CN101530479B - Traditional Chinese medicine for treating diabetes mellitus and muscle atrophy - Google Patents

Traditional Chinese medicine for treating diabetes mellitus and muscle atrophy Download PDF

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CN101530479B
CN101530479B CN2008101018420A CN200810101842A CN101530479B CN 101530479 B CN101530479 B CN 101530479B CN 2008101018420 A CN2008101018420 A CN 2008101018420A CN 200810101842 A CN200810101842 A CN 200810101842A CN 101530479 B CN101530479 B CN 101530479B
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chinese medicine
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traditional chinese
muscle atrophy
diabetes mellitus
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CN101530479A (en
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刘新壮
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Rugao Grinding Head Construction Development Co Ltd
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Lvyuan Qiuzheng Technology Development Co Ltd
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Abstract

The invention belongs to the field of traditional Chinese medicines for treating diabetes mellitus and provides a traditional Chinese medicine for treating diabetes mellitus complicated by muscle atrophy, aiming at achieving good efficacy and rapid onset of action. The traditional Chinese medicine is prepared by rhizoma corydalis, suberect spatholobus stem, sanchi, beautiful sweetgum fruit, lucid ganoderma, Chinese angelica, cassia twig, manchurian wildginger, red paeony root and other raw materials and has the effects of banking up root by strengthening vital qi, benefiting qi, nourishing blood, promoting blood circulation for removing blood stasis and relieving pain. The traditional Chinese medicine has good effect and rapid onset of action and is characterized by significant effect, exact efficacy and rapid onset of action.

Description

一种治疗糖尿病并发肌肉萎缩的中药 A traditional Chinese medicine for treating diabetes complicated with muscle atrophy

                           技术领域Technical field

本发明属于治疗糖尿病的中药领域。The invention belongs to the field of traditional Chinese medicine for treating diabetes.

                           背景技术 Background technique

糖尿病患者免疫力低下,发生周围神经病变者比较普遍,其中部分患者并发肌肉萎缩。当前用于治疗糖尿病肌肉萎缩的中药方面,存在一些不足:其一,效果不够明显;其二,见效比较迟缓,患者对此不够满意。Diabetic patients have low immunity, and peripheral neuropathy is more common, and some patients are complicated by muscle atrophy. There are some deficiencies in the traditional Chinese medicine currently used to treat diabetic muscle atrophy: first, the effect is not obvious enough; second, the effect is relatively slow, and patients are not satisfied with it.

针对上述提出的问题,本发明提供一种治疗糖尿病并发肌肉萎缩的中药,它能解决以往此类中药治疗中效果不够明显,见效比较迟缓的问题,效果好,见效快,具有效果显著,药效确切,见效迅速较快的优点。In view of the above-mentioned problems, the present invention provides a Chinese medicine for treating diabetes complicated by muscle atrophy, which can solve the problem that the effect of this kind of traditional Chinese medicine is not obvious enough in the past, and the effect is relatively slow. Definitely, the advantages of quicker and quicker results.

                           发明内容Contents of Invention

本发明是通过以下技术方案来实现的:The present invention is achieved through the following technical solutions:

一种治疗糖尿病并发肌肉萎缩的中药,采用中药原料制备,配方为(按重量比):A kind of Chinese medicine for treating diabetes complicated with muscle atrophy, prepared by adopting Chinese medicine raw materials, the formula is (by weight):

延胡索0.3-2.5份         鸡血藤0.4-3.6份        三七0.3-2.5份Corydalis 0.3-2.5 parts Spatholobus 0.4-3.6 parts Sanqi 0.3-2.5 parts

路路通0.2-1.8份         灵芝0.15-1份           当归0.3-2.5份Passepartout 0.2-1.8 parts Ganoderma lucidum 0.15-1 parts Angelica 0.3-2.5 parts

桂枝0.2-1.8份           细辛0.15-1份           赤芍0.3-2.5份Guizhi 0.2-1.8 parts Asarum 0.15-1 parts Radix Paeoniae Alba 0.3-2.5 parts

这种治疗糖尿病并发肌肉萎缩的中药是由下列方法制成的:This traditional Chinese medicine for treating diabetes complicated with muscle atrophy is made by the following methods:

(1)按上述重量比,将延胡索、鸡血藤、路路通、当归、桂枝、细辛、赤芍经常规水提取工艺提取,制成浸膏细粉;(1) Corydalis Corydalis, Spatholobus Spatholobus, Passepartout, Angelica, Guizhi, Asarum, Radix Paeoniae Rubra are extracted by conventional water extraction process according to the above weight ratio, and made into extract powder;

(2)按上述重量比,将三七、灵芝分别研成细粉,与上述浸膏细粉混合,搅拌均匀;根据需要,可制成中药冲剂、颗粒剂、散剂、胶囊剂、水丸剂、片剂等剂型。(2) According to the above weight ratio, grind Panax notoginseng and Ganoderma lucidum into fine powder respectively, mix with the above-mentioned extract powder, and stir evenly; as required, it can be made into Chinese medicine granules, granules, powders, capsules, water pills, Dosage forms such as tablets.

本发明是根据民间传统配方,根据中医扶正培本、活血化瘀的理论,精心研制而成。中医认为,糖尿病并发肌肉萎缩,属周围神经病变,为虚损严重,气滞血瘀所致,治当扶正培本,益气养血,活血化瘀。方中灵芝益气,扶正培本,大补五脏;当归、鸡血藤活血养血,行血补血;灵芝、当归、鸡血藤相伍补气活血,气旺血足;本方配伍延胡索、赤芍、三七、路路通活血化瘀药物,各有所用,延胡索活血行气而止痛,赤芍清热散瘀而定痛,三七活血止血而定痛,路路通活血祛风,利水通经;佐以细辛镇痛祛痰;桂枝解热抗炎。诸药配伍,相得益彰,共奏扶正培本,益气养血,活血化瘀止痛之功,效果好,见效快,具有效果显著、药效确切、见效较快的优点。The present invention is elaborately developed according to the folk traditional formula and the theory of traditional Chinese medicine of strengthening the body and strengthening the body, promoting blood circulation and removing blood stasis. Traditional Chinese medicine believes that diabetes complicated with muscle atrophy is a peripheral neuropathy, which is caused by severe wasting, qi stagnation and blood stasis. Ganoderma lucidum invigorates qi, strengthens the body, nourishes the five viscera; Angelica, Spathiphyllum promotes blood and nourishes blood, promotes blood and nourishes blood; Ganoderma, Angelica, and Spatholobus combine together to invigorate qi, activate blood, and nourish blood; this prescription is compatible with Corydalis, Radix Paeoniae Rubra, Panax notoginseng, and Passepartout are blood-activating and stasis-removing medicines. To stimulate the meridian; adjuvant with asarum to relieve pain and expectorant; cassia twig antipyretic and anti-inflammatory. All the medicines are compatible and complement each other, and play the functions of strengthening the body, nourishing qi and nourishing blood, promoting blood circulation, removing blood stasis and relieving pain. The effect is good, and the effect is fast.

                         具体实施方式 Detailed ways

通过以下实施方式对本发明做具体说明:The present invention is specifically described by the following embodiments:

1、取以下配方(重量按克为单位)1. Take the following formula (the weight is in grams)

延胡索36克       鸡血藤55克       三七36克Corydalis Corydalis 36 grams Spatholobus Spatholobus 55 grams Sanqi 36 grams

路路通28克       灵芝25克         当归42克Passepartout 28g Ganoderma lucidum 25g Angelica 42g

桂枝28克         细辛25克         赤芍42克Guizhi 28g Asarum 25g Radix Paeoniae Alba 42g

按规定重量,用常规水提取工艺将延胡索、鸡血藤、路路通、当归、桂枝、细辛、赤芍提取,制成浸膏粉76.8克;将三七、灵芝分别研成细粉,与上述浸膏细粉混合,搅拌均匀,制成细小颗粒,装入0号胶囊,制成中药胶囊492粒。每粒胶囊内含中药细粉及提取物0.28克。According to the specified weight, extract Corydalis Corydalis, Spatholobus Spatholobus, Passepartout, Angelica, Guizhi, Asarum, and Radix Paeoniae Rubra by conventional water extraction process to make 76.8 grams of extract powder; grind Panax notoginseng and Ganoderma lucidum into fine powders , mix with above-mentioned extractum fine powder, stir evenly, make fine granule, pack into No. 0 capsule, make 492 Chinese medicine capsules. Each capsule contains 0.28 grams of traditional Chinese medicine fine powder and extract.

2、取以下配方(重量按克为单位)2. Take the following formula (the weight is in grams)

延胡索130克       鸡血藤190克       三七180克Corydalis Corydalis 130g Spatholobus Spatholobus 190g Panax notoginseng 180g

路路通90克        灵芝55克          当归110克Passepartout 90g Lingzhi 55g Angelica 110g

桂枝90克          细辛60克          赤芍120克Guizhi 90g Asarum 60g Radix Paeoniae Rubra 120g

按上述同样方法,制成中药胶囊1685粒,每粒胶囊内含中药细粉及提取物0.28克。By above-mentioned same method, make 1685 Chinese medicine capsules, every capsule contains Chinese medicine fine powder and extract 0.28 gram.

3、取以下配方(重量按克为单位)3. Take the following formula (the weight is in grams)

延胡索240克       鸡血藤350克       三七250克Corydalis Corydalis 240g Spatholobus Spatholobus 350g Panax notoginseng 250g

路路通180克       灵芝100克         当归250充Passepartout 180g Lingzhi 100g Angelica 250g

桂枝180克             细辛100克            赤芍250克Guizhi 180g Asarum 100g Radix Paeoniae Rubra 250g

按上述同样方法,制成中药胶囊2910粒,每粒胶囊内含中药细粉及提取物0.28克。By above-mentioned same method, make 2910 Chinese medicine capsules, every capsule contains Chinese medicine fine powder and extract 0.28 gram.

4、取以下配方(按重量比)4. Take the following formula (by weight ratio)

延胡索4.2份           鸡血藤5.2份           三七5.5份Corydalis 4.2 parts Spatholobus 5.2 parts Sanqi 5.5 parts

路路通2.3份           灵芝2.5份             当归3.6份Passepartout 2.3 parts Ganoderma lucidum 2.5 parts Angelica 3.6 parts

桂枝3.2份             细辛2.5份             赤芍3.6份Guizhi 3.2 parts Asarum 2.5 parts Radix Paeoniae Rubra 3.6 parts

按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.28克。By the above-mentioned same method, Chinese medicine capsules are made, and each capsule contains 0.28 grams of Chinese medicine fine powder and extract.

5、取以下配方(按重量比)5. Take the following formula (by weight ratio)

延胡索25份           鸡血藤35份          三七25份25 copies of Corydalis Corydalis 35 copies of Caulis Spatholobus 25 copies of Panax notoginseng

路路通15份           灵芝9份             当归22份15 parts of Passepartout 9 parts of Ganoderma lucidum 22 parts of Angelica

桂枝16份             细辛9份             赤芍22份Guizhi 16 parts Asarum 9 parts Radix Paeoniae Rubra 22 parts

按上述同样的方法,制成中药胶囊,每粒胶囊内含中药细粉及提取物0.28克。By the above-mentioned same method, Chinese medicine capsules are made, and each capsule contains 0.28 grams of Chinese medicine fine powder and extract.

临床资料:clinical information:

本发明以中医糖尿病并发肌肉萎缩为例,经12例临床观察。选择中医诊断糖尿病并发肌肉萎缩为标准:糖尿病患者精神萎靡,肢体乏力,肌肉萎缩,肌无力、疼痛、腱反射减弱,神经传导速度减慢。如上症状,即可确诊。在确诊观察的对象中,男性5例,女性7例,无其它严重疾病,年龄为43岁-66岁,平均年龄53.9岁。The present invention takes TCM diabetes complicated by muscle atrophy as an example, through clinical observation of 12 cases. TCM diagnosis of diabetes complicated with muscle atrophy is selected as the standard: diabetic patients are listless, limb fatigue, muscle atrophy, muscle weakness, pain, weakened tendon reflexes, and slowed nerve conduction velocity. The above symptoms can be diagnosed. Among the confirmed observation objects, there were 5 males and 7 females, without other serious diseases, aged 43-66 years, with an average age of 53.9 years.

疗效判定:Judgment of curative effect:

1、显效:体质增强,肢体有力;肌肉萎缩、无力、疼痛等症状明显缓解。1. Significant effect: Physical fitness is enhanced, limbs are strong; muscle atrophy, weakness, pain and other symptoms are significantly relieved.

2、有效:体质增强,肌肉萎缩、无力、疼痛等症状有所缓解。2. Effective: Physical fitness is enhanced, muscle atrophy, weakness, pain and other symptoms are relieved.

3、无效:病症无变化。3. Ineffective: no change in symptoms.

临床实验时,停服其它药物和保健营养品。服用本发明中药胶囊,观察3个月为一个疗程。服用方法:每日3次,每次4粒胶囊,每粒胶囊内含中药细粉及提取物0.28克,饭后温开水送服,1个月后症状即有缓解,服用3个月后,症状明显改善。临床实验的12人中,显效7人,有效5人,总有效率100%。During the clinical trial, stop taking other medicines and health nutrition products. Take Chinese medicine capsule of the present invention, observe 3 months and be a course of treatment. Dosing method: 3 times a day, 4 capsules each time, each capsule contains 0.28 grams of fine powder and extract of traditional Chinese medicine, take it with warm water after meals, the symptoms will be relieved after 1 month, and after 3 months of taking, Symptoms improved significantly. Among the 12 people in the clinical experiment, 7 people were markedly effective, 5 people were effective, and the total effective rate was 100%.

Claims (1)

1. Chinese medicine for the treatment of diabetes mellitus complicated by muscle atrophy, it is characterized in that: it is to make with the raw material of Chinese medicine of following weight ratio:
25 parts of 35 portions of Radix Notoginseng of 25 portions of Caulis Spatholobis of Rhizoma Corydalis
22 parts of 9 parts of Radix Angelicae Sinensis of 15 portions of Ganodermas of Fructus Liquidambaris
22 parts of 9 parts of Radix Paeoniae Rubra of 16 parts of Herba Asaris of Ramulus Cinnamomi
The Chinese medicine of described treatment diabetes mellitus complicated by muscle atrophy is made by following method:
(1) by above-mentioned weight ratio, Rhizoma Corydalis, Caulis Spatholobi, Fructus Liquidambaris, Radix Angelicae Sinensis, Ramulus Cinnamomi, Herba Asari, Radix Paeoniae Rubra are extracted through conventional water extraction process, make the extractum fine powder;
(2) by above-mentioned weight ratio, Radix Notoginseng, Ganoderma are ground into fine powder respectively, mix, stir with above-mentioned extractum fine powder; Make Chinese medicine granules, powder, capsule, watered pill or tablet as required.
CN2008101018420A 2008-03-13 2008-03-13 Traditional Chinese medicine for treating diabetes mellitus and muscle atrophy Expired - Fee Related CN101530479B (en)

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CN115025177B (en) * 2022-07-22 2023-03-21 完美(广东)日用品有限公司 Composition for delaying muscle attenuation and preparation method and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101095938A (en) * 2007-07-05 2008-01-02 北京艺信堂医药研究所 Chinese traditional medicine for treating diabetic ischemic muscular atrophy

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101095938A (en) * 2007-07-05 2008-01-02 北京艺信堂医药研究所 Chinese traditional medicine for treating diabetic ischemic muscular atrophy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
季聚良等.中医药防治糖尿病周围神经病变机制研究概况.<<湖南中医药大学学报>>.2007,第27卷(第2期),76-77. *

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