CN101224271A - Chinese traditional medicine compounds for treating poliosis - Google Patents
Chinese traditional medicine compounds for treating poliosis Download PDFInfo
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- CN101224271A CN101224271A CNA2008100728013A CN200810072801A CN101224271A CN 101224271 A CN101224271 A CN 101224271A CN A2008100728013 A CNA2008100728013 A CN A2008100728013A CN 200810072801 A CN200810072801 A CN 200810072801A CN 101224271 A CN101224271 A CN 101224271A
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Abstract
The invention relates to the traditional Chinese medicine pharmaceutical field, in particular to a traditional Chinese medicine combination for treating poliosis. The combination is an oral preparation which is prepared by fine crushed material or extracted active ingredients and a pharmaceutical excipient; wherein, the weight proportion range of the raw materials used for extracting active ingredients or being processed into the fine crushed material is as follows: 160-240 parts of prepared radix rehmanniae, 80-120 parts of prepared common macrocarpium fruit, 80-120 parts of yam, 60-90 parts of moutan bark, 60-90 parts of tuckahoe, 60-90 parts of alisma orientale and 160-240 parts of prepared polygonum multiflorum. The invention is added with proper amount of polygonum multiflorum on the basis of studying the application of the ancient notable prescription of 'LiuWeiDiHuang pill' so as to strengthen the function of tonifying the liver and the kidney of the traditional 'LiuWeiDiHuang pill' and achieve the efficacy of blackening beard and hair; the invention can achieve the function of treating both symptoms and root cause for poliosis caused by kidney deficiency. .
Description
Technical field
The present invention relates to field of traditional Chinese medicine pharmacy, relate to the Chinese medicine composition that is used for the treatment of poliosis particularly.
Background technology
Along with the adult age constantly increases, because of weak suffering from a deficiency of the kidney given birth to the situation ubiquity of poliosis prematurely, usually people use various hair dyes, hair care agent to cover up the defective of poliosis, but cure the symptoms, not the disease, and fundamentally do not eliminate hair by the black immanent cause that bleaches and send out.
" LIUWEI DIHUANG WAN " is the name side based on nourishing kidney yin, form by Radix Rehmanniae Preparata, Fructus Corni, Rhizoma Dioscoreae, Rhizoma Alismatis, Cortex Moutan, Poria Six-element Chinese medicine, from the composition of prescription, it can reach three cloudy with the effects of mending (tonifying kidney-yin, tonifying liver the moon, tonifying spleen-yin), can tonifying kidney-yin as Radix Rehmanniae Preparata; Fructus Corni then is that Liver and kidney is mended together, reaches the purpose of the kidney invigorating by tonifying liver; Rhizoma Dioscoreae energy tonifying speen and tonifying kidney is mended the day after tomorrow by spleen invigorating.
Radix Polygoni Multiflori is the dried root of polygonum multiflorum thunb.Record at first in Song dynasty " Kaibao Bencao ".Ming Dynasty's Compendium of Material Medica is pointed out Radix Polygoni Multiflori, and the effect of " only pained, replenishing QI and blood, black moustache is sent out, improving healthy complexion, the of a specified duration long muscles and bones of clothes, beneficial marrow, it is not old to prolong life " is arranged." Kaibao Bencao " also has the record of Radix Polygoni Multiflori " clothes make us son for a long time ".Radix Polygoni Multiflori can be divided into fresh jewelry black, Radix Polygoni Multiflori, Radix Polygoni Multiflori Preparata because of the processing method difference.1. fresh jewelry black is without finished, and its intestine moistening, repercussive effect are better; 2. Radix Polygoni Multiflori is through drying in the sun, and effect is longer than resolving heat and reducing pathogenic fire, yin nourishing relieving constipation and the pain that disappears swells; 3. Radix Polygoni Multiflori Preparata have enrich blood, the effect of the kidney invigorating, beneficial essence, black beard and hair, be a kind of strengthening by means of tonics medicine, be applicable to diseases such as geromorphism, early whitening of hair, anemia are weak, deficiency of the kidney seminal emission, soreness of the waist and knees, dizziness and blurred vision.
Modern medicine study proves: Radix Polygoni Multiflori bitter in the mouth, sweet, puckery, warm in nature, its invigorating the liver and kidney effect is remarkable, has the effect of benefiting essence-blood, strengthening bone and muscle, black beard and hair, defying age again, and cold not dry not oiliness, be tonic medicine, Chinese crude drug compatibilities such as normal and Radix Rehmanniae, Fructus Lycii, Semen Cuscutae.
For the effect of the invigorating the liver and kidney of strengthening tradition " LIUWEI DIHUANG WAN ", also reach the effect of people's " black beard and hair ", be necessary lappingout ancient prescription again, reach the purpose of weeding out the old and bring forth the new, to solve the problem of giving birth to poliosis because of suffering from a deficiency of the kidney.
Summary of the invention
Technical problem to be solved by this invention is by overcoming the defective of tradition " LIUWEI DIHUANG WAN ", and according to theory of Chinese medical science and clinical practice, provides a kind of Chinese medicine composition that is used for the treatment of poliosis.
The present invention's technical scheme disclosed and protection is: a kind of Chinese medicine composition that is used for the treatment of poliosis; said composition is by the oral formulations that fine powder minces or the effective ingredient that extracts and pharmaceutic adjuvant are made, wherein effective component extracting or be processed into the weight portion ratio range that fine powder minces raw materials used and be: Radix Rehmanniae Preparata 160-240, Fructus Corni (system) 80-120, Rhizoma Dioscoreae 80-120, Cortex Moutan 60-90, Poria 60-90, Rhizoma Alismatis 60-90, Radix Polygoni Multiflori Preparata 160-240.
As improvement of the technical scheme or preferred, effective component extracting or be processed into the weight portion proportioning that fine powder minces raw materials used and be in this Chinese medicine composition: Radix Rehmanniae Preparata 160, Fructus Corni (system) 80, Rhizoma Dioscoreae 80, Cortex Moutan 60, Poria 60, Rhizoma Alismatis 60, Radix Polygoni Multiflori Preparata 160.
The described oral formulations of above technical scheme includes pill, granule, capsule, tablet or the oral liquid made from existing conventional pharmaceutical technology (tcd).
Pharmaceutic adjuvant of the present invention is the adjuvant various commonly used that is adopted in the conventional formulation.
Wherein, producing of active component can adopt conventional pharmaceutical technology (tcd) to extract, and specifically can adopt: Radix Rehmanniae Preparata, Fructus Corni (system), Rhizoma Dioscoreae, Cortex Moutan, Poria, Rhizoma Alismatis, the Radix Polygoni Multiflori Preparata of getting the said ratio amount.Decoct with water 2-3 time, filter, merging filtrate leaves standstill, and filters, and concentrating under reduced pressure becomes thick extractum, and this extractum is active component extract.
The active component extract of above extraction be can be made into various oral formulations according to a conventional method.
Also can get Chinese crude drug ready by the proportional quantity of Radix Rehmanniae Preparata, Fructus Corni (system), Rhizoma Dioscoreae, Cortex Moutan, Poria, Rhizoma Alismatis, Radix Polygoni Multiflori Preparata, crushed after being dried becomes fine powder, cross 80-120 order dusting cover, get and to get fine powder behind the fine powder dry heat sterilization and mince, add Mel routinely again and can make honeyed pill, adding entry is that binding agent can make the watered pill.
The present invention has following effect:
1, the present invention is in ancient times on the medication basis of name side " LIUWEI DIHUANG WAN ", added an amount of Radix Polygoni Multiflori, not only strengthened the effect of the invigorating the liver and kidney of tradition " LIUWEI DIHUANG WAN ", but also reached the effect of " black beard and hair ", the common poliosis that produces because of suffering from a deficiency of the kidney has been reached the effect for the treatment of both the principal and secondary aspects of a disease.
2, medication of the present invention is simple and clear, scientific and reasonable, has only increased Herba indigoferae Pseudotinctoriae, just makes the patient in the process of nourishing kidney yin, makes hair black by leucismus gradually, makes vast patient obtain the pleasantly surprised of accident.
The clinical drug effect checking of Chinese medicine composition of the present invention:
One, the preparation of test medicine " seven flavor Dihuang Wans ":
Ratio in Radix Rehmanniae Preparata 160, Fructus Corni (system) 80, Rhizoma Dioscoreae 80, Cortex Moutan 60, Poria 60, Rhizoma Alismatis 60, Radix Polygoni Multiflori Preparata 160 is got Chinese crude drug ready, crushed after being dried becomes fine powder, cross 80-120 order dusting cover, get the fine powder dry heat sterilization again, the Mel that adds an amount of (per 100 gram fine powders add 100 to 120 grams) is routinely made the small honey pill of 0.15 gram, its water content＜13% can be adorned 60 grams for every bottle.
Two, instructions of taking:
Every day, each was once oral sooner or later, each 9 gram, i.e. small honey pills of 60.
Three, treatment time:
Take 30 days courses of treatment uninterruptedly.
Four, identifying object:
358 gray hair of the middle aged patients that treat over nearly 3 years.
Five, clinical treatment result:
In 358 patients, wherein, male's 216 examples, women's 142 examples, the mean age is 46 years old.Through taking continuously of 30 days courses of treatment, poliosis mostly has minimizing to some extent, and each patient's body constitution all has improvement in various degree.Wherein, poliosis has 116 people that have that obviously alleviate effect, accounts for 32.4%; 192 people that alleviate are arranged, account for 53.6%; Change unconspicuous 50 people, only account for 14%.Have among the patient and adhere to taking 2-3 the course of treatment, its curative effect is better.To confirming also in most of patient's the return visit that this medical instrument has its unique curative effect, it has broken through traditional " LIUWEI DIHUANG WAN ", is to have to be extensive use of a kind of new drug that is worth.
Six, untoward reaction:
All cases are not found untoward reaction, prove its safety and have no side effect.
Seven, conclusion:
Can draw according to its pharmacology and Clinical Analysis, " seven flavor Dihuang Wans " really has the treatment person in middle and old age give birth to poliosis because of suffering from a deficiency of the kidney effect, can be widely used in clinical.
With Chinese medicine composition of the present invention is " the seven flavor Dihuang Wans " that the basis produces, and based on its significant curative effect in treatment gray hair of the middle aged disease for many years, has been used for the prescription drugs of clinical treatment by the approval of medicine prison department of local autonomous region.
The specific embodiment
The preparation of embodiment 1, extract
Get raw material of Chinese medicine ready in Radix Rehmanniae Preparata 160, Fructus Corni (system) 80, Rhizoma Dioscoreae 80, Cortex Moutan 60, Poria 60, Rhizoma Alismatis 60, Radix Polygoni Multiflori Preparata 160 weight portion ratios, twice of the water boiling and extraction that adds 8 times of amounts, merge and filter, leave standstill, filter, concentrating under reduced pressure becomes extractum, and this extractum is active component extract.
Also can extract active component wherein with the ethanol extraction method of routine.
The preparation of embodiment 2, oral agents
The active component extract that embodiment 1 extracted is equipped with corresponding medicinal adjuvant (dextrin, magnesium stearate etc.) can makes dosage forms such as tablet, granule and capsule with conventional pharmaceutical technology.
Embodiment 3, fine powder mince or the preparation of powder
Get Chinese crude drug ready in Radix Rehmanniae Preparata 160, Fructus Corni (system) 80, Rhizoma Dioscoreae 80, Cortex Moutan 60, Poria 60, Rhizoma Alismatis 60, Radix Polygoni Multiflori Preparata 160 weight portion ratios, crushed after being dried becomes fine powder, cross 80-120 order dusting cover, get again and can get fine powder behind the fine powder dry heat sterilization and mince, directly be powder (can take after mixing it with hot water) after the pack.
The preparation of embodiment 4, small honey pill
Proportion by Radix Rehmanniae Preparata 140-180, Fructus Corni (system) 50-70, Rhizoma Dioscoreae 70-90, Cortex Moutan 50-70, Poria 50-70, Rhizoma Alismatis 50-70, Radix Polygoni Multiflori Preparata 140-180 weight portion is got Chinese crude drug ready, crushed after being dried becomes fine powder, cross 80-120 order dusting cover, get the fine powder dry heat sterilization again, add an amount of Mel routinely and promptly can be made into small honey pill.
The preparation of embodiment 5, the watered pill
Get Chinese crude drug ready in Radix Rehmanniae Preparata 160, Fructus Corni (system) 80, Rhizoma Dioscoreae 80, Cortex Moutan 60, Poria 60, Rhizoma Alismatis 60, Radix Polygoni Multiflori Preparata 160 weight portion ratios, crushed after being dried becomes fine powder, crossing 80-120 order dusting cover, get the fine powder dry heat sterilization again, is that binding agent can make the watered pill with water.
The preparation of embodiment 6, oral liquid
Get first-class medical material ready in Radix Rehmanniae Preparata 240, Fructus Corni (system) 120, Rhizoma Dioscoreae 120, Cortex Moutan 90, Poria 90, Rhizoma Alismatis 90, Radix Polygoni Multiflori Preparata 240 weight portion ratios, adding water decocts three times continuously, filter, merging filtrate, concentrate, add again pharmaceutic adjuvant Mel or or aspartame and diluent water promptly can be made into oral liquid.
Present invention focuses on to provide a kind of to solve the Chinese medicine composition of giving birth to the problem of poliosis because of suffering from a deficiency of the kidney; it focuses on each component and proportioning thereof; can make various oral formulations with existing conventional pharmaceutical processing technology; above embodiment just exemplifies simple embodiment of the present invention; under the situation that does not deviate from the invention spirit and essence thereof; be familiar with all similar variations of making according to the present invention of those of ordinary skill in the art, all should belong to the protection domain that claims of the present invention limit.
Claims (4)
1. Chinese medicine composition that is used for the treatment of poliosis, said composition is by the oral formulations that fine powder minces or the effective ingredient that extracts and pharmaceutic adjuvant are made, wherein effective component extracting or be processed into the weight portion ratio range that fine powder minces raw materials used and be: Radix Rehmanniae Preparata 160-240, Fructus Corni (system) 80-120, Rhizoma Dioscoreae 80-120, Cortex Moutan 60-90, Poria 60-90, Rhizoma Alismatis 60-90, Radix Polygoni Multiflori Preparata 160-240.
2. the Chinese medicine composition that is used for the treatment of poliosis according to claim 1, wherein, effective component extracting or be processed into the weight portion proportioning that fine powder minces raw materials used and be: Radix Rehmanniae Preparata 160, Fructus Corni (system) 80, Rhizoma Dioscoreae 80, Cortex Moutan 60, Poria 60, Rhizoma Alismatis 60, Radix Polygoni Multiflori Preparata 160.
3. the Chinese medicine composition that is used for the treatment of poliosis according to claim 1 and 2, wherein, described oral formulations includes pill, granule, capsule, tablet or the oral liquid made from existing conventional pharmaceutical technology (tcd).
4. the application of Chinese medicine composition in the treatment poliosis that is used for the treatment of poliosis according to claim 1 and 2.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNA2008100728013A CN101224271A (en) | 2008-01-07 | 2008-01-07 | Chinese traditional medicine compounds for treating poliosis |
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| CNA2008100728013A CN101224271A (en) | 2008-01-07 | 2008-01-07 | Chinese traditional medicine compounds for treating poliosis |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102552628A (en) * | 2012-01-09 | 2012-07-11 | 李承平 | Pharmaceutical composition for nourishing yin and tonifying kidney |
| CN106075047A (en) * | 2016-08-05 | 2016-11-09 | 李玲玲 | A kind of Chinese medicinal capsule treating poliosis and preparation method thereof |
| CN107126496A (en) * | 2017-05-16 | 2017-09-05 | 黄平县兴且民族民间中草医药科学发展有限责任公司 | It is a kind of to treat traditional Chinese medicine pill of white hair and preparation method thereof |
| CN110327411A (en) * | 2019-07-31 | 2019-10-15 | 东莞自然衡健康科技有限公司 | Black hair composition |
-
2008
- 2008-01-07 CN CNA2008100728013A patent/CN101224271A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102552628A (en) * | 2012-01-09 | 2012-07-11 | 李承平 | Pharmaceutical composition for nourishing yin and tonifying kidney |
| CN106075047A (en) * | 2016-08-05 | 2016-11-09 | 李玲玲 | A kind of Chinese medicinal capsule treating poliosis and preparation method thereof |
| CN107126496A (en) * | 2017-05-16 | 2017-09-05 | 黄平县兴且民族民间中草医药科学发展有限责任公司 | It is a kind of to treat traditional Chinese medicine pill of white hair and preparation method thereof |
| CN110327411A (en) * | 2019-07-31 | 2019-10-15 | 东莞自然衡健康科技有限公司 | Black hair composition |
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Open date: 20080723 |