CN103110798B - Chinese medicinal formula for treating menstrual disorder type infertility and preparation method thereof - Google Patents

Chinese medicinal formula for treating menstrual disorder type infertility and preparation method thereof Download PDF

Info

Publication number
CN103110798B
CN103110798B CN201310017193.7A CN201310017193A CN103110798B CN 103110798 B CN103110798 B CN 103110798B CN 201310017193 A CN201310017193 A CN 201310017193A CN 103110798 B CN103110798 B CN 103110798B
Authority
CN
China
Prior art keywords
radix
parts
fructus
simmer
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201310017193.7A
Other languages
Chinese (zh)
Other versions
CN103110798A (en
Inventor
陈方
于建敏
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ran Hongtu
Zhejiang Hongsheng Technology Transfer Services Co ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201310017193.7A priority Critical patent/CN103110798B/en
Publication of CN103110798A publication Critical patent/CN103110798A/en
Application granted granted Critical
Publication of CN103110798B publication Critical patent/CN103110798B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Landscapes

  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a Chinese medicinal formula for treating menstrual disorder type infertility, which mainly comprises radix angelicae sinensis, radix rehmanniae preparata, white paeony root, radix pseudostellariae, plantago asiatica, China dodder, lycium barbarum, herb of shorthorned epimedium, rubus idaeus, cornus officinalis, radix polygoni multiflori, cornu cervi degelatinatum, cochinchinese asparagus root and fructus forsythia. The Chinese medicinal formula has the effects on enriching the blood and regulating menstruation, and has obvious cure effect on the menstrual disorder type infertility.

Description

A kind of Chinese medicinal formulae for the treatment of menoxenia type infertility and preparation method thereof
Technical field
The invention discloses a kind of Chinese medicinal formulae, especially treat Chinese medicinal formulae of menoxenia barrenness and preparation method thereof.Belong to Chinese medicine field.
Background technology
Infertile medical definition is within 1 year, not take any contraceptives, and sexual life does not normally have successful pregnancy.Cause that infertile pathogenic factor is divided into male infertility and female acyesis, 1992 by World Health Organization (WHO) in diagnosis and this classification of extensive use for the treatment of infertility.In developed country, SF factor accounts for 37%, and male factor accounts for 8%; Both sides factor accounts for 35%, does not find that infertile (fertility) of reason accounts for 5%.The actual percentage of infertile independent primary factor is widely different between difference research.But, one exceedes 20 and studies more widely infertile meta-analysis and find, primary etiological diagnosis successively: infertile (17%) of ovulation failure (27%), dysspermatism (25%), oviduct abnormality (22%), unknown cause, endometriosis (5%) and other as infertile in immunology (4%).Factor is cervix uteri factor in addition, comprises that accounting for all cervix uteri factors exceedes 5% cervical stenosis.Female acyesis is mainly with ovulation failure, fallopian tube factor, and endometrium receptivity is main extremely, male infertility is mainly the abnormal and ejaculation obstacle of spermatogenesis.
Menoxenia is a general designation, and it comprises that menstruation shifts to an earlier date, delays, irregularly, menorrhagia, very few etc.From the angle of modern medicine, menoxenia can be explained from reproductive endocrine, nerve, immune imbalance; From the angle of the traditional Chinese medical science, menoxenia liver,spleen,kidney functional disorder obstructed with insufficiency of vital energy and blood, visceral dysfunction, the especially traditional Chinese medical science is closely related.
Menoxenia barrenness, refers to the long-term menstruation entanglement of women, and the matrimonial cohabitation person that do not become pregnant above for 3 years, is one of gynecological clinic commonly encountered diseases.Menoxenia barrenness basis for estimation is: the long-term menstruation entanglement of women, matrimonial cohabitation is not become pregnant for 3 years above.Menstrual period or before or after, or the several months one to, or January number extremely, very amenorrhea.More or less mensis in amount, light or purple through color, or abdominal pain during menstruation, or stomachache before and after menstrual period.Or with adnexitis, fallopian tube enclosed mass, uterine hypoplasia, endometritis etc.
Chinese medicine thinks how infertilitas feminis does not save kidney essense by natural endowment deficiency, chamber and do not fill, and rushes conception vessel void, or deficiency of kidney yin, uterus cold caused by deficiency, or plain body weakness, and deficiency of YIN-blood, vessels of the uterus loses supports; Or feelings will is not smooth, depression of liver-QI, qi-blood disharmony; Or plain body obesity, throw off restraint food greasy and surfeit flavour, and deficiency of spleen-YANG and kidneyYANG, accumulates raw phlegm-damp, mechanism of qi retardance, and punching is appointed obstructed; Or blood stasis condenses, lump in the abdomen, amasss in born of the same parents are medium and causes.The reason that causes female acyesis is many-sided, but many and menoxenia is in close relations, therefore, and traditional Chinese medical science opinion " female acyesis focuses on regulating menstruation ".
In the method for existing treatment menoxenia barrenness, Chinese patent CN03106271.7 discloses a kind of " Tiaojing Cuyun Chinese medicine and preparation method " by name in 2003, formed by Radix Angelicae Sinensis, Rhizoma Chuanxiong, Fructus Amomi, Flos Carthami, Radix Rehmanniae Preparata, Radix Notoginseng powder, Radix Bupleuri, the Radix Paeoniae Alba, prescription is simple, curative effect is single, and Radix Notoginseng, Flos Carthami in side, be the medical material that anemia of pregnant woman is cautious use of, and pregnant front excessive use is very easily harmful to the health.
Summary of the invention
For the present situation of existing treatment menoxenia barrenness deficiency, one of object of the present invention is to provide a kind of Chinese medicinal formulae for the treatment of menoxenia barrenness, there is feature easy to operate, evident in efficacy, and its adopts, and comparatively common Chinese crude drug is as raw material, with low cost in the localities.
Another object of the present invention is to provide the preparation method of above-mentioned Chinese medicinal formulae.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Treat a Chinese medicinal formulae for menoxenia barrenness, preferred scheme, takes off the primary raw material of stating weight proportion and is prepared from: Radix Angelicae Sinensis 6-12 part, Radix Rehmanniae Preparata 10-30 part, Radix Paeoniae Alba 10-15 part, Radix Pseudostellariae 10-30 part is (preferred, Radix Pseudostellariae 10.5-29 part), Semen Plantaginis 6-15 part, Semen Cuscutae 9-15 part, Fructus Lycii 6-12 part, Herba Epimedii 3-9 part, Fructus Rubi 5-10 part, Fructus Corni 6-12 part, Radix Polygoni Multiflori 6-12 part, Cornu Cervi Degelatinatum 9-15 part, Radix Asparagi 15-30 part, Fructus Forsythiae 6-15 part.
Treat a Chinese medicinal formulae for menoxenia barrenness, the scheme being more preferably, takes off the primary raw material of stating weight proportion and is prepared from: Radix Angelicae Sinensis 8-10 part, Radix Rehmanniae Preparata 15-25 part, Radix Paeoniae Alba 11-14 part, Radix Pseudostellariae 15-25 part, Semen Plantaginis 8-12 part, Semen Cuscutae 10-14 part, Fructus Lycii 8-10 part, Herba Epimedii 5-8 part, Fructus Rubi 7-9 part, Fructus Corni 8-11 part, Radix Polygoni Multiflori 8-10 part, Cornu Cervi Degelatinatum 10-14 part, Radix Asparagi 20-28 part, Fructus Forsythiae 8-12 part.
Treat a Chinese medicinal formulae for menoxenia barrenness, best scheme, takes off the primary raw material of stating weight proportion and is prepared from: 9 parts of Radix Angelicae Sinensis, 20 parts of Radix Rehmanniae Preparata, 12 parts of the Radix Paeoniae Albas, 20 parts of Radix Pseudostellariaes, 10 parts of Semen Plantaginiss, 12 parts of Semen Cuscutae, 9 parts of Fructus Lycii, 7 parts of Herba Epimedii, 8 parts of Fructus Rubies, 10 parts of Fructus Corni, 9 parts of Radix Polygoni Multiflori, 12 parts of Cornu Cervi Degelatinatums, 25 parts of Radix Asparagis, 10 parts of Fructus Forsythiaes.
The preparation method of above-mentioned arbitrary Chinese medicinal formulae, preparation process is as follows:
1. the Radix Paeoniae Alba is mixed thoroughly with appropriate yellow wine sprinkle, be then placed in pot fried dry, obtain Radix Paeoniae Alba, dry in the air cool for subsequent use;
2. Radix Polygoni Multiflori is mixed thoroughly with decoction of black soybean, put in the appropriate vessel of non iron, stew or steam to juice and exhaust, inside and outside while being all sepia, the air dry of drying in the air is dry, obtains Radix Polygoni Multiflori Preparata for subsequent use;
3. Cornu Cervi Degelatinatum is placed in to intense fire in marmite and is fried open, turn 20-45 minute at a simmer, then put into Radix Angelicae Sinensis, Radix Rehmanniae Preparata, 12 parts of Radix Paeoniae Alba, Radix Pseudostellariae, Semen Plantaginis, Semen Cuscutae, Fructus Lycii, Herba Epimedii, Fructus Rubi, Fructus Corni, Radix Polygoni Multiflori Preparata, Radix Asparagi, Fructus Forsythiae intense fire is fried open, turn 15-40 minute at a simmer, leach medicinal liquid;
4. recrement is watered intense fire again and is fried open, and turns 15-30 minute at a simmer, and twice medicinal liquid mixes.
The preparation method of above-mentioned Chinese medicinal formulae, 3. step is placed in Cornu Cervi Degelatinatum intense fire in marmite and is fried open, and turns 20-45 at a simmer minute (preferably 25-35 minute, is more preferably 30 minutes).
The preparation method of above-mentioned Chinese medicinal formulae, 3. step turns 15-40 at a simmer minute (preferably 20-35 minute, is more preferably 25 minutes), leaches medicinal liquid.
The preparation method of above-mentioned Chinese medicinal formulae, 4. step turns 15-30 at a simmer minute (preferably 18-25 minute, is more preferably 20 minutes), and twice medicinal liquid mixes.
Using method: for making the present invention reach optimum therapeuticing effect, Chinese medicine decoction of the present invention, every day twice, in sooner or later taking half an hour after meal, cut out menstrual period.
This Chinese medicinal formulae is remarkable to menoxenia barrenness effect, not only makes patient be pregnant to nurse a baby youngster to do mother's right, also has menstruction regulating and pain relieving, is that menstruation recovery is normal, conditioning complexion.Local common medical material for multiselect of the present invention, cheap, alleviate patient's financial burden.
The pharmacological effect of each crude drug is respectively: 9 parts of Radix Angelicae Sinensis, 20 parts of Radix Rehmanniae Preparata, 12 parts of the Radix Paeoniae Albas, 20 parts of Radix Pseudostellariaes, 10 parts of Semen Plantaginiss, 12 parts of Semen Cuscutae, 9 parts of Fructus Lycii, 7 parts of Herba Epimedii, 8 parts of Fructus Rubies, 10 parts of Fructus Corni, 9 parts of Radix Polygoni Multiflori, 12 parts of Cornu Cervi Degelatinatums, 25 parts of Radix Asparagis, 10 parts of Fructus Forsythiaes.
Radix Angelicae Sinensis: sweet in the mouth, warm in nature, for enriching blood, emmenagogue.There is promoting blood flow to regulate menstruation, moisturize laxation, effect of the pain relieving of enriching blood, for menoxenia, dysmenorrhea, all diseases of blood deficiency.
Radix Rehmanniae Preparata: sweet in the mouth, slightly warm in nature.The yin nourishing of enriching blood, effect of life essence-filling, marrow-benefitting, for menoxenia, all diseases of blood deficiency, the hepatic and renal YIN deficiency.
The Radix Paeoniae Alba: bitter in the mouth, acid, cold nature.Radix Paeoniae Alba is made with yellow wine, has nourishing blood to suppress the hyperactive liver, slow middle pain relieving, and yin fluid astringing is received effect of antiperspirant, for menoxenia, the disease of the deficiency of YIN.
Radix Pseudostellariae: sweet in the mouth, bitter in the mouth, property is flat.There is replenishing QI to invigorate the spleen, effect of promoting the production of body fluid for nourishing the lung, tired for insufficiency of the spleen body, inappetence, weak after being ill, deficiency of both vital energy and Yin.
Semen Plantaginis: sweet in the mouth, cold nature.There is clearing away heat and promoting diuresis, effect that eliminating dampness by diuresis is treating stranguria, for edema distension, the puckery pain of pyretic stranguria.
Semen Cuscutae: sweet in the mouth, warm in nature.There is nourishing the liver and kidney, antiabortive, effect of improving eyesight, for vaginal bleeding due to deficiency of the kidney during pregnancy, the diseases such as frequent fetal movement.
Fructus Lycii: sweet in the mouth, property is flat.Have nourishing the liver and kidney, effect of replenishing vital essence to improve eyesight, for asthenia damage of essence, soreness of waist and knee joint, blood deficiency and yellow complexion.
Herba Epimedii: acrid in the mouth, sweet, warm in nature, there is kidney-replenishing, bone and muscle strengthening, effect of wind-damp dispelling, soft for muscles and bones flaccidity, numb overcautious, rheumatic arthralgia.
Fructus Rubi: sweet in the mouth, property is flat.There is effect of invigorating the liver and kidney, supporing yang, improving eyesight.
Fructus Corni: sour in the mouth, slightly warm in nature.Have liver and kidney tonifying, restrain astringent or styptic treatment for spontaneous sweating, controlling nocturnal emission with astringent drugs reducing urination, effect of pain relieving, for soreness of the waist and knees, menoxenia.
Radix Polygoni Multiflori: sweet in the mouth, warm in nature.Radix Polygoni Multiflori Preparata forms with decoction of black soybean Preparation process, has invigorating the liver and kidney, benefiting essence-blood, and effect of bone and muscle strengthening, for blood deficiency and yellow complexion, soreness of the waist and knees.
Cornu Cervi Degelatinatum: salty in the mouth, warm in nature.There is warming the kidney to activate YANG, anastaltic effect, for skin deficiency of the kidney yin, enuresis frequent micturition.
Radix Asparagi: sweet in the mouth, hardship, cold in nature.There is nourishing YIN to relieve dryness, effect that lung heat clearing is promoted the production of body fluid, for dryness of the lung dry cough, dry throat and mouth, dryness of the intestine constipation.
Fructus Forsythiae: bitter in the mouth, cold nature.Have heat-clearing and toxic substances removing, effect of dispersing swelling and dissipating binds, for epidemic febrile disease from the beginning of, warm joining the army.
The principle of Chinese medicinal formulae of the present invention based on Chinese medicine menoxenia barrenness, cures the disease to mend.That in prescription, selects is medical material of nourishing warm in nature, can not damage function of human body, in treatment menoxenia barrenness, can also reach strong health, improves the effect of immunity.
The specific embodiment
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1
6 grams of Radix Angelicae Sinensis, 10 grams of Radix Rehmanniae Preparata, 10 grams of the Radix Paeoniae Albas, 10 grams of Radix Pseudostellariaes, 6 grams of Semen Plantaginiss, 9 grams of Semen Cuscutae, 6 grams of Fructus Lycii, 3 grams of Herba Epimedii, 5 grams of Fructus Rubies, 6 grams of Fructus Corni, 6 grams of Radix Polygoni Multiflori, 9 grams of Cornu Cervi Degelatinatums, 15 grams of Radix Asparagis, 6 grams of Fructus Forsythiaes;
1. the Radix Paeoniae Alba is mixed thoroughly with appropriate yellow wine sprinkle, be then placed in pot fried dry, obtain Radix Paeoniae Alba, dry in the air cool for subsequent use;
2. Radix Polygoni Multiflori is mixed thoroughly with decoction of black soybean, put in the appropriate vessel of non iron, stew or steam to juice and exhaust, inside and outside while being all sepia, the air dry of drying in the air is dry, obtains Radix Polygoni Multiflori Preparata for subsequent use;
3. Cornu Cervi Degelatinatum is placed in to intense fire in marmite and is fried open, turn 20 minutes at a simmer, then put into Radix Angelicae Sinensis, Radix Rehmanniae Preparata, 12 parts of Radix Paeoniae Alba, Radix Pseudostellariae, Semen Plantaginis, Semen Cuscutae, Fructus Lycii, Herba Epimedii, Fructus Rubi, Fructus Corni, Radix Polygoni Multiflori Preparata, Radix Asparagi, Fructus Forsythiae intense fire is fried open, and turns 15 minutes at a simmer, leaches medicinal liquid;
4. recrement is watered intense fire again and is fried open, and turns 15 minutes at a simmer, and twice medicinal liquid mixes.
embodiment 2
8 grams of Radix Angelicae Sinensis, 15 grams of Radix Rehmanniae Preparata, 11 grams of the Radix Paeoniae Albas, 15 grams of Radix Pseudostellariaes, 8 grams of Semen Plantaginiss, 10 grams of Semen Cuscutae, 8 grams of Fructus Lycii, 5 grams of Herba Epimedii, 7 grams of Fructus Rubies, 8 grams of Fructus Corni, 8 grams of Radix Polygoni Multiflori, 10 grams of Cornu Cervi Degelatinatums, 20 grams of Radix Asparagis, 8 grams of Fructus Forsythiaes;
1. the Radix Paeoniae Alba is mixed thoroughly with appropriate yellow wine sprinkle, be then placed in pot fried dry, obtain Radix Paeoniae Alba, dry in the air cool for subsequent use;
2. Radix Polygoni Multiflori is mixed thoroughly with decoction of black soybean, put in the appropriate vessel of non iron, stew or steam to juice and exhaust, inside and outside while being all sepia, the air dry of drying in the air is dry, obtains Radix Polygoni Multiflori Preparata for subsequent use;
3. Cornu Cervi Degelatinatum is placed in to intense fire in marmite and is fried open, turn 25 minutes at a simmer, then put into Radix Angelicae Sinensis, Radix Rehmanniae Preparata, 12 parts of Radix Paeoniae Alba, Radix Pseudostellariae, Semen Plantaginis, Semen Cuscutae, Fructus Lycii, Herba Epimedii, Fructus Rubi, Fructus Corni, Radix Polygoni Multiflori Preparata, Radix Asparagi, Fructus Forsythiae intense fire is fried open, and turns 20 minutes at a simmer, leaches medicinal liquid;
4. recrement is watered intense fire again and is fried open, and turns 18 minutes at a simmer, and twice medicinal liquid mixes.
embodiment 3
10 grams of Radix Angelicae Sinensis, 25 grams of Radix Rehmanniae Preparata, 14 grams of the Radix Paeoniae Albas, 25 grams of Radix Pseudostellariaes, 12 grams of Semen Plantaginiss, 14 grams of Semen Cuscutae, 10 grams of Fructus Lycii, 8 grams of Herba Epimedii, 9 grams of Fructus Rubies, 11 grams of Fructus Corni, 10 grams of Radix Polygoni Multiflori, 14 grams of Cornu Cervi Degelatinatums, 28 grams of Radix Asparagis, 12 grams of Fructus Forsythiaes;
1. the Radix Paeoniae Alba is mixed thoroughly with appropriate yellow wine sprinkle, be then placed in pot fried dry, obtain Radix Paeoniae Alba, dry in the air cool for subsequent use;
2. Radix Polygoni Multiflori is mixed thoroughly with decoction of black soybean, put in the appropriate vessel of non iron, stew or steam to juice and exhaust, inside and outside while being all sepia, the air dry of drying in the air is dry, obtains Radix Polygoni Multiflori Preparata for subsequent use;
3. Cornu Cervi Degelatinatum is placed in to intense fire in marmite and is fried open, turn 35 minutes at a simmer, then put into Radix Angelicae Sinensis, Radix Rehmanniae Preparata, 12 parts of Radix Paeoniae Alba, Radix Pseudostellariae, Semen Plantaginis, Semen Cuscutae, Fructus Lycii, Herba Epimedii, Fructus Rubi, Fructus Corni, Radix Polygoni Multiflori Preparata, Radix Asparagi, Fructus Forsythiae intense fire is fried open, and turns 35 minutes at a simmer, leaches medicinal liquid;
4. recrement is watered intense fire again and is fried open, and turns 25 minutes at a simmer, and twice medicinal liquid mixes.
embodiment 4
12 grams of Radix Angelicae Sinensis, 30 grams of Radix Rehmanniae Preparata, 15 grams of the Radix Paeoniae Albas, 30 grams of Radix Pseudostellariaes, 15 grams of Semen Plantaginiss, 15 grams of Semen Cuscutae, 12 grams of Fructus Lycii, 9 grams of Herba Epimedii, 10 grams of Fructus Rubies, 12 grams of Fructus Corni, 12 grams of Radix Polygoni Multiflori, 15 grams of Cornu Cervi Degelatinatums, 30 grams of Radix Asparagis, 15 grams of Fructus Forsythiaes;
1. the Radix Paeoniae Alba is mixed thoroughly with appropriate yellow wine sprinkle, be then placed in pot fried dry, obtain Radix Paeoniae Alba, dry in the air cool for subsequent use;
2. Radix Polygoni Multiflori is mixed thoroughly with decoction of black soybean, put in the appropriate vessel of non iron, stew or steam to juice and exhaust, inside and outside while being all sepia, the air dry of drying in the air is dry, obtains Radix Polygoni Multiflori Preparata for subsequent use;
3. Cornu Cervi Degelatinatum is placed in to intense fire in marmite and is fried open, turn 45 minutes at a simmer, then put into Radix Angelicae Sinensis, Radix Rehmanniae Preparata, 12 parts of Radix Paeoniae Alba, Radix Pseudostellariae, Semen Plantaginis, Semen Cuscutae, Fructus Lycii, Herba Epimedii, Fructus Rubi, Fructus Corni, Radix Polygoni Multiflori Preparata, Radix Asparagi, Fructus Forsythiae intense fire is fried open, and turns 40 minutes at a simmer, leaches medicinal liquid;
4. recrement is watered intense fire again and is fried open, and turns 30 minutes at a simmer, and twice medicinal liquid mixes.
embodiment 5
9 grams of Radix Angelicae Sinensis, 20 grams of Radix Rehmanniae Preparata, 12 grams of the Radix Paeoniae Albas, 20 grams of Radix Pseudostellariaes, 10 grams of Semen Plantaginiss, 12 grams of Semen Cuscutae, 9 grams of Fructus Lycii, 7 grams of Herba Epimedii, 8 grams of Fructus Rubies, 10 grams of Fructus Corni, 9 grams of Radix Polygoni Multiflori, 12 grams of Cornu Cervi Degelatinatums, 25 grams of Radix Asparagis, 10 grams of Fructus Forsythiaes;
1. the Radix Paeoniae Alba is mixed thoroughly with appropriate yellow wine sprinkle, be then placed in pot fried dry, obtain Radix Paeoniae Alba, dry in the air cool for subsequent use;
2. Radix Polygoni Multiflori is mixed thoroughly with decoction of black soybean, put in the appropriate vessel of non iron, stew or steam to juice and exhaust, inside and outside while being all sepia, the air dry of drying in the air is dry, obtains Radix Polygoni Multiflori Preparata for subsequent use;
3. Cornu Cervi Degelatinatum is placed in to intense fire in marmite and is fried open, turn 30 minutes at a simmer, then put into Radix Angelicae Sinensis, Radix Rehmanniae Preparata, 12 parts of Radix Paeoniae Alba, Radix Pseudostellariae, Semen Plantaginis, Semen Cuscutae, Fructus Lycii, Herba Epimedii, Fructus Rubi, Fructus Corni, Radix Polygoni Multiflori Preparata, Radix Asparagi, Fructus Forsythiae intense fire is fried open, and turns 25 minutes at a simmer, leaches medicinal liquid;
4. recrement is watered intense fire again and is fried open, and turns 20 minutes at a simmer, and twice medicinal liquid mixes;
Using method: for making the present invention reach optimum therapeuticing effect, Chinese medicine decoction of the present invention, every day twice, in sooner or later taking half an hour after meal, cut out menstrual period.
model case one
Liu XX, female, 35 years old, Liu Yu booth village, Sun Wu town, Huimin County, Accessories during Binzhou, Shandong Province.Symptom: patient, because of in bar work, lives irregular, the smoking that is on the drink, lethargy is tried out, and menoxenia, causes complexion dimness, and marry and within latter 4 years, all there is no pregnancy always, be menoxenia barrenness after diagnosing.Sick age: 4 years.Examine the time: on August 21st, 2010; Chinese medicinal formulae of the present invention, every day twice, in sooner or later taking half an hour after meal, cut out menstrual period, takes 1 month, and the mental status is clearly better; Take 2 months, complexion takes a turn for the better, and face starts ruddy; Take medicine after 3 months, menstrual blood volume is normal, and menstrual period are normal; Continue to take after 1 month, find conceivedly, drug withdrawal, gives birth to a healthy boy baby smoothly afterwards, has no adverse reaction during taking Chinese medicinal formulae of the present invention.
model case two
King XX, female, 28 years old, Boxing County, Accessories during Binzhou, Shandong Province.Symptom: patient never takes contraceptives after marrying for 24 years old, marries 4 years, but never conceived.Learn that through careful inquiry patient's menstruation is always very irregular, came menophania from 15 years old, annual menstruation only comes 5 to 7 times, come about 3 days, and amount is few, before and after menstrual period and also there is no obvious malaise symptoms menstrual period at every turn.By careful inspection, be diagnosed as menoxenia barrenness.Sick age: 6 years.Examine the time: on April 12nd, 2011; Chinese medicinal formulae of the present invention, every day twice, in sooner or later taking half an hour after meal, cut out menstrual period, takes 2 months, when menstrual period, continues 5 days, and menstrual blood volume is comparatively normal; Use 4 months, recover menstrual period normal; Continue decrement and consolidate use 1 month, every two days once, and in sooner or later taking half an hour after meal, cut out menstrual period, always normal through the phase after drug withdrawal.Patient was in drug withdrawal after 2 months, conceived smoothly afterwards.
In order to verify the effect of Chinese medicinal formulae of the present invention, we have carried out the experiment (embodiment 5) of medicine, and accurately data have been carried out to statistics and mathematical analysis.Specific experiment result is as following table:
Figure 691795DEST_PATH_IMAGE001
Chinese medicinal formulae treatment menoxenia barrenness effect of the present invention is remarkable.Prove through clinical trial, total effective rate is 97%, cure rate is 85%, improve 17% than matched group Western medicine regulating menstruation class Drug therapy effective percentage, cure rate is high by 35%, and simple to operate, cheap, relapse rate is extremely low, the fundamentally uncomfortable symptom of regulating menstruation, and can in curing the disease, nurse one's health health, increase autoimmunity, removing menoxenia barrenness patient's slight illness, is the comparatively desirable medicine for the treatment of menoxenia barrenness, is also the optimal path that causes infertile patient and seek to resolve safely infertile worry because of menoxenia barrenness.

Claims (9)

1. a preparation method for the treatment of the Chinese medicinal formulae of menoxenia barrenness, is characterized in that, takes off the primary raw material of stating weight proportion: Radix Angelicae Sinensis 6-12 part, Radix Rehmanniae Preparata 10-30 part, Radix Paeoniae Alba 10-15 part, Radix Pseudostellariae 10-30 part, Semen Plantaginis 6-15 part, Semen Cuscutae 9-15 part, Fructus Lycii 6-12 part, Herba Epimedii 3-9 part, Fructus Rubi 5-10 part, Fructus Corni 6-12 part, Radix Polygoni Multiflori 6-12 part, Cornu Cervi Degelatinatum 9-15 part, Radix Asparagi 15-30 part, Fructus Forsythiae 6-15 part; Step is as follows:
1. the Radix Paeoniae Alba is mixed thoroughly with appropriate yellow wine sprinkle, be then placed in pot fried dry, obtain Radix Paeoniae Alba, dry in the air cool for subsequent use;
2. Radix Polygoni Multiflori is mixed thoroughly with decoction of black soybean, put in the appropriate vessel of non iron, stew or steam to juice and exhaust, inside and outside while being all sepia, the air dry of drying in the air is dry, obtains Radix Polygoni Multiflori Preparata for subsequent use;
3. Cornu Cervi Degelatinatum is placed in to intense fire in marmite and is fried open, turn 20-45 minute at a simmer, then put into Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Radix Paeoniae Alba, Radix Pseudostellariae, Semen Plantaginis, Semen Cuscutae, Fructus Lycii, Herba Epimedii, Fructus Rubi, Fructus Corni, Radix Polygoni Multiflori Preparata, Radix Asparagi, Fructus Forsythiae intense fire is fried open, and turns 15-40 minute at a simmer, leaches medicinal liquid;
4. recrement is watered intense fire again and is fried open, and turns 15-30 minute at a simmer, and twice medicinal liquid mixes.
2. preparation method according to claim 1, is characterized in that, each crude drug is as follows: Radix Angelicae Sinensis 8-10 part, Radix Rehmanniae Preparata 15-25 part, Radix Paeoniae Alba 11-14 part, Radix Pseudostellariae 15-25 part, Semen Plantaginis 8-12 part, Semen Cuscutae 10-14 part, Fructus Lycii 8-10 part, Herba Epimedii 5-8 part, Fructus Rubi 7-9 part, Fructus Corni 8-11 part, Radix Polygoni Multiflori 8-10 part, Cornu Cervi Degelatinatum 10-14 part, Radix Asparagi 20-28 part, Fructus Forsythiae 8-12 part.
3. preparation method according to claim 1, is characterized in that, each crude drug is as follows: 9 parts of Radix Angelicae Sinensis, 20 parts of Radix Rehmanniae Preparata, 12 parts of the Radix Paeoniae Albas, 20 parts of Radix Pseudostellariaes, 10 parts of Semen Plantaginiss, 12 parts of Semen Cuscutae, 9 parts of Fructus Lycii, 7 parts of Herba Epimedii, 8 parts of Fructus Rubies, 10 parts of Fructus Corni, 9 parts of Radix Polygoni Multiflori, 12 parts of Cornu Cervi Degelatinatums, 25 parts of Radix Asparagis, 10 parts of Fructus Forsythiaes.
4. preparation method according to claim 1, is characterized in that, 3. step is placed in Cornu Cervi Degelatinatum intense fire in marmite and is fried open, and turns 25-35 minute at a simmer.
5. preparation method according to claim 4, is characterized in that, 3. step is placed in Cornu Cervi Degelatinatum intense fire in marmite and is fried open, and turns 30 minutes at a simmer.
6. preparation method according to claim 1, is characterized in that, 3. step turns 20-35 minute at a simmer, leaches medicinal liquid.
7. preparation method according to claim 6, is characterized in that, 3. step turns 25 minutes at a simmer, leaches medicinal liquid.
8. preparation method according to claim 1, is characterized in that, 4. step turns 18-25 minute at a simmer, and twice medicinal liquid mixes.
9. preparation method according to claim 8, is characterized in that, 4. step turns 20 minutes at a simmer, and twice medicinal liquid mixes.
CN201310017193.7A 2013-01-17 2013-01-17 Chinese medicinal formula for treating menstrual disorder type infertility and preparation method thereof Expired - Fee Related CN103110798B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310017193.7A CN103110798B (en) 2013-01-17 2013-01-17 Chinese medicinal formula for treating menstrual disorder type infertility and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201310017193.7A CN103110798B (en) 2013-01-17 2013-01-17 Chinese medicinal formula for treating menstrual disorder type infertility and preparation method thereof

Publications (2)

Publication Number Publication Date
CN103110798A CN103110798A (en) 2013-05-22
CN103110798B true CN103110798B (en) 2014-06-25

Family

ID=48409204

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201310017193.7A Expired - Fee Related CN103110798B (en) 2013-01-17 2013-01-17 Chinese medicinal formula for treating menstrual disorder type infertility and preparation method thereof

Country Status (1)

Country Link
CN (1) CN103110798B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104873682A (en) * 2015-05-11 2015-09-02 臧海阳 Traditional Chinese medicine composition for treating internal phlegm-dampness retention irregular menstruation and preparation method of traditional Chinese medicine composition
CN114522342A (en) * 2022-01-12 2022-05-24 上海中医药大学附属岳阳中西医结合医院 Wearable acupuncture point therapeutic apparatus for relieving or treating infertility

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1279090A (en) * 1999-06-25 2001-01-10 刘永香 Powdered medicine for conditioning viscera and whole body
CN1319414A (en) * 2001-01-19 2001-10-31 刘军 Medicine for treating hecrosis of femoral head
CN102274454A (en) * 2011-07-14 2011-12-14 必恒必信(北京)投资管理有限公司 Lady health-care wine and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1279090A (en) * 1999-06-25 2001-01-10 刘永香 Powdered medicine for conditioning viscera and whole body
CN1319414A (en) * 2001-01-19 2001-10-31 刘军 Medicine for treating hecrosis of femoral head
CN102274454A (en) * 2011-07-14 2011-12-14 必恒必信(北京)投资管理有限公司 Lady health-care wine and preparation method thereof

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
丁爱国等.补肾活血法的临床应用及实验研究概述.《山东中医杂志》.1994,第13卷(第8期),382-384. *
中西医治疗女性不孕症113例体会;王艳玲;《黔南民族医专学报》;19980630;第12卷(第2期);69-70 *
五子衍宗丸加减治疗黄体功能不健性不孕;范栋贤;《河南中医》;20031031;第23卷(第10期);77 *
徐晓洁等.黄体功能不全性不孕不育症中西医研究进展.《中医药临床杂志》.2006,第18卷(第1期),97-100.
王艳玲.中西医治疗女性不孕症113例体会.《黔南民族医专学报》.1998,第12卷(第2期),69-70.
范栋贤.五子衍宗丸加减治疗黄体功能不健性不孕.《河南中医》.2003,第23卷(第10期),77.
黄体功能不全性不孕不育症中西医研究进展;徐晓洁等;《中医药临床杂志》;20060228;第18卷(第1期);97-100 *

Also Published As

Publication number Publication date
CN103110798A (en) 2013-05-22

Similar Documents

Publication Publication Date Title
CN102166317B (en) Traditional Chinese medicine combination for curing metrorrhagia and metrostaxis
CN101912585B (en) Medicament for treating myoma of uterus and preparation method thereof
CN103071023B (en) Traditional Chinese medicinal composition for effectively treating diabetes
CN103705866A (en) Traditional Chinese medicine composition for treating hypomenorrhea
CN106267120A (en) A kind of Chinese medicine for treating rhinitis preparation and preparation method thereof
CN104208554A (en) Traditional Chinese medicine mainly for treating multiple female diseases
CN101912551B (en) Miscarriage-prevention Chinese medicinal composition
CN104043022A (en) Traditional Chinese medicine composition for treating gynecologic inflammation
CN103393989A (en) Traditional Chinese medicine composition for treating gynecologic inflammation
CN103055042B (en) Chinese medicinal herb composition for treating habitual abortion and preparation method thereof
CN103110798B (en) Chinese medicinal formula for treating menstrual disorder type infertility and preparation method thereof
CN103272189B (en) Medicine for curing gallstones
CN103611138B (en) Uterine-warming and pregnancy-promoting pill
CN102274445A (en) Cassia twig common burreed rhizome tumor eliminating pills
CN102068668A (en) Chinese medicinal composition for treating hypochondriac pain
CN101700389A (en) Traditional Chinese medicine composite for curing rheumatism and rheumatoid diseases
CN104127561A (en) Traditional Chinese medicine for treatment of infertility gynecological disease
CN108969745A (en) A kind of moon conditioned navel paster
CN106110207A (en) A kind of Chinese medicine composition for infertility
CN101085140A (en) Medicine for treating preceded menstrual cycle
CN103055043A (en) Traditional Chinese medicine preparation for activating ovarian function and preparation method thereof
CN103071017A (en) Traditional Chinese medicine composition for treating infantile uterus and preparation method of same
CN104069463A (en) Traditional Chinese medicinal medicament for treating gynaecological metrorrhagia and metrostaxis
CN105169189A (en) Medicament for treating hypothyroidism
CN104274809A (en) Traditional Chinese medicine composition for treating menstrual headache and preparation method of traditional Chinese medicine composition

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
ASS Succession or assignment of patent right

Owner name: CHEN XICHENG

Free format text: FORMER OWNER: WANG LIYUN

Effective date: 20140516

C41 Transfer of patent application or patent right or utility model
C53 Correction of patent of invention or patent application
CB03 Change of inventor or designer information

Inventor after: Chen Fang

Inventor after: Yu Jianmin

Inventor before: Wang Libin

Inventor before: Wang Yanju

COR Change of bibliographic data

Free format text: CORRECT: INVENTOR; FROM: WANG LIYUN WANG YANJU TO: CHEN FANG YU JIANMIN

Free format text: CORRECT: ADDRESS; FROM: 252400 LIAOCHENG, SHANDONG PROVINCE TO: 250014 JINAN, SHANDONG PROVINCE

TA01 Transfer of patent application right

Effective date of registration: 20140516

Address after: 250014 Shandong Province, Lixia District of Ji'nan city jiangshuiquan Road No. 1 jichai nine dormitory 2 floor 1 unit 201

Applicant after: Chen Xicheng

Address before: 252400 No. 28 Xinxing street, Shandong, Shenxian

Applicant before: Wang Libin

C14 Grant of patent or utility model
GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: HAIMEN JIANGHAI CONSTRUCTION INVESTMENT CO., LTD.

Free format text: FORMER OWNER: CHEN XICHENG

Effective date: 20141105

C41 Transfer of patent application or patent right or utility model
COR Change of bibliographic data

Free format text: CORRECT: ADDRESS; FROM: 250014 JINAN, SHANDONG PROVINCE TO: 226100 NANTONG, JIANGSU PROVINCE

TR01 Transfer of patent right

Effective date of registration: 20141105

Address after: 226100, 999, Guangzhou Road, Haimen, Jiangsu, Nantong

Patentee after: Haimen Jianghai Construction Investment Co.,Ltd.

Address before: 250014 Shandong Province, Lixia District of Ji'nan city jiangshuiquan Road No. 1 jichai nine dormitory 2 floor 1 unit 201

Patentee before: Chen Xicheng

CB03 Change of inventor or designer information
CB03 Change of inventor or designer information

Inventor after: Ran Hongtu

Inventor after: Yu Jianmin

Inventor before: Chen Fang

Inventor before: Yu Jianmin

TR01 Transfer of patent right
TR01 Transfer of patent right

Effective date of registration: 20170815

Address after: Zheng Jie 400050 Xiejiawan Jiulongpo District of Chongqing City No. 95 Building 2 unit 3 1-3

Patentee after: Ran Hongtu

Address before: 312365 Zhejiang Province, Shaoxing city Shangyu District Songxia Town City Station International Plaza building 36 unit room 1-101

Patentee before: ZHEJIANG HONGSHENG TECHNOLOGY TRANSFER SERVICES CO.,LTD.

Effective date of registration: 20170815

Address after: 312365 Zhejiang Province, Shaoxing city Shangyu District Songxia Town City Station International Plaza building 36 unit room 1-101

Patentee after: ZHEJIANG HONGSHENG TECHNOLOGY TRANSFER SERVICES CO.,LTD.

Address before: 226100, 999, Guangzhou Road, Haimen, Jiangsu, Nantong

Patentee before: Haimen Jianghai Construction Investment Co.,Ltd.

CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20140625

Termination date: 20190117

CF01 Termination of patent right due to non-payment of annual fee