CN115697976A - 一种氯代化合物的制备方法 - Google Patents
一种氯代化合物的制备方法 Download PDFInfo
- Publication number
- CN115697976A CN115697976A CN202180041874.XA CN202180041874A CN115697976A CN 115697976 A CN115697976 A CN 115697976A CN 202180041874 A CN202180041874 A CN 202180041874A CN 115697976 A CN115697976 A CN 115697976A
- Authority
- CN
- China
- Prior art keywords
- solvent
- reagent
- compound
- etoac
- mixed solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
公开了一种氯代化合物的制备方法，具体公开了式(I)化合物的制备方法。
Description
PCT国内申请，说明书已公开。
Claims (13)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2020105287785 | 2020-06-11 | ||
| CN202010528778 | 2020-06-11 | ||
| PCT/CN2021/099336 WO2021249468A1 (zh) | 2020-06-11 | 2021-06-10 | 一种氯代化合物的制备方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN115697976A true CN115697976A (zh) | 2023-02-03 |
Family
ID=78845384
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202180041874.XA Pending CN115697976A (zh) | 2020-06-11 | 2021-06-10 | 一种氯代化合物的制备方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20230219902A1 (zh) |
| EP (1) | EP4166543A1 (zh) |
| JP (1) | JP2023528976A (zh) |
| KR (1) | KR20230023750A (zh) |
| CN (1) | CN115697976A (zh) |
| WO (1) | WO2021249468A1 (zh) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105263913B (zh) * | 2013-06-14 | 2017-12-15 | 广东东阳光药业有限公司 | 硫代1,2,4‑三唑衍生物及其制备方法 |
| CN103524440B (zh) * | 2013-10-15 | 2015-09-09 | 苏州鹏旭医药科技有限公司 | 痛风治疗药Lesinurad的制备方法及Lesinurad中间体 |
| CN104529848A (zh) * | 2014-11-10 | 2015-04-22 | 安徽万邦医药科技有限公司 | 一种1-环丙基-4-异硫氰酰基萘的合成方法 |
| DK3473617T3 (da) * | 2016-06-17 | 2022-11-28 | Medshine Discovery Inc | Halogeneret forbindelse og aksiale, chirale isomerer deraf |
-
2021
- 2021-06-10 WO PCT/CN2021/099336 patent/WO2021249468A1/zh unknown
- 2021-06-10 KR KR1020237001128A patent/KR20230023750A/ko active Search and Examination
- 2021-06-10 CN CN202180041874.XA patent/CN115697976A/zh active Pending
- 2021-06-10 US US18/000,939 patent/US20230219902A1/en active Pending
- 2021-06-10 JP JP2022576055A patent/JP2023528976A/ja active Pending
- 2021-06-10 EP EP21823032.4A patent/EP4166543A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021249468A1 (zh) | 2021-12-16 |
| JP2023528976A (ja) | 2023-07-06 |
| EP4166543A1 (en) | 2023-04-19 |
| US20230219902A1 (en) | 2023-07-13 |
| KR20230023750A (ko) | 2023-02-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination |