CN108938524A - A kind of dendrobium candidum toothpaste and preparation method thereof - Google Patents
A kind of dendrobium candidum toothpaste and preparation method thereof Download PDFInfo
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- CN108938524A CN108938524A CN201811126879.9A CN201811126879A CN108938524A CN 108938524 A CN108938524 A CN 108938524A CN 201811126879 A CN201811126879 A CN 201811126879A CN 108938524 A CN108938524 A CN 108938524A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
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Abstract
The invention discloses a kind of dendrobium candidum toothpaste, in parts by weight include following components: 5~15 parts of dendrobium candidum extract, 40~50 parts of moisturizer, 15~20 parts of rubbing agent, 0.1~0.3 part of preservative, 0.5~1.0 part of binder, 2.0~3.0 parts of foaming agent, 0.2~0.5 part of sweetener, 10~15 parts of Dental Erosion nursing compositions, 10~25 parts of deionized water.The effect of cost of material of the present invention is low, is formulated simple science, gives full play to dendrobium candidum effective component, has preferable application value.
Description
Technical field
The present invention relates to daily necessities fields, and in particular to a kind of dendrobium candidum toothpaste and preparation method thereof.
Background technique
Toothpaste is indispensable oral cleaning amenities in people's daily life, with the increasing of people's health care consciousness
By force, requirement of the consumer to toothpaste is higher and higher, and the functional form toothpaste for adding active ingredient of Chinese herbs becomes a master in market
Developing direction is flowed, but more existing is not obvious by the effect of toothpaste of active constituent of Chinese medicine.
Dendrobium candidum is to be rich in polysaccharide, dendrobium nobile first of the big mesona of China nine that Taoism regimen classical works " Taoist Scriptures " records
Alkali, free amino acid, vitamin, chlorophyll and various enzymes, external application can stop blooding, promote wound healing.By dendrobium candidum
Active constituent is effectively combined with toothpaste, and disease prevention and the nursing health in oral cavity may be implemented.
Summary of the invention
It is an object of the invention to overcome the above problem, a kind of dendrobium candidum toothpaste is provided, cost of material is low, and formula is simple
Science, the effect of giving full play to dendrobium candidum effective component, have preferable application value.
To achieve the above object, the invention adopts the following technical scheme:
A kind of dendrobium candidum toothpaste includes following components: 5~15 parts of dendrobium candidum extract, moisturizer in parts by weight
40~50 parts, 15~20 parts of rubbing agent, 0.1~0.3 part of preservative, 0.5~1.0 part of binder, 2.0~3.0 parts of foaming agent, sweet tea
0.2~0.5 part of taste agent, 10~15 parts of Dental Erosion nursing compositions, 10~25 parts of deionized water.
Preferably, moisturizer is the mixture of one or more of sorbierite, glycerol, propylene glycol composition.
Preferably, rubbing agent is the mixture of one or both of longan seed powder or Herba Euphorbiae Humifusae powder composition, powder
Size be 500~1000 mesh.
Preferably, preservative is the mixed of one or more of isothiazolinone, paraben esters, potassium sorbate composition
Close object.
Preferably, Dental Erosion nursing compositions include hydroxyapatite, micron order magnesium powder, metal fluoride, borax, weight
Number is as follows: 20~40 parts of hydroxyapatite, 15~45 parts of micron order magnesium powder, 5~15 parts of metal fluoride, borax 20~25
Part, the size of micron order magnesium powder is 80~120 μm.
Preferably, the extracting method of dendrobium candidum extract are as follows: fresh dendrobium candidum is cleaned, peeling, dissection, by 0.5g/L
Solid-liquid ratio distilled water immersion 1h is added, filtered through gauze obtains first-time filtrate and filter residue, and filter residue is added by the solid-liquid ratio of 0.35g/L to be steamed
Distilled water is heated to reflux 3h, and filtered through gauze obtains secondary filtrate, merges resulting filtrate twice, is centrifuged to obtain supernatant, is concentrated under reduced pressure, very
Vacuum freecing-dry, obtains dendrobium candidum extract, and cryo-conservation is spare.
The present invention also provides a kind of methods for preparing the dendrobium candidum toothpaste, comprising the following steps:
A. it is sintered, by the compacting of Dental Erosion nursing compositions, sintering, disinfection, drying, obtains sintered body；
B. sintered body, binder, foaming agent and abrasive are uniformly mixed, obtain powder mixture；
C. dendrobium candidum extract, moisturizer, preservative, sweetener and deionized water are uniformly mixed, make solid matter
Sufficiently dissolution, obtains liquid mixture；
D. powder mixture and liquid mixture are uniformly mixed, grinding, vacuum suction obtain dendrobium candidum toothpaste.
After adopting the above technical scheme, the invention has the following advantages:
1. the effect of giving full play to dendrobium candidum effective component；
2. simple process, low in cost, formula science, cost performance is high；
3. rubbing agent uses natural component, injury of teeth and bleeding gums are avoided.
Specific embodiment
It is right combined with specific embodiments below in order to make those skilled in the art more fully understand technical solution of the present invention
The present invention is described in further detail.
Embodiment one
Present embodiment discloses a kind of dendrobium candidum toothpaste, in parts by weight include following components: dendrobium candidum extract
15 parts, 50 parts of moisturizer, 20 parts of rubbing agent, 0.3 part of preservative, 1.0 parts of binder, 3.0 parts of foaming agent, 0.5 part of sweetener, tooth
15 parts of tooth restoration care ingredient, 10 parts of deionized water.
Moisturizer of the present invention is glycerol, and rubbing agent is the longan seed powder having a size of 1000 mesh, and preservative is isothiazoline
The mixture that ketone, paraben esters, potassium sorbate form, Dental Erosion nursing compositions include hydroxyapatite, micron order magnesium powder, gold
Belong to fluoride, borax, parts by weight are as follows: 40 parts of hydroxyapatite, 45 parts of the magnesium powder having a size of 80 μm, metal fluoride 15
Part, 25 parts of borax.The extracting method of dendrobium candidum extract are as follows: fresh dendrobium candidum is cleaned, peeling, dissection, by 0.5g/L's
Distilled water immersion 1h is added in solid-liquid ratio, and filtered through gauze obtains first-time filtrate and filter residue, and distillation is added by the solid-liquid ratio of 0.35g/L in filter residue
Water is heated to reflux 3h, and filtered through gauze obtains secondary filtrate, merges resulting filtrate twice, is centrifuged to obtain supernatant, is concentrated under reduced pressure, vacuum
Freeze-drying, obtains dendrobium candidum extract, cryo-conservation is spare.
Embodiment two
Present embodiment discloses a kind of dendrobium candidum toothpaste, in parts by weight include following components: dendrobium candidum extract
10 parts, 45 parts of moisturizer, 18 parts of rubbing agent, 0.2 part of preservative, 0.5 part of binder, 2.5 parts of foaming agent, 0.3 part of sweetener, tooth
12 parts of tooth restoration care ingredient, 15 parts of deionized water.
Moisturizer of the present invention is sorbierite, and rubbing agent is the humid euphorbia grass meal end having a size of 800 mesh, and preservative is sorbic acid
Potassium, Dental Erosion nursing compositions include hydroxyapatite, micron order magnesium powder, metal fluoride, borax, and parts by weight are as follows: hydroxyl
30 parts of base apatite, 30 parts of the magnesium powder having a size of 100 μm, 10 parts of metal fluoride, 20 parts of borax.Dendrobium candidum extract mentions
Take method are as follows: fresh dendrobium candidum is cleaned, peeling, dissection, and distilled water immersion 1h, filtered through gauze is added by the solid-liquid ratio of 0.5g/L
First-time filtrate and filter residue are obtained, filter residue is added distilled water by the solid-liquid ratio of 0.35g/L and is heated to reflux 3h, and filtered through gauze obtains secondary filter
Liquid merges resulting filtrate twice, is centrifuged to obtain supernatant, is concentrated under reduced pressure, vacuum freeze drying obtains dendrobium candidum extract, low
Temperature saves backup.
Embodiment three
Present embodiment discloses a kind of dendrobium candidum toothpaste, in parts by weight include following components: dendrobium candidum extract 5
Part, 40 parts of moisturizer, 15 parts of rubbing agent, 0.1 part of preservative, 0.8 part of binder, 2.0 parts of foaming agent, 0.2 part of sweetener, tooth
10 parts of restoration care ingredient, 25 parts of deionized water.
Moisturizer of the present invention is sorbierite and the mixture that propylene glycol forms, and rubbing agent is the longan seed having a size of 500 mesh
The mixture of powder and Herba Euphorbiae Humifusae powder constituent, preservative are isothiazolinone, and Dental Erosion nursing compositions include hydroxy-apatite
Stone, micron order magnesium powder, metal fluoride, borax, parts by weight are as follows: 20 parts of hydroxyapatite, having a size of 80 μm of magnesium powders 15
Part, 5 parts of metal fluoride, 25 parts of borax.The extracting method of dendrobium candidum extract are as follows: fresh dendrobium candidum is cleaned, and peeling is cut
Distilled water immersion 1h is added by the solid-liquid ratio of 0.5g/L in section, and filtered through gauze obtains first-time filtrate and filter residue, and filter residue is by 0.35g/L's
Solid-liquid ratio is added distilled water and is heated to reflux 3h, and filtered through gauze obtains secondary filtrate, merges resulting filtrate twice, is centrifuged to obtain supernatant
Liquid is concentrated under reduced pressure, and vacuum freeze drying obtains dendrobium candidum extract, and cryo-conservation is spare.
Example IV
Present embodiment discloses the methods of the dendrobium candidum toothpaste described in embodiment one to three, comprising the following steps:
1. the compacting of Dental Erosion nursing compositions, sintering, disinfection, drying are obtained sintered body by sintering；
2. sintered body, binder, foaming agent and abrasive are uniformly mixed, powder mixture is obtained；
3. dendrobium candidum extract, moisturizer, preservative, sweetener and deionized water are uniformly mixed, make solid matter
Sufficiently dissolution, obtains liquid mixture；
4. powder mixture and liquid mixture are uniformly mixed, grinding, vacuum suction obtain dendrobium candidum toothpaste.
Performance detection
Performance detection is carried out to the product of embodiment one to three, the results are shown in Table 1, meets GB/T8372-2017.
The detection of 1 properties of product of table
Dendrobium candidum toothpaste of the present invention can not only effectively clean oral cavity, moreover it is possible to give full play to the medicine of dendrobium candidum
Health-care effect is imitated, has the effect of that clearing stomach is promoted the production of body fluid, resolving sputum preventing or arresting vomiting, detumescence is stopped blooding and fresh breath.
Efficacy evaluation
Treatment method: canker sore patient 60 are chosen, male 30, female 30, extent is suitable, uses embodiment one
Product treated.Patient first gargles before treating, and to keep oral cleaning, the product of ulcer surface is then blotted with sterilized cotton ball
The product of embodiment one is finally equably coated on ulcer surface by liquid, gently pressed with wet cotton balls it is even, after meal daily and before sleeping
Treated, 5 days by a definite date, at the end of carry out efficacy evaluation.
Efficacy assessment standard:
Effective: up to 75% or more, pain disappears ulcer healing rate, and ulcer surrounding tissue mucous hyperemia subsides, and ulcer surface has
Newborn epithelium covering.
Effective: for ulcer healing rate up to 50~75%, pain is substantially reduced, and ulcer surrounding tissue mucous hyperemia subsides.
Invalid: ulcer healing rate is lower than 50%, and local pain slightly mitigates or nothing is substantially change.
It is calculated with effective and effective case efficient.
Therapeutic effect
Effective number of cases is 40, and effective number of cases is 15, and invalid number of cases is 5, and effective percentage is 91.7%.
Illustrate in above data, after dendrobium candidum toothpaste of the present invention, for the curative effect of canker sore
Clearly.
Above-described is only some embodiments of the present invention.For those of ordinary skill in the art, not
Under the premise of being detached from the invention design, various modifications and improvements can be made, these belong to protection model of the invention
It encloses.
Claims (7)
1. a kind of dendrobium candidum toothpaste, which is characterized in that in parts by weight include following components: dendrobium candidum extract 5~15
Part, 40~50 parts of moisturizer, 15~20 parts of rubbing agent, 0.1~0.3 part of preservative, 0.5~1.0 part of binder, foaming agent 2.0
~3.0 parts, 0.2~0.5 part of sweetener, 10~15 parts of Dental Erosion nursing compositions, 10~25 parts of deionized water.
2. a kind of dendrobium candidum toothpaste according to claim 1, which is characterized in that moisturizer is sorbierite, glycerol, the third two
The mixture of one or more of alcohol composition.
3. a kind of dendrobium candidum toothpaste according to claim 1, which is characterized in that rubbing agent is longan seed powder or humid euphorbia
The mixture of one or both of grass meal end composition, the size of powder are 500~1000 mesh.
4. a kind of dendrobium candidum toothpaste according to claim 1, which is characterized in that preservative is isothiazolinone, Ni Bo
The mixture of one or more of golden ester, potassium sorbate composition.
5. a kind of dendrobium candidum toothpaste according to claim 1, which is characterized in that Dental Erosion nursing compositions include hydroxyl
Apatite, micron order magnesium powder, metal fluoride, borax, parts by weight are as follows: 20~40 parts of hydroxyapatite, micron order magnesium powder
15~45 parts, 5~15 parts of metal fluoride, 20~25 parts of borax, the size of micron order magnesium powder are 80~120 μm.
6. a kind of dendrobium candidum toothpaste according to claim 1, which is characterized in that the extracting method of dendrobium candidum extract
Are as follows: fresh dendrobium candidum is cleaned, peeling, dissection, distilled water immersion 1h is added by the solid-liquid ratio of 0.5g/L, filtered through gauze obtains once
Filtrate and filter residue, filter residue are added distilled water by the solid-liquid ratio of 0.35g/L and are heated to reflux 3h, and filtered through gauze obtains secondary filtrate, merges
Resulting filtrate twice is centrifuged to obtain supernatant, is concentrated under reduced pressure, and vacuum freeze drying obtains dendrobium candidum extract, and cryo-conservation is standby
With.
7. a kind of method for preparing the dendrobium candidum toothpaste as described in claim 1~6 any one, which is characterized in that including
Following steps:
A. it is sintered, by the compacting of Dental Erosion nursing compositions, sintering, disinfection, drying, obtains sintered body；
B. sintered body, binder, foaming agent and abrasive are uniformly mixed, obtain powder mixture；
C. dendrobium candidum extract, moisturizer, preservative, sweetener and deionized water are uniformly mixed, keep solid matter abundant
Dissolution, obtains liquid mixture；
D. powder mixture and liquid mixture are uniformly mixed, grinding, vacuum suction obtain dendrobium candidum toothpaste.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811126879.9A CN108938524A (en) | 2018-09-26 | 2018-09-26 | A kind of dendrobium candidum toothpaste and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811126879.9A CN108938524A (en) | 2018-09-26 | 2018-09-26 | A kind of dendrobium candidum toothpaste and preparation method thereof |
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| CN108938524A true CN108938524A (en) | 2018-12-07 |
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| CN201811126879.9A Withdrawn CN108938524A (en) | 2018-09-26 | 2018-09-26 | A kind of dendrobium candidum toothpaste and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110051596A (en) * | 2019-04-24 | 2019-07-26 | 武汉科技大学 | A kind of dendrobium nobile toothpaste of antibacterial anti-inflammatory |
| CN113736608A (en) * | 2021-09-09 | 2021-12-03 | 贵州省林业科学研究院 | Preparation method of dendrobe wine and extraction tank for preparing dendrobe wine stock solution |
-
2018
- 2018-09-26 CN CN201811126879.9A patent/CN108938524A/en not_active Withdrawn
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110051596A (en) * | 2019-04-24 | 2019-07-26 | 武汉科技大学 | A kind of dendrobium nobile toothpaste of antibacterial anti-inflammatory |
| CN110051596B (en) * | 2019-04-24 | 2022-05-17 | 武汉科技大学 | Antibacterial and anti-inflammatory dendrobium toothpaste |
| CN113736608A (en) * | 2021-09-09 | 2021-12-03 | 贵州省林业科学研究院 | Preparation method of dendrobe wine and extraction tank for preparing dendrobe wine stock solution |
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Application publication date: 20181207 |
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