CN1879838A - A Chinese medicine for treating threatened abortion - Google Patents
A Chinese medicine for treating threatened abortion Download PDFInfo
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- CN1879838A CN1879838A CN 200610079760 CN200610079760A CN1879838A CN 1879838 A CN1879838 A CN 1879838A CN 200610079760 CN200610079760 CN 200610079760 CN 200610079760 A CN200610079760 A CN 200610079760A CN 1879838 A CN1879838 A CN 1879838A
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Abstract
The invention relates to a Chinese medicament for treating threatened abortion, which comprises the following raw materials (by weight ratio): dipsacus root 9-12g, dodder seed 9-12g, Loranthus mulberry mistletoe 9-12g, perilla stem 9-12g, amomum fruit 9-12g, root of herbaceous peony 9-12g, white atractylodes rhizome 9-12g, cornus officinalis 9-12g, ichih fruit 9-12g, astragalus root 9-12g, pseudostellaria root 9-12g, arborvitae tops 9-12g, garden burnet root 9-12g, licorice root 9-12g, Chinese angelica root 3-6g, motherwort 3-6g, ophicalcite 2-3g, rhizoma Gastrodiae root 3-6g, gorgon euryale seed 3-6g and licorice root 3-6g.
Description
Technical field
The present invention relates to a kind of Chinese medicine compound, especially relate to a kind of Chinese medicine for the treatment of threatened abortion.
Background technology
Habitual abortion and threatened abortion are common clinically obstetrical and gynecological diseases, and the traditional Chinese medical science is called " habitual abortion, leakage tire, frequent fetal movement ".The incidence rate of the two accounts for 10% of spontaneous abortion.Clinical manifestation is to have soreness of waist stomachache or lower abdomen weigh down trimester of pregnancy with miscarriage to expand, or is cardinal symptom with a small amount of vaginal hemorrhage.Basic pathology habitual, threatened abortion is that embryo and fetus elder generation are dead, and decidua basalis is hemorrhage, or retroplacental haemorrhage, forms hematoma of posteroplacenta, stimulates the uterus, makes it to shrink discharge embryo and fetus.Modern medicine thinks, generation habitual, threatened abortion influences with inherited genetic factors, extraneous noxious substance, the disease of parent, repulsion that immune factor causes and maternal-fetal blood group incompatibility etc. are relevant.General downern, Hormone Replacement Therapy or the vitimin supplement etc. of using in the treatment.Chinese medical theory is thought, and basic pathogenesis habitual, threatened abortion is the spleen kidney deficiency, finally causes dashing appointing qi and blood disorder, and fetus is not solid so that frequent fetal movement takes place, and answers the spleen reinforcing kidney, replenishing QI and blood in treatment.
Common medicine has tranquilizer, hormones, vitamin at present.Wherein comparatively the common chemical medicine has hypnotic and sedative as stable, estrogen such as flavonoids, vitamin E, but prolonged application can produce very big untoward reaction.Continue during as early pregnancy to use tranquilizer, might cause the danger of children's's harelip, the anemia of pregnant woman takes heavy dose of tranquilizer for a long time, can influence the intelligence development of fetus.If using estrogen, preceding 3 months women of trimester of pregnancy might make the fetus opposite sexization; 3 months trimester of pregnancy were taken estrogen later on, can make the temporary increase of fetus genitals.A large amount of vitamin Es can make the hormone metabolism disorder.
Summary of the invention
The objective of the invention is to overcome the deficiencies in the prior art, provide that a kind of nourishing kidney is nourished blood, invigorating the spleen and benefiting QI, Gu Chong are appointed, antiabortive unit, regulating menstruation, hemostasis, raising endocrine hormone level, improve the pelvic cavity environment, promote the Chinese medicine of the treatment threatened abortion that palace body and embryo's blood supply oxygen supply, health invigorating, hemostasis are prevented miscarriage.
The present invention realizes in the following way:
A kind of Chinese medicine for the treatment of threatened abortion is characterized in that: it comprises the raw material of following parts by weight: Radix Dipsaci 9-12g, Semen Cuscutae 9-12g, Herba Taxilli 9-12g, Caulis Perillae 9-12g, Fructus Amomi 9-12g (back down), Radix Paeoniae Alba 9-12g, Rhizoma Atractylodis Macrocephalae (parched) 9-12g, Fructus Corni 9-12g, Fructus Alpiniae Oxyphyllae 9-12g, Radix Astragali Preparata 9-12g, Radix Pseudostellariae 9-12g, Cacumen Platycladi preparata 9-12g, charred Radix Sanguisorbae 9-12g, charred RADIX RUBIAE 9-12g, Radix Angelicae Sinensis 3-6g, Herba Leonuri 3-6g, Ophicalcitum 2-3g (taking after mixing it with water), Radix Boehmeriae 3-6g, Semen Euryales 3-6g, Radix Glycyrrhizae Preparata 3-6g;
It comprises the raw material of following parts by weight: Radix Dipsaci 10g, Semen Cuscutae 10g, Herba Taxilli 10g, Caulis Perillae 10g, Fructus Amomi 10g (back down), Radix Paeoniae Alba 10g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Fructus Corni 10g, Fructus Alpiniae Oxyphyllae 10g, Radix Astragali Preparata 10g, Radix Pseudostellariae 10g, Cacumen Platycladi preparata 10g, charred Radix Sanguisorbae 10g, charred RADIX RUBIAE 10g, Radix Angelicae Sinensis 5g, Herba Leonuri 5g, Ophicalcitum 2g (taking after mixing it with water), Radix Boehmeriae 5g, Semen Euryales 5g, Radix Glycyrrhizae Preparata 5.5g;
Described Chinese medicine can be made into decoction, pill, powder, unguentum, syrup, tablet, granule or powder preparation to be taken after being infused in boiling water or capsule;
Pill can be honeyed pill, the watered pill, paste pill or concentrated pill;
Described unguentum can be fluid extract, extractum or soft extract;
The decoction method of described decoction is: fry in shallow oil first with cold water, amount of water is 3 to 4 times of above-mentioned Chinese medicine total amount, soak half an hour after, add Fructus Amomi after 25 minutes at a simmer and fried in shallow oil again 5 minutes, leach medicine juice; Secondary is fried in shallow oil adding cold water, and amount of water is 2 to 3 times of above-mentioned Chinese medicine total amount, fries in shallow oil half an hour, leaches medicine juice for twice and mixes even the branch 2 times or 3-5 time, and potion on the one, warm and Ophicalcitum all part take orally simultaneously, avoid cold and uncooked food, and 3 days one courses of treatment, obey the 2-3 course of treatment altogether.
The present invention has following effect:
1) elder generation will be mended together the day after tomorrow, the QI and blood interpromoting relation in five elements, feotus vitality must be consolidated and blood ends tire peace: ancient Chinese medicine many according to clinical symptoms with threatened abortion called after " abdominal pain during pregnancy ", " vaginal bleeding during pregnancy ", " frequent fetal movement ", " habitual abortion ", " abdominal pain during pregnancy " etc., think that to be that the debility of CHONG and REN meridians, tire are become homeless foster; Deficiency of kidney-QI is due to insufficiency of the spleen anemia or vessels of the uterus retardance, insufficiency of blood and gas are not all right.Kidney is the congenital of woman, for Yuanyang this, main reproduction, if kidney qi loss, just can not the astringency inducing feotus vitality, and miscarry; The spleen being the foundation of acquired constitution, source of generating QI and blood, the taste vital essence is filled Sheng, and then chong channel is contained, and the sea of blood is full of, and tire is foster to some extent; CHONG meridian being the blood pool, REN meridian connecting with the uterus and pregnancy.Dash to appoint deficient, cloudy blood can not in rules metrostaxis, menorrhagia, puerperal or miscarriage hematochezia without cease; The deficient tire of conception vessel do not have lead then gestation hemorrhage (vaginal bleeding during pregnancy), frequent fetal movement, abdominal pain pain.So the present invention nourishes blood with nourishing kidney, invigorating the spleen and benefiting QI, Gu Chong appoints, and antiabortive unit, regulating menstruation, hemostasis are principle of treatment.Kidney qi is contained, and tire has direct bearing; The prosperous tire of gas has contained; Blood fills tire supports to some extent and reaches elder generation day after tomorrow with mending, the QI and blood interpromoting relation in five elements, and feotus vitality must be consolidated blood and ends the tire peace.
2) compatibility is rigorous, Wen Buhan not, and tonify without causing stagnation, to liability to abortion due to other factors and the miscarriage that takes place, good effect is also arranged: Radix Dipsaci, Semen Cuscutae, Herba Taxilli the kidney invigorating Gu Chong are monarch among the present invention, the prosperous self energy stoppage of growth of the fetus of kidney.This three medicine is the name side of preventing miscarriage " SHOUTAI WAN " of the well-known doctor Zhang Xichun of the Qing Dynasty, and checking has the curative effect of well preventing miscarriage through the centuries.Radix Pseudostellariae, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae QI invigorating warming YANG and strengthening the spleen also are monarch drug as a means of the source of vital function.Radix Astragali Radix Pseudostellariae warming YANG and strengthening the spleen wherein, Rhizoma Atractylodis Macrocephalae Radix Astragali QI invigorating stomach function regulating.Close the outstanding invigorating primordial QI deficiency of SHOUTAI WAN QI invigorating Gu Chong; Lid is aided with Chinese Angelica blood replonishing and blood because of deficiency and coldness of spleen-QI deficiency of YIN-blood then, promoting tissue regeneration by removing blood stasis, can draw again blood return through.Radix Angelicae Sinensis is joined Radix Astragali benefiting QI and nourishing blood, can make the QI and blood interpromoting relation in five elements, and negative and positive are received benefits, Yin grows while yang is generating, and the prosperous blood of gas is given birth to; Chong channel is solid, and is every and deficiency of the liver and kindey is in close relations, so again with Fructus Corni, Radix Paeoniae Alba liver and kidney tonifying, preserving YIN with astringents and nourishing blood is auxilliary.Radix Paeoniae Alba tonifying liver body and help liver usefulness, Radix Angelicae Sinensis are aided with the Radix Paeoniae Alba tonifying liver that can nourish blood; For preventing to grow greasy slow-witted the benefit, assistant Fructus Amomi stomach function regulating is amusing, the chest stuffiness relieving of regulating the flow of vital energy, and it is thin that invigorating middle warmer is had, and be equipped with Caulis Perillae again and dredge the gas that stagnates, and antiabortive unit, help we's the bar of evacuating to reach, mechanism of qi must be relaxed, blood deficiency must be supported; Fructus Corni nourishing the liver and kidney benefit vital essence; Fructus Alpiniae Oxyphyllae strengthening the spleen stomach, reason vigour; Semen Euryales spleen reinforcing kidney, beneficial vital essence are longer than the solid warp of spleen reinforcing especially.The flat tonifying liver spleen of three medicines kidney essense can containing vital essence, training unit reinforces the kidney, so that positive cloudy helping, interdependence between yin and yang; Assistant blood-cooling hemostatic Cacumen Platycladi preparata, charred Radix Sanguisorbae can stop blooding, and receive the property of the warm-dryness syndrome of joining medicines such as stilbene again, and Radix Boehmeriae arresting bleeding and miscarriage prevention, Ophicalcitum can stop blooding, but blood stasis dispelling also can replenish mineral again.Radix Rubiae is stopped blooding and is not stayed the stasis of blood.Add a small amount of Herba Leonuri promoting tissue regeneration by removing blood stasis, can stop blooding, can inspire blood vessels antiabortive again; Radix Glycyrrhizae is for making sweet temperature QI invigorating, coordinating the actions of various ingredients in a prescription.The Radix Paeoniae Radix Glycyrrhizae is the energy relieving spasm to stop pain especially; Warming YANG and strengthening the spleen of the present invention, harmonizing the functional activities of vital QI, hemostasis by invigorating QI, the property of medicine is gentle, has not both had the fraud of warm-dryness syndrome hematozemia impairment of YIN, does not have cold and cool stagnating again, and the suspicion of the stasis of blood is stayed in hemostasis.It is current stagnant to play temperature altogether, nourishing kidney spleen invigorating, the effect of nourishing blood and hemoslasis.All medicines share, coordination of potent and mild therapies, warming YANG hemostasis and impairment of YIN not, nourishing YIN and benefiting blood and do not hinder spleen.
3) improve the pregnancy period hormone serum level: Semen Cuscutae, Radix Dipsaci, Herba Taxilli, Radix Dipsaci, the Radix Paeoniae Alba etc. all have the uterine smooth muscle of inhibition to shrink among the present invention, the effect of short corpus luteum, short developing womb.Wherein SHOUTAI WAN contains various trace elements according to modern pharmacological research, the damage of energy free radical resisting and minimizing monster take place, short corpus luteum, promotion uterus and the development of ovary, suppress the tetanic property contraction of uterine smooth muscle, the modulability hormonal balance, make LH (luteotropic hormone), raise with the level of P (progesterone), Semen Cuscutae also has estrogenic activity, also can promote uterine growth to grow.The excited reticuloendothelial system of Radix Angelicae Sinensis energy has the absorption of promotion and elimination effect to sedimentary antigen antibody complex.The Rhizoma Atractylodis Macrocephalae can improve body cell and humoral immune function.Fructus Amomi, Radix Angelicae Sinensis all can play antiplatelet aggregation and anticoagulation by different links, and miscarriage has good result to autoimmunity.Modern pharmacology research finds that also many Chinese medicines of preventing miscarriage have dual regulation, can act on maincenter and ovary as peony and licorice decoction, contraction movement to tissues such as fallopian tube, uterus, vascular smooth muscles has dual regulation, the smooth muscle spasm of alleviation, analgesic effect are arranged, can also directly act on ovary, the effect of endocrine regulation hormonal readiness is arranged.The pharmacological basis of Radix Angelicae Sinensis effect not only has its excited to uterus smooth muscle contraction function and suppress regulating action, also relates to anti-inflammatory and analgesic effect, improves the hemorheology feature, increases many-sided effect such as organic blood flow volume.Radix Astragali QI invigorating and blood producing has protective effect to hemopoietic and immune system, improves or recovers erythrocytic function.
4) improve environment in the pelvic cavity: find that according to modern pharmacological research blood rearing interpolating kidney Chinese medicine can improve the blood circulation of pelvic cavity, uterus and Placenta Hominis; Improve and impel the growth of placental villi; Maintain and the getting in touch of fine hair and fundus of uterus decidua when strengthening early pregnancy; Suppress uterine contraction, prevent fine hair and decidua blood supply oxygen supply for want of and peel off from Uterus wall and to miscarry.Many Chinese medicines of preventing miscarriage not only can improve hemorheology and blood viscosity is unusual, the mediation microcirculation, and therapeutical effect can also play by immunologic function in the adjustment body in conditioning tissue metabolism, and is particularly remarkable to the endocrine hormone regulating action.Hemorrhage can suppress the colporrhagia that causes because of the blood sinus opening; The Radix Angelicae Sinensis Radix Paeoniae Alba can be alleviated smooth muscle spasm, alleviates because the paroxysmal hypogastralgia that hematocele in uterine cavity stimulates uterine contraction to occur; The Rhizoma Atractylodis Macrocephalae has direct effect to uterine smooth muscle, and the contraction of uterus irritability, tonic contraction are all had remarkable inhibition or antagonism.And to dead embryo, the dual regulation of benefiting QI and nourishing blood, the antiabortive Chinese medicine that reinforces the kidney can also impel pregnant capsule to peel off to make it to discharge fully and can prevent massive hemorrhage by strengthening uterine contraction.
5) to the adjusting of neuro humor endocrine function: the body and mind wound that causes such as fatigue, emotion acute variation, living environment change, body illness, malnutrition and habitual abortion and hormonal readiness is changed and have influence on cerebral cortex to the cause economic loss and to the multiple factors such as fear of infertility, the contraction that causes the uterus make the embryo dead in uterus or disturb gonad axis adjusting, influence ovarian function, cause luteal insufficiency, the secretion progestogen are not enough and miscarry.The integral body of Chinese medicine sees and three categories of etiologic factors system benefit, determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs adjust and the treatment disease aspect the scientific methods opinion is provided for preventing miscarriage, match with the etiology and pathology of the multiple factor of miscarrying, meet the characteristics of modern biology-psychology-social medicine pattern.Change by measuring serum hormone, monitor the fetal development situation, the advantage of preventing miscarriage of Chinese medicine can be expressed by the index of scientific quantification, thereby obtain satisfied hormone environment to be fit to embryo's growth in conjunction with B ultrasonic.Many discovering, the Chinese medicine that nourishes blood of tonifying Qi of the kidney has the effect of similar vitamin and parahormone sample, not only can strengthen the effect of progesterone, also can act on the different links of hypothalamic-pituitary-ovarian axis, thereby adjusting neuro humor hormonal system and immune system are harmonious.
6) the rate height of preventing miscarriage: be devoted to the Chinese traditional treatment research of threatened abortion for many years in person, accumulated a large amount of cases, begin modern scientific research methods for designing such as applying clinical statistics, epidemiology and evidence-based medicine EBM from calendar year 2001, test rating by objective quantification, Chinese medicine provided by the invention is carried out clinical and experimental study, obtain good curative effect, the rate of preventing miscarriage is 76.98% (greater than Progesterone 43.59%).
The medicine effect of respectively distinguishing the flavor of among the present invention and pharmacological action are as follows:
1) Radix Dipsaci: the bitter temperature of nature and flavor, return the Liver and kidney warp.Effect: invigorating the liver and kidney, bone and muscle strengthening, arresting bleeding and miscarriage prevention, promoting blood circulation.Can invigorating the liver and kidney can appoint by Gu Chong again, be applicable to cards such as the metrorrhagia of the debility of CHONG and REN meridians and gestation hemorrhage, frequent fetal movement.This is built up one's health by taking tonic and can declare, and row and not letting out has tonify without causing stagnation to the metrorrhagia fetal movement, and the effect of ending is arranged in the row." herbal classic " " obeys physical strength profiting " for a long time; " big bright book on Chinese herbal medicine " " help gas, blood circulation regulating is mended five kinds of strain and seven kinds of impairment.All diseases of the antenatal back of married woman, yellowish complexion edema due to deficiency, vaginal bleeding during pregnancy uterus are cold ".Pharmacological research: contain Radix Dipsaci alkali, volatile oil, vitamin E and some trace element.The effect of excited uterus is arranged.
2) Semen Cuscutae: the property acrid-sweet flavor is flat, returns lung kidney large intestine channel.Effect: the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity, antiabortive antidiarrheal.This medicine is reported gas neutralization, temperature and not dry, tonify without causing stagnation, but can kidney-replenishing tonifying YIN essence again, also have the strengthening the spleen anti-diarrhea effect.Be the flat good medicine of mending liver,spleen,kidney.Be used for vaginal bleeding due to deficiency of the kidney during pregnancy, frequent fetal movement." property of medicine opinion ": " control man woman cold caused by deficiency, sperm adding and marrow healthing goes the pain in the lumbar region knee joint cold." chemical constituent: glucoside-containing, sterol, flavonoid and several amino acids and trace element.Pharmacological research has estrogen-like effects, and uterus weight is increased; Can also the endocrine regulation hormonal readiness, improve hypophysis to LRH (luteinizing hormone releasing hormone) and ovary reactivity to LH (lutropin).Semen Cuscutae tincture, preserved material can strengthen the contractility of the Bufo siccus heart that exsomatizes, and can make its blood pressure drops to anesthetized dog, and isolated uterine is had excitation.
3) Herba Taxilli: nature and flavor are bitter flat, return the Liver and kidney warp.Effect: wind-damp dispelling, invigorating the liver and kidney, nourishing blood and preventing abortion." herbal classic " " antiabortive, fill skin, the hard tooth of sending out, long man.”。" big bright book on Chinese herbal medicine " " helps muscles and bones, beneficial blood vessels ".Pharmacological research: contain flavonoids such as avicularin.Calm diuresis is arranged, can increase the heart coronary flow.
4) Caulis Perillae: property and flavor of peppery and warm, return the lung spleen channel, effect: deliver cold expelling, promoting the circulation of QI to alleviate the stagnation in middle-JIAO, solving toxin of fish and crab.Compendium of Material Medica record " antiabortive with the blood warming middle-JIAO to relieve pain " we get its antiabortive length of regulating the flow of vital energy, and dredge the gas that stagnates, antiabortive unit.The modern pharmacological research main component is volatile oil (perillaldehyde), flavone compound and saccharide, tannin class etc.Can secrete by facilitating digestion liquid, increase gastrointestinal peristalsis, preventing or arresting vomiting.
5) Fructus Amomi: property and flavor of peppery and warm, return the taste kidney channel, effect: removing dampness circulation of qi promoting, warming spleen and stopping diarrha, antiabortive.Compendium of Material Medica record " reason vigour dispelling stagnant Qi ".It is warm in nature and not dry, circulation of qi promoting and dispelling the stagnated QI not, in the accent and not damaging the spleen and stomach.Can the antiabortive preventing or arresting vomiting of harmonizing the functional activities of vital QI.The modern pharmacological research main component is a volatile oil, and fragrant digestion promoting function is arranged, and can inspire function, the secretion of facilitating digestion liquid of stomach, and can get rid of gastral pneumatosis.
6) Radix Paeoniae Alba: the nature and flavor picric acid is slightly cold.Return Liver Channel.Effect: suppressing liver-YANG, the yin fluid astringing that nourishes blood, easing the affected liver to relieve pain." herbal classic " " main pathogen stomachache, pain relieving, diuresis, QI invigorating." for treating the good medicine of all pains.Contain paeoniflorin, benzoic acid, tannin, volatile oil, cupreol etc.Pharmacological research finds that analgesia is arranged, calmness, antiinflammatory, spasmolytic, anoxia enduring and the endocrine-immune system function had dual regulation.To the animal intestine in vitro with at body stomach, uterine smooth muscle inhibitory action is arranged.Paeoniflorin has inhibitory action to the central nervous system.
7) Rhizoma Atractylodis Macrocephalae (parched): property bitter but sweet flavor temperature, return the taste warp.Effect: invigorating the spleen and replenishing QI, dampness diuretic, strengthening superficial resistance to stop perspiration.Be the invigorating the spleen and replenishing QI key medicine.Again can be antiabortive." pearl sac ": " dehumidifying QI invigorating and middle YANG invigorating, the antiabortive heat clearing away of assistant Radix Scutellariae ".Pharmacological research contains volatile oil, atractylol, Rhizoma Atractylodis ketone and several amino acids, retinoid material.Gastrointestinal function there is dual regulation, can promotes the intestines and stomach secretion, obvious and persistent diuresis is arranged, can promote the particularly discharge of sodium of electrolyte.But also blood sugar lowering, the liver protecting, prevent that liver glycogen from reducing.Can improve the cell and the humoral immune function of body, blood circulation promoting, weight increase, muscular strength strengthens, and has strong and immanoprotection action.Uterine smooth muscle is had direct effect, can suppress uterine contraction.
8) Fructus Corni: the sweet acid temperature of nature and flavor, return the Liver and kidney warp.Effect: liver and kidney tonifying, restrain astringent or styptic treatment for spontaneous sweating.The moon that can invigorating the liver and kidney again can warming and recuperating the kidney-YANG, is the key medicine of flat simply nourishing YIN sun." not Lu ": " reinforcing YIN-essence, benefit is smart, settling five organs, logical nine orifices, brute force makes eye bright ".Pharmacological research contains vitamin A, cornin, Saponin, tannin, ursolic acid, gallic acid, malic acid, tartaric acid etc.Diuresis and blood pressure lowering, bacteriostasis are arranged.In vitro tests can be killed the white mice ascites cells.The leukocyte that causes because of chemotherapy and radiotherapy descended the effect of rising.Cornin toxicity is very low, and more weak parasympathomimetic effect is arranged.
9) Fructus Alpiniae Oxyphyllae: property and flavor of peppery and warm, return the spleen kidney channel.Effect: the solid warp of the kidney invigorating, urine reducing, warming spleen and stopping diarrha, take the photograph saliva and spittle.The hot wet perfume (or spice) of this medicine, energy warming the spleen warming the stomach, the kidney tonifying fire of holding concurrently.Materia Medica of Decoction " strengthening the spleen stomach, reason vigour, the empty sliding drop of the kidney invigorating ".Pharmacological research contains volatile oil, various trace elements and abundant B group vitamin, and 17 seed amino acids, wherein zinc, manganese VB1VB2 and glutamic acid and Radix Asparagi content are the highest, are higher than general yang-tonifying drug.It is synthetic to suppress prostaglandin, and heart tonifying, calcium antagonism are arranged.The large artery trunks that suppresses significantly to be caused by potassium chloride shrinks.
10) Radix Astragali Preparata: the sweet tepor of nature and flavor, return the spleen lung meridian.Effect: tonifying Qi and lifting yang, benefit is defended consolidating superficial resistance, promoting pus discharge and tissue regeneration strengthening, diuretic detumescent." not Lu ": " it be deficient to mend the husband, the five kinds of over strain weakness and emaciation.QI invigorating, Li Yin gas ".Pharmacological research contains polysaccharide, flavone compound, choline, folic acid, aminoacid, cupreol and various trace elements etc.Class sex hormone function and stimulating central nervous system systemic effect are arranged.Can prevent that liver glycogen from reducing, protect the liver, diuresis, blood pressure lowering, defying age and anti-stress, Detoxication.Strengthen the phagocytic function of reticuloendothelial system, regulate immunity, promote cell growth and regeneration, anti-hypoxia lacks sugar, disease resistance enhancemen.Hemopoietic and immune system there is protective effect, heart tonifying, blood vessel dilating, improvement circulation, the ability of raising leukocyte inducement interferon, enhance immunity, antiviral.The effect that stagnates of its qi-supplementing, blood-engendering, QI invigorating row mainly shows blood system and hemorheological influence.
11) Radix Pseudostellariae: the property sweet and slightly bitter taste is flat, effect: tonifying QI to produce body fluid.Power is thin with Radix Ginseng for its merit, relatively the cloudy gas of tonification.Be the product of clear benefit simply.Chemical constituent: contain Saponin, fructose, starch.Can treat the neurasthenia, children's's sweating due to debility.
12) Cacumen Platycladi preparata: bitterness is slightly cold, and returns lung liver large intestine channel.Effect: cooling blood for hemostasis, cough-relieving, hair growth promoting." not Lu ": " main haematemesis, epistaxis, dysentery blood, metrorrhagia are red white ".Pharmacological research contains volatile oil, pinane is rare, Oleum Caryophylli is rare, pine and cypress bitter principle, absinthol, vitamin C, alkaloid etc.The effect of shortening bleeding time and clotting time is arranged.
13) charred Radix Sanguisorbae: the nature and flavor picric acid is slightly cold, and returns liver stomach large intestine channel.Effect: cooling blood for hemostasis, convergence detoxifcation." big bright book on Chinese herbal medicine ": " menstruation is more than, metrorrhagia, all blood disorders in antenatal back ".Pharmacological research contains tannin, sanguisorbin, phenolic acids, retinoid material and various trace elements.Can shorten hemorrhage and clotting time, the activity of platelet increasing, raising is the anoxia ability.
14) charred RADIX RUBIAE: the nature and flavor bitter cold, return Liver Channel.Effect: cooling blood for hemostasis, activating blood and removing stasis.Be gynecological's key medicine." not Lu ": " control blood, in collapse hematochezia ".Pharmacological research contains purple alizarin, psedopurpurin, madder color.Antibacterial, leukocyte increasing, hemorrhage, the clotting time effect of shortening are arranged.Heart blood supply be can also strengthen, energy metabolism of myocardial and oxygen supply, anoxia enduring improved.
15) Radix Angelicae Sinensis: nature and flavor Gan Xinwen, return liver heart spleen channel.Effect: tonifying blood and regulating menstruation, promoting blood circulation and stopping pain, loosening bowel to relieve constipation.Can enrich blood, can invigorate blood circulation again, the promoting the circulation of QI to relieve pain of holding concurrently for mending the product of profit, have the merit of invigorating blood circulation again.Cure mainly all blood disorders, will product for what control disorders of blood, be called as gas medicine in the blood, gynecological's good medicine particularly, all menoxenias, tire produce all diseases, and no matter blood deficiency stasis all commonly usedly is principal agent.Compendium of Material Medica " is controlled headache, all pains of trusted subordinate, intestine moistening stomach, muscles and bones, skin.Enrich blood with blood ".Pharmacological research contains volatile oil, folinic acid, nicotinic acid, B-sitosterol, VB12 etc.Wherein contained B12 and folic acid class material have anti-pernicious anemia effect.The uterus there is " two phasic properties " effect excited and inhibition, both can have suppressed hysterospasm, can make blood capable vigorous again, promote developing womb, and can reduce pelvic congestion by loosening bowel to relieve constipation, to reach indirect therapeutic purposes with pain relieving.
16) Herba Leonuri: the property hardship is slightly cold, and returns liver heart urinary bladder channel.Effect: blood circulation promoting competent silt, diuresis detoxifcation.Be gynecological's multiparity key medicine.The Compendium of Material Medica record is controlled " metrorrhagia and metrostaxis married woman tire produces all diseases " and is had the effect of promoting tissue regeneration by removing blood stasis.Its main component of modern pharmacological research contains the multiple alkaloid of leonurine first, leonurine the second grade and vitamin, potassium chloride and Flavonoid substances etc.Its activating blood and removing stasis effect mainly with improve hematodinamics, improve hemorheology and microcirculation improvement is relevant.
17) Ophicalcitum: Ore class medicine, it is flat that nature and flavor are sour and astringent, returns Liver Channel.Effect: hemostasia and dissipation blood stasis.Can stop blooding, can change silt again.Compendium of Material Medica " is controlled all traumas of losing blood, internal hemorrhage due to trauma, corneal nebula."; " good help book on Chinese herbal medicine " " main incised wound hemostasis, treat puerpera's bruise again, stagnant blood goes out ".Pharmacological research: contain a large amount of calcium and magnesium carbonate minute quantity ferrum, aluminum etc., can increase calcium ion concentration in the blood, make the blood vessel densification, prevent that again blood plasma from oozing out and promoting the effect of blood coagulation, replenish body trace element.Usage: take after mixing it with water.
18) Radix Boehmeriae: the sweet cold of nature and flavor, GUIXIN Liver and kidney urinary bladder channel.Effect: arresting bleeding and miscarriage prevention, clearing away heat and promoting diuresis.Be antiabortive special medicine." big bright book on Chinese herbal medicine " " controlled septum cordis heat, leaked the tire hematochezia ".Contain phenols, triterpenes, chlorogenic acid, flavonoid and organic acid, alkaloid, aminoacid and polysaccharide etc.The effect that promotes blood clotting, shortens the blood clotting time is arranged.
19) Semen Euryales: the plant kernel, the property sweet-puckery flavor is flat, returns the spleen kidney channel.Effect: invigorating the spleen to arrest diarrhea, the puckery scape that reinforces the kidney, leukorrhagia stopping.Merit is similar to Rhizoma Dioscoreae, is longer than the spleen reinforcing kidney." herbal classic " includes, " main arthralgia chiefly caused by damp pathogen waist and knee, invigorating middle warmer remove sudden and violent disease, beneficial vital essence, strong will is made us normal hearing and eyesight ".Chemical constituent: contain protein, fat, carbohydrate, calcium, phosphorus, ferrum, riboflavin, ascorbic acid.Consumption: 3-6g.
20) Radix Glycyrrhizae Preparata: nature and flavor are sweet flat, GUIXIN lung taste warp.Effect: the QI invigorating invigorating middle warmer, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain relaxes the property of medicine.The merit that coordinating the actions of various ingredients in a prescription is arranged." not Lu ": " sharp vim and vigour are separated hundred poison of drug for warming the middle warmer and descending qi, qualcomm meridian ".Pharmacological research contains glycyrrhizin, mainly is potassium, the calcium salt of glycyrrhizic acid, flavone compound etc.Heart tonifying, detoxifcation, antiinflammatory antiallergic, spasmolytic and the effect of class adrenal cortex are arranged.
Following table is for to have the anemia of pregnant woman of threatened abortion to use the case of medicine provided by the invention to 126 conceived different times:
| 25 | 5 weeks | 40 | 3000 | 11 | 8900 | 100 | 25 | 5 weeks | 41 | 2100 | 35 | 800 | 21 | Miscarriage | |
| 26 | 5 weeks | 40 | 2600 | 23 | 7600 | 135 | 26 | 5 weeks | 41 | 2000 | 22 | 500 | 2 | Miscarriage | |
| 27 | 5 weeks | 41 | 850 | 12.5 | 800 | 15 | Miscarriage | 27 | 5 weeks | 41 | 5000 | 120 | 160000 | 200 | |
| 28 | 5 weeks | 41 | 3550 | 31.5 | 33000 | ＞200 | 28 | 5 weeks | 41 | 8900 | 100 | 10340 | 178 | ||
| 29 | 5 weeks | 41 | 175 | 20 | 17600 | ＞200 | 29 | 6 weeks | 42 | 8000 | 120 | 12000 | 150 | Miscarriage | |
| 30 | 6 weeks | 42 | 4000 | 52 | 9860 | 155 | 30 | 6 weeks | 42 | 6700 | 100 | 12300 | 200 | ||
| 31 | 6 weeks | 42 | 67500 | 177.5 | 104000 | 117 | 31 | 6 weeks | 42 | 1600 | 60 | 780 | 45 | Miscarriage | |
| 32 | 6 weeks | 42 | 8000 | 174.5 | 5000 | 134 | Miscarriage | 32 | 6 weeks | 43 | 2500 | 78 | 800 | 29 | Miscarriage |
| 33 | 6 weeks | 42 | 6500 | 100 | 12000 | 200 | 33 | 6 weeks | 43 | 12000 | 156 | 130800 | 200 | ||
| 34 | 6 weeks | 42 | 5000 | 45 | 10500 | 176 | 34 | 6 weeks | 43 | 1760 | 21 | 453 | 12 | Miscarriage | |
| 35 | 6 weeks | 42 | 2000 | 14 | 3600 | 175 | 35 | 6 weeks | 43 | 1600 | 12 | 550 | 2.1 | Miscarriage | |
| 36 | 6 weeks | 43 | 10200 | ＞200 | 20600 | ＞200 | 36 | 6 weeks | 43 | 800 | 23 | 5900 | 198 | ||
| 37 | 6 weeks | 43 | 6000 | 120 | 5000 | 75 | Miscarriage | 37 | 6 weeks | 44 | 23000 | 154 | 78900 | 198 | |
| 38 | 6 weeks | 43 | 4000 | 200 | 7900 | 189 | 38 | 6 weeks | 44 | 10200 | 76 | 76840 | 200 | ||
| 39 | 6 weeks | 43 | 2300 | 126 | 6000 | 200 | 39 | 6 weeks | 44 | 27000 | 120 | 142000 | 187 | Miscarriage | |
| 40 | 6 weeks | 43 | 2500 | 65 | 100 | 23 | Miscarriage | 40 | 6 weeks | 44 | 10000 | 56 | 23000 | 134 | |
| 41 | 6 weeks | 44 | 16400 | 168 | 32000 | 200 | 41 | 6 weeks | 44 | 1150 | 2.3 | 120 | 1 | Miscarriage | |
| 42 | 6 weeks | 44 | 25000 | 173 | 54000 | ＞200 | 42 | 6 weeks | 45 | 12000 | 27 | 23800 | 174 | ||
| 43 | 6 weeks | 44 | 37600 | ＞200 | 38960 | ＞200 | 43 | 6 weeks | 45 | 10600 | 98 | 32100 | 156 | ||
| 44 | 6 weeks | 44 | 1800 | 50 | 260 | 2 | Miscarriage | 44 | 6 weeks | 45 | 1987 | 55 | 890 | 10 | Miscarriage |
| 45 | 6 weeks | 44 | 2000 | 146 | 4500 | 186 | 45 | 6 weeks | 46 | 12100 | 43 | 320000 | ＞200 | ||
| 46 | 6 weeks | 45 | 7600 | 67 | 20000 | 115 | 46 | 6 weeks | 46 | 2800 | 59 | 1200 | 43 | Miscarriage | |
| 47 | 6 weeks | 45 | 21000 | 183.5 | 51400 | 161.5 | 47 | 6 weeks | 46 | 3450 | 110 | 2100 | 55 | Miscarriage | |
| 48 | 6 weeks | 45 | 16000 | ＞200 | 36000 | ＞200 | 48 | 6 weeks | 47 | 43100 | 98 | 231000 | 200 | ||
| 49 | 6 weeks | 45 | 10060 | 44 | 460 | 3.2 | Miscarriage | 49 | 6 weeks | 47 | 32000 | 56 | 102000 | 120 | Miscarriage |
| 50 | 6 weeks | 45 | 3500 | 154 | 8600 | 200 | 50 | 6 weeks | 47 | 4000 | 150 | 2600 | 100 | Miscarriage | |
| 51 | 6 weeks | 46 | 6800 | 154 | 18000 | 200 | 51 | 6 weeks | 47 | 4500 | 120 | 4500 | 110 | Miscarriage | |
| 52 | 6 weeks | 46 | 4460 | 69 | 9800 | 148 | 52 | 6 weeks | 47 | 5000 | 100 | 2700 | 12 | Miscarriage | |
| 53 | 6 weeks | 47 | 3500 | 1 | 37050 | ＞200 | 53 | 6 weeks | 47 | 342000 | ＞200 | 440000 | ＞200 | ||
| 54 | 6 weeks | 47 | 800 | 14 | 800 | 14 | Miscarriage | 54 | 6 weeks | 47 | 128000 | 198 | 230000 | 200 | |
| 55 | 6 weeks | 47 | 1200 | 55 | 7666 | 200 | 55 | 6 weeks | 48 | 1000 | 58 | 89000 | 200 | ||
| 56 | 6 weeks | 47 | 800 | 22 | 1200 | 200 | Miscarriage | 56 | 6 weeks | 48 | 10222 | 23 | 23800 | 120 | Miscarriage |
| 57 | 6 weeks | 47 | 2460 | 76 | 5600 | 168 | 57 | 6 weeks | 48 | 110000 | 123 | 213000 | 200 | ||
| 58 | 6 weeks | 47 | 6700 | 12 | 34500 | 167 | 58 | 6 weeks | 48 | 20000 | 200 | 43000 | 180 | Miscarriage | |
| 59 | 6 weeks | 47 | 45600 | 169 | 36270 | 200 | 59 | 6 weeks | 48 | 20000 | 128 | 48000 | 200 | ||
| 60 | 6 weeks | 47 | 5540 | 34 | 12300 | 200 | 60 | 6 weeks | 48 | 44 | 2 | 18 | 0.7 | Miscarriage | |
| 61 | 6 weeks | 48 | 26700 | ＞200 | 45000 | ＞200 | 61 | 7 weeks | 49 | 8000 | 67 | 6700 | 32 | Miscarriage | |
| 62 | 6 weeks | 48 | 870 | 12 | 180 | 10 | Miscarriage | 62 | 7 weeks | 50 | 68900 | 123 | 120000 | 200 | |
| 63 | 6 weeks | 48 | 6000 | 54 | 28900 | 200 | 63 | 7 weeks | 50 | 2378 | 65 | 2000 | 44 | Miscarriage | |
| 64 | 6 weeks | 48 | 23000 | 128 | 45000 | ＞200 | 64 | 7 weeks | 50 | 4500 | 78 | 3090 | 32 | Miscarriage | |
| 65 | 6 weeks | 48 | 1240 | 55 | 2800 | 169 | 65 | 7 weeks | 50 | 7800 | 23 | 10200 | 123 | ||
| 66 | 6 weeks | 48 | 3600 | 45 | 7600 | 89 | 66 | 7 weeks | 50 | 9800 | 120 | 210000 | 200 | ||
| 67 | 6 weeks | 48 | 2470 | 12 | 7800 | 123 | 67 | 7 weeks | 50 | 3200 | 26 | 8700 | 120 | ||
| 68 | 7 weeks | 50 | 40500 | 200 | 40500 | ＞200 | Miscarriage | 68 | 7 weeks | 50 | 4320 | 55 | 12800 | ＞200 | |
| 69 | 7 weeks | 50 | 2450 | 30.5 | 1000 | 20 | Miscarriage | 69 | 7 weeks | 50 | 5400 | 79 | 23800 | 200 |
| 70 | 7 weeks | 50 | 1000 | 19 | 1050 | 19 | Miscarriage | 70 | 7 weeks | 50 | 6520 | 45 | 12000 | 200 | Miscarriage |
| 71 | 7 weeks | 50 | 28000 | 200 | 32600 | ＞200 | 71 | 7 weeks | 50 | 590 | 23 | 12800 | 176 | ||
| 72 | 7 weeks | 50 | 27000 | 200 | 29000 | 198 | 72 | 7 weeks | 50 | 4300 | 12 | 8900 | 120 | ||
| 73 | 7 weeks | 50 | 295 | 2.4 | 600 | 45 | 73 | 7 weeks | 51 | 6700 | 89 | 6900 | 120 | Miscarriage | |
| 74 | 7 weeks | 50 | 1600 | 50 | 8400 | 200 | Miscarriage | 74 | 7 weeks | 53 | 102700 | 156 | 7860 | 78 | Miscarriage |
| 75 | 7 weeks | 50 | 6300 | 100 | 8600 | 178 | 75 | 7 weeks | 53 | 9000 | 48 | 12000 | 200 | ||
| 76 | 7 weeks | 50 | 300 | 2.6 | 60 | 1 | Miscarriage | 76 | 7 weeks | 53 | 9800 | 110 | 4800 | 34 | Miscarriage |
| 77 | 7 weeks | 50 | 2356 | 56 | 5500 | 123 | 77 | 7 weeks | 53 | 10000 | 100 | 23900 | 167 | Miscarriage | |
| 78 | 7 weeks | 50 | 1650 | 36 | 8900 | 178 | 78 | 7 weeks | 53 | 12000 | 87 | 287000 | ＞200 | ||
| 79 | 7 weeks | 51 | 6580 | 54 | 9900 | 155 | 79 | 7 weeks | 54 | 9800 | 56 | 12000 | 132 | Miscarriage | |
| 80 | 7 weeks | 51 | 170 | 4.5 | 19500 | ＞200 | 80 | 7 weeks | 54 | 8900 | 37 | 142000 | 200 | ||
| 81 | 7 weeks | 53 | 39300 | 174.5 | 3960 | 186 | 81 | 8 weeks | 56 | 2350 | 12 | 2300 | 2.5 | Miscarriage | |
| 82 | 7 weeks | 53 | 19200 | 200 | 49250 | ＞200 | 82 | 8 weeks | 57 | 34700 | 200 | 34800 | 200 | ||
| 83 | 7 weeks | 53 | 18300 | 200 | 24500 | 200 | 83 | 8 weeks | 60 | 123000 | ＞200 | 230000 | ＞200 | ||
| 84 | 7 weeks | 53 | 7680 | 200 | 1500 | 50 | Miscarriage | 84 | 8 weeks | 60 | 800 | 3 | 230 | 1 | Miscarriage |
| 85 | 7 weeks | 53 | 2400 | 50 | 21780 | 200 | 85 | 8 weeks | 60 | 84300 | 200 | 98000 | 200 | ||
| 86 | 7 weeks | 53 | 22500 | 144 | 30000 | 182 | 86 | 8 weeks | 60 | 78000 | 120 | 102000 | 189 | Miscarriage | |
| 87 | 7 weeks | 54 | 3000 | 55 | 860 | 34 | Miscarriage | 87 | 8 weeks | 60 | 23500 | 53 | 85000 | 178 | |
| 88 | 7 weeks | 55 | 50400 | 171.5 | 86630 | ＞200 | 88 | 8 weeks | 60 | 24800 | 156 | 12370 | 100 | Miscarriage | |
| 89 | 8 weeks | 56 | 2360 | 43 | 15600 | 189 | 89 | 8 weeks | 61 | 2340 | 11 | 560 | 0.9 | Miscarriage | |
| 90 | 8 weeks | 57 | 11650 | ＞200 | 16400 | 175.5 | 90 | 8 weeks | 62 | 48900 | 120 | 150000 | 200 | ||
| 91 | 8 weeks | 58 | 2700 | 53 | 6800 | 176 | 91 | 9 weeks | 63 | 548000 | 200 | 843700 | 200 | ||
| 92 | 8 weeks | 59 | 6700 | 69 | 8690 | 200 | 92 | 9 weeks | 63 | 23500 | 178 | 45000 | 200 | Miscarriage | |
| 93 | 8 weeks | 60 | 5830 | 67 | 10800 | 134 | 93 | 9 weeks | 64 | 94800 | ＞200 | 96000 | ＞200 | ||
| 94 | 8 weeks | 60 | 880 | 65 | 220 | 15 | Miscarriage | 94 | 9 weeks | 64 | 10570 | 12 | 8900 | 11 | Miscarriage |
| 95 | 8 weeks | 61 | 5100 | 65 | 10230 | 198 | 95 | 9 weeks | 65 | 34780 | 137 | 56000 | 156 | Miscarriage | |
| 96 | 8 weeks | 61 | 12000 | 124 | 14000 | 169 | 96 | 9 weeks | 65 | 54800 | 120 | 80000 | 200 | ||
| 97 | 8 weeks | 61 | 10000 | 154 | 68000 | 200 | 97 | 9 weeks | 65 | 65000 | 155 | 3785 | 45 | Miscarriage | |
| 98 | 8 weeks | 61 | 55500 | 129 | 64000 | 176 | 98 | 9 weeks | 65 | 34700 | 44 | 10340 | 23 | Miscarriage | |
| 99 | 8 weeks | 62 | 11320 | 116 | 10000 | 150 | Miscarriage | 99 | 9 weeks | 66 | 6589 | 44 | 578 | 6 | Miscarriage |
| 100 | 9 weeks | 63 | 102000 | 192.5 | 12600 | 200 | 100 | 9 weeks | 66 | 43200 | 136 | 116000 | 200 | ||
| 101 | 9 weeks | 64 | 243000 | 200 | 340000 | ＞200 | 101 | 9 weeks | 68 | 9860 | 56 | 5670 | 34 | Miscarriage | |
| 102 | 9 weeks | 64 | 124000 | 200 | 33150 | Miscarriage | 102 | 9 weeks | 68 | 32400 | 74 | 54000 | 89 | Miscarriage | |
| 103 | 9 weeks | 64 | 23450 | 200 | 28000 | 198 | 103 | 9 weeks | 68 | 10578 | 12 | 10500 | 12 | Miscarriage | |
| 104 | 9 weeks | 65 | 114100 | 83 | 136790 | ＞200 | 104 | 9 weeks | 69 | 116000 | 145 | 236000 | ＞200 | ||
| 105 | 9 weeks | 65 | 11200 | 126 | 120000 | 200 | 105 | 9 weeks | 70 | 20089 | 32 | 11700 | 7 | Miscarriage | |
| 106 | 9 weeks | 65 | 23005 | 89 | 50000 | 156 | 106 | 9 weeks | 71 | 23480 | 55 | 6668 | 9 | Miscarriage | |
| 107 | 9 weeks | 65 | 20000 | 200 | 18000 | 180 | Miscarriage | 107 | 9 weeks | 71 | 7960 | 58 | 134780 | 159 | |
| 108 | 9 weeks | 66 | 53000 | 115 | 98700 | 123 | 108 | 9 weeks | 71 | 10030 | 67 | 23600 | 110 | Miscarriage | |
| 109 | 9 weeks | 67 | 23000 | 126 | 345780 | 188 | 109 | 9 weeks | 74 | 120000 | 170 | 230000 | ＞200 | ||
| 110 | 9 weeks | 68 | 18200 | 192 | 34000 | ＞200 | 110 | 9 weeks | 74 | 22300 | 11 | 21000 | 11 | Miscarriage | |
| 111 | 9 weeks | 68 | 55000 | 162 | 55000 | 150 | Miscarriage | 111 | 9 weeks | 75 | 10000 | 200 | 10020 | 200 | Miscarriage |
| 112 | 9 weeks | 68 | 40000 | 136 | 60800 | 189 | 112 | 10 weeks | 79 | 6789 | 3 | 5000 | 3 | Miscarriage | |
| 113 | 9 weeks | 69 | 80000 | 200 | 55500 | 200 | 113 | 10 weeks | 89 | 57300 | 44 | 46388 | 40 | Miscarriage | |
| 114 | 9 weeks | 70 | 37600 | 200 | 86660 | ＞200 | 114 | 10 weeks | 89 | 83670 | 120 | 103700 | 159 | Miscarriage |
| 115 | 9 weeks | 70 | 90000 | 145 | 156800 | 200 | 115 | 10 weeks | 89 | 110000 | 200 | 340000 | ＞200 | ||
| 116 | 9 weeks | 71 | 63500 | ＞200 | 103800 | ＞200 | 116 | 10 weeks | 90 | 55890 | 66 | 36700 | 23 | Miscarriage | |
| 117 | 9 weeks | 71 | 4700 | 200 | 340 | 50 | Miscarriage | 117 | 10 weeks | 90 | 23400 | 68 | 45700 | 130 | Miscarriage |
| 118 | 9 weeks | 71 | 260 | 22 | 430 | 13 | Miscarriage | ||||||||
| 119 | 9 weeks | 72 | 103500 | 200 | 197800 | ＞200 | |||||||||
| 120 | 9 weeks | 72 | 54600 | 187 | 114500 | ＞200 | |||||||||
| 121 | 9 weeks | 73 | 80000 | 175 | 167800 | 200 | |||||||||
| 122 | 9 weeks | 74 | 56780 | 200 | 34600 | 15 | Miscarriage | ||||||||
| 123 | 10 weeks | 77 | 35800 | 175 | 104500 | 200 | |||||||||
| 124 | 10 weeks | 77 | 68750 | 200 | 152480 | ＞200 | |||||||||
| 125 | 10 weeks | 89 | 20200 | 42.5 | 24000 | 129 | |||||||||
| 126 | 10 weeks | 89 | 35600 | 88 | 12400 | 55 | Miscarriage |
126 examples are taken Chinese medicine provided by the invention (treatment group) and 117 examples and are given Progesterone (matched group) and prevent miscarriage as can be seen from the above table, and two groups of efficacy results: the treatment group is cured 97 examples, and the rate of preventing miscarriage is 76.98%; Matched group is cured 51 examples, the rate 43.59% of preventing miscarriage.
Following table 1 for the responder that prevents miscarriage treat before and after HCG, LH dynamic change value comparison sheet (x ± S), after can finding out obviously that from table 1 patient adopts Chinese medicine compound provided by the invention, HCG, LH all have stable or significantly raise, clinical symptoms is also improved synchronously and is alleviated, and B ultrasonic detects and fetus heart beating all occurs by the B ultrasonic detection of dynamic after no fetal rhythm person treats before the treatment.
Table 1
| Pregnant week | n | The treatment group | n | Matched group | ||||||
| HCG(mIU/mL) | LH(mIU/mL) | HCG(mIU/mL) | LH(mIU/mL) | |||||||
| Before the treatment | After the treatment | Before the treatment | After the treatment | Before the treatment | After the treatment | Before the treatment | After the treatment | |||
| 5 | 24 | 5404±5203 | 24708±29651* | 93±74 | 170±38** | 12 | 4541±4326 | 27820±50168 | 66±46 | 155±51** |
| 6 | 30 | 12329±15343 | 23940±21933 ** | 109±69 | 178±31** | 15 | 49433±89593 | 130309±129476* | 102±57 | 191±20** |
| 7 | 14 | 16032±15947 | 23623±22658 | 114±78 | 175±43* | 11 | 12201±19099 | 77109±98451 | 58±39 | 176±36** |
| 8 | 9 | 12427±16538 | 23836±24130 | 100±54 | 180±21** | 5 | 62880±40662 | 119560±74106 | 155±67 | 196±10* |
| 9 | 17 | 68244±55796 | 124090±97109 * | 163±42 | 191±21* | 7 | 140680±184185 | 248069±269845 | 147±50 | 194±15* |
| 10 | 3 | 41583±24786 | 93660±64922 | 139±85 | 176±41 | 1 | 110000 | 340000 | 200 | 200 |
Following table 2 for the Aborter treat before and after HCG, LH dynamic change value comparison sheet (x ± S), after can finding out obviously that as can be seen from Table 2 the patient adopts Chinese medicine compound provided by the invention, abortion ratio is starkly lower than matched group: treatment group 52 example miscarriages 24 examples, abortion ratio 46.15%; Matched group 49 example miscarriages 45 routine abortions ratio 91.85%.
Table 2
| Pregnant week | n | The treatment group | n | Matched group | ||||||
| HCG(mIU/mL) | LH(mIU/mL) | HCG(mIU/mL) | LH(mIU/mI) | |||||||
| Before the treatment | After the treatment | Before the treatment | After the treatment | Before the treatment | After the treatment | Before the treatment | After the treatment | |||
| 5 | 5 | 1276±841 | 621±435 | 13±6 | 11±12 | 16 | 1359±844 | 1411±1543 | 30±25 | 27±32 |
| 6 | 8 | 3854±3663 | 1625±2114 | 63±57 | 58±74 | 17 | 7507±9566 | 19971±40612 | 76±56 | 69±65 |
| 7 | 7 | 8076±14499 | 7624±14770 | 80±84 | 75±87 | 9 | 17822±31934 | 8806±6635 | 85±34 | 93±64 |
| 8 | 2 | 6100±7382 | 5110±6916 | 91±36 | 83±95 | 5 | 21658±33035 | 23492±44158 | 60±72 | 59±84 |
| 9 | 6 | 43457±46295 | 23587±21482 | 164±71 | 101±85 | 14 | 22420±15740 | 19126±18767 | 77±64 | 65±73 |
| 10 | 1 | 35600 | 12400 | 88 | 55 | 5 | 45410±30377 | 47498±35657 | 60±42 | 71±69 |
*P≤0.05 is meaningful,
*P≤0.001 significance.
The specific embodiment
Embodiment 1:
Prescription: Radix Dipsaci 10g, Semen Cuscutae 10g, Herba Taxilli 10g, Caulis Perillae 10g, Fructus Amomi 10g (back down), Radix Paeoniae Alba 10g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Fructus Corni 10g, Fructus Alpiniae Oxyphyllae 10g, Radix Astragali Preparata 10g, Radix Pseudostellariae 10g, Cacumen Platycladi preparata 10g, charred Radix Sanguisorbae 10g, charred RADIX RUBIAE 10g, Radix Angelicae Sinensis 5g, Herba Leonuri 5g, Ophicalcitum 2g (taking after mixing it with water), Radix Boehmeriae 5g, Semen Euryales 5g, Radix Glycyrrhizae Preparata 5.5g.
The decoction method of described decoction is: fry in shallow oil first with cold water, amount of water is 3 to 4 times of above-mentioned Chinese medicine total amount, soak half an hour after, add Fructus Amomi after 25 minutes at a simmer and fried in shallow oil again 5 minutes, leach medicine juice; Secondary is fried in shallow oil adding cold water, and amount of water is 2 to 3 times of above-mentioned Chinese medicine total amount, fries in shallow oil half an hour, leaches medicine juice for twice and mixes even the branch 2 times or 3-5 time, and potion on the one, warm and Ophicalcitum all part take orally simultaneously, avoid cold and uncooked food, and 3 days one courses of treatment, obey the 2-3 course of treatment altogether.
Embodiment 2:
Prescription: Radix Dipsaci 9g, Semen Cuscutae 9g, Herba Taxilli 9g, Caulis Perillae 9g, Fructus Amomi 9g (back down), Radix Paeoniae Alba 9g, Rhizoma Atractylodis Macrocephalae (parched) 9g, Fructus Corni 9g, Fructus Alpiniae Oxyphyllae 9g, Radix Astragali Preparata 9g, Radix Pseudostellariae 9g, Cacumen Platycladi preparata 9g, charred Radix Sanguisorbae 9g, charred RADIX RUBIAE 9g, Radix Angelicae Sinensis 4g, Herba Leonuri 4g, Ophicalcitum 1.5g (taking after mixing it with water), Radix Boehmeriae 4g, Semen Euryales 4g, Radix Glycyrrhizae Preparata 5g.
The decoction method of described decoction is: fry in shallow oil first with cold water, amount of water is 3 to 4 times of above-mentioned Chinese medicine total amount, soak half an hour after, add Fructus Amomi after 25 minutes at a simmer and fried in shallow oil again 5 minutes, leach medicine juice; Secondary is fried in shallow oil adding cold water, and amount of water is 2 to 3 times of above-mentioned Chinese medicine total amount, fries in shallow oil half an hour, leaches medicine juice for twice and mixes even the branch 2 times or 3-5 time, and potion on the one, warm and Ophicalcitum all part take orally simultaneously, avoid cold and uncooked food, and 3 days one courses of treatment, obey the 2-3 course of treatment altogether.
Embodiment 3:
Prescription: Radix Dipsaci 12g, Semen Cuscutae 12g, Herba Taxilli 12g, Caulis Perillae 12g, Fructus Amomi 12g (back down), Radix Paeoniae Alba 12g, Rhizoma Atractylodis Macrocephalae (parched) 12g, Fructus Corni 12g, Fructus Alpiniae Oxyphyllae 12g, Radix Astragali Preparata 12g, Radix Pseudostellariae 12g, Cacumen Platycladi preparata 12g, charred Radix Sanguisorbae 12g, charred RADIX RUBIAE 12g, Radix Angelicae Sinensis 6g, Herba Leonuri 6g, Ophicalcitum 3g (taking after mixing it with water), Radix Boehmeriae 6g, Semen Euryales 6g, Radix Glycyrrhizae Preparata 6g.
The decoction method of described decoction is: fry in shallow oil first with cold water, amount of water is 3 to 4 times of above-mentioned Chinese medicine total amount, soak half an hour after, add Fructus Amomi after 25 minutes at a simmer and fried in shallow oil again 5 minutes, leach medicine juice; Secondary is fried in shallow oil adding cold water, and amount of water is 2 to 3 times of above-mentioned Chinese medicine total amount, fries in shallow oil half an hour, leaches medicine juice for twice and mixes even the branch 2 times or 3-5 time, and potion on the one, warm and Ophicalcitum all part take orally simultaneously, avoid cold and uncooked food, and 3 days one courses of treatment, obey the 2-3 course of treatment altogether.
Embodiment 4:
Prescription: Radix Dipsaci 8g, Semen Cuscutae 8g, Herba Taxilli 8g, Caulis Perillae 8g, Fructus Amomi 8g (back down), Radix Paeoniae Alba 8g, Rhizoma Atractylodis Macrocephalae (parched) 8g, Fructus Corni 8g, Fructus Alpiniae Oxyphyllae 8g, Radix Astragali Preparata 8g, Radix Pseudostellariae 8g, Cacumen Platycladi preparata 8g, charred Radix Sanguisorbae 8g, charred RADIX RUBIAE 8g, Radix Angelicae Sinensis 3.5g, Herba Leonuri 3.5g, Ophicalcitum 1.5g (taking after mixing it with water), Radix Boehmeriae 3.5g, Semen Euryales 3.5g, Radix Glycyrrhizae Preparata 4g.
The decoction method of described decoction is: fry in shallow oil first with cold water, amount of water is 3 to 4 times of above-mentioned Chinese medicine total amount, soak half an hour after, add Fructus Amomi after 25 minutes at a simmer and fried in shallow oil again 5 minutes, leach medicine juice; Secondary is fried in shallow oil adding cold water, and amount of water is 2 to 3 times of above-mentioned Chinese medicine total amount, fries in shallow oil half an hour, leaches medicine juice for twice and mixes even the branch 2 times or 3-5 time, and potion on the one, warm and Ophicalcitum all part take orally simultaneously, avoid cold and uncooked food, and 3 days one courses of treatment, obey the 2-3 course of treatment altogether.
Embodiment 5:
Prescription: Radix Dipsaci 11g, Semen Cuscutae 11g, Herba Taxilli 11g, Caulis Perillae 11g, Fructus Amomi 11g (back down), Radix Paeoniae Alba 11g, Rhizoma Atractylodis Macrocephalae (parched) 11g, Fructus Corni 11g, Fructus Alpiniae Oxyphyllae 11g, Radix Astragali Preparata 11g, Radix Pseudostellariae 11g, Cacumen Platycladi preparata 11g, charred Radix Sanguisorbae 11g, charred RADIX RUBIAE 11g, Radix Angelicae Sinensis 5g, Herba Leonuri 5g, Ophicalcitum 2g (taking after mixing it with water), Radix Boehmeriae 5g, Semen Euryales 5g, Radix Glycyrrhizae Preparata 6g.
The decoction method of described decoction is: fry in shallow oil first with cold water, amount of water is 3 to 4 times of above-mentioned Chinese medicine total amount, soak half an hour after, add Fructus Amomi after 25 minutes at a simmer and fried in shallow oil again 5 minutes, leach medicine juice; Secondary is fried in shallow oil adding cold water, and amount of water is 2 to 3 times of above-mentioned Chinese medicine total amount, fries in shallow oil half an hour, leaches medicine juice for twice and mixes even the branch 2 times or 3-5 time, and potion on the one, warm and Ophicalcitum all part take orally simultaneously, avoid cold and uncooked food, and 3 days one courses of treatment, obey the 2-3 course of treatment altogether.
Chinese medicine in the foregoing description can be made into decoction, pill, powder, unguentum, syrup, tablet, granule or powder preparation to be taken after being infused in boiling water or capsule, and pill can be honeyed pill, the watered pill, paste pill or concentrated pill, and unguentum can be fluid extract, extractum or soft extract.
Claims (6)
1. Chinese medicine for the treatment of threatened abortion, it is characterized in that: it comprises the raw material of following parts by weight: Radix Dipsaci 9-12g, Semen Cuscutae 9-12g, Herba Taxilli 9-12g, Caulis Perillae 9-12g, Fructus Amomi 9-12g (back down), Radix Paeoniae Alba 9-12g, Rhizoma Atractylodis Macrocephalae (parched) 9-12g, Fructus Corni 9-12g, Fructus Alpiniae Oxyphyllae 9-12g, Radix Astragali Preparata 9-12g, Radix Pseudostellariae 9-12g, Cacumen Platycladi preparata 9-12g, charred Radix Sanguisorbae 9-12g, charred RADIX RUBIAE 9-12g, Radix Angelicae Sinensis 3-6g, Herba Leonuri 3-6g, Ophicalcitum 2-3g (taking after mixing it with water), Radix Boehmeriae 3-6g, Semen Euryales 3-6g, Radix Glycyrrhizae Preparata 3-6g.
2. a kind of Chinese medicine for the treatment of threatened abortion as claimed in claim 1, it is characterized in that: it comprises the raw material of following parts by weight: Radix Dipsaci 10g, Semen Cuscutae 10g, Herba Taxilli 10g, Caulis Perillae 10g, Fructus Amomi 10g (back down), Radix Paeoniae Alba 10g, Rhizoma Atractylodis Macrocephalae (parched) 10g, Fructus Corni 10g, Fructus Alpiniae Oxyphyllae 10g, Radix Astragali Preparata 10g, Radix Pseudostellariae 10g, Cacumen Platycladi preparata 10g, charred Radix Sanguisorbae 10g, charred RADIX RUBIAE 10g, Radix Angelicae Sinensis 5g, Herba Leonuri 5g, Ophicalcitum 2g (taking after mixing it with water), Radix Boehmeriae 5g, Semen Euryales 5g, Radix Glycyrrhizae Preparata 5.5g.
3. a kind of Chinese medicine for the treatment of threatened abortion as claimed in claim 1 or 2, it is characterized in that: described Chinese medicine can be made into decoction, pill, powder, unguentum, syrup, tablet, granule or powder preparation to be taken after being infused in boiling water or capsule.
4. a kind of Chinese medicine for the treatment of threatened abortion as claimed in claim 3 is characterized in that: described pill can be honeyed pill, the watered pill, paste pill or concentrated pill.
5. a kind of Chinese medicine for the treatment of threatened abortion as claimed in claim 3 is characterized in that: described unguentum can be fluid extract, extractum or soft extract.
6. a kind of Chinese medicine for the treatment of threatened abortion as claimed in claim 3, it is characterized in that: the decoction method of described decoction is: fry in shallow oil first with cold water, amount of water is 3 to 4 times of above-mentioned Chinese medicine total amount, soak half an hour after, add Fructus Amomi after 25 minutes at a simmer and fried in shallow oil again 5 minutes, leach medicine juice; Secondary is fried in shallow oil adding cold water, and amount of water is 2 to 3 times of above-mentioned Chinese medicine total amount, fries in shallow oil half an hour, leaches medicine juice for twice and mixes even the branch 2 times or 3-5 time, and potion on the one, warm and Ophicalcitum all part take orally simultaneously, avoid cold and uncooked food, and 3 days one courses of treatment, obey the 2-3 course of treatment altogether.
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| CNB2006100797601A CN100444886C (en) | 2006-05-13 | 2006-05-13 | A Chinese medicine for treating threatened abortion |
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| CNB2006100797601A CN100444886C (en) | 2006-05-13 | 2006-05-13 | A Chinese medicine for treating threatened abortion |
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| CN1879838A true CN1879838A (en) | 2006-12-20 |
| CN100444886C CN100444886C (en) | 2008-12-24 |
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103041102A (en) * | 2012-12-17 | 2013-04-17 | 青岛盛瀚色谱技术有限公司 | Traditional Chinese medicine composition for treating threatened abortion |
| CN103623089A (en) * | 2013-11-27 | 2014-03-12 | 贵州桑杨生物科技开发有限公司 | Health-maintaining fetus-protecting traditional Chinese medicine composition and preparation method thereof |
| CN104824454A (en) * | 2015-05-18 | 2015-08-12 | 新希望六和饲料股份有限公司 | Sow formula feed and preparation method thereof |
| CN105213926A (en) * | 2015-11-11 | 2016-01-06 | 浙江锦天生物科技有限公司 | A kind of Chinese medicine composition and preparation method for the treatment of threatened abortion |
| CN110507799A (en) * | 2019-09-11 | 2019-11-29 | 熊润之 | A kind of medicine pill formula and preparation method improving pelvic cavity environment |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1068964A (en) * | 1988-11-03 | 1993-02-17 | 孙剑秋 | The manufacturing process flow of kangtaiwan |
-
2006
- 2006-05-13 CN CNB2006100797601A patent/CN100444886C/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103041102A (en) * | 2012-12-17 | 2013-04-17 | 青岛盛瀚色谱技术有限公司 | Traditional Chinese medicine composition for treating threatened abortion |
| CN103623089A (en) * | 2013-11-27 | 2014-03-12 | 贵州桑杨生物科技开发有限公司 | Health-maintaining fetus-protecting traditional Chinese medicine composition and preparation method thereof |
| CN103623089B (en) * | 2013-11-27 | 2015-07-22 | 贵州桑杨生物科技开发有限公司 | Health-maintaining fetus-protecting traditional Chinese medicine composition and preparation method thereof |
| CN104824454A (en) * | 2015-05-18 | 2015-08-12 | 新希望六和饲料股份有限公司 | Sow formula feed and preparation method thereof |
| CN105213926A (en) * | 2015-11-11 | 2016-01-06 | 浙江锦天生物科技有限公司 | A kind of Chinese medicine composition and preparation method for the treatment of threatened abortion |
| CN110507799A (en) * | 2019-09-11 | 2019-11-29 | 熊润之 | A kind of medicine pill formula and preparation method improving pelvic cavity environment |
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| Publication number | Publication date |
|---|---|
| CN100444886C (en) | 2008-12-24 |
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