CN103385843A - Speckle-removing composition, preparation method thereof and applications thereof - Google Patents
Speckle-removing composition, preparation method thereof and applications thereof Download PDFInfo
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- CN103385843A CN103385843A CN2013103089440A CN201310308944A CN103385843A CN 103385843 A CN103385843 A CN 103385843A CN 2013103089440 A CN2013103089440 A CN 2013103089440A CN 201310308944 A CN201310308944 A CN 201310308944A CN 103385843 A CN103385843 A CN 103385843A
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Abstract
The invention discloses a speckle-removing composition, a preparation method thereof and applications thereof. The speckle-removing composition is prepared from raw materials, by weight, comprising 5-20 parts of saussurea involucrate, 5-20 parts of donkey-hide glue, 5-25 parts of liquorice, 5-25 parts of placenta, 5-20 parts of collagen, 5-20 parts of hyaluronic acid, 5-25 parts of vitamin E, 1-15 parts of vitamin B6, 5-20 parts of oat polypeptides, 5-20 parts of pearl powder, 1-20 parts of aloe, 5-25 parts of safflower, 5-25 parts of white peony roots, 1-20 parts of vitamin C, 5-20 parts of vitamin B3 and 1-15 parts of vitamin B5. The invention provides the speckle-removing composition. The speckle-removing composition has advantages of no irritation; no toxic or side effects; high safety; no hypersensitivity; capability of providing radical cure; good speckle removing effects; low recurrence rate; capability of replenishing nutrition for skin, whitening skin, preserving moisture and repairing skin pits; and capability of making skin smooth, fine, white, clear and wettish. The speckle removing cure rate is 96.7%.
Description
Technical field
The invention belongs to the Chinese medicine cosmetics and skincare product field of speckle dispelling, particularly a kind of spot-eliminating composition with pure plant material preparation and preparation method thereof and purposes.
Technical background
" disorder of QI duke or princess under an emperor during the General Treatise on the Cause and Symptoms of Diseases " is upper to be said, and speckle refers to send out in the speckle of redness of skin surface or purplish red, light red, black, sepia, the connected greatly slabbing of point, and that lays one's hand on is not in the way.Speckle belongs to heat syndrome, excess syndrome more, and due to the difference that forms reason, speckle can be divided into again freckle, chloasma, sunburn, cyasma, hydrargyrum speckle, tinea versicolor, black speck, senile plaque etc.Some speckles are more and more serious with advancing age, even can develop into whole face to be all.Speckle not only has a strong impact on the attractive in appearance of people, and allows the people feel oneself inferior, and affects people's Confidence, is a kind of people's of having a strong impact on able-bodied dermatosis, but speckle dispelling ought can allow again speckle increase the weight of, and other side effect even occur.Therefore safe speckle dispelling is personage's the unremitting pursue of liking to be beautiful always.The speckle dispelling product that occurs on the market at present is varied, but seldom have, can reach radical cure and preventive effect.Chinese patent CN102614368A discloses a kind of spot-eliminating composition, said composition makes take Six-element Chinese herbal medicine such as Bulbus Lilii 10-100, Herba Saussureae Involueratae 10-100, Radix Angelicae Dahuricae 10-100, Aloe 10-100, Flos Caryophylli 10-100, Flos persicae 10-100 as raw material, therapeutic effect to speckle on skin is better, but the problem that does not relate to relapse rate, and to the reparation of the moisturizing of skin, skin pit and smoothly study.
Summary of the invention
The purpose of this invention is to provide a kind of freckle effect good, do not recur, also have simultaneously the spot-eliminating composition of whitening, moisturizing, reparation pit, level and smooth skin effect.
Another object of the present invention is to provide the Preparation method and use of this spot-eliminating composition.
Spot-eliminating composition of the present invention, the primary raw material weight portion of the described spot-eliminating composition of preparation consists of: Herba Saussureae Involueratae 5-20, Colla Corii Asini 5-20, Radix Glycyrrhizae 5-25, Placenta Hominis 5-25, collagen protein 5-20, hyaluronic acid 5-20, vitamin E 5-25, vitamin B6 1-15, oat polypeptide 5-20, Margarita powder 5-20.
Spot-eliminating composition of the present invention, the described spot-eliminating composition for preparing also comprises the raw material of following weight portion composition: Aloe 1-20, Flos Carthami 5-25, Radix Paeoniae Alba 5-25, vitamin C 1-20, vitamin B3 5-20, vitamin B5 1-15.
Spot-eliminating composition of the present invention, described Radix Glycyrrhizae is Radix Glycyrrhizae, described Placenta Hominis is Placenta caprae seu ovis, the primary raw material weight portion of described spot-eliminating composition consists of: Herba Saussureae Involueratae 12-15, Colla Corii Asini 13-16, Radix Glycyrrhizae 12-15, Placenta caprae seu ovis 13-18, collagen protein 16-18, hyaluronic acid 13-15, vitamin e1 5-20, vitamin B6 6-8, oat polypeptide 12-16, Margarita powder 13-18, Aloe 5-10, Flos Carthami 10-18, Radix Paeoniae Alba 12-20, vitamin C 8-16, vitamin B3 11-16, vitamin B5 5-10.
Spot-eliminating composition of the present invention, the primary raw material weight portion for preparing described spot-eliminating composition consists of: Herba Saussureae Involueratae 14, Colla Corii Asini 15, Radix Glycyrrhizae 14, Placenta caprae seu ovis 15, collagen protein 17, hyaluronic acid 14, vitamin E 7, vitamin B6 7, oat polypeptide 14, Margarita powder 15, Aloe 8, Flos Carthami 15, the Radix Paeoniae Alba 16, vitamin C 17, vitamin B3 14, vitamin B5 8.
Spot-eliminating composition of the present invention, make QUBAN SHUANG with described spot-eliminating composition, and described QUBAN SHUANG comprises spot-eliminating composition and the adjuvant that following weight portion forms:
Spot-eliminating composition of the present invention, make the speckle dispelling breast with described spot-eliminating composition, and described speckle dispelling breast comprises spot-eliminating composition and the adjuvant that following weight portion forms:
Spot-eliminating composition of the present invention, make freckle-removing mask with described spot-eliminating composition, and described freckle-removing mask comprises spot-eliminating composition and the adjuvant that following weight portion forms:
The preparation method of spot-eliminating composition of the present invention, comprise the steps:
A) at first that Herba Saussureae Involueratae, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta caprae seu ovis seven flavor Chinese medicines are clean, cutting and dry, ratio of component is weighed by weight, and is standby;
B) then with collagen protein, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder also by weight ratio of component weigh, standby;
C) will claim Herba Saussureae Involueratae, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta Hominis decoct with water, at first add 8～16 times, water and soaked 15～45 minutes, then be heated to 100 ℃ and decoct lixiviate 1.5～2.5h, extracting solution 200 order filter-cloth filterings obtain filtrate 1 and medicinal residues; The gained medicinal residues are added 8～12 times of water be heated to 100 ℃ and decoct lixiviate 1～2h, extracting solution obtains filtrate 2 with 200 order filter-cloth filterings; Merge filtrate twice, standingly be reduced to room temperature to temperature, again use 200 order filter-cloth filterings, obtain filtrate 3, add 0.6～1.2 kilogram of 95% ethanol to filtrate 3, sedimentation lixiviate 20～28h, ethanol is reclaimed in blood pressure lowering, and reclaiming extracting solution after ethanol, to be evaporated to relative density be 0.8～1.2, obtains extract;
D) will claim collagen protein, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder mix homogeneously obtain mixture, described mixture is merged and mixs homogeneously with described extract, make body of paste, described body of paste is concentrated, obtain spot-eliminating composition.
The preparation method of spot-eliminating composition of the present invention, comprise the steps:
A) at first that Herba Saussureae Involueratae, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta caprae seu ovis seven flavor Chinese medicines are clean, cutting and dry, weigh standby;
B), then with collagen protein, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide, Margarita powder, weigh standby;
C) Herba Saussureae Involueratae of described weight, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta Hominis are decocted with water, at first add 12 times, water and soaked 30 minutes, then be heated to 100 ℃ and decoct lixiviate 2h, extracting solution 200 order filter-cloth filterings obtain filtrate 1 and medicinal residues; The gained medicinal residues are added 10 times of water be heated to 100 ℃ and decoct lixiviate 1.5h, extracting solution obtains filtrate 2 with 200 order filter-cloth filterings; Merge filtrate twice, standingly be reduced to room temperature to temperature, again use 200 order filter-cloth filterings, filtrate 3, add 1 kilogram of 95% ethanol, sedimentation lixiviate 24h to filtrate 3, ethanol is reclaimed in blood pressure lowering, and reclaiming extracting solution after ethanol, to be evaporated to relative density be 1, obtains extract;
D) will claim collagen protein, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder mix homogeneously obtain mixture, described mixture is merged and mixs homogeneously with described extract, make body of paste, described body of paste is concentrated, obtain spot-eliminating composition.
The application of spot-eliminating composition of the present invention in the cosmetics and skincare product of preparation treatment freckle, chloasma, pigmentation spots, senile plaque.
Spot-eliminating composition of the present invention, the application in the cosmetics and skincare product of preparation treatment freckle, chloasma, pigmentation spots, senile plaque etc.
In the present invention, the source of primary raw material used is as follows:
Herba Saussureae Involueratae (Saussurea involucrata): Compositae phoenix hair Chrysanthemum Herba Saussureae Involueratae subgenus herbaceous plant.The Herba Saussureae Involueratae sweet in the mouth, warm in nature.Heat-clearing and toxic substances removing, wind-damp dispelling, detumescence, pain relieving.
Colla Corii Asini (Colla Corii Asini): boil the glue that forms after the skin unhairing of equine species donkey.The YIN nourishing of enriching blood, moisturize, hemostasis.Be used for blood deficiency and yellow complexion, dizzy cardiopalmus, dysphoria and insomnia, xeropulmonary cough.
Radix Glycyrrhizae (Glycyrrhizae Preparata): leguminous plant.Tool burnt odor gas, distinguish the flavor of sweet.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Be Radix Glycyrrhizae without the Radix Glycyrrhizae of concocting, the experiment proved that, the spot-eliminating composition better effects if of the present invention that is made by Radix Glycyrrhizae.
Placenta Hominis (placenta): the healthy puerpera's of Hominidae Placenta Hominis, warm in nature, sweet in the mouth, salty; Return lung, liver, kidney channel; Benefiting QI and nourishing blood, the kidney invigorating and essence nourishing.Placenta caprae seu ovis: the Placenta Hominis that is sheep.Warm in nature, sweet in the mouth.The QI invigorating tonify deficiency, under warming middle-JIAO is warm, transfer the kidney invigorating void, weakness and emaciation, nourishing blood to tranquillize the mind, rich flesh skin care, life lengthening.Experiment showed, that Placenta caprae seu ovis not only is easy to get, and can the skin care skin moistening, the spot-eliminating composition better effects if of the present invention that is made by Placenta caprae seu ovis.
Aloe (Aloe): Liliaceae Aloe herbaceos perennial.Bitter in the mouth, cold in nature.Under rushing down, liver heat removing, parasite killing.
Flos Carthami (Fructus Schisandrae Chinensis): Compositae dicotyledon.Warm in nature, acrid in the mouth.Promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.
The Radix Paeoniae Alba (White Paeony Root): Ranunculaceae Paeonia plant.Cool in nature, bitter in the mouth acid.Nourishing blood to suppress the hyperactive liver, slow middle pain relieving, yin fluid astringing is received antiperspirant.
Collagen protein (collagen): collagen fiber obtain after Partial digestion has better water miscible protein.Supplement skin-nourishing, the collagen that strengthens in skin is active, skin care, slow down aging, beauty treatment, wrinkle-chasing, hair care.
Hyaluronic acid (hyaluronic acid): acid mucopolysaccharide.Lubricated joint, regulate Vascular Permeability, regulates protein, promotes wound healing, and water conservation, improve the skin-nourishing metabolism.
Vitamin E (vitamin E): be a kind of fatsoluble vitamin, claim again tocopherol.Slow down aging, minimizing cicatrix and the deposition of pigment, the healing of accelerated in wounds.
Vitamin B6 (vitamin B6): be a kind of water soluble vitamins, a kind of vitamin B group that contains pyridoxol or 2-methyl-3-hydroxy-4-formyl-5-hydroxymethylpyridine. or pyridoxamine.
Oat polypeptide: a kind of polypeptide that is obtained through enzymolysis by avenin.Have excellent performance of keeping humidity, strengthen skin elasticity, accelerate cell proliferation and metabolism, Cucumber Extract, reduce skin coarseness, the opposing free radical.
Margarita powder (pearl powder): with the fine powder of Margarita grinding.The traditional Chinese medical science is used as the medicine of the arresting convulsion of calming the nerves, suppressing the hyperactive liver improving eyesight, convergence granulation promoting.
Vitamin C (vitamin C): be a kind of water soluble vitamins.Antioxidation, the metabolism of raising cell.
Vitamin B3 (vitamin B3): being again nicotinic acid, is a kind of water soluble vitamins.Healthy skin, improve blood circulation.
Vitamin B5 (pantothenic acid): be again pantothenic acid, be white powder.The help cell forms, and makes and upgrades bodily tissue, promotes wound healing, and external can increase the hydration of skin.
Beneficial effect of the present invention is:
(1) adopt raw material mostly to be degree of safety high pure plant or pure plant extracts, the spot-eliminating composition of preparation is non-stimulated, have no side effect, and degree of safety is high, allergic phenomena can not occur, can effect a radical cure, do not recur, speckle dispelling cure rate and effective percentage are higher, cure rate 96.7%, effective percentage 100%.
(2) spot-eliminating composition of the present invention, not only freckle effect is good, can also supplement skin nutrition, whitening, moisturizing, reparation skin pit, makes fine and smooth, the fair and clear water profit of skin smooth.
, for this situation is described, now by test example, further illustrate effect of the present invention as follows:
The Evaluation of Functional test
Test group 30 examples, 10～65 years old age, average 40 years old, long pinta journey 2～8 months.
Occupation mode: test group: external spot-eliminating composition of the present invention, every day, each used once sooner or later, used continuously two courses for the treatment of, and be one month a course for the treatment of.Matched group: flourish spot-removing ointment (composition: Margarita powder, Folium Kaki) is supported in external, and every day, each once, used two courses for the treatment of continuously sooner or later, and be two months a course for the treatment of.
Observation index: before and after observing treatment, which variation skin has.
(1) relatively treat the size of speckle on the skin of front and back
The speckle area at facial each position adds sum＜=5cm mutually
2For small size;
The speckle area sum 5～15cm at facial each position
2For middle area;
The speckle area at facial each position adds sum＞=15cm mutually
2For large tracts of land.
(2) relatively treat the shade of speckle on the skin of front and back
Pigment detection adopts the brown card Bn(C+M+Y in instrumental method or practical chromatograph card) (Institute of Geography, Academia Sinica's development, Mapping Press publishes).
(3) relatively have or not new speckle to occur on the skin for the treatment of front and back.
The number of original speckle position speckle increases but area reduces, and is considered as not producing new speckle.
Effect criterion:
Recovery from illness: speckle disappears, and does not have new speckle to occur.
Effectively: spot colors integration Jian Shao＞=18%, while speck area Jian Shao＞=10%, and do not have new speckle to occur.
Invalid: spot colors integration and area have no significant change or increase the weight of, and have new speckle to occur.
Result of the test is as follows:
Effect is judged: in the clinical trial of speckle dispelling, and test group external spot-eliminating composition of the present invention, cured person 29 examples, the responder is 30 examples, nonresponder's 0 example, cure rate 96.7%, effective percentage 100%; And matched group to take flourish heart ball healing person be that 15 examples, responder are 26 examples, nonresponder's 4 examples, cure rate 50%, effective percentage 86.7%.The effect for the treatment of group and matched group comparison shows that, spot-eliminating composition of the present invention, and speckle dispelling cure rate and effective percentage are higher, cure rate 96.7%, effective percentage 100%.The people who fully recovers in test group is paid a return visit, find in two years without the recidivist.
Typical case's application 1:
Lee, the female, 16 years old, face was without pit, and there is the light brown speckle wing of nose both sides, and the Exposure to Sunlight postemphasis is freckle after diagnosing, existing 4 years, used multiple speckle dispelling product, effect is all undesirable.Treatment: by using the QUBAN SHUANG that is made by spot-eliminating composition of the present invention the course for the treatment of, using method be early, evening respectively 1 time, first wash one's face with warm water before use, one month is 1 course for the treatment of.After treating 1 course for the treatment of, patient face spot colors integration reduces 28%, and speck area reduces 20% simultaneously, and without new speckle, occurs.Continue to use consolidated 1 course for the treatment of, speckle disappears, and without new speckle, occurs, the fair and clear water profit of skin.Follow-up investigation is found after 1 year without recurrence.
Typical case's application 2:
Zeng, the female, 50 years old, face had pox to print pit, and the yellowish-brown patch appears in two cheek symmetries, out-of-shape, clear border, the Exposure to Sunlight postemphasis, be diagnosed as chloasma, and existing 8 years, used multiple speckle dispelling product, effect is all undesirable.Treatment: by using the speckle dispelling breast that is made by spot-eliminating composition of the present invention the course for the treatment of, using method be early, evening respectively 1 time, first wash one's face with warm water before use, one month is 1 course for the treatment of.After treating 1 course for the treatment of, patient face speckle disappears substantially, face pit desalination, the fair and clear water profit of skin.Continue to use consolidated 1 course for the treatment of, speckle disappears, and without new speckle, occurs, face pit calms down, the fair and clear water profit of skin.Follow-up investigation is found after 1 year without recurrence.
Typical case's application 3:
Liu, female, 36 years old, the pitchy speckle appears in face, and is not of uniform size, and boundary is clearly demarcated, the Exposure to Sunlight postemphasis, be diagnosed as sunburn, existing 2 years, the multiple speckle dispelling product of readme, effect is all undesirable, goes to beauty parlor to do treatment then, and blotch removal has repeatedly by Exposure to Sunlight, and more serious, and allergic phenomena appears.Treatment: by using the freckle-removing mask that is made by spot-eliminating composition of the present invention the course for the treatment of, using method be early, evening respectively 1 time, first wash one's face with warm water before use, one month is 1 course for the treatment of.After treating 1 course for the treatment of, allergic symptom disappears, and face's speckle is desalinated to some extent; After continuing to use 2 courses for the treatment of, face's speckle disappears substantially, and skin water profit is glossy.Continue to use consolidated 1 course for the treatment of, speckle disappears, the fair and clear water profit of skin.Follow-up investigation is found after 1 year without recurrence.
Typical case's application 4:
Liu, female, 28 years old, readme before 2 years face the pitchy speckle appears, rear use skin-lightening cosmetic, speckle is thin out before this, skin truly has and bleaches, and after using 5 months, skin speckle increases, and spot colors does not increase the weight of, the hydrargyrum speckle that forms for the mercury element precipitation that causes because of the mercurous skin-lightening cosmetic of improper use after diagnosing, the multiple speckle dispelling product of readme, effect is all undesirable, not only repeatedly, and more serious, and allergic phenomena appears.Treatment: by using the QUBAN SHUANG that is made by spot-eliminating composition of the present invention the course for the treatment of, using method be early, evening respectively 1 time, first wash one's face with warm water before use, one month is 1 course for the treatment of.After treating 1 course for the treatment of, allergic symptom disappears, and face's speckle is desalinated to some extent; After continuing to use 2 courses for the treatment of, face's speckle major part is thin out, and face's colour of skin integral body bleaches to some extent and highlights; After continuing to use 2 courses for the treatment of, face's speckle disappears substantially, and face's colour of skin integral body bleaches to some extent and highlights, and skin water profit is glossy; Continue to use consolidated 1 course for the treatment of, speckle disappears, the fair and clear water profit of skin.Follow-up investigation is found after 1 year without recurrence.
Typical case's application 5:
Zhang, the female, 60 years old, brown plaque all appearred in readme 5 years front faces, forehead, back, cervical region, front and arms, was " senile pigmented spots " after diagnosing, the multiple speckle dispelling product of readme, effect is all undesirable.Treatment: by using the speckle dispelling breast that is made by spot-eliminating composition of the present invention the course for the treatment of, using method be early, evening respectively 1 time, first use warm water cleaning speckle place before use, one month is 1 course for the treatment of.After treating 2 courses for the treatment of, speckle is slightly desalinated; After continuing to use 2 courses for the treatment of, the speckle desalination, it is smooth that skin shows slightly; After continuing to use 2 courses for the treatment of, face's speckle disappears substantially, and colour of skin integral body bleaches to some extent and highlights, and skin is smooth; Continue to use consolidated 1 course for the treatment of, speckle disappears, and skin integral body bleaches, skin smooth.Follow-up investigation is found after 1 year without recurrence.
The specific embodiment
The invention will be further described below in conjunction with embodiment:
Embodiment 1 QUBAN SHUANG
Prescription:
Herba Saussureae Involueratae 20g, Colla Corii Asini 20g, Radix Glycyrrhizae 25g, Placenta Hominis 25g, collagen protein 20g, hyaluronic acid 20g, vitamin E2 5g, vitamin B6 15g, oat polypeptide 20g, Margarita powder 20g, Aloe 20g, Flos Carthami 25g, Radix Paeoniae Alba 25g, Catergen 0g, vitamin B3 20g, vitamin B5 15g; Deionized water 5332g, lanoline 799.8g, sorbitol 5.332g, methoxybenzene 5.332 * 10
-3g。
Method for making:
A) at first that Herba Saussureae Involueratae, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta Hominis seven flavor Chinese medicines are clean, cutting and dry, weigh by weight, and is standby;
B) then collagen protein, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder are also weighed by weight, standby;
C) Herba Saussureae Involueratae of described weight, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta Hominis are decocted with water, at first add 8 times, water and soaked 15 minutes, then be heated to 100 ℃ and decoct lixiviate 1.5h, extracting solution 200 order filter-cloth filterings obtain filtrate 1 and medicinal residues; The gained medicinal residues are added 80 times of water be heated to 100 ℃ and decoct lixiviate 10h, extracting solution obtains filtrate 2 with 200 order filter-cloth filterings; Merge filtrate twice, standingly be reduced to room temperature to temperature, again use 200 order filter-cloth filterings, filtrate 3, add 0.60 kilogram of 95% ethanol, sedimentation lixiviate 200h to filtrate 3, ethanol is reclaimed in blood pressure lowering, and reclaiming extracting solution after ethanol, to be evaporated to relative density be 0.8, obtains the 16g extract;
D) collagen protein of described weight, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder mix homogeneously are obtained mixture, described mixture is merged and mixs homogeneously with described extract, make body of paste, described body of paste is concentrated, obtain 2666g spot-eliminating composition of the present invention.
E) to the deionized water, lanoline, sorbitol and the methoxybenzene that add described weight in described 2666g spot-eliminating composition, and conventional post processing, make QUBAN SHUANG.
Embodiment 2 speckle dispelling breasts
Prescription:
Herba Saussureae Involueratae 10g, Colla Corii Asini 10g, Radix Glycyrrhizae 16g, Placenta Hominis 10g, collagen protein 10g, hyaluronic acid 10g, vitamin e1 0g, vitamin B6 5g, oat polypeptide 10g, Margarita powder 10g, Aloe 3g, Flos Carthami 8g, Radix Paeoniae Alba 8g, vitamin C 5g, vitamin B3 9g, vitamin B5 3g; Deionized water 314g, lanoline 15.7g, lecithin 2.355 * 10
-5G, propylene glycol 0.157g and sorbic acid 0.157g.
Method for making:
A) at first that Herba Saussureae Involueratae, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta Hominis seven flavor Chinese medicines are clean, cutting and dry, weigh by weight, and is standby;
B) then collagen protein, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder are also weighed by weight, standby;
C) Herba Saussureae Involueratae of described weight, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta Hominis are decocted with water, at first add 16 times, water and soaked 45 minutes, then be heated to 100 ℃ and decoct lixiviate 2.5h, extracting solution 200 order filter-cloth filterings obtain filtrate 1 and medicinal residues; The gained medicinal residues are added 12 times of water be heated to 100 ℃ and decoct lixiviate 2h, extracting solution obtains filtrate 2 with 200 order filter-cloth filterings; Merge filtrate twice, standingly be reduced to room temperature to temperature, again use 200 order filter-cloth filterings, filtrate 3, add 1.2 kilograms of 95% ethanol, sedimentation lixiviate 28h to filtrate 3, ethanol is reclaimed in blood pressure lowering, and reclaiming extracting solution after ethanol, to be evaporated to relative density be 1.2, obtains the 6.5g extract;
D) collagen protein of described weight, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder mix homogeneously are obtained mixture, described mixture is merged and mixs homogeneously with described extract, make body of paste, described body of paste is concentrated, obtain 78.5g spot-eliminating composition of the present invention.
E) to the deionized water, lanoline, lecithin, propylene glycol and the sorbic acid that add described weight in described 78.5g spot-eliminating composition, and conventional post processing, make the speckle dispelling breast.
Embodiment 3 freckle-removing masks
Prescription:
Herba Saussureae Involueratae 14g, Colla Corii Asini 15g, Radix Glycyrrhizae 14g, Placenta Hominis 15g, collagen protein 17g, hyaluronic acid 14g, vitamin E 7g, vitamin B6 7g, oat polypeptide 14g, Margarita powder 15g, Aloe 8g, Flos Carthami 15g, Radix Paeoniae Alba 16g, vitamin C 17g, vitamin B3 14g, vitamin B5 8g; Deionized water 368.1g, lanoline 36.81g, glycerol 2.454 * 10
-2G, citric acid 3.681 * 10
-5G, propylene glycol 3.681 * 10
-3g。
Method for making:
A) at first that Herba Saussureae Involueratae, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta Hominis seven flavor Chinese medicines are clean, cutting and dry, weigh by weight, and is standby;
B) then collagen protein, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder are also weighed by weight, standby;
C) Herba Saussureae Involueratae of described weight, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta Hominis are decocted with water, at first add 12 times, water and soaked 30 minutes, then be heated to 100 ℃ and decoct lixiviate 2h, extracting solution 200 order filter-cloth filterings obtain filtrate 1 and medicinal residues; The gained medicinal residues are added 10 times of water be heated to 100 ℃ and decoct lixiviate 1.5h, extracting solution obtains filtrate 2 with 200 order filter-cloth filterings; Merge filtrate twice, standingly be reduced to room temperature to temperature, again use 200 order filter-cloth filterings, filtrate 3, add 1 kilogram of 95% ethanol, sedimentation lixiviate 24h to filtrate 3, ethanol is reclaimed in blood pressure lowering, and reclaiming extracting solution after ethanol, to be evaporated to relative density be 1.0, obtains the 9.7g extract;
D) collagen protein of described weight, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder mix homogeneously are obtained mixture, described mixture is merged and mixs homogeneously with described extract, make body of paste, described body of paste is concentrated, obtain 122.7g spot-eliminating composition of the present invention.
E) to the deionized water, lanoline, glycerol, citric acid and the propylene glycol that add described weight in described 122.7g spot-eliminating composition, and conventional post processing, make freckle-removing mask.
Embodiment 4 QUBAN SHUANG
Prescription:
Herba Saussureae Involueratae 20g, Colla Corii Asini 20g, Radix Glycyrrhizae 25g, Placenta Hominis 25g, collagen protein 20g, hyaluronic acid 20g, vitamin E2 5g, vitamin B6 15g, oat polypeptide 20g, Margarita powder 20g; Deionized water 129g, lanoline 38.7g, sorbitol 2.58 * 10
-2G, methoxybenzene 1.935 * 10
-5g。
Method for making:
A) at first that Herba Saussureae Involueratae, Colla Corii Asini, Radix Glycyrrhizae and Aloe four flavor Chinese medicines are clean, cutting and dry, weigh by weight, and is standby;
B) then collagen protein, hyaluronic acid, vitamin E, vitamin B6, oat polypeptide and Margarita powder are also weighed by weight, standby;
C) Herba Saussureae Involueratae of described weight, Colla Corii Asini, Radix Glycyrrhizae and Aloe are decocted with water, at first add 8 times, water and soaked 15 minutes, then be heated to 100 ℃ and decoct lixiviate 1.5h, extracting solution 200 order filter-cloth filterings obtain filtrate 1 and medicinal residues; The gained medicinal residues are added 80 times of water be heated to 100 ℃ and decoct lixiviate 10h, extracting solution obtains filtrate 2 with 200 order filter-cloth filterings; Merge filtrate twice, standingly be reduced to room temperature to temperature, again use 200 order filter-cloth filterings, filtrate 3, add 0.60 kilogram of 95% ethanol, sedimentation lixiviate 200h to filtrate 3, ethanol is reclaimed in blood pressure lowering, and reclaiming extracting solution after ethanol, to be evaporated to relative density be 0.8, obtains the 9g extract;
D) collagen protein of described weight, hyaluronic acid, vitamin E, vitamin B6, oat polypeptide and Margarita powder mix homogeneously are obtained mixture, described mixture is merged and mixs homogeneously with described extract, make body of paste, described body of paste is concentrated, obtain 129g spot-eliminating composition of the present invention.
E) to the deionized water, lanoline, sorbitol and the methoxybenzene that add described weight in described 129g spot-eliminating composition, and conventional post processing, make QUBAN SHUANG.
Embodiment 5 speckle dispelling breasts
Prescription:
Herba Saussureae Involueratae 5g, Colla Corii Asini 5g, Radix Glycyrrhizae 5g, Placenta Hominis 10g, collagen protein 5g, hyaluronic acid 5g, vitamin E 5g, vitamin B6 1g, oat polypeptide 5g, Margarita powder 5g, Aloe 1g, Flos Carthami 5g, Radix Paeoniae Alba 5g, vitamin C 1g, vitamin B3 5g, vitamin B5 1g; Deionized water 54.9g, lanoline 7.32g, lecithin 5.49 * 10
-6G, propylene glycol 4.575 * 10
-2G and sorbic acid 3.66 * 10
-2g。
Method for making:
A) at first that Herba Saussureae Involueratae, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta Hominis seven flavor Chinese medicines are clean, cutting and dry, weigh by weight, and is standby;
B) then collagen protein, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder are also weighed by weight, standby;
C) Herba Saussureae Involueratae of described weight, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta Hominis are decocted with water, at first add 9 times, water and soaked 40 minutes, then be heated to 100 ℃ and decoct lixiviate 2.2h, extracting solution 200 order filter-cloth filterings obtain filtrate 1 and medicinal residues; The gained medicinal residues are added 9 times of water be heated to 100 ℃ and decoct lixiviate 2h, extracting solution obtains filtrate 2 with 200 order filter-cloth filterings; Merge filtrate twice, standingly be reduced to room temperature to temperature, again use 200 order filter-cloth filterings, filtrate 3, add 0.8 kilogram of 95% ethanol, sedimentation lixiviate 26h to filtrate 3, ethanol is reclaimed in blood pressure lowering, and reclaiming extracting solution after ethanol, to be evaporated to relative density be 1.2, obtains the 3.6g extract;
D) collagen protein of described weight, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder mix homogeneously are obtained mixture, described mixture is merged and mixs homogeneously with described extract, make body of paste, described body of paste is concentrated, obtain 36.6g spot-eliminating composition of the present invention.
E) to the deionized water, lanoline, lecithin, propylene glycol and the sorbic acid that add described weight in described 36.6g spot-eliminating composition, and conventional post processing, make the speckle dispelling breast.
Embodiment 6 QUBAN SHUANG
Prescription:
Herba Saussureae Involueratae 18g, Colla Corii Asini 19g, Radix Glycyrrhizae 16g, Placenta Hominis 20g, collagen protein 19g, hyaluronic acid 18g, vitamin E2 2g, vitamin B6 10g, oat polypeptide 18g, Margarita powder 20g, Aloe 15g, Flos Carthami 20g, Radix Paeoniae Alba 22g, vitamin C 18g, vitamin B3 17g, vitamin B5 12g; Deionized water 167g, lanoline 41.75g, sorbitol 2.505 * 10
-2G, methoxybenzene 1.67 * 10
-5g。
Method for making:
A) at first that Herba Saussureae Involueratae, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta Hominis seven flavor Chinese medicines are clean, cutting and dry, weigh by weight, and is standby;
B) then collagen protein, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder are also weighed by weight, standby;
C) Herba Saussureae Involueratae of described weight, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta Hominis are decocted with water, at first add 8 times, water and soaked 15 minutes, then be heated to 100 ℃ and decoct lixiviate 1.5h, extracting solution 200 order filter-cloth filterings obtain filtrate 1 and medicinal residues; The gained medicinal residues are added 80 times of water be heated to 100 ℃ and decoct lixiviate 10h, extracting solution obtains filtrate 2 with 200 order filter-cloth filterings; Merge filtrate twice, standingly be reduced to room temperature to temperature, again use 200 order filter-cloth filterings, filtrate 3, add 0.60 kilogram of 95% ethanol, sedimentation lixiviate 200h to filtrate 3, ethanol is reclaimed in blood pressure lowering, and reclaiming extracting solution after ethanol, to be evaporated to relative density be 0.8, obtains the 13g extract;
D) collagen protein of described weight, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder mix homogeneously are obtained mixture, described mixture is merged and mixs homogeneously with described extract, make body of paste, described body of paste is concentrated, obtain 167g spot-eliminating composition of the present invention.
E) to the deionized water, lanoline, sorbitol, the methoxybenzene that add described weight in described 167g spot-eliminating composition, and conventional post processing, make QUBAN SHUANG.
Embodiment 7 freckle-removing masks
Prescription:
Herba Saussureae Involueratae 12g, Colla Corii Asini 13g, Radix Glycyrrhizae 12g, Placenta caprae seu ovis 13g, collagen protein 16g, hyaluronic acid 13g, vitamin e1 5g, vitamin B6 6g, oat polypeptide 12g, Margarita powder 13g, Aloe 5g, Flos Carthami 10g, Radix Paeoniae Alba 12g, vitamin C 8g, vitamin B3 11g, vitamin B5 5g; Deionized water 133.375g, lanoline 26.675g, glycerol 1.067 * 10
-2G, citric acid 1.867 * 10
-5G, propylene glycol 1.334 * 10
-3g。。
Method for making:
A) at first that Herba Saussureae Involueratae, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta Hominis seven flavor Chinese medicines are clean, cutting and dry, weigh by weight, and is standby;
B) then collagen protein, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder are also weighed by weight, standby;
C) Herba Saussureae Involueratae of described weight, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta Hominis are decocted with water, at first add 12 times, water and soaked 30 minutes, then be heated to 100 ℃ and decoct lixiviate 2h, extracting solution 200 order filter-cloth filterings obtain filtrate 1 and medicinal residues; The gained medicinal residues are added 10 times of water be heated to 100 ℃ and decoct lixiviate 1.5h, extracting solution obtains filtrate 2 with 200 order filter-cloth filterings; Merge filtrate twice, standingly be reduced to room temperature to temperature, again use 200 order filter-cloth filterings, filtrate 3, add 1 kilogram of 95% ethanol, sedimentation lixiviate 24h to filtrate 3, ethanol is reclaimed in blood pressure lowering, and reclaiming extracting solution after ethanol, to be evaporated to relative density be 1.0, obtains the 7.7g extract;
D) collagen protein of described weight, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder mix homogeneously are obtained mixture, described mixture is merged and mixs homogeneously with described extract, make body of paste, described body of paste is concentrated, obtain 106.7g spot-eliminating composition of the present invention.
E) to the deionized water, lanoline, glycerol, citric acid and the propylene glycol that add described weight in described 106.7g spot-eliminating composition, and conventional post processing, make the speckle dispelling breast.
Embodiment 8 QUBAN SHUANG
Prescription:
Herba Saussureae Involueratae 15g, Colla Corii Asini 16g, Radix Glycyrrhizae 15g, Placenta caprae seu ovis 18g, collagen protein 18g, hyaluronic acid 15g, vitamin E2 0g, vitamin B6 8g, oat polypeptide 16g, Margarita powder 18g, Aloe 10g, Flos Carthami 18g, Radix Paeoniae Alba 20g, vitamin C 16g, vitamin B3 16g, vitamin B5 10g; Deionized water 222.3g, lanoline 44.46g, sorbitol 2.964 * 10
-2G, methoxybenzene 2.223 * 10
-5g。
Method for making:
A) at first that Herba Saussureae Involueratae, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta caprae seu ovis seven flavor Chinese medicines are clean, cutting and dry, weigh by weight, and is standby;
B) then collagen protein, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder are also weighed by weight, standby;
C) Herba Saussureae Involueratae of described weight, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Foetus Caprae seu Ovis are decocted with water, at first add 8 times, water and soaked 15 minutes, then be heated to 100 ℃ and decoct lixiviate 1.5h, extracting solution 200 order filter-cloth filterings obtain filtrate 1 and medicinal residues; The gained medicinal residues are added 80 times of water be heated to 100 ℃ and decoct lixiviate 10h, extracting solution obtains filtrate 2 with 200 order filter-cloth filterings; Merge filtrate twice, standingly be reduced to room temperature to temperature, again use 200 order filter-cloth filterings, filtrate 3, add 0.60 kilogram of 95% ethanol, sedimentation lixiviate 200h to filtrate 3, ethanol is reclaimed in blood pressure lowering, and reclaiming extracting solution after ethanol, to be evaporated to relative density be 0.8, obtains the 11.2g extract;
D) collagen protein of described weight, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder mix homogeneously are obtained mixture, described mixture is merged and mixs homogeneously with described extract, make body of paste, described body of paste is concentrated, obtain 148.2g spot-eliminating composition of the present invention.
E) to the deionized water, lanoline, sorbitol and the methoxybenzene that add described weight in described 148.2g spot-eliminating composition, and conventional post processing, make QUBAN SHUANG.
Claims (10)
1. spot-eliminating composition, it is characterized in that, the primary raw material weight portion of the described spot-eliminating composition of preparation consists of: Herba Saussureae Involueratae 5-20, Colla Corii Asini 5-20, Radix Glycyrrhizae 5-25, Placenta Hominis 5-25, collagen protein 5-20, hyaluronic acid 5-20, vitamin E 5-25, vitamin B6 1-15, oat polypeptide 5-20, Margarita powder 5-20.
2. spot-eliminating composition according to claim 1, it is characterized in that, the described spot-eliminating composition for preparing also comprises the raw material of following weight portion composition: Aloe 1-20, Flos Carthami 5-25, Radix Paeoniae Alba 5-25, vitamin C 1-20, vitamin B3 5-20, vitamin B5 1-15.
3. spot-eliminating composition according to claim 2, it is characterized in that, described Radix Glycyrrhizae is Radix Glycyrrhizae, described Placenta Hominis is Placenta caprae seu ovis, the primary raw material weight portion of described spot-eliminating composition consists of: Herba Saussureae Involueratae 12-15, Colla Corii Asini 13-16, Radix Glycyrrhizae 12-15, Placenta caprae seu ovis 13-18, collagen protein 16-18, hyaluronic acid 13-15, vitamin e1 5-20, vitamin B6 6-8, oat polypeptide 12-16, Margarita powder 13-18, Aloe 5-10, Flos Carthami 10-18, Radix Paeoniae Alba 12-20, vitamin C 8-16, vitamin B3 11-16, vitamin B5 5-10.
4. spot-eliminating composition according to claim 3, it is characterized in that, the primary raw material weight portion for preparing described spot-eliminating composition consists of: Herba Saussureae Involueratae 14, Colla Corii Asini 15, Radix Glycyrrhizae 14, Placenta caprae seu ovis 15, collagen protein 17, hyaluronic acid 14, vitamin E 7, vitamin B6 7, oat polypeptide 14, Margarita powder 15, Aloe 8, Flos Carthami 15, the Radix Paeoniae Alba 16, vitamin C 17, vitamin B3 14, vitamin B5 8.
5. according to claim 1～4 described any one spot-eliminating compositions, is characterized in that, described spot-eliminating composition is made QUBAN SHUANG, and described QUBAN SHUANG comprises spot-eliminating composition and the adjuvant that following weight portion forms:
6. according to claim 1～4 described any one spot-eliminating compositions, is characterized in that, described spot-eliminating composition is made the speckle dispelling breast, and described speckle dispelling breast comprises spot-eliminating composition and the adjuvant that following weight portion forms:
7. according to claim 1～4 described any one spot-eliminating compositions, is characterized in that, described spot-eliminating composition is made freckle-removing mask, and described freckle-removing mask comprises spot-eliminating composition and the adjuvant that following weight portion forms:
8. the preparation method of according to claim 2～4 described any one spot-eliminating compositions, is characterized in that, described method comprises the steps:
A) at first that Herba Saussureae Involueratae, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta caprae seu ovis seven flavor Chinese medicines are clean, cutting and dry, ratio of component is weighed by weight, and is standby;
B) then with collagen protein, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder also by weight ratio of component weigh, standby;
C) will claim Herba Saussureae Involueratae, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta Hominis decoct with water, at first add 8～16 times, water and soaked 15～45 minutes, then be heated to 100 ℃ and decoct lixiviate 1.5～2.5h, extracting solution 200 order filter-cloth filterings obtain filtrate 1 and medicinal residues; The gained medicinal residues are added 8～12 times of water be heated to 100 ℃ and decoct lixiviate 1～2h, extracting solution obtains filtrate 2 with 200 order filter-cloth filterings; Merge filtrate twice, standingly be reduced to room temperature to temperature, again use 200 order filter-cloth filterings, obtain filtrate 3, add 0.6～1.2 kilogram of 95% ethanol to filtrate 3, sedimentation lixiviate 20～28h, ethanol is reclaimed in blood pressure lowering, and reclaiming extracting solution after ethanol, to be evaporated to relative density be 0.8～1.2, obtains extract;
D) will claim collagen protein, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder mix homogeneously obtain mixture, described mixture is merged and mixs homogeneously with described extract, make body of paste, described body of paste is concentrated, obtain spot-eliminating composition.
9. the preparation method of spot-eliminating composition according to claim 4, is characterized in that, described method comprises the steps:
A) at first that Herba Saussureae Involueratae, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta caprae seu ovis seven flavor Chinese medicines are clean, cutting and dry, weigh standby;
B), then with collagen protein, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide, Margarita powder, weigh standby;
C) Herba Saussureae Involueratae of described weight, Colla Corii Asini, Radix Glycyrrhizae, Aloe, Flos Carthami, the Radix Paeoniae Alba and Placenta Hominis are decocted with water, at first add 12 times, water and soaked 30 minutes, then be heated to 100 ℃ and decoct lixiviate 2h, extracting solution 200 order filter-cloth filterings obtain filtrate 1 and medicinal residues; The gained medicinal residues are added 10 times of water be heated to 100 ℃ and decoct lixiviate 1.5h, extracting solution obtains filtrate 2 with 200 order filter-cloth filterings; Merge filtrate twice, standingly be reduced to room temperature to temperature, again use 200 order filter-cloth filterings, filtrate 3, add 1 kilogram of 95% ethanol, sedimentation lixiviate 24h to filtrate 3, ethanol is reclaimed in blood pressure lowering, and reclaiming extracting solution after ethanol, to be evaporated to relative density be 1, obtains extract;
D) will claim collagen protein, hyaluronic acid, vitamin C, vitamin E, vitamin B6, vitamin B3, vitamin B5, oat polypeptide and Margarita powder mix homogeneously obtain mixture, described mixture is merged and mixs homogeneously with described extract, make body of paste, described body of paste is concentrated, obtain spot-eliminating composition.
10. the application of according to claim 1～4 described any one spot-eliminating compositions in the cosmetics and skincare product of preparation treatment freckle, chloasma, pigmentation spots, senile plaque.
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