CN1170933C - 促胃动素同系物 - Google Patents

促胃动素同系物 Download PDF

Info

Publication number
CN1170933C
CN1170933C CNB988046822A CN98804682A CN1170933C CN 1170933 C CN1170933 C CN 1170933C CN B988046822 A CNB988046822 A CN B988046822A CN 98804682 A CN98804682 A CN 98804682A CN 1170933 C CN1170933 C CN 1170933C
Authority
CN
China
Prior art keywords
polypeptide
seq
residue
amino acid
forming
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB988046822A
Other languages
English (en)
Chinese (zh)
Other versions
CN1254375A (zh
Inventor
P・O・舍帕德
P·O·舍帕德
戴舍尔
T·A·戴舍尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/822,897 external-priority patent/US6380158B1/en
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of CN1254375A publication Critical patent/CN1254375A/zh
Application granted granted Critical
Publication of CN1170933C publication Critical patent/CN1170933C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CNB988046822A 1997-03-24 1998-03-23 促胃动素同系物 Expired - Fee Related CN1170933C (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US4110297P 1997-03-24 1997-03-24
US08/822,897 US6380158B1 (en) 1997-03-24 1997-03-24 Motilin homologs
US60/041,102 1997-03-24
US08/822,897 1997-03-24

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CNB2004100567973A Division CN100410375C (zh) 1997-03-24 1998-03-23 促胃动素同系物抗体

Publications (2)

Publication Number Publication Date
CN1254375A CN1254375A (zh) 2000-05-24
CN1170933C true CN1170933C (zh) 2004-10-13

Family

ID=26717805

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB988046822A Expired - Fee Related CN1170933C (zh) 1997-03-24 1998-03-23 促胃动素同系物

Country Status (9)

Country Link
JP (1) JP4335318B2 (no)
KR (1) KR20010005701A (no)
CN (1) CN1170933C (no)
AU (1) AU726423B2 (no)
BR (1) BR9808059A (no)
CA (1) CA2284733C (no)
NO (1) NO994614L (no)
NZ (1) NZ337958A (no)
WO (1) WO1998042840A1 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6627729B1 (en) 1997-03-24 2003-09-30 Zymogenetics, Inc. TML peptides
US6420521B1 (en) 1999-06-30 2002-07-16 Zymogenetics, Inc. Short gastrointestinal peptides
JP2003503055A (ja) * 1999-06-30 2003-01-28 ザイモジェネティクス，インコーポレイティド Ｓｇｉｐペプチド
EP1197496B8 (en) 1999-07-23 2007-10-03 Kenji Kangawa Novel peptides
ATE435871T1 (de) 1999-11-22 2009-07-15 Zymogenetics Inc Methode zur bildung einen peptid-rezeptor komplex mit zsig33 polypeptiden.
US6897286B2 (en) 2000-05-11 2005-05-24 Zymogenetics, Inc. Zsig33-like peptides
DE60142511D1 (de) * 2000-05-11 2010-08-19 Zymogenetics Inc Zsig33-ähnliche peptide
US6967237B2 (en) 2000-05-30 2005-11-22 Merck & Co., Inc. Ghrelin analogs
ES2338789T3 (es) 2003-06-18 2010-05-12 Tranzyme Pharma Inc. Antagonistas macrociclicos del receptor de motilina.
CN101528765B (zh) 2006-09-11 2015-04-22 欧塞拉治疗有限公司 用于治疗胃肠动力障碍病症的促胃动素受体的大环拮抗剂
CA2769013C (en) * 2009-07-29 2015-04-07 Daiichi Sankyo Company, Limited Motilin-like peptide compound having transmucosal absorbability imparted thereto
JP7049775B2 (ja) 2017-04-03 2022-04-07 リンナイ株式会社 表示装置

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8611832D0 (en) 1986-05-15 1986-06-25 Holland I B Polypeptide
US5006469A (en) * 1988-02-09 1991-04-09 Oregon Health Sciences University Vectors and host cells expressing prepromotilin and motilin-associated peptide (MAP)
US5037743A (en) 1988-08-05 1991-08-06 Zymogenetics, Inc. BAR1 secretion signal
JPH04299990A (ja) * 1991-03-27 1992-10-23 Sanwa Kagaku Kenkyusho Co Ltd モチリンアナログの精製方法

Also Published As

Publication number Publication date
CA2284733C (en) 2010-10-26
WO1998042840A1 (en) 1998-10-01
BR9808059A (pt) 2000-03-08
JP2001513651A (ja) 2001-09-04
KR20010005701A (ko) 2001-01-15
JP4335318B2 (ja) 2009-09-30
CN1254375A (zh) 2000-05-24
NO994614L (no) 1999-11-23
CA2284733A1 (en) 1998-10-01
NO994614D0 (no) 1999-09-23
AU726423B2 (en) 2000-11-09
AU6576998A (en) 1998-10-20
NZ337958A (en) 2001-03-30

Similar Documents

Publication Publication Date Title
CN1191273C (zh) 长效促胰岛肽
CN1051769C (zh) 甲状旁腺素类似物、它们的生产方法和含有它们的药物组合物
CN1150318C (zh) 用于预防或治疗恶性肿瘤的HER-2/neu蛋白胞内区
CN1675362A (zh) Hla－a24限制性癌抗原肽
CN1543476A (zh) 用于将蛋白定向到胞外体的方法和化合物
CN1902221A (zh) 基于中和表位的生长增强疫苗
CN1635898A (zh) 超级活性的猪生长激素释放激素类似物
CN1741814A (zh) 修饰的钠尿化合物、缀合物及其应用
CN1170933C (zh) 促胃动素同系物
CN1956997A (zh) 嵌合型可溶性超il－11和其应用
CN1258315A (zh) 哺乳动物细胞因子样因子7
CN1187203A (zh) 治疗由皮质甾类诱发的骨质减少的方法
CN1345246A (zh) 预防或治疗癌症及与癌症相关的骨损失的组合物和方法
CN1733918A (zh) 促胃动素同系物
CN1307485A (zh) 高钙血症治疗剂
CN1264980C (zh) 新型肿瘤抗原蛋白sart－3及其肿瘤抗原肽
CN1154727C (zh) 人甲状旁腺素的重组表达载体
CN1190437A (zh) 骨刺激因子
CN1553806A (zh) Sarp-1在治疗和/或预防硬皮病中的应用
CN1286973C (zh) 一种组蛋白甲基转移酶及其制备方法
CN1795205A (zh) Spex组合物和使用方法
CN1262562C (zh) 来源于sart－1的hla－a2限制性肿瘤抗原肽
CN1207387C (zh) 新型多肽及其编码基因
CN1359421A (zh) 新型多肽及其dna
CN1020923C (zh) 利用dna重组技术生产抑制素的方法

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
REG Reference to a national code

Ref country code: HK

Ref legal event code: GR

Ref document number: 1066507

Country of ref document: HK

CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20041013

Termination date: 20150323

EXPY Termination of patent right or utility model