CN105853990A - Pharmaceutical composition capable of treating alopecia and preparation method thereof - Google Patents

Pharmaceutical composition capable of treating alopecia and preparation method thereof Download PDF

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CN105853990A
CN105853990A CN201610452077.1A CN201610452077A CN105853990A CN 105853990 A CN105853990 A CN 105853990A CN 201610452077 A CN201610452077 A CN 201610452077A CN 105853990 A CN105853990 A CN 105853990A
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parts
radix
pharmaceutical composition
ethanol
fructus
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张跃霖
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Nanan Hongbo Computer Technology Co Ltd
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Nanan Hongbo Computer Technology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/254—Acanthopanax or Eleutherococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/483—Gleditsia (locust)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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Abstract

The invention relates to the field of Chinese patent medicines and aims at overcoming the problem of side effects of alopecia treating drugs and realizing a better treatment effect. The invention provides a pharmaceutical composition capable of treating alopecia, which comprises the following components: 18-25 parts of angelica sinensis, 4-8 parts of fructus lycii, 15-20 parts of radix rehmanniae, 16-20 parts of black sesame, 12-18 parts of polygonum multiflorum, 12-18 parts of radix paeoniae rubra, 15-20 parts of ginger, 6-10 parts of garden balsam stem, 8-12 parts of mulberry fruit, 8-12 parts of cortex acanthopanacis and 8-12 parts of Chinese honeylocust fruit. The pharmaceutical composition provided by the invention can permeate the cortex to be directly absorbed by the cortex cells, improves the nutrition state of hair, regulates the internal secretion and sex hormone balance of organisms and stimulates the melanogenesis of the human body. The pharmaceutical composition provided by the invention realizes a remarkable effect in clinical experiments; and the patients can feel the generation of new hair after one month and thorny hair after three months.

Description

A kind of can the pharmaceutical composition and preparation method thereof of hair growth
Technical field
The present invention relates to technical field of Chinese patent medicine, be specifically related to a kind of can the pharmaceutical composition and preparation method thereof of hair growth.
Background technology
At present, owing to operating pressure is big, rhythm of life is fast, and alopecia becomes a big problem of puzzlement young people, according to investigations, In China white collar class, there is the puzzlement that undergo alopecia of more than 20%.Main cause is under the effect of stress, people Body arrectores pilorum shrinks, hair is upright, and vegetative nerve or nervus centralis function get muddled, and hair follicle hair papilla changes and nutrition Bad, thus cause hair growth function inhibitio, hair enters resting stage and alopecia occurs.At present alopecia is mainly used minot Wipe outside your tincture of ground, the method for Finasteroid oral, but both drug side effectes are big, also have some to prevent by trial Chinese medicine Alopecia and promotion natural on-off cycles of hair growth, but effect is the most undesirable.
Summary of the invention
For overcoming hair growth side effects of pharmaceutical drugs problem and reaching more effective therapeutic effect, it is de-that the present invention provides one to treat Pharmaceutical composition sent out and preparation method thereof.
The pharmaceutical composition of the hair growth of the present invention is prepared by the medicinal raw material of following weight:
Radix Angelicae Sinensis 18～25 parts, Fructus Lycii 4～8 parts, Radix Rehmanniae 15～20 parts, Semen Sesami Nigrum 16～20 parts, Radix Polygoni Multiflori 12～18 Part, Radix Paeoniae Rubra 12～18 parts, Rhizoma Zingiberis Recens 15～20 parts, Herba speranskiae tuberculatae 6～10 parts, Fructus Mori 8～12 parts, Cortex Acanthopancis 8～12 parts, Fructus Gleditsia 8～12 parts.
In order to the present invention is better achieved, the weight of described medicinal raw material is preferred:
Radix Angelicae Sinensis 20～22 parts, Fructus Lycii 5～7 parts, Radix Rehmanniae 16～18 parts, Semen Sesami Nigrum 17～19 parts, Radix Polygoni Multiflori 14～16 Part, Radix Paeoniae Rubra 14～16 parts, Rhizoma Zingiberis Recens 16～19 parts, Herba speranskiae tuberculatae 7～9 parts, Fructus Mori 9～11 parts, Cortex Acanthopancis 9～11 parts, Fructus Gleditsia 9～11 parts.
Another preferred version of the present invention is, the weight of described medicinal raw material: Radix Angelicae Sinensis 21 parts, Fructus Lycii 6 parts, the Radix Rehmanniae Yellow 17 parts, Semen Sesami Nigrum 18 parts, Radix Polygoni Multiflori 15 parts, Radix Paeoniae Rubra 15 parts, 17 parts of Rhizoma Zingiberis Recens, Herba speranskiae tuberculatae 8 parts, Fructus Mori 10 parts, Cortex Acanthopancis 10 parts, Fructus Gleditsia 10 parts.
The preparation method of pharmaceutical composition of the present invention, comprises the following steps:
(1) after Fructus Lycii, Radix Rehmanniae, Radix Polygoni Multiflori, Radix Paeoniae Rubra, Rhizoma Zingiberis Recens, Herba speranskiae tuberculatae, Fructus Mori, Cortex Acanthopancis, Fructus Gleditsia being pulverized Add 10～40 times of weight water decoct, filter, obtain filtrate I standby；
(2) by soak with ethanol 3 that Radix Angelicae Sinensis pulverizing volumetric concentration is 70%～7 days, the consumption of 70% ethanol be Radix Angelicae Sinensis quality 2～ 3 times, soak is filtered, obtains filtrate II standby；
(3) being smashed to pieces by Semen Sesami Nigrum with the soak with ethanol 3 of volumetric concentration 75%～7 days, the consumption of 75% ethanol is Semen Sesami Nigrum quality 2～3 times, soak is filtered, obtains filtrate III standby；
(4) filtrate I, II and III is merged, be subsequently adding the ethanol that volumetric concentration is 95%, make the quality of ethanol in medicinal liquid eventually Concentration reaches 70%～80%.
Another preferred version is: decocting in described step (1) is the soak by water every time adding 30 times of quality.
Another preferred version is, in described step (4), and the quality final concentration of 75% of ethanol.
Decoction of the present invention is the decocting method that the field of Chinese medicines is conventional, will add water after pulverizing medicinal materials, and then intense fire is heated to Boiling, after boiling, slow fire boils 10～20 minutes.
Using method during the medicine composite for curing alopecia of the present invention is: dips medicine of the present invention with cotton balls, is wiped repeatedly alopecia Place, every day is the most each once, within one month, is a course for the treatment of.
Radix Rehmanniae used by the present invention derives from the dry root of scrophulariaceae rehmannia glutinosa plant, and Radix Rehmanniae is the dry product of fresh goods, can YIN nourishing Promote the production of body fluid, control all diseases of Yin and fluid deficiency.Radix Rehmanniae clearing up internal heat by using drugs of bitter in taste and cold in nature, sweet cold matter profit yin nourishing, have clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting, intestine moistening it Effect.
Radix Polygoni Multiflori is the dried root of polygonum multiflorum thunb Polygonum multiflorum Thunb., slightly warm in nature, sweet in the mouth, Puckery, to return liver, kidney channel, there is tonification essence and blood, nourishing the liver is calmed the nerves, bone and muscle strengthening, the function of the crow palpus that reinforces the kidney.
Radix Paeoniae Rubra: English entitled red paeony root, for dicotyledon medicine ranunculaceae plant Radix Paeoniae (wild species), Paeonia obovata Maxim., The root of river Radix Paeoniae Rubra etc., has clots absorbing, pain relieving, removing heat from blood, detumescence.
Rhizoma Zingiberis Recens is the fresh rhizome of Zingiberaceae herbaceos perennial Rhizoma Zingiberis Recens, and Rhizoma Zingiberis Recens kills trichomonas vaginitis and suppression dermatophytes in vitro Effect.
The present invention compared with prior art, has the advantage that
(1) pharmaceutical composition of the present invention is with ethanol as solvent, and ethanol is stronger lytic agent, has volatilization, its property benefaction, And blood, can relax, permeate cortex, the ethanol of 75% can kill the fungus on scalp, the function also have detumescence, taking out stains；
(2) containing aminoacid and trace element necessary to multiple human body in pharmaceutical composition of the present invention, it is possible to infiltration cortex is direct Absorbed by cortical cell, strengthened hair follicle nutrition supply, improved the nutritional status of hair, promoted that scalp blood circulation and medicine are inhaled Receive；
(3) possibly together with promoting cell division and the hormone of growth in pharmaceutical composition of the present invention, it is possible to promote hair follicle to recover rapidly and Arrector pilli muscle is formed, and promotes sebum metabolism, regulation organism endocrine and gonadal hormone balance, stimulates human body melanin to generate；
(4) pharmaceutical composition of the present invention can effectively activate rest cell, makes the vigor of skin follicle be obviously improved, and skin is thick Degree substantially thickens such that it is able to stimulate growth and the growth of hair of skin；
(5) pharmaceutical composition of present invention effect highly significant in clinical experiment, the time of one month just can feel virgin wool Send out generation, three months just felt prick the hand hair.
Detailed description of the invention
It is exemplified below some preferred embodiments of the present invention, to help being further appreciated by the present invention, but the scope of the present invention not office
It is limited to this.
Embodiment 1
Radix Angelicae Sinensis 21 parts, Fructus Lycii 6 parts, Radix Rehmanniae 17 parts, Semen Sesami Nigrum 18 parts, Radix Polygoni Multiflori 15 parts, Radix Paeoniae Rubra is taken by mass parts 15 parts, 17 parts of Rhizoma Zingiberis Recens, Herba speranskiae tuberculatae 8 parts, Fructus Mori 10 parts, Cortex Acanthopancis 10 parts, Fructus Gleditsia 10 parts；
(1) after Fructus Lycii, Radix Rehmanniae, Radix Polygoni Multiflori, Radix Paeoniae Rubra, Rhizoma Zingiberis Recens, Herba speranskiae tuberculatae, Fructus Mori, Cortex Acanthopancis, Fructus Gleditsia being pulverized Adding 30 times of weight water to decoct every time, decoct 2 times, filter, it is standby that merging filtrate obtains filtrate I；
(2) adding the soak with ethanol 5 days that volumetric concentration is 70% after being pulverized by Radix Angelicae Sinensis, the addition of 70% ethanol is Radix Angelicae Sinensis weight 2.5 times, filter, obtain filtrate II standby；
(3) Semen Sesami Nigrum is smashed to pieces with ethanol that volumetric concentration is 75% 2.5 times of Semen Sesami Nigrum weight (addition of 75% ethanol be) Soak 5 days, filter, obtain filtrate III standby；
(4) filtrate I, II and III is merged, be subsequently adding the ethanol that volumetric concentration is 95%, make the quality of ethanol in medicinal liquid eventually Concentration is 75% pharmaceutical composition i.e. obtaining the present invention.
Embodiment 2
Radix Angelicae Sinensis 20 parts, Fructus Lycii 5 parts, Radix Rehmanniae 16 parts, Semen Sesami Nigrum 17 parts, Radix Polygoni Multiflori 14 parts, Radix Paeoniae Rubra 14 parts, Rhizoma Zingiberis Recens 16 parts, Herba speranskiae tuberculatae 7 parts, Fructus Mori 9 parts, Cortex Acanthopancis 9 parts, Fructus Gleditsia 9 parts.
(1) after Fructus Lycii, Radix Rehmanniae, Radix Polygoni Multiflori, Radix Paeoniae Rubra, Rhizoma Zingiberis Recens, Herba speranskiae tuberculatae, Fructus Mori, Cortex Acanthopancis, Fructus Gleditsia being pulverized Adding 30 times of weight water to decoct every time, decoct 2 times, filter, it is standby that merging filtrate obtains filtrate I；
(2) adding the soak with ethanol 5 days that volumetric concentration is 70% after being pulverized by Radix Angelicae Sinensis, the addition of 70% ethanol is Radix Angelicae Sinensis weight 2.5 times, filter, obtain filtrate II standby；
(3) Semen Sesami Nigrum is smashed to pieces with ethanol that volumetric concentration is 75% 2.5 times of Semen Sesami Nigrum weight (addition of 75% ethanol be) Soak 5 days, filter, obtain filtrate III standby；
(4) filtrate I, II and III is merged, be subsequently adding the ethanol that volumetric concentration is 95%, make the quality of ethanol in medicinal liquid eventually Concentration is 75% pharmaceutical composition i.e. obtaining the present invention.
Embodiment 3
Radix Angelicae Sinensis 22 parts, Fructus Lycii 7 parts, Radix Rehmanniae 18 parts, Semen Sesami Nigrum 19 parts, Radix Polygoni Multiflori 16 parts, Radix Paeoniae Rubra is taken by mass parts 16 parts, 19 parts of Rhizoma Zingiberis Recens, Herba speranskiae tuberculatae 9 parts, Fructus Mori 11 parts, Cortex Acanthopancis 11 parts, Fructus Gleditsia 11 parts；
(1) after Fructus Lycii, Radix Rehmanniae, Radix Polygoni Multiflori, Radix Paeoniae Rubra, Rhizoma Zingiberis Recens, Herba speranskiae tuberculatae, Fructus Mori, Cortex Acanthopancis, Fructus Gleditsia being pulverized Add 30 times of weight water every time and decoct (first intense fire is heated to boiling, and slow fire boils 15 minutes the most again), decoct 2 times, filter, close And filtrate to obtain filtrate I standby；
(2) soak 5 days with 70% ethanol 2 times of Radix Angelicae Sinensis quality (consumption of 70% ethanol be) after Radix Angelicae Sinensis being pulverized, will immersion Liquid filters, and obtains filtrate II standby；
(3) Semen Sesami Nigrum smashed to pieces soak 5 days with 75% ethanol 2 times of Semen Sesami Nigrum quality (consumption be), soak is filtered, Obtain filtrate III standby；
(4) filtrate I, II and III is merged, be subsequently adding volumetric concentration 95% ethanol, make the quality final concentration of ethanol in medicinal liquid It it is 75% pharmaceutical composition i.e. obtaining the present invention.
Embodiment 4
Application examples: with prepared by embodiment 1 pharmaceutical composition to 20 hair loss patients (wherein male 15, women 5, The range of age is 20～50 years old, and alopecia degree is from micro-bald to almost alopecia totalis) to treat, administrated method is by this medicinal liquid with cotton swab Affected part is put in painting on the skin, and every day is the most each once, is coated with every time and puts on the skin 0.5～5 minute, within one month, is a course for the treatment of.After one course for the treatment of of medication, 19 Obvious hair growth, other 1 patient is had also to have obvious hair growth in two second course for the treatment of at the alopecia of name patient, After three courses for the treatment of, hands is touched at the former alopecia of patient, can feel there is difficult to handle hair growth.And the body of patient after medication Body affected part does not has any difference.Illustrate that the pharmaceutical composition of the present invention is effective to the treatment of alopecia and is free from side effects.

Claims (6)

1. can the pharmaceutical composition of hair growth, it is characterized in that, the medicinal raw material of following weight prepare:
Radix Angelicae Sinensis 18～25 parts, Fructus Lycii 4～8 parts, Radix Rehmanniae 15～20 parts, Semen Sesami Nigrum 16～20 parts, Radix Polygoni Multiflori 12～18 Part, Radix Paeoniae Rubra 12～18 parts, Rhizoma Zingiberis Recens 15～20 parts, Herba speranskiae tuberculatae 6～10 parts, Fructus Mori 8～12 parts, Cortex Acanthopancis 8～12 parts, Fructus Gleditsia 8～12 parts.
The most according to claim 1 can the pharmaceutical composition of hair growth, it is characterized in that, by the medical material of following weight Raw material prepares:
Radix Angelicae Sinensis 20～22 parts, Fructus Lycii 5～7 parts, Radix Rehmanniae 16～18 parts, Semen Sesami Nigrum 17～19 parts, Radix Polygoni Multiflori 14～16 Part, Radix Paeoniae Rubra 14～16 parts, Rhizoma Zingiberis Recens 16～19 parts, Herba speranskiae tuberculatae 7～9 parts, Fructus Mori 9～11 parts, Cortex Acanthopancis 9～11 parts, Fructus Gleditsia 9～11 parts.
The most according to claim 1 can the pharmaceutical composition of hair growth, it is characterized in that, by the medical material of following weight Raw material prepare: Radix Angelicae Sinensis 21 parts, Fructus Lycii 6 parts, Radix Rehmanniae 17 parts, Semen Sesami Nigrum 18 parts, Radix Polygoni Multiflori 15 parts, Radix Paeoniae Rubra 15 parts, 17 parts of Rhizoma Zingiberis Recens, Herba speranskiae tuberculatae 8 parts, Fructus Mori 10 parts, Cortex Acanthopancis 10 parts, Fructus Gleditsia 10 parts.
4. according to described in claim 1-3 any one claim can the preparation method of pharmaceutical composition of hair growth, its Feature is, comprises the following steps:
(1) after Fructus Lycii, Radix Rehmanniae, Radix Polygoni Multiflori, Radix Paeoniae Rubra, Rhizoma Zingiberis Recens, Herba speranskiae tuberculatae, Fructus Mori, Cortex Acanthopancis, Fructus Gleditsia being pulverized Add 10～40 times of weight water decoct, filter, obtain filtrate I standby；
(2) by soak with ethanol 3 that Radix Angelicae Sinensis pulverizing volumetric concentration is 70%～7 days, the consumption of 70% ethanol be Radix Angelicae Sinensis quality 2～ 3 times, soak is filtered, obtains filtrate II standby；
(3) being smashed to pieces by Semen Sesami Nigrum with the soak with ethanol 3 of volumetric concentration 75%～7 days, the consumption of 75% ethanol is Semen Sesami Nigrum quality 2～3 times, soak is filtered, obtains filtrate III standby；
(4) filtrate I, II and III is merged, be subsequently adding the ethanol that volumetric concentration is 95%, make the quality of ethanol in medicinal liquid eventually Concentration reaches 70%～80%.
The most according to claim 4 can the preparation method of pharmaceutical composition of hair growth, it is characterized in that, described step (1) Middle decoction is the soak by water every time adding 30 times of quality.
The most according to claim 4 can the preparation method of pharmaceutical composition of hair growth, it is characterized in that, described step (4) In, the quality final concentration of 75% of ethanol.
CN201610452077.1A 2016-06-21 2016-06-21 Pharmaceutical composition capable of treating alopecia and preparation method thereof Pending CN105853990A (en)

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CN105363015A (en) * 2015-12-24 2016-03-02 长沙鹏跃五洋信息科技有限公司 Medicine composition for treating alopecia and preparation method of medicine composition
CN105477615A (en) * 2015-12-30 2016-04-13 李素萍 Traditional Chinese medicine composition for preventing hair loss and nourishing hair

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CN104208630A (en) * 2014-09-09 2014-12-17 吕铝淼 Alopecia-preventing hair-generating medicine
CN105363015A (en) * 2015-12-24 2016-03-02 长沙鹏跃五洋信息科技有限公司 Medicine composition for treating alopecia and preparation method of medicine composition
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