CN101912511B

CN101912511B - Chinese medicinal preparation for treating qi-blood deficiency polycystic ovary syndrome

Info

Publication number: CN101912511B
Application number: CN2010102579928A
Authority: CN
Inventors: 杨素梅
Original assignee: Individual
Current assignee: Individual
Priority date: 2010-08-09
Filing date: 2010-08-09
Publication date: 2011-11-23
Anticipated expiration: 2030-08-09
Also published as: CN101912511A

Abstract

The invention discloses a Chinese medicinal preparation for treating a qi-blood deficiency polycystic ovary syndrome. Aiming at pathogeny of the polycystic ovary syndrome caused by qi-blood deficiency, panax ginseng, leonurus heterophyllus, cinnamomvine, eucommia bark, dried orange peel, Chinese angelica, root of red-rooted salvia, suberect spatholobus stem and chaff flower root serving as Chinese medicinal herbs which have effects of tonifying spleen and qi and nourishing blood and promoting blood circulation are selected to prepare decoction through scientific compatibility; and one bag is taken by patients every day, the Chinese medicinal preparation is not taken during menstrual period, BBT is monitored during administration, and three months constitute one treatment course. Through clinical verification, the Chinese medicinal preparation improves the clinical symptoms of the patients obviously and improves the ovulation rate and conception rate, has the excellent treatment effect and the total effective rate of 92.5 percent, and is worthy of clinical popularization and application.

Description

A kind of Chinese medicine preparation for the treatment of qi-blood deficiency polycystic ovary syndrome

Technical field

The invention belongs to technical field of Chinese medicines, relate to a kind of Chinese medicine preparation for the treatment of polycystic ovary syndrome.

Background technology

Polycystic ovarian syndrome is women's an a kind of common gynaecopathia, and is very big to women's harm, may cause patient's sterility and infertility.Polycystic ovary syndrome is owing to the imbalance of menstrual regulation mechanism produces, with amenorrhea or hypomenorrhea, infertile, fat, hirsutism and the increase of many capsules of ovary property is the comprehensive syndrome of Clinical symptoms, belongs to categories such as the traditional Chinese medical science " amenorrhea ", " infertile ", " delayed menstrual cycle ".Often there are interior parts such as hyperestrogenism, LH/FSH ratio increase, insulin resistant, female hyperketosis to secrete unusual performance.Especially with shallow complexion, body is thin and weak, have a dizzy spell deficiency of QI with disinclination to talk, weak spontaneous perspiration, palpitation and insomnia, the polycystic ovarian syndrome that QI and blood deficiency such as amenorrhea or metrorrhagia causes is the most common, and at present doctor trained in Western medicine adopts under hormone therapy or the peritoneoscope more the electricity consumption of many capsules follicle is coagulated or operative treatments such as laser technology puncture punching, the excision of ovary wedge, and western medical treatment ovulation rate and abortion ratio height, pregnancy rate are low merely, and can cause ovarian hyperstimulation disease etc., so be difficult for being accepted.

Summary of the invention

The purpose of this invention is to provide a kind of Chinese medicine preparation for the treatment of qi-blood deficiency polycystic ovary syndrome, cause the cause of disease of polycystic ovary syndrome at QI and blood deficiency, selected invigorating the spleen and benefiting QI, the Chinese herbal medicine of blood-nourishing blood-generating, the science compatibility is made decoction.

The objective of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment qi-blood deficiency polycystic ovary syndrome is made by the Chinese herbal medicine of following weight portion: Radix Ginseng 7-9 part, Herba Leonuri 7-9 part, Rhizoma Dioscoreae 5-7 part, Cortex Eucommiae 5-7 part, Pericarpium Citri Reticulatae 3-5 part, Radix Angelicae Sinensis 3-5 part, Radix Salviae Miltiorrhizae 3-5 part, Caulis Spatholobi 1-3 part, Radix Achyranthis Bidentatae 1-3 part.

The Chinese medicine preparation of this treatment qi-blood deficiency polycystic ovary syndrome is made by the Chinese herbal medicine of following optimum weight part: 8 parts of Radix Ginsengs, 8 parts of Herba Leonuris, 6 parts of Rhizoma Dioscoreaes, 6 parts of the Cortexs Eucommiae, 4 parts of Pericarpium Citri Reticulataes, 4 parts of Radix Angelicae Sinensis, 4 parts of Radix Salviae Miltiorrhizaes, 2 parts of Caulis Spatholobis, 2 parts of Radix Achyranthis Bidentataes.

Its preparation method is: take by weighing above-mentioned raw material of Chinese medicine in proportion, cleaning is dried, and is ground into granule, soaks 2 hours, decocts with water twice then, adds the water of 10 times of amounts of crude drug for the first time, after intense fire is fried boiling, slow fire boiling 1-1.5 hour again, gets decocting liquid, filtration.Add for the second time the water of 7 times of amounts of crude drug, decocted 0.5-1 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 200ml, high temperature sterilize, packing is promptly.

Its pharmacological effect: ginseng qi-tonifying takes off spleen invigorating lung benefiting, mind calming Fructus Alpiniae Oxyphyllae, nourishing blood to promote the production of body fluid admittedly in the side; The Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, dampness in the accent; The Rhizoma Dioscoreae supplementing QI and nourishing YIN is mended strengthening spleen and lung, tonifying the kidney to consolidate the essence; The Chinese angelica blood supplementing regulating menstruation. promoting blood circulation and stopping pain; The Radix Salviae Miltiorrhizae promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, nourishing blood to tranquillize the mind; Caulis Spatholobi is enriched blood, and invigorates blood circulation collateral dredging; The Herba Leonuri promoting blood flow to regulate menstruation, inducing diuresis to remove edema; The Radix Achyranthis Bidentatae blood circulation promoting and blood stasis dispelling, invigorating the liver and kidney, bone and muscle strengthening, conducting blood to flow downwards; Cortex Eucommiae invigorating the liver and kidney, bone and muscle strengthening, antiabortive.

Beneficial effect of the present invention: with Chinese medicine decoction treatment qi-blood deficiency polycystic ovary syndrome of the present invention, obviously improved patient's clinical symptoms, improved ovulation rate and pregnancy rate greatly, excellent curative is arranged, be worth clinical application.

Clinical data

1, physical data

Selected 120 routine clinical cases are my institute's in December, 2007-2009 polycystic ovary syndrome that year February, outpatient service was accepted for medical treatment, and wherein the oldest person is 38 years old, reckling 19 years old; Hypomenorrhea 78 examples, secondary amenorrhea 30 examples, irregular metrorrhagia 24 examples; Overweight people's 30 examples (BMI 〉=25 are fat), non-overweight people's 90 examples; Married 68 examples, infertile 50 examples, unmarried 52 examples.

2, Therapeutic Method

Take Chinese medicine decoction of the present invention, 1 bag of every day, withdraw menstrual period, period in a medicine monitoring BBT, and 3 months was 1 course of treatment.

3, criterion of therapeutical effect

Produce effects: the menstruation recovery normal cycle, various symptoms obviously alleviate continuous 3 of menstruation rule more than the cycle after the drug withdrawal, and the hormone value is normal substantially in basal body temperature two-phase or the person's of the becoming pregnant blood, and B ultrasonic shows that ovary recovers normal size.Effectively: menstruation recovers normally substantially, but after the drug withdrawal less than 3 cycle disease relapse persons, various symptoms alleviate to some extent, the hormone value is tending towards normally in the blood, B ultrasonic shows before ovary is than treatment and dwindles.Invalid: menoxenia, various symptoms do not have and alleviate, and basal body temperature is single-phase, and the hormone value does not have significant change in the blood, ovary size no change.

4, therapeutic outcome

With 3 months be 1 course of treatment, the treatment produce effects person's 66 examples (55%); Responder's 46 examples (37.5%); Nonresponder's 9 examples (7.5%); Total effective rate (92.5%).

5, model case

Case 1 Mrs Wang, 30 years old, marry did not have pregnancy 5 years more, and Ceng Qianhou sees a doctor to how tame hospital, and effect is all undesirable, I went to a doctor at institute over 10 years in 2008 upon somebody's introduction, its menstruation of private prosecution is undesired, checks that bilateral ovaries is many capsules and changes mycoplasma, chlamydia infection, be diagnosed as polycystic ovary syndrome, do not ovulate.Take Chinese medicine decoction of the present invention after course of treatment, come my institute to check after, the urine HCG positive, B ultrasonic shows in utero early pregnancy.

Case 2 Mries Li, 32 years old, patient's menoxenia reached 7 years, the beginning 3-5 over the month once, amenorrhea gradually, extremity staple length, the body constitution obesity, through the gynecologial examination of local hospital, left ovary 48 * 37 * 21mm, right ovary 40 * 34 * 222mm size, respectively see more than ten little ovary in the both ovaries, maximum gauge 5-7mm, earlier after how tame hospitalize does not have positive effect, I go to a doctor at institute in January, 2008, the patient takes Chinese medicine decoction of the present invention after course of treatment, menstruation recovery is normal, through ultrasound diagnosis, and left ovary 30 * 21 * 11mm, right ovary 31 * 18 * 13mm, the ovule bubble disappears in two ovum, and check is normal, follows up a case by regular visits to conceived after 1 year.

The specific embodiment

Embodiment one takes by weighing Chinese medicine Radix Ginseng 80g, Herba Leonuri 80g, Rhizoma Dioscoreae 60g, Cortex Eucommiae 60g, Pericarpium Citri Reticulatae 40g, Radix Angelicae Sinensis 40g, Radix Salviae Miltiorrhizae 40g, Caulis Spatholobi 20g, Radix Achyranthis Bidentatae 20g.Cleaning is dried, and is ground into granule, soaks 2 hours, decocts with water twice then, adds the water of 10 times of amounts of crude drug for the first time, after intense fire is fried boiling, slow fire boiling 1-1.5 hour again, gets decocting liquid, filtration.Add for the second time the water of 7 times of amounts of crude drug, decocted 0.5-1 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 200ml, high temperature sterilize, packing is promptly.

Embodiment two takes by weighing Chinese medicine Radix Ginseng 90g, Herba Leonuri 70g, Rhizoma Dioscoreae 70g, Cortex Eucommiae 50g, Pericarpium Citri Reticulatae 30g, Radix Angelicae Sinensis 50g, Radix Salviae Miltiorrhizae 50g, Caulis Spatholobi 10g, Radix Achyranthis Bidentatae 30g.Cleaning is dried, and is ground into granule, soaks 2 hours, decocts with water twice then, adds the water of 10 times of amounts of crude drug for the first time, after intense fire is fried boiling, slow fire boiling 1-1.5 hour again, gets decocting liquid, filtration.Add for the second time the water of 7 times of amounts of crude drug, decocted 0.5-1 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 200ml, high temperature sterilize, packing is promptly.

Embodiment three takes by weighing Chinese medicine Radix Ginseng 70g, Herba Leonuri 90g, Rhizoma Dioscoreae 50g, Cortex Eucommiae 70g, Pericarpium Citri Reticulatae 50g, Radix Angelicae Sinensis 30g, Radix Salviae Miltiorrhizae 30g, Caulis Spatholobi 30g, Radix Achyranthis Bidentatae 10g.Cleaning is dried, and is ground into granule, soaks 2 hours, decocts with water twice then, adds the water of 10 times of amounts of crude drug for the first time, after intense fire is fried boiling, slow fire boiling 1-1.5 hour again, gets decocting liquid, filtration.Add for the second time the water of 7 times of amounts of crude drug, decocted 0.5-1 hour, get decocting liquid twice, filter, in the heat-sealing bag, every bag of 200ml, high temperature sterilize, packing is promptly.

Claims

1. a Chinese medicine preparation for the treatment of qi-blood deficiency polycystic ovary syndrome is characterized in that being made by the Chinese herbal medicine of following weight portion: Radix Ginseng 7-9 part, Herba Leonuri 7-9 part, Rhizoma Dioscoreae 5-7 part, Cortex Eucommiae 5-7 part, Pericarpium Citri Reticulatae 3-5 part, Radix Angelicae Sinensis 3-5 part, Radix Salviae Miltiorrhizae 3-5 part, Caulis Spatholobi 1-3 part, Radix Achyranthis Bidentatae 1-3 part.

2. a kind of Chinese medicine preparation for the treatment of qi-blood deficiency polycystic ovary syndrome according to claim 1 is characterized in that being made by the Chinese herbal medicine of following optimum weight part: 8 parts of Radix Ginsengs, 8 parts of Herba Leonuris, 6 parts of Rhizoma Dioscoreaes, 6 parts of the Cortexs Eucommiae, 4 parts of Pericarpium Citri Reticulataes, 4 parts of Radix Angelicae Sinensis, 4 parts of Radix Salviae Miltiorrhizaes, 2 parts of Caulis Spatholobis, 2 parts of Radix Achyranthis Bidentataes.