CN107412709B - Chinese herbal medicine composition with alopecia stopping and hair growth effects and preparation method thereof - Google Patents

Chinese herbal medicine composition with alopecia stopping and hair growth effects and preparation method thereof Download PDF

Info

Publication number
CN107412709B
CN107412709B CN201710739781.XA CN201710739781A CN107412709B CN 107412709 B CN107412709 B CN 107412709B CN 201710739781 A CN201710739781 A CN 201710739781A CN 107412709 B CN107412709 B CN 107412709B
Authority
CN
China
Prior art keywords
parts
filtrate
chinese herbal
herbal medicine
medicine composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201710739781.XA
Other languages
Chinese (zh)
Other versions
CN107412709A (en
Inventor
黄伟文
杨天云
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Guangxi Hegui Group Co ltd
Original Assignee
Guangxi Hegui Group Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guangxi Hegui Group Co ltd filed Critical Guangxi Hegui Group Co ltd
Priority to CN201710739781.XA priority Critical patent/CN107412709B/en
Publication of CN107412709A publication Critical patent/CN107412709A/en
Application granted granted Critical
Publication of CN107412709B publication Critical patent/CN107412709B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06—Fungi, e.g. yeasts
    • A61K36/07—Basidiomycota, e.g. Cryptococcus
    • A61K36/074—Ganoderma
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/14—Cupressaceae (Cypress family), e.g. juniper or cypress
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/758—Zanthoxylum, e.g. pricklyash
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/55—Liquid-liquid separation; Phase separation

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a Chinese herbal medicine composition with the functions of preventing alopecia and promoting hair growth, which is characterized by comprising the following components in part by weight: the Chinese herbal medicine composition is prepared from the following raw materials in parts by weight: 15-25 parts of clove, 9-18 parts of ginger, 16-22 parts of pepper, 4-9 parts of safflower, 18-25 parts of human, 30-38 parts of lucid ganoderma, 20-40 parts of black sesame, 4-10 parts of white mulberry root-bark, 12-25 parts of ginkgo leaf, 28-40 parts of prepared fleece-flower root, 8-15 parts of mulberry leaf, 22-33 parts of angelica, 24-32 parts of cacumen biotae, 8-12 parts of eclipta alba, 6-12 parts of lophatherum gracile and 12-18 parts of chinquapin herb seed oil. The components of the shampoo containing the Chinese herbal medicines provided by the invention are reasonably and scientifically matched and are mutually synergistic, so that the shampoo has the effects of preventing alopecia, promoting hair growth, sterilizing, inhibiting bacteria, diminishing inflammation and relieving itching.

Description

Chinese herbal medicine composition with alopecia stopping and hair growth effects and preparation method thereof
Technical Field
The invention belongs to the technical field of Chinese herbal medicines, and particularly relates to a Chinese herbal medicine composition with the functions of preventing alopecia and promoting hair growth and a preparation method thereof.
Background
The growth condition of the hair is an important embodiment reflecting the physical health condition and image of modern people, and is an important mark of healthy life. Because of the influence of factors such as frequent use of chemical shampoo products, accelerated pace of life, increased working pressure and the like, alopecia has become a common phenomenon of modern people, which troubles many young people and brings much trouble to the daily life of people. Because alopecia affects the personal image and interpersonal relationship, and seriously affects the psychology of the alopecia patient. At present, the medicines for treating alopecia and growing hair on the market are numerous and messy, although scholars carry out a great deal of research on the treatment of alopecia, the existing alopecia-stopping and growing medicine cannot treat both symptoms and root causes, not only is the price high, but also the hair is easy to relapse after stopping the medicine, the effect is not ideal, even scalp and hair are damaged, the hair quality becomes worse, and the like, and the health of people is threatened.
Disclosure of Invention
The invention aims to: aiming at the existing problems, the Chinese herbal medicine composition with the functions of preventing alopecia and growing hair and the preparation method thereof are provided. In order to achieve the purpose of the invention, the technical scheme adopted by the invention is as follows:
according to one aspect of the invention, a Chinese herbal medicine composition with the functions of preventing alopecia and promoting hair growth is provided, and is prepared from the following raw materials in parts by weight: 15-25 parts of clove, 9-18 parts of ginger, 16-22 parts of pepper, 4-9 parts of safflower, 18-25 parts of ginseng, 30-38 parts of lucid ganoderma, 20-40 parts of black sesame, 4-10 parts of white mulberry root-bark, 12-25 parts of ginkgo leaf, 28-40 parts of prepared fleece-flower root, 8-15 parts of mulberry leaf, 22-33 parts of angelica, 24-32 parts of cacumen biotae, 8-12 parts of eclipta alba, 6-12 parts of lophatherum gracile and 10-20 parts of white chingma herb seed oil.
Preferably, the Chinese herbal medicine composition is prepared from the following raw materials in parts by weight: 22 parts of clove, 14 parts of ginger, 20 parts of pepper, 7 parts of safflower, 21 parts of ginseng, 34 parts of ganoderma lucidum, 32 parts of black sesame, 8 parts of white mulberry root-bark, 18 parts of ginkgo leaf, 35 parts of prepared fleece-flower root, 12 parts of mulberry leaf, 28 parts of angelica, 29 parts of cacumen biotae, 10 parts of eclipta alba, 9 parts of lophatherum gracile and 15 parts of meadowrue flower seed oil.
According to another aspect of the present invention, there is provided a method for preparing a herbal composition having alopecia stopping and hair growth effects, comprising the steps of:
(1) respectively taking the following raw materials in parts by weight: flos Caryophylli, rhizoma Zingiberis recens, fructus Zanthoxyli, Carthami flos, Ginseng radix, Ganoderma, semen Sesami Niger, cortex Mori, folium Ginkgo, radix Polygoni Multiflori Preparata, folium Mori, radix Angelicae sinensis, folium Platycladi, Ecliptae herba, folium Bambusae and BAIJIHUAZI oil;
(2) respectively crushing clove, ginseng, ganoderma lucidum, white mulberry root-bark, radix polygoni multiflori preparata and angelica, then uniformly mixing to obtain mixed crushed material A, adding water into the mixed crushed material A for decocting for 1 h-3 h, cooling to 28-35 ℃ to obtain decoction mixture liquid A1, then putting the decoction mixture liquid A1 into a traditional Chinese medicine extraction tank, adding ethanol with the concentration of 70-80%, hermetically soaking for 20 h-48 h at the temperature of 35-45 ℃, heating for decocting for 1 h-1.5 h, filtering to obtain filtrate A2, adding 5-8 times of ethanol into filter residue, decocting for 2 h-3 h, filtering again to obtain filtrate A3, combining the filtrate A2 and the filtrate A3, concentrating and filtering for 1-3 times, adding 2/5 amount of white pool flower seed oil, uniformly mixing and stirring, and filtering for 1-2 times to obtain first mixed filtrate, standby;
(3) respectively cleaning ginger, pepper and safflower with warm water, cutting the ginger into pieces with the size of 0.5-1.5 mm, simultaneously crushing the pepper, putting the ginger, the pepper and the safflower into a cooking pot, adding 3-6 times of water for cooking for 2-4 h for extraction, enabling an extracting solution to pass through a macroporous resin column, performing gradient elution by using 60-80% ethanol, concentrating an eluent, adding 1/5% of white pond flower seed oil, heating in a water bath with the temperature of 70-85 ℃ for 1-3 h, uniformly stirring, performing reflux filtration by using 80-90% ethanol again for 2-4 times to obtain a second mixed filtrate for later use;
(4) drying ginkgo leaves, mulberry leaves, cacumen biotae, eclipta alba and lophatherum gracile, grinding into fine powder, uniformly mixing, adding ethanol with the weight of 8-15 times and the concentration of 70-80%, uniformly stirring, sealing, soaking for 5-7 days, performing reflux extraction, filtering, and recovering filter residues to obtain a third mixed filtrate for later use;
(5) and combining the first mixed filtrate, the second mixed filtrate and the third mixed filtrate, and then slowly adding the first mixed filtrate, the second mixed filtrate and the third mixed filtrate into 2/5 amounts of white pond flower seed oil, stirring and mixing uniformly.
Preferably, in the step (5), the first mixed filtrate, the second mixed filtrate and the third mixed filtrate are slowly added into the white pond flower seed oil, and are stirred for 3 to 6 hours at the temperature of between 30 and 60 ℃ to be uniformly mixed.
Preferably, the stirring speed is 80 to 100rmp at 30 to 40 ℃, 120 to 150rmp at 45 to 55 ℃, and 160 to 180rmp at 55 ℃ or higher.
The method adopts the following Chinese herbal medicine raw materials in terms of properties and effects:
1. clove, Latin scientific name: syzygium aromaticum, a Myrtaceae, Syzygium genus. Warm in nature, pungent in flavor, non-toxic, and has the effects of warming the middle-jiao, warming the kidney, and lowering adverse qi.
2. Fresh ginger, Latin scientific name: zingiber of fisinale Roscoe, Zingiberaceae, Zingiber. Warm in nature and pungent in flavor. Has the effects of sweating, relieving exterior syndrome, warming middle-jiao, relieving vomit, warming lung, relieving cough, and removing toxic materials from fish and crab.
3. Chinese prickly ash, Latin's name: zanthoxylum bungeanum of Rutaceae, genus Zanthoxylum. Warm in nature and pungent in flavor. Has the effects of invigorating stomach, warming spleen and stomach, dispelling cold, eliminating dampness, relieving pain, killing parasites, removing toxic substances, relieving itching, and removing fishy smell.
4. Safflower, Latin scientific name: carthamus tinctorius L. Warm in nature and pungent in flavor, and has the effects of promoting blood circulation, dredging channels, removing blood stasis and relieving pain.
5. Ginseng, the scientific name of latin: panax ginseng C.A.Mey, Araliaceae, Panax. Has mild property, sweet and slightly bitter taste and mild temperature, and has the effects of invigorating primordial qi, recovering pulse, relieving depletion, invigorating spleen, benefiting lung, promoting fluid production, quenching thirst, tranquilizing mind and improving intelligence.
6. Ganoderma lucidum, latin scientific name: ganoderma lucidum. The health-care tea has sweet and mild taste, has the effects of tonifying qi, soothing nerves, relieving cough and asthma, is rich in nutrient components, mainly contains amino acid, polypeptide, protein, fungal lysozyme, saccharide, ergosterol, triterpenes, coumarins, volatile oil, stearic acid, benzoic acid, alkaloid, vitamin B2, vitamin C and the like, and has the effects of quickly improving the human immune function and delaying cell aging.
7. Black sesame, Latin scientific name: semen Sesami Nigrum, a plant of the genus Sesamum of the family Pedaliaceae. Has sweet and mild nature and taste, and has the effects of nourishing liver and kidney, benefiting essence and blood, and moistening intestine dryness. Contains abundant fat and protein, and nutrient components such as saccharide, vitamin A, vitamin E, lecithin, calcium, ferrum, chromium, etc., and can increase melanin in vivo and promote hair growth.
9. Cortex Mori is dry root bark of Morus alba L of Moraceae, and is also called cortex Mori, and cortex Mori. Bitter in property and slightly warm in taste. Has effects of tranquilizing, relieving pain, resisting bacteria and diminishing inflammation, and has effects of bleeding qi, blackening hair and beard, caring skin, and promoting hair growth.
10. Folium Ginkgo is dry leaf of Ginkgo biloba L. Ginkgo leaf, astringes lung, relieves asthma, promotes blood circulation to dissipate blood stasis, and relieves pain. Although ginkgo leaves can promote blood circulation and have strong effects of scavenging free radicals and resisting oxidation, the collagen components synthesized by flavonoid glycoside, amino acid and amino acid in the ginkgo leaves play a small role in beautifying the human body, inhibiting the growth of melanin and keeping the luster and the elasticity of the skin.
11. Polygonum multiflorum, Latin scientific name: fallopia multiflora (Thunb.) Harald, Polygonaceae, genus Polygonum. Has mild warm nature and bitter, sweet and astringent taste, and has the effects of nourishing blood and yin, loosening bowel to relieve constipation, preventing malaria, dispelling pathogenic wind and removing toxic substance. The prepared fleece-flower root is a processed product of the fleece-flower root, and the prepared fleece-flower root has slightly sweet and bitter taste. Bitter, sweet, astringent and warm. It enters liver, heart and kidney meridians; radix Polygoni Multiflori Preparata has effects of nourishing liver and kidney, replenishing essence and blood, blackening hair and beard, and strengthening tendons and bones, and can be used for treating blood deficiency, sallow complexion, giddiness, tinnitus, early white hair, soreness of waist and knees, numbness of limbs, metrorrhagia, leukorrhagia, and asthenia.
12. Mulberry Leaf, (Mulberry Leaf), scientific name: folium Mori. The Chinese medicinal materials are dry leaves of Morus alba L of Moraceae, and are daily food of Bombyx mori L, and are also named as Morus bombycis, Morus baccata, Morus alba L, and Morus alba L. The mulberry leaf has the effects of dispelling wind and heat, clearing lung and moistening dryness, clearing liver and improving eyesight, and cooling blood and stopping bleeding, and has the effects of treating wind and heat type common cold, lung heat and dry cough, dizziness and headache, and conjunctival congestion and dim flower. The invention is used for treating hair growing caused by lung heat.
13. Angelica sinensis, a dried root of Angelica sinensis (Oliv.) Diels, Umbelliferae, Latin scientific name: angelica sinensis. Warm in nature, sweet and pungent in flavor, and has the effects of enriching blood, promoting blood circulation, nourishing blood, regulating menstruation, relieving pain, moistening intestines and relaxing bowels; it can tonify qi, generate essence, calm five internal organs, strengthen physique and benefit spirit, and is not suitable for diseases with physical deficiency.
14. Cacumen biotae, Latin school name: platycladus orientalis, of the genus Platycladus, of the family Cupressaceae. The Chinese medicine name of cacumen Platycladi is dry branch tip and leaf of Franco of family Cupressaceae, such as Chinese arborvitae twig and leaf, and has effects of cold property, bitter and astringent taste, cooling blood and stopping bleeding, blackening beard and hair, and relieving cough and asthma.
15. Eclipta alba, sweet and sour in nature and taste, cools blood, stops bleeding, tonifies kidney and benefits yin. It is used to treat hematemesis, hemoptysis, epistaxis, hematuria, hematochezia, bloody flux, bleeding due to knife wound, premature gray hair, etc., and has the effects of stopping bleeding, blackening hair and beard, and relieving cough and asthma. The herbal Zhengyi states that eclipta alba enters kidney and tonifies yin to grow hair. "Ming Dynasty Miao Zhichun is highly advocated to eclipta prostrata, which is said to be: the ancient and modern whitened herbs are the wins. "he thinks that the best medicine capable of blackening white hair in Chinese herbal medicines is even eclipta alba.
16. Lophatherum gracile (Lophatherum gracile) is a perennial herb of Lophatherum of Gramineae. Cold in nature, sweet and bland in flavor, can clear heat, relieve restlessness and induce diuresis, and is mainly used for treating: chest heat, cough, dyspnea, hematemesis, toxic heat, wind, diabetes, etc. The lophatherum gracile leaves are rich in chlorophyll, flavone, phenolic acid compounds, amino acids, manganese, zinc and other trace elements. Can effectively remove active oxygen free radicals in human body and enhance the anti-stress and anti-fatigue capability of the body; the hair care shampoo has the effects of improving memory capacity, resisting oxidation and delaying aging, and is used for treating hair growth caused by lung heat, removing free radicals, improving the oxidation resistance of hair and delaying the aging capacity of scalp and hair quality.
16. The meadowrue root oil contains more than 95% of long-chain fatty acid with an antioxidant effect, can effectively prolong the shelf life and stability of the product, is an excellent emollient, and enables the skin to feel soft and dry. The antioxidant and other components can play a synergistic antioxidant role, so that the activity of active ingredients in the composition is protected to the maximum extent, the oxidation is avoided, and the viscosity and the antioxidant capacity of the composition are effectively enhanced.
In summary, by adopting the above technical scheme, the beneficial effects of the invention are as follows:
(1) the composition has natural nutrient components, can be prepared into liquid, emulsion or paste, can effectively protect hair from being injured, enables the hair not to fall off easily, and can effectively improve the hair care effect of the nutrient components in the composition by extracting and separating the essential components in the traditional Chinese medicine. The Chinese herbal medicine composition provided by the invention has the advantages of reasonable and scientific compatibility of each component, mutual synergy, hair loss prevention, hair growth promotion, deep skin tissue penetration through fur and sufficient nutrients for the fur tissue. After the composition is continuously used for 15 days, the alopecia phenomenon of patients can be reduced, the hair has the tendency of turning black and gradually softening and smoothing, the hair loss phenomenon is obviously improved after the composition is continuously used for 3-6 months, the hair of some patients can grow gradually, and the alopecia phenomenon does not relapse.
(2) The hair care composition is matched according to the proportion of the composition, and various rich functional components are mutually blended and cooperated, so that the hair and fur can effectively promote self-repair, promote hair growth and prevent hair loss to play a good role in prevention or treatment.
(3) The optimized composition has good penetration promoting capacity, can enable active ingredients in the product to penetrate through fur to reach deep skin tissues more quickly, can provide sufficient nutrients for the fur, promotes metabolism and enables the product effect to be better. Through repeated tests, the component preparation ratio of the invention can achieve the maximum product efficacy.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in further detail below with reference to preferred embodiments. It should be noted, however, that the numerous details set forth in the description are merely for the purpose of providing the reader with a thorough understanding of one or more aspects of the present invention, which may be practiced without these specific details.
Example 1
The embodiment provides a Chinese herbal medicine composition with the functions of preventing alopecia and promoting hair growth, which is prepared from the following raw materials in parts by weight: 25 parts of clove, 9 parts of ginger, 16 parts of pepper, 4 parts of safflower, 18 parts of ginseng, 30 parts of ganoderma lucidum, 20 parts of black sesame, 4 parts of white mulberry root-bark, 12 parts of ginkgo leaf, 28 parts of prepared fleece-flower root, 8 parts of mulberry leaf, 22 parts of angelica, 24 parts of cacumen biotae, 8 parts of eclipta alba, 6 parts of lophatherum gracile and 10 parts of meadowrue seed oil.
According to another aspect of the present invention, there is provided a method for preparing a herbal composition having alopecia stopping and hair growth effects, comprising the steps of:
(1) respectively taking the following raw materials in parts by weight: 25 parts of clove, 9 parts of ginger, 16 parts of pepper, 4 parts of safflower, 18 parts of ginseng, 30 parts of ganoderma lucidum, 20 parts of black sesame, 4 parts of white mulberry root-bark, 12 parts of ginkgo leaf, 28 parts of prepared fleece-flower root, 8 parts of mulberry leaf, 22 parts of angelica, 24 parts of cacumen biotae, 8 parts of eclipta alba, 6 parts of lophatherum gracile and 10 parts of meadowrue root oil;
(2) respectively crushing clove, ginseng, ganoderma lucidum, white mulberry root-bark, radix polygoni multiflori preparata and angelica sinensis, then uniformly mixing to obtain mixed crushed material A, adding water into the mixed crushed material A for decocting for 1 hour, cooling to the temperature of 35 ℃ to obtain decoction mixture liquid A1, then putting the decoction mixture liquid A1 into a traditional Chinese medicine extraction tank, adding 70% ethanol, hermetically soaking at the temperature of 35 ℃ for 48 hours, then heating and decocting for 1.5 hours, then filtering to obtain filtrate A2, adding 5 times of ethanol into filter residue, decocting for 2 hours, filtering again to obtain filtrate A3, combining the obtained filtrate A2 and filtrate A3, concentrating and filtering for 1 time, adding 2/5 (4 parts) of white pond flower seed oil, uniformly mixing and stirring, and filtering for 1 time to obtain first mixed filtrate for later use;
(3) respectively cleaning ginger, pepper and safflower with warm water, cutting the ginger into pieces of 0.5mm, simultaneously crushing the pepper, putting the ginger, the pepper and the safflower into a cooking pot, adding 3 times of water for decocting for 2 hours for extraction, leading an extracting solution to pass through a macroporous resin column, carrying out gradient elution by using 60% ethanol, concentrating an eluent, adding 1/5 (2 parts) of white pool seed oil, putting the white pool seed oil into a water bath at 70 ℃ for heating for 3 hours, uniformly stirring, and carrying out reflux filtration for 4 times by using 80% ethanol in volume concentration to obtain a second mixed filtrate for later use;
(4) drying folium Ginkgo, folium Mori, folium Platycladi, Ecliptae herba and folium Bambusae, grinding into fine powder, mixing, adding 80% ethanol 8 times of the weight of folium Ginkgo, folium Platycladi, Ecliptae herba and folium Bambusae, stirring, sealing, soaking for 5 days, reflux-extracting, filtering, and recovering residue to obtain a third mixed filtrate;
(5) mixing the first mixed filtrate, the second mixed filtrate and the third mixed filtrate, and slowly adding 2/5 (4 parts) of the first mixed filtrate, the second mixed filtrate and the third mixed filtrate into the white pond flower seed oil, and uniformly stirring and mixing, wherein the uniform stirring and mixing is to stir for 3 hours at the temperature of 30 ℃, and the stirring speed is 100 rmp; stirring for 2h at 45 ℃ with a stirring speed of 120 rmp; stirring was carried out at a temperature of 57 ℃ or higher for 1 hour at a stirring speed of 160 rmp.
Example 2
The embodiment provides a Chinese herbal medicine composition with the functions of preventing alopecia and promoting hair growth, which is prepared from the following raw materials in parts by weight: 15 parts of clove, 18 parts of ginger, 22 parts of pepper, 9 parts of safflower, 25 parts of ginseng, 38 parts of ganoderma lucidum, 40 parts of black sesame, 10 parts of white mulberry root-bark, 25 parts of ginkgo leaf, 40 parts of prepared fleece-flower root, 15 parts of mulberry leaf, 33 parts of angelica, 32 parts of cacumen biotae, 12 parts of eclipta alba, 12 parts of lophatherum gracile and 20 parts of meadowrue seed oil.
According to another aspect of the present invention, there is provided a method for preparing a herbal composition having alopecia stopping and hair growth effects, comprising the steps of:
(1) respectively taking the following raw materials in parts by weight: 15 parts of clove, 18 parts of ginger, 22 parts of pepper, 9 parts of safflower, 25 parts of ginseng, 38 parts of ganoderma lucidum, 40 parts of black sesame, 10 parts of white mulberry root-bark, 25 parts of ginkgo leaf, 40 parts of prepared fleece-flower root, 15 parts of mulberry leaf, 33 parts of angelica, 32 parts of cacumen biotae, 12 parts of eclipta alba, 12 parts of lophatherum gracile and 20 parts of meadowrue root oil;
(2) respectively crushing clove, ginseng, ganoderma lucidum, white mulberry root-bark, radix polygoni multiflori preparata and angelica sinensis, then uniformly mixing to obtain mixed crushed material A, adding water into the mixed crushed material A for decocting for 3 hours, cooling to 28 ℃ to obtain decoction mixture liquid A1, then putting the decoction mixture liquid A1 into a traditional Chinese medicine extraction tank, adding 80% ethanol, hermetically soaking at 45 ℃ for 20 hours, heating and decocting for 1 hour, filtering to obtain filtrate A2, adding 8 times of ethanol into filter residue, decocting for 3 hours, filtering again to obtain filtrate A3, combining the obtained filtrate A2 and filtrate A3, concentrating and filtering for 3 times, adding 2/5 (8 parts) of white pool flower seed oil, uniformly mixing and stirring, and filtering for 2 times to obtain first mixed filtrate for later use;
(3) respectively cleaning ginger, pepper and safflower with warm water, cutting the ginger into 1.5mm fragments, simultaneously crushing the pepper, putting the ginger, the pepper and the safflower into a cooking tank, adding 6 times of water for cooking for 4 hours for extraction, passing an extracting solution through a macroporous resin column, performing gradient elution by using 80% ethanol, concentrating an eluent, adding 1/5 parts (2 parts) of white pool flower seed oil, heating in 85 ℃ water bath for 1 hour, uniformly stirring, performing reflux filtration by using 90% ethanol for 2 times again, and obtaining a second mixed filtrate for later use;
(4) drying folium Ginkgo, folium Mori, folium Platycladi, Ecliptae herba and folium Bambusae, grinding into fine powder, mixing, adding ethanol 15 times the weight of folium Ginkgo, folium Platycladi, Ecliptae herba and folium Bambusae, stirring, sealing, soaking for 7 days, reflux-extracting, filtering, and recovering residue to obtain a third mixed filtrate;
(5) mixing the first mixed filtrate, the second mixed filtrate and the third mixed filtrate, and slowly adding 2/5 (4 parts) of the first mixed filtrate, the second mixed filtrate and the third mixed filtrate into the white pond flower seed oil, and uniformly stirring and mixing, wherein the uniform stirring and mixing is to stir for 1.5 hours at the temperature of 40 ℃, and the stirring speed is 100 rmp; stirring for 1h at the temperature of 50 ℃ and the stirring speed of 150 rmp; stirring is carried out at a temperature of 60 ℃ for 0.5h at a stirring speed of 180 rmp.
Example 3
The embodiment provides a Chinese herbal medicine composition with the functions of preventing alopecia and promoting hair growth, which is prepared from the following raw materials in parts by weight: 22 parts of clove, 14 parts of ginger, 20 parts of pepper, 7 parts of safflower, 21 parts of ginseng, 34 parts of ganoderma lucidum, 32 parts of black sesame, 8 parts of white mulberry root-bark, 18 parts of ginkgo leaf, 35 parts of prepared fleece-flower root, 12 parts of mulberry leaf, 28 parts of angelica, 29 parts of cacumen biotae, 10 parts of eclipta alba, 9 parts of lophatherum gracile and 15 parts of meadowrue flower seed oil.
According to another aspect of the present invention, there is provided a method for preparing a herbal composition having alopecia stopping and hair growth effects, comprising the steps of:
(1) respectively taking the following raw materials in parts by weight: 22 parts of clove, 14 parts of ginger, 20 parts of pepper, 7 parts of safflower, 21 parts of ginseng, 34 parts of ganoderma lucidum, 32 parts of black sesame, 8 parts of white mulberry root-bark, 18 parts of ginkgo leaf, 35 parts of prepared fleece-flower root, 12 parts of mulberry leaf h, 28 parts of angelica, 29 parts of cacumen biotae, 10 parts of eclipta alba, 9 parts of lophatherum gracile and 15 parts of meadowrue root oil;
(2) respectively crushing clove, ginseng, ganoderma lucidum, white mulberry root-bark, radix polygoni multiflori preparata and angelica sinensis, then uniformly mixing to obtain mixed crushed material A, adding water into the mixed crushed material A for decocting for 2 hours, cooling to the temperature of 30 ℃ to obtain decoction mixture liquid A1, then putting the decoction mixture liquid A1 into a traditional Chinese medicine extraction tank, adding 75% ethanol, hermetically soaking for 28 hours at the temperature of 40 ℃, heating and decocting for 1 hour, then filtering to obtain filtrate A2, adding 7 times of ethanol into filter residue, decocting for 2.5 hours, filtering again to obtain filtrate A3, combining the obtained filtrate A2 and filtrate A3, concentrating and filtering for 2 times, adding 2/5 (6 parts) of white pond flower seed oil, uniformly mixing and stirring, and filtering for 2 times to obtain first mixed filtrate for later use;
(3) respectively cleaning ginger, pepper and safflower with warm water, cutting the ginger into pieces with the size of 1mm, simultaneously crushing the pepper, putting the ginger, the pepper and the safflower into a cooking pot, adding 5 times of water for cooking for 3 hours for extraction, passing an extracting solution through a macroporous resin column, performing gradient elution by using ethanol with the concentration of 70%, concentrating an eluent, adding 1/5 parts (3 parts) of white pool flower seed oil, heating in a water bath at the temperature of 75 ℃ for 2 hours, uniformly stirring, performing reflux filtration by using the ethanol with the volume concentration of 85% for 3 times to obtain a second mixed filtrate for later use;
(4) drying folium Ginkgo, folium Mori, folium Platycladi, Ecliptae herba and folium Bambusae, grinding into fine powder, mixing, adding 75% ethanol 12 times of the weight of folium Ginkgo, folium Platycladi, Ecliptae herba and folium Bambusae, stirring, sealing, soaking for 7 days, reflux-extracting, filtering, and recovering residue to obtain a third mixed filtrate;
(5) mixing the first mixed filtrate, the second mixed filtrate and the third mixed filtrate, and slowly adding 2/5 (6 parts) of the first mixed filtrate, the second mixed filtrate and the third mixed filtrate into the white pond flower seed oil, and uniformly stirring and mixing, wherein the uniform stirring and mixing is to stir for 2 hours at the temperature of 35 ℃ and the stirring speed is 90 rmp; stirring for 1h at 50 ℃ with a stirring speed of 130 rmp; stirring was carried out at a temperature of 58 ℃ for 1h at a stirring rate of 170 rmp.
Example 4: pharmacological toxicity test
1. Skin irritation test
The rabbits are shaved, induction and excitation contact tests are carried out by using the combined Chinese herbal medicine aqueous solution, and the rabbits are observed and tested after 24 hours and 48 hours, without the phenomena of erythema, edema and the like on the skin, and the differences with a negative control group are avoided. The result shows that the strength of the skin reaction of the water aqua is close to zero, namely, no skin allergy is caused.
2. Cumulative toxicity test of orally administered drug
The test method comprises the following steps: selecting 40 healthy mice, 20 mice each for male and female, wherein the dosage is designed to be one period every 7 days, and the dosage is 0.10LD respectively in each period50、0.15LD50、0.22LD50、0.34LD50、0.50LD50LD of female and male mice of this sample50All are 5000m parts/k parts BW (five doses are 500, 750, 1100, 1700, 2500m parts/k parts BW). The weight of the composition is weighed once every 5 days, the dosage is adjusted, and the composition is orally gavaged according to the ratio of 0.1ml/10 parts BW. After 22 days, no mortality occurred in the animals, and at the end of the test, no mortality occurred in both female and male animals 15 days after increasing doses of the test substance.
3. Acute toxicity test
The oral administration amount of the oral composition is 200 times of the clinical daily dosage, and the oral composition is orally administered to white mice for 7 days. As a result, all animals were kept healthy, no abnormality was found in their activities, diet, hair and excreta, hair growth was good and no shedding phenomenon was observed, and no toxic reaction was observed. The irritation test is carried out on the damaged skin of the white rat, and no irritation reaction and other adverse reactions are seen. Toxicity tests prove that the composition has no toxic effect and adverse reaction, and is safe and reliable in clinical application.
(1) Using the patient: the mousing woman is 42 years old, suffers from slight seborrheic alopecia, the scalp is itchy, the hair falls off in a large amount (tens of hairs every day), the working pressure is high, after 7 days of washing by using the formula of the embodiment 2, the hair does not fall off any more, and vellus hair grows out, after 1 month, new hair grows out from the original hair-losing place, after 3 months, the hair slowly becomes thick, the hair all grows out, the hair is dark, glossy and shiny, and the hair is not relapsed after 1 year follow-up visit.
(2) Using the patient: yang Shi, male, 25 years old, often suffered from symptoms such as cough, insomnia, dreaminess, severe hair loss, pale yellow hair, and the patient enjoyed a great preference for 15 days when washed with the formulation of example 1. After the hair-loss-preventing and hair-loss-preventing tea is continuously used for 2 months, the hair-loss phenomenon does not occur, the hair-loss-preventing and hair-loss-preventing tea has the tendency of turning black and smooth and the effect, and the hair-loss does not relapse after 1 year of follow-up visit.
(3) Using the patient: the hair is thin and half white when people are in treatment for 55 years old and male, the disease history of family white hair is described, the hair is washed for 7 months by using the hair-washing agent 3 of the invention, 1-2 times a day, the white hair turns grey after 2 months of use, the hair starts to grow after 6 months of use, and the hair-losing phenomenon does not occur after 1 year of continuous use, and the trend of turning grey hair into black hair is realized.
For patients with alopecia, after the traditional Chinese medicine composition is used for 2-4 months, the alopecia phenomenon is obviously reduced. The effective rate of the alopecia accounts for 87% and the ineffective rate accounts for 13% in 13 cases of 100 cases of alopecia patients and alopecia improvement patients. 55 patients of 25-45 years old are improved by 50 patients, and 5 patients are not improved; 30 patients aged 46-55 years are improved by 27 cases and not improved by 3 cases; 10 patients of 56-65 years old are improved by 7 cases and not improved by 3 cases; the patients of 66-76 years old had 5 cases of improvement, 3 cases of improvement and 2 cases of no improvement. For the improved patients, after the hair loss phenomenon of the patients under 55 years old is improved after the hair loss prevention and treatment device is continuously used for 5-6 months, all the patients except a few old patients who are difficult to improve due to individual reasons are effectively prevented and improved, and after long-term experiment use, the cure rate can reach over 90 percent and relapse is not easy to occur. After long-term use for 1-2 years, the cure rate of alopecia patients caused by various conditions, such as 28 patients with alopecia areata and family hair in medical history, patients with mental stress, accompanying neurasthenia symptoms, anemia and the like can reach more than 70%, and the alopecia patients are not easy to relapse.
The foregoing is only a preferred embodiment of the present invention, and it should be noted that those skilled in the art can make various improvements and modifications without departing from the principle of the present invention, and these improvements and modifications should also be construed as the protection scope of the present invention.

Claims (4)

1. A preparation method of a Chinese herbal medicine composition with the functions of preventing alopecia and promoting hair growth is characterized by comprising the following steps: the Chinese herbal medicine composition is prepared from the following raw materials in parts by weight: 15-25 parts of clove, 9-18 parts of ginger, 16-22 parts of pepper, 4-9 parts of safflower, 18-25 parts of ginseng, 30-38 parts of lucid ganoderma, 20-40 parts of black sesame, 4-10 parts of white mulberry root-bark, 12-25 parts of ginkgo leaf, 28-40 parts of nine-prepared fleece-flower root, 8-15 parts of mulberry leaf, 22-33 parts of angelica, 24-32 parts of cacumen biotae, 8-12 parts of eclipta alba, 6-12 parts of lophatherum gracile and 10-20 parts of white chingma herb seed oil;
the preparation method of the Chinese herbal medicine composition is characterized by comprising the following steps: the method comprises the following steps:
(1) respectively taking the following raw materials in parts by weight: flos Caryophylli, rhizoma Zingiberis recens, fructus Zanthoxyli, Carthami flos, Ginseng radix, Ganoderma, semen Sesami Niger, cortex Mori, folium Ginkgo, radix Polygoni Multiflori Preparata, folium Mori, radix Angelicae sinensis, folium Platycladi, Ecliptae herba, folium Bambusae and BAIJIHUAZI oil;
(2) respectively crushing clove, ginseng, ganoderma lucidum, white mulberry root-bark, radix polygoni multiflori preparata and angelica, then uniformly mixing to obtain mixed crushed material A, adding water into the mixed crushed material A for decocting for 1 h-3 h, cooling to 28-35 ℃ to obtain decoction mixture liquid A1, then putting the decoction mixture liquid A1 into a traditional Chinese medicine extraction tank, adding ethanol with the concentration of 70-80%, hermetically soaking for 20 h-48 h at the temperature of 35-45 ℃, heating for decocting for 1 h-1.5 h, filtering to obtain filtrate A2, adding 5-8 times of ethanol into filter residue, decocting for 2 h-3 h, filtering again to obtain filtrate A3, combining the filtrate A2 and the filtrate A3, concentrating and filtering for 1-3 times, adding 2/5 amount of white pool flower seed oil, mixing uniformly, stirring and filtering for 1-2 times to obtain first mixed filtrate, standby;
(3) respectively cleaning ginger, pepper and safflower with warm water, cutting the ginger into pieces with the size of 0.5-1.5 mm, simultaneously crushing the pepper, putting the ginger, the pepper and the safflower into a cooking pot, adding 3-6 times of water for cooking for 2-4 h for extraction, enabling an extracting solution to pass through a macroporous resin column, performing gradient elution by using 60-80% ethanol, concentrating an eluent, adding 1/5% white pond flower seed oil, heating in a water bath with the temperature of 70-85 ℃ for 1-3 h, uniformly stirring, performing reflux filtration for 2-4 times by using 80-90% ethanol again to obtain a second mixed filtrate for later use;
(4) drying ginkgo leaves, mulberry leaves, cacumen biotae, eclipta alba and lophatherum gracile, grinding into fine powder, uniformly mixing, adding ethanol with the weight of 8-15 times and the concentration of 70-80%, uniformly stirring, sealing, soaking for 5-7 days, performing reflux extraction, filtering, and recovering filter residues to obtain a third mixed filtrate for later use;
(5) and combining the first mixed filtrate, the second mixed filtrate and the third mixed filtrate, and then slowly adding the first mixed filtrate, the second mixed filtrate and the third mixed filtrate into 2/5 amounts of white pond flower seed oil, stirring and mixing uniformly.
2. The preparation method of the Chinese herbal medicine composition with the functions of stopping alopecia and promoting hair growth according to claim 1, which is characterized by comprising the following steps of: the Chinese herbal medicine composition is prepared from the following raw materials in parts by weight: 22 parts of clove, 14 parts of ginger, 20 parts of pepper, 7 parts of safflower, 21 parts of ginseng, 34 parts of ganoderma lucidum, 32 parts of black sesame, 8 parts of white mulberry root-bark, 18 parts of ginkgo leaf, 35 parts of prepared fleece-flower root, 12 parts of mulberry leaf, 28 parts of angelica, 29 parts of cacumen biotae, 10 parts of eclipta alba, 9 parts of lophatherum gracile and 15 parts of meadowrue flower seed oil.
3. The preparation method of the Chinese herbal medicine composition with the functions of stopping alopecia and promoting hair growth according to claim 1, which is characterized by comprising the following steps of: and (5) slowly adding the first mixed filtrate, the second mixed filtrate and the third mixed filtrate into the white pond flower seed oil, and stirring for 3-6 h at the temperature of 30-60 ℃ to uniformly mix.
4. The preparation method of the Chinese herbal medicine composition with the functions of stopping alopecia and promoting hair growth, according to claim 3, is characterized in that: the stirring speed is 80 to 100rmp at 30 to 40 ℃, 120 to 150rmp at 45 to 55 ℃, and 160 to 180rmp at 55 ℃ or higher.
CN201710739781.XA 2017-08-25 2017-08-25 Chinese herbal medicine composition with alopecia stopping and hair growth effects and preparation method thereof Active CN107412709B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710739781.XA CN107412709B (en) 2017-08-25 2017-08-25 Chinese herbal medicine composition with alopecia stopping and hair growth effects and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710739781.XA CN107412709B (en) 2017-08-25 2017-08-25 Chinese herbal medicine composition with alopecia stopping and hair growth effects and preparation method thereof

Publications (2)

Publication Number Publication Date
CN107412709A CN107412709A (en) 2017-12-01
CN107412709B true CN107412709B (en) 2020-06-30

Family

ID=60434325

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201710739781.XA Active CN107412709B (en) 2017-08-25 2017-08-25 Chinese herbal medicine composition with alopecia stopping and hair growth effects and preparation method thereof

Country Status (1)

Country Link
CN (1) CN107412709B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108815084A (en) * 2018-08-24 2018-11-16 国珍健康科技（北京）有限公司 A kind of dandruff control shampoo containing and preparation method thereof containing Herba Lophatheri extract
CN109125700A (en) * 2018-10-25 2019-01-04 陈培 A kind of head nursing Chinese medicine preparation and preparation method and care method using it
CN110101637A (en) * 2019-06-03 2019-08-09 黔南民族医学高等专科学校 A kind of book on Chinese herbal medicine shampoo and preparation method thereof
CN111297772A (en) * 2019-12-24 2020-06-19 广西美洛氏化妆品有限公司 Ganoderma lucidum Chinese herbal medicine anti-hair loss and hair growth liquid and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101049494A (en) * 2007-04-12 2007-10-10 谭胜 Composition of medicine for treating alopecia and preparation method
CN102430103A (en) * 2011-12-09 2012-05-02 代泽兰 Medical composite for stopping alopecia and promoting hair growth
CN105997836A (en) * 2016-05-13 2016-10-12 江燕馨 Ferment liquid shampoo and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101049494A (en) * 2007-04-12 2007-10-10 谭胜 Composition of medicine for treating alopecia and preparation method
CN102430103A (en) * 2011-12-09 2012-05-02 代泽兰 Medical composite for stopping alopecia and promoting hair growth
CN105997836A (en) * 2016-05-13 2016-10-12 江燕馨 Ferment liquid shampoo and preparation method thereof

Also Published As

Publication number Publication date
CN107412709A (en) 2017-12-01

Similar Documents

Publication Publication Date Title
US9005595B2 (en) Chinese medicine hair-blackening preparation and formula and preparation method therefor
CN105997836A (en) Ferment liquid shampoo and preparation method thereof
CN107412709B (en) Chinese herbal medicine composition with alopecia stopping and hair growth effects and preparation method thereof
CN103054054B (en) Beautifying pigskin jelly and preparation method thereof
KR101294762B1 (en) Functional soap and manufacturing method of it
US9180087B2 (en) Chinese medicine hair-regrowth preparation and formula and preparation method therefor
CN107536774B (en) Traditional Chinese medicine hair blackening and moistening agent and preparation method thereof
JP5646117B2 (en) Hair growth promoter and production method
KR20090012565A (en) Compositions for preventing hair loss or stimulating hair growth containing natural extract
CN112870333A (en) Composition and preparation for improving alopecia and promoting hair growth of human, and preparation method and application thereof
CN111617197A (en) Traditional Chinese medicine composition for hair growth and hair nourishing, and preparation method and application thereof
CN105363015A (en) Medicine composition for treating alopecia and preparation method of medicine composition
CN105614719A (en) Colla corii asini cake for whitening and removing freckles and preparation method thereof
CN112656930A (en) Traditional Chinese medicine shampoo for growing and blackening hair and preparation method thereof
KR101709918B1 (en) Production method and hair restorer including herbal pharmaceutical extracts
CN112294708A (en) Weakly acidic hair washing and protecting active lotion
CN111481621A (en) Traditional Chinese medicine composition for turning white hair into black hair and extraction process
CN105410716A (en) Pork tripe medicinal diet for whitening skin and removing spots and preparation method thereof
CN105614718A (en) Hair blackening, beauty maintaining and young keeping medicinal food applicable to diabetes patients and preparation method of medicinal food
CN113768803B (en) Composition of anti-hair loss and anti-dandruff spray and preparation method thereof
CN106177192B (en) Bi-component compound medicine for treating head oil and dandruff and preparation method thereof
CN108355038A (en) The Chinese medicine bathing instant granular of improvement qi deficiency to blood stasis rheumatism and preparation and application method
KR101715076B1 (en) method of manufacturing and Functional shampoo a main material for A.gramineus
CN102764416B (en) Formula and preparation method of hair blackening preparation
CN112076268A (en) Traditional Chinese medicine lotion for preventing and treating alopecia and blackening hair, preparation method and application

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant