CN107412709A - Chinese herbal medicine composition with alopecia stopping and hair growth effects and preparation method thereof - Google Patents
Chinese herbal medicine composition with alopecia stopping and hair growth effects and preparation method thereof Download PDFInfo
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- 235000007586 terpenes Nutrition 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 235000019164 vitamin B2 Nutrition 0.000 description 1
- 239000011716 vitamin B2 Substances 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 235000007063 yellowwood Nutrition 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000001841 zingiber officinale Substances 0.000 description 1
Classifications
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Abstract
The invention discloses a Chinese herbal medicine composition with the functions of preventing alopecia and promoting hair growth, which is characterized by comprising the following components in part by weight: the Chinese herbal medicine composition is prepared from the following raw materials in parts by weight: 15-25 parts of clove, 9-18 parts of ginger, 16-22 parts of pepper, 4-9 parts of safflower, 18-25 parts of human, 30-38 parts of lucid ganoderma, 20-40 parts of black sesame, 4-10 parts of white mulberry root-bark, 12-25 parts of ginkgo leaf, 28-40 parts of prepared fleece-flower root, 8-15 parts of mulberry leaf, 22-33 parts of angelica, 24-32 parts of cacumen biotae, 8-12 parts of eclipta alba, 6-12 parts of lophatherum gracile and 12-18 parts of chinquapin herb seed oil. The components of the shampoo containing the Chinese herbal medicines provided by the invention are reasonably and scientifically matched and are mutually synergistic, so that the shampoo has the effects of preventing alopecia, promoting hair growth, sterilizing, inhibiting bacteria, diminishing inflammation and relieving itching.
Description
Technical field
The invention belongs to field of Chinese herbal medicine technology, more particularly to a kind of herbal composite and its system with hair growth accelerating
Preparation Method.
Background technology
The growing state of hair is the important embodiment for reacting modern's physical condition and image, even more healthy living
Important symbol.Due to the frequent use of chemical hair shampoo article, rhythm of life is accelerated, and the influence for the factors such as operating pressure increases, takes off
Hair has turned into Modern human populations one compared with universal phenomenon, annoyings many young and promising personages, is brought to daily life
Many worries.Because alopecia one influences personal image, two have impact on interpersonal relationships, and more serious can also influence alopecia trouble
The psychology of person.At present, the medicine of in the market hair growth hair tonic is more and random, although treatment of the scholars to alopecia has been carried out largely
Research, cause existing trichogen to treat both principal and secondary aspect of disease, not only price is high, and is easily recurred after being discontinued, effect
It is undesirable, or even scalp and hair are compromised, cause hair quality to become worse etc., threatened to our health care belt.
The content of the invention
It is an object of the invention to：For above-mentioned problem, there is provided a kind of Chinese herbal medicine combination with hair growth accelerating
Thing and preparation method thereof, herbal composite of the invention can effectively protect hair quality not injured, make hair difficult for drop-off, can be effective
Improve composition in nutritional ingredient hair care effect.In order to realize foregoing invention purpose, the technical solution adopted by the present invention is such as
Under：
According to an aspect of the present invention, there is provided a kind of herbal composite with hair growth accelerating, the Chinese herbal medicine combination
Thing is formulated by the raw material of following parts by weight：15~25 parts of cloves, 9~18 parts of ginger, 16~22 parts of Chinese prickly ash, safflower 4~9
Part, 18~25 parts of life, 30~38 parts of ganoderma lucidum, 20~40 parts of Semen sesami nigrum, 4~10 parts of the root bark of white mulberry, 12~25 parts of ginkgo leaf, nine systems
28~40 parts of the fleece-flower root, 8~15 parts of mulberry leaf, 22~33 parts of Radix Angelicae Sinensis, 24~32 parts of cacumen biotae, 8~12 parts of Eclipta prostrata, lophatherum gracile 6
~12 parts and white 10~20 parts of pond flower seed oil.
Preferably, the herbal composite is formulated by the raw material of following parts by weight：22 parts of cloves, 14 parts of ginger,
20 parts of Chinese prickly ash, 7 parts of safflower, 21 parts of life, 34 parts of ganoderma lucidum, 32 parts of Semen sesami nigrum, 8 parts of the root bark of white mulberry, 18 parts of ginkgo leaf, prepared fleece flower root 35
15 parts of part, 12 parts of mulberry leaf, 28 parts of Radix Angelicae Sinensis, 29 parts of cacumen biotae, 10 parts of Eclipta prostrata, 9 parts of lophatherum gracile and white pond flower seed oil.
According to another aspect of the present invention, there is provided a kind of preparation method of the herbal composite with hair growth accelerating,
Comprise the following steps：
(1) raw material is taken by following parts by weight respectively：Cloves, ginger, Chinese prickly ash, safflower, life, ganoderma lucidum, Semen sesami nigrum, Sang Bai
Skin, ginkgo leaf, prepared fleece flower root, mulberry leaf, Radix Angelicae Sinensis, cacumen biotae, Eclipta prostrata, lophatherum gracile and Bai Chi flower seed oils；
(2) cloves, life, ganoderma lucidum, the root bark of white mulberry, prepared fleece flower root and Radix Angelicae Sinensis are crushed respectively, then mixed
Particle A is closed, 1h~3h is added water to cook in particle A is mixed, is cooled to after temperature is 28 DEG C~35 DEG C and obtains decocting mixed material
Liquid A1, it then will decoct mixture feed liquid A1 and be put into during traditional Chinese medicine extraction fills and add the ethanol that concentration is 70%~80%, in temperature
Spend and decoct 1h~1.5h to carry out heating after sealing immersion 20h~48h under the conditions of 35 DEG C~45 DEG C, refilter to obtain filtered fluid
A2, the ethanol that 5 times~8 times are added into filter residue are filtrated to get filtered fluid A3 again again through decoction 2h~3h, will be obtained above
Filtered fluid A2 and filtered fluid A3 merging, thickening filtration 1 time~3 times, the white pond flower seed oil of 2/5 amount of addition is mixed evenly and mistake
Filter 1 time~2 times, obtains the first hybrid filtering liquid, standby；
(3) ginger, Chinese prickly ash, safflower warm water are cleaned up respectively, ginger is cut into 0.5mm~1.5mm fragment, simultaneously
Chinese prickly ash is crushed, then ginger, Chinese prickly ash, safflower are put into and add 3 times~6 times of decocting to boil 2h~4h extractions, extract solution in cooker
Macroporous resin column is crossed, then with the ethanol gradient elution that concentration is 60%~80%, the Bai Chihua of 1/5 amount of addition after eluent concentration
Seed oil, place into 70 DEG C~85 DEG C of water-bath and heat 1h~3h and stir, be again 80%~90% with volumetric concentration
Alcohol reflux filter 2~4 times, produce the second hybrid filtering liquid, it is standby；
(4) ginkgo leaf, mulberry leaf, cacumen biotae, Eclipta prostrata and lophatherum gracile dried into moisture respectively, be ground into fine powder and mixed equal
After even, 8 times~15 times of its weight are added, the ethanol that concentration is 70%~80%, sealing immersion 5 days~7 days after stirring,
Then refluxing extraction, filtering, recovery filter residue are carried out, obtains the 3rd hybrid filtering liquid, it is standby；
(5) merge the first hybrid filtering liquid, the second hybrid filtering liquid and the 3rd hybrid filtering liquid, then mixed first
Filtrate, the second hybrid filtering liquid and the 3rd hybrid filtering liquid are slowly added to be uniformly mixed in the white pond flower seed oil of 2/5 amount.
Preferably, the step (5) is slow by the first hybrid filtering liquid, the second hybrid filtering liquid and the 3rd hybrid filtering liquid
Add in white pond flower seed oil, stirring 3h~6h is well mixed under conditions of being 30 DEG C~60 DEG C in temperature.
Preferably, the speed stirred under conditions of 30 DEG C~40 DEG C is 80rmp~100rmp, is 45 DEG C~55 in temperature
The speed stirred under conditions of DEG C is 120rmp~150rmp, the speed stirred when temperature is more than 55 DEG C be 160rmp~
180rmp。
The attribute and effect for each herbal raw material that the inventive method uses are as follows：
1st, cloves, Classification system：Syzygium aromaticum, are Myrtaceae, Syzygium.Warm-natured, acrid flavour, it is nontoxic,
With middle benefit gas, warm kidney, the effect of inverse, drops.
2nd, ginger, Classification system：Zingiber officinale Roscoe, are Zingiber, zingiber.Warm-natured, acrid flavour.Have
Inducing sweat and dispelling exogenous evils, warming middle energizer to arrest vomiting, warm lung cough-relieving, solving toxin of fish and crab, the effect of antidote poison.
3rd, Chinese prickly ash, Classification system：Zanthoxylum bungeanum, are Rutaceae, Zanthoxylum.Warm-natured, acrid flavour.Have
The effect of fragrant stomach invigorating, warming spleen and stomach for dispelling cold, damp dispelling and pain relieving, desinsection removing toxic substances, antipruritic solution raw meat.
4th, safflower, Classification system：Carthamus tinctorius L.Warm-natured, acrid flavour, there is invigorate blood circulation, dissolving stasis to stop
The effect of pain.
5th, ginseng, Classification system：Panax ginseng C.A.Mey, are Araliaceae, Panax.Mild-natured, sweet, slight bitter,
Tepor, have and reinforce vital energy, veins takes off admittedly, reinforce the spleen to benefit the lung, promote the production of body fluid to quench thirst, the effect of tranquilize the mind and promote the intelligence.
6th, ganoderma lucidum, Classification system：Ganoderma lucidum, it is Ganodermataceae.Property sweet taste, has invigorating qi for tranquilization, cough-relieving
The effect of relievining asthma, rich in nutrition content are main containing amino acid, polypeptide, protein, fungal lysozyme and carbohydrate, ergosterol, three
Terpene, coumarin glucoside, volatile oil, stearic acid, benzoic acid, alkaloid, vitamin B2 and vitamin C etc., there is section human immunity
The quick lifting of function and the effect of delaying cell aging.
7th, Semen sesami nigrum, Classification system：Semen Sesami Nigrum, are Pedaliaceae, flax category.Property sweet taste, have mend
The effect of liver kidney, benefiting essence-blood, dry ease constipation.Containing substantial amounts of fat and protein, also containing carbohydrate, VitAVitE, ovum
The nutritional ingredients such as phosphatide, calcium, iron, chromium, internal melanin can be increased, be advantageous to natural on-off cycles of hair growth.
9th, the root bark of white mulberry, the root bark of white mulberry are moraceae plants mulberry (Classification system：Morus alba L.) dry root skin, alias mulberry
Root white skin, mulberry root skin, mulberry skin, Bai Sangpi.Bitter in taste, tepor.The effect of energy sedation and analgesia, anti-inflammation, have " hemorrhage gas,
Black beard and hair, happy color ", trichogenous effect.
10th, ginkgo leaf, it is Ginkgoaceae plant Ginkgo biloba Ginkgo biloba L. dried leaf.Ginkgo leaf, astringe the lung, relieving asthma,
It is promoting blood circulation and removing blood stasis, analgesic.Though ginkgo leaf can stimulate circulation, there is very strong removing free radical and antioxidation, ginkgo leaf
In glycosides displayed, amino acid and Amino acid synthesis collagen composition to human body beauty treatment, suppress melanin growth, keep skin light
Pool plays no small effect with elasticity.
11st, the fleece-flower root, Classification system：Fallopia multiflora (Thunb.) Harald, is polygonaceae, fleece-flower root category.
Slightly warm in nature, it is bitter, sweet, puckery, have nourishing the blood and yin, relax bowel, preventing malaria, wind-dispelling, removing toxic substances the effect of.And prepared fleece flower root is what is first
Crow Preparation process product, prepared fleece flower root taste micro-sweet and it is bitter.It is bitter, sweet, puckery, temperature.Return liver, the heart, kidney channel；RADIX POLYGONI MULTIFLORI PREPARATA function tonifying liver
Kidney, benefiting essence-blood, black beard and hair, strengthening the bones and muscles, for blood deficiency chlorosis, dizziness and tinnitus, poliosis, soreness and weakness of waist and knees, extremity numbness, uterine bleeding
Under band, chronic malaria body void etc..
12nd, mulberry leaf, (Mulberry Leaf), scientific name：Folium Mori.Chinese medicine name, it is the dried leaf of moraceae plants mulberry,
It is the conventional food of silkworm, therefore also known as mulberry, thorn mulberry, mulberry fruit tree, yellow wood leaf etc..Mulberry leaf have dispelling wind and heat from the body, clearing away the lungheat and moisturizing, clear liver
The effect of improving eyesight, cooling blood and hemostasis, and have treatment anemopyretic cold, lung-heat type cough, dizziness headache, the dim-sighted effect of hot eyes.The present invention
Do not grown for hair caused by lung heat.
13rd, Radix Angelicae Sinensis, for umbelliferae angelica Angelica sinensis (Oliv.) Diels dry root, Latin
Name：Angelica sinensis.It is warm-natured, sweet, pungent, there is replenishing and activating blood blood-nourishing, menstruction regulating and pain relieving, the effect of relaxing bowel；Energy
Tonifying Qi production of sperm, five viscera settling, strengthen body, beneficial mind, all tangible deficient diseases are omni-benefiting.
14th, cacumen biotae, Classification system：Platycladus orientalis, are Cupressaceae, Platycladus.Cacumen biotae, Chinese medicine
Name, is cupressaceae plant arbor-vitae PLatycladus orientalis (L.) Franco drying branch and leaf, cold in nature, bitter, puckery,
The effect of with cooling blood and hemostasis, black beard and hair, cough-relieving asthma.
15th, Eclipta prostrata, nature and flavor sweet acid, cool blood, hemostasis, kidney tonifying, benefit are cloudy.Haematemesis is controlled, hemoptysis, bleeding from five sense organs or subcutaneous tissue, hematuria, is had blood in stool, blood
Dysentery, knife wound bleeding, poliosis etc., there is the effect of hemostasis, black beard and hair, cough-relieving asthma.《Herbal justice》Think that Eclipta prostrata " enters kidney
Tonifying yin and grow hair." Ming Dynasty name doctor Miao promotees alcohol and Eclipta prostrata is extremely praised highly,《Bencao Jingshu》Middle theory：" bleach it at all times
Grass, when with hereby for victory." he is thought in Chinese herbal medicine, even if the optimal drug Eclipta prostrata of white hair blackening can be made.
16th, lophatherum gracile, (Classification system：Lophatherum gracile) it is grass family, lophatherum gracile category perennial herb is planted
Thing.It is cold in nature, it is sweet, light, can clearing heat and relieving fidgetness, diuresis, cure mainly：In the heart disease heat, cough with dyspnea, haematemesis, heat toxin wind, only quench one's thirst.
Rich in trace elements such as chlorophyll, flavones, phenolic acid compound, amino acid, manganese, zinc in lophatherum gracile.Body can effectively be removed
Interior active oxygen radical, the resisting stress and anti-fatigue ability for strengthening body；Improve memory capability, anti-oxidant, anti-aging work
With, the present invention does not grow for hair caused by lung heat, remove free radical, improve hair it is anti-oxidant, delay resisting for scalp and hair quality
Aging ability.
16th, white pond flower seed oil, white pond flower seed oil contain more than 95% long chain fatty acids with oxidation resistant effect, energy
Shelf-life and the stability of product are effectively increased, is excellent emollient, makes the soft and dry and comfortable skin sense of skin.With other components
Collaboration antioxidation can be played, farthest protects the activity of active ingredient in composition, from oxidation, is effectively enhanced
The toughness and oxidation resistance of composition.
In summary, above-mentioned technical proposal is employed, the beneficial effects of the invention are as follows：
(1) composition of the invention has natural nutritional ingredient, and composition can be prepared into liquid, emulsus or lotion
Shape, the present invention can effectively protect hair quality not injured, make hair difficult for drop-off, by carrying out extraction point to the essential ingredient in Chinese medicine
From can effectively improve the hair care effect of nutritional ingredient in composition.The present invention provides herbal composite each component compatibility and closed
Reason, science, mutually collaboration, there is anti-alopecia-stopping, promote natural on-off cycles of hair growth and reach deep skin tissue through fur, be fur
Tissue provides sufficient nutrient.After composition of the invention being used continuously 15 days, it is possible to reduce the depilation phenomenon of patient, hair quality
With black and gradually a softer and smoother touch trend is turned, after being used continuously 3~6 months, epilation phenomenon is obviously improved, for some
The hair of patient can be grown step by step, and depilation phenomenon does not recur.
(2) arranged in pairs or groups according to present composition ratio, the multiple efficacies composition being rich in is reconciled mutually, cooperateed with, and makes head
Hair and fur can effectively facilitate self-regeneration, promote natural on-off cycles of hair growth, prevention epilation plays prevention well or treatment is made
With, and all raw materials all sources provided by the invention are natural, and it is green, preservative and antibiotic are not added, is not pierced gently
Swash, meet the trend trend of hair products development.
(3) currently preferred composition has good rush penetrating power, can make active ingredient in product faster
Ground reaches deep skin tissue through fur, and the nutrient of abundance can be also provided for fur, enhances metabolism, makes product effect more
It is good.By repetition test, component proportion of the invention can reach maximum product efficacy.
Embodiment
For the objects, technical solutions and advantages of the present invention are more clearly understood, preferred embodiment is enumerated below, to this hair
Bright further description.However, it is necessary to illustrate, many details listed in specification are used for the purpose of making reader to this
The one or more aspects of invention have a thorough explanation, can also realize the present invention's even without these specific details
These aspects.
Embodiment 1
This embodiment offers a kind of herbal composite with hair growth accelerating, the herbal composite is by following heavy
The raw material of amount part is formulated：25 parts of cloves, 9 parts of ginger, 16 parts of Chinese prickly ash, 4 parts of safflower, 18 parts of life, 30 parts of ganoderma lucidum, Semen sesami nigrum
20 parts, 4 parts of the root bark of white mulberry, 12 parts of ginkgo leaf, 28 parts of nine prepared fleece flower root, 8 parts of mulberry leaf, 22 parts of Radix Angelicae Sinensis, 24 parts of cacumen biotae, Eclipta prostrata 8
10 parts of part, 6 parts of lophatherum gracile and white pond flower seed oil.
According to another aspect of the present invention, this embodiment offers a kind of system of the herbal composite with hair growth accelerating
Preparation Method, comprise the following steps：
(1) raw material is taken by following parts by weight respectively：25 parts of cloves, 9 parts of ginger, 16 parts of Chinese prickly ash, 4 parts of safflower, 18 parts of life,
30 parts of ganoderma lucidum, 20 parts of Semen sesami nigrum, 4 parts of the root bark of white mulberry, 12 parts of ginkgo leaf, 28 parts of nine prepared fleece flower root, 8 parts of mulberry leaf, 22 parts of Radix Angelicae Sinensis, arbor-vitae
10 parts of 24 parts of leaf, 8 parts of Eclipta prostrata, 6 parts of lophatherum gracile and white pond flower seed oil；
(2) cloves, life, ganoderma lucidum, the root bark of white mulberry, prepared fleece flower root and Radix Angelicae Sinensis are crushed respectively, then mixed
Particle A is closed, 1h is added water to cook in particle A is mixed, is cooled to after temperature is 35 DEG C and obtains decocting mixture feed liquid A1, then will
Decoct mixture feed liquid A1 to be put into during traditional Chinese medicine extraction fills and add the ethanol that concentration is 70%, sealed under the conditions of being 35 DEG C in temperature
Immersion 48h after carry out heating decoct 1.5h, refilter to obtain filtered fluid A2, into filter residue add 5 times ethanol again through decoct 2h,
Filtered fluid A3 is filtrated to get again, filtered fluid A2 obtained above and filtered fluid A3 is merged, thickening filtration 1 time, is added 2/5 amount
The white pond flower seed oil of (4 parts) is mixed evenly and filtered 1 time, obtains the first hybrid filtering liquid, standby；
(3) ginger, Chinese prickly ash, safflower warm water are cleaned up respectively, ginger is cut into 0.5mm fragment, while by Chinese prickly ash
Crushing, then ginger, Chinese prickly ash, safflower are put into and add 3 times of decocting to boil 2h extractions in cooker, extract solution crosses macroporous resin column, then
With the ethanol gradient elution that concentration is 60%, the white pond flower seed oil of 1/5 amount (2 parts) is added after eluent concentration, places into 70 DEG C
Water-bath in heat and 3h and stir, filtered 4 times with the alcohol reflux that volumetric concentration is 80% again, produce second and mixed
Filtrate is standby；
(4) ginkgo leaf, mulberry leaf, cacumen biotae, Eclipta prostrata and lophatherum gracile dried into moisture respectively, be ground into fine powder and mixed equal
After even, add 8 times of its weight, the ethanol that concentration is 80%, sealing immersion 5 days after stirring, then carry out refluxing extraction,
Filtering, recovery filter residue, obtain the 3rd hybrid filtering liquid, standby；
(5) merge the first hybrid filtering liquid, the second hybrid filtering liquid and the 3rd hybrid filtering liquid, then mixed first
Filtrate, the second hybrid filtering liquid and the 3rd hybrid filtering liquid are slowly added to be stirred in the white pond flower seed oil of 2/5 amount (4 parts)
It is even, wherein, it is to stir 3h under conditions of temperature is 30 DEG C to be uniformly mixed, and the speed of stirring is 100rmp；It is in temperature
2h is stirred under conditions of 45 DEG C, the speed of stirring is 120rmp；1h is stirred when temperature is more than 57 DEG C, the speed of stirring is
160rmp。
Embodiment 2
This embodiment offers a kind of herbal composite with hair growth accelerating, the herbal composite is by following heavy
The raw material of amount part is formulated：15 parts of cloves, 18 parts of ginger, 22 parts of Chinese prickly ash, 9 parts of safflower, 25 parts of life, 38 parts of ganoderma lucidum, black sesame
40 parts of fiber crops, 10 parts of the root bark of white mulberry, 25 parts of ginkgo leaf, 40 parts of nine prepared fleece flower root, 15 parts of mulberry leaf, 33 parts of Radix Angelicae Sinensis, 32 parts of cacumen biotae, non-irrigated lotus
20 parts of 12 parts of grass, 12 parts of lophatherum gracile and white pond flower seed oil.
According to another aspect of the present invention, this embodiment offers a kind of system of the herbal composite with hair growth accelerating
Preparation Method, comprise the following steps：
(1) raw material is taken by following parts by weight respectively：15 parts of cloves, 18 parts of ginger, 22 parts of Chinese prickly ash, 9 parts of safflower, life 25
Part, 38 parts of ganoderma lucidum, 40 parts of Semen sesami nigrum, 10 parts of the root bark of white mulberry, 25 parts of ginkgo leaf, 40 parts of nine prepared fleece flower root, 15 parts of mulberry leaf, Radix Angelicae Sinensis 33
20 parts of part, 32 parts of cacumen biotae, 12 parts of Eclipta prostrata, 12 parts of lophatherum gracile and white pond flower seed oil；
(2) cloves, life, ganoderma lucidum, the root bark of white mulberry, prepared fleece flower root and Radix Angelicae Sinensis are crushed respectively, then mixed
Particle A is closed, 3h is added water to cook in particle A is mixed, is cooled to after temperature is 28 DEG C and obtains decocting mixture feed liquid A1, then will
Decoct mixture feed liquid A1 to be put into during traditional Chinese medicine extraction fills and add the ethanol that concentration is 80%, sealed under the conditions of being 45 DEG C in temperature
Immersion 20h after carry out heating decoct 1h, refilter to obtain filtered fluid A2, into filter residue add 8 times ethanol again through decoct 3h, then
It is secondary to be filtrated to get filtered fluid A3, filtered fluid A2 obtained above and filtered fluid A3 are merged, thickening filtration 3 times, add 2/5 amount (8
Part) white pond flower seed oil be mixed evenly and filter 2 times, obtain the first hybrid filtering liquid, it is standby；
(3) ginger, Chinese prickly ash, safflower warm water are cleaned up respectively, ginger is cut into 1.5mm fragment, while by Chinese prickly ash
Crushing, then ginger, Chinese prickly ash, safflower are put into and add 6 times of decocting to boil 4h extractions in cooker, extract solution crosses macroporous resin column, then
With the ethanol gradient elution that concentration is 80%, the white pond flower seed oil of 1/5 amount (2 parts) is added after eluent concentration, places into 85 DEG C
Water-bath in heat and 1h and stir, filtered 2 times with the alcohol reflux that volumetric concentration is 90% again, produce second and mixed
Filtrate is standby；
(4) ginkgo leaf, mulberry leaf, cacumen biotae, Eclipta prostrata and lophatherum gracile dried into moisture respectively, be ground into fine powder and mixed equal
After even, 15 times of its weight are added, the ethanol that concentration is 70%, sealing immersion 7 days, then carry out backflow and carry after stirring
Take, filter, reclaim filter residue, obtain the 3rd hybrid filtering liquid, it is standby；
(5) merge the first hybrid filtering liquid, the second hybrid filtering liquid and the 3rd hybrid filtering liquid, then mixed first
Filtrate, the second hybrid filtering liquid and the 3rd hybrid filtering liquid are slowly added to be stirred in the white pond flower seed oil of 2/5 amount (4 parts)
It is even, wherein, it is to stir 1.5h under conditions of temperature is 40 DEG C to be uniformly mixed, and the speed of stirring is 100rmp；In temperature
To stir 1h under conditions of 50 DEG C, the speed of stirring is 150rmp；0.5h is stirred when temperature is 60 DEG C, the speed of stirring is
180rmp。
Embodiment 3
This embodiment offers a kind of herbal composite with hair growth accelerating, the herbal composite is by following heavy
The raw material of amount part is formulated：22 parts of cloves, 14 parts of ginger, 20 parts of Chinese prickly ash, 7 parts of safflower, 21 parts of life, 34 parts of ganoderma lucidum, black sesame
32 parts of fiber crops, 8 parts of the root bark of white mulberry, 18 parts of ginkgo leaf, 35 parts of prepared fleece flower root, 12 parts of mulberry leaf, 28 parts of Radix Angelicae Sinensis, 29 parts of cacumen biotae, Eclipta prostrata
15 parts of 10 parts, 9 parts of lophatherum gracile and white pond flower seed oil.
According to another aspect of the present invention, this embodiment offers a kind of system of the herbal composite with hair growth accelerating
Preparation Method, comprise the following steps：
(1) raw material is taken by following parts by weight respectively：22 parts of cloves, 14 parts of ginger, 20 parts of Chinese prickly ash, 7 parts of safflower, life 21
Part, 34 parts of ganoderma lucidum, 32 parts of Semen sesami nigrum, 8 parts of the root bark of white mulberry, 18 parts of ginkgo leaf, 35 parts of prepared fleece flower root, mulberry leaf h12 parts, 28 parts of Radix Angelicae Sinensis,
15 parts of 29 parts of cacumen biotae, 10 parts of Eclipta prostrata, 9 parts of lophatherum gracile and white pond flower seed oil；
(2) cloves, life, ganoderma lucidum, the root bark of white mulberry, prepared fleece flower root and Radix Angelicae Sinensis are crushed respectively, then mixed
Particle A is closed, 2h is added water to cook in particle A is mixed, is cooled to after temperature is 30 DEG C and obtains decocting mixture feed liquid A1, then will
Decoct mixture feed liquid A1 to be put into during traditional Chinese medicine extraction fills and add the ethanol that concentration is 75%, sealed under the conditions of being 40 DEG C in temperature
Immersion 28h after carry out heating decoct 1h, refilter to obtain filtered fluid A2, into filter residue add 7 times ethanol again through decoct 2.5h,
Filtered fluid A3 is filtrated to get again, filtered fluid A2 obtained above and filtered fluid A3 is merged, thickening filtration 2 times, is added 2/5 amount
The white pond flower seed oil of (6 parts) is mixed evenly and filtered 2 times, obtains the first hybrid filtering liquid, standby；
(3) ginger, Chinese prickly ash, safflower warm water are cleaned up respectively, ginger is cut into 1mm fragment, while by zanthoxylum powder
It is broken, then ginger, Chinese prickly ash, safflower are put into and add 5 times of decocting to boil 3h extractions in cooker, extract solution crosses macroporous resin column, then uses
Concentration is 70% ethanol gradient elution, and the white pond flower seed oil of 1/5 amount (3 parts) is added after eluent concentration, places into 75 DEG C
2h is heated in water-bath and is stirred, again with the alcohol reflux filter 23 that volumetric concentration is 85%, produces the second hybrid filtering
Liquid, it is standby；
(4) ginkgo leaf, mulberry leaf, cacumen biotae, Eclipta prostrata and lophatherum gracile dried into moisture respectively, be ground into fine powder and mixed equal
After even, 12 times of its weight are added, the ethanol that concentration is 75%, sealing immersion 7 days, then carry out backflow and carry after stirring
Take, filter, reclaim filter residue, obtain the 3rd hybrid filtering liquid, it is standby；
(5) merge the first hybrid filtering liquid, the second hybrid filtering liquid and the 3rd hybrid filtering liquid, then mixed first
Filtrate, the second hybrid filtering liquid and the 3rd hybrid filtering liquid are slowly added to be stirred in the white pond flower seed oil of 2/5 amount (6 parts)
It is even, wherein, it is to stir 2h under conditions of temperature is 35 DEG C to be uniformly mixed, and the speed of stirring is 90rmp；It is 50 in temperature
1h is stirred under conditions of DEG C, the speed of stirring is 130rmp；1h is stirred in 58 DEG C of temperature, the speed of stirring is 170rmp.
Embodiment 4：Pharmacological toxicity is tested
1. skin irritation test
Take rabbit shaving, contact test induced and excited with present invention combination Chinese herb medicine aqua, at 24 hours and
Viewing test rabbit after 48h, loseing skin has phenomena such as erythema and oedema, with negative control group indifference.As a result show, should
Aqua is bordering on zero to dermoreaction intensity, i.e., without skin allergic reaction.
2. endo-medicine cumulative toxicity test
Test method：From 40 healthy mices, female, male each 20, dose design every 7 days is a phase, each issue of dosage
Respectively 0.10LD50、0.15LD50、0.22LD50、0.34LD50、0.50LD50, the female of this sample, the LD of male mice50
For 5000m parts/k parts BW (five dosage are 500,750,1100,1700,2500m parts/k part BW).Weigh once within every 5 days, adjust
Whole dosage, by the oral gavages of 0.1ml/10 parts BW.After 22 days, animal occurs without death condition, off-test, by ascending-dose
After tested material 15 days, female, buck occur without death condition.
3. acute toxicity test
White mouse oral administration medicine supplying is given with 200 times of this product internal composition clinic consumption per day, is observed 7.As a result all animals
Strong to deposit, its activity, diet, hair, excreta are no abnormal, and hair growth is good and has no obscission, has no that toxicity is anti-
Should.Irritation test is carried out to white mouse damaged skin, there are no irritative response and other adverse reactions.Toxicity test proves,
Said composition no toxic effects and adverse reaction, clinical practice are safe and reliable.
(1) uses patient：Mrs Qin, 42 years old, with slight alopecia seborrheica, scalp itching, hair largely came off (every
Tens of of day), operating pressure is big, and after having used the formula of embodiment 2 to be washed with 7 days, hair no longer comes off, and has soft fine hair on birds or animals
Hair is born, and after 1 month, the place of originally alopecia has grown new hair, and after 3 months, hair is slowly thicker, and hair is all raw
Go out, it is pitch-black moist shinny, after 1 year follow-up do not recur.
(2) uses patient：Poplar, man, 25 years old, often suffer from the symptoms such as cough, insomnia, dreaminess, epilation is serious, head
Send out yellowish, used the formula of embodiment 1 to be washed with 15 days, patient's great rejoicing.It is continuing with 2 months, then without depilation phenomenon, and have
Turn black submissive trend and effect, follow-up 1 year is without recurrence.
(3) uses patient：Huang, man, 55 years old, hair sparse half was white when going to a doctor, and readme has family's hoary hair's medical history, passed through
Implement 3 using the present invention to be washed with 7 months, daily 1~2 time, after 2 months, white hair is graying, and hair starts after 6 months
Growth, after being continuing with 1 year, no depilation phenomenon, turn the trend of black hair by grey hair.
For hair loss patient, after Chinese traditional medicine composition of the present invention 2~4 months, depilation phenomenon significantly reduces.100 alopecias
Patient, alopecia improver 87, unchanged 13, i.e. alopecia effective percentage accounts for 87%, and inefficiency accounts for 13%.Wherein 25~45 years old patient
55, improve 50, non-improver 5；46~55 years old patients 30, improve 27, do not improve 3；56~65 years old patients 10
Example, improve 7, do not improve 3；66~76 years old patients 5, improve 3, do not improve 2.For improver, 5~6 are continuing with
After individual month, the depilation phenomenon of the patient of less than 55 years old is improved, therefore except still having a small number of gerontal patients due to individual former
Because be difficult to outside improving i.e. all be obtained for effectively prevention and improvement, used by long-term experiment, cure rate can up to 90% with
On, and it is uneasy to recur.To in hair loss patient caused by various situations, for example, alopecia areata, medical history Zhong You family morbidity history persons 28, essence
The patient such as refreshing anxiety, the neurasthenia symptom that occurs together, anaemia, 1~2 year by long-term use, cure rate can be up to more than 70%, and is not easy
Recurrence.
Described above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art
For member, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications also should
It is considered as protection scope of the present invention.
Claims (5)
- A kind of 1. herbal composite with hair growth accelerating, it is characterised in that：The herbal composite is by following parts by weight Raw material be formulated：15~25 parts of cloves, 9~18 parts of ginger, 16~22 parts of Chinese prickly ash, 4~9 parts of safflower, 18~25 parts of life, 30~38 parts of ganoderma lucidum, 20~40 parts of Semen sesami nigrum, 4~10 parts of the root bark of white mulberry, 12~25 parts of ginkgo leaf, 28~40 parts of nine prepared fleece flower root, 8~15 parts of mulberry leaf, 22~33 parts of Radix Angelicae Sinensis, 24~32 parts of cacumen biotae, 8~12 parts of Eclipta prostrata, 6~12 parts of lophatherum gracile and white pond flower seed 10~20 parts of oil.
- A kind of 2. herbal composite with hair growth accelerating according to claim 1, it is characterised in that：The Chinese herbal medicine Composition is formulated by the raw material of following parts by weight：22 parts of cloves, 14 parts of ginger, 20 parts of Chinese prickly ash, 7 parts of safflower, 21 parts of life, 34 parts of ganoderma lucidum, 32 parts of Semen sesami nigrum, 8 parts of the root bark of white mulberry, 18 parts of ginkgo leaf, 35 parts of prepared fleece flower root, 12 parts of mulberry leaf, 28 parts of Radix Angelicae Sinensis, arbor-vitae 15 parts of 29 parts of leaf, 10 parts of Eclipta prostrata, 9 parts of lophatherum gracile and white pond flower seed oil.
- A kind of 3. preparation method of the herbal composite with hair growth accelerating, it is characterised in that：Comprise the following steps：(1) raw material is taken by following parts by weight respectively：Cloves, ginger, Chinese prickly ash, safflower, life, ganoderma lucidum, Semen sesami nigrum, the root bark of white mulberry, silver Apricot leaf, prepared fleece flower root, mulberry leaf, Radix Angelicae Sinensis, cacumen biotae, Eclipta prostrata, lophatherum gracile and Bai Chi flower seed oils；(2) cloves, life, ganoderma lucidum, the root bark of white mulberry, prepared fleece flower root and Radix Angelicae Sinensis are crushed respectively, be then well mixed obtain mixing it is broken Expect A, 1h~3h added water to cook in particle A is mixed, be cooled to after temperature is 28 DEG C~35 DEG C and obtain decocting mixture feed liquid A1, Then mixture feed liquid A1 will be decocted to be put into during traditional Chinese medicine extraction fills and add the ethanol that concentration is 70%~80%, be 35 in temperature DEG C~45 DEG C under the conditions of sealing immersion 20h~48h after carry out heating decoct 1h~1.5h, refilter to obtain filtered fluid A2, to filter The ethanol that 5 times~8 times are added in slag is filtrated to get filtered fluid A3, by filtered fluid obtained above again again through decocting 2h~3h A2 and filtered fluid A3 merging, thickening filtration 1 time~3 times, the white pond flower seed oil for adding 2/5 amount is mixed evenly and filtered 1 time ~2 times, the first hybrid filtering liquid is obtained, it is standby；(3) ginger, Chinese prickly ash, safflower warm water are cleaned up respectively, ginger is cut into 0.5mm~1.5mm fragment, while will flower Green pepper is crushed, then ginger, Chinese prickly ash, safflower are put into and add 3 times~6 times of decocting to boil 2h~4h extractions in cooker, and extract solution is excessive Hole resin column, then with the ethanol gradient elution that concentration is 60%~80%, the Bai Chihua seeds of 1/5 amount of addition after eluent concentration Oil, place into 70 DEG C~85 DEG C of water-bath and heat 1h~3h and stir, be again 80%~90% with volumetric concentration Alcohol reflux filters 2 times~4 times, produces the second hybrid filtering liquid, standby；(4) ginkgo leaf, mulberry leaf, cacumen biotae, Eclipta prostrata and lophatherum gracile dried into moisture respectively, be ground into fine powder and be well mixed Afterwards, 8 times~15 times of its weight are added, the ethanol that concentration is 70%~80%, sealing immersion 5 days~7 days after stirring, so Refluxing extraction, filtering, recovery filter residue are carried out afterwards, obtain the 3rd hybrid filtering liquid, it is standby；(5) the first hybrid filtering liquid, the second hybrid filtering liquid and the 3rd hybrid filtering liquid are merged, then by the first hybrid filtering Liquid, the second hybrid filtering liquid and the 3rd hybrid filtering liquid are slowly added to be uniformly mixed in the white pond flower seed oil of 2/5 amount.
- A kind of 4. preparation method of herbal composite with hair growth accelerating according to claim 3, it is characterised in that： First hybrid filtering liquid, the second hybrid filtering liquid and the 3rd hybrid filtering liquid are slowly added to white pond flower seed oil by the step (5) In, stirring 3h~6h is well mixed under conditions of being 30 DEG C~60 DEG C in temperature.
- A kind of 5. preparation method of herbal composite with hair growth accelerating according to claim 4, it is characterised in that： The speed stirred under conditions of 30 DEG C~40 DEG C is 80rmp~100rmp, is stirred under conditions of being 45 DEG C~55 DEG C in temperature Speed be 120rmp~150rmp, the speed stirred when temperature is more than 55 DEG C is 160rmp~180rmp.
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108815084A (en) * | 2018-08-24 | 2018-11-16 | 国珍健康科技（北京）有限公司 | A kind of dandruff control shampoo containing and preparation method thereof containing Herba Lophatheri extract |
| CN109125700A (en) * | 2018-10-25 | 2019-01-04 | 陈培 | A kind of head nursing Chinese medicine preparation and preparation method and care method using it |
| CN110101637A (en) * | 2019-06-03 | 2019-08-09 | 黔南民族医学高等专科学校 | A kind of book on Chinese herbal medicine shampoo and preparation method thereof |
| CN111297772A (en) * | 2019-12-24 | 2020-06-19 | 广西美洛氏化妆品有限公司 | Ganoderma lucidum Chinese herbal medicine anti-hair loss and hair growth liquid and preparation method thereof |
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| CN101049494A (en) * | 2007-04-12 | 2007-10-10 | 谭胜 | Composition of medicine for treating alopecia and preparation method |
| CN102430103A (en) * | 2011-12-09 | 2012-05-02 | 代泽兰 | Medical composite for stopping alopecia and promoting hair growth |
| CN105997836A (en) * | 2016-05-13 | 2016-10-12 | 江燕馨 | Ferment liquid shampoo and preparation method thereof |
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|---|---|---|---|---|
| CN101049494A (en) * | 2007-04-12 | 2007-10-10 | 谭胜 | Composition of medicine for treating alopecia and preparation method |
| CN102430103A (en) * | 2011-12-09 | 2012-05-02 | 代泽兰 | Medical composite for stopping alopecia and promoting hair growth |
| CN105997836A (en) * | 2016-05-13 | 2016-10-12 | 江燕馨 | Ferment liquid shampoo and preparation method thereof |
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| CN108815084A (en) * | 2018-08-24 | 2018-11-16 | 国珍健康科技（北京）有限公司 | A kind of dandruff control shampoo containing and preparation method thereof containing Herba Lophatheri extract |
| CN109125700A (en) * | 2018-10-25 | 2019-01-04 | 陈培 | A kind of head nursing Chinese medicine preparation and preparation method and care method using it |
| CN110101637A (en) * | 2019-06-03 | 2019-08-09 | 黔南民族医学高等专科学校 | A kind of book on Chinese herbal medicine shampoo and preparation method thereof |
| CN111297772A (en) * | 2019-12-24 | 2020-06-19 | 广西美洛氏化妆品有限公司 | Ganoderma lucidum Chinese herbal medicine anti-hair loss and hair growth liquid and preparation method thereof |
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