further, in step (1), it is 80-120 mesh that each raw material, which is crushed to partial size, and the temperature of the immersion is 25-
28 DEG C, the time of the immersion is 6-8 days, and the Alcohol degree of the white wine is 50-65 degree.
Further, in step (1), the temperature steamed is 120-200 DEG C, and the time steamed is 60-90 points
Clock, the additive amount of the distiller's yeast are the 1-3wt% of the raw material gross weight, and the fermentation time is 30-60 days, the temperature of the fermentation
Degree is 25-28 DEG C.
Further, in step (2), by distillating extracting liquid mild fire infusion 1-2h after being boiled by fire.
Further, external application method is that this cream is applied directly to affected part, can be relieved pain within 1 hour or so.
It underdraws below to effect caused by raw material in the present invention.
Rhizoma Chuanxiong, acrid flavour are warm-natured；Return liver, gallbladder channel.Effect: promote breath and open depression dispels that wind-dryness is wet, promoting blood circulation and stopping pain, controls air-cooled
Headache rotation is dizzy, hypochondriac pain abdomen pain, arthritis muscle contraction, menostasis, difficult labour, postpartum stasis block pain, ulcer sores, irregular menstruation, amenorrhea and algomenorrhea,
Lump in the abdomen abdominal pain, pricking pain in the chest, tumbling and swelling, headache, rheumatic arthralgia.
The root bark of tree peony, bitter, pungent, cold nature；Thoughts of returning home warp, Liver Channel, kidney channel.Effect: clearing heat and cooling blood, activating microcirculation and removing stasis medicinal, with controlling
Febrile virulent maculae, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to yin, amenorrhea and algomenorrhea, carbuncle sore tumefacting virus, injuries from falls as well.
The root bark of Chinese wolf-berry, it is sweet in flavor, it is cold in nature；Return lung, liver and kidney channel.Effect: cool blood is except steaming, clearing lung-heat fall fire, for deficiency of Yin tide
Heat, hectic fever due to yin night sweat, cough with lung heat, hemoptysis, bleeding from five sense organs or subcutaneous tissue, Heat Diabetes.
Radix Angelicae Sinensis, it is sweet in flavor, pungent, it is warm-natured；Return liver, the heart, the spleen channel.Effect: have replenishing and activating blood, menstruction regulating and pain relieving, ease constipation logical
Just the effect of, is usually used in blood deficiency chlorosis, dizziness palpitaition, irregular menstruation, amenorrhea and algomenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, falls and flutter damage
Wound, ulcer sores, dry constipation of intestines.
Radix Angelicae Pubescentis, acrid flavour, hardship, slightly warm in nature；Return kidney channel, bladder meridian.Effect: dispelling wind and eliminating dampness, numbness relieving and pain relieving, with controlling chill
Wet pain, lumbocrural pain, few the moon volt wind headache.
Cortex Eucommiae, it is sweet in flavor, it is warm-natured；Return liver warp, kidney channel.Effect: nourishing liver and kidney, strengthening the bones and muscles, miscarriage prevention, with control lumbago due to the kidney deficiency,
Muscles and bones inability, blood leaking in gestation, threatened abortion, vascular hypertension.
Safflower, acrid flavour are warm-natured；Converge to heart and liver channels.Effect: blood circulation, stasis eliminatings analgesic, controlling through closing, abdominal mass, difficult labour,
Stillborn foetus, disease that postpartum lochia can't go, hemostasis are had a pain, carbuncle swells, injury from falling down.
Rhizoma homalonemae, it is bitter, pungent, it is warm-natured；Return liver and kidney channel.Effect: wind-damp dispelling, muscle reinforcing and bone strengthening, promoting blood circulation and stopping pain are used for wind
Cold-dampness numbness, waist and knee crymodynia, lower limb contraction.
Olibanum, acrid flavour, hardship are warm-natured；Thoughts of returning home warp, the spleen channel, Liver Channel.Effect: regulating qi and activating blood, analgesic therapy, detumescence, myogenic,
With controlling stagnation of QI-blood, trusted subordinate's pain, ulcerative carbuncle pyogenic infections, traumatic injury, rheumatic arthralgia, dysmenorrhea, postpartum blood stasis stabbing pain.Clinic is also used to
Treat acute appendicitis.
Myrrh, acrid flavour, hardship are mild-natured；Return heart, liver, the spleen channel.Effect: having the effect of scattered stasis pain, detumescence and promoting granulation,
It is usually used in chest impediment and cardialgia, gastral cavity pain, dysmenorrhea menostasis, postpartum stasis, abdominal mass and abdominal pain, rheumatic arthralgia, traumatic injury, carbuncle swells sore
Etc. illnesss treatment.
Herba taxilli, it is bitter, sweet, it is mild-natured；Return liver warp, kidney channel.Effect: nourishing liver and kidney, strengthening the bones and muscles, wind-damp dispelling, miscarriage prevention member,
With controlling, rheumatic arthralgia, soreness and weakness of waist and knees, muscles and bones be powerless, metrorrhagia and metrostaxis pass through more, blood leaking in gestation, threatened abortion, hypertension.
Peach kernel, it is bitter, sweet, it is mild-natured；Return heart, liver, large intestine channel.Effect: promoting blood circulation, removing blood stasis, moistening intestines and relaxing bowels, for menostasis,
Dysmenorrhea, wei lump in the abdomen lump in the abdomen, traumatic injury, intestinal dryness and constipation.
Eupolyphoge sinensis belongs to Blattaria ground Corydiidae, and taste is salty, cold in nature；It is slightly poisonous, return liver warp.Effect: there is broken stasis of blood blood, continue
The effect of muscles and bones, is used for injured bone, blood stasis closed, abdominal mass lump in the abdomen.
Cortex acanthopanacis, acrid flavour, hardship are warm-natured；Return liver warp, kidney channel.Effect: wind-damp dispelling, nourishing liver and kidney, strengthening the bones and muscles, with controlling wind
Arthritis with fixed pain caused by dampness pain, muscles and bones impotence, children's retardation of walking, asthenia, oedema, tinea pedis.
Resina Draconis, it is sweet in flavor, salty, it is warm-natured, flat, it is nontoxic；Return lung, spleen, kidney three pass through.Effect: promoting blood circulation to remove blood stasis, analgesic therapy it
Blood, expelling pus and promoting granulation are had a pain for traumatic injury, hemostasis, women's qi and blood stagnation, traumatic hemorrhage, running sore do not close up long and chronic
The diseases such as abdominal pain caused by colitis, diarrhea.
Native copper, the general Chinese medicine name of the field of Chinese medicines are sulfide-based mineral pyrite race pyrite, main to contain ferrous disulfide
(FeS2), there is the effect of removing blood stasis and acesodyne, reunion of fractured tendons and bones.For traumatic injury, injured bone, pain caused by ecchymoma.
The bletilla striata, bitter, sweet, puckery, cold nature；Return lung, liver, stomach meridian.Effect: astringing to arrest bleeding, detumescence and promoting granulation are used for cough
Blood haematemesis, traumatic hemorrhage, sore swollen toxin, chapped skin, pulmonary tuberculosis hemoptysis, ulcer haemorrhage.
Radix cyathulae, sweet in flavor, slight bitter are mild-natured；Return liver warp, kidney channel.Effect: dispelling stasis of blood and stimulating the menstrual flow, easing joint movement, diuresis is logical
Leaching, with treating rheumatic lumbocrural pain, foot impotence muscle contraction, blood strangury, urine leaching, hematuria, women's menostasis, lump in the abdomen lump in the abdomen.
Full worm, acrid flavour is mild-natured, toxic, return liver warp.Effect: relieve the wind syndrome antispastic, is removed obstruction in channels to relieve pain at dispersing pathogen accumulation, for small
Youngster's infantile convulsion, twitch spasm, middle air port be askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, sore, scrofula.
Centipede, acrid flavour is warm-natured, toxic；Return liver warp.Effect: relieve the wind syndrome antispastic, is removed obstruction in channels to relieve pain at function poison dissipating bind, for small
Youngster's infantile convulsion, twitch spasm, middle air port be askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, sore, scrofula, venomous snake bite.
Gamboge, it is sour, puckery, it is cool in nature.Effect: reduce swelling, attack poison, dispel rotten sore, hemostasis, desinsection, for swollen ulcer drug,
Ulcer, wet sore, tumour, stubborn dermatitis, treating swelling and pain by traumatic injury, sore hurt bleeding and scald.
Asafoetide, it is bitter, pungent, it is warm-natured；Returns spleen, stomach meridian.Effect: disperse accumulation dissipates ruffian, desinsection, is used for meat stagnation, hemostasis
Abdominal mass, mass in abdomen, abdominal pain due to enterositosis.
Bush, it is sweet in flavor, salty, it is mild-natured；Thoughts of returning home warp, Liver Channel, the spleen channel.Effect: promoting circulation of blood dissolving stasis, swelling and pain relieving are fallen with controlling
Play damage, the fracture injury of tendon and muscle, the stagnant swelling and pain of the stasis of blood, amenorrhea and algomenorrhea, postpartum stasis, chest and abdomen shouting pain, ulcer sore pain.
Ramulus mori, mild-natured, bitter；Return liver warp.Effect: wind-damp dispelling, degrading the channel, row aqueous vapor cure mainly rheumatic arthralgia, apoplexy
Hemiplegia, oedema tinea pedis, human body pruritus.
Lopseed, warm-natured, acrid flavour；Return kidney channel, Liver Channel.Effect: dispelling wind and eliminating dampness, relaxing tendons and activating collaterals, eliminating stasis to subdue swelling, removing toxic substances
Analgesic, cures mainly rheumatic arthralgia, muscles and bones contracture, the disturbance of lower legs due to pathogenic cold and dampness, lumbar strain, paralysis, amenorrhoea, eczema of scrotum, sore furuncle poison.
Lycopodium calvatum, it is warm-natured, it is mildly bitter flavor, pungent；Return liver warp, the spleen channel, kidney channel.Effect: cold-dispelling, dehumidification swelling, relaxing muscles and tendons
It is active, it is used for treating arthralgia due to cold and dampness, joint pain, numbness of skin, tetraparesis, oedema, traumatic injury.
Radix Aconiti, effect: dispelling wind and eliminating dampness, antalgic are used for treating arthralgia due to cold and dampness, arthralgia, trusted subordinate's crymodynia, cold hernia
Have a pain, the illnesss such as treatment wind-cold-dampness arthralgia, arthralgia.
Radix Aconiti Kusnezoffii, acrid flavour, hardship, property heat；It is very toxic；Return heart, liver,kidney,spleen warp.Effect: dispelling wind and eliminating dampness, Wen Jingzhi
Bitterly, it is used for treating arthralgia due to cold and dampness, arthralgia, trusted subordinate's crymodynia, cold hernia are had a pain, narcotic analgesic.
Arisacma consanguineum schott, it is bitter, pungent, it is warm-natured, it is toxic.Effect: eliminating dampness and eliminating phlegm, expelling wind and relieving convulsion, mass dissipating and swelling eliminating are used for chronic phlegm
Cough, anemophlegmatic vertigo, heap soil or fertilizer over and around the roots of apoplexy phlegm, facial paralysis, hemiplegia, epilepsy, infantile convulsion, tetanus.
Semen brassicae, acrid flavour is warm-natured, nontoxic；Return lung, stomach two pass through.Effect: promoting circulation of qi and eliminating phlegm, warming spleen and stomach for dispelling cold, dredging collateral stop
Bitterly, phlegm retention cough and asthma, fullness in chest and hypochondrium pain, gastric disorder causing nausea vomiting, aphasia from apoplexy, limbs numbness pain numbness, tinea pedis, negative subcutaneous ulcer, pyogenic infections, bruise are controlled
Swelling and pain.
Rhizoma typhonii, warm-natured, acrid flavour are toxic；Return stomach meridian, Liver Channel.Effect: wind-dispelling phlegm, arresting convulsion jerk, detoxify, dissipating bind, stopping
Bitterly, with controlling the puckery stuttering, phlegm and headache of heap soil or fertilizer over and around the roots of apoplexy phlegm, facial paralysis, language, migraine and general headache, larynx numbness pharyngalgia, tetanus, control scrofula outside
Subcutaneous nodule, venomous snake bite.
The rhizome of davallia, warm-natured, bitter, return liver warp, kidney channel.Effect: continues and hinders pain relieving, The strong bone of kidney tonifying, with control lumbago due to the kidney deficiency,
Toothache, tinnitus, chronic diarrhea, traumatic injury, alopecia areata, corn etc..
Rhizoma curcumae longae concisa, warm-natured, acrid flavour, hardship；Converge to the spleen channel, Liver Channel.Effect: it is breaking blood and promoting the circulation of qi, inducing meastruation to relieve menalgia, with controlling stasis warp
It closes, menalgia, pricking pain in the chest, rheumatic arthralgia, shoulder arm pain, traumatic injury.
The wooden small pin for the case, bitter, micro-sweet are warm-natured, toxic；Return liver, spleen, stomach meridian.Effect: dissipating bind detumescence, is relieved pain, is chased after poison,
Control carbuncle swells, furunculosis, acute mastitis, scrofula, hemorrhoid gall, chronic eczema, psoriasis, the favus of the scalp, bruise blood stasis and swelling pain.
HERBA ASARI from Liaoning of China, acrid flavour is warm-natured, mild toxicity；Return lung, kidney, the heart channel of Hang-Shaoyin.Effect: cold dispelling wind-dispelling, warming lung and resolving fluid, is led at analgesic
Key cures mainly exterior syndrome due to wind-cold, headache, toothache, rheumatic arthralgia, phlegm retention cough and asthma, nasal obstruction, nasosinusitis, aphtha.
Leech, mild-natured, taste is salty, bitter, slightly poisonous；Return liver warp.Effect: blood-breaking, by the stasis of blood, promoting menstruation, Yong Zhi abdominal mass and lump,
Blood stasis amenorrhoea, traumatic injury.
Raw cape jasmine, cold in nature, bitter；Thoughts of returning home warp, lung channel, tri-jiao channel.Effect: purging intense heat relieving restlessness, reducing fever and causing diuresis, cool blood solution
Poison, externally used detumescence analgesic, with controlling, the strongly fragrant ambition of warm disease heat, vexed, gloomy, dysphoria be peaceful, sleep disorder, liver and gallbladder damp-heat pent-up, Huang
Subcutaneous ulcer, fever, scanty drak urine, the haematemesis of blood-heat bleeding, bleeding from five sense organs or subcutaneous tissue, hematuria, traumatic injury, scald, burn etc..
Radix dipsaci, effect: blood vessels, continuous injured, only metrorrhagia and metrostaxis are adjusted in nourishing liver and kidney, strengthening the bones and muscles, are used for aching pain in waist and back, podomere impotence
Numbness falls and flutters wound, damage muscle folding bone, movement of the foetus leakage red, metrorrhagia, spermatorrhea, leukorrhagia, ulcer sore swells.
Moschus, warm-natured, acrid flavour, thoughts of returning home warp, the spleen channel.Effect: inducing resuscitation of having one's ideas straightened out, blood circulation, swelling and pain relieving, with controlling heat
Sick coma, apoplexy coma due to blocking of the respiratory system, bstruction of the circulation of vital energy is fainted cruelly, middle evil is gone into a coma, menostasis, Disorder lump in the abdomen, difficult labour stillborn foetus, trusted subordinate sudden and violent pain, carbuncle swells scrofula, throat are swollen
Bitterly, injury from falling down, numbness pain are numb.
Camphor, property heat, acrid flavour are toxic；Thoughts of returning home warp, the spleen channel.Effect: having one's ideas straightened out and ward off dirty, dehumidifying desinsection, warming and odynolysis,
The bored unrest of the abdominal pain caused by the heresy for controlling erputive abdominal disease, summer-heat and damp, fever and chills, vomiting and diarrhoea, scabies wet sore, itch are festered.
The invention has the benefit that
It is of the present invention treatment caput femoris necrosis traditional Chinese powder medicine raw material components include Rhizoma Chuanxiong, the root bark of tree peony, the root bark of Chinese wolf-berry, when
Return, is Radix Angelicae Pubescentis, Cortex Eucommiae, safflower, rhizoma homalonemae, olibanum, myrrh, herba taxilli, peach kernel, Eupolyphoge sinensis, cortex acanthopanacis, Resina Draconis, native copper, white
20 kinds of Chinese medicine materials such as splendid achnatherum, radix cyathulae, full worm and centipede.Each raw material are subjected to appropriate weight proportion, using between each ingredient
Synergistic effect, the Chinese materia medica preparation being finally prepared have a good effect caput femoris necrosis, and overall clinical efficacy rate reaches
80% or more.Chinese materia medica preparation compatibility of the present invention is scientific, it is significant in efficacy, take effect rapidly, and have no toxic side effect.It is of the present invention
Preparation method is simple for Chinese materia medica preparation, mild condition and stability is good, easy to spread.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical solution of the present invention will be carried out below
Detailed description.Obviously, described embodiment is only a part of the embodiments of the present invention, instead of all the embodiments.
Based on the embodiments of the present invention, those of ordinary skill in the art obtained institute without making creative work
There is other embodiment, belongs to the range that the present invention is protected.
1g is represented in following example with 1 parts by weight.
Embodiment 1
The present embodiment provides a kind of traditional Chinese powder medicine for treating caput femoris necrosis, raw material components include:
20 parts by weight of Rhizoma Chuanxiong, 30 parts by weight of the root bark of tree peony, 15 parts by weight of the root bark of Chinese wolf-berry, 20 parts by weight of Radix Angelicae Sinensis, 10 parts by weight of Radix Angelicae Pubescentis, Du
Secondary 40 parts by weight, 15 parts by weight of safflower, 10 parts by weight of rhizoma homalonemae, 15 parts by weight of olibanum, 15 parts by weight of myrrh, 40 weight of herba taxilli
It is part, 10 parts by weight of peach kernel, 20 parts by weight of Eupolyphoge sinensis, 20 parts by weight of cortex acanthopanacis, 20 parts by weight of Resina Draconis, 15 parts by weight of native copper, white
20 parts by weight of splendid achnatherum, 15 parts by weight of radix cyathulae, 10 parts by weight of full worm, 10 parts by weight of centipede.
The preparation method of the traditional Chinese powder medicine of the treatment caput femoris necrosis, comprising the following steps:
(1) each raw material in addition to herba taxilli and Cortex Eucommiae cleaned, cleaned, dried, be with Alcohol degree later
The white wine of 52%Vol is mixed thoroughly, and the mass ratio of the raw material and white wine is 10:1, obtains mixing liquor raw material；
(2) the liquor raw material mild fire frying color of mixing is obtained into raw material after wine toast to intensification；
(3) it is 20nm, raw material after being crushed that raw material nano, which is crushed to partial size, after processing wine；
(4) herba taxilli and Cortex Eucommiae successively cleaned respectively, cleaned, dried；The steaming of 4 times of each raw material traditional Chinese medicine quality is added
Distilled water decocts 1.5h, and filtering, concentration by gained concentrate alcohol precipitation 3h, respectively obtain herba taxilli sediment and Cortex Eucommiae sediment；It will
Gained sediment is spray-dried, is crushed, and Viscum album extract and eucommia ulmoides extracts are respectively obtained；
(5) raw material and step (4) middle gained Viscum album extract and eucommia ulmoides extracts are mixed after crushing gained in step (3)
It closes uniformly to get the traditional Chinese powder medicine for arriving the treatment caput femoris necrosis.
Embodiment 2
The present embodiment provides a kind of traditional Chinese powder medicine for treating caput femoris necrosis, raw material components include:
40 parts by weight of Rhizoma Chuanxiong, 50 parts by weight of the root bark of tree peony, 35 parts by weight of the root bark of Chinese wolf-berry, 30 parts by weight of Radix Angelicae Sinensis, 30 parts by weight of Radix Angelicae Pubescentis, Du
Secondary 60 parts by weight, 30 parts by weight of safflower, 20 parts by weight of rhizoma homalonemae, 30 parts by weight of olibanum, 30 parts by weight of myrrh, 60 weight of herba taxilli
It is part, 20 parts by weight of peach kernel, 30 parts by weight of Eupolyphoge sinensis, 50 parts by weight of cortex acanthopanacis, 60 parts by weight of Resina Draconis, 30 parts by weight of native copper, white
40 parts by weight of splendid achnatherum, 30 parts by weight of radix cyathulae, 30 parts by weight of full worm, 30 parts by weight of centipede.
The preparation method of the traditional Chinese powder medicine of the treatment caput femoris necrosis, comprising the following steps:
(1) each raw material in addition to herba taxilli and Cortex Eucommiae cleaned, cleaned, dried, be with Alcohol degree later
The white wine of 63%Vol is mixed thoroughly, and the mass ratio of the raw material and white wine is 10:2, obtains mixing liquor raw material；
(2) the liquor raw material mild fire frying color of mixing is obtained into raw material after wine toast to intensification；
(3) it is 100nm, raw material after being crushed that raw material nano, which is crushed to partial size, after processing wine；
(4) herba taxilli and Cortex Eucommiae successively cleaned respectively, cleaned, dried；The steaming of 6 times of each raw material traditional Chinese medicine quality is added
Distilled water decocts 2h, and filtering, concentration by gained concentrate alcohol precipitation 5h, respectively obtain herba taxilli sediment and Cortex Eucommiae sediment；By institute
It obtains sediment to be spray-dried, crushed, respectively obtains Viscum album extract and eucommia ulmoides extracts；
(5) raw material and step (4) middle gained Viscum album extract and eucommia ulmoides extracts are mixed after crushing gained in step (3)
It closes uniformly to get the traditional Chinese powder medicine for arriving the treatment caput femoris necrosis.
Embodiment 3
The present embodiment provides a kind of traditional Chinese powder medicine for treating caput femoris necrosis, raw material components include:
30 parts by weight of Rhizoma Chuanxiong, 40 parts by weight of the root bark of tree peony, 25 parts by weight of the root bark of Chinese wolf-berry, 25 parts by weight of Radix Angelicae Sinensis, 20 parts by weight of Radix Angelicae Pubescentis, Du
Secondary 50 parts by weight, 22.5 parts by weight of safflower, 15 parts by weight of rhizoma homalonemae, 22.5 parts by weight of olibanum, 22.5 parts by weight of myrrh, herba taxilli
50 parts by weight, 15 parts by weight of peach kernel, 25 parts by weight of Eupolyphoge sinensis, 35 parts by weight of cortex acanthopanacis, 40 parts by weight of Resina Draconis, 22.5 weight of native copper
Measure part, 30 parts by weight of the bletilla striata, 22.5 parts by weight of radix cyathulae, 20 parts by weight of full worm, 20 parts by weight of centipede.
The preparation method of the traditional Chinese powder medicine of the treatment caput femoris necrosis, comprising the following steps:
(1) each raw material in addition to herba taxilli and Cortex Eucommiae cleaned, cleaned, dried, be with Alcohol degree later
The white wine of 60%Vol is mixed thoroughly, and the mass ratio of the raw material and white wine is 20:3, obtains mixing liquor raw material；
(2) the liquor raw material mild fire frying color of mixing is obtained into raw material after wine toast to intensification；
(3) it is 60nm, raw material after being crushed that raw material nano, which is crushed to partial size, after processing wine；
(4) herba taxilli and Cortex Eucommiae successively cleaned respectively, cleaned, dried；The steaming of 5 times of each raw material traditional Chinese medicine quality is added
Distilled water decocts 1.75h, and filtering, concentration by gained concentrate alcohol precipitation 4h, respectively obtain herba taxilli sediment and Cortex Eucommiae sediment；
Gained sediment is spray-dried, is crushed, Viscum album extract and eucommia ulmoides extracts are respectively obtained；
(5) raw material and step (4) middle gained Viscum album extract and eucommia ulmoides extracts are mixed after crushing gained in step (3)
It closes uniformly to get the traditional Chinese powder medicine for arriving the treatment caput femoris necrosis.
Embodiment 4
The present embodiment provides a kind of Chinese medicinal ointment for treating caput femoris necrosis, raw material components include:
20 parts by weight of Rhizoma Chuanxiong, 30 parts by weight of the root bark of tree peony, 15 parts by weight of the root bark of Chinese wolf-berry, 20 parts by weight of Radix Angelicae Sinensis, 10 parts by weight of Radix Angelicae Pubescentis, Du
Secondary 40 parts by weight, 15 parts by weight of safflower, 10 parts by weight of rhizoma homalonemae, 15 parts by weight of olibanum, 15 parts by weight of myrrh, 40 weight of herba taxilli
It is part, 10 parts by weight of peach kernel, 20 parts by weight of Eupolyphoge sinensis, 20 parts by weight of cortex acanthopanacis, 20 parts by weight of Resina Draconis, 15 parts by weight of native copper, white
20 parts by weight of splendid achnatherum, 15 parts by weight of radix cyathulae, 10 parts by weight of full worm, 10 parts by weight of centipede.
The preparation method of the Chinese medicinal ointment of the treatment caput femoris necrosis, comprising the following steps:
(1) each raw material cleaned, cleaned, being crushed to partial size is 80 mesh, is uniformly mixed, adds 50 degree of white wine 25
It is steamed 60 minutes after being impregnated 6 days at DEG C, the temperature steamed is 120 DEG C, and the distiller's yeast fermentation 30 of raw material gross weight 1wt% is then added
It, the temperature of fermentation is 25 DEG C, obtains fermentation material；
(2) fermentation material is distilled, mild fire infusion 1h after distillating extracting liquid is boiled by fire is condensed into cream, obtains
To the bone-knitting Chinese medicament paste.
Embodiment 5
The present embodiment provides a kind of Chinese medicinal ointment for treating caput femoris necrosis, raw material components include:
40 parts by weight of Rhizoma Chuanxiong, 50 parts by weight of the root bark of tree peony, 35 parts by weight of the root bark of Chinese wolf-berry, 30 parts by weight of Radix Angelicae Sinensis, 30 parts by weight of Radix Angelicae Pubescentis, Du
Secondary 60 parts by weight, 30 parts by weight of safflower, 20 parts by weight of rhizoma homalonemae, 30 parts by weight of olibanum, 30 parts by weight of myrrh, 60 weight of herba taxilli
It is part, 20 parts by weight of peach kernel, 30 parts by weight of Eupolyphoge sinensis, 50 parts by weight of cortex acanthopanacis, 60 parts by weight of Resina Draconis, 30 parts by weight of native copper, white
40 parts by weight of splendid achnatherum, 30 parts by weight of radix cyathulae, 30 parts by weight of full worm, 30 parts by weight of centipede.
The preparation method of the Chinese medicinal ointment of the treatment caput femoris necrosis, comprising the following steps:
(1) each raw material cleaned, cleaned, being crushed to partial size is 120 mesh, is uniformly mixed, 65 degree of white wine is added to exist
It is steamed 90 minutes after being impregnated 8 days at 28 DEG C, the temperature steamed is 200 DEG C, and the distiller's yeast fermentation 60 of raw material gross weight 3wt% is then added
It, the temperature of fermentation is 28 DEG C, obtains fermentation material；
(2) fermentation material is distilled, mild fire infusion 2h after distillating extracting liquid is boiled by fire is condensed into cream, obtains
To the bone-knitting Chinese medicament paste.
Embodiment 6
The present embodiment provides a kind of Chinese medicinal ointment for treating caput femoris necrosis, raw material components include:
30 parts by weight of Rhizoma Chuanxiong, 40 parts by weight of the root bark of tree peony, 25 parts by weight of the root bark of Chinese wolf-berry, 25 parts by weight of Radix Angelicae Sinensis, 20 parts by weight of Radix Angelicae Pubescentis, Du
Secondary 50 parts by weight, 22.5 parts by weight of safflower, 15 parts by weight of rhizoma homalonemae, 22.5 parts by weight of olibanum, 22.5 parts by weight of myrrh, herba taxilli
50 parts by weight, 15 parts by weight of peach kernel, 25 parts by weight of Eupolyphoge sinensis, 35 parts by weight of cortex acanthopanacis, 40 parts by weight of Resina Draconis, 22.5 weight of native copper
Measure part, 30 parts by weight of the bletilla striata, 22.5 parts by weight of radix cyathulae, 20 parts by weight of full worm, 20 parts by weight of centipede.
The preparation method of the Chinese medicinal ointment of the treatment caput femoris necrosis, comprising the following steps:
(1) each raw material cleaned, cleaned, being crushed to partial size is 80-120 mesh, is uniformly mixed, adds 58 degree of white wine
It is steamed 70 minutes after being impregnated 7 days at 26.5 DEG C, the temperature steamed is 160 DEG C, and the distiller's yeast hair of raw material gross weight 2wt% is then added
Ferment 45 days, the temperature of fermentation was 26.5 DEG C, obtained fermentation material；
(2) fermentation material being distilled, mild fire infusion 1.5h after distillating extracting liquid is boiled by fire is condensed into cream,
Obtain the bone-knitting Chinese medicament paste.
Comparative example 1
The difference of this comparative example and embodiment 3 is only that raw material components, the raw material components of this comparative example do not include Cortex Eucommiae, mulberry
Parasitic and Rhizoma Chuanxiong, other are same as Example 3.
Comparative example 2
The difference of this comparative example and embodiment 6 is only that raw material components, the raw material components of this comparative example do not include the root bark of Chinese wolf-berry,
The bletilla striata and myrrh, other are same as Example 6.
Comparative example 3
The difference of this comparative example and embodiment 6 is only that preparation method, this comparative example preparation method step are as follows:
(1) each raw material being cleaned, is cleaned, the pure water that 3 times of quality are added impregnates 2h, and high fire decocts 5min,
Then turn to be cooked by slow fire 90min, filtrate is obtained by filtration using 600 mesh filter screens；
(2) by the filtrate temperature be 40 DEG C at be condensed into cream, obtain it is described treatment caput femoris necrosis Chinese medicinal ointment.
Experimental example
One, effect test is carried out to the Chinese materia medica preparation for the treatment of caput femoris necrosis obtained by embodiment 1-6 and comparative example 1-3
1, subjects: Patients with Aseptic Necrosis of Femoral 117,9 groups are randomly divided into, respectively corresponds embodiment 1-6 and comparative example
1-3。
2, it tests process: subject being allowed to smear the Chinese medicine system for the treatment of caput femoris necrosis obtained by embodiment 1-6 and comparative example 1-3
Agent 20 days, then inquire subject's using effect.
3, test result judgment criteria: (1) effectively: caput femoris necrosis symptom disappears, no longer pain；(2) effective: femoral head
Downright bad symptom makes moderate progress, pain relief；(3) invalid: caput femoris necrosis symptom does not improve, and pain does not mitigate.
4, test result: it is shown in Table 1.
Table 1- test result
| Group | Number | Effectively | It is effective | In vain | Efficient (%) |
| Embodiment 1 | 13 | 9 | 3 | 1 | 92.3 |
| Embodiment 2 | 13 | 5 | 6 | 2 | 84.6 |
| Embodiment 3 | 13 | 10 | 2 | 1 | 92.3 |
| Embodiment 4 | 13 | 6 | 5 | 2 | 84.6 |
| Embodiment 5 | 13 | 8 | 4 | 1 | 92.3 |
| Embodiment 6 | 13 | 9 | 4 | 0 | 100 |
| Comparative example 1 | 13 | 2 | 3 | 8 | 38.5 |
| Comparative example 2 | 13 | 3 | 4 | 6 | 53.8 |
| Comparative example 3 | 13 | 1 | 5 | 7 | 46.2 |
From table 1 it follows that stock of the Chinese materia medica preparation for the treatment of caput femoris necrosis obtained by 1-6 of the embodiment of the present invention to patient
Head necrosis symptom has good therapeutic effect, and effective percentage reaches 80% or more, hence it is evident that it is bad to be higher than treatment femoral head obtained by comparative example 1-3
Dead Chinese materia medica preparation also sufficiently confirms Chinese materia medica preparation of the present invention to the curative effect of caput femoris necrosis.
The above description is merely a specific embodiment, but scope of protection of the present invention is not limited thereto, any
Those familiar with the art in the technical scope disclosed by the present invention, can easily think of the change or the replacement, and should all contain
Lid is within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of Chinese materia medica preparation for treating caput femoris necrosis, which is characterized in that the raw material components include:
Rhizoma Chuanxiong 20-40 parts by weight, root bark of tree peony 30-50 parts by weight, root bark of Chinese wolf-berry 15-35 parts by weight, Radix Angelicae Sinensis 20-30 parts by weight, Radix Angelicae Pubescentis 10-
30 parts by weight, safflower 15-30 parts by weight, rhizoma homalonemae 10-20 parts by weight, olibanum 15-30 parts by weight, do not have Cortex Eucommiae 40-60 parts by weight
Medicine 15-30 parts by weight, herba taxilli 40-60 parts by weight, peach kernel 10-20 parts by weight, Eupolyphoge sinensis 20-30 parts by weight, cortex acanthopanacis 20-50 weight
Measure part, Resina Draconis 20-60 parts by weight, native copper 15-30 parts by weight, bletilla striata 20-40 parts by weight, radix cyathulae 15-30 parts by weight, complete
Worm 10-30 parts by weight, centipede 10-30 parts by weight.
2. the Chinese materia medica preparation for the treatment of caput femoris necrosis according to claim 1, which is characterized in that the raw material components packet
It includes:
30 parts by weight of Rhizoma Chuanxiong, 40 parts by weight of the root bark of tree peony, 25 parts by weight of the root bark of Chinese wolf-berry, 25 parts by weight of Radix Angelicae Sinensis, 20 parts by weight of Radix Angelicae Pubescentis, Cortex Eucommiae 50
Parts by weight, 22.5 parts by weight of safflower, 15 parts by weight of rhizoma homalonemae, 22.5 parts by weight of olibanum, 22.5 parts by weight of myrrh, 50 weight of herba taxilli
Measure part, 15 parts by weight of peach kernel, 25 parts by weight of Eupolyphoge sinensis, 35 parts by weight of cortex acanthopanacis, 40 parts by weight of Resina Draconis, 22.5 weight of native copper
Part, 30 parts by weight of the bletilla striata, 22.5 parts by weight of radix cyathulae, 20 parts by weight of full worm, 20 parts by weight of centipede.
3. the Chinese materia medica preparation of any one of -2 treatment caput femoris necrosis according to claim 1, which is characterized in that the treatment stock
The dosage form of the Chinese materia medica preparation of head necrosis is any in powder or paste.
4. a kind of preparation method of the traditional Chinese powder medicine of the treatment caput femoris necrosis, which comprises the following steps:
(1) other described each raw materials in addition to herba taxilli and Cortex Eucommiae cleaned, cleaned, dried, mixed thoroughly, obtain with wine later
Mix liquor raw material；
(2) liquor raw material of mixing is subjected to mild fire frying, obtains raw material after wine toast；
(3) raw material nano after wine toast is crushed, raw material after being crushed；
(4) herba taxilli and Cortex Eucommiae successively cleaned respectively, cleaned, dried；Distilled water is added to be decocted, filtered, be concentrated,
Gained concentrate is subjected to alcohol precipitation, respectively obtains herba taxilli sediment and Cortex Eucommiae sediment；Gained sediment is done by spraying
Dry, crushing, respectively obtains Viscum album extract and eucommia ulmoides extracts；
(5) raw material mixes with gained Viscum album extract and eucommia ulmoides extracts in step (4) after crushing gained in step (3)
It is even to get to it is described treatment caput femoris necrosis traditional Chinese powder medicine.
5. treating the preparation method of the traditional Chinese powder medicine of caput femoris necrosis according to claim 4, which is characterized in that step (1)
In, the wine of selection is the white wine that Alcohol degree is 52%Vol-63%Vol；
The mass ratio of the raw material and wine is 10:(1-2).
6. treating the preparation method of the traditional Chinese powder medicine of caput femoris necrosis according to claim 4, which is characterized in that step (3)
In, the smashed partial size of raw material is 20-100nm.
7. treating the preparation method of the traditional Chinese powder medicine of caput femoris necrosis according to claim 4, which is characterized in that step (4)
In, the additional amount of the distilled water is 4-6 times of each raw material traditional Chinese medicine quality, and the decocting time is 1.5-2h, when the alcohol precipitation
Between be 3-5h.
8. a kind of preparation method of the Chinese medicinal ointment of the treatment caput femoris necrosis, which comprises the following steps:
(1) each raw material cleaned, cleaned, crushed, be uniformly mixed, steamed after adding soaking in Chinese liquor, is then added
Distiller's yeast ferments, and obtains fermentation material；
(2) fermentation material is distilled, distillating extracting liquid is condensed into cream, obtain the Chinese medicine of the treatment caput femoris necrosis
Paste.
9. treating the preparation method of the Chinese medicinal ointment of caput femoris necrosis according to claim 8, which is characterized in that step (1)
In, it is 80-120 mesh that each raw material, which is crushed to partial size, and the temperature of the immersion is 25-28 DEG C, and the time of the immersion is 6-8
It, the Alcohol degree of the white wine is 50-65 degree.
10. treating the preparation method of the Chinese medicinal ointment of caput femoris necrosis according to claim 8, which is characterized in that step (1)
In, the temperature steamed is 120-200 DEG C, and the time steamed is 60-90 minutes, and the additive amount of the distiller's yeast is described
The 1-3wt% of raw material gross weight, the fermentation time are 30-60 days, and the temperature of the fermentation is 25-28 DEG C；
In step (2), by distillating extracting liquid mild fire infusion 1-2h after being boiled by fire.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101607022A (en) * | 2008-06-16 | 2009-12-23 | 潘峰勋 | A kind of Chinese medicine bone-knitting pellet preparation |
| CN102935120A (en) * | 2012-11-16 | 2013-02-20 | 赵宝祥 | Traditional Chinese medicine fumigating preparation for treating caput femoris necrosis, preparation method and fumigating method |
| CN109331127A (en) * | 2018-12-05 | 2019-02-15 | 李天基 | A kind of Chinese medicine composition and preparation method thereof for treating gout |
| CN109876053A (en) * | 2019-04-22 | 2019-06-14 | 长春健康未来医药科技有限公司 | A kind of acne-removing inflammation-diminishing, removing toxic substances of clearing liver prescription and its preparation method |
-
2019
- 2019-06-17 CN CN201910520596.0A patent/CN110141636A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101607022A (en) * | 2008-06-16 | 2009-12-23 | 潘峰勋 | A kind of Chinese medicine bone-knitting pellet preparation |
| CN102935120A (en) * | 2012-11-16 | 2013-02-20 | 赵宝祥 | Traditional Chinese medicine fumigating preparation for treating caput femoris necrosis, preparation method and fumigating method |
| CN109331127A (en) * | 2018-12-05 | 2019-02-15 | 李天基 | A kind of Chinese medicine composition and preparation method thereof for treating gout |
| CN109876053A (en) * | 2019-04-22 | 2019-06-14 | 长春健康未来医药科技有限公司 | A kind of acne-removing inflammation-diminishing, removing toxic substances of clearing liver prescription and its preparation method |
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