CN103156981A - Traditional Chinese medicine composition for treating uterine hypoplasia, and preparation method and application thereof - Google Patents
Traditional Chinese medicine composition for treating uterine hypoplasia, and preparation method and application thereof Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine composition for treating uterine hypoplasia, a preparation method thereof and application of the composition in preparation of a medicine used for treating uterine hypoplasia. The composition comprises the following bulk drugs: human placenta, dodder seed, epimedium herb, barbary wolfberry fruit, morinda root, degelatined deer-horn, fluorite, desertliving cistanche, tortoise carapace and plastron, asiatic cornelian cherry fruit, tuber onion seed, Chinese angelica, cibot rhizome, Indian bread, common yam rhizome, debark peony root, ginseng and largehead atractylodes rhizome. The traditional Chinese medicine composition can be prepared by using a conventional traditional Chinese medicine preparation method to obtain a clinically applicable preparation; preferably, the preparation is an oral preparation or an externally applied preparation; and more preferably, the oral preparation is a decoction, and the externally applied preparation is an externally applied powder. The invention has the following characteristics: the traditional Chinese medicine composition has a remarkable curative effect no toxic and side effects, and the preparation method is simple.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, particularly relate to a kind of Chinese medicine composition that is used for the treatment of uterine hypoplasia and preparation method thereof and the application in preparation treatment uterine hypoplasia medicine.
Background technology
Uterine hypoplasia claims again uterine hypoplasia, refer generally to adolescence after the uterus still less than normally, be commonly called as " uterus is little ".Such patient is often with infrequent menstruation, menolipsis or amenorrhea.Uterine hypoplasia is to be due to stasi in short-term after gyneduct is joined, and the uterus compared with normal is little, extremely first bending or rear bending sometimes, and it is conical that cervix uteri is, and relatively long, the palace body is 1: 1 or 2: 3 with the ratio of cervix uteri.Above deformity causes uterus normally accumulating seminal fluid and sperm, and sperm can't be obtained and become pregnant; Uterus shape and volume are abnormal, and the myometrium dysplasia is unfavorable for implantation of ovum, implantation and fetal development, easily cause abortion in first trimester, the symptoms such as site is abnormal, fetal development is slow, sterility and infertility.Doctor trained in Western medicine mainly adopts hormone therapy and operative treatment, and hormone therapy has larger side effect to health, and operative treatment needs long convalescent period and certain risk is arranged, and patient's psychology is caused burden.The traditional Chinese medical science is divided into the dialectical treatment of disease type such as suffer from a deficiency of the kidney of the cold womb of suffering from a deficiency of the kidney, asthenia of both the spleen and kidney, deficiency of kidney-essence, stagnation of liver-QI clinically, the Chinese medicine preparation of existing treatment uterine hypoplasia is reaching therapeutic effect in varying degrees, but mostly still there are the defectives such as materials are complicated, preparation is loaded down with trivial details, curative effect is remarkable not, have much room for improvement.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of evident in efficacy, Chinese medicine composition of having no side effect, preparing simple treatment uterine hypoplasia and preparation method thereof and the application in preparation treatment uterine hypoplasia medicine.
For reaching above-mentioned purpose, a kind of Chinese medicine composition for the treatment of uterine hypoplasia of the present invention comprises following crude drug: Placenta Hominis, Semen Cuscutae, Herba Epimedii, Fructus Lycii, Radix Morindae Officinalis, Cornu Cervi Degelatinatum, Fluoritum, Herba Cistanches, Carapax Et Plastrum Testudinis, Fructus Corni, Semen Allii Tuberosi, Radix Angelicae Sinensis, Rhizoma Cibotii, Poria, Rhizoma Dioscoreae, the Radix Paeoniae Alba, Radix Ginseng and the Rhizoma Atractylodis Macrocephalae.
The present invention treats the Chinese medicine composition of uterine hypoplasia, and the weight portion of wherein said each crude drug is: Placenta Hominis 10-20 part, Semen Cuscutae 5-15 part, Herba Epimedii 10-15 part, Fructus Lycii 8-12 part, Radix Morindae Officinalis 8-12 part, Cornu Cervi Degelatinatum 6-10 part, Fluoritum 8-10 part, Herba Cistanches 6-10 part, Carapax Et Plastrum Testudinis 8-12 part, Fructus Corni 8-12 part, Semen Allii Tuberosi 8-12 part, Radix Angelicae Sinensis 6-10 part, Rhizoma Cibotii 8-12 part, Poria 8-12 part, Rhizoma Dioscoreae 8-12 part, Radix Paeoniae Alba 8-12 part, Radix Ginseng 6-10 part, Rhizoma Atractylodis Macrocephalae 8-12 part.Preferably, 15 parts of Placenta Hominiss, 10 parts of Semen Cuscutae, 12 parts of Herba Epimedii, 10 parts of Fructus Lycii, 10 parts of Radix Morindae Officinaliss, 8 parts of Cornu Cervi Degelatinatums, 9 parts of Fluoritum, 8 parts of Herba Cistanches, 10 parts of Carapax Et Plastrum Testudiniss, 10 parts of Fructus Corni, 10 parts of Semen Allii Tuberosi, 8 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Cibotii, 10 parts, Poria, 10 parts of Rhizoma Dioscoreaes, 10 parts of the Radix Paeoniae Albas, 8 parts of Radix Ginsengs, 10 parts of the Rhizoma Atractylodis Macrocephalaes.
The present invention's crude drug used all can be bought from common Chinese material shop and obtain, and its specification meets national Chinese crude drug standard and gets final product.
Chinese medicine composition of the present invention can be prepared into any suitable preparation clinically according to Chinese medicine conventional formulation method.Preferred described preparation is oral formulations or external preparation, and more preferably described oral formulations is water decoction, and described external preparation is external pulvis.
A kind of method for preparing above-mentioned Chinese medicine composition comprises the following steps:
(1) take each crude drug by described weight;
(2) said medicine is mixed be placed on and add water in marmite and do not have powder, soak after 20～40 minutes and decoct again, renew after boiling and fry in shallow oil 30 minutes, decoct altogether three times, merges three decocting liquids filtrations, obtain water decoction.Each serving with 150 milliliters, take night and morning, take half an hour ante cibum, and be a course for the treatment of January.
A kind of method of above-mentioned Chinese medicine composition comprises the following steps:
(1) take each crude drug by described weight;
(2) each crude drug is pulverized, be in harmonious proportion evenly with 50 degree Chinese liquor, namely get external pulvis.During use, get on the appropriate external application patient's of this powder umbilicus, then use immobilization with adhesive tape, changed dressings once in 7th, changing dressings 15 times is a course for the treatment of.
The medicine that uterine hypoplasia is treated in preparation is used it in the application of Chinese medicine composition of the present invention.
Chinese medicine composition of the present invention contains Placenta Hominis, Cornu Cervi Degelatinatum, the raw medicinal materials such as Carapax Et Plastrum Testudinis, effect with life essence-filling, marrow-benefitting, utilize its flesh and blood that the thing of essence is arranged, impel the growth promoter of body of uterus, contain a large amount of gonadotropin and vitamin A in this type of medicine in addition, the trace element such as vitamin B, and have can excited hypothalamus, hypophysis, the function of hypothalamic pituitary ovarium axis, with Semen Cuscutae, Herba Epimedii, Radix Morindae Officinalis, Fluoritum, Herba Cistanches, Semen Allii Tuberosi, the Rhizoma Cibotii kidney invigorating and YANG supporting, and the function of endocrine regulation arranged, with Fructus Lycii, Fructus Corni, the Rhizoma Dioscoreae the kidney invigorating and essence nourishing, tonifying Chong and Ren channels, with Radix Salviae Miltiorrhizae, the Rhizoma Atractylodis Macrocephalae, Poria, Radix Angelicae Sinensis, Radix Paeoniae Alba benefiting QI and nourishing blood, mend the day after tomorrow to support congenital defect, and can improve hormonal readiness, thereby improve menstruation.Chinese liquor has the effect of blood circulation promoting and blood stasis dispelling, Transdermal absorption in addition.In addition, Chinese medicine composition of the present invention also can pass through this specific channel of umbilicus " SHENQUE acupoint ", can act on rapidly body, makes equilibrium between yin and yang, and function is recovered, have evident in efficacy, have no side effect, the simple characteristics of preparation method.
The specific embodiment
Be described in more detail with other technical characterictic and advantage the present invention is above-mentioned below in conjunction with embodiment.
The preparation of embodiment 1 water decoction
Take following raw medicinal material:
Placenta Hominis 10g, Semen Cuscutae 5g, Herba Epimedii 10g, Fructus Lycii 8g, Radix Morindae Officinalis 8g, Cornu Cervi Degelatinatum 6g, Fluoritum 8g, Herba Cistanches 6g, Carapax Et Plastrum Testudinis 8g, Fructus Corni 8g, Semen Allii Tuberosi 8g, Radix Angelicae Sinensis 6g, Rhizoma Cibotii 8g, Poria 8g, Rhizoma Dioscoreae 8g, Radix Paeoniae Alba 8g, Radix Ginseng 6g, Rhizoma Atractylodis Macrocephalae 8g.
Said medicine is mixed to be placed on add water in marmite and do not have powder, soak after 20 minutes and decoct again, fried in shallow oil continuously again 30 minutes after boiling, repeat altogether to decoct three times, filter and discard medicinal residues, three decocting liquids are merged, obtain water decoction.
The preparation of embodiment 2 water decoctions
Take following raw medicinal material:
Placenta Hominis 20g, Semen Cuscutae 15g, Herba Epimedii 15g, Fructus Lycii 12g, Radix Morindae Officinalis 12g, Cornu Cervi Degelatinatum 10g, Fluoritum 10g, Herba Cistanches 10g, Carapax Et Plastrum Testudinis 12g, Fructus Corni 12g, Semen Allii Tuberosi 12g, Radix Angelicae Sinensis 10g, Rhizoma Cibotii 12g, Poria 12g, Rhizoma Dioscoreae 12g, Radix Paeoniae Alba 12g, Radix Ginseng 10g, Rhizoma Atractylodis Macrocephalae 12g.
Said medicine is mixed to be placed on add water in marmite and do not have powder, soak after 40 minutes and decoct again, fried in shallow oil continuously again 30 minutes after boiling, repeat altogether to decoct three times, filter and discard medicinal residues, three decocting liquids are merged, obtain water decoction.
The preparation of embodiment 3 water decoctions
Take following raw medicinal material:
Placenta Hominis 15g, Semen Cuscutae 10g, Herba Epimedii 12g, Fructus Lycii 10g, Radix Morindae Officinalis 10g, Cornu Cervi Degelatinatum 8g, Fluoritum 9g, Herba Cistanches 8g, Carapax Et Plastrum Testudinis 10g, Fructus Corni 10g, Semen Allii Tuberosi 10g, Radix Angelicae Sinensis 8g, Rhizoma Cibotii 10g, Poria 10g, Rhizoma Dioscoreae 10g, Radix Paeoniae Alba 10g, Radix Ginseng 8g, Rhizoma Atractylodis Macrocephalae 10g.
Said medicine is mixed to be placed on add water in marmite and do not have powder, soak after 30 minutes and decoct again, fried in shallow oil continuously again 30 minutes after boiling, repeat altogether to decoct three times, filter and discard medicinal residues, three decocting liquids are merged, obtain water decoction.
The preparation of embodiment 4 external pulvis
Take following raw medicinal material:
Placenta Hominis 10g, Semen Cuscutae 5g, Herba Epimedii 10g, Fructus Lycii 8g, Radix Morindae Officinalis 8g, Cornu Cervi Degelatinatum 6g, Fluoritum 8g, Herba Cistanches 6g, Carapax Et Plastrum Testudinis 8g, Fructus Corni 8g, Semen Allii Tuberosi 8g, Radix Angelicae Sinensis 6g, Rhizoma Cibotii 8g, Poria 8g, Rhizoma Dioscoreae 8g, Radix Paeoniae Alba 8g, Radix Ginseng 6g, Rhizoma Atractylodis Macrocephalae 8g.
Each crude drug is pulverized, be in harmonious proportion evenly with front use 50 degree Chinese liquor temporarily, namely get external pulvis.
The preparation of embodiment 5 external pulvis
Take following raw medicinal material:
Placenta Hominis 20g, Semen Cuscutae 15g, Herba Epimedii 15g, Fructus Lycii 12g, Radix Morindae Officinalis 12g, Cornu Cervi Degelatinatum 10g, Fluoritum 10g, Herba Cistanches 10g, Carapax Et Plastrum Testudinis 12g, Fructus Corni 12g, Semen Allii Tuberosi 12g, Radix Angelicae Sinensis 10g, Rhizoma Cibotii 12g, Poria 12g, Rhizoma Dioscoreae 12g, Radix Paeoniae Alba 12g, Radix Ginseng 10g, Rhizoma Atractylodis Macrocephalae 12g.
Each crude drug is pulverized, be in harmonious proportion evenly with front use 50 degree Chinese liquor temporarily, namely get external pulvis.
The preparation of embodiment 6 external pulvis
Take following raw medicinal material:
Placenta Hominis 15g, Semen Cuscutae 10g, Herba Epimedii 12g, Fructus Lycii 10g, Radix Morindae Officinalis 10g, Cornu Cervi Degelatinatum 8g, Fluoritum 9g, Herba Cistanches 8g, Carapax Et Plastrum Testudinis 10g, Fructus Corni 10g, Semen Allii Tuberosi 10g, Radix Angelicae Sinensis 8g, Rhizoma Cibotii 10g, Poria 10g, Rhizoma Dioscoreae 10g, Radix Paeoniae Alba 10g, Radix Ginseng 8g, Rhizoma Atractylodis Macrocephalae 10g.
Each crude drug is pulverized, be in harmonious proportion evenly with front use 50 degree Chinese liquor temporarily, namely get external pulvis.
Test example Chinese medicine composition of the present invention is abnormal at various abortion in first trimester, site that the treatment uterine hypoplasia causes, the clinical efficacy of the symptoms such as fetal development is slow, sterility and infertility is summed up.
Between 2000 to 2010 10 years, traditional Chinese medicine composition for treating uterine hypoplasia patient of the present invention 356 examples, wherein cured person 221 examples account for 62%, and improvement person's 109 examples account for 30.6%, and nonresponder's 26 examples account for 7.3%, effective percentage 92.6%.During treatment, patient illustrates Chinese medicine composition drug safety of the present invention without the secondary untoward reaction of any poison, has no side effect.
Clinical model case:
Case 1, Xu certain, the female, 15 years old, height and weight was normal, through health check-up also without the malnutrition situation, but menstruation does not slowly have, and is the less dysplasia in uterus to hospital through ultrasound diagnosis, and certain began Xu with external pulvis treatment of the present invention from March, 2007, get appropriate outer the spreading on umbilicus of powder, then fix with medical adhesive tape, changed dressings once in 7th, after half a year, certain physical recovery of Xu is normal, the eumenorrhea, returns to one's perfect health.
Case 2, Lee, female, 22 years old, disease is infrequent menstruation, dysmenorrhea, takes the medicine of various a large amount for the treatment of regulating menoxenias, all cures the symptoms, not the disease, but also has formed drug dependence, need the medication alleviating pain each menstrual period, but menstruation is still rare, and rear diagnosis is that uterine hypoplasia causes.Lee begins to take Chinese medicine composition of the present invention from May, 2005, takes night and morning, and take half an hour ante cibum, after taking January, the dysmenorrhea symptom takes a turn for the better, after taking three months, essentially no dysmenorrhea symptom, and menstrual blood volume is more on the high side than in the past, approaches normally, after Lee adheres to having taken half a year, symptom in the past disappears fully, use ultrasound diagnosis, the uterus has obviously grows phenomenon again, and health returns to one's perfect health.
Case 3, the Meng, female, 32 years old, the unpregnancy for many years of marrying, after be diagnosed as the uterus congenital malformation, before this through hormone therapy by operative treatment, the treatment of advancing more than 2 years is still invalid, upon somebody's introduction, takes Chinese medicine composition of the present invention, oral and external combines, conceived after half a year, full-term normal delivery one boy weighs three jin six liang.
Case 4, Wei, female, 16 years old, original eumenorrhea, the fat-reducing of going on a diet because body weight is partially fat, allay one's hunger with apotrophic foods low in calories such as Fructus Cucumidiss sativi every day, after two months, ischomenia, by the uterine hypoplasia that is diagnosed as the adolescence malnutrition and causes, take Chinese medicine of the present invention after one month, it is normal that menstruation recovers substantially.
Above-described embodiment is described the preferred embodiment of the present invention; be not that scope of the present invention is limited; design under the prerequisite of spirit not breaking away from the present invention; various distortion and improvement that those of ordinary skills make technical scheme of the present invention all should fall in the definite protection domain of claims of the present invention.
Claims (8)
1. Chinese medicine composition for the treatment of uterine hypoplasia, it is characterized in that, comprise following crude drug: Placenta Hominis, Semen Cuscutae, Herba Epimedii, Fructus Lycii, Radix Morindae Officinalis, Cornu Cervi Degelatinatum, Fluoritum, Herba Cistanches, Carapax Et Plastrum Testudinis, Fructus Corni, Semen Allii Tuberosi, Radix Angelicae Sinensis, Rhizoma Cibotii, Poria, Rhizoma Dioscoreae, the Radix Paeoniae Alba, Radix Ginseng and the Rhizoma Atractylodis Macrocephalae.
2. Chinese medicine composition according to claim 1, it is characterized in that, the weight portion of described each crude drug is: Placenta Hominis 10-20 part, Semen Cuscutae 5-15 part, Herba Epimedii 10-15 part, Fructus Lycii 8-12 part, Radix Morindae Officinalis 8-12 part, Cornu Cervi Degelatinatum 6-10 part, Fluoritum 8-10 part, Herba Cistanches 6-10 part, Carapax Et Plastrum Testudinis 8-12 part, Fructus Corni 8-12 part, Semen Allii Tuberosi 8-12 part, Radix Angelicae Sinensis 6-10 part, Rhizoma Cibotii 8-12 part, Poria 8-12 part, Rhizoma Dioscoreae 8-12 part, Radix Paeoniae Alba 8-12 part, Radix Ginseng 6-10 part, Rhizoma Atractylodis Macrocephalae 8-12 part.
3. Chinese medicine composition according to claim 2, it is characterized in that, the weight portion of described each crude drug is: 15 parts of Placenta Hominiss, 10 parts of Semen Cuscutae, 12 parts of Herba Epimedii, 10 parts of Fructus Lycii, 10 parts of Radix Morindae Officinaliss, 8 parts of Cornu Cervi Degelatinatums, 9 parts of Fluoritum, 8 parts of Herba Cistanches, 10 parts of Carapax Et Plastrum Testudiniss, 10 parts of Fructus Corni, 10 parts of Semen Allii Tuberosi, 8 parts of Radix Angelicae Sinensis, 10 parts of Rhizoma Cibotii, 10 parts, Poria, 10 parts of Rhizoma Dioscoreaes, 10 parts of the Radix Paeoniae Albas, 8 parts of Radix Ginsengs, 10 parts of the Rhizoma Atractylodis Macrocephalaes.
4. the described Chinese medicine composition of claim 1-3 any one is characterized in that: be prepared into any suitable preparation clinically according to Chinese medicine conventional formulation method.
5. Chinese medicine composition according to claim 4, it is characterized in that: described preparation is oral formulations or external preparation, and described oral formulations is water decoction, and described external preparation is external pulvis.
6. a method for preparing the described Chinese medicine composition of claim 1-3 any one, is characterized in that, comprises the following steps:
(1) take each crude drug by described weight;
(2) said medicine is mixed be placed on and add water in marmite and do not have powder, soak after 20～40 minutes and decoct again, renew after boiling and fry in shallow oil 30 minutes, decoct altogether three times, merges three decocting liquids filtrations, obtain water decoction.
7. a method for preparing the described Chinese medicine composition of claim 1-3 any one, is characterized in that, comprises the following steps:
(1) take each crude drug by described weight;
(2) each crude drug is pulverized, be in harmonious proportion evenly with 50 degree Chinese liquor, namely get external pulvis.
8. the application of the described Chinese medicine composition of claim 1-3 any one is characterized in that: the medicine of using it for preparation treatment uterine hypoplasia.
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN104107313A (en) * | 2013-07-27 | 2014-10-22 | 成都绿迪科技有限公司 | Traditional Chinese medicine composition used for treating kidney-deficiency liver-depression type breast distention before menstruation |
| CN104208579A (en) * | 2014-08-25 | 2014-12-17 | 周希潭 | Medicine composition comprising ginseng, fructus lycii, angelica sinensis and rhizoma atractylodis macrocephalae and preparation method thereof |
| CN104491654A (en) * | 2014-12-12 | 2015-04-08 | 高怀秀 | Medicament for treating hypoplasia of uterus and preparation method of medicament |
| CN104645030A (en) * | 2014-03-11 | 2015-05-27 | 潍坊医学院 | Traditional Chinese medicine for treating blocking-antibody-deficiency type recurrent spontaneous abortion |
| CN104740299A (en) * | 2014-03-11 | 2015-07-01 | 潍坊医学院 | Traditional Chinese medicine for treating recurrent spontaneous abortion caused by insufficiency of blocking antibody |
| CN110585369A (en) * | 2019-10-14 | 2019-12-20 | 天津中医药大学第一附属医院 | Traditional Chinese medicine composition for improving endometrial receptivity and application thereof |
| CN113425796A (en) * | 2021-08-17 | 2021-09-24 | 郑小春 | A Chinese medicinal composition for treating infertility, and its preparation method |
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| CN101028376A (en) * | 2007-04-16 | 2007-09-05 | 北京艺信堂医药研究所 | Chinese medicinal preparation for treating habitual abortion |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101028376A (en) * | 2007-04-16 | 2007-09-05 | 北京艺信堂医药研究所 | Chinese medicinal preparation for treating habitual abortion |
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| CN104107313A (en) * | 2013-07-27 | 2014-10-22 | 成都绿迪科技有限公司 | Traditional Chinese medicine composition used for treating kidney-deficiency liver-depression type breast distention before menstruation |
| CN104645030A (en) * | 2014-03-11 | 2015-05-27 | 潍坊医学院 | Traditional Chinese medicine for treating blocking-antibody-deficiency type recurrent spontaneous abortion |
| CN104740299A (en) * | 2014-03-11 | 2015-07-01 | 潍坊医学院 | Traditional Chinese medicine for treating recurrent spontaneous abortion caused by insufficiency of blocking antibody |
| CN104740299B (en) * | 2014-03-11 | 2018-02-27 | 潍坊医学院 | A kind of Chinese medicine for treating blocking antibody shortage type recurrent spontaneous abortion |
| CN104645030B (en) * | 2014-03-11 | 2018-05-29 | 潍坊医学院 | Treat the Chinese medicine of blocking antibody shortage type recurrent spontaneous abortion |
| CN104208579A (en) * | 2014-08-25 | 2014-12-17 | 周希潭 | Medicine composition comprising ginseng, fructus lycii, angelica sinensis and rhizoma atractylodis macrocephalae and preparation method thereof |
| CN104208579B (en) * | 2014-08-25 | 2018-02-16 | 浙江八味保健食品有限公司 | One seed ginseng Qi returns art pharmaceutical composition and preparation method thereof |
| CN104491654A (en) * | 2014-12-12 | 2015-04-08 | 高怀秀 | Medicament for treating hypoplasia of uterus and preparation method of medicament |
| CN110585369A (en) * | 2019-10-14 | 2019-12-20 | 天津中医药大学第一附属医院 | Traditional Chinese medicine composition for improving endometrial receptivity and application thereof |
| CN113425796A (en) * | 2021-08-17 | 2021-09-24 | 郑小春 | A Chinese medicinal composition for treating infertility, and its preparation method |
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