CN108686107B

CN108686107B - Chinese herbal medicine composition for promoting hair growth, preparation method and application thereof

Info

Publication number: CN108686107B
Application number: CN201810286904.3A
Authority: CN
Inventors: 刘玥劭
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-04-07
Filing date: 2018-03-30
Publication date: 2021-07-06
Anticipated expiration: 2038-03-30
Also published as: TW201836588A; CN108686107A; TWI708617B

Abstract

The present invention provides a Chinese herbal composition for promoting hair growth, comprising: the first kind of medicinal materials, the second kind of medicinal materials and the third kind of medicinal materials. The first kind of medicinal materials are lily, barbed skullcap herb, chaenomeles speciosa fruit, honeysuckle or any combination thereof; the second kind of medicinal materials is crocus; the third kind of medicinal materials is the mixture of the root and tender branch and leaf of arborvitae and black sesame; mixing the roots, tender branches and leaves of the arborvitae with the roots, barks, leaves and dry branches of the mulberry and the mulberry; purple grapes; or any combination thereof. Wherein, based on the total weight of the Chinese herbal medicine composition, the first medicinal material accounts for 2-40%, the second medicinal material accounts for 2-40%, and the third medicinal material accounts for 20-96%.

Description

Chinese herbal medicine composition for promoting hair growth, preparation method and application thereof

Technical Field

The invention relates to a Chinese herbal medicine composition, a preparation method and application thereof. In particular, it relates to a herbal composition for promoting hair growth and/or reducing hair loss, reducing scalp itching and/or reducing dandruff, improving mental condition, improving eyesight and/or improving skin condition, a preparation method and use thereof.

Background

The growth of hair requires blood to supply nutrients, which can lead to the risk of hair loss in the event of anemia. Because hair is one of the fastest growing parts of the body, when blood for supplying nutrition to hair is insufficient or deficient, the hair quickly shows the phenomena of poor hair quality, white hair, and even alopecia. The hair loss may be diagnosed as follows: male alopecia, round alopecia, alopecia caused by infection, alopecia caused by drugs, alopecia in telogen, alopecia cicatricta, etc. Among them, male baldness is the most common cause of hair loss, especially, modern people are under heavy pressure for life, and the risk of hair loss is aggravated by greasy diet, excessive hair blowing, and abnormal work and rest in night. Male baldness is usually caused by hormonal imbalance, adverse drug reactions, malnutrition, heredity, diseases, stress, cancer-related treatments and the like, and can be suffered by both men and women.

From the point of view of traditional Chinese medicine, whether the hair grows or fails is closely related to the blood. According to the book of the classic traditional Chinese medicine, "Suzhou, Liujie zang theory of visceral manifestation": in the kidney, the essence is also localized in the hair and filled in the bone. In addition to the discussion of "the kidney is in the state of being prosperous and has been in the beginning of the life", there are other traditional Chinese medical references that "the blood is exuberant and the hair is moist and the blood is weak and has been mentioned; therefore, the traditional Chinese medicine thinks that the hair is nourished by blood, and the key point of the good and bad hair lies in the kidney. Because kidneys store essence, they can transform into blood, and blood is exuberant, so they can moisten and beautify hair, so they are said to be kidney-blooming. The theory of traditional Chinese medicine has the expressions of "the excess of blood" and "the kidney is in the hair", so it is closely related to the kidney of traditional Chinese medicine; the expressions "excessive blood causes moistening and blood failure causes decline of hair", and "nutrient and blood deficiency and impairment of hair", which are closely related to the "blood" in Chinese medicine, are also described. Therefore, the principles of traditional medical treatment are mainly kidney-reinforcing and blood-nourishing. Young people are full of essence and blood, and hair is natural, glossy, black and moist; however, in the elderly, the hair is white due to essence and blood deficiency, and easily falls off, or the hair falls off and is sparse due to weakness caused by long-term diseases, and if the attention is paid to kidney tonifying, essence boosting and blood nourishing, the hair falling condition can be improved.

At present, the medicines approved by the American Food and Drug Administration (FDA) for treating hair loss are of two types, one is oral, the trade name is mild, but the medicines are only used for men; the first is external rubbing, the trade name is Jianjian, and the concentration is different. The hair loss can be stopped after 3 to 6 months of treatment, and the hair can grow after 1 to 2 years of taking. However, oral administration of drugs has the side effect of insufficient erectile rigidity, which causes troubles for some men.

The active ingredient of ROUPI and LONGJIAN is minoxidil (minoxidil). The mechanism of minoxidil for promoting hair growth is not completely understood, and the existing minoxidil (minoxidil) can promote hair follicles from a resting period to a growing period by expanding blood vessels and opening potassium ion channels so that more oxygen and nutrients are supplied to the hair follicles. However, other vasodilators do not have the same efficacy as minoxidil in stimulating hair growth. Since the mechanism of minoxidil for promoting hair growth is unknown, it also causes a hindrance to the development of a new related drug or formulation.

Thus, there remains a need for drugs or formulations that are fast acting, long lasting and have low side effects.

Disclosure of Invention

In view of the above-mentioned needs, the present invention relates to a Chinese herbal composition for promoting hair growth, comprising:

a first class of medicinal materials selected from the group consisting of lilies (genus lilium, scientific name:Lilium) And rhizoma gastrodiae (or named fengcao, academic name:Gastrodiaelata) And herba scutellariae barbatae (regenerated grass or Portulaca grandiflora, scientific name:Portulaca grandiflora) Chaenomeles speciosa (Sweet) Nakai) and ripe fruits of Chaenomeles speciosa (meditation) (c. sinensis (thuuin) Koehne) of the family rosaceae), Honeysuckle (honeyysuckle flower, scientific name:Lonicera japonicaThunb.)；

a second type of drug selected from the group consisting of rehmannia glutinosa (aka rehmanniae praeparata, scientific name:Rehmanniaglutinosa) Dodder seed (also known as devil's rush, academic name:Cuscutachinensis) Crocus sativus (also known as Saffron (safron), academic name:Crocus sativus）；

a third class of medicinal materials, which is:

mulberry;

root and tender leaves of Platycladus orientalis (Chinese Arborvitae twist and Leaf) ()Cacumen Platycladi) ) and mulberry;

purple grapes (academic name: Vitromanetii Roman. du Caill. ex Planch.) and mulberry; or

Root and tender branches and leaves of biota orientalis, black sesame (also known as Jusheng Zi or Pedalia cochinchinensis), purple grape and mulberry; wherein the mulberry is a mixture of mulberry (Wasabia chinensis, Chun Wu Shi) and mulberry root bark, leaves and dry branches.

In the Chinese herbal medicine composition of the present invention, the ratio of the first type of herbs, the second type of herbs and the third type of herbs is not limited, but based on the total weight of the Chinese herbal medicine composition, the first type of herbs preferably accounts for 2-40%, the second type of herbs preferably accounts for 2-40%, and the third type of herbs preferably accounts for 20-96%; more preferably, the first type of medicinal material accounts for 10-35%, the second type of medicinal material accounts for 10-30%, and the third type of medicinal material accounts for 35-80%; preferably, the first type of medicinal material accounts for 20-30%, the second type of medicinal material accounts for 20-25%, and the third type of medicinal material accounts for 45-60%.

In one embodiment, the third herb is a mixture of roots (cypress roots) and tender branches and leaves of biota orientalis and roots, leaves and dry branches of mulberries and mulberries, and the weight ratio of the roots and tender branches and leaves of biota orientalis to the roots, leaves and dry branches of mulberries and mulberries is expressed in proportion, i.e., the weight ratio is 0.8-1.2: 1, preferably 1: 1.

In another embodiment, the third herb is root, twig and leaf of biota orientalis; mulberry and its root bark, leaves and dry branches; and black sesame, and roots, tender branches and leaves of biota orientalis; mixing root bark, leaves and dry branches of mulberry and mulberry; and black sesame at a weight ratio of 1-4: 1, preferably 2: 2: 1.

In another embodiment, the third herb is mulberry and its root bark, leaves and dry branches; and purple grapes, wherein the weight ratio of the mulberry and the root bark, leaves and dry branches of the mulberry to the purple grapes is 0.8-1.2: 1, preferably 1: 1.

In another embodiment, the third herb is the root and tender branch of biota orientalis; mixing root bark, leaves and dry branches of mulberry and mulberry; purple grapes; and black sesame, and the roots and tender branches and leaves of biota orientalis; mixing root bark, leaves and dry branches of mulberry and mulberry; purple grapes; and the weight ratio of the black sesame to the black sesame is 1-5: 1, preferably 3: 3: 3: 1.

In an implementation mode, the first medicinal materials comprise lily, gastrodia elata, scutellaria barbata, chaenomeles speciosa and honeysuckle, and the weight ratio of the lily to the gastrodia elata to the scutellaria barbata to the chaenomeles speciosa to the honeysuckle is 1: 0.8: 1: 1: 1.2, wherein the honeysuckle not only provides curative effects, but also can be used as a natural preservative for external preparations.

In one embodiment, the second herb comprises radix rehmanniae Preparata, semen Cuscutae and stigma croci Sativi, and the weight ratio of radix rehmanniae Preparata, semen Cuscutae and stigma croci Sativi is 1.5: 1: 0.5.

In the Chinese herbal medicine composition of the invention, the third kind of medicinal materials can account for 100 percent, wherein, the composition is the mixture of roots and tender branches and leaves of arborvitae (with the scientific name: Platylladus orientalis (L.) Franco) and black sesame (with the scientific name: Semen sesami Nigrum); mixing root and tender branch and leaf of Chinese arborvitae (with scientific name: Fructus Mori) and root bark, leaf and dry branch of Mori Fructus; purple grapes (academic name: vitas romanetii Roman. du Caill. ex Planch.); or any combination thereof.

The Chinese herbal medicine composition of the invention can be selectively added with exterior syndrome relieving medicinal materials, diuretic medicinal materials, heat clearing medicinal materials or spleen strengthening and dampness eliminating medicinal materials according to the condition.

The Chinese herbal medicine composition is not limited in the addition amount of exterior syndrome relieving, diuretic, heat-clearing or spleen-strengthening and dampness-drying medicinal materials, preferably, the addition amount of exterior syndrome relieving medicinal materials is 1-50 wt%, the addition amount of diuretic is 1-50 wt%, the addition amount of heat-clearing medicinal materials is 1-70 wt%, and the addition amount of spleen-strengthening and dampness-drying is 1-40 wt%; more preferably, the exterior syndrome relieving medicinal material is preferably added in an amount of 5-30 wt%, the diuretic medicinal material is preferably added in an amount of 5-30 wt%, the heat-clearing medicinal material is preferably added in an amount of 5-50 wt%, and the spleen-invigorating and dampness-drying medicinal material is preferably added in an amount of 2-30 wt%.

The exterior syndrome relieving drug used selectively in the present invention can be any one of the conventional exterior syndrome relieving drugs preferably selected from the group consisting of: fermented soybean (Fermented soy bean), cassia twig (ramuscarinomomi), perilla (perillaceae folium), ginger (zingiberis rhizoma), ephedra (ephedra herba), onion stalk (allifistulosi Bulbus), notopterygium (Notopterygiirizoma) and combinations thereof.

The diuretic agent optionally used in the present invention may be any one of the known diuretic agents, preferably selected from the group consisting of: alismatis rhizoma (Alismatishrizoma), Semen plantaginis (Semen plantaginis), rhizoma Typhonii (Elephantopusscaber), Solanum nigrum (Solanum incanum), Poria (Indian buead), fructus Lipuidambaris (Beartiful sweet Fruit) and combinations thereof.

The heat-clearing drug optionally used in the present invention may be any one of the conventional heat-clearing drugs, and is preferably selected from the group consisting of: tamarix chinensis (Tamarix chinensis Lour.), Olive (Black Olive), Cassia Seed (Cassia Seed), pipewort (FlosEriocauli), lophatherum gracile (Sasagrass) and combinations thereof.

The spleen-invigorating and dampness-drying agent used selectively in the present invention is preferably any one of the conventional spleen-invigorating and dampness-drying agents, which has a fragrant smell, and is preferably selected from the group consisting of Gorgon euryale seed (euryaleferox Salisb.), Amomum kravanhPeel (Amomum kravanhPere ex Gagnep), Amomum tsao-koCrevost et Lemaire, Magnolia officinalis (Magnolia officinalis et. Wils.), Eupatorium fortunei (Eupatorium fortunei Turcz) and combinations thereof.

In the Chinese herbal medicine composition of the present invention, the exterior-releasing herbs are preferably ledebouriella root extract, fermented soybean extract, notopterygium root extract, or a combination thereof; the diuretic is preferably Alismatis rhizoma extract, caulis Clematidis Armandii extract, semen plantaginis extract or their composition; the heat-clearing medicinal material is preferably cortex moutan extract, herba Patriniae extract or their composition; the spleen-invigorating and dampness-eliminating medicinal materials are preferably gordon euryale seed extract, rhizoma atractylodis extract, zingiberaceae plant extract or a composition thereof.

The above herbs can be Chinese herbs, extracts of Chinese herbs, or mixtures thereof. In the case of the Chinese medicinal material extract, it is water extract, alcohol extract, or water extract and alcohol extract, and particularly, it is water extract and alcohol extract. The Chinese medicinal material extract is obtained by spray drying or freeze drying granulation.

As used herein, the term "promoting hair volume increase" is achieved by promoting hair growth and/or reducing hair loss, wherein preferably the hair growth is the original hair color hair growth, without wishing to be bound by theory, the herbal composition of the present invention retards aging and improves metabolism, the individual's white hair naturally falls off upon entering the resting phase of the hair growth cycle, and the newly formed hair is then the original hair color. Further, the herbal composition of the present invention has the effects of promoting an increase in the original hair color ratio of the whole hair (for example, if the individual is a black hair, the black hair ratio in the hair is increased), reducing scalp itching, balancing scalp oil and fat, removing odor and/or reducing dandruff. As used herein, the term "original hair color" refers to the color that appears before the hair is whitened, e.g., black, brown, gold, red, and the like. Further, the Chinese herbal composition of the present invention has the effects of improving mental condition, improving eyesight and/or improving skin conditions.

The Chinese herbal composition of the present invention is administered in a topical dosage form.

The Chinese herbal composition of the present invention can also be formulated into oral preparations, and other pharmaceutically acceptable carriers can also be added as required. For example, Chinese herbal compositions for oral administration may be in the form of capsules, lozenges, emulsions and liquid suspensions, dispersions and solvents. In the case of tablets, the carrier used is generally lactose or corn starch, a lubricant, or magnesium stearoyl as basic additives. In the form of oral capsules, effective diluents such as lactose and dried corn starch can be used. If desired, mild sweeteners, flavors may be added. The present invention preferably further comprises an excipient and the excipient suitable for use in the present invention may be any one of those conventionally used, preferably corn starch.

The invention also provides an oral health-care beverage for growing, nourishing and strengthening hair, which comprises the Chinese herbal medicine composition, water and optional fruit juice or fruit extract. In one embodiment of the oral health beverage for promoting hair growth, nourishing hair, strengthening hair and increasing hair, the Chinese herbal medicine composition of the invention is a distillate prepared by mixing or respectively preparing medicinal materials, the water is sterilized water or pure water, and the fruit is mulberry or grape. In a further embodiment, the weight percentages of the components based on the total weight of the oral health beverage for promoting hair growth, nourishing hair, strengthening hair and increasing hair can be shown in table 1.

TABLE 1 exemplary embodiments of oral hair growth, hair nourishing, hair health, and hair growth promoting health beverages

In another embodiment, the health beverage for promoting hair growth, nourishing hair, and strengthening hair can be further added with natural flavoring agent to improve palatability. For example, 0.1-1 c.c. longan honey is added to the mixed solution every 1000 c.c. of the mixed solution.

The present invention further provides a method for preparing the Chinese herbal composition as described above, comprising the steps of:

(a) providing the first type of herbs, the second type of herbs and the third type of herbs,

(b) mixing a first medicinal material, a second medicinal material and a third medicinal material to form a mixture, wherein the first medicinal material accounts for 2-40%, the second medicinal material accounts for 2-40%, and the third medicinal material accounts for 20-96% of the total weight of the Chinese herbal medicine composition,

(c) the mixture is extracted.

In addition, the above steps can also be obtained by mixing the raw materials according to different ratios, and then performing separate extraction, simultaneous extraction and concentration.

The present invention also provides the use of the above-mentioned Chinese herbal composition for the manufacture of a preparation for promoting hair volume increase, promoting increase of the primary color ratio of the whole hair, reducing scalp itching and/or reducing dandruff. As used herein, the term "promoting hair growth" refers to promoting hair growth, reducing hair loss, or both.

In one embodiment, the formulation is administered topically or orally through the skin.

In another embodiment, when the preparation is administered orally, the preparation further comprises an extract of Pogostemon cablin.

In one embodiment, the formulation uses water or an essential oil as a solvent.

In one embodiment, the honeysuckle in the preparation is used as a natural preservative for external use.

The foregoing description is only an overview of the technical solutions of the present invention, and in order to make the technical means of the present invention more clearly understood, the present invention may be implemented in accordance with the content of the description, and in order to make the above and other objects, features, and advantages of the present invention more clearly understood, the following preferred embodiments are described in detail with reference to the accompanying drawings.

Drawings

FIG. 1 is a photograph showing a comparison of the hair on the head and neck before and after the formula A2 is tried on by Mr. in the pool. In FIG. 1, the long hair span is seen in comparison to 1A and 1B, and the baldness span is more than halved.

FIG. 2 is a photograph showing a comparison of the top of the head and the back of the head of a human with Mr. huang after the trial of formulation A2.

FIG. 3 is a photograph showing a comparison of hair on the forehead of a trial person Miss Liu who tried formulation A3.

FIG. 4 is a photograph showing a comparison of hair on the head of Miss trial A4; in fig. 4, 4G and 4H are photographs of the hair on the posterior parietal brain.

FIG. 5 is a photograph showing a comparison of hair on the scalp of a person using Miss Liao after trial formula A4.

Fig. 6 is a photograph showing a comparison of the hair before and after the trial of the formula a5 by mr. queen.

Fig. 7 is a photograph of a comparison of hair and improvement before and after the trial with mr. a. mani trial with formulation a 5.

Fig. 8 is a photograph showing a comparison of hair and improvement of a human patient after trial of a formula a5 from mr. huang.

FIG. 9 is a comparative photograph of hair and improvement after Miss Zheng of test subject tried with formulation A5.

Detailed Description

The present invention is based on the preparation method of the traditional Chinese medicine in the known science, and the skilled person selects alcohol, water or the mixture of the alcohol and the water for extraction according to the characteristics of each medicinal material. The extracts obtained from the above herbs are combined into six formulas (shown in Table 2) according to different herbs and ratios, and then applied to the roots of the hair by the testers who have trouble in hair loss and slightly massaged for the tests.

TABLE 2 list of formulations used in the present invention

Arborvitae: containing root and tender branch and leaf

The amount of each spray is 0.25 ml, at least 3 ml-5 ml per day, and is applied 4 times per day (morning, noon, evening, before sleep), and if it cannot be applied regularly, the number of times can be deleted by self, such as morning and before sleep, but when the amount of each spray is 5ml, the total number of times per day is 20 sprays. If the medicine is used twice daily, the total dosage needs to be the same. The trial effect is 3 months, the usage amount is used as the evaluation standard, and the normal usage amount is used as the index of the effect generation speed (too small usage amount prolongs the effect reaction time, and the usage amount needs to be increased or decreased according to the individual bald area condition); the individual feeling of the test person is used as the therapeutic effect criterion. For scientific data, the effect is presented at 0-5 grade distance, and the observation indexes include four items of anti-alopecia, hair generation (new fine hair), black hair, mental status, skin complexion, etc.

Scoring Standard

0 point of no improvement

Score 1 improvement appears to be not very certain

2 score for improving

3 points that the medicine is improved

4 points of obvious improvement

5 points that the difference is very obviously improved or can be easily judged by the naked eyes of others

Example 1: single side

In this example, 5 volunteers were used for the test, and the mulberry extract was continuously tried out by the test patients and counted after three months (see table 3). The observation indexes include five items such as alopecia prevention, hair growth (new hair generation), hair blacking, mental status, skin complexion and the like. The scores are 0.8, 1, 0.6, 0.2, respectively, and the range of "improved and uncertain" seems to be. The embodiment proves that the folk explanation that the mulberry has no obvious effect of blackening hair and growing hair and improving eyesight by using about 270 ml to 450 ml (3 ml to 5ml per day) in three months, and the specific curative effect can be realized by matching with other medicinal materials.

TABLE 3

Example 2: testing the effectiveness of formulation A1

In this example, 5 volunteers were tested, and the formula A1 (shown in Table 2) was sprayed on the test subjects continuously, and the amount of the formula A1 was counted after 2 months according to the amount of about 150-. The observation indexes include five items such as alopecia prevention, hair growth (new hair generation), hair blacking, mental status, skin complexion and the like. The scores are respectively 3.8, 3.0, 1.8, 2.6, 2.0 and 1.8, wherein the curative effect of preventing alopecia is very remarkable; the hair growth (new fine hair), hair blackening, mental condition, and skin complexion are also improved. This example demonstrates that the herbal composition of the present invention has a far superior efficacy over a single mulberry drug.

TABLE 4

Example 3: testing the effectiveness of formulation A2

In this example, 6 volunteers were tested, and the formula A2 (shown in Table 2) was sprayed on the test subjects continuously, and the amount of the formula A2 was counted after 2 months as 150ml and 300 ml (shown in Table 5). The observation indexes include five items such as alopecia prevention, hair growth (new hair generation), hair blacking, mental status, skin complexion and the like. The scores are respectively 4.3, 3.8, 2, 2.7, 2.8 and 2.4, wherein the curative effect of preventing alopecia is very remarkable; the hair growth (new fine hair), hair blackening, mental condition, and skin complexion are also improved. This example demonstrates that the herbal composition of the present invention has a far superior efficacy over a single mulberry drug.

TABLE 5

The trial pool of this embodiment is 59 years old, and has alopecia of unknown reasons at the top of the head and alopecia of cerebral apoplexy type with alopecia capitis, and is established and administered for a long time. After 2150 ml of the formula A is tried, although hair still falls off, the bald part grows small and thin hair, and after about 75ml, the hair grows about 3.5-4 cm. The hair loss condition can be improved when 125 ml bald area is used, and the area when 150ml bald area is used is reduced, and the fine hair is thickened to 6-7.8 cm. The itching condition of the head is improved, and dandruff is reduced. (see 1A and 1B in FIG. 1).

The trial of this example shows that Mr. huang is 65 years old, and has hair loss due to unclear reasons of the head and the hindbrain, hair becomes more and more sparse, and baldness begins to appear in the center and the posterior center, and long-term use of Jian and Rui products is achieved. With A235 ml, the first week condition was not very obvious, with small fuzz development (2A and 2B in figure 2), and with 70ml more sensory hair growth of about 2-3 cm. In the third week, 125 ml is used, the hair grows faster on the top of the head, hair follicles occur on the right side of the back of the head, fine hair is more prominent, and the length of other long hairs is about 8-9 cm, as shown in fig. 2C. The bald part was improved.

Example 4: testing the effectiveness of formulation A3

In this example, 8 volunteer subjects were tested and sprayed with the formulation A3 of the present invention (shown in Table 2) continuously for 2 months, and then counted as about 150-. The observation indexes include five items such as alopecia prevention, hair growth (new hair generation), hair blacking, mental status/skin complexion, itching relieving and scurf stopping. The scores are respectively 4.5, 4.125, 3.875, 3.375, 3.5 and 3, wherein the curative effect of preventing alopecia and improving mental condition is very outstanding; the embodiment proves that the Chinese herbal medicine composition has the curative effect far superior to that of a single mulberry medicinal material.

TABLE 6

In the trial of this embodiment, the sister Liu, 50-year-old female, after the external uterine fibroid is cured by the operation for opening the surgical operation for 6 years, begins to have hair loss of unknown head and neck, the forehead hairline moves backwards, the hairline becomes wider and wider, the hair at the hair loss part becomes thinner and longer, and the hair begins to fall off about l-2 cm in length. Trial with the formula A250 ml, the hair loss condition is obviously reduced, the itching and dandruff condition of the scalp is improved, and the eyesight is improved. After 100ml of the product is tried, the hair on the neck is thickened and also has new fine hair, the hair grows for 3-4 cm, and the hair on the forehead is thickened. After the product is tried by 150ml, the hair loss is continuously and obviously reduced, the hair on the forehead and the neck becomes thick, the hair has a thick feeling, and the face color is ruddy before two weeks. Please refer to 3A-3D in FIG. 3, which are photographs of the hair on the head and forehead of a test person, Miss Liu, before the test of the formula A3 and after the test of 150ml (average 5ml per day).

Example 5: testing the effectiveness of formulation A4

In this example, 8 volunteer subjects were tested, and the subjects were sprayed with the formulation A4 (shown in Table 2) continuously, and counted after 2 months at a dosage of about 150-. The observation indexes include five items such as alopecia prevention, hair growth (new hair generation), hair blacking, mental status, skin complexion and itching and scurf stopping. The scores are respectively 3.8, 4, 4.28, 3.2, 4 and 3.3, wherein the curative effect of preventing alopecia and improving mental condition is very obvious; and also improve hair growth (new fine hair) and skin complexion. This example demonstrates that the herbal composition of the present invention has a far superior efficacy over a single mulberry drug.

TABLE 7

The Miss 26-year-old female of this example stopped menstruation and began to lose hair 4 years ago due to ovarian failure, lost hair did not grow back after the problem of menstruation was treated by the doctor, hair line seams began to become thicker and thicker, and alopecia began in the center. Recent detection to the center of health is follicle atrophy so that hair does not grow. Formulation A4 was tried voluntarily, using about 100ml (about 20 days on a normal basis). The improvement is shown in FIGS. 4A-4F and 4G-4H.

The trial Liao Miss 58 of the present example started to make thicker and thicker hair line due to aging, and started to use about 50ml (about 10 days per normal dose) of formula A4 in 5A and 5B of FIG. 5, it was found that the hair growth was about 5-6 cm after use, and the density still needs to be strengthened. 5C-5D in FIG. 5 may show the improvement; the hairline is reduced, and Liao Miss shows that the hair loss is reduced, and the effect is felt although the daily dosage is small.

Example 6: testing the effectiveness of formulation A5

In this example, 8 volunteers were tested, and the test subjects sprayed with the formulation A5 (Table 2) continuously for 2 months, and counted about 150-300 ml (see Table 8). The observation indexes include five items such as alopecia prevention, hair growth (new hair generation), hair blacking, mental status, skin complexion and itching and scurf stopping. The scores are respectively 4.375, 4.625, 3.875, 3.5 and 3.75, wherein the curative effect of preventing alopecia and improving mental condition is very outstanding; and also improve hair growth (new fine hair) and skin complexion. This example demonstrates that the herbal composition of the present invention has a far superior efficacy over a single mulberry drug.

TABLE 8

In the present embodiment, the hair of the patient is gradually thinned from more than 10 years ago, because fine hair is not grown and falls off, hair on the top of the head is thin, hair is not grown any more after the hair reaches a certain length, the top of the head is gradually bald, and the hair is diagnosed as male baldness by the medical doctor in the center of health care. After trial of 100ml of the formula A5, people feel very good to sleep, the whole people feel more active, the hair loss number is greatly reduced, the scalp itch and dandruff are also reduced, hair follicles are visible to be generated after the photos are enlarged, and hair is surely increased. The part of scalp which can not grow fine hair uniformly is increased by 7-8 cm. Fig. 6A, 6B, and 6C are photographs of the top of the head hair before mr. wang tried formulation a5 and after trial of 100ml and after trial of 250ml (about 50 days on normal use). His hindbrain spoons were also shown at 6D, 6E, 6F, and 6G, where 6D was prior to use, 6E was the result of trial 75ml (about 15 days normal), 6F was the result of trial 100ml (about 20 days normal), and 6G was the result of trial 200ml (about 40 days normal). 6H-6M is hair growth.

The subject of this example, Mr. Chua, a 65 year old male, had diluted hair over 20 years ago and had fallen for many years, and the entire head appeared to have no hair, but many fine hairs were still visible when examined with a scalp hair detector, but because the fine hairs could not grow or fall off, resulting in baldness, which is a typical symptom of male baldness and alopecia areata. Please compare the photographs of the hair at the

head part

7A and 7B in FIG. 7. Comparison of 7A with 7B shows that the hair grows faster under the back of the head, trying to 75ml (about 15 days), Mr. Chua shows that white hair is reduced, and black hair also grows, see 7C-7E in FIG. 7. 50ml of the formula A5 is tried on the upper part of the head, the spirit becomes good, the gas color becomes good in ruddy, and the fine hair visible to the naked eye appears at the original bright part of the head item when photographing and tracking (compared with 7F before use, the hair growth length increase from 7G and 7H is not fallen off, and black hair growth from 7K is visible). After 75ml had been used, the fine hair of the top was found to be significantly thicker, indicating that the anagen phase of the hair had been prolonged and not shed early. When 7L and 7M of the ginseng with enlarged pictures of bald parts have black hair and become activated hair capsules, the hair follicles generate black hair. The Chinese herbal composition of the present invention was shown to have a significant hair-repairing effect.

The trial of this example shows that Mr. huang 65 years old is after the hair of the previous trial formula A3 (not shown), but the hair follicle atrophy in the posterior cerebral part is severe, so that the thickening density is slightly insufficient, and after 550 ml of the formula A (about 10 days per normal dose), as shown in 8A-8E and 8C in FIG. 8, the hair follicle begins to grow fine at the severe part, the hair can continue to grow and no longer shed, and the bald area is reduced by about 1/2. As shown in FIGS. 8F and 8G, the hair grown on the parietal region became thick, dark and dense when viewed from the side. As shown in fig. 8E, the length of the lateral hairs exceeds 15cm and the lateral hairs are combed backward.

The trial of this example, Zheng Miss 53, also had thicker and thicker hair line on the top of the head, atrophy of hair follicles, and high working pressure (see 9A and 9B in FIG. 9). Severe hair loss about 75ml (about 15 days) after the trial of formulation A5 was seen to produce black hair and increased fullness with reduced hair loss (see 9C-9F in FIG. 9).

From the above test results, it is concluded that the herbal composition of the present invention not only can reduce hair loss, promote hair growth and blacken hair, but also can effectively improve mental status and skin complexion, and has more tonics than the single herbs of mulberry, black sesame and purple grape which are generally recognized to blacken hair and grow hair.

Furthermore, it should be noted that the above embodiments are only for illustration, but not for limiting the scope of the invention; for example: in the composition of table 2, the third group of herbs may account for 100%, and the main ingredients are: mixing root and tender branch of Chinese arborvitae with semen Sesami Niger; mixing the roots, tender branches and leaves of the arborvitae with the roots, barks, leaves and dry branches of the mulberry and the mulberry; purple grapes; or any combination thereof.

Although the present invention has been described with reference to a preferred embodiment, it should be understood that various changes, substitutions and alterations can be made herein without departing from the spirit and scope of the invention as defined by the appended claims.

Claims

1. A herbal composition for promoting hair growth, the composition comprising:

the first kind of medicinal materials including lily, gastrodia tuber, barbat skullcap, chaenomeles speciosa and honeysuckle;

the second kind of medicinal materials including saffron, prepared rhizome of rehmannia and dodder;

a third class of medicinal materials, which is:

mulberry;

root and tender branch and leaf of Chinese arborvitae, black sesame and mulberry;

root and tender branches and leaves of biota orientalis and mulberry;

purple grape and mulberry; or

Root and tender branch and leaf of Chinese arborvitae, black sesame, purple grape and mulberry;

wherein the mulberry is a mixture of mulberry and root bark, leaves and dry branches of the mulberry;

wherein, based on the total weight of the Chinese herbal medicine composition, the first medicinal material accounts for 2-40%, the second medicinal material accounts for 2-40%, and the third medicinal material accounts for 20-96%;

wherein the first, second and third herbs are Chinese medicinal materials, Chinese medicinal material extracts, or a mixture thereof, and the Chinese medicinal material extracts are water or alcohol extracts.

2. The herbal composition as claimed in claim 1, wherein the third herb is selected from the group consisting of roots and tender branches of biota orientalis; and mulberry, and their weight ratio is 0.8-1.2: 1.

3. The herbal composition of claim 1, wherein the third herb is selected from the group consisting of roots and shoots of biota orientalis; mulberry; and black sesame in a weight ratio of 1-4: 1.

4. The herbal composition of claim 1, wherein the third herb is selected from the group consisting of mulberry; and purple grapes in a weight ratio of 0.8 to 1.2: 1.

5. The herbal composition of claim 1, wherein the third herb is the root and tender branches and leaves of biota orientalis; mulberry; purple grapes; and black sesame at a weight ratio of 1-5: 1.

6. A method of preparing a herbal composition according to any one of claims 1 to 5, comprising the steps of:

(a) providing the first, second and third herbs as defined in claim 1,

(c) the mixture is extracted.

7. Use of a Chinese herbal composition according to any one of claims 1 to 5 for the manufacture of a preparation for promoting hair growth.

8. Use of a herbal composition according to any one of claims 1 to 5 for the manufacture of a preparation for promoting an increase in the proportion of the original hair color of the hair as a whole.