CN1134824A - Oral liquid for regulating women's sexual function - Google Patents

Oral liquid for regulating women's sexual function Download PDF

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Publication number
CN1134824A
CN1134824A CN 95104292 CN95104292A CN1134824A CN 1134824 A CN1134824 A CN 1134824A CN 95104292 CN95104292 CN 95104292 CN 95104292 A CN95104292 A CN 95104292A CN 1134824 A CN1134824 A CN 1134824A
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China
Prior art keywords
oral liquid
radix
crude drug
women
gram
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CN 95104292
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Chinese (zh)
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CN1048175C (en
Inventor
杨泽林
梁茂新
杨金庆
李绍华
周巧兰
李东安
刘云锋
李伟
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HONGBAO PHARMACEUTICAL CO Ltd HEBEI PROV
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HONGBAO PHARMACEUTICAL CO Ltd HEBEI PROV
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Priority to CN95104292A priority Critical patent/CN1048175C/en
Publication of CN1134824A publication Critical patent/CN1134824A/en
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Publication of CN1048175C publication Critical patent/CN1048175C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Abstract

The composition of the invented oral liquid consists of prepared rehmannia root, saline cistanche, longspur epimedium, root of herbaceous peony, fruit of Chinese wolfberry, etc. traditional Chinese medicinal herbs. Indications: femal sexual involution, irregular menstruation, aching and limp waist and knee, lassitude and amnesia. Functions shown by pharmacolhogical verification and clinical trial are nourishing the blood, regulating the menstrual function, invigorating and tonifying the liver and kidney, strengthening yin and arresting convulision.

Description

A kind of oral liquid of regulating women's sexual function
The present invention relates to a kind of oral liquid of regulating women's sexual function, belong to health care medicine.
In recent years, along with the research and development of sex medicine, Chinese medicine and pharmacy has had some experiences to understanding and the treatment that women's sexual function goes down, as Li Yuyou to amenorrhea and the indifferent person of libido due to the obesity, control from stagnation of phlegm-damp, the cloudy depressed opinion of spleen, the side adds flavor (cognition of " the new traditional Chinese medical science in Tianjin " 1990,7,17 treatment amenorrheas) with the grey attached expectorant ball of leading, sombre for the women, Wang Wanzu is from the insufficiency of kidney-YANG diagnosis and treatment, with warm palace soup with disease adaptability in tactics (" the Sichuan traditional Chinese medical science " 1992,4.46. temperature palace soup treatment married woman is sombre); Zhang Chaojun then sombrely obtains effect with the treatment of self-control wine of sheep kidney; (treatment of " the Sichuan traditional Chinese medical science " 1995.5.37 wine of sheep kidney is sombre) Zheng Chunlei is to the sombre double bitter taste of seeing of women, costalgia person, examine and be dampness-heat in the liver and gallbladder disease, the side is sombre with Decoction of Gentiana for Purging the Liver-fire treatment) (treatment of " the Sichuan traditional Chinese medical science " 1990.1.42. Decoction of Gentiana for Purging the Liver-fire is sombre) bibliographic reference shows, being used for the treatment of women's sexual function now goes down, the menoxenia companion sees irritability, insomnia, lethargy, forgetful, many symptoms such as depression, the clinical doctor of polyphyly draws up prescription, the patient oneself decocts into decoction and takes, extremely inconvenient, in addition, these clinical reports of testing controlled are not all from the clear and definite side's medicine of experimental viewpoint mechanism of action with the pharmacodynamics data are provided.
The objective of the invention is to release a kind of fixed oral liquid formulation and go down to treat women's sexual function clinically, many symptoms of climacteric syndrome and association as a kind of pure Chinese medicine health-care medicine, guarantee the curative effect and the quality of medicine.
This health care medicine of the present invention is pure Chinese medicinal components, in order to regulate women's sexual function.Dosage form is an oral liquid, and its crude drug is formed and comprised (W/W)
Radix Rehmanniae Preparata 8-12%, Herba Cistanches 6-10%, Herba Epimedii 6-10%, Radix Paeoniae Alba 6-10%, Fructus Ligustri Lucidi 5-8%, Fructus Corni 5-8%, Fructus Lycii 5-8%, Caulis Spatholobi 5-8%, Radix Salviae Miltiorrhizae 3-6%, Radix Dipsaci 4-8%, Semen Ziziphi Spinosae (parched) 4-8%, Radix Angelicae Sinensis 5-8%, Cortex Phellodendri 5-8%, Rhizoma Anemarrhenae 5-8%, Cortex Moutan 3-6% Rhizoma Chuanxiong 2-5%.Oral liquid is the concentrated extract of above crude drug component.
The formulation method of this oral liquid comprises that the crude drug component is added moisture decocts filtration three times, merging filtrate is concentrated into relative density 1.0-1.2, adding 95% ethanol makes pure content reach 70%, fully stir evenly, left standstill 24 hours, filter, reclaim ethanol, add correctives, antiseptic, adding the ratio that entry makes crude drug and oral liquid is 1: 1.
The oral liquid of adjusting women's sexual function of the present invention is earlier with the nourishing blood for regulating menstruation, liver and kidney tonifying is attached most importance to, from the fixing Chinese medicine component Cheng Fang of dosage form, confirm through preclinical pharmacology, this oral liquid can significantly shorten rat incubation period emotionally, improve estradiol content in the teenage female Mus serum, improve the dispirited degree of going to ovum female mice uterus, increase adrenal gland's weight, certain calmness and resisting fatigue are also arranged, oxygen lack resistant function (seeing Appendix 1,2) clinical observation shows that oral liquid of the present invention has nourishing blood for regulating menstruation, the function of liver and kidney tonifying, nourishing YIN for tranquillization.Be applicable to women's deficiency of the liver and kindey, hyposexuality due to vim and vigour are uncomfortable, vaginal dryness, lethargy, have a dizzy spell, disease such as fidgety irritability, insomnia forgetfulness, soreness of the waist and knees, menoxenia, total effective rate is 93%, has the effect of paying of the obvious no any poison of effect (seeing Appendix 3) that improves women's sexual function and 9 sees Appendix 4,5) oral liquid of the present invention is significant to numerous women's psychosomatic health.
Below in conjunction with embodiment, describe technology contents of the present invention in detail.
1. female gentle liquid (trade name) prescription is formed:
The Radix Rehmanniae Preparata 90 gram Herba Cistanches 80 gram Herba Epimedii 80 gram Radix Paeoniae Alba 80 gram Fructus Ligustri Lucidi 60 Keshan Fructus Evodiaes 60 gram Fructus Lycii 60 gram Caulis Spatholobis 60 gram Radix Salviae Miltiorrhizaes 50 gram Radix Dipsacis 40 gram Semen Ziziphi Spinosae (parched)s 40 gram Radix Angelicae Sinensis 60 gram Cortex Phellodendris 80 gram Rhizoma Anemarrhenaes 80 gram Cortex Moutans 50 gram Rhizoma Chuanxiongs 30 gram sodium benzoate 3 gram steviosides are an amount of.
Above crude drug is decocted with water 3 times, add 10 times in water, decoct filtration in 2 hours for the 1st time; Add 8 times in water the 2nd time, decocted 1.5 hours, filter; Add 6 times in water the 3rd time, decocted 1 hour, and filtered, merging filtrate is concentrated into relative density 1.1-1.2, adding 95% ethanol makes and contains alcohol amount and reach 70%, fully stir evenly, leave standstill after 24 hours and filter recovery ethanol, add sodium benzoate, stevioside makes into the 1000ml heated and boiled with water, leaves standstill filtration, and packing promptly.
Embodiment 2, and female gentle liquid (trade name) prescription is formed
The Radix Rehmanniae Preparata 90 gram Herba Cistanches 80 gram Herba Epimedii 80 gram Radix Paeoniae Alba 80 gram Fructus Ligustri Lucidi 60 Keshan Fructus Evodiaes 60 gram Fructus Lycii 60 gram Caulis Spatholobis 60 gram Radix Salviae Miltiorrhizaes 50 gram Radix Dipsacis 40 gram Semen Ziziphi Spinosae (parched)s 40 gram Radix Angelicae Sinensis 60 gram Cortex Phellodendris 80 gram Rhizoma Anemarrhenaes 80 gram Cortex Moutans 50 gram Rhizoma Chuanxiongs 30 gram sodium benzoate 3 gram steviosides are an amount of.
Preparation method is with embodiment 1.

Claims (2)

1. its crude drug composition of oral liquid of regulating women's sexual function comprises (W/W)
Radix Rehmanniae Preparata 8-12%, Herba Cistanches 6-10%, Herba Epimedii 6-10%, Radix Paeoniae Alba 6-10%, Fructus Ligustri Lucidi 5-8%, Fructus Corni 5-8%, Fructus Lycii 5-8%, Caulis Spatholobi 5-8%, Radix Salviae Miltiorrhizae 3-6%, Radix Dipsaci 4-8%, Semen Ziziphi Spinosae (parched) 4-8%, Radix Angelicae Sinensis 5-8%, Cortex Phellodendri 5-8%, Rhizoma Anemarrhenae 5-8%, Cortex Moutan 3-6% Rhizoma Chuanxiong 2-5%.
Its oral liquid is the concentrated extract of above crude drug component.
2. a preparation method of regulating the oral liquid of women's sexual function comprises that the crude drug component is added moisture decocts filtration three times, merging filtrate is concentrated into relative density 1.0-1.2, adding 95% ethanol makes pure content reach 70%, fully stir evenly, left standstill 24 hours, filter, reclaim ethanol, add correctives, antiseptic, adding the ratio that entry makes crude drug and oral liquid is 1: 1.
CN95104292A 1995-05-02 1995-05-02 Oral liquid for regulating women's sexual function Expired - Fee Related CN1048175C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN95104292A CN1048175C (en) 1995-05-02 1995-05-02 Oral liquid for regulating women's sexual function

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN95104292A CN1048175C (en) 1995-05-02 1995-05-02 Oral liquid for regulating women's sexual function

Publications (2)

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CN1134824A true CN1134824A (en) 1996-11-06
CN1048175C CN1048175C (en) 2000-01-12

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CN95104292A Expired - Fee Related CN1048175C (en) 1995-05-02 1995-05-02 Oral liquid for regulating women's sexual function

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Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1314437C (en) * 2005-09-07 2007-05-09 高守坤 Medicine for treating acute and chronic bronchial asthma and cough and its prepn
CN101375971B (en) * 2008-09-27 2011-03-30 曹开镛 Rejuvenating and yang-invigorating formulation for treating yin deficiency type impotence and preparation method thereof
CN101850016B (en) * 2009-03-31 2012-02-22 江苏康缘药业股份有限公司 Chinese medicinal composition for treating premature ovarian failure and preparation method thereof
CN102406838A (en) * 2011-12-06 2012-04-11 赵英霖 Traditional Chinese medicine for treating menopausal syndrome
CN102688372A (en) * 2012-05-21 2012-09-26 何圣 Skin care decoction for improving women sub-health, and preparation method thereof
CN103655966A (en) * 2013-12-23 2014-03-26 青岛安信医疗器械有限公司 Traditional Chinese medicine liquid for treating puerperal irregular menstruation
CN104173726A (en) * 2014-08-28 2014-12-03 圣原健康产业有限公司 Traditional Chinese medicine composition for postpartum recovery and preparation method and application of traditional Chinese medicine composition
CN105169076A (en) * 2013-07-31 2015-12-23 朱保生 Traditional Chinese medicine composition for treating irregular menstruation
CN106728649A (en) * 2017-01-12 2017-05-31 张超英 A kind of health pill for woman climacteric
CN107496875A (en) * 2017-09-19 2017-12-22 袁贯丽 A kind of Chinese medicine of QI invigorating
CN114681561A (en) * 2022-04-24 2022-07-01 康芝药业股份有限公司 Method for purifying active ingredients in Zhenlingdan mixture

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1314437C (en) * 2005-09-07 2007-05-09 高守坤 Medicine for treating acute and chronic bronchial asthma and cough and its prepn
CN101375971B (en) * 2008-09-27 2011-03-30 曹开镛 Rejuvenating and yang-invigorating formulation for treating yin deficiency type impotence and preparation method thereof
CN101850016B (en) * 2009-03-31 2012-02-22 江苏康缘药业股份有限公司 Chinese medicinal composition for treating premature ovarian failure and preparation method thereof
CN102406838B (en) * 2011-12-06 2013-01-09 赵英霖 Traditional Chinese medicine for treating menopausal syndrome
CN102406838A (en) * 2011-12-06 2012-04-11 赵英霖 Traditional Chinese medicine for treating menopausal syndrome
CN102688372B (en) * 2012-05-21 2014-01-29 何圣 Skin care decoction for improving women sub-health, and preparation method thereof
CN102688372A (en) * 2012-05-21 2012-09-26 何圣 Skin care decoction for improving women sub-health, and preparation method thereof
CN105169076A (en) * 2013-07-31 2015-12-23 朱保生 Traditional Chinese medicine composition for treating irregular menstruation
CN103655966A (en) * 2013-12-23 2014-03-26 青岛安信医疗器械有限公司 Traditional Chinese medicine liquid for treating puerperal irregular menstruation
CN104173726A (en) * 2014-08-28 2014-12-03 圣原健康产业有限公司 Traditional Chinese medicine composition for postpartum recovery and preparation method and application of traditional Chinese medicine composition
CN104173726B (en) * 2014-08-28 2017-07-28 圣原健康产业有限公司 Chinese medicine composition for postpartum recuperating and its preparation method and application
CN106728649A (en) * 2017-01-12 2017-05-31 张超英 A kind of health pill for woman climacteric
CN107496875A (en) * 2017-09-19 2017-12-22 袁贯丽 A kind of Chinese medicine of QI invigorating
CN114681561A (en) * 2022-04-24 2022-07-01 康芝药业股份有限公司 Method for purifying active ingredients in Zhenlingdan mixture

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