CN110279746A - A kind of massage cream and preparation method thereof for treating traumatic injury - Google Patents
A kind of massage cream and preparation method thereof for treating traumatic injury Download PDFInfo
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- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
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- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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- A61K2236/50—Methods involving additional extraction steps
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Abstract
The invention discloses a kind of massage creams and preparation method thereof for treating traumatic injury, according to parts by weight, including the following raw material: 2 ~ 10 parts of Europe blood circulation promoting pill, 1 ~ 5 part of sweet basil, 1 ~ 5 part of eupatorium.Massage cream is made according to traditional Chinese medical theory, using Europe blood circulation promoting pill, sweet basil, eupatorium as primary raw material in the present invention, and the symptoms such as muscles and bones hurt, blood stasis and swelling pain can be effectively relieved in cooperation massage effect.Experiments have shown that, massage cream of the invention is safe and effective by clinic application, aches to waist, neck, muscular strain, urarthritis, wrist, ankle are slightly sprained, intervertebral disc protrusion, protrusion, synovitis etc. all have preferable curative effect.
Description
Technical field
The invention belongs to technical field of pharmaceuticals, and in particular to a kind of massage cream and preparation method thereof for treating traumatic injury.
Background technique
Traumatic injury, muscles and bones hurt, blood stasis and swelling pain, derangement of Qi and blood, channels and collaterals are not mostly because of caused by external force in human body
Pass to overexert in the case that internal organs are impaired etc. or itself fault and caused by.Chinese medicine thinks its principle of reatment
Predominantly qi-regulating and blood, cold dispelling expelling pathogenic factors from muscles and skin, removes obstruction in channels to relieve pain, resuscitation with aromatics.
Treatment traumatic injury can use oral drug therapy at present, and this method can be relieved pain temporarily, but to the wound of kidney
Evil is very big, is particularly unsuitable for the sick and weak middle-aged and the old.Lotion, medicine oil can also usually be used by treating traumatic injury,
But existing medicine oil on the market is typically only capable to eliminate surface swelling and pain, but can not repair underlying soft tissue damage, and curative effect has centainly
Limitation.
Therefore, developing a kind of massage cream that can safely, effectively treat traumatic injury has preferable market prospects.
Summary of the invention
In consideration of it, the primary purpose of the present invention is that providing a kind of massage cream for treating traumatic injury, in the massage cream respectively
Component is synergistic, has preferable therapeutic effect to muscles and bones hurt, blood stasis and swelling pain etc., and safety is without side-effects.
Another object of the present invention is to provide a kind of preparation methods of massage cream for treating traumatic injury.
The present invention is achieved through the following technical solutions:
A kind of massage cream for treating traumatic injury, which is characterized in that according to parts by weight, including the following raw material: Europe blood circulation promoting pill 2 ~
10 parts, 1 ~ 5 part of sweet basil, 1 ~ 5 part of eupatorium.
Each raw material is reported state as follows in the present invention:
Europe blood circulation promoting pill: for the herb of Lamiaceae plant Europe blood circulation promoting pill GlechomahederaceaL..It is sweet in flavor；It is pungent；Cold nature.Entirely
Grass has the effect of heat-clearing, interpretation, diuresis, eliminating stasis to subdue swelling, and external application for curing traumatic injury, fracture, traumatic hemorrhage, boil carbuncle swells are red
The diseases such as poison, wind tinea.
Sweet basil: for the herb of Labiatae basil sweet basil Ocimum basilicum L..Acrid flavour, it is warm-natured.With hair
The effect of sweat inducing diaphoresis, expelling wind and removing dampness, removing blood stasis and acesodyne.For anemofrigid cold, headache, pipe abdomen fullness, indigestion, stomachache, enteritis
Diarrhea, treating swelling and pain by traumatic injury, rheumatic arthritis；Snake bite, eczema, dermatitis are controlled in external application.
Eupatorium: for the dry aerial parts of compositae plant eupatorium Eupatorium fortunei Turcz..Acrid flavour, property
It is flat.With aroma and dampness elimination, appetizing of being amusing, the effect of delivering relieving summer-heat.For turbi damp obstructing in middle-JIAO, gastral cavity ruffian evil of vomitting, sweet, halitosis in mouth,
Polysialia, summer-heat and damp table disease, alliteration are uncomfortable in chest.
The present invention is Empirical formula, and using Europe blood circulation promoting pill as monarch drug in a prescription, mildly bitter flavor is pungent, and slightly warm in nature is pungent, can be dissipated, and bitter energy softening hard masses dissipate
Knot, Wen Zeneng is logical, and gas perfume (or spice) can have one's ideas straightened out, function dispelling wind and removing obstruction in the meridians, removes long-pending analgesic, resuscitation with aromatics；Using sweet basil as ministerial drug, wind-dispelling detumescence,
Blood circulation, removing blood stasis and acesodyne help monarch drug in a prescription to achieve the effect that promoting blood circulation, dredging meridian and relieving pain；Assistant is had one's ideas straightened out and is mentioned with eupatorium, pungent-warm, warming meridian
Mind, wind-expelling pain-stopping, relaxing tendons and activating collaterals assist monarch-minister drug cold dispelling blood circulation.All medicines share plays cold dispelling expelling pathogenic factors from muscles and skin altogether, promoting blood circulation and removing obstruction in channels, dispels
Stasis of blood analgesic, the function of resuscitation with aromatics, according to clinical verification, to include waist, neck ache, muscular strain, urarthritis, wrist, foot
Wrist slightly sprains, intervertebral disc protrusion, protrusion, synovitis etc. all have preferable curative effect.
As a preferred embodiment, the massage cream further includes according to parts by weight 1 ~ 3 part of menthol.This
Suitable menthol is added in invention formula, the refrigerant sense of massage cream can be increased.
In another preferred embodiment, the massage cream further includes according to parts by weight that water-soluble capsicum is extracted
1-3 parts of object.Water solubility pepper extract of the present invention can be obtained by commercially available mode, can also voluntarily be prepared according to a conventional method
It obtains.Suitable water-soluble pepper extract is added in inventive formulation, can enhance analgesic effect with cold dispelling eliminating dampness.
In another preferred embodiment, the massage cream, according to parts by weight, further include Ginger P.E 1 ~
3 parts.Ginger P.E of the present invention can be obtained by commercially available mode, can also be voluntarily prepared according to a conventional method.This hair
Suitable Ginger P.E is added in bright formula, can promote blood, disperses cold-evil, reduces inflammation.
The present invention also provides a kind of preparation methods of massage cream for treating traumatic injury, include the following steps:
(1) pre-treatment: by Europe blood circulation promoting pill, sweet basil, eupatorium net system, silt impurity is removed, is dried in the shade；2 ~ 10 parts of Europe blood circulation promoting pill are taken, sieve
1 ~ 5 part is strangled, 1 ~ 5 part of eupatorium, is pulverized and sieved, mixes, obtains medicinal material coarse powder；
(2) extract: volatile oil, extracting solution filtering are collected in the water heating extracting that medicinal material coarse powder plus 8-15 times are measured 2-5 hours
Obtain filtrate；
(3) be concentrated: concentrating the filtrate to density is 1.0-1.5g/cm3, obtain medicinal substances extract；
(4) preparation of massage cream: taking medicinal substances extract and volatile oil, and paste substrate is added, be uniformly mixed to get.
Preferably, in step (4), the paste substrate is one in oleaginous base, emulsion bases or water-soluble base
Kind is several；Wherein, the oleaginous base is the mixing of one or both of vaseline or wool grease；The emulsion
Matrix is the mixing of one or both of octadecyl alcolol or lauryl sodium sulfate；The water-soluble base is polyethylene glycol.This
The dosage of invention paste substrate is the conventional amount used of this field.
The present invention collects volatile oil while effective component in extracting each raw material, and it is suitable that extract and volatile oil are added
Matrix be made massage cream, cooperate massage effect, surface swelling and pain can not only be eliminated, and underlying soft tissue damage can be repaired,
Preparation process simple possible.
Compared with prior art, the present invention having the following beneficial effects:
Massage cream, cooperation massage effect is made according to traditional Chinese medical theory, using Europe blood circulation promoting pill, sweet basil, eupatorium as primary raw material in the present invention
The symptoms such as muscles and bones hurt, blood stasis and swelling pain can be effectively relieved in fruit.Experiments have shown that, massage cream of the invention has safely by clinic application
Effect, aches to waist, neck, muscular strain, urarthritis, wrist, ankle are slightly sprained, intervertebral disc protrusion, protrusion, synovitis
Etc. all having preferable curative effect.
Specific embodiment
Further illustrate that the present invention, following embodiment are the specific embodiment party of the present invention below by specific embodiment
Formula, but embodiments of the present invention are not limited by following embodiments.
Embodiment 1:
A kind of massage cream for treating traumatic injury, according to parts by weight, including raw material: 5 parts of Europe blood circulation promoting pill, 2 parts of sweet basil, eupatorium 2
Part.
Preparation method are as follows:
(1) pre-treatment: by Europe blood circulation promoting pill, sweet basil, eupatorium net system, silt impurity is removed, is dried in the shade；5 parts of Europe blood circulation promoting pill are taken, sweet basil 2
Part, it 2 parts of eupatorium, pulverizes and sieves, mixes, obtain medicinal material coarse powder；
(2) it extracts: by medicinal material coarse powder plus 12 times of water heating extracting 4 hours measured, collecting volatile oil, extracting solution filters to get filtrate；
(3) be concentrated: concentrating the filtrate to density is 1.2g/cm3, obtain medicinal substances extract；
(4) preparation of massage cream: taking medicinal substances extract and volatile oil, and wool grease is added and absorbs mixing, adds Bai Fanshi
Woods be uniformly mixed, be uniformly mixed to get.
Embodiment 2:
A kind of massage cream for treating traumatic injury, according to parts by weight, including raw material: 6 parts of Europe blood circulation promoting pill, 3 parts of sweet basil, eupatorium 2
Part, 2 parts of menthol.
Preparation method are as follows:
(1) pre-treatment: by Europe blood circulation promoting pill, sweet basil, eupatorium net system, silt impurity is removed, is dried in the shade；6 parts of Europe blood circulation promoting pill are taken, sweet basil 3
Part, it 2 parts of eupatorium, pulverizes and sieves, mixes, obtain medicinal material coarse powder；
(2) it extracts: by medicinal material coarse powder plus 10 times of water heating extracting 3 hours measured, collecting volatile oil, extracting solution filtering
Obtain filtrate；
(3) be concentrated: concentrating the filtrate to density is 1.1g/cm3, obtain medicinal substances extract；
(4) preparation of massage cream: taking medicinal substances extract, menthol and volatile oil, and wool grease absorption is added and mixes, then plus
Enter albolene be uniformly mixed, be uniformly mixed to get.
Embodiment 3:
A kind of massage cream for treating traumatic injury, according to parts by weight, including raw material: 4 parts of Europe blood circulation promoting pill, 2 parts of sweet basil, eupatorium 2
Part, 1 part of Ginger P.E.
Preparation method are as follows:
(1) pre-treatment: by Europe blood circulation promoting pill, sweet basil, eupatorium net system, silt impurity is removed, is dried in the shade；4 parts of Europe blood circulation promoting pill are taken, sweet basil 2
Part, it 2 parts of eupatorium, pulverizes and sieves, mixes, obtain medicinal material coarse powder；
(2) it extracts: by medicinal material coarse powder plus 10 times of water heating extracting 4 hours measured, collecting volatile oil, extracting solution filters to get filtrate；
(3) be concentrated: concentrating the filtrate to density is 1.0g/cm3, obtain medicinal substances extract；
(4) preparation of massage cream: taking medicinal substances extract, Ginger P.E and volatile oil, and wool grease is added and absorbs mixing, then
Be added albolene be uniformly mixed, be uniformly mixed to get.
Embodiment 4:
A kind of massage cream for treating traumatic injury, according to parts by weight, including raw material: 5 parts of Europe blood circulation promoting pill, 2 parts of sweet basil, eupatorium 2
Part, 1 part of Ginger P.E, water-soluble 1 part of pepper extract.
Preparation method is the same as embodiment 1.
Embodiment 5:
A kind of massage cream for treating traumatic injury, according to parts by weight, including raw material: 5 parts of Europe blood circulation promoting pill, 3 parts of sweet basil, eupatorium 2
Part, water-soluble 1 part of pepper extract.
Preparation method is the same as embodiment 1.
Embodiment 6: clinical test
Test group: the massage cream prepared using embodiment 1.
Application method: taking given the test agent appropriate, and massage is smeared 3-5 minutes.
As a result: according to improvement, in vain, curing；As a result as shown in Table 1:
Table 1
| Number | Pain symptom improves | In vain | It cures | Number | ||
| 1 | It sprains one's back | 75 | 60 | 40 | Tid continuous 3 days | |
| 2 | Neck, soreness of waist pain | 65 | 58 | 48 | Tid continuous 3 days | |
| 3 | Muscular strain | 65 | 55 | 42 | Tid continuous 3 days | |
| 4 | Urarthritis | 7 | 4 | Tid continuous 1 week | ||
| 5 | Knee joint | 15 | 10 | Tid continuous 1 week | ||
| 6 | Wrist, ankle are slightly sprained | 50 | 35 | 30 | Tid continuous 3 days | |
| 7 | Sclerotin injury | 15 | 11 | Tid continuous 1 week | ||
| 8 | Intervertebral disc protrusion, protrusion | 12 | 9 | Tid continuous 1 week | ||
| 9 | Ligament injury | 17 | 13 | Tid continuous 1 week | ||
| 10 | Synovitis | 8 | 6 | Tid continuous 1 week |
By above-mentioned clinical effectiveness it is found that massage cream of the invention by each component synergy, can be effectively relieved muscles and bones hurt,
The symptoms such as blood stasis and swelling pain ache to waist, neck, muscular strain, urarthritis, wrist, ankle are slightly sprained, interverbebral disc is swollen
Out, protrusion, synovitis etc. all have preferable curative effect.
Claims (7)
1. a kind of massage cream for treating traumatic injury, which is characterized in that according to parts by weight, including the following raw material: Europe blood circulation promoting pill 2
~ 10 parts, 1 ~ 5 part of sweet basil, 1 ~ 5 part of eupatorium.
2. a kind of massage cream for treating traumatic injury according to claim 1, which is characterized in that according to parts by weight, also
Including 1 ~ 3 part of menthol.
3. a kind of massage cream for treating traumatic injury according to claim 1, which is characterized in that according to parts by weight, also
Including 1 ~ 3 part of water-soluble pepper extract.
4. a kind of massage cream for treating traumatic injury according to claim 1, which is characterized in that according to parts by weight, also
Including 1 ~ 3 part of Ginger P.E.
5. a kind of preparation method for the massage cream for treating traumatic injury, which comprises the steps of:
(1) pre-treatment: by Europe blood circulation promoting pill, sweet basil, eupatorium net system, silt impurity is removed, is dried in the shade；2 ~ 10 parts of Europe blood circulation promoting pill are taken, sieve
1 ~ 5 part is strangled, 1 ~ 5 part of eupatorium, is pulverized and sieved, mixes, obtains medicinal material coarse powder；
Extract: volatile oil is collected in the water heating extracting that medicinal material coarse powder plus 8-15 times are measured 2-5 hours, and extracting solution filters to get filtrate；
Concentration: concentrating the filtrate to density is 1.0-1.5g/cm3, obtain medicinal substances extract；
(4) preparation of massage cream: taking medicinal substances extract and volatile oil, and paste substrate is added, be uniformly mixed to get.
6. a kind of preparation method of massage cream for treating traumatic injury according to claim 5, which is characterized in that step
(4) in, the paste substrate is one or more of oleaginous base, emulsion bases or water-soluble base.
7. a kind of preparation method of massage cream for treating traumatic injury according to claim 6, which is characterized in that the oil
Lipid matrix is the mixing of one or both of vaseline or wool grease；The emulsion bases is octadecyl alcolol or dodecane
The mixing of one or both of base sodium sulphate；The water-soluble base is polyethylene glycol.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN111671715A (en) * | 2020-08-12 | 2020-09-18 | 揭阳市独角金枪草本植物股份有限公司 | Acne-removing composition and preparation method and application thereof |
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| 徐俊本编著: "《常见病中成药实用速查宝典》", 31 May 2014, 中国中医药出版社 * |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111671715A (en) * | 2020-08-12 | 2020-09-18 | 揭阳市独角金枪草本植物股份有限公司 | Acne-removing composition and preparation method and application thereof |
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