CN115554196A

CN115554196A - Ganoderma mouth wash and preparation method thereof

Info

Publication number: CN115554196A
Application number: CN202211408214.3A
Authority: CN
Inventors: 毛景华; 张泰顺; 黄敏
Original assignee: Wuyishan Yuanshengtai Biotechnology Co ltd
Current assignee: Wuyishan Yuanshengtai Biotechnology Co ltd
Priority date: 2022-11-10
Filing date: 2022-11-10
Publication date: 2023-01-03

Abstract

The invention discloses a lucid ganoderma gargle and a preparation method thereof, wherein the lucid ganoderma gargle comprises 1-2% of lucid ganoderma extract, 3-4.5% of plant extract, 0.1-0.5% of bacteriostatic agent, 1-2% of wetting agent, 0.02-0.04% of preservative, 0.05-0.09% of taste conditioning agent, 0.05-0.1% of sweetening agent and the balance of deionized water. The invention provides a lucid ganoderma gargle and a preparation method thereof, wherein the gargle is prepared by adopting lucid ganoderma extracts and plant extracts as main components, has good mouth feel, can clean oral cavity and teeth, relieves uncomfortable symptoms such as dental ulcer, gingival bleeding, gingivitis, periodontitis, sore throat and the like, has good sterilization effect, protects the health of the oral cavity, keeps fresh breath, is accompanied with light plant fragrance, and has safe components, no toxic or side effect and no potential safety hazard when being eaten by mistake.

Description

Ganoderma mouth wash and preparation method thereof

Technical Field

The invention relates to the technical field of ganoderma lucidum processing, and particularly relates to ganoderma lucidum mouthwash and a preparation method thereof.

Background

The conventional tooth brushing can only remove 40 to 50 percent of dental plaque and 30 percent of adjacent dental plaque, and has no effect on removing the dental plaque at the gingival margin, between the teeth and on the surface of the soft tissue of the oral cavity. The gargle can be deep in various parts of the oral cavity of a person, including the gingival edge and the slits between teeth which are difficult to contact with the toothbrush, and is a good measure for assisting in controlling dental plaque. The mouthwash becomes an indispensable oral cleaning product in modern life, has the advantage of convenient use compared with toothpaste, and is the best choice for guaranteeing oral hygiene for old people with teeth falling off and patients with odontopathy who cannot tolerate tooth brushing. In recent years, with the increasing health consciousness of people, the requirement for mouthwash is increasing, and the auxiliary prevention of oral diseases besides tooth cleaning is also needed.

The main medicinal components and effects of the currently marketed mouthwash products are fluoride gargle, triclosan, thangianpan, hexadecahui chlorine, and mouthwash containing chemical drugs such as chlorhexidine gluconate, nitric acid steel, and Chisi oxide. Although these mouthwashes have strong antibacterial and bacteriostatic effects, and can effectively remove dental plaque and prevent dental caries, these chemicals often cause strong irritation and damage to the components of the dental mucosa, causing bacteria to attack teeth more easily. Chemical agent residue and excessive use can cause technical defects of human body damage and the like. How to overcome present su saliva irritability strong, can damage tooth mucosa composition, cause the bacterium to change and invade the tooth, and avoid chemical agent to remain too much to cause the harm to the human body for the difficult problem that the achievement is waited to solve urgently.

Disclosure of Invention

The invention aims to provide a ganoderma lucidum mouthwash and a preparation method thereof to solve the problems.

In order to achieve the purpose, the invention adopts the following technical scheme:

a gargle of glossy ganoderma comprises 1-2% of glossy ganoderma extract, 3-4.5% of plant extract, 0.1-0.5% of bacteriostatic agent, 1-2% of wetting agent, 0.02-0.04% of preservative, 0.05-0.09% of taste conditioning agent, 0.05-0.1% of sweetening agent and the balance of deionized water.

Preferably, the plant extract includes coptis chinensis extract, scutellaria baicalensis extract, vanilla extract, honeysuckle extract, isatis root extract, forsythia suspensa extract, licorice extract, thyme extract and clove extract.

Preferably, the bacteriostatic agent comprises ethyl palmitate and ethanol, and the mass fraction ratio of the bacteriostatic agent is (0.5-1): (0.5-1).

Preferably, the taste regulator comprises methyl salicylate, menthyl, mannitol and stevioside, and the mass fraction ratio of the taste regulator is (1-2): (1-3): (1-2): (2-3).

Preferably, the humectant is at least one of sodium hyaluronate or glycerin, the sweetener is at least one of sorbitol, xylitol or maltitol, and the preservative is at least one of ethylparaben, potassium sorbate or sodium benzoate.

A preparation method of a ganoderma mouth wash comprises the following steps:

s1, drying, sieving, extracting, desolventizing and filtering the plant to obtain a plant extract;

s2, drying, sieving, dissolving and extracting the lucid ganoderma to obtain a lucid ganoderma extract;

s3, weighing 1-2% of lucid ganoderma extract, 3-4.5% of plant extract, 0.1-0.5% of bacteriostatic agent, 1-2% of wetting agent, 0.02-0.04% of preservative, 0.05-0.09% of taste conditioning agent, 0.05-0.1% of sweetening agent and the balance of water according to the proportion;

s4, respectively and sequentially introducing the groups into a container, and ultrasonically stirring to obtain a mixed solution;

and S5, defoaming the mixed solution under negative pressure to finally obtain the ganoderma lucidum mouthwash.

Preferably, step S1 is specifically:

s11, respectively placing the plants in a drying box for drying at the drying temperature of 50-60 ℃ until the moisture content is less than 5%;

s12, crushing the dried plants, and then sieving the crushed plants with a 100-mesh sieve to obtain fine powder of the plants;

s13, sequentially adding dried plant fine powder into a crushed subcritical extraction kettle, adding butane serving as an extraction solvent until the plant fine powder is immersed, controlling the extraction temperature in the kettle to be 30-35 ℃, the extraction pressure to be 0.7-0.9 MPa, and the extraction time to be 1h, and repeatedly extracting for three times;

s14, decompressing the crushed subcritical extraction kettle until the pressure in the kettle is reduced to-0.05 MPa, desolventizing the mixture extracted in the S13 by a compressor, and collecting vegetable oil;

s15, carrying out suction filtration on the vegetable oil prepared in the S14 to obtain a plant extract.

Preferably, step S2 is specifically:

s21, placing the lucid ganoderma in a drying box for drying at the temperature of 40-50 ℃ until the water content is less than 5%;

s22, crushing the dried lucid ganoderma, and then sieving the smashed lucid ganoderma by a 200-mesh sieve to obtain lucid ganoderma fine powder;

s23, placing the ganoderma lucidum fine powder into an extraction device, adding 95% ethanol with the mass 8 times that of the ganoderma lucidum fine powder, dissolving, adding 10% dipotassium phosphate aqueous solution with the mass 20 times that of the ganoderma lucidum fine powder, shaking for extraction for 10min, and standing for 2h to obtain the ganoderma lucidum extract.

Preferably, the ultrasonic stirring frequency in step S4 is 20-40 KHz, and the stirring time is 40-50 min.

Preferably, the ultrasonic agitation in step S4 is specifically performed in a closed environment, and the agitation pressure is 6 to 10MPa.

After the technical scheme is adopted, compared with the background technology, the invention has the following beneficial effects:

1. the invention provides a lucid ganoderma gargle and a preparation method thereof, wherein the gargle is prepared by adopting lucid ganoderma extracts and plant extracts as main components, has good mouth feel, can clean oral cavity and teeth, relieves uncomfortable symptoms such as oral ulcer, gingival bleeding, gingivitis, periodontitis, sore throat and the like, has good sterilization effect, protects the health of the oral cavity, keeps fresh breath, is accompanied by light plant faint scent, has safe components, has no toxic or side effect, and has no potential safety hazard when being eaten by mistake.

2. The invention provides a ganoderma mouth wash and a preparation method thereof, wherein ganoderma spore powder is rich in ganoderma polysaccharide and ganoderma triterpene components, wherein the ganoderma polysaccharide is beneficial to improving the blood circulation of gingival capillaries, promoting metabolism, activating oral mucosa tissues, promoting metabolism, accelerating the healing of ulcer surfaces and helping the maintenance and repair of the gingival tissues; the Ganoderma triterpene can inhibit streptococcus mutans from producing dextran, can prevent dental plaque and dental caries, and can relieve gingival swelling and pain and discomfort caused by periodontal disease.

Drawings

FIG. 1 is a block flow diagram of the present invention.

Detailed Description

In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention is further described in detail with reference to the following embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.

Example 1

Referring to fig. 1, the present invention discloses a ganoderma mouth wash, which comprises 1% of ganoderma extract, 3.5% of plant extract, 0.2% of bacteriostatic agent, 1% of wetting agent, 0.03% of preservative, 0.06% of taste modifier, 0.05% of sweetener, and the balance deionized water.

The plant extracts include Coptidis rhizoma extract, scutellariae radix extract, herba Caryopteridis Incanae extract, flos Lonicerae extract, radix Isatidis extract, fructus forsythiae extract, glycyrrhrizae radix extract, herba Thymi extract and flos Caryophylli extract.

The bacteriostatic agent comprises ethyl palmitate and ethanol, and the mass fraction ratio of the bacteriostatic agent is 0.5.

The taste conditioning agent comprises methyl salicylate, menthyl, mannitol and stevioside, and the mass fraction ratio is 2.

The humectant is at least one of sodium hyaluronate or glycerol, the sweetener is at least one of sorbitol, xylitol or maltitol, and the preservative is at least one of ethylparaben, potassium sorbate or sodium benzoate.

The invention also discloses a preparation method of the ganoderma mouth wash, which comprises the following steps:

s1, drying, sieving, extracting, desolventizing and filtering the plants to obtain plant extracts;

s3, weighing 1% of lucid ganoderma extract, 3.5% of plant extract, 0.2% of bacteriostatic agent, 1% of wetting agent, 0.03% of preservative, 0.06% of taste regulator, 0.05% of sweetening agent and the balance of deionized water according to the mixture ratio;

and S5, defoaming the mixed solution under negative pressure to finally obtain the ganoderma mouth wash.

The step S1 specifically comprises the following steps:

s11, respectively placing the plants in a drying box for drying at the drying temperature of 55 ℃ until the moisture content is less than 5%;

s13, sequentially adding dried plant fine powder into a crushing subcritical extraction kettle, adding butane serving as an extraction solvent until the plant fine powder is immersed, controlling the extraction temperature in the kettle to be 30 ℃, the extraction pressure to be 0.7MPa, and the extraction time to be 1 hour, and repeatedly extracting for three times;

s14, decompressing the crushed subcritical extraction kettle until the pressure in the kettle is reduced to-0.05 MPa, desolventizing the mixture extracted in the step S13 by using a compressor, and collecting vegetable oil;

The step S2 specifically comprises the following steps:

s21, placing the lucid ganoderma in a drying box for drying at the drying temperature of 40 ℃ until the moisture content is less than 5%;

s23, placing the ganoderma lucidum fine powder into an extraction device, adding 95% ethanol with the mass 8 times that of the ganoderma lucidum fine powder, dissolving, adding 10% dipotassium hydrogen phosphate aqueous solution with the mass 20 times that of the ganoderma lucidum fine powder, shaking for extraction for 10min, and standing for 2h to obtain the ganoderma lucidum extract.

In the step S4, the ultrasonic stirring frequency is 40KHz, and the stirring time is 40min.

In step S4, the ultrasonic stirring is carried out in a closed environment, and the stirring pressure is 8MPa.

Example 2

Referring to fig. 1, the present invention discloses a ganoderma mouth wash, which comprises 2% of ganoderma extract, 3% of plant extract, 0.1% of bacteriostatic agent, 1% of wetting agent, 0.04% of preservative, 0.06% of taste modifier, 0.06% of sweetener, and the balance deionized water.

The bacteriostatic agent comprises ethyl palmitate and ethanol, and the mass fraction ratio of the bacteriostatic agent is 0.5:0.6.

the taste conditioning agent comprises methyl salicylate, menthyl, mannitol and stevioside, and the mass fraction ratio of the taste conditioning agent is 1.

s3, weighing the components according to the mixture ratio, wherein the lucid ganoderma extract accounts for 2 percent, the plant extract accounts for 3 percent, the bacteriostatic agent accounts for 0.1 percent, the wetting agent accounts for 1 percent, the preservative accounts for 0.04 percent, the taste conditioning agent accounts for 0.06 percent, the sweetening agent accounts for 0.06 percent, and the balance is deionized water;

The step S1 specifically comprises the following steps:

s11, respectively placing the plants in a drying box for drying at the drying temperature of 50 ℃ until the moisture content is less than 5%;

s13, sequentially adding the dried plant fine powder into a crushing subcritical extraction kettle, adding butane serving as an extraction solvent until the plant fine powder is immersed, controlling the extraction temperature in the kettle to be 30 ℃, the extraction pressure to be 0.7MPa, and the extraction time to be 1h, and repeatedly extracting for three times;

The step S2 specifically comprises the following steps:

s21, placing the lucid ganoderma in a drying box for drying at 40 ℃ until the moisture content is less than 5%;

In the step S4, the ultrasonic stirring frequency is 30KHz, and the stirring time is 40min.

In the step S4, the ultrasonic stirring is specifically carried out in a closed environment, and the stirring pressure is 8MPa.

Example 3

Referring to fig. 1, the present invention discloses a ganoderma lucidum mouth wash, which comprises 2% of ganoderma lucidum extract, 4% of plant extract, 0.13% of bacteriostatic agent, 2% of wetting agent, 0.02% of preservative, 0.05% of taste modifier, 0.08% of sweetener, and the balance deionized water.

The bacteriostatic agent comprises ethyl palmitate and ethanol, and the mass fraction ratio of the bacteriostatic agent is 0.6.

s3, weighing the components according to the mixture ratio, wherein the components comprise 2% of lucid ganoderma extract, 4% of plant extract, 0.13% of bacteriostatic agent, 2% of wetting agent, 0.02% of preservative, 0.05% of taste conditioning agent, 0.08% of sweetening agent and the balance of deionized water;

The step S1 specifically comprises the following steps:

s13, sequentially adding the dried plant fine powder into a crushing subcritical extraction kettle, adding butane serving as an extraction solvent until the plant fine powder is immersed, controlling the extraction temperature in the kettle to be 35 ℃, the extraction pressure to be 0.7MPa, and the extraction time to be 1h, and repeatedly extracting for three times;

The step S2 specifically comprises the following steps:

s22, crushing the dried lucid ganoderma, and then sieving the smashed lucid ganoderma through a 200-mesh sieve to obtain lucid ganoderma fine powder;

In the step S4, the ultrasonic stirring is specifically carried out in a closed environment, and the stirring pressure is 7MPa.

The above description is only for the preferred embodiment of the present invention, but the scope of the present invention is not limited thereto, and any changes or substitutions that can be easily conceived by those skilled in the art within the technical scope of the present invention are included in the scope of the present invention. Therefore, the protection scope of the present invention shall be subject to the protection scope of the claims.

Claims

1. A ganoderma lucidum gargle is characterized in that: comprises 1-2% of ganoderma lucidum extract, 3-4.5% of plant extract, 0.1-0.5% of bacteriostatic agent, 1-2% of wetting agent, 0.02-0.04% of preservative, 0.05-0.09% of taste conditioning agent, 0.05-0.1% of sweetening agent and the balance of deionized water.

2. The ganoderma lucidum mouthwash according to claim 1, wherein: the plant extract comprises Coptidis rhizoma extract, scutellariae radix extract, herba Caryopteridis Incanae extract, flos Lonicerae extract, radix Isatidis extract, fructus forsythiae extract, glycyrrhrizae radix extract, herba Thymi extract and flos Caryophylli extract.

3. The ganoderma lucidum mouthwash according to claim 1, wherein: the bacteriostatic agent comprises ethyl palmitate and ethanol, and the mass fraction ratio of the bacteriostatic agent is (0.5-1): (0.5-1).

4. The ganoderma lucidum mouthwash according to claim 1, wherein: the taste conditioning agent comprises methyl salicylate, menthyl, mannitol and stevioside, and the mass fraction ratio of the taste conditioning agent is (1-2): (1-3): (1-2): (2-3).

5. The ganoderma lucidum mouthwash of claim 1, wherein: the humectant is at least one of sodium hyaluronate or glycerol, the sweetener is at least one of sorbitol, xylitol or maltitol, and the preservative is at least one of ethylparaben, potassium sorbate or sodium benzoate.

6. The method for preparing a gargle containing Ganoderma lucidum according to any of claims 1 to 5, comprising the steps of:

s4, drying, sieving, extracting, desolventizing and filtering the plants to obtain plant extracts;

7. The method for preparing the ganoderma lucidum mouthwash of claim 6, wherein the step S1 is specifically as follows:

8. The method for preparing the ganoderma lucidum mouthwash of claim 6, wherein the step S2 specifically comprises the following steps:

s21, placing the lucid ganoderma in a drying box for drying at the drying temperature of 40-50 ℃ until the water content is less than 5%;

9. The method for preparing a gargle containing ganoderma lucidum as claimed in claim 6, wherein the method comprises the following steps: in the step S4, the frequency of ultrasonic stirring is 20-40 KHz, and the stirring time is 40-50 min.

10. The method for preparing a gargle of ganoderma lucidum as claimed in claim 9, wherein the method comprises the following steps: in the step S4, the ultrasonic stirring is specifically carried out in a closed environment, and the stirring pressure is 6-10 MPa.