CN116802211A - 针对白介素-22的抗体 - Google Patents

针对白介素-22的抗体 Download PDF

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Publication number
CN116802211A
CN116802211A CN202180092179.6A CN202180092179A CN116802211A CN 116802211 A CN116802211 A CN 116802211A CN 202180092179 A CN202180092179 A CN 202180092179A CN 116802211 A CN116802211 A CN 116802211A
Authority
CN
China
Prior art keywords
antibody
seq
cdr
antibodies
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202180092179.6A
Other languages
English (en)
Chinese (zh)
Inventor
J·M·D·拉斯特里克
J·P·希尔瓦
K·L·泰森
P·C·艾略特
S·F·R·雷森
Z·阿达史
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB Biopharma SRL
Original Assignee
UCB Biopharma SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCB Biopharma SRL filed Critical UCB Biopharma SRL
Publication of CN116802211A publication Critical patent/CN116802211A/zh
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55—Fab or Fab'
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN202180092179.6A 2020-12-07 2021-12-06 针对白介素-22的抗体 Pending CN116802211A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP20212127 2020-12-07
EP20212127.3 2020-12-07
PCT/EP2021/084400 WO2022122652A1 (en) 2020-12-07 2021-12-06 Antibodies against interleukin-22

Publications (1)

Publication Number Publication Date
CN116802211A true CN116802211A (zh) 2023-09-22

Family

ID=73740238

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202180092179.6A Pending CN116802211A (zh) 2020-12-07 2021-12-06 针对白介素-22的抗体

Country Status (13)

Country Link
US (1) US20230416357A1 (https=)
EP (1) EP4255925A1 (https=)
JP (1) JP7824957B2 (https=)
KR (1) KR20230118128A (https=)
CN (1) CN116802211A (https=)
AR (1) AR124250A1 (https=)
AU (1) AU2021398385A1 (https=)
BR (1) BR112023008265A2 (https=)
CA (1) CA3200836A1 (https=)
CO (1) CO2023007280A2 (https=)
IL (1) IL303294A (https=)
MX (1) MX2023006649A (https=)
WO (1) WO2022122652A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7532682B2 (ja) 2021-03-10 2024-08-13 バンジー， インコーポレイテッド マークアップフリーレッジグラブ

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Also Published As

Publication number Publication date
AR124250A1 (es) 2023-03-01
KR20230118128A (ko) 2023-08-10
AU2021398385A1 (en) 2023-07-13
JP7824957B2 (ja) 2026-03-05
US20230416357A1 (en) 2023-12-28
BR112023008265A2 (pt) 2024-02-06
CA3200836A1 (en) 2022-06-16
EP4255925A1 (en) 2023-10-11
WO2022122652A1 (en) 2022-06-16
JP2023551983A (ja) 2023-12-13
MX2023006649A (es) 2023-06-21
CO2023007280A2 (es) 2023-06-09
IL303294A (en) 2023-07-01

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