CN105535719A - Medicine composition for treating blood stasis type amenorrhoea - Google Patents
Medicine composition for treating blood stasis type amenorrhoea Download PDFInfo
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Abstract
The invention discloses a medicine composition for treating blood stasis type amenorrhoea and belongs to the field of traditional Chinese medicines. The medicine composition is prepared from salvia miltiorrhiza, red-rooted salvia roots, prepared rehmannia roots, prepared fleece-flower roots, schisandra chinensis, astragalus roots, motherwort, eucommia barks and medicinal indianmulberry roots. The medicine composition has the remarkable effects of tonifying kidney, warming yang, nourishing yin and blood, promoting blood circulation to remove blood stasis, promoting the circulation of qi and promoting menstruation and can effectively cure the amenorrhea, especially the blood stasis type amenorrhoea. Clinical application verifies that the medicine composition is definite in treating effect, mild in medicine property, free of toxic and side effects and adverse reactions, high in safety coefficient and low in recurrence rate, the total effective rate of clinical observation is 95%, and the medicine composition can serve as a clinical effective medicine to be popularized and applied.
Description
Technical field
The invention belongs to technical field of Chinese medicines, relate to a kind of pharmaceutical composition, particularly a kind of pharmaceutical composition for the treatment of blood stasis type menostasis and preparation method thereof.
Background technology
Amenorrhea is symptom more common in clinical gynaecopathia, can be caused by various different reason, is usually divided into primary amenorrhea and secondary amenorrhea two kinds.Wherein there is menolipsis more than 6 months persons in secondary amenorrhea after referring to menstrual onset, or menolipsis reaches 3 normal gap periods persons in the women of hypomenorrhea.Modern medicine study point out secondary amenorrhea mainly due to systemic disease and other stimulate or hypothalamus, hypophysis cerebri disease cause, when there is secondary amenorrhea, normal with spirit depressing, irritable, soreness of the waist and knees, dizziness and tinnitus, shortness of breath and palpitation, the symptom such as weak, not only causes the serious misery of patient's body and mind aspect, and easily cause occurring the serious symptoms such as infertile have the patient of fertility demand to cause obvious impact to part.
Traditional western medical treatment amenorrhea adopts hormone mimics menstrual cycle Hormone change, impels menstruation to be formed.But side effect is more, easily recur after drug withdrawal, potential risk is large.The traditional Chinese medical science is said without secondary amenorrhea one, is directly classified as " amenorrhea " category, and tcm clinical practice thinks that secondary amenorrhea deficiency and excess all has, and empty person is in the majority, mainly because of the congenital deficiency of kidney qi and the day after tomorrow loss caused by; Reality person is mainly because of caused by the tired stagnation of QI of blood; The two is held concurrently mutually as the card that the empty stasis of blood is mixed appears in disease.The traditional Chinese medical science has long experience in treatment amenorrhea, and treating both the principal and secondary aspects of a disease, toxic and side effects is little, has the advantage that western medicine can not be compared, and therefore increasing patient selects Chinese medicine sick to treat this.
Summary of the invention
In order to make up the deficiencies in the prior art, the present invention on the basis of ancestral side, through improvement, checking, for blood stasis type menostasis patient provide a kind of evident in efficacy, short treating period, healing after the pharmaceutical composition for the treatment of blood stasis type menostasis that not easily recurs.
For realizing object of the present invention, the technical solution used in the present invention is as follows:
Treat a pharmaceutical composition for blood stasis type menostasis, be prepared from by following Chinese crude drug: Radix Salviae Miltiorrhizae, Rhizoma Sparganii, Radix Rehmanniae Preparata, Radix Polygoni Multiflori Preparata, Fructus Schisandrae Chinensis, the Radix Astragali, Herba Leonuri, the Cortex Eucommiae, Radix Morindae Officinalis.
Preferably, the present invention treats the pharmaceutical composition of blood stasis type menostasis, is prepared from by the Chinese crude drug of following weight portion:
Radix Salviae Miltiorrhizae 12-16, Rhizoma Sparganii 8-12, Radix Rehmanniae Preparata 16-22, Radix Polygoni Multiflori Preparata 6-10, Fructus Schisandrae Chinensis 8-12, Radix Astragali 12-16, Herba Leonuri 8-12, Cortex Eucommiae 6-10, Radix Morindae Officinalis 10-14.
Further preferably, the present invention treats the pharmaceutical composition of blood stasis type menostasis, is prepared from by the Chinese crude drug of following weight portion: Radix Salviae Miltiorrhizae 14, Rhizoma Sparganii 10, Radix Rehmanniae Preparata 19, Radix Polygoni Multiflori Preparata 8, Fructus Schisandrae Chinensis 10, the Radix Astragali 14, Herba Leonuri 10, the Cortex Eucommiae 8, Radix Morindae Officinalis 12.
Preferably, described pharmaceutical composition is prepared into oral formulations.
It is further preferred that described oral formulations is tablet, capsule, granule or oral liquid.
In side of the present invention, Radix Salviae Miltiorrhizae: [nature and flavor] are bitter, are slightly cold.[return through] GUIXIN, Liver Channel.[function cures mainly] stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.For menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Rhizoma Sparganii: [nature and flavor] toil is flat.[return through] enters liver.Spleen channel.[function cures mainly] removing blood stasis, circulation of qi promoting, removing food stagnancy, pain relieving.Zhi lumps in the chest and abdomen, coagulation of QI-blood, trusted subordinate's pain, the lower swollen pain of the side of body, amenorrhea, postnatal blood stasis is suffered from abdominal pain, traumatic injury.Skin ulcer swells hard.
Radix Rehmanniae Preparata: [nature and flavor] are sweet, tepor.[return through] returns liver, kidney channel.[function cures mainly] nourishing YIN and supplementing blood, beneficial essence fills out marrow.For the hepatic and renal YIN deficiency, soreness of the waist and knees, osteopyrexia and fever, night sweat is passed out semen, and interior-heat is quenched one's thirst, blood deficiency and yellow complexion, severe palpitation, menoxenia, and metrostaxis is dizzy, tinnitus, early whitening of beard and hair.
Radix Polygoni Multiflori Preparata: [nature and flavor] are bitter, sweet, puckery, temperature.[return through] returns liver, the heart, kidney channel.[function cures mainly] invigorating the liver and kidney, benefiting essence-blood, black beard and hair, bone and muscle strengthening.For blood deficiency and yellow complexion, vertigo and tinnitus, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, bleeding not during menses, chronic malaria body is empty; Hyperlipidemia.
Fructus Schisandrae Chinensis: [nature and flavor] are sour, sweet, temperature.[return through] returns lung, the heart, kidney channel.[function cures mainly] restrains astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
The Radix Astragali: [nature and flavor] are sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Herba Leonuri: [nature and flavor] are bitter, pungent, are slightly cold.[return through] returns liver, pericardium channel.[function cures mainly] promoting blood flow to regulate menstruation, inducing diuresis to remove edema.For menoxenia, dysmenorrhea, amenorrhea, lochiorrhea, edema oliguria; Acute nephritis edema.
The Cortex Eucommiae, [nature and flavor] are sweet, temperature.[return through] returns liver, kidney channel.[function cures mainly] invigorating the liver and kidney, bone and muscle strengthening, antiabortive.For lumbago due to renal deficiency, muscles and bones is unable, blood leaking in gestation, frequent fetal movement; Hypertension.
Radix Morindae Officinalis, [nature and flavor] are sweet, pungent, tepor.[return through] returns kidney, Liver Channel.[function cures mainly] kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For impotence and seminal emission, cold womb is infertile, menoxenia, and few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity is soft.
Pharmaceutical composition of the present invention mainly according to the pathogenic characteristic prescription compatibility of blood stasis type menostasis, Radix Salviae Miltiorrhizae in side, Rhizoma Sparganii, Herba Leonuri, promoting blood circulation by removing blood stasis, inducing menstruation to relieve menalgia; Radix Rehmanniae Preparata, Radix Polygoni Multiflori Preparata, nourishing YIN and supplementing blood; Fructus Schisandrae Chinensis, the Radix Astragali, invigorating QI to consolidate the body surface resistance, supplementing QI for promoting the production of body fluid; The Cortex Eucommiae, Radix Morindae Officinalis, the liver and the kidney tonifying, warming YANG damp eliminating.All medicines share, and play the kidney invigorating warming YANG altogether, nourishing YIN and supplementing blood, blood circulation promoting and blood stasis dispelling, the effect of promote qi circulation opening warp, effectively can cure amenorrhea particularly blood stasis type menostasis.Verify through clinical practice, its determined curative effect, mild in medicine property and, do not occur toxic and side effects and untoward reaction, safety coefficient is high, and relapse rate is low, clinical observation total effective rate more than 95%, can be used as clinical active drug to apply, and arbitrarily change formula and proportioning, therapeutic effect of the present invention can not be reached completely.
Present invention also offers the preparation method of described pharmaceutical composition, it is characterized in that comprising following steps:
Take the Radix Salviae Miltiorrhizae of recipe quantity, Rhizoma Sparganii, Radix Rehmanniae Preparata, Radix Polygoni Multiflori Preparata, Fructus Schisandrae Chinensis, the Radix Astragali, Herba Leonuri, the Cortex Eucommiae, Radix Morindae Officinalis, put into Chinese medicine grinder respectively and pulverize, cross 40 mesh sieves after pulverizing, mix homogeneously; Add decoction pot, decoct with water twice, add water 6-8 times amount for the first time, and warm macerating 4 hours decocts 3h, and second time amount of water is 4-6 times amount, and decocting time is 1.5h, merges decoction liquor, filters, obtains filtrate; Concentrating under reduced pressure filtrate, dry, put into Chinese medicine grinder and pulverize, after pulverizing, cross 80 mesh sieves; Add pharmaceutically acceptable carrier and be prepared into tablet, capsule, granule or oral liquid.
Detailed description of the invention
Below by way of the description of detailed description of the invention, the invention will be further described, but this is not limitation of the present invention, those skilled in the art are according to basic thought of the present invention, various amendment or improvement can be made, but only otherwise depart from basic thought of the present invention, all within the scope of the present invention.
The preparation of EXAMPLE l capsule
The each raw material of the present invention is taken: Radix Salviae Miltiorrhizae 14, Rhizoma Sparganii 10, Radix Rehmanniae Preparata 19, Radix Polygoni Multiflori Preparata 8, Fructus Schisandrae Chinensis 10, the Radix Astragali 14, Herba Leonuri 10, the Cortex Eucommiae 8, Radix Morindae Officinalis 12 by following weight portion.
Preparation method:
Take the Radix Salviae Miltiorrhizae of recipe quantity, Rhizoma Sparganii, Radix Rehmanniae Preparata, Radix Polygoni Multiflori Preparata, Fructus Schisandrae Chinensis, the Radix Astragali, Herba Leonuri, the Cortex Eucommiae, Radix Morindae Officinalis, put into Chinese medicine grinder respectively and pulverize, cross 40 mesh sieves after pulverizing, mix homogeneously; Add decoction pot, decoct with water twice, add water 6 times amount for the first time, and warm macerating 4 hours decocts 3h, and second time amount of water is 4 times amount, and decocting time is 1.5h, merges decoction liquor, filters, obtains filtrate; Concentrating under reduced pressure filtrate, dry, put into Chinese medicine grinder and pulverize, after pulverizing, cross 80 mesh sieves; Add pharmaceutically acceptable carrier, mix homogeneously, fill capsule, is prepared into capsule, and every containing crude drug 0.4g.
The preparation of embodiment 2 tablet
The each raw material of the present invention is taken: Radix Salviae Miltiorrhizae 14, Rhizoma Sparganii 10, Radix Rehmanniae Preparata 19, Radix Polygoni Multiflori Preparata 8, Fructus Schisandrae Chinensis 10, the Radix Astragali 14, Herba Leonuri 10, the Cortex Eucommiae 8, Radix Morindae Officinalis 12 by following weight portion.
Preparation method:
Take the Radix Salviae Miltiorrhizae of recipe quantity, Rhizoma Sparganii, Radix Rehmanniae Preparata, Radix Polygoni Multiflori Preparata, Fructus Schisandrae Chinensis, the Radix Astragali, Herba Leonuri, the Cortex Eucommiae, Radix Morindae Officinalis, put into Chinese medicine grinder respectively and pulverize, cross 40 mesh sieves after pulverizing, mix homogeneously; Add decoction pot, decoct with water twice, add water 8 times amount for the first time, and warm macerating 4 hours decocts 3h, and second time amount of water is 6 times amount, and decocting time is 1.5h, merges decoction liquor, filters, obtains filtrate; Concentrating under reduced pressure filtrate, dry, put into Chinese medicine grinder and pulverize, after pulverizing, cross 80 mesh sieves; Add pharmaceutically acceptable carrier, mix homogeneously, tabletting, be prepared into tablet, every sheet is containing crude drug 0.4g.
The preparation of embodiment 3 granule
The each raw material of the present invention is taken: Radix Salviae Miltiorrhizae 14, Rhizoma Sparganii 10, Radix Rehmanniae Preparata 19, Radix Polygoni Multiflori Preparata 8, Fructus Schisandrae Chinensis 10, the Radix Astragali 14, Herba Leonuri 10, the Cortex Eucommiae 8, Radix Morindae Officinalis 12 by following weight portion.
Preparation method:
Take the Radix Salviae Miltiorrhizae of recipe quantity, Rhizoma Sparganii, Radix Rehmanniae Preparata, Radix Polygoni Multiflori Preparata, Fructus Schisandrae Chinensis, the Radix Astragali, Herba Leonuri, the Cortex Eucommiae, Radix Morindae Officinalis, put into Chinese medicine grinder respectively and pulverize, cross 40 mesh sieves after pulverizing, mix homogeneously; Add decoction pot, decoct with water twice, add water 7 times amount for the first time, and warm macerating 4 hours decocts 3h, and second time amount of water is 5 times amount, and decocting time is 1.5h, merges decoction liquor, filters, obtains filtrate; Concentrating under reduced pressure filtrate, dry, put into Chinese medicine grinder and pulverize, after pulverizing, cross 80 mesh sieves; Add pharmaceutically acceptable carrier, mix homogeneously, add pharmaceutically acceptable carrier, be prepared into granule, pack, every bag containing crude drug 2.0g.
The preparation of embodiment 4 granule
The each raw material of the present invention is taken: Radix Salviae Miltiorrhizae 16, Rhizoma Sparganii 12, Radix Rehmanniae Preparata 22, Radix Polygoni Multiflori Preparata 10, Fructus Schisandrae Chinensis 12, the Radix Astragali 16, Herba Leonuri 12, the Cortex Eucommiae 10, Radix Morindae Officinalis 14 by following weight portion.
Preparation method is with embodiment 3.
The preparation of embodiment 5 granule
The each raw material of the present invention is taken: Radix Salviae Miltiorrhizae 12, Rhizoma Sparganii 8, Radix Rehmanniae Preparata 16, Radix Polygoni Multiflori Preparata 6, Fructus Schisandrae Chinensis 8, the Radix Astragali 12, Herba Leonuri 8, the Cortex Eucommiae 6, Radix Morindae Officinalis 10 by following weight portion.
Preparation method is with embodiment 3.
The preparation of embodiment 6 granule
The each raw material of the present invention is taken: Radix Salviae Miltiorrhizae 20, Rhizoma Sparganii 15, Radix Rehmanniae Preparata 10, Fructus Schisandrae Chinensis 15, the Radix Astragali 10, the Cortex Eucommiae 5, Radix Morindae Officinalis 6 by following weight portion.
Preparation method is with embodiment 3.
The clinical observation of embodiment 7 Chinese medicine preparation treatment of the present invention blood stasis type menostasis
1 clinical data and diagnostic criteria
1.1 clinical datas:
Physical data: amenorrhea patients totally 180 examples choosing hospital admission in May ,-2013 in May, 2012.Wherein outpatient service 111 example, ward 69 example, age 20-40 year, 29.2 years old mean age, all cases previously all has normal menstrual cycle, more than rear menolipsis equal 6 cycles, the course of disease 6 months-3 years, average course of disease 15 months.According to the principle of parallel control, be divided into contrast one group, contrast two groups and treatment group, each 60 examples, the age, the course of disease etc. of three groups of group patients, without significant difference, have comparability.
1.2 diagnostic criterias:
Western medicine diagnose standard is with reference to " the amenorrhea diagnoses and treatment guide " of department of obstetrics and gynecology branch of Chinese Medical Association endocrinology group formulation in 2011.
Tcm diagnosis CM syndrome differentiation criterion adopts the diagnostic criteria of " tcm symptom Differential Diagnosis " blood stasis type menostasis, intends the symptom standard of blood stasis type menostasis disease: the menstruation several months is obstructed, spirit depressing, irritable, dizziness headache, hypochondriac pain uncomfortable in chest, distending pain of the breast, lower abdominal distention pain or tenderness.Body of the tongue purple is dim or have petechia, deep and stringy pulse or heavy.
2 Therapeutic Method
Treatment group: the granule that the oral embodiment of the present invention 3 is obtained, every day 2 times, each 1 bag.
Contrast one group: give Guishaotiaojing tablets treatment, medicine forms: Radix Bupleuri, Radix Angelicae Sinensis, Rhizoma Chuanxiong, the Radix Paeoniae Alba, Rhizoma Alismatis etc. (Hunan three nine-day periods after the winter solstice, pharmaceutical factory produced), oral, each 4, every day 3 times.
Contrast two groups: the granule that the oral embodiment of the present invention 6 is obtained, every day 2 times, each 1 bag.
Three groups are January is 1 course for the treatment of.Observe the curative effect after serveing on for 3 courses for the treatment of.
Treatments period is stopped using other drug, and wind sheltering is trembled with fear, and regulating spirit and emotion by oneself, avoid pungent food greasy product.
3. curative effect judging standard:
Criterion of therapeutical effect: formulate with reference to " Chinese medical disease Standardization of diagnosis and curative effect ".
Cure: the eumenorrhea rises, more than continuous 3 menstrual cycle and periods rules.
Take a turn for the better: menstruation recovery is risen, but the cycle is irregular or do not continue 3 menstrual cycle.
Invalid: menstruation is risen not yet.
4. therapeutic outcome:
In observation process, treatment group comes off 2 routine cases, contrasts one group of 3 routine case that come off, contrasts two groups of 2 routine cases that come off, and lost to follow-up after this 7 routine patient takes a turn for the better all to some extent, only effectively to add up, all the other all complete clinical observation.Treatment group efficacy result is as follows: clinical cure 42 example, and take a turn for the better 15 examples, invalid 3 examples, total effective rate 95%; Contrast one group of clinical cure 10 example, take a turn for the better 32 examples, invalid 18 examples, total effective rate 70%; Contrast two groups of clinical cure 11 examples, take a turn for the better 33 examples, invalid 16 examples, total effective rate 73.3%.Treatment group with contrast one group or contrast total effective rate between two groups and compare, difference has statistical significance (P < 0.05), contrast one group with contrast total effective rate between two groups and compare, no significant difference (P > 0.05).
In treatment group therapeutic process, vital sign is steadily and without serious adverse reactions such as allergy, treatment terminates the indexs such as the rear routine blood test to 58 routine patients, routine urinalysis, stool routine examination, excrement occult blood, Liver and kidney merit and carries out statistical procedures, show no obvious abnormalities, and arbitrarily change formula and proportioning, therapeutic effect of the present invention can not be reached completely.This clinical test results shows that the clinical application of we is safely and effectively, and relapse rate is low, is worth studying and applying further.
Experimental result shows: it is high that the pharmaceutical composition that the present invention treats blood stasis type menostasis has cure rate, dosage is few, short treating period, the advantage not easily recurred after healing, its determined curative effect, mild in medicine property and, there is not toxic and side effects and untoward reaction, safety coefficient is high, can be used as clinical active drug and applies.
Claims (7)
1. treat a pharmaceutical composition for blood stasis type menostasis, it is characterized in that, be prepared from by following Chinese crude drug: Radix Salviae Miltiorrhizae, Rhizoma Sparganii, Radix Rehmanniae Preparata, Radix Polygoni Multiflori Preparata, Fructus Schisandrae Chinensis, the Radix Astragali, Herba Leonuri, the Cortex Eucommiae, Radix Morindae Officinalis.
2. the pharmaceutical composition for the treatment of blood stasis type menostasis as claimed in claim 1, it is characterized in that, be prepared from by the Chinese crude drug of following weight portion: Radix Salviae Miltiorrhizae 12-16, Rhizoma Sparganii 8-12, Radix Rehmanniae Preparata 16-22, Radix Polygoni Multiflori Preparata 6-10, Fructus Schisandrae Chinensis 8-12, Radix Astragali 12-16, Herba Leonuri 8-12, Cortex Eucommiae 6-10, Radix Morindae Officinalis 10-14.
3. the pharmaceutical composition for the treatment of blood stasis type menostasis as claimed in claim 1, it is characterized in that, be prepared from by the Chinese crude drug of following weight portion: Radix Salviae Miltiorrhizae 14, Rhizoma Sparganii 10, Radix Rehmanniae Preparata 19, Radix Polygoni Multiflori Preparata 8, Fructus Schisandrae Chinensis 10, the Radix Astragali 14, Herba Leonuri 10, the Cortex Eucommiae 8, Radix Morindae Officinalis 12.
4. the pharmaceutical composition of the treatment blood stasis type menostasis as described in claim 1-3, is characterized in that, described pharmaceutical composition is prepared into oral formulations.
5. the pharmaceutical composition of the treatment blood stasis type menostasis as described in claim 1-3, is characterized in that, described oral formulations is tablet, capsule, granule or oral liquid.
6. the preparation method of the pharmaceutical composition of the treatment blood stasis type menostasis as described in as arbitrary in claim 1-3, it is characterized in that, comprise following steps: take the Radix Salviae Miltiorrhizae of recipe quantity, Rhizoma Sparganii, Radix Rehmanniae Preparata, Radix Polygoni Multiflori Preparata, Fructus Schisandrae Chinensis, the Radix Astragali, Herba Leonuri, the Cortex Eucommiae, Radix Morindae Officinalis, put into Chinese medicine grinder respectively to pulverize, 40 mesh sieves are crossed, mix homogeneously after pulverizing; Add decoction pot, decoct with water twice, add water 6-8 times amount for the first time, and warm macerating 4 hours decocts 3h, and second time amount of water is 4-6 times amount, and decocting time is 1.5h, merges decoction liquor, filters, obtains filtrate; Concentrating under reduced pressure filtrate, dry, put into Chinese medicine grinder and pulverize, after pulverizing, cross 80 mesh sieves; Add pharmaceutically acceptable carrier and be prepared into tablet, capsule, granule or oral liquid.
7. the purposes of the medicine as described in as arbitrary in claim 1-3 in the medicine of preparation treatment blood stasis type menostasis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610102495.8A CN105535719A (en) | 2016-02-24 | 2016-02-24 | Medicine composition for treating blood stasis type amenorrhoea |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610102495.8A CN105535719A (en) | 2016-02-24 | 2016-02-24 | Medicine composition for treating blood stasis type amenorrhoea |
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| CN105535719A true CN105535719A (en) | 2016-05-04 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106075078A (en) * | 2016-08-25 | 2016-11-09 | 王婷婷 | A kind of Chinese medicine composition treating amenorrhea caused by antipsychotic drug |
-
2016
- 2016-02-24 CN CN201610102495.8A patent/CN105535719A/en not_active Withdrawn
Non-Patent Citations (2)
| Title |
|---|
| 姜宁等: "《妇科金方》", 31 July 2001, 河北科学技术出版社 * |
| 康翠梅: "自拟补肾养血汤治疗虚证闭经52例", 《吉林中医药》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106075078A (en) * | 2016-08-25 | 2016-11-09 | 王婷婷 | A kind of Chinese medicine composition treating amenorrhea caused by antipsychotic drug |
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Application publication date: 20160504 |