AU4648197A - Peptides and peptidomimetics for inhibiting complement activation - Google Patents
Peptides and peptidomimetics for inhibiting complement activationInfo
- Publication number
- AU4648197A AU4648197A AU46481/97A AU4648197A AU4648197A AU 4648197 A AU4648197 A AU 4648197A AU 46481/97 A AU46481/97 A AU 46481/97A AU 4648197 A AU4648197 A AU 4648197A AU 4648197 A AU4648197 A AU 4648197A
- Authority
- AU
- Australia
- Prior art keywords
- peptidomimetics
- peptides
- complement activation
- inhibiting complement
- inhibiting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/472—Complement proteins, e.g. anaphylatoxin, C3a, C5a
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1997/016850 WO1999013899A1 (en) | 1997-09-17 | 1997-09-17 | Peptides and peptidomimetics for inhibiting complement activation |
Publications (1)
Publication Number | Publication Date |
---|---|
AU4648197A true AU4648197A (en) | 1999-04-05 |
Family
ID=22261695
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU46481/97A Abandoned AU4648197A (en) | 1997-09-17 | 1997-09-17 | Peptides and peptidomimetics for inhibiting complement activation |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU4648197A (en) |
WO (1) | WO1999013899A1 (en) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2833202C (en) * | 2002-09-20 | 2017-08-01 | The Trustees Of The University Of Pennsylvania | Compstatin analogs with improved activity |
CA2579635A1 (en) | 2003-09-10 | 2005-03-17 | Baxter International Inc. | Peptides that inhibit complement activation |
WO2005118020A1 (en) * | 2004-04-21 | 2005-12-15 | Allvivo, Inc. | Surface coating comprising bioactive compound |
EP1739078A1 (en) | 2005-05-30 | 2007-01-03 | Jerini AG | Antagonists of C5a-receptor |
US8168584B2 (en) | 2005-10-08 | 2012-05-01 | Potentia Pharmaceuticals, Inc. | Methods of treating age-related macular degeneration by compstatin and analogs thereof |
RU2474586C2 (en) | 2005-11-28 | 2013-02-10 | Дзе Трастиз Оф Дзе Юниверсити Оф Пенсильвания | Efficient compstatin analogues |
US8442776B2 (en) | 2007-06-08 | 2013-05-14 | The Trustees Of The University Of Pennsylvania | Structure of compstatin-C3 complex and use for rational drug design |
WO2009005651A2 (en) | 2007-06-29 | 2009-01-08 | The Trustees Of The University Of Pennsylvania | Complement-mediated thrombophilic assay |
WO2009014633A1 (en) * | 2007-07-20 | 2009-01-29 | Trustees Of The University Of Pennsylvania | Method of treating acute respiratory distress syndrome |
AU2009215846B2 (en) | 2008-02-19 | 2014-08-14 | The Trustees Of The University Of Pennsylvania | Complement inhibitors as therapeutic agents for treatment of cancer |
EP2331113A4 (en) | 2008-08-20 | 2012-03-14 | Univ Pennsylvania | Complement inhibitors for treatment of injury form intracerebral hemorrhage |
CA2738930C (en) | 2008-09-30 | 2021-08-17 | The Trustees Of The University Of Pennsylvania | Method of inhibiting biomaterial-induced procoagulant activity using complement inhibitors |
WO2010127336A1 (en) * | 2009-05-01 | 2010-11-04 | The Trustees Of The University Of Pennsylvania | Modified compstatin with peptide backbone and c-terminal modifications |
WO2011106635A1 (en) | 2010-02-25 | 2011-09-01 | The Trustees Of The University Of Pennsylvania | Treatment of sepsis using complement inhibitors |
US9421240B2 (en) | 2010-06-22 | 2016-08-23 | Apellis Pharmaceuticals, Inc. | Compstatin analogs for treatment of neuropathic pain |
US20140113874A1 (en) | 2010-09-23 | 2014-04-24 | The Trustees Of The University Of Pennsylvania | Modified Compstatin With Improved Stability And Binding Properties |
WO2012135624A1 (en) | 2011-04-01 | 2012-10-04 | The Trustees Of The University Of Pennsylvania | Treatment of colon cancer using complement inhibitors |
WO2012162215A1 (en) | 2011-05-20 | 2012-11-29 | The Trustees Of The University Of Pennsylvania | Promotion of fracture healing using complement inhibitors |
WO2012174055A1 (en) | 2011-06-13 | 2012-12-20 | The Trustees Of The University Of Pennsylvania | Wound healing using complement inhibitors |
JP6249949B2 (en) | 2011-09-07 | 2017-12-20 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | Compstatin analogs with improved pharmacokinetic properties |
SI3660033T1 (en) | 2012-11-15 | 2021-09-30 | Apellis Pharmaceuticals, Inc. | Long-acting compstatin analogs and related compositions and methods |
WO2014152391A1 (en) | 2013-03-15 | 2014-09-25 | Apellis Pharmaceuticals, Inc. | Cell-penetrating compstatin analogs and uses thereof |
WO2015103438A2 (en) | 2014-01-02 | 2015-07-09 | Genelux Corporation | Oncolytic virus adjunct therapy with agents that increase virus infectivity |
JP6968787B2 (en) | 2015-10-07 | 2021-11-17 | アペリス・ファーマシューティカルズ・インコーポレイテッドApellis Pharmaceuticals, Inc. | Dosing regimen |
KR20190139931A (en) | 2017-04-07 | 2019-12-18 | 아펠리스 파마슈티컬스 인코포레이티드 | Dosage regimens and related compositions and methods |
RU2020128624A (en) * | 2018-02-27 | 2022-03-28 | Зп Спв 3 К/С | COMPSTATIN ANALOGUES AND THEIR MEDICAL APPLICATIONS |
MX2020010520A (en) | 2018-04-06 | 2021-01-15 | Univ Pennsylvania | Compstatin analogs with increased solubility and improved pharmacokinetic properties. |
EP4021921A1 (en) | 2019-08-27 | 2022-07-06 | Zp Spv 3 K/S | Compstatin analogues and their medical uses |
MX2023000679A (en) | 2020-07-16 | 2023-04-18 | Zp Spv 3 K/S | Inhibitors of complement factor c3 and their medical uses. |
-
1997
- 1997-09-17 AU AU46481/97A patent/AU4648197A/en not_active Abandoned
- 1997-09-17 WO PCT/US1997/016850 patent/WO1999013899A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO1999013899A1 (en) | 1999-03-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |