CN105727234A - Traditional Chinese medicine composition for treating alopecia as well as preparation method and application of traditional Chinese medicine composition - Google Patents
Traditional Chinese medicine composition for treating alopecia as well as preparation method and application of traditional Chinese medicine composition Download PDFInfo
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A61K2236/30—Extraction of the material
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- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The invention provides a traditional Chinese medicine composition for treating alopecia as well as a preparation method and an application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 5-20 parts of rhodiola rosea, 2-9 parts of cynomorium songaricum, 4-15 parts of grape fruits, 2-9 parts of polygonum multiflorum, 1-7 parts of lucid ganoderma and 1-10 parts of fresh ginger. The invention further provides hair cosmetics containing the traditional Chinese medicine composition and hair-washing accessories for treating alopecia.
Description
Technical field
The present invention relates to the Chinese medicine composition of a kind of hair growth, particularly to one by Radix Rhodiolae, Herba Cynomorii,
The Fructus Sapindi Mukouossi, Radix Polygoni Multiflori, Ganoderma and Rhizoma Zingiberis Recens are Chinese medicine composition of making of raw material and preparation method and application.
Background technology
Use Chinese medicine well known in hair growth product.It is surprising that several Chinese medicine composition it
After resultant effect, the effect being usually each used alone from it is different.Radix Rhodiolae, as a kind of famous and precious
Medicinal plants, in most cases people only understand the effectiveness that it is for oral administration.Same, Herba Cynomorii is usually used as one
Plant the kidney invigorating, beneficial medicine use for oral administration smart, that moisturize.Chinese patent application CN104383114 A discloses one
Plant containing Fructus Lycii, Radix Angelicae Sinensis, Folium Ginkgo and the mixture of Herba Menthae, the most also can contain Radix Polygoni Multiflori, as anti-
Alopecia Chinese medicine composition.Chinese patent application CN101513503 B discloses a kind of hair-growing and anti-hair loss Chinese drug-treated group
Compound, including following traditional Chinese medicines and weight portion: the ripe Radix Polygoni Multiflori 5~8 parts, Radix Angelicae Sinensis 5~8 parts, Radix Rehmanniae 8~10
Part, Radix Rehmanniae Preparata 8~10 parts, Semen Cuscutae 5~8 parts, Semen Oroxyli 5~8 parts, Radix Achyranthis Bidentatae 5~8 parts, Fructus Ligustri Lucidi
8~10 parts, Radix Arnebiae (Radix Lithospermi) 3~6 parts, Rhizoma Chuanxiong 3~6 parts, angelica 3~6 parts, Radix Saposhnikoviae 3~6 parts, tomorrow
Fiber crops 3~6 parts, Herba Ecliptae 8~10 parts, Herba Agrimoniae 8~10 parts, Poria 5~8 parts, Rhizoma Drynariae 8~10
Part, Cortex Dictamni 5~8 parts, Haematitum 12~20 parts, Herba Taxilli 8~10 parts, unpeeled CORTEX MOUTAN 3~6 parts are black
Fructus Mori 8~10 parts.The advantage of said composition is effectively to treat early whitening of hair, alopecia, alopecia areata and eyebrow
Coming off, but its selected Chinese crude drug kind is too much, curative effect is indefinite.
Summary of the invention
It is an object of the invention to overcome in prior art the curative effect existing for hair growth product indefinite on
State deficiency, it is provided that the Chinese medicine composition of a kind of hair growth.
Another object of the present invention is to propose the extracting method of a kind of above-mentioned Chinese medicine composition active component.
The third object of the present invention is the hair cosmetic combination proposing to utilize above-mentioned Chinese medicine extract to prepare
Thing.
The fourth object of the present invention is to propose the optimal preparation method of a kind of above-mentioned cosmetic composition for hair.
The invention thinking of the present invention is: the present invention is effectively combined China's Traditional Chinese Medicine theory, according to monarch,
Minister, the traditional Chinese medical science prescription thought helped, make, by Chinese crude drug Radix Rhodiolae, Herba Cynomorii, the Fructus Sapindi Mukouossi, Radix Polygoni Multiflori, Ganoderma
Compound with Rhizoma Zingiberis Recens, and with composite traditional Chinese medicine extract for primary efficacy additive, other being aided with in cosmetics become
Point have developed a can the Chinese medicine shampoo of hair growth.Periodically have one's hair wash with it, can be raw with hair follicle stimulating
Long, scalp cells can be activated, and strengthen scalp blood circulation, have blood-activating and qi-promoting, treatment alopecia and
Control oil effect, particularly has significant curative effect to seborrheic alopecia.
The present invention selects Radix Rhodiolae, Herba Cynomorii, the Fructus Sapindi Mukouossi, Radix Polygoni Multiflori, Ganoderma and the combination of Rhizoma Zingiberis Recens Six-element Chinese crude drug,
Thus effectively play effect of hair growth.Six medicaments effect brief introduction is as follows:
Radix Rhodiolae, nature and flavor are cold, sweet, puckery.Return lung meridian.QI invigorating lung heat clearing, Fructus Alpiniae Oxyphyllae nourishes heart, hemostasis with astringents, dissipates
Stagnation resolvation is swollen.Controlling deficiency of vital energy and physically weak, after being ill fear of cold, shortness of breath and fatigue, cough due to lung-heat, spitting of blood, leucorrhea is suffered from diarrhoea, falls
Play damage.
Herba Cynomorii, nature and flavor are sweet and puckery, control the moon and decline Sanguis Draxonis;The weak deficiency of YIN of gas, dripping not to the utmost;Soreness of the waist and knees, tired
Unable;Fear of cold is the coldest, limbs pain;Menoxenia, cold womb leukorrhagia;Insomnia forgetfulness, alopecia is the whitest, stomach
Acid ulcer.
The Fructus Sapindi Mukouossi, mildly bitter flavor, property are flat.Spleen reinforcing stomach invigorating, blood fat-reducing blood pressure-decreasing, dredging collateral expelling wind and removing dampness, benefiting qi and nourishing blood,
Moistening the lung and resolving the phlegm, the benefit gate of vitality, place three is burnt, warming the lung intestine moistening.Controlling deficiency and coldness to breath with cough, waist foot heavily aches, trusted subordinate's colic,
Dysentery hemorrhoidal hamorrhage.
Radix Polygoni Multiflori, bitter sweet puckery, warm in nature, enter liver, kidney channel.Nourishing the blood and yin, loosening bowel to relieve constipation, preventing the attack (or recurrence) of malaria, dispel the wind,
Removing toxic substances.Main blood deficiency Light-headedness;Cardiopalmus;Insomnia;The soreness of the waist and knees of the hepatic and renal YIN deficiency;Early whitening of beard and hair;Tinnitus;
Seminal emission;Dryness of the intestine constipation;Chronic malaria body is empty;Rubella pruritus;Carbuncle sore;Scrofula;Hemorrhoid.
Ganoderma, property puts down, sweet in the mouth, enters heart channel, can reinforcing the heart blood, the benefit motive, tranquilizing mind, control insufficiency of vital energy and blood,
Malaise caused by lack of preservation of spirit, have a sleepless night, palpitate with fear, dreaminess, forgetful, the tired Mental fatigue of body, lack of appetite.
Rhizoma Zingiberis Recens, property heat, acrid in the mouth.Return spleen, stomach, the heart, lung meridian.Warming middle-JIAO, recuperating depleted YANG, warming the lung to resolve fluid-retention, invigorate blood circulation
Cold relieving.
In order to realize foregoing invention purpose, the invention provides techniques below scheme:
The Chinese medicine composition of a kind of hair growth, it is characterised in that described compositions is by following weight
Crude drug make: Radix Rhodiolae 5-20 part, Herba Cynomorii 2-9 part, Fructus Sapindi Mukouossi 4-15 part, Radix Polygoni Multiflori 2-9 part,
Ganoderma 1-7 part, Rhizoma Zingiberis Recens 1-10 part.
Applicant finds through many experiments, and Chinese medicine composition of the present invention is by the raw material of above-mentioned weight
Make, can preferably play the synergistic function of each raw material components, not only can effective hair growth, with
Time instant effect, dosage is little, has no side effect.
Preferably, described compositions is made up of the crude drug of following weight: Radix Rhodiolae 5-15 part, lock
Sun 3-7 part, Fructus Sapindi Mukouossi 5-12 part, Radix Polygoni Multiflori 3-8 part, Ganoderma 2-6 part, Rhizoma Zingiberis Recens 2-8 part.
It is further preferred that described compositions is made up of the raw material of following weight proportion: Radix Rhodiolae 10-12 part,
Herba Cynomorii 5-6 part, Fructus Sapindi Mukouossi 6-10 part, Radix Polygoni Multiflori 5-8 part, Ganoderma 3-6 part, Rhizoma Zingiberis Recens 5-7 part.
The most preferably, described compositions is made up of the raw material of following weight proportion: Radix Rhodiolae 12 parts, Herba Cynomorii
6 parts, the Fructus Sapindi Mukouossi 8 parts, Radix Polygoni Multiflori 6 parts, Ganoderma 6 parts, 6 parts of Rhizoma Zingiberis Recens.
By above preferred, the curative effect of Chinese medicine composition can be improved further.
The Chinese medicine extract of a kind of hair growth, described extract is carried through Chinese materia medica routine by combinations of the above thing
Access method extracts and obtains.
Above-mentioned Chinese medicine extract can be prepared as various hair washing in conjunction with hair cosmetic field customary adjuvant and produce
Product, such as shampoo, hair conditioner, shampoo etc..
A kind of above-mentioned Chinese medicine composition prepare extract method, specifically comprise the following steps that
(1) each crude drug is weighed according to said ratio;
(2) described crude drug is separately added into 50~70% ethanol of 8~10 times of volumes, reflux, extract, three times,
Extraction time is respectively 2.0h, 1.5h, 1.5h, filters, merges 3 filtrates;
(3) by described filtrate recycling ethanol and concentrate, then by the concentrated solution mix homogeneously of each crude drug, it is dried,
Obtain activity extract.
Six kinds of concentrated solutions are mixed after first being concentrated by the alcohol extract of crude drug by above-mentioned steps again, made
The effective ingredient of standby activity extract is higher.
Preparation method of the present invention can effectively extract the effective ingredient in each crude drug so that it is more preferably
Play Synergistic effect.
The cosmetic composition for hair of a kind of hair growth, described cosmetic composition for hair is by following quality hundred
The raw material of proportion by subtraction is made:
Described Chinese medicine extract is the Chinese medicine extract that said method prepares.
A kind of method preparing above-mentioned cosmetic composition for hair, it is characterised in that described in specifically comprise the following steps that
(1) Chinese medicine extract, Coco-Glucoside are uniformly mixed 5-15min at 65-75 DEG C, exist afterwards
Put 20-30min at 65-75 DEG C, form mixed liquor;
(2) mixed liquor in step (1) is heated to 75-85 DEG C, and adds melon glue Hydroxyproyl Trimethyl
Chlorination and deionized water are stirred, and stir 10-12min;
(3), after being cooled to 45-50 DEG C, add preservative, i.e. obtain after stirring.
The shampoo of a kind of hair growth, described shampoo is prepared through said method by above-mentioned raw material.
Compared with prior art, beneficial effects of the present invention:
(1) the various raw medicinal materials used by the present invention are and meet country or Chinese crude drug that provincial standard specifies.
Chinese medicine composition for hair growth of the present invention, according to " hair is the sign of blood condition " of Chinese medicine, uses
Based on replenishing YIN and blood, clearing away heat and cooling blood, it is aided with the means such as promoting flow of QI and blood, expelling pathogenic wind from the body surface, to reach to adjust head
The purpose of portion's QI-blood circulation situation, in conjunction with clinical practice, filters out Radix Rhodiolae, lock from Chinese medicine material treasure-house
Sun, the Fructus Sapindi Mukouossi, Radix Polygoni Multiflori, Ganoderma and the pure purification of tcm of Rhizoma Zingiberis Recens Six-element form, and regulate the weight of each raw material
Part proportioning, makes to play between each raw material the effect of Synergistic, can effective hair growth.
(2) all the components of the present invention is natural plant composition, and without any chemical addition agent, products obtained therefrom is green
Color safety and Health, effect is notable.
Detailed description of the invention
Below in conjunction with test example and detailed description of the invention, the present invention is described in further detail.But should be by
This is interpreted as that the scope of the above-mentioned theme of the present invention is only limitted to below example, all real based on present invention institute
Existing technology belongs to the scope of the present invention.
Embodiment 1
The Chinese medicine composition of the hair growth described in the present embodiment, is made up of the raw material of following weight: Radix Rhodiolae
12 parts, Herba Cynomorii 6 parts, the Fructus Sapindi Mukouossi 8 parts, Radix Polygoni Multiflori 6 parts, Ganoderma 6 parts, 6 parts of Rhizoma Zingiberis Recens.
It is as follows that described Chinese medicine composition prepares alcohol extract method: the raw material of above-mentioned weight is separately added into 9
70% ethanol of times volume, reflux, extract, three times, extraction time is respectively 2.0h, 1.5h, 1.5h, filters,
Merge 3 filtrates, by each concentrated solution mix homogeneously after reclaiming ethanol and concentrating, be dried, obtain active extraction
Thing.
The cosmetic composition for hair of the hair growth described in the present embodiment, by the raw material of following mass percent
Make: Chinese medicine extract 10%, Coco-Glucoside 25%, guar hydroxypropyltrimonium chloride 3%,
Preservative 0.05%, surplus is deionized water
The preparation method of described cosmetic composition for hair, comprises the following steps:
(1) Chinese medicine extract, Coco-Glucoside are uniformly mixed 10min at 70 DEG C, afterwards at 70 DEG C
Lower storing 25min, forms mixed liquor;
(2) mixed liquor in step (1) is heated to 80 DEG C, and adds melon glue Hydroxyproyl Trimethyl chlorination
It is stirred with deionized water, stirs 10min;
(3), after being cooled to 45 DEG C, add preservative, i.e. obtain after stirring.
Embodiment 2
The Chinese medicine composition of the hair growth described in the present embodiment, is made up of the raw material of following weight: Radix Rhodiolae 5
Part, Herba Cynomorii 2 parts, the Fructus Sapindi Mukouossi 4 parts, Radix Polygoni Multiflori 2 parts, Ganoderma 1 part, 1 part of Rhizoma Zingiberis Recens.
It is as follows that described Chinese medicine composition prepares alcohol extract method: is separately added into by the raw material of above-mentioned weight
70% ethanol of 10 times of volumes, reflux, extract, three times, extraction time is respectively 2.0h, 1.5h, 1.5h, mistake
Filter, merges 3 filtrates, by each concentrated solution mix homogeneously after reclaiming ethanol and concentrating, is dried, gets product.
The present embodiment prepares the raw material dosage of the hair cosmetic of hair growth and preparation process with embodiment 1.
Embodiment 3
The Chinese medicine composition of the hair growth described in the present embodiment, is made up of the raw material of following weight: Radix Rhodiolae
20 parts, Herba Cynomorii 9 parts, the Fructus Sapindi Mukouossi 15 parts, Radix Polygoni Multiflori 9 parts, Ganoderma 7 parts, 10 parts of Rhizoma Zingiberis Recens.
It is as follows that described Chinese medicine composition prepares alcohol extract method: the raw material of above-mentioned weight is separately added into 9
60% ethanol of times volume, reflux, extract, three times, extraction time is respectively 2.0h, 1.5h, 1.5h, filters,
Merge 3 filtrates, by each concentrated solution mix homogeneously after reclaiming ethanol and concentrating, be dried, get product.
The present embodiment prepares the raw material dosage of the hair cosmetic of hair growth and preparation process with embodiment 1.
Embodiment 4
The Chinese medicine composition of the hair growth described in the present embodiment, is made up of the raw material of following weight: Radix Rhodiolae
11 parts, Herba Cynomorii 6 parts, the Fructus Sapindi Mukouossi 8 parts, Radix Polygoni Multiflori 7 parts, Ganoderma 5 parts, 6 parts of Rhizoma Zingiberis Recens.
It is as follows that described Chinese medicine composition prepares alcohol extract method: is separately added into by the raw material of above-mentioned weight
50% ethanol of 10 times of volumes, reflux, extract, three times, extraction time is respectively 2.0h, 1.5h, 1.5h, mistake
Filter, merges 3 filtrates, by each concentrated solution mix homogeneously after reclaiming ethanol and concentrating, is dried, gets product.
The present embodiment prepares the raw material dosage of the hair cosmetic of hair growth and preparation process with embodiment 1.
Comparative example 1
The Chinese medicine composition of the hair growth described in the present embodiment, is made up of the raw material of following weight: Herba Cynomorii 6
Part, the Fructus Sapindi Mukouossi 8 parts, Radix Polygoni Multiflori 6 parts, Ganoderma 6 parts, 6 parts of Rhizoma Zingiberis Recens.
It is as follows that described Chinese medicine composition prepares alcohol extract method: the raw material of above-mentioned weight is separately added into 9
70% ethanol of times volume, reflux, extract, three times, extraction time is respectively 2.0h, 1.5h, 1.5h, filters,
Merge 3 filtrates, by each concentrated solution mix homogeneously after reclaiming ethanol and concentrating, be dried, get product.
The present embodiment prepares the raw material dosage of the hair cosmetic of hair growth and preparation process with embodiment 1.
Comparative example 2
The Chinese medicine composition of the hair growth described in the present embodiment, is made up of the raw material of following weight: Radix Rhodiolae
12 parts, Radix Polygoni Multiflori 6 parts, Ganoderma 6 parts, 6 parts of Rhizoma Zingiberis Recens.
It is as follows that described Chinese medicine composition prepares alcohol extract method: the raw material of above-mentioned weight is separately added into 9
70% ethanol of times volume, reflux, extract, three times, extraction time is respectively 2.0h, 1.5h, 1.5h, filters,
Merge 3 filtrates, by each concentrated solution mix homogeneously after reclaiming ethanol and concentrating, be dried, get product.
The present embodiment prepares the raw material dosage of the hair cosmetic of hair growth and preparation process with embodiment 1.
Test example
Clinical 240 example volunteers are tested, age distribution scope be 16-50 year, be divided into 6 groups, respectively
Use above-mentioned prepared hair cosmetic, within everyone every 3 days, use once, according to therapeutic effect, use February
And observe, and determine using effect by following criterion of therapeutical effect.
Recovery from illness: patient's depilation phenomenon is wholly absent.
Effective: patient's depilation phenomenon has been alleviated.
Invalid: before and after patient's use, symptom is without improving.
Through clinical usage, 160 example test examples of the Chinese medicine composition of hair growth prepared by above-described embodiment 1-4
In, effective example is 144 examples, accounting 90%, and recovery from illness example is 128 examples, accounting 80%.
And in the 80 example test examples of the Chinese medicine composition for hair growth prepared of above-mentioned comparative example 1-2, have
Effect example is 48 examples, and accounting is only 60%, and recovery from illness example is 24 examples, and accounting is only 30%.Nothing during use
Patient scalp occurs or hair is uncomfortable and other side effect.
Claims (10)
1. the Chinese medicine composition of a hair growth, it is characterised in that described compositions is made up of the crude drug of following weight: Radix Rhodiolae 5-20 part, Herba Cynomorii 2-9 part, Fructus Sapindi Mukouossi 4-15 part, Radix Polygoni Multiflori 2-9 part, Ganoderma 1-7 part, Rhizoma Zingiberis Recens 1-10 part.
The Chinese medicine composition of a kind of hair growth the most according to claim 1, it is characterized in that, described compositions is made up of the crude drug of following weight: Radix Rhodiolae 5-15 part, Herba Cynomorii 3-7 part, Fructus Sapindi Mukouossi 5-12 part, Radix Polygoni Multiflori 3-8 part, Ganoderma 2-6 part, Rhizoma Zingiberis Recens 2-8 part.
The Chinese medicine composition of a kind of hair growth the most according to claim 2, it is characterized in that, described compositions is made up of the raw material of following weight proportion: Radix Rhodiolae 10-12 part, Herba Cynomorii 5-6 part, Fructus Sapindi Mukouossi 6-10 part, Radix Polygoni Multiflori 5-8 part, Ganoderma 3-6 part, Rhizoma Zingiberis Recens 5-7 part.
The Chinese medicine composition of a kind of hair growth the most according to claim 3, it is characterised in that described compositions is made up of the raw material of following weight proportion: Radix Rhodiolae 12 parts, Herba Cynomorii 6 parts, the Fructus Sapindi Mukouossi 8 parts, Radix Polygoni Multiflori 6 parts, Ganoderma 6 parts, 6 parts of Rhizoma Zingiberis Recens.
5. the Chinese medicine extract of a hair growth, it is characterised in that described extract is obtained through the extraction of Chinese materia medica general extraction methods by the compositions described in any one of claim 1-4.
6. the application in preparing hair cosmetic of the Chinese medicine extract described in claim 5.
7. the Chinese medicine composition described in a claim 1 prepare extract method, it is characterised in that specifically comprise the following steps that
(1) each crude drug is weighed according to the proportioning of any one of claim 1-4;
(2) described crude drug is separately added into 50~70% ethanol of 8~10 times of volumes, reflux, extract, three times, and extraction time is respectively 2.0h, 1.5h, 1.5h, filters, merges 3 filtrates;
(3) by described filtrate recycling ethanol and concentrate, then by the concentrated solution mix homogeneously of each crude drug, it is dried, obtains activity extract.
8. the cosmetic composition for hair of a hair growth, it is characterised in that described cosmetic composition for hair is made up of the raw material of following mass percent:
Chinese medicine extract
3-15%
Coco-Glucoside
10-30%
Guar hydroxypropyltrimonium chloride
1-5%
Preservative
0.01-0.3%
Deionized water
Surplus
Described Chinese medicine extract is extract described in claim 5 or the Chinese medicine extract of claim 7 preparation.
9. the method preparing cosmetic composition for hair described in claim 8, it is characterised in that described in specifically comprise the following steps that
(1) Chinese medicine extract, Coco-Glucoside are uniformly mixed at 65-75 DEG C 5-15min, at 65-75 DEG C, put 20-30min afterwards, form mixed liquor;
(2) mixed liquor in step (1) is heated to 75-85 DEG C, and adds melon glue Hydroxyproyl Trimethyl chlorination and deionized water is stirred, stir 10-12min;
(3), after being cooled to 45-50 DEG C, add preservative, i.e. obtain after stirring.
10. the shampoo of a hair growth, it is characterised in that described shampoo is prepared through method described in claim 9 by the raw material described in claim 8.
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CN106420461A (en) * | 2016-10-12 | 2017-02-22 | 广州丹奇日用化工厂有限公司 | Application of herbal extract composition in liquid shampoo with function of scalp nursing |
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CN104887573A (en) * | 2015-05-22 | 2015-09-09 | 刘学勤 | Rhodiola rosea traditional Chinese medicine healthcare shampoo |
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