CN109602687A - A kind of whitening spot-eliminating composition - Google Patents

A kind of whitening spot-eliminating composition Download PDF

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Publication number
CN109602687A
CN109602687A CN201910125049.2A CN201910125049A CN109602687A CN 109602687 A CN109602687 A CN 109602687A CN 201910125049 A CN201910125049 A CN 201910125049A CN 109602687 A CN109602687 A CN 109602687A
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CN
China
Prior art keywords
whitening spot
whitening
eliminating composition
spot
goat placenta
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Pending
Application number
CN201910125049.2A
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Chinese (zh)
Inventor
王清秀
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Guangdong Peptide Shijia Biotechnology Co Ltd
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Individual
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Priority to CN201910125049.2A priority Critical patent/CN109602687A/en
Publication of CN109602687A publication Critical patent/CN109602687A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/981Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of mammals or bird
    • A61K8/982Reproductive organs; Embryos, Eggs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/23Sulfur; Selenium; Tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/02Preparations for care of the skin for chemically bleaching or whitening the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a kind of whitening spot-eliminating compositions, including following substance: glycerol, propylene glycol, Natrulon H-10, NaCl, methoxysalicylic acid potassium, Trenaxmine, buffer, sodium hydrogensulfite, 1,2 hexylene glycols, VC ethylether, preservative, KF-6017, EM90, DC345, dimethyl silicone polymer, carbonic acid dioctyl ester, the poly- certain herbaceous plants with big flowers alkene of hydrogenation, atoleine, essence, Goat Placenta hydrolysate, nonapeptide -1, dipeptides -2, tetrapeptide -27, iron oxide red;The composition inhibits pigmentation, whitening spot-removing, bright color from source;For whitening, light spot, bright color and the uniformity, in addition can also prevent to return after laser operation black.

Description

A kind of whitening spot-eliminating composition
Technical field
The present invention relates to cosmetic technical fields, more particularly, to a kind of whitening spot-eliminating composition and its application.
Background technique
It is read because the tradition of " a white screening three is ugly " is beautiful, Asia women has whitening persistent pursuit, and all kinds of whitenings produce Product emerge one after another with method, and melanin is a kind of protein for being present in everyone skin base layer, and ultraviolet irradiation can enable Melanin generates variation, generates a kind of substance for protecting skin, then melanin and moving layer by layer via cell metabolism, arrive Skin epidermis forms color spot and the irregular equal skin problems of the colour of skin that we are seen.
Whitening and freckle-removing product is varied on the market, and the active constituent for playing effect can be roughly divided into four classes: (1) Sepiwhite, nine victory peptides etc. mainly reduce stimulation skin;(2) resorcinol class, arbutin, chromabright, kojic acid, Tannic acid etc., mainly inhibition melanin generate;(3) niacinamide, radix sophorae, green-tea extract, the mainly transmission of reduction melanin; (4) VC, tartaric acid salicylic acid, A analog derivative etc., mainly reduction, anti-oxidant or acceleration melanin metabolism etc.;The prior art is deposited Whitening product contain more chemically synthesized active constituent more, the feature of environmental protection is poor, and be easy to cause the side effect to human body.
Summary of the invention
According to an aspect of the present invention, present invention firstly provides be a kind of whitening spot-eliminating composition.
A kind of whitening spot-eliminating composition, including following substance: glycerol, propylene glycol, Natrulon H-10, NaCl, methoxyl group water Poplar acid potassium, Trenaxmine, buffer, sodium hydrogensulfite, 1,2 hexylene glycols, VC ethylether, preservative, KF-6017, EM90, DC345, Dimethyl silicone polymer, carbonic acid dioctyl ester, the poly- certain herbaceous plants with big flowers alkene of hydrogenation, atoleine, essence, Goat Placenta hydrolysate, nonapeptide -1, dipeptides - 2, tetrapeptide -27, iron oxide red.
In the above-mentioned whitening spot-eliminating composition of the present invention, nonapeptide -1 and dipeptides -2 form complex peptides, it is preferred that emphasis is inhibit, it is simultaneous Anti- saccharification is cared for, dark yellow skin is improved, removes free radical, Kohakuhi inhibits pigmentation from source, and whitening spot-removing highlights skin Color;Goat Placenta hydrolysate focuses on new life, provides various Porcine HGFs, such as epithelial cell growth factor (EGF), endothelium Porcine HGF (ECGF), fibroblast growth factor (FGF) etc. form a kind of new whitening mechanism, press down from source Melanin processed generates, and is used for whitening, light spot, bright color and the uniformity, in addition can also prevent to return after laser operation black.
In some specific embodiments, above-mentioned whitening spot-eliminating composition includes each substance of following mass percent: 5% glycerol, 25% propylene glycol, 5% Natrulon H-10,1%NaCl, 2% methoxysalicylic acid potassium, 2% Trenaxmine, 2% buffering Agent, 0.05% sodium hydrogensulfite, 0.4%1,2 hexylene glycols, 0.5%VC ethylether, 0.3% preservative, 2.8%KF-6017, 0.5%EM90,5%DC345,5% dimethyl silicone polymer, 2% carbonic acid dioctyl ester, the 1% poly- certain herbaceous plants with big flowers alkene of hydrogenation, 2% atoleine, 0.2% essence, 0.03% Goat Placenta hydrolysate, 0.3% nonapeptide -1,1% dipeptides -2,0.3% tetrapeptide -27,0.0014% iron oxide red, Surplus is deionized water.
In some specific embodiments, above-mentioned Goat Placenta hydrolysate is Goat Placenta Gly-His-Lys;Goat Placenta-peptide comes from pure day So, the placenta for the sheep that the feeding pregnancy period is 3-4 months is herded on free of contamination Siklingelei prairie;Goat Placenta is named sheep the 3-4 month Embryo is rich in thousands of kinds of nutritional ingredients, and Goat Placenta-peptide is exactly the complete sheep embryo for utilizing the stage, extracts by biological enzyme hydrolysis Natural biological preparation, have extremely strong bioactivity, cell metabolism can be enhanced, adjust human physiological functions comprehensively, play beauty Hold anti-aging function.
The effect with the following functions of Goat Placenta Gly-His-Lys:
1, the effective components such as the immunoglobulin in Goat Placenta-peptide, Porcine HGF, a variety of enzymes have anti-cell lipid mistake Oxidation, the effect for promoting skin metabolism, promoting cell division, anti-inflammatory, antiallergy and moisturizing.
2, remove spot, wrinkle effect: ultraviolet irradiation can produce active oxygen, and active oxygen generation will excessively overflow cell Become harmful substance outside, skin is made to generate melanin, Goat Placenta-peptide has the function of removing extracellular activity oxygen, so available In nti-freckle, anti-wrinkle.
3, anti-aging effects: active oxygen and the lipid peroxide by unsaturated fatty acid generation can make skin aging, sheep placenta Disk peptide has efficient removal to act on to this.
4, activate whitening efficacy: Goat Placenta-peptide contains the ingredients such as various amino acid, minerals and vitamin, especially containing with The related various growth factors of skin, such as epithelial cell growth factor (EGF), endothelial growth factor (ECGF), at fiber Porcine HGF (FGF) etc., therefore Goat Placenta-peptide has activation whitening efficacy to skin.
5, promote female hormone secretion, promote blood circulation, to postpone climacteric, delay senescence.
According to another aspect of the present invention, the application of above-mentioned whitening spot-eliminating composition is also provided, i.e., as whitening The product of nti-freckle is used for skin whitening, the spot of desalination removal skin;Alternatively, providing above-mentioned whitening spot-eliminating composition anti-ageing Application in old.
Specific embodiment
Below with reference to embodiment, the present invention is described in further detail.
Embodiment 1
Whitening spot-eliminating composition, each substance including following mass percent: 5% glycerol, 25% propylene glycol, 5% gather it is sweet Oily -10,1%NaCl, 2% methoxysalicylic acid potassium, 2% Trenaxmine, 2% buffer, 0.05% sodium hydrogensulfite, 0.4%1,2 Hexylene glycol, 0.5%VC ethylether, 0.3% preservative, 2.8%KF-6017,0.5%EM90,5%DC345,5% poly dimethyl Siloxanes, 2% carbonic acid dioctyl ester, the 1% poly- certain herbaceous plants with big flowers alkene of hydrogenation, 2% atoleine, 0.2% essence, 0.03% Goat Placenta hydrolysate, 0.3% nonapeptide -1,1% dipeptides -2,0.3% tetrapeptide -27,0.0014% iron oxide red, surplus are deionized water.
The whitening spot-eliminating composition for selecting 8 35-45 years old female subjects to be prepared using embodiment 1 uses 1 Month, it is sooner or later primary, be applied directly to face, neck and the back of the hand, to before and after use the case where given a mark (10 points are full marks, 6 points It is that skin is substantially qualified), as a result such as table 1.
Table 1
Above-described is only some embodiments of the present invention.For those of ordinary skill in the art, not Under the premise of being detached from the invention design, various modifications and improvements can be made, these belong to protection model of the invention It encloses.

Claims (5)

1. a kind of whitening spot-eliminating composition, which is characterized in that including following substance: glycerol, propylene glycol, Natrulon H-10, NaCl, methoxysalicylic acid potassium, Trenaxmine, buffer, sodium hydrogensulfite, 1,2 hexylene glycols, VC ethylether, preservative, KF- 6017, EM90, DC345, dimethyl silicone polymer, carbonic acid dioctyl ester, the poly- certain herbaceous plants with big flowers alkene of hydrogenation, atoleine, essence, Goat Placenta hydrolysis Object, nonapeptide -1, dipeptides -2, tetrapeptide -27, iron oxide red.
2. whitening spot-eliminating composition according to claim 1, which is characterized in that each object including following mass percent Matter: 5% glycerol, 25% propylene glycol, 5% Natrulon H-10,1%NaCl, 2% methoxysalicylic acid potassium, 2% Trenaxmine, 2% delay Electuary, 0.05% sodium hydrogensulfite, 0.4%1,2 hexylene glycols, 0.5%VC ethylether, 0.3% preservative, 2.8%KF-6017, 0.5%EM90,5%DC345,5% dimethyl silicone polymer, 2% carbonic acid dioctyl ester, the 1% poly- certain herbaceous plants with big flowers alkene of hydrogenation, 2% atoleine, 0.2% essence, 0.03% Goat Placenta hydrolysate, 0.3% nonapeptide -1,1% dipeptides -2,0.3% tetrapeptide -27,0.0014% iron oxide red, Surplus is deionized water.
3. whitening spot-eliminating composition according to claim 2, which is characterized in that the Goat Placenta hydrolysate is Goat Placenta-peptide Powder.
4. application of the whitening spot-eliminating composition described in Claims 2 or 3 in whitening spot-removing.
5. application of the whitening spot-eliminating composition described in Claims 2 or 3 in anti-aging.
CN201910125049.2A 2019-02-20 2019-02-20 A kind of whitening spot-eliminating composition Pending CN109602687A (en)

Priority Applications (1)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110522669A (en) * 2019-08-20 2019-12-03 浙江湃玥生物有限公司 It is a kind of effectively to inhibit beauty polypeptide enzymatic biodegrading process
CN111228184A (en) * 2020-03-26 2020-06-05 张虎 Moisturizing cosmetic composition and preparation method thereof
CN113662882A (en) * 2021-10-09 2021-11-19 上海新高姿化妆品有限公司 Whitening, spot-fading and tightening essence and preparation method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102488713A (en) * 2011-12-26 2012-06-13 重庆大学 Method for preparing sheep placenta extract and sheep placenta hydrolyzed collagen concentrated solution
CN103385843A (en) * 2013-07-22 2013-11-13 吴万有 Speckle-removing composition, preparation method thereof and applications thereof
CN107823095A (en) * 2017-12-07 2018-03-23 安徽生物肽产业研究院有限公司 A kind of active peptide facial mask
CN108096113A (en) * 2018-01-17 2018-06-01 王清秀 Goat Placenta-peptide composition, the facial mask liquid containing the Goat Placenta-peptide composition
CN108524382A (en) * 2018-07-25 2018-09-14 周恒� A kind of sunscreen spray and preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102488713A (en) * 2011-12-26 2012-06-13 重庆大学 Method for preparing sheep placenta extract and sheep placenta hydrolyzed collagen concentrated solution
CN103385843A (en) * 2013-07-22 2013-11-13 吴万有 Speckle-removing composition, preparation method thereof and applications thereof
CN107823095A (en) * 2017-12-07 2018-03-23 安徽生物肽产业研究院有限公司 A kind of active peptide facial mask
CN108096113A (en) * 2018-01-17 2018-06-01 王清秀 Goat Placenta-peptide composition, the facial mask liquid containing the Goat Placenta-peptide composition
CN108524382A (en) * 2018-07-25 2018-09-14 周恒� A kind of sunscreen spray and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王正坤: "《医学美容与皮肤保养》", 30 November 2013, 台海出版社 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110522669A (en) * 2019-08-20 2019-12-03 浙江湃玥生物有限公司 It is a kind of effectively to inhibit beauty polypeptide enzymatic biodegrading process
CN111228184A (en) * 2020-03-26 2020-06-05 张虎 Moisturizing cosmetic composition and preparation method thereof
CN113662882A (en) * 2021-10-09 2021-11-19 上海新高姿化妆品有限公司 Whitening, spot-fading and tightening essence and preparation method thereof

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Effective date of registration: 20190520

Address after: 528200 Room 215, 7 Royal Fort International Business Center, 15 Shilong North Road, Guicheng Street, Nanhai District, Foshan City, Guangdong Province

Applicant after: Guangdong Peptide Shijia Biotechnology Co., Ltd.

Address before: 510000 room 1216, 3 peace Middle Street, Guangzhou Avenue South, Guangzhou, Guangdong, Haizhuqu District

Applicant before: Wang Qingxiu

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Application publication date: 20190412

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