CN105363015A - Medicine composition for treating alopecia and preparation method of medicine composition - Google Patents

Medicine composition for treating alopecia and preparation method of medicine composition Download PDF

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CN105363015A
CN105363015A CN201510992107.3A CN201510992107A CN105363015A CN 105363015 A CN105363015 A CN 105363015A CN 201510992107 A CN201510992107 A CN 201510992107A CN 105363015 A CN105363015 A CN 105363015A
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parts
radix
ethanol
pharmaceutical composition
fructus
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杨小龙
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Changsha Pengyue Wuyang Information Technology Co Ltd
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Changsha Pengyue Wuyang Information Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/254Acanthopanax or Eleutherococcus
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258Panax (ginseng)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605Morus (mulberry)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
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    • A61K9/00Medicinal preparations characterised by special physical form
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    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
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    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The invention relates to the field of Chinese patent medicines, aims to overcome side effects of pharmaceutical drugs for treating alopecia and achieve better treating effect, and provides a medicine composition for treating alopecia. The medicine composition is characterized by being prepared from the following medicinal raw materials in parts by weight: 20-25 parts of angelica sinensis, 4-8 parts of the fruits of Chinese wolfberry, 15-20 parts of dried rehamnnia root, 6-10 parts of ginseng, 16-20 parts of black sesame, 20-25 parts of dried roots of polygonum multiflorum, 15-20 parts of red paeony root, 15-20 parts of fresh ginger, 6-10 parts of herba ecliptae, 8-12 parts of mulberry fruits, 8-12 parts of cortex acanthopanacis, 8-12 parts of divaricate saposhnikovia root, 8-12 parts of lonicera japonica, 8-12 parts of fructus forsythia, 8-12 parts of dandelion and 3-7 parts of liquorice. The medicine composition provided by the invention can permeate the cortical layer and be absorbed by cortical cells, thereby improving the nutrition state of hairs, adjusting balance of endocrine of the organism and sex hormone and stimulating generation of melanin of the human body. The medicine composition provided by the invention has a remarkable effect in clinical trials, and people feels generation of new hairs about half a month.

Description

A kind of can the pharmaceutical composition and preparation method thereof of hair growth
Technical field
The present invention relates to technical field of Chinese patent medicine, be specifically related to a kind of can the pharmaceutical composition and preparation method thereof of hair growth.
Background technology
Modern society, due to environmental pollution and life stress, depilation phenomenon is more and more general, due to life and stress excessive, according to investigations, in China white collar class, have the puzzlement that undergo alopecia of more than 20%.Its main cause is, under the effect of stress, human body arrectores pilorum shrinks, hair is upright, vegetative nerve or nervus centralis function get muddled, hair follicle hair papilla changes and malnutrition, thus causes hair growth function inhibitio, and hair enters resting stage and occurs alopecia.At present, to this kind of alopecia, the important measures taked are wiped outward with minoxidil in minoxidil tincture, Finasteroid oral, some employing hair of scalp plantations.
But Drug therapy is all adopt Western medicine, and its side effect is large, also have some trial Chinese medicine come anti-loss and promote natural on-off cycles of hair growth, but effect is all undesirable.
Summary of the invention
For overcoming hair growth side effects of pharmaceutical drugs problem and reach more effective therapeutic effect, the invention provides a kind of can the pharmaceutical composition and preparation method thereof of hair growth.
Of the present inventionly can the pharmaceutical composition of hair growth to be obtained by the medicinal raw material of following weight:
Radix Angelicae Sinensis 20 ~ 25 parts, Fructus Lycii 4 ~ 8 parts, Radix Rehmanniae 15 ~ 20 parts, Radix Ginseng 6 ~ 10 parts, Semen Sesami Nigrum 16 ~ 20 parts, Radix Polygoni Multiflori 20 ~ 25 parts, Radix Paeoniae Rubra 15 ~ 20 parts, 15 ~ 20 parts, Rhizoma Zingiberis Recens, Herba Ecliptae 6 ~ 10 parts, Fructus Mori 8 ~ 12 parts, Cortex Acanthopancis 8 ~ 12 parts, Radix Saposhnikoviae 8 ~ 12 parts, Flos Lonicerae 8 ~ 12 parts, Fructus Forsythiae 8 ~ 12 parts, Herba Taraxaci 8 ~ 12 parts, 3 ~ 7 parts, Radix Glycyrrhizae.
In order to realize the present invention better, the weight of described medicinal raw material is preferred:
Radix Angelicae Sinensis 22 ~ 24 parts, Fructus Lycii 5 ~ 7 parts, Radix Rehmanniae 16 ~ 18 parts, Radix Ginseng 7 ~ 9 parts, Semen Sesami Nigrum 17 ~ 19 parts, Radix Polygoni Multiflori 22 ~ 24 parts, Radix Paeoniae Rubra 16 ~ 18 parts, 16 ~ 18 parts, Rhizoma Zingiberis Recens, Herba Ecliptae 7 ~ 9 parts, Fructus Mori 9 ~ 11 parts, Cortex Acanthopancis 9 ~ 11 parts, Radix Saposhnikoviae 9 ~ 11 parts, Flos Lonicerae 9 ~ 11 parts, Fructus Forsythiae 9 ~ 11 parts, Herba Taraxaci 9 ~ 11 parts, 4 ~ 6 parts, Radix Glycyrrhizae.
Another preferred version of the present invention is, the weight of described medicinal raw material: Radix Angelicae Sinensis 23 parts, Fructus Lycii 6 parts, Radix Rehmanniae 17 parts, Radix Ginseng 8 parts, Semen Sesami Nigrum 18 parts, Radix Polygoni Multiflori 23 parts, Radix Paeoniae Rubra 17 parts, 17 parts, Rhizoma Zingiberis Recens, Herba Ecliptae 8 parts, Fructus Mori 10 parts, Cortex Acanthopancis 10 parts, Radix Saposhnikoviae 10 parts, Flos Lonicerae 10 parts, Fructus Forsythiae 10 parts, Herba Taraxaci 10 parts, 5 parts, Radix Glycyrrhizae.
The preparation method of pharmaceutical composition of the present invention, comprises the following steps:
(1) Fructus Lycii, Radix Rehmanniae, Radix Ginseng, Radix Polygoni Multiflori, Radix Paeoniae Rubra, Rhizoma Zingiberis Recens, Herba Ecliptae, Fructus Mori, Cortex Acanthopancis, Radix Saposhnikoviae, Flos Lonicerae, Fructus Forsythiae, Herba Taraxaci, Radix Glycyrrhizae are added 10 ~ 40 times of weight water after pulverizing to decoct, filter, obtain filtrate I for subsequent use;
(2) by Radix Angelicae Sinensis pulverizing volumetric concentration be 70% soak with ethanol 3 ~ 7 days, the consumption of 70% ethanol is 2 ~ 3 times of Radix Angelicae Sinensis quality, is filtered by soak, obtains filtrate II for subsequent use;
(3) Semen Sesami Nigrum is smashed to pieces the soak with ethanol 3 ~ 7 days by volumetric concentration 75%, the consumption of 75% ethanol is 2 ~ 3 times of Semen Sesami Nigrum quality, is filtered by soak, obtains filtrate III for subsequent use;
(4) filtrate I, II and III is merged, then add the ethanol that volumetric concentration is 95%, make the quality final concentration of ethanol in medicinal liquid reach 70% ~ 80%.
Another preferred version is: decocting in described step (1) is the soak by water at every turn adding 30 times of quality.
Another preferred version is, in described step (4), the quality final concentration of ethanol is 75%.
Decoction of the present invention is the decocting method of field of Chinese medicines routine, adds water by after pulverizing medicinal materials, and then intense fire is heated to boiling, and after boiling, slow fire boils 10 ~ 20 minutes.
Using method during medicine composite for curing alopecia of the present invention is: dip medicine of the present invention with cotton balls, wiping alopecia place repeatedly, and every day respectively once, one month is a course for the treatment of sooner or later.
The present invention's Radix Rehmanniae used derives from the dry root of scrophulariaceae rehmannia glutinosa plant, and Radix Rehmanniae is the dry product of fresh goods, can Yin-nourishing and body fluid promoting, controls all diseases of Yin and fluid deficiency.Radix Rehmanniae clearing up internal heat by using drugs of bitter in taste and cold in nature, Gan Hanzhi moistens yin nourishing, has effect of clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, intestine moistening.
Radix Polygoni Multiflori is the dried root of polygonum multiflorum thunb PolygonummultiflorumThunb., slightly warm in nature, sweet in the mouth, puckery, and return liver, kidney channel, have enrich and benefit essence and blood, nourishing the liver is calmed the nerves, bone and muscle strengthening, reinforce the kidney crow must function.
Radix Paeoniae Rubra: English redpaeonyroot by name, is the root of dicotyledon medicine ranunculaceae plant Radix Paeoniae (wild species), Paeonia obovata Maxim., river Radix Paeoniae Rubra etc., has clots absorbing, pain relieving, removing heat from blood, detumescence.
Rhizoma Zingiberis Recens is the fresh rhizome of Zingiberaceae herbaceos perennial Rhizoma Zingiberis Recens, and Rhizoma Zingiberis Recens is killed trichomonas vaginitis in vitro and suppressed dermatophytes effect.
Herba Ecliptae: English HerbaEcluptae by name is the dry aerial parts of feverfew Eclipta prostrata EcliptaprostrataL., sweet in the mouth, acid are cold, return kidney, Liver Channel, have nourishing the liver and kidney, effect of cooling blood for hemostasis.
Radix Saposhnikoviae: English DivaricateSaposhnikoviaRoot by name, has expelling pathogenic wind from the body surface; Removing dampness to relieve pain; Spasmolytic; Antipruritic effect.But in formula of the present invention, compatibe drug can be made after adding to produce hair growth promoting effect, obviously promote the growth of the new hair in bald place.
The present invention compared with prior art, has the following advantages:
(1) pharmaceutical composition of the present invention take ethanol as solvent, and ethanol is stronger lytic agent, has volatilization, and its property benefaction, and blood, can relax, permeate cortex, and the ethanol of 75% can kill the fungus on scalp, the function also have detumescence, taking out stains;
(2) the necessary aminoacid of multiple human body and trace element is contained in pharmaceutical composition of the present invention, cortex can be permeated directly by cortical cell is absorbed, strengthen hair follicle nutrition supply, improve the nutritional status of hair, promote scalp blood circulation and drug absorption;
(3) also contain the hormone promoting cell division and growth in pharmaceutical composition of the present invention, hair follicle can be promoted to recover rapidly and arrector pilli muscle formation, promote sebum metabolism, regulate organism endocrine and gonadal hormone to balance, stimulate the generation of human body melanin;
(4) pharmaceutical composition of the present invention effectively can activate rest cell, and make the vigor of skin follicle be able to obvious improvement, skin thickness obviously thickens, thus can the growth of chafe and the growth of hair;
(5) pharmaceutical composition of the present invention effect highly significant in clinical experiment, just can stop obvious alopecia in three days, and the time about two weeks just can feel the generation of new hair, within one month, has just felt the hair of pricking the hand.
Detailed description of the invention
Below enumerate some preferred embodiments of the present invention, to help understanding the present invention further, but scope of the present invention is not limited thereto.
Embodiment 1
Radix Angelicae Sinensis 23 parts, Fructus Lycii 6 parts, Radix Rehmanniae 17 parts, Radix Ginseng 8 parts, Semen Sesami Nigrum 18 parts, Radix Polygoni Multiflori 23 parts, Radix Paeoniae Rubra 17 parts, 17 parts, Rhizoma Zingiberis Recens, Herba Ecliptae 8 parts, Fructus Mori 10 parts, Cortex Acanthopancis 10 parts, Radix Saposhnikoviae 10 parts is got, Flos Lonicerae 10 parts, Fructus Forsythiae 10 parts, Herba Taraxaci 10 parts, 5 parts, Radix Glycyrrhizae by mass parts.
(1) Fructus Lycii, Radix Rehmanniae, Radix Ginseng, Radix Polygoni Multiflori, Radix Paeoniae Rubra, Rhizoma Zingiberis Recens, Herba Ecliptae, Fructus Mori, Cortex Acanthopancis, Radix Saposhnikoviae, Flos Lonicerae, Fructus Forsythiae, Herba Taraxaci, Radix Glycyrrhizae are added 30 times of weight water at every turn after pulverizing to decoct, decoct 2 times, filter, it is for subsequent use that merging filtrate obtains filtrate I;
(2) add the soak with ethanol 5 days that volumetric concentration is 70% after being pulverized by Radix Angelicae Sinensis, the addition of 70% ethanol is 2.5 times of Radix Angelicae Sinensis weight, filters, obtains filtrate II for subsequent use;
(3) ethanol (addition of 75% ethanol is 2.5 times of Semen Sesami Nigrum weight) smashed to pieces by Semen Sesami Nigrum with volumetric concentration is 75% soaks 5 days, filters, obtains filtrate III for subsequent use;
(4) filtrate I, II and III is merged, then add the ethanol that volumetric concentration is 95%, make the quality final concentration of ethanol in medicinal liquid be 75% namely obtain pharmaceutical composition of the present invention.
Embodiment 2
Radix Angelicae Sinensis 22 parts, Fructus Lycii 5 parts, Radix Rehmanniae 1 part, Radix Ginseng 7 parts, Semen Sesami Nigrum 17 parts, Radix Polygoni Multiflori 22 parts, Radix Paeoniae Rubra 18 parts, 16 parts, Rhizoma Zingiberis Recens, Herba Ecliptae 7 parts, Fructus Mori 9 parts, Cortex Acanthopancis 9 parts, Radix Saposhnikoviae 9 parts, Flos Lonicerae 9 parts, Fructus Forsythiae 9 parts, Herba Taraxaci 11 parts, 6 parts, Radix Glycyrrhizae is got by mass parts.
(1) Fructus Lycii, Radix Rehmanniae, Radix Ginseng, Radix Polygoni Multiflori, Radix Paeoniae Rubra, Rhizoma Zingiberis Recens, Herba Ecliptae, Fructus Mori, Cortex Acanthopancis, Radix Saposhnikoviae, Flos Lonicerae, Fructus Forsythiae, Herba Taraxaci, Radix Glycyrrhizae are added 30 times of weight water at every turn after pulverizing to decoct, decoct 2 times, filter, it is for subsequent use that merging filtrate obtains filtrate I;
(2) add the soak with ethanol 5 days that volumetric concentration is 70% after being pulverized by Radix Angelicae Sinensis, the addition of 70% ethanol is 2.5 times of Radix Angelicae Sinensis weight, filters, obtains filtrate II for subsequent use;
(3) ethanol (addition of 75% ethanol is 2.5 times of Semen Sesami Nigrum weight) smashed to pieces by Semen Sesami Nigrum with volumetric concentration is 75% soaks 5 days, filters, obtains filtrate III for subsequent use;
(4) filtrate I, II and III is merged, then add the ethanol that volumetric concentration is 95%, make the quality final concentration of ethanol in medicinal liquid be 75% namely obtain pharmaceutical composition of the present invention.
Embodiment 3
By mass parts get Radix Angelicae Sinensis 24 parts, Fructus Lycii 7 parts, Radix Rehmanniae 18 parts, Radix Ginseng 9 parts, Semen Sesami Nigrum 19 parts, Radix Polygoni Multiflori 24 parts, Radix Paeoniae Rubra 18 parts, 18 parts, Rhizoma Zingiberis Recens, Herba Ecliptae 9 parts, Fructus Mori 11 parts, Cortex Acanthopancis 11 parts, 11 parts, Flos Lonicerae 11 parts, Fructus Forsythiae 11 parts, Herba Taraxaci 9 parts, 4 parts, Radix Glycyrrhizae;
(1) (first intense fire is heated to boiling Fructus Lycii, Radix Rehmanniae, Radix Ginseng, Radix Polygoni Multiflori, Radix Paeoniae Rubra, Rhizoma Zingiberis Recens, Herba Ecliptae, Fructus Mori, Cortex Acanthopancis, Radix Saposhnikoviae, Flos Lonicerae, Fructus Forsythiae, Herba Taraxaci, Radix Glycyrrhizae to be added at every turn 30 times of weight water decoctions after pulverizing, and then slow fire boils 15 minutes), decoct 2 times, filter, it is for subsequent use that merging filtrate obtains filtrate I;
(2) soak 5 days with 70% ethanol (consumption of 70% ethanol is 2 times of Radix Angelicae Sinensis quality) after Radix Angelicae Sinensis being pulverized, soak is filtered, obtains filtrate II for subsequent use;
(3) Semen Sesami Nigrum is smashed to pieces with 75% ethanol (consumption is 2 times of Semen Sesami Nigrum quality) immersion 5 days, soak is filtered, obtains filtrate III for subsequent use;
(4) filtrate I, II and III is merged, then add volumetric concentration 95% ethanol, make the quality final concentration of ethanol in medicinal liquid be 75% namely obtain pharmaceutical composition of the present invention.
Embodiment 4
Application examples: with the pharmaceutical composition prepared by embodiment 1 to 30 hair loss patients (wherein male 25, women 5, the range of age is 20 ~ 50 years old, alopecia degree is from micro-bald to almost alopecia totalis) treat, administrated method is for putting the painting of this medicinal liquid on the skin affected part with cotton swab, every day, sooner or later respectively once each painting put 0.5 ~ 5 minute on the skin, within one month, is a course for the treatment of.After three days, 3 alopecia severe patients have obviously stopped alopecia, and medication is after 15 days, alopecia place of 24 patients has obvious hair growth, and other 1 patient also has obvious hair growth in second course for the treatment of, after three courses for the treatment of, hands touches former alopecia place of patient, and hair grows substantially together.And after medication the health of patient affected part without any difference.Illustrate that the treatment of pharmaceutical composition of the present invention to alopecia is effective and be free from side effects.

Claims (7)

1. can the pharmaceutical composition of hair growth, it is characterized in that, obtained by the medicinal raw material of following weight:
Radix Angelicae Sinensis 20 ~ 25 parts, Fructus Lycii 4 ~ 8 parts, Radix Rehmanniae 15 ~ 20 parts, Radix Ginseng 6 ~ 10 parts, Semen Sesami Nigrum 16 ~ 20 parts, Radix Polygoni Multiflori 20 ~ 25 parts, Radix Paeoniae Rubra 15 ~ 20 parts, 15 ~ 20 parts, Rhizoma Zingiberis Recens, Herba Ecliptae 6 ~ 10 parts, Fructus Mori 8 ~ 12 parts, Cortex Acanthopancis 8 ~ 12 parts, Radix Saposhnikoviae 8 ~ 12 parts, Flos Lonicerae 8 ~ 12 parts, Fructus Forsythiae 8 ~ 12 parts, Herba Taraxaci 8 ~ 12 parts, 3 ~ 7 parts, Radix Glycyrrhizae.
2. according to claim 1 can the pharmaceutical composition of hair growth, it is characterized in that, obtained by the medicinal raw material of following weight:
Radix Angelicae Sinensis 22 ~ 24 parts, Fructus Lycii 5 ~ 7 parts, Radix Rehmanniae 16 ~ 18 parts, Radix Ginseng 7 ~ 9 parts, Semen Sesami Nigrum 17 ~ 19 parts, Radix Polygoni Multiflori 22 ~ 24 parts, Radix Paeoniae Rubra 16 ~ 18 parts, 16 ~ 18 parts, Rhizoma Zingiberis Recens, Herba Ecliptae 7 ~ 9 parts, Fructus Mori 9 ~ 11 parts, Cortex Acanthopancis 9 ~ 11 parts, Radix Saposhnikoviae 9 ~ 11 parts, Flos Lonicerae 9 ~ 11 parts, Fructus Forsythiae 9 ~ 11 parts, Herba Taraxaci 9 ~ 11 parts, 4 ~ 6 parts, Radix Glycyrrhizae.
3. according to claim 1 can the pharmaceutical composition of hair growth, it is characterized in that, obtained by the medicinal raw material of following weight: Radix Angelicae Sinensis 23 parts, Fructus Lycii 6 parts, Radix Rehmanniae 17 parts, Radix Ginseng 8 parts, Semen Sesami Nigrum 18 parts, Radix Polygoni Multiflori 23 parts, Radix Paeoniae Rubra 17 parts, 17 parts, Rhizoma Zingiberis Recens, Herba Ecliptae 8 parts, Fructus Mori 10 parts, Cortex Acanthopancis 10 parts, Radix Saposhnikoviae 10 parts, Flos Lonicerae 10 parts, Fructus Forsythiae 10 parts, Herba Taraxaci 10 parts, 5 parts, Radix Glycyrrhizae.
4. can the preparation method of pharmaceutical composition of hair growth described in claim 1-3 any one claim, it is characterized in that, comprise the following steps:
(1) Fructus Lycii, Radix Rehmanniae, Radix Ginseng, Radix Polygoni Multiflori, Radix Paeoniae Rubra, Rhizoma Zingiberis Recens, Herba Ecliptae, Fructus Mori, Cortex Acanthopancis, Radix Saposhnikoviae, Flos Lonicerae, Fructus Forsythiae, Herba Taraxaci, Radix Glycyrrhizae are added 10 ~ 40 times of weight water after pulverizing to decoct, filter, obtain filtrate I for subsequent use;
(2) by Radix Angelicae Sinensis pulverizing volumetric concentration be 70% soak with ethanol 3 ~ 7 days, the consumption of 70% ethanol is 2 ~ 3 times of Radix Angelicae Sinensis quality, is filtered by soak, obtains filtrate II for subsequent use;
(3) Semen Sesami Nigrum is smashed to pieces the soak with ethanol 3 ~ 7 days by volumetric concentration 75%, the consumption of 75% ethanol is 2 ~ 3 times of Semen Sesami Nigrum quality, is filtered by soak, obtains filtrate III for subsequent use;
(4) filtrate I, II and III is merged, then add the ethanol that volumetric concentration is 95%, make the quality final concentration of ethanol in medicinal liquid reach 70% ~ 80%.
5. according to claim 4 can the preparation method of pharmaceutical composition of hair growth, it is characterized in that, decocting in described step (1) is the soak by water at every turn adding 20 ~ 35 times of quality.
6. according to claim 4 can the preparation method of pharmaceutical composition of hair growth, it is characterized in that, decocting in described step (1) is the soak by water at every turn adding 30 times of quality.
7. according to claim 4 can the preparation method of pharmaceutical composition of hair growth, it is characterized in that, in described step (4), the quality final concentration of ethanol is 75%.
CN201510992107.3A 2015-12-24 2015-12-24 Medicine composition for treating alopecia and preparation method of medicine composition Pending CN105363015A (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105853990A (en) * 2016-06-21 2016-08-17 南安市鸿博计算机技术有限公司 Pharmaceutical composition capable of treating alopecia and preparation method thereof
CN105853595A (en) * 2016-06-21 2016-08-17 南安市鸿博计算机技术有限公司 Medicinal composition for preventing alopecia and preparation method thereof
CN105920563A (en) * 2016-06-21 2016-09-07 南安市鸿博计算机技术有限公司 Pharmaceutical composition capable of promoting hair growth and preparation method thereof
CN106074861A (en) * 2016-08-25 2016-11-09 陈伊芸 A kind of Chinese medicine composition for hair growth
CN115212145A (en) * 2022-07-22 2022-10-21 广东北工商绿色护肤品研究院有限公司 Plant composition with anti-dropping effect and preparation method and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101049494A (en) * 2007-04-12 2007-10-10 谭胜 Composition of medicine for treating alopecia and preparation method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101049494A (en) * 2007-04-12 2007-10-10 谭胜 Composition of medicine for treating alopecia and preparation method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王雨等: "崔玉治疗脱发经验", 《河南中医》 *

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105853990A (en) * 2016-06-21 2016-08-17 南安市鸿博计算机技术有限公司 Pharmaceutical composition capable of treating alopecia and preparation method thereof
CN105853595A (en) * 2016-06-21 2016-08-17 南安市鸿博计算机技术有限公司 Medicinal composition for preventing alopecia and preparation method thereof
CN105920563A (en) * 2016-06-21 2016-09-07 南安市鸿博计算机技术有限公司 Pharmaceutical composition capable of promoting hair growth and preparation method thereof
CN106074861A (en) * 2016-08-25 2016-11-09 陈伊芸 A kind of Chinese medicine composition for hair growth
CN115212145A (en) * 2022-07-22 2022-10-21 广东北工商绿色护肤品研究院有限公司 Plant composition with anti-dropping effect and preparation method and application thereof

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Application publication date: 20160302