CN116059313A - 给药方案以及相关组合物和方法 - Google Patents

给药方案以及相关组合物和方法 Download PDF

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Publication number
CN116059313A
CN116059313A CN202211345357.4A CN202211345357A CN116059313A CN 116059313 A CN116059313 A CN 116059313A CN 202211345357 A CN202211345357 A CN 202211345357A CN 116059313 A CN116059313 A CN 116059313A
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CN
China
Prior art keywords
certain embodiments
compstatin
compstatin analog
moiety
amino acid
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Pending
Application number
CN202211345357.4A
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English (en)
Chinese (zh)
Inventor
F·格罗西
P·德沙特莱
C·弗朗索瓦
P·约翰逊
C·维加
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Apellis Pharmaceuticals Inc
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Apellis Pharmaceuticals Inc
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Publication of CN116059313A publication Critical patent/CN116059313A/zh
Pending legal-status Critical Current

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    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K7/64—Cyclic peptides containing only normal peptide links
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    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

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  • Bioinformatics & Cheminformatics (AREA)
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  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Epidemiology (AREA)
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  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Heart & Thoracic Surgery (AREA)
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CN202211345357.4A 2017-04-07 2018-04-09 给药方案以及相关组合物和方法 Pending CN116059313A (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201762483295P 2017-04-07 2017-04-07
US62/483,295 2017-04-07
US201762485343P 2017-04-13 2017-04-13
US62/485,343 2017-04-13
PCT/US2018/026753 WO2018187813A1 (en) 2017-04-07 2018-04-09 Dosing regimens and related compositions and methods
CN201880037570.4A CN110831544B (zh) 2017-04-07 2018-04-09 长效坎普他汀类似物、其组合物的给药方案及其医药用途

Related Parent Applications (1)

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CN201880037570.4A Division CN110831544B (zh) 2017-04-07 2018-04-09 长效坎普他汀类似物、其组合物的给药方案及其医药用途

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CN116059313A true CN116059313A (zh) 2023-05-05

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CN202211345357.4A Pending CN116059313A (zh) 2017-04-07 2018-04-09 给药方案以及相关组合物和方法
CN201880037570.4A Active CN110831544B (zh) 2017-04-07 2018-04-09 长效坎普他汀类似物、其组合物的给药方案及其医药用途

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US (3) US11040107B2 (enExample)
EP (2) EP3606465A4 (enExample)
JP (3) JP2020516607A (enExample)
KR (2) KR20190139931A (enExample)
CN (2) CN116059313A (enExample)
AU (2) AU2018249627B2 (enExample)
BR (1) BR112019020955A2 (enExample)
CA (1) CA3059304A1 (enExample)
IL (3) IL269844B2 (enExample)
MX (2) MX2019012033A (enExample)
WO (1) WO2018187813A1 (enExample)

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JP6522337B2 (ja) 2011-05-11 2019-05-29 アペリス・ファーマシューティカルズ・インコーポレイテッドＡｐｅｌｌｉｓ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ，Ｉｎｃ． 細胞反応性、長時間作用型または標的化コンプスタチン類似体およびその使用
PT2920201T (pt) * 2012-11-15 2020-04-03 Apellis Pharmaceuticals Inc Análogos de compstatina de longa ação e composições e métodos relacionados
WO2014152391A1 (en) 2013-03-15 2014-09-25 Apellis Pharmaceuticals, Inc. Cell-penetrating compstatin analogs and uses thereof
MX392574B (es) 2015-10-07 2025-03-24 Apellis Pharmaceuticals Inc Análogos de compstatina de acción prolongada para usarse en el tratamiento de trastornos oculares
KR20190139931A (ko) 2017-04-07 2019-12-18 아펠리스 파마슈티컬스 인코포레이티드 투여 요법 및 관련 조성물 및 방법
MA51162A (fr) 2017-12-15 2020-10-21 Apellis Pharmaceuticals Inc Schémas posologiques et compositions et procédés associés
EA202092684A1 (ru) 2018-08-27 2021-03-11 Ридженерон Фармасьютикалз, Инк. Применение рамановской спектроскопии для последующей очистки
CN115243673A (zh) * 2020-01-07 2022-10-25 阿佩利斯制药有限公司 阵发性睡眠性血红蛋白尿症的治疗
US20250000936A1 (en) * 2021-09-09 2025-01-02 Apellis Pharmaceuticals, Inc. Treatment of geographic atrophy
CN116459342A (zh) * 2023-03-27 2023-07-21 中国人民解放军总医院海南医院 一种用于急性心肌梗死闭塞血管远端的溶栓组合物

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