CN115554195A - Composition for promoting eyebrow growth and preparation method thereof - Google Patents
Composition for promoting eyebrow growth and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a composition for promoting eyebrow growth, which comprises the following components in percentage by weight: 10-35% of a traditional Chinese medicine composition, 5-20% of a compound nutritional conditioner, 1.0-1.5% of a humectant, 1.0-2.5% of azone, a proper amount of preservative and deionized water; the invention takes effect by the traditional Chinese medicine composition and the compound nutrition conditioner together, and the compound nutrition conditioner is mainly used for supplementing amino acid necessary for hair growth and promoting collagen synthesis. The combined extract achieves the purposes of promoting the growth, thickening and blackening of eyebrows by activating hair follicles in a resting stage, dredging hair growth channels, improving hair follicle microcirculation and supplementing nutrition required by hair growth, and has no irritation to skin, obvious effect, safety and reliability.
Description
Technical Field
The invention belongs to the field of daily chemicals, and particularly relates to a composition for promoting eyebrow growth and a preparation method thereof.
Technical Field
Eyebrows are important components of personal image, quality and beauty, and black eyebrows with good color and luster and beautiful appearance are commonly pursued by beauty lovers. Meanwhile, eyebrows are also an important protective barrier for a human body, the eyebrows not only set off beauty of face eyes, but also play an important role in protecting eye health, and can shield sweat or rainwater from flowing into eyes, so that cornea and conjunctiva are prevented from being stimulated, and keratitis or conjunctivitis is prevented from being generated. At present, the problems of eyebrow falling, sparseness, breakage, unevenness, dull color, asymmetric eyebrow shape and the like are troubled by a plurality of beauty lovers. Therefore, various methods for modifying, protecting and promoting the growth of eyebrows are in force. Various techniques for beautifying and decorating eyebrows and promoting the growth of eyebrows, such as eyebrow tattooing, eyebrow waving, eyebrow planting and the like, are continuously generated, but are far from healthy eyebrows which grow naturally, and the methods are only an ineffectual choice and remedy to the eyebrow problems.
According to research, the factors affecting eyebrows are many and are closely related to the aspects of heredity, nutrition, health condition and the like. The earliest medical book of classic "Huangdi's classic", which exists in China, has pointed out: for eyebrow beauty, the pulse of foot-Taiyang is much blood and qi, which may cause eyebrow burning, and little blood and qi. ". The eyebrow is thick, dense and moist, which reflects the exuberant blood and qi; conversely, thin, short, thin and withered eyebrows reflect deficiency of qi and blood. The eyebrows fall off and are thin and loose, so it is often seen in weak qi and blood and weak body. Eyebrows are also easily dropped in patients with hypothyroidism and anterior pituitary hypofunction. It has been reported that in male pattern alopecia, the hair cycle changes, the diameter of hair follicles decreases, the anagen phase of hair follicles shortens, the telogen phase extends, the hair length as a whole is short, and at the same time, the hair follicles are miniaturized to change large colored hairs into short and fine colorless hairs. Eyebrows are similar to hair loss, and treatment is consistent, for example, topical application of minoxidil liniment can promote eyebrow growth and treat seborrheic alopecia. However, minoxidil causes some obvious side effects, and thus, the number of people who actually use minoxidil is not large.
At present, chinese herbal medicine extracts are adopted in China to prevent alopecia and grow hair, and a plurality of products are researched, but few researches are made on promoting the growth of eyebrows, and targeted products are fewer.
Disclosure of Invention
The invention aims to provide a composition for promoting eyebrow growth, which has quick response and obvious effect, by combining the traditional Chinese medicine composition and the supplement of a compound nutrition conditioner based on the traditional Chinese medicine and nutriology principles; the invention also aims to provide a preparation method of the composition for promoting the growth of eyebrows.
The invention is realized by the following technical scheme: a composition for promoting eyebrow growth comprises the following components in percentage by weight: 10-35% of a traditional Chinese medicine composition, 5-20% of a compound nutritional conditioner, 1.0-1.5% of a humectant, 1.0-2.5% of azone, a proper amount of preservative and deionized water;
the traditional Chinese medicine composition comprises the following components in percentage by weight: 8-20% of salvia miltiorrhiza, 5-15% of pine needle, 5-20% of glossy privet fruit, 5-15% of ligusticum chuanxiong hort, 5-25% of polygonum multiflorum, 5-15% of astragalus membranaceus, 10-20% of semen cuscutae, 5-15% of cortex mori radicis and 5-15% of garden balsam stem.
In the traditional Chinese medicine composition, the glossy privet fruit, the tuber fleeceflower root, the white mulberry root-bark, the garden balsam stem, the astragalus root and the dodder seed are deionized water extracts, and the pine needle, the ligusticum chuanxiong hort and the salvia miltiorrhiza are ethanol extracts.
The compound nutrition conditioner consists of the following components in percentage by weight: 10-30% of dictyophora phalloidea extract, 2-10% of VC derivative, 2-10% of panthenol and 5-10% of ginseng extract.
Preferably, the traditional Chinese medicine composition comprises the following substances in percentage by weight: 15% of salvia miltiorrhiza, 10% of pine needles, 12% of glossy privet fruit, 10% of ligusticum chuanxiong hort, 12% of polygonum multiflorum, 10% of astragalus membranaceus, 12% of semen cuscutae, 9% of cortex mori radicis and 10% of garden balsam stem.
The compound nutrition regulator comprises the following substances in percentage by weight: 25% of dictyophora phalloidea extract, 8% of VC derivative, 8% of panthenol and 9% of ginseng extract.
Preferably, the traditional Chinese medicine composition comprises the following substances in percentage by weight: 13% of salvia miltiorrhiza, 9% of pine needles, 13% of glossy privet fruit, 12% of ligusticum chuanxiong hort, 14% of polygonum multiflorum, 9% of astragalus membranaceus, 10% of semen cuscutae, 10% of cortex mori radicis and 10% of garden balsam stem.
The nutritional regulator comprises the following substances in percentage by weight: 18% of dictyophora phalloidea extract, 7% of VC derivative, 6% of panthenol and 7% of ginseng extract.
Preferably, the traditional Chinese medicine composition comprises the following substances in percentage by weight: 16% of salvia miltiorrhiza, 8% of pine needles, 10% of glossy privet fruit, 11% of ligusticum chuanxiong hort, 16% of polygonum multiflorum, 8% of astragalus membranaceus, 14% of semen cuscutae, 8% of cortex mori radicis and 9% of garden balsam stem.
The nutritional regulator comprises the following substances in percentage by weight: 16% of dictyophora indusiata extract, 9% of VC derivative, 5% of panthenol and 8% of ginseng extract.
The preparation method of the traditional Chinese medicine extracted from the pine needles, the ligusticum chuanxiong hort and the salvia miltiorrhiza with ethanol comprises the following steps:
heating and drying the pine needles, the ligusticum chuanxiong hort and the salvia miltiorrhiza to constant mass, crushing, sieving, mixing according to the weight percentage, adding 75% ethanol, heating, refluxing and extracting for 2 hours, filtering to obtain an extracting solution, repeatedly extracting residues for 1 time, combining filtrates, concentrating the extracting solution under reduced pressure, and drying to obtain the extracts of the pine needles, the ligusticum chuanxiong hort and the salvia miltiorrhiza.
The preparation method of the deionized water extracts of glossy privet fruit, tuber fleeceflower root, white mulberry root-bark, garden balsam stem, astragalus and south dodder seed comprises the following steps:
respectively heating and drying fructus Ligustri Lucidi, polygoni Multiflori radix, cortex Mori, herba Speranskiae Tuberculatae, radix astragali and semen Cuscutae, pulverizing, mixing according to weight percentage, adding deionized water, decocting for 2-2.5 hr, filtering to obtain extractive solution, decocting the residue with water for 1 time, mixing filtrates, and concentrating under reduced pressure.
The preparation method of the bamboo fungus extract comprises the following steps:
taking dried dictyophora indusiata, crushing and sieving with a 20-mesh sieve, dissolving dictyophora indusiata dry powder in water, adding a compound enzyme system consisting of protease, cellulase, hemicellulase and pectinase according to a certain proportion, performing enzymolysis treatment to obtain a dictyophora indusiata extract containing amino acid, polypeptide, small peptide and polysaccharide, and concentrating under reduced pressure for later use.
The dictyophora indusiata can be stipes and sheds of the dictyophora indusiata and can also be waste stipes and sheds of commercial dictyophora indusiata, the weight of the stipes and the sheds is more than 1.4 times of that of edible stipes and sheds, and the resources are rich. The cost can be greatly reduced by adopting the bacterium trays and the bacterium covers, and waste is changed into valuable.
The VC derivative is VC phosphate magnesium or VC phosphate sodium. The composition also comprises a humectant and a preservative.
The humectant consists of sodium hyaluronate and propylene glycol.
The preservative is prepared by compounding two or more of phenoxyethanol, IPBC, p-hydroxybenzoate and menthol.
The invention also provides a preparation method of the composition for promoting eyebrow growth, which is characterized by sequentially comprising the following steps:
(1) Preparing a traditional Chinese medicine composition, mixing the obtained glossy privet fruit, polygonum multiflorum, white mulberry root-bark, garden balsam stem, astragalus membranaceus, semen cuscutae, pine needle, ligusticum chuanxiong hort and salvia miltiorrhiza extracts according to the weight percentage of traditional Chinese medicines in the composition, dissolving and uniformly mixing with a proper amount of deionized water, and filtering to obtain a clear solution for later use;
(2) Preparing the composite nutrition conditioner. According to the weight percentage of the composite nutrition conditioner in the composition, dissolving the dictyophora indusiata extract in a proper amount of deionized water, sequentially adding the VC derivative, the ginseng extract and panthenol, uniformly stirring, and fixing the volume by using the deionized water for later use;
(3) Adding the compound nutritional conditioner into the traditional Chinese medicine composition solution, and uniformly mixing to obtain a combined solution;
(4) Adding 1.0-1.5% of humectant into the combined solution obtained in the step (3), uniformly mixing, and adding 1.0-2.5% of azone and preservative, wherein the content can be adjusted by a person skilled in the art;
(5) And (4) performing constant volume on the solution obtained in the step (4) by using deionized water, and finally obtaining the composition which contains 10-35% of the traditional Chinese medicine composition and 5-20% of the composite nutritional conditioner and is used for promoting the growth of eyebrows. The skilled person can understand and operate according to the described procedures.
The polygonum multiflorum is a good medicine for treating alopecia, has the effects of nourishing yin and tonifying kidney, nourishing liver and blood, blackening beard and hair and strengthening muscles and bones, mainly comprises stilbene glycoside compounds, anthraquinone compounds and polymeric procyanidine, and the procyanidine can inhibit the activity of negative hair growth regulatory factors (TGF-beta) so as to promote hair growth. The glossy privet fruit not only influences important cell factors in the hair growth promoting process, but also can reduce the androgen level, thereby playing the roles of promoting hair growth and maintaining the hair follicle morphology. The salvia miltiorrhiza contains various components, the tanshinone, the salvianolic acid and other substances in the salvia miltiorrhiza have the functions of activating blood and removing stasis, have obvious effects on the aspects of oxidation resistance, antibiosis and anti-inflammation, regulation of tissue repair and regeneration, whitening and the like, and are one of the botanical drugs with definite effects proved by research. The cortex mori extract can shorten the resting period of hair and induce hair follicles in the growth period, and clinical tests prove that the cortex mori extract has a good effect on male alopecia. The semen cuscutae is mainly composed of flavonoid compounds, is an essential drug for warming and invigorating kidney yang, and can stimulate hair papilla to secrete Hepatocyte Growth Factor (HGF) to promote the growth of hair follicles, and HGF is a multifunctional growth factor secreted by various cells in vivo. Pine needles are recorded in herbs of all generations, and the book Biyu means that it is responsible for eczema, hair growth and five internal organs. The record of the compendium of materia medica records that pine needles are bitter in taste and warm in flavor, are nontoxic, are not old after being taken for a long time, are light in weight and benefit qi, and are mainly used for treating eczema. Hair growing, five zang organs in the middle, no hunger and life prolonging. In addition, the pine needles contain 17 amino acids, wherein the pine needles comprise 8 amino acids necessary for human bodies, and the content of 4 amino acids such as methionine, tryptophan, lysine, phenylalanine and the like is the highest, and accounts for 73.4% -94.5% of the total amount of the necessary amino acids. Radix astragali has effects of dilating blood vessel, improving blood circulation, and promoting hair growth. Dodder has the functions of tonifying kidney, securing essence, nourishing liver, improving eyesight and estrogen-like activity, and can promote the growth of hair follicles by stimulating HGF secretion from hair papilla. The garden balsam stem has the effects of dispelling wind and removing dampness, and promoting blood circulation and removing obstruction in channels, and has strong penetrating power and can directly reach the deep part of hair follicles. The volatile oil of rhizoma Ligustici Chuanxiong can significantly increase skin blood flow to promote penetration by stimulating skin.
The compound nutritional conditioner is mainly used for supplementing essential amino acids for hair growth and promoting collagen synthesis. The bamboo fungus contains 21 kinds of amino acids, especially cystine with high lysine and arginine content, cystine as one kind of rare amino acid and important hair forming amino acid, 8 kinds of essential amino acids accounting for 40% of the total amino acids, and different parts of bamboo fungus have basically the same amino acid forming structure, and may be hydrolyzed to obtain various amino acids, polypeptide and polysaccharide favorable to providing hair material.
The traditional Chinese medicine composition and the compound nutrition conditioner play roles together, and the traditional Chinese medicine composition activates hair follicles in a resting period, dredges hair growth channels, improves hair follicle microcirculation, and supplements nutrition required by hair growth, so that the purposes of promoting eyebrow growth, thickening and blackening are achieved, and the traditional Chinese medicine composition has no irritation to skin, and is obvious in effect, safe and reliable.
Detailed Description
The present invention is further described with reference to the following specific embodiments, but the embodiments are only further description of the present invention, and those skilled in the art can make equivalent substitutions for the present invention with the spirit of the present invention, and fall within the protection scope of the present invention.
Example 1
A composition for promoting eyebrow growth comprises the following components in percentage by weight: the traditional Chinese medicine composition consists of 32 percent of traditional Chinese medicine composition, 10 percent of compound nutrition conditioner, 1.2 percent of humectant, 1.8 percent of azone, a proper amount of preservative and deionized water;
the traditional Chinese medicine composition comprises the following components in percentage by weight: 15% of salvia miltiorrhiza, 10% of pine needles, 12% of glossy privet fruit, 10% of ligusticum chuanxiong hort, 12% of polygonum multiflorum, 10% of astragalus membranaceus, 12% of semen cuscutae, 9% of cortex mori radicis and 10% of garden balsam stem.
The compound nutritional conditioner comprises the following substances in percentage by weight: 25% of dictyophora phalloidea extract, 8% of VC derivative, 8% of panthenol and 9% of ginseng extract.
In the Chinese medicinal composition, the glossy privet fruit, the tuber fleeceflower root, the white mulberry root-bark, the garden balsam stem, the astragalus root and the dodder seed are deionized water extracts, and the pine needle, the ligusticum chuanxiong hort and the salvia miltiorrhiza are ethanol extracts.
The preparation method of the deionized water extracts of glossy privet fruit, tuber fleeceflower root, white mulberry root-bark, garden balsam stem, astragalus and south dodder seed comprises the following steps:
mixing heated and dried fructus Ligustri Lucidi, polygoni Multiflori radix, cortex Mori, herba Speranskiae Tuberculatae, radix astragali and semen Cuscutae, adding deionized water, decocting for 2 hr, filtering to obtain filtrate, decocting the residue with water for 1 time, filtering, mixing the filtrates, and concentrating under reduced pressure to obtain dry powder, i.e. Chinese medicinal extract.
The preparation method of the traditional Chinese medicine extracted from the pine needles, the ligusticum chuanxiong hort and the salvia miltiorrhiza with ethanol comprises the following steps:
pulverizing folium Pini, rhizoma Ligustici Chuanxiong and Saviae Miltiorrhizae radix, heating and drying to constant mass, sieving with 20 mesh sieve, mixing the powders according to weight parts, adding 4-6 times of 60-80% ethanol, heating and reflux extracting, filtering to obtain filtrate, extracting the residue for 1 time, mixing the filtrates, concentrating under reduced pressure, and drying to obtain ethanol extract of folium Pini, rhizoma Ligustici Chuanxiong and Saviae Miltiorrhizae radix.
The preparation method of the bamboo fungus extract comprises the following steps:
taking dried dictyophora indusiata, crushing, sieving with a 20-mesh sieve, dissolving the dictyophora indusiata dry powder with water, adding a compound enzyme system consisting of protease, cellulase, hemicellulase and pectinase according to an activity unit proportion of 4.
The bamboo fungus can be stipe and sheds of the bamboo fungus, and can also be waste truestal and pileus of commercial bamboo fungus.
The VC derivative is VC phosphate magnesium or VC phosphate sodium.
The composition further comprises a humectant, azone, and a preservative.
The humectant consists of sodium hyaluronate and propylene glycol, and the proportion (W/V) of the sodium hyaluronate and the propylene glycol is 1:1.
The preservative is prepared by compounding 0.8 percent of phenoxyethanol and 0.03 percent of IPBC.
A method for preparing a composition for promoting eyebrow growth sequentially comprises the following steps:
(1) Preparing the traditional Chinese medicine composition solution. According to the weight percentage of the traditional Chinese medicines in the composition, the mixed extract of the glossy privet fruit, the tuber fleeceflower root, the white mulberry root-bark, the garden balsam stem, the astragalus root, the south dodder seed, the pine needle, the ligusticum chuanxiong hort and the red sage root is dissolved and uniformly mixed by using a proper amount of deionized water, and a clear solution is obtained by filtering for later use;
(2) Preparing the composite nutrition conditioner solution. According to the weight percentage of the composite nutrition conditioner in the composition, the dictyophora indusiata extract is dissolved in a proper amount of deionized water, VC magnesium phosphate, the ginseng extract and panthenol are sequentially added, the mixture is uniformly stirred, and the volume is determined by the deionized water for standby;
(3) Adding the composite nutritional conditioner solution into the traditional Chinese medicine composition solution, and fully and uniformly mixing to obtain a combined solution;
(4) Adding a humectant into the combined solution obtained in the step (3) to a final concentration of 1.2%, uniformly mixing, adding azone and a preservative, and fully and uniformly mixing, wherein the humectant can be adjusted by a person skilled in the art;
(5) And (4) performing constant volume on the solution obtained in the step (4) by using deionized water, and finally obtaining the composition which contains 35% of the traditional Chinese medicine composition and 20% of the compound nutritional conditioner and is used for promoting the growth of eyebrows. The skilled person can understand and operate according to the described procedures.
Example 2
A composition for promoting eyebrow growth comprises the following components in percentage by weight: the traditional Chinese medicine composition comprises 18% of a compound nutrition conditioner, 15% of a humectant, 1.0% of azone, a proper amount of a preservative and deionized water;
the traditional Chinese medicine composition comprises the following components in percentage by weight: 13% of salvia miltiorrhiza, 9% of pine needles, 13% of glossy privet fruit, 12% of ligusticum chuanxiong hort, 14% of polygonum multiflorum, 9% of astragalus membranaceus, 10% of semen cuscutae, 10% of cortex mori radicis and 10% of garden balsam stem.
The nutritional regulator comprises the following substances in percentage by weight: 18% of dictyophora phalloidea extract, 7% of VC derivative, 6% of panthenol and 7% of ginseng extract.
In the traditional Chinese medicine composition, the glossy privet fruit, the tuber fleeceflower root, the white mulberry root-bark, the garden balsam stem, the astragalus root and the dodder seed are deionized water extracts, and the pine needle, the ligusticum chuanxiong hort and the salvia miltiorrhiza are ethanol extracts. The extraction method was the same as in example 1.
The preparation method of the dictyophora indusiata extract is the same as that of the example 1.
The VC derivative is VC phosphate magnesium or VC phosphate sodium.
The composition also comprises a humectant and a preservative.
The humectant consists of sodium hyaluronate and propylene glycol, and the proportion (W/V) of the sodium hyaluronate and the propylene glycol is 3:2.
The preservative consists of phenoxyethanol (0.7%) and p-hydroxybenzoate (0.15%).
A method for preparing a composition for promoting eyebrow growth sequentially comprises the following steps:
(1) Preparing the traditional Chinese medicine composition solution. According to the weight percentage of the traditional Chinese medicines in the composition, the mixed extract of the glossy privet fruit, the tuber fleeceflower root, the white mulberry root-bark, the garden balsam stem, the astragalus root, the south dodder seed, the pine needle, the ligusticum chuanxiong hort and the red sage root is dissolved and uniformly mixed by using a proper amount of deionized water, and a clear solution is obtained by filtering for later use;
(2) Preparing the composite nutrition conditioner solution. According to the weight percentage of the composite nutrition conditioner in the composition, the dictyophora indusiata extract is dissolved in a proper amount of deionized water, the VC derivative, the ginseng extract and the panthenol are sequentially added, the mixture is uniformly stirred, and the volume is determined by the deionized water for standby;
(3) Adding the composite nutritional conditioner solution into the traditional Chinese medicine composition solution, and fully and uniformly mixing to obtain a combined solution;
(4) And (4) adding a humectant into the combined solution obtained in the step (3) to obtain a final concentration of 1.0%, uniformly mixing, adding azone and a preservative, and fully and uniformly mixing. The person skilled in the art can adjust it;
(5) And (4) performing constant volume on the solution obtained in the step (4) by using deionized water, and finally obtaining the composition which contains 40% of the traditional Chinese medicine composition and 25% of the compound nutritional conditioner and is used for promoting the growth of eyebrows. The skilled person can understand and operate according to the described procedures.
Example 3
A composition for promoting eyebrow growth comprises the following components in percentage by weight: 24 percent of traditional Chinese medicine composition, 13 percent of compound nutrition conditioner, 1.3 percent of humectant, 2.0 percent of azone, a proper amount of preservative and deionized water;
the traditional Chinese medicine composition comprises the following components in percentage by weight: 16% of salvia miltiorrhiza, 8% of pine needles, 10% of glossy privet fruit, 11% of ligusticum chuanxiong hort, 16% of polygonum multiflorum, 8% of astragalus membranaceus, 14% of semen cuscutae, 8% of cortex mori radicis and 9% of garden balsam stem.
The nutritional regulator comprises the following substances in percentage by weight: 16% of bamboo fungus extract, 9% of VC derivative, 5% of panthenol and 8% of ginseng extract.
In the traditional Chinese medicine composition, the glossy privet fruit, the tuber fleeceflower root, the white mulberry root-bark, the garden balsam stem, the astragalus root and the dodder seed are deionized water extracts, and the pine needle, the ligusticum chuanxiong hort and the salvia miltiorrhiza are ethanol extracts. The extraction method was the same as in example 1.
The preparation method of the dictyophora indusiata extract is the same as that of example 1.
The VC derivative is VC phosphate magnesium or VC phosphate sodium. The composition also comprises a humectant and a preservative.
The humectant consists of sodium hyaluronate and propylene glycol, and the proportion (W/V) of the sodium hyaluronate and the propylene glycol is 3:4.
The preservative is prepared from phenoxyethanol (0.65%), menthol (0.3%) and IPBC (0.02%)
And compounding.
A method for preparing a composition for promoting eyebrow growth sequentially comprises the following steps:
(1) Preparing the traditional Chinese medicine composition solution. According to the weight percentage of the traditional Chinese medicines in the composition, the mixed extract of the glossy privet fruit, the tuber fleeceflower root, the white mulberry root-bark, the garden balsam stem, the astragalus root, the south dodder seed, the pine needle, the ligusticum chuanxiong hort and the red sage root is dissolved and uniformly mixed by using a proper amount of deionized water, and a clear solution is obtained by filtering for later use;
(2) Preparing the composite nutrition conditioner solution. According to the weight percentage of the composite nutrition conditioner in the composition, the dictyophora indusiata extract is dissolved in a proper amount of deionized water, VC magnesium phosphate, the ginseng extract and panthenol are sequentially added, the mixture is uniformly stirred, and the volume is determined by the deionized water for standby;
(3) Adding the composite nutritional conditioner solution into the traditional Chinese medicine composition solution, and fully and uniformly mixing to obtain a combined solution;
(4) Adding a humectant into the combined solution obtained in the step (3) to a final concentration of 1.3%, uniformly mixing, adding azone and a preservative, and fully and uniformly mixing, wherein the humectant can be adjusted by a person skilled in the art;
(5) And (4) performing constant volume on the solution obtained in the step (4) by using deionized water, and finally obtaining the composition which contains 45% of the traditional Chinese medicine composition and 15% of the compound nutritional conditioner and is used for promoting the growth of eyebrows. The skilled person can understand and operate according to the described procedures.
Example 4 effects of use
The product is used for trial of women with fallen eyebrows or sparse and yellow eyebrows, and 80 people participate in the product, and the age is 18-55 years old. The experiment sets 3 example groups and 1 blank control group, each group has 20 persons, random grouping is adopted, the difference between the groups is not significant, wherein the preparation method of the example groups is as follows: the composition prepared in this example was formulated into a 10% deionized water solution and applied to the roots of eyebrows twice a day in the morning and afternoon, with the blank control untreated and the test duration of 90 days. The test data are as follows:
the effect evaluation method comprises the following steps: first, the eyebrow density change (unit: root/cm) was counted using a hair follicle analyzer 2 ) Operate according to the description. After 30 days of use, the eyebrow density of the 3 example groups is significantly improved compared with that of the control group (P<0.05 No significant differences between examples (a) ((ii)) and groupsP>0.05 At day 60 and day 90) after sample application. The eyebrow density increases slowly without obvious difference, which shows that the composition has quick effect and can improve the eyebrow density in a shorter time. The eyebrow density of the sample group was significantly increased compared to that before smearing the sample (P< 0.05); the blank group did not change before and after sample application (P＞0.05)。
The concentration of the protein in the control group,P< 0.05, indicating significant difference
And secondly, adopting a reported evaluation method. Photographing evaluation is carried out 30 days, 60 days and 90 days after smearing, comprehensive judgment is carried out according to the area, the density and the length change of the eyebrows shown in the picture so as to determine the effect, and the test effect after smearing for 90 days is counted as the following table.
Effect judgment standard: a significant improvement, + +++= a moderate improvement, + = a slight improvement, 0= no change, - = a slight decrease, - = a moderate decrease, - - = a significant decrease. Effectively equal to the percentage of the total of +++, ++, + occurrences.
In none of the above tests, the user presented any safety, allergy and irritation problems. The product has obvious effect and quick response. The above results indicate that the composition is a safe and effective eyebrow growth promoter.
Claims (9)
1. The composition for promoting the growth of eyebrows is characterized by comprising the following components in percentage by weight: 10-35% of traditional Chinese medicine composition, 5-20% of compound nutrition conditioner, 1.0-1.5% of humectant, 1.0-2.5% of azone, a proper amount of preservative and deionized water;
the traditional Chinese medicine composition comprises the following components in percentage by weight: 8-20% of salvia miltiorrhiza, 5-15% of pine needle, 5-20% of glossy privet fruit, 3-15% of ligusticum chuanxiong hort, 5-25% of polygonum multiflorum, 5-15% of astragalus membranaceus, 10-20% of semen cuscutae, 3-15% of cortex mori radicis and 5-15% of garden balsam stem;
the composite nutrition conditioner consists of the following components in percentage by weight: 10-30% of dictyophora indusiata extract, 2-10% of VC derivative, 2-10% of panthenol and 5-10% of ginseng extract;
the VC derivative is VC phosphate magnesium or VC phosphate sodium;
the humectant consists of sodium hyaluronate and propylene glycol;
the preservative is prepared by compounding two or more of phenoxyethanol, IPBC, p-hydroxybenzoate and menthol.
2. The composition for promoting eyebrow growth according to claim 1, wherein fructus Ligustri Lucidi, radix Polygoni Multiflori, cortex Mori, herba speranskiae tuberculatae, radix astragali, and semen Cuscutae in the Chinese medicinal composition are deionized water extracts, and folium Pini, rhizoma Chuanxiong, and radix Salviae Miltiorrhizae are ethanol extracts.
3. The composition for promoting eyebrow growth according to claim 2, wherein the ethanol extracts of pine needles, ligusticum chuanxiong hort and salvia miltiorrhiza bunge are prepared by the following steps: heating and drying the pine needles, the ligusticum chuanxiong hort and the salvia miltiorrhiza to constant mass, crushing, sieving, mixing according to the weight percentage, adding 75% ethanol, heating, refluxing and extracting, filtering to obtain an extracting solution, repeatedly extracting residues, combining filtrates, concentrating the extracting solution under reduced pressure, and drying to obtain the extracts of the pine needles, the ligusticum chuanxiong hort and the salvia miltiorrhiza.
4. The composition for promoting the growth of eyebrows, according to claim 2, wherein the deionized water extracts of fructus ligustri lucidi, polygonum multiflorum, cortex mori radicis, speranskia herb, astragalus membranaceus and semen cuscutae are prepared by a method comprising the following steps: respectively heating and drying fructus Ligustri Lucidi, polygoni Multiflori radix, cortex Mori, herba Speranskiae Tuberculatae, radix astragali and semen Cuscutae, pulverizing, mixing according to weight percentage, adding deionized water, decocting, filtering to obtain extractive solution, decocting the residue with water repeatedly, mixing filtrates, and concentrating under reduced pressure to obtain the final product.
5. The composition for promoting the growth of eyebrows, according to claim 2, wherein the dictyophora indusiata extract in the composite nutritional conditioner is prepared by a method comprising the following steps of: pulverizing dried Dictyophora Indusiata, sieving, dissolving with water, adding compound enzyme system composed of protease, cellulase, hemicellulase and pectinase, performing enzymolysis to obtain Dictyophora Indusiata extract containing amino acids, polypeptides and polysaccharides, and concentrating under reduced pressure.
6. The composition for promoting eyebrow growth according to claim 5, wherein the protease, cellulase, hemicellulase and pectinase are present in a unit ratio of 4.
7. The composition for promoting eyebrow growth according to claim 1, wherein said Dictyophora phalloidea is stipe and sheel of Dictyophora phalloidea, or waste truffle and pileus of commercial Dictyophora phalloidea.
8. The composition for promoting the growth of eyebrows in accordance with claim 1, wherein the VC derivative, panthenol and the ginseng extract are commercially available products as cosmetic raw materials.
9. The method for preparing a composition for promoting the growth of eyebrows in accordance with claim 1, comprising the steps of:
(1) Preparing a traditional Chinese medicine composition, mixing the obtained glossy privet fruit, polygonum multiflorum, white mulberry root-bark, garden balsam stem, astragalus, dodder, pine needle, ligusticum chuanxiong hort and salvia miltiorrhiza extracts according to the weight percentage of the traditional Chinese medicines in the composition, dissolving and uniformly mixing with a proper amount of deionized water, and filtering to obtain a clear solution for later use;
(2) Preparing a composite nutrition conditioner, dissolving the dictyophora indusiata extract in a proper amount of deionized water according to the weight percentage of the composite nutrition conditioner in the composition, sequentially adding the VC derivative, the ginseng extract and the panthenol, stirring uniformly, and fixing the volume by using the deionized water to obtain the composite nutrition conditioner;
(3) Adding the composite nutrition conditioner into the traditional Chinese medicine composition solution, and uniformly mixing to obtain a combined solution;
(4) Adding 1.0-1.5% of humectant into the combined solution obtained in the step (3), uniformly mixing, and adding 1.0-2.5% of azone and preservative;
(5) And (4) performing constant volume on the solution obtained in the step (4) by using deionized water, and finally obtaining the composition which contains 10-35% of the traditional Chinese medicine composition and 5-20% of the composite nutritional conditioner and is used for promoting the growth of eyebrows.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1165187A (en) * | 1996-05-10 | 1997-11-19 | 中国科学院大连化学物理研究所 | Method for producing dictyophora indusiata nutritive mycelium using bamboo fungus submerged culture fermentation technology |
| CN107753380A (en) * | 2017-12-08 | 2018-03-06 | 中山市美源化妆品有限公司 | A kind of eyebrow, which increases, promotes formula of liquid |
| CN112401216A (en) * | 2020-11-12 | 2021-02-26 | 贵州省生物研究所 | Preparation method of bamboo fungus sauce |
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2022
- 2022-11-09 CN CN202211400375.8A patent/CN115554195A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1165187A (en) * | 1996-05-10 | 1997-11-19 | 中国科学院大连化学物理研究所 | Method for producing dictyophora indusiata nutritive mycelium using bamboo fungus submerged culture fermentation technology |
| CN107753380A (en) * | 2017-12-08 | 2018-03-06 | 中山市美源化妆品有限公司 | A kind of eyebrow, which increases, promotes formula of liquid |
| CN112401216A (en) * | 2020-11-12 | 2021-02-26 | 贵州省生物研究所 | Preparation method of bamboo fungus sauce |
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| 徐莲等: "黄芪、何首乌、女贞子、菟丝子混合提取物对体外培养毛囊生长的影响及药理作用研究", 《现代生物医学进展》, vol. 14, no. 22, pages 4201 - 4204 * |
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