TW201836588A - Herbal composition for increasing hair volume and manufacturing method and using the same - Google Patents

Herbal composition for increasing hair volume and manufacturing method and using the same Download PDF

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TW201836588A
TW201836588A TW106111740A TW106111740A TW201836588A TW 201836588 A TW201836588 A TW 201836588A TW 106111740 A TW106111740 A TW 106111740A TW 106111740 A TW106111740 A TW 106111740A TW 201836588 A TW201836588 A TW 201836588A
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劉玥劭
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
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    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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Abstract

The present invention provides a herbal composition for increasing hair volume, comprising a first medicinal including Lily, Barbed skullcap herb, Carica papaya Linn, Honeysuckle flower, or any combinations thereof; a second medicinal material including Saffron; a third medicinal material including Chinese Arborvitae Twig and Leaf having its root, bark, and leaf combined with Black sesame, Chinese Arborvitae Twig and Leaf having its root, bark, and leaf combined with Mulberry having its root, leaf, and twig, Purple grape, or any combinations thereof; wherein the first medicinal material is 2~40%, the second medicinal material is 2~40%, and the third medicinal material is 20~96% based on the total weight of the herbal composition.

Description

用於促進髮量增加之中草藥組成物、其製備方法及用途    Chinese herbal medicine composition for promoting hair volume increase, preparation method and application thereof   

本揭露係有關於中草藥組成物、其製備方法及用途。特定言之,係指用於促進毛髮生長及/或減少毛髮掉落、促進頭髮烏黑、減少頭皮發癢、及/或減少頭皮屑、改善精神狀況、明目及/或改善膚質之中草藥組成物、其製備方法及用途。 This disclosure relates to Chinese herbal medicine composition, its preparation method and use. Specifically, it refers to the composition of Chinese herbal medicines used to promote hair growth and / or reduce hair fall, promote black hair, reduce itchy scalp, and / or reduce dandruff, improve mental health, eyesight and / or improve skin texture Material, its preparation method and use.

頭髮的生長需要血液供給養分,倘若一旦發生貧血,就會導致掉髮的危機。正因為頭髮是身體成長最快的部份之一,當供應頭髮營養的血液不足或有所缺損時,頭髮就會很快地呈現髮質變差、白髮,甚至脫髮的現象。掉髮約可能有下列診斷:雄性禿、圓禿、感染引起之禿髮、藥物引起之禿髮、休止期禿髮、瘢痕性禿髮等等。其中,雄性禿為最常見掉髮的原因,尤其現代人生活壓力大,飲食油膩、過度吹整頭髮、熬夜作息不正常,更加重了掉髮的危機。雄性禿比較多是荷爾蒙失調、藥物不良反應、營養不良、遺傳、疾病、壓力、接受癌症相關治療等產生,男女 均會罹患。 Hair growth requires blood to provide nutrients, and if anemia occurs, it will lead to the risk of hair loss. Because the hair is one of the fastest growing parts of the body, when the blood that supplies the hair is insufficient or defective, the hair will quickly show poor hair quality, gray hair, and even hair loss. Hair loss may have the following diagnoses: male baldness, round baldness, baldness due to infection, baldness due to medication, resting baldness, scarred baldness, and so on. Among them, male baldness is the most common cause of hair loss. Especially modern people have a lot of pressure on their lives, eating a greasy diet, excessively blowing their hair, and staying up late at night, which worsens the risk of hair loss. Male baldness is more often caused by hormonal disorders, adverse drug reactions, malnutrition, genetics, disease, stress, and receiving cancer-related treatments. Both men and women suffer from it.

從中西醫的觀點來看,頭髮生長盛衰與否,似與血液有著密不可分的關係。根據中醫典籍「素問.六節臟象論」記載:「腎者,精之處也,其華在髮,其充在骨」。除了「腎之華在髮」的論述之外,尚有其他的中醫典籍也曾提到「血盛則髮潤、血衰則髮衰」的說法;所以中醫認為頭髮受到血液的滋養,而頭髮的好與壞,其關鍵在於腎臟。因為「腎藏精,精能化血,精盛血旺,則毛髮潤澤美麗」,故說「腎之華在髮」。中醫理論有「髮為血之餘」、「腎之華在髮」之說法,所以主要跟『中醫的腎』有密切的關係;也有「血盛則髮潤、血衰則髮衰」、「營血虛損.....毛髮枯而不潤」的說法,也說明了與『中醫的血』息息相關。所以傳統醫學治療的原則以『固腎』、『補血』為主。年輕人精血充沛,毛髮自然光澤黑潤;而老年人精血虧虛,毛髮花白而易脫落,或久病體虛髮落稀疏,若能注意補腎、益精、養血,是可以改善落髮的情形。 From the point of view of traditional Chinese and Western medicine, the growth or decline of hair seems to have an inseparable relationship with blood. According to the classic Chinese medicine book "Su Wen. Six Sections of Visceral Theory": "The kidney is the essence, the essence is in the hair, the essence is in the bone." In addition to the discussion of "The kidney is blooming in hair," there are other TCM classics that have mentioned that "blood sheng is moist, and blood faint is faint." The key to good and bad lies in the kidneys. Because "the kidney hides its essence, it can turn blood into its essence, and its hair is moist and beautiful," so it says "the flower of the kidney is developing." The theory of traditional Chinese medicine includes the saying that "there is more than blood" and "the kidney is in bloom", so it has a close relationship with the "kidney of traditional Chinese medicine"; there are also "blood in the blood, but blood in the blood", The statement that the blood in the camp is damaged ... the hair is dry but not moist "also explains that it is closely related to the" blood of Chinese medicine ". Therefore, the principles of traditional medical treatment are "solid kidney" and "tonicate blood". Young people have plenty of fine blood, and the hair is naturally shiny and black; while the elderly have weak blood, white hair and easy to fall off, or sparse hair loss due to chronic illness, if you can pay attention to kidney, nourishing, and nourishing, you can improve the situation of hair loss .

目前美國食品藥物管制局〈FDA〉核准的治療掉髮藥物有兩類,一是口服的,商品名為柔沛,但只使用於男性;一是外擦的,商品名為落健,男女皆可使用,但濃度有差別。治療上通常需3至6個月,才能停止掉髮,服用1至2年才會長頭髮。可是口服的藥物會有勃起硬度不足的副作用,會造成某些男性的困擾。 At present, there are two types of hair loss drugs approved by the US Food and Drug Administration (FDA). One is oral, with the trade name Roupei, but it is only used by men. The other is external rubbing, with the trade name Loki. Use, but the concentration is different. It usually takes 3 to 6 months for treatment to stop hair loss, and it takes 1 to 2 years to grow hair. However, oral medications have the side effects of insufficient erectile stiffness, which can cause problems for some men.

柔沛及落健的活性成分為米諾地爾(minoxidil)。米諾 地爾促進毛髮生長的機轉目前還未完全了解,咸信米諾地爾(minoxidil)藉由擴張血管及開通鉀離子通道,使更多的氧氣及養分到毛囊,會促使毛囊從休止期到生長期。但,其他的血管擴張劑並沒有像米諾地爾一樣有刺激頭髮生長的功效。由於米諾地爾促進毛髮生長的機轉不明,因此也對開發新的相關藥物或製劑造成阻礙。 The active ingredient of Roupei and Jianjian is minoxidil. The mechanism of minoxidil to promote hair growth is not fully understood at present. Minoxidil expands blood vessels and opens potassium channels to allow more oxygen and nutrients to the hair follicles. Period to growth period. However, other vasodilators are not as effective at stimulating hair growth as minoxidil. Because the mechanism of minoxidil to promote hair growth is unknown, it also hinders the development of new related drugs or preparations.

因此,效果快、持續且副作用低的藥物或製劑仍有需求。 Therefore, there is still a need for drugs or formulations that are fast-acting, persistent, and have low side effects.

有鑑於上述之需求,本揭露係有關於一種用於促進髮量增加之中草藥組成物,其包含:第一類藥材,其係選自由百合(百合屬,學名:Lilium)、天麻(或名定風草,學名Gastrodia elata)、半枝蓮(又名再生草或大花馬齒莧,學名:Portulaca grandiflora)、宣木瓜(又名蓬生果,學名:Chaenomeles)、金銀花(Honeysuckle flower,學名Lonicera japonica Thunb.)及其任何混合所組成的群組;第二類藥材,其係選自由熟地(又名熟地黃,學名:Rehmannia glutinosa)、菟絲子(又名龍鬚子,學名:Cuscuta chinensis)、西紅花(又名番紅花(Saffron),學名:Crocus sativus)、及其任何混合所組成的群組;第三類藥材,其係選自由側柏葉(又名香柏(Chinese Arborvitae Twig and Leaf),學名:Platycladus orientalis (包括其根、柏根皮拉丁植物動物礦物名:latycladus orientalis(L.)Franco[Thujaorientalis L.;Biota orientalis(L.)ndl.],或是Cacumen Platycladi));桑葚(桑椹)(mulberry(包括其根白皮、葉、幹枝)又名文武實);黑芝麻(又名巨勝子或胡麻,學名:Sesamum indicum);紫葡萄(學名:Vitis romanetii Roman.du Caill.ex Planch.);及其任何混合所組成的群組。 In view of the above-described demand, the present disclosure relates to a system for promoting hair volume increasing the herbal composition, comprising: a first herbs which selected from the group consisting of lily (Lilium, scientific name: Lilium), Gastrodia (or name given Campanula , scientific name Gastrodia elata ), Scutellaria bark (also known as regenerated grass or Portulaca grandiflora , scientific name: Portulaca grandiflora ), Xuan papaya (aka Pengsheng fruit, scientific name: Chaenomeles), honeysuckle (Honeysuckle flower, scientific name Lonicera japonica Thunb.) And any combination thereof; the second type of medicinal materials is selected from the group consisting of cooked land (also known as Rehmannia glutinosa, scientific name: Rehmannia glutinosa ), Cuscuta (also known as dragon beard, scientific name: Cuscuta chinensis ), western Safflower (also known as Saffron, scientific name: Crocus sativus ), and any combination thereof; a third type of medicinal material selected from the group consisting of Platycladus orientalis leaves (also known as Chinese Arborvitae Twig and Leaf), Scientific name: Platycladus orientalis (including its roots, cypress roots, Latin plants, animals, mineral names: latycladus orientalis (L.) Franco [Thujaorientalis L .; Biota orientalis (L.) ndl.], Or Cac umen Platycladi )); mulberry (mulberry (including its root, white bark, leaves, dry branches), also known as Wen Wu Shi); black sesame (also known as giant fruit or flax, scientific name: Sesamum indicum ); purple grape (scientific name: Vitis romanetii Roman.du Caill.ex Planch.); and any mix of them.

本揭露之中草藥組成物中,第一類藥材、第二類藥材及第三類藥材之組成分比例不限,但以中草藥組成物總重量計,較佳為該第一類藥材占2~40%,該第二類藥材占2~40%,且該第三類藥材占20~96%;更佳為該第一類藥材占10~35%,該第二類藥材占10~30%,且該第三類藥材占35~80%;最佳為該第一類藥材占20~30%,該第二類藥材占20~25%,且該第三類藥材占45~60%。 In the Chinese herbal medicine composition disclosed in this disclosure, the composition ratios of the first class medicinal material, the second class medicinal material and the third class medicinal material are not limited, but based on the total weight of the Chinese herbal medicine composition, it is preferred that the first class medicinal material accounts for 2 to 40. %, The second type of medicinal materials accounts for 2 ~ 40%, and the third type of medicinal materials accounts for 20 ~ 96%; more preferably, the first type of medicinal materials accounts for 10 ~ 35%, and the second type of medicinal materials accounts for 10 ~ 30%, And the third type of medicinal materials accounts for 35 ~ 80%; the best is that the first type of medicinal materials accounts for 20-30%, the second type of medicinal materials accounts for 20-25%, and the third type of medicinal materials accounts for 45-60%.

在一實施態樣中,該第三類藥材係香柏之根(柏根)及嫩枝葉及文武實之根白皮(桑根白皮)、葉、及幹枝,香柏之根及嫩枝葉對文武實之根白皮、葉、及幹枝的重量比以比例示之,即,重量比係0.8~1.2:1,較佳為1:1。 In an embodiment, the third type of medicinal material is the roots (cedar roots) and tender branches and leaves of cedar, and the roots and leaves of mulberry (mulberry root), leaves, and dried branches, the roots and tender branches of cedar The weight ratio of the white bark, leaves, and dried branches of the military and military solids is shown in proportion, that is, the weight ratio is 0.8 to 1.2: 1, preferably 1: 1.

在另一實施態樣中,該第三類藥材係香柏之根、嫩枝葉;文武實及其根白皮、葉、及幹枝;及巨勝子,且香柏之根、嫩枝葉;文武實及其根白皮、葉、及幹枝;及巨勝子的重量比以比例示之,即,重量比係1~4:1~4:1,較佳為2:2:1。 In another embodiment, the third type of medicinal material is the roots, tender branches and leaves of cedar; Wenwushi and its roots, white bark, leaves, and dried branches; and Jushengzi, and the roots and tender leaves of cedar; Wenwushi The weight ratio of its roots, white bark, leaves, and dried branches; and Jushengzi are shown in proportion, that is, the weight ratio is 1 ~ 4: 1 ~ 4: 1, preferably 2: 2: 1.

在又一實施態樣中,該第三類藥材係文武實及其根白 皮、葉、及幹枝;及紫葡萄,且文武實及其根白皮、葉、及幹枝對紫葡萄的重量比係0.8~1.2:1,較佳為1:1。 In yet another aspect, the third type of medicinal material is Wenwushi and its root white bark, leaves, and dried branches; and purple grapes, and the weight ratio of Wenwushi and its root white bark, leaves, and dried branches to purple grapes The range is 0.8 to 1.2: 1, preferably 1: 1.

在又一實施態樣中,該第三類藥材係香柏之根及嫩枝葉;文武實及其根白皮、葉、及幹枝;紫葡萄;及巨勝子,且香柏之根及嫩枝葉;文武實及其根白皮、葉、及幹枝;紫葡萄;及巨勝子的重量比係1~5:1~5:1~5:1,較佳為3:3:3:1。 In yet another aspect, the third type of medicinal material is the roots and tender branches and leaves of Cedar; Wenwu Shi and its roots, white bark, leaves, and dried branches; purple grapes; and Jushengzi, and the roots and tender branches of Cedar The weight ratio of Wenwu Shi and its roots, white bark, leaves, and dried branches; purple grapes; and Jushengzi is 1 ~ 5: 1 ~ 5: 1 ~ 5: 1, preferably 3: 3: 3: 1.

在一實施態樣中,該第一類藥材中係百合、定風草、再生草、蓬生果、及金銀花,且百合、定風草、再生草、蓬生果、及金銀花的重量比係1:0.8:1:1:1.2,其中,該金銀花除提供療效之外,同時也可作為外用劑型天然防腐劑。 In an embodiment, the first class of medicinal materials is lily, hydrangea, regenerating grass, pungent fruit, and honeysuckle, and the weight ratio of lily, hydrangea, regenerating grass, pungent fruit, and honeysuckle is 1: 0.8: 1: 1: 1.2, in addition to providing curative effects, the honeysuckle can also be used as a natural antiseptic for external use.

在一實施態樣中,該第二類藥材中係熟地、龍鬚子、及西紅花,且熟地、龍鬚子、及西紅花的重量比係1.5:1:0.5。 In an implementation aspect, the second type of medicinal materials are cooked ground, dragon whisker, and safflower, and the weight ratio of cooked ground, dragon whisker, and safflower is 1.5: 1: 0.5.

本揭露之中草藥組成物更可視狀況選擇性地添加解表藥材、利尿藥材、清熱藥材或健脾燥濕藥材。 According to the present disclosure, the Chinese herbal medicine composition can selectively add medicinal herbs, diuretic medicinal herbs, heat-clearing medicinal herbs, or spleen dryness and dampness medicinal herbs depending on the situation.

本揭露之中草藥組成物所添加之解表藥材、利尿藥材、清熱藥材或健脾燥濕藥材之添加量不限,較佳的是,解表藥材添加量為1~50重量%,利尿藥材添加量為1~50重量%,清熱藥材添加量為1~70重量%,健脾燥濕添加量為1~40重量%;更佳的是,解表藥材較佳添加量為5~30重量%,利尿藥材較佳添加量為5~30重量%,清熱藥材較佳添加量為5~50重量%,健脾燥濕較佳添加量為2~30重 量。 There is no limit to the amount of anti-table medicine, diuretic medicine, heat-clearing medicine or spleen-drying and damp-wet medicine added to the Chinese herbal medicine composition. It is preferable that the amount of anti-table medicine is 1-50% by weight The amount is 1 to 50% by weight, the amount of heat-clearing medicinal materials is 1 to 70% by weight, and the amount of spleen, dryness and dampness is 1 to 40% by weight; more preferably, the amount of medicinal herbs to be added is 5 to 30% The preferred amount of diuretic medicinal materials is 5-30% by weight, the preferred amount of heat-clearing medicinal materials is 5-50% by weight, and the preferred amount of spleen and dryness is 2-30% by weight.

本揭露中選擇性使用之解表藥材可為任何一種習知解表藥材較佳係選自由下列藥材所組成之群組:淡豆豉(Fermented soybean)、桂枝(Ramulus cinamomi)、紫蘇(Perillae folium)、生薑(Zingiberis rhizoma)、麻黃(Ephedrae herba)、蔥白(Allii fistulosi Bulbus)、羌活(Notopterygii rhizoma)、及其組合物。 The medicinal herbs used in this disclosure may be any of the conventional medicinal herbs, preferably selected from the group consisting of: Fermented soybean, Ramulus cinamomi, Perillae folium ), Zingiberis rhizoma, Ephedrae herba, Allii fistulosi Bulbus, Notopterygii rhizoma, and combinations thereof.

本揭露中選擇性使用之利尿藥材可為任何一種習知利尿藥材,較佳係選自由下列藥材所組成之群組:澤瀉(Alismatis rhizoma)、車前子(Semen plantaginis)、丁豎杇(Elephantopus scaber)、黃水茄(Solanum incanum)、茯苓(Indian buead)、路路通(Beartiful sweetgum Fruit)、及其組合物。 The diuretic medicinal material selectively used in this disclosure may be any conventional diuretic medicinal material, and is preferably selected from the group consisting of the following medicinal materials: Alisatis rhizoma, Semen plantaginis, Ding Zhi Elephantopus scaber), Solanum incanum, Indian buead, Beartiful sweetgum Fruit, and combinations thereof.

本揭露中選擇性使用之清熱藥材可為任何一種習知清熱藥材,較佳係選自由下列藥材所組成之群組:檉柳(Tamarix chinensis Lour.)、橄欖(Black Olive)、決明子(Cassia Seed)、谷精草(Flos Eriocauli)、淡竹葉(Sasagrass)、及其組合物。 The heat-removing medicinal materials selectively used in this disclosure may be any conventional heat-reducing medicinal materials, preferably selected from the group consisting of the following medicinal materials: Tamarix chinensis Lour., Black Olive, Cassia Seed , Flos Eriocauli, Sasagrass, and combinations thereof.

本揭露中選擇性使用之健脾燥濕可為任何一種習知健脾燥濕藥材多具芳香之氣較佳係選自由下列藥材所組成之群組:芡實(Euryaleferox Salisb.)、白豆蔻(Amomum kravanh Piere ex Gagnep)、草果(Amomum tsao-ko Crevost et Lemaire)、厚朴(Magnolia officinalis Rehd.et Wils.)、佩蘭(Eupatorium fortunei Turcz)及其組合物。 The spleen dryness and dampness selectively used in this disclosure can be any of the conventional spleen dryness and dampness medicines. The aromatic aroma is preferably selected from the group consisting of Euryaleferox Salisb. And Amomum kravanh. Piere ex Gagnep), Amomum tsao-ko Crevost et Lemaire, Magnolia officinalis Rehd.et Wils., Eupatorium fortunei Turcz and combinations thereof.

本揭露之中草藥組成物中,解表藥材較佳為防風萃取物、淡豆豉萃取物、羌活萃取物、或其組合物;利尿藥材較佳為澤瀉萃取物、川木通萃取物、車前子萃取物或其組合物;清熱藥材較佳為牡丹皮萃取物、敗醬草萃取物或其組合物;健脾燥濕藥材較佳為芡實萃取物、蒼朮萃取物、姜科植物萃取物或其組合物。 In the Chinese herbal medicine composition disclosed in this disclosure, the antiemulsifying medicinal materials are preferably windproof extracts, light tempeh extracts, live extracts, or combinations thereof; the diuretic medicinal materials are preferably Alisma orientalis extract, Chuantongtong extract, and plantain Seed extract or composition thereof; the heat-clearing medicinal material is preferably peony skin extract, sage extract or its composition; the spleen-drying and dampness medicinal material is preferably Fructus Aurantii extract, Atractylodes root extract, ginger plant extract or Its composition.

上述之藥材,可為中藥材、中藥材萃取物、或其混合物。若為中藥材萃取物,係水萃取物、酒精萃取物、或水萃取物及酒精萃取物,特定言之,該中藥材萃取物係水萃取物及酒精萃取物。該中藥材萃取物係以噴霧乾燥或冷凍乾燥造粒而獲得。 The aforementioned medicinal materials may be Chinese medicinal materials, Chinese medicinal material extracts, or mixtures thereof. If it is a Chinese herbal medicine extract, it is a water extract, an alcohol extract, or a water extract and an alcohol extract. In particular, the Chinese herbal medicine extract is a water extract and an alcohol extract. The Chinese medicinal material extract is obtained by spray-drying or freeze-drying granulation.

如本文中所使用,用語「促進髮量增加」係藉由促進毛髮生長及/或減少毛髮掉落達成,其中,較佳的是,該毛髮生長係原來髮色毛髮生長,未欲受限於理論,咸信本揭露之中草藥組成物延緩老化及增進代謝,個體之白髮在進入毛髮生長周期休止期即自然掉落,接著,所新生的毛髮為原來髮色。進一步地,本揭露之中草藥組成物同時具有促進毛髮整體的原來髮色比例增加(舉例而言,個體若原為黑髮,則毛髮中的黑髮比例提高)、減少頭皮發癢、平衡頭皮油脂及去除異味、及/或減少頭皮屑之功效。如本文中所使用,用語「原來髮色」係指毛髮白化前所呈現之髮色,例如黑色、棕色、金色、紅色等等。又進一步地,本揭露之中草藥組成物同時具有改善精神狀況、明目及/或改善膚質之功效。 As used herein, the term "promote hair volume increase" is achieved by promoting hair growth and / or reducing hair fall. Among them, preferably, the hair growth is based on the original hair color hair growth, and is not intended to be limited by In theory, the Chinese herbal medicine composition disclosed by Xianxinben delays aging and enhances metabolism. The white hair of an individual falls naturally when it enters the telogen phase of hair growth. Then, the new hair is the original hair color. Further, the Chinese herbal medicine composition disclosed in the present disclosure also has an increase in the original hair color proportion of the entire hair (for example, if an individual is originally black, the proportion of black hair in the hair increases), reduces scalp itching, balances scalp oil, and Removes odors and / or reduces dandruff. As used herein, the term "original hair color" refers to the hair color that appears before the hair is whitened, such as black, brown, gold, red, and the like. Still further, the Chinese herbal medicine composition disclosed in the present disclosure has the effects of improving mental condition, eyesight and / or improving skin quality.

本揭露之中草藥組成物係以外用劑型投予。 The Chinese herbal medicine composition disclosed herein is administered in a dosage form for external use.

本揭露之中草藥組成物亦可經調製為口服製劑,且亦可依需要加入其他醫藥可接受之載體。例如,用於口服之中草藥組合物,型式包括膠囊、錠劑、乳化劑與液狀懸浮液、分散劑與溶劑。以錠片為例,一般所使用的載體為乳糖或是玉米澱粉,潤滑劑,或硬脂酰鎂為基木忝加物。以口服膠囊投藥型式,可以如乳糖與乾燥玉米澱粉等作為有效的稀釋液。如果需要,可添加適度的甜味劑,風味劑。本揭露中較佳更可包括一賦型劑而適用之賦型劑可為任一種習用者,較佳為玉米澱粉。 The Chinese herbal medicine composition disclosed in this disclosure can also be prepared as an oral preparation, and other medically acceptable carriers can be added as needed. For example, it is used for oral Chinese herbal medicine composition in the form of capsules, lozenges, emulsifiers and liquid suspensions, dispersants and solvents. Taking tablets as an example, the carrier generally used is lactose or corn starch, a lubricant, or magnesium stearate as a base wood additive. Oral capsules can be used as effective diluents such as lactose and dried corn starch. If necessary, moderate sweeteners and flavors can be added. A preferred excipient in this disclosure may include an excipient, and the suitable excipient may be any conventional user, preferably corn starch.

本揭露另提供一種口服生髮、養髮、健髮保健飲料,其包含上述之本揭露之中草藥組成物、水、及隨意之水果果汁或水果萃取液。在該口服生髮、養髮、健髮、增髮保健飲料的一實施態樣中,本揭露之中草藥組成物係藥材之混合製得或各別製得的蒸餾液,該水係滅菌水或純水,且該水果係文武實或葡萄。在進一步之實施態樣中,以該口服生髮、養髮、健髮、增髮保健飲料總重量計,各組分之重量百分比可如表1所示。 The disclosure also provides an oral hair growth, hair growth, and health care beverage, which comprises the Chinese herbal medicine composition, water, and fruit juice or fruit extract of the disclosure. In one embodiment of the oral hair growth, hair growth, healthy hair, and hair issuance health drink, the disclosed Chinese herbal medicine composition is a mixture of medicinal materials or a distillate prepared separately, and the water is sterilized water or pure Water, and the fruit is mandarin or grape. In a further embodiment, the weight percentages of the components based on the total weight of the oral hair growth, hair nourishing, hair strengthening, and hair issuance health drink can be shown in Table 1.

在又一實施態樣中,上述口服生髮、養髮、健髮、增髮保健飲料可另加入天然調味劑以增進嗜口性。例如,上述混合液再按混合液每1000c.c.加入0.1~1c.c.的龍眼蜜。 In yet another aspect, a natural flavoring agent may be added to the above-mentioned oral hair growth, hair conditioning, hair strengthening, and hair-increasing health drinks to improve palatability. For example, the above mixed solution is added with 0.1 to 1 c.c. of longan honey every 1000 c.c. according to the mixed solution.

本揭露另提供製備如上述之中草藥組成物之方法,其包含下列之步驟:(a)分別提供第一類藥材、第二類藥材、及第三類藥材,(b)將第一類藥材、第二類藥材、及第三類藥材混合以形成混合物,其中,以中草藥組成物總重量計,該第一類藥材占2~40%,該第二類藥材占2~40%,且該第三類藥材占20~96%,(c)萃取該混合物,其中該第一類藥材係選自由百合、定風草、再生草、蓬生果、金銀花及其任何混合所組成的群組,其中該第二類藥材係選自由熟地、龍鬚子、西紅花、及其任何混合所組成的群組,其中該第三類藥材係選自由香柏之根及嫩枝葉;文武 實及其根白皮、葉、及幹枝;紫葡萄;巨勝子;及其任何混合所組成的群組。 This disclosure also provides a method for preparing a Chinese herbal medicine composition as described above, which includes the following steps: (a) providing the first type of medicinal materials, the second type of medicinal materials, and the third type of medicinal materials, (b) combining the first type of medicinal materials, The second type of medicinal materials and the third type of medicinal materials are mixed to form a mixture, wherein, based on the total weight of the Chinese herbal medicine composition, the first type of medicinal materials accounts for 2 to 40%, the second type of medicinal materials accounts for 2 to 40%, and the first Three types of medicinal materials account for 20 ~ 96%, (c) extracting the mixture, wherein the first type of medicinal materials is selected from the group consisting of lily, hydrangea, regenerated grass, bonsai fruit, honeysuckle and any mixture thereof, wherein the The second type of medicinal material is selected from the group consisting of mature ground, dragon seed, safflower, and any mixture thereof, wherein the third type of medicinal material is selected from the roots and tender branches and leaves of cedar; Wenwushi and its root white bark , Leaves, and dried branches; purple grapes; giant fruit; and any combination thereof.

此外,前述之步驟中,也可依不同藥材配比混合,而後分開萃取、同時萃取、濃縮而獲得。 In addition, in the foregoing steps, it can also be obtained by mixing different medicinal materials and then separately extracting, extracting and concentrating at the same time.

本揭露亦提供如上述之中草藥組成物用於製造供促進髮量增加、促進毛髮整體的原來髮色比例增加、減少頭皮發癢及/或減少頭皮屑的製劑之用途。如本文中所使用,用語「促進髮量增加」係指促進毛髮生長、減少毛髮掉落、或同時有促進毛髮生長及減少毛髮掉落達成。 The present disclosure also provides the use of the Chinese herbal medicine composition as described above for manufacturing a preparation for promoting an increase in hair volume, promoting an increase in the original hair color proportion of the entire hair, reducing itchy scalp, and / or reducing dandruff. As used herein, the term "promoting hair growth" refers to promoting hair growth, reducing hair fall, or achieving both hair growth and reduction of hair fall.

在一實施態樣中,該製劑係經由皮膚外用或口服投予。 In one embodiment, the preparation is administered externally via the skin or orally.

在又一實施態樣中,該製劑係經由口服投予時,該製劑係另包含廣藿香萃取液。 In another embodiment, when the preparation is administered orally, the preparation further comprises patchouli extract.

在一實施態樣中,該製劑係以水或精油作為溶劑。 In one embodiment, the formulation uses water or essential oil as a solvent.

在一實施態樣中,該製劑中的金銀花係用以作為外用天然防腐劑。 In one aspect, the honeysuckle in the preparation is used as a natural preservative for external use.

圖1A至1B是試用者池先生試用配方A2前後之頭項部毛髮照片。圖1A與圖1B對照可看到長髮範圍,禿髮範圍縮小超過一半。 Figures 1A to 1B are photographs of the hair of the head of the trialer before and after the trial of Formula A2. The comparison between FIG. 1A and FIG. 1B shows the range of long hair, and the range of bald hair is reduced by more than half.

圖2A至2C分別為試用者黃先生試用配方A2後之頭頂及後腦勺毛髮照片。 Figures 2A to 2C are photos of the hair on the top of the head and on the back of the head after trial of Mr. Huang after using Formula A2.

圖3A至3D分別為試用者劉小姐試用配方A3前額部 毛髮照片。 Figures 3A to 3D are photos of the hair of the forehead of trial formula A3, which is used by the trial lady Ms. Liu.

圖4A至4H為試用者林小姐試用配方A4之頭項部毛髮照片;圖4G及4H為偏後腦頂部毛毛髮照片。 Figures 4A to 4H are photos of the hair on the head of the trialer Ms. Lin trying the formula A4; Figures 4G and 4H are photos of the hair on the top of the posterior brain.

圖5A至5D為試用者廖小姐試用配方A4後之頭項部毛髮照片。 Figures 5A to 5D are photos of the hair of the head of the trialer Ms. Liao after using Formula A4.

圖6A至6M分別為試用者王先生試用配方A5前後的毛髮照片。 Figures 6A to 6M are photos of hair before and after the trial by Mr. Wang, who tried Formula A5.

圖7A至7M為試用者蔡先生試用配方A5前後的毛髮照片及改善狀況。 Figures 7A to 7M are hair photos of Mr. Cai before and after the trial of Formula A5 and their improvement.

圖8A至8G為試用者黃先生試用配方A5後的毛髮照片及改善狀況。 Figures 8A to 8G are photos of Mr. Huang's hair after the trial of Formula A5 and its improvement.

圖9A至9F為試用者鄭小姐試用配方A5後的毛髮照片及改善狀況。 Figures 9A to 9F are photos of the tester Ms. Zheng after using Formula A5 and the improvement of the hair.

本揭露依照習知科學中藥的製備方式,熟習本技術領域者,依各藥材特性,選用酒精、水、或彼之混合物萃取。將自各藥材所獲得之萃取物,依不同藥材及配比組成六種配方(詳列如表2),再給予有落髮困擾之試用者噴在髮根並稍加按摩,進行試驗。 This disclosure is based on the traditional scientific method of preparing traditional Chinese medicine, and those skilled in the art will use alcohol, water, or a mixture of them for extraction according to the characteristics of each medicinal material. The extracts obtained from the various medicinal materials were composed into six formulas according to different medicinal materials and proportions (see Table 2 for details), and then the testers who had troubles with hair loss were sprayed on the roots of the hair and massaged slightly for testing.

每一噴灑量為0.25ml,每日至少3ml-5ml,每日施用4次(早、午、晚、睡前),如無法定時施用,可自行刪減次數,例如早上及睡前,但每次使用量為5ml時,則每日總次數為20噴次。如每日使用兩次則總和用量需相同。試用之效果以3個月並以使用量作為評量基準,以正規用量作為效用產生快不快速為指標(用量太少將效果反應時間拉長,須視個人髮禿面積情況加減用量);依試用者的個人感覺作為療效判定基準。為求科學化數據,茲將效果以0-5分級距呈現,且觀察指標計有防脫髮、生髮(新生細毛)黑髮、精神狀況、膚質氣色等四項。 Each spray volume is 0.25ml, at least 3ml-5ml daily, 4 times a day (morning, noon, evening, before bedtime). If you can't apply it regularly, you can delete the frequency yourself, such as in the morning and before bedtime, but every When the amount of use is 5ml, the total number of times per day is 20 sprays. If used twice a day, the total amount should be the same. The effect of the trial is 3 months and the usage amount is used as the evaluation benchmark, and the regular amount is used as an indicator of the effectiveness of the product. (Too little amount will lengthen the response time of the effect, and the amount should be increased or decreased depending on the individual's balding area); The individual's feeling is used as the benchmark for determining the efficacy. In order to obtain scientific data, the effect is presented in a step distance of 0-5, and the observation indicators include four items such as anti-hair loss, black hair (new-born fine hair), mental condition, and skin color.

《評分標準》     "Grading"    

0分:完全沒有改善 0 points: No improvement at all

1分:似乎有改善,不是很確定 1 point: seems to improve, not sure

2分:有改善 2 points: improvement

3分:確有改善 3 points: indeed improved

4分:明顯改善 4 points: Significant improvement

5分:極顯著改善或他人以肉眼可輕易判斷出不同 5 points: Very significant improvement or others can easily judge the difference with the naked eye

實施例1:單方Example 1: Unilateral

本實施例以5位志願試用者作測試,試用者連續試用文武實萃取液,三個月後作統計(詳見表3)。觀察指標計有防脫髮、生髮(新生細毛)、黑髮、精神狀況、以及膚質氣色等五項。其各項得分分別為0.8、1、1、0.6、0.6、 0.2分,「似乎有改善,不確定」之範圍內。本實施例驗證民間傳說文武實烏髮、長髮明目於三個月間用量約270ml-450ml(每日3ml-5ml)效果並不明顯,必須考慮配合其他藥材方能有較明確之療效。 In this embodiment, five volunteer trials are used for testing, and the trials continuously use Wenwushi extract, and statistics are made after three months (see Table 3 for details). Observation indicators include anti-hair loss, hair growth (new fine hair), black hair, mental condition, and skin color. Its scores were 0.8, 1, 1, 0.6, 0.6, and 0.2 points, respectively, within the range of "it seems to be improved and uncertain". This example verifies that the folklore of Wufa, Wufa and Changfengmu in the three months is about 270ml-450ml (3ml-5ml per day). The effect is not obvious. It must be considered in combination with other medicinal materials to have a clearer curative effect.

實施例2:測試配方A1之效果Example 2: Test the effect of Formula A1

本實施例以5位志願試用者作測試,試用者連續試用噴灑本發明配方A1(如表2),2個月後按用量約150-300ml作統計(詳見表3)。觀察指標計有防脫髮、生髮(新生細毛)、黑髮、精神狀況、以及膚質氣色等五項。其各項得分分別為3.8、3.0、1.8、2.6、2.0、1.8分,其中防脫髮之療效極為卓著;而生髮(新生細毛)、黑髮、精神狀況、以及膚質氣色等也確有改善的程度。本實施例證實本揭露之中草藥組成物具備遠優於單味文武實藥材的療效。 In this embodiment, 5 volunteer testers are used for testing, and the testers continuously spray the formula A1 of the present invention (as shown in Table 2), and the statistics are calculated based on the amount of about 150-300ml after 2 months (see Table 3 for details). Observation indicators include anti-hair loss, hair growth (new fine hair), black hair, mental condition, and skin color. Its scores are 3.8, 3.0, 1.8, 2.6, 2.0, and 1.8 respectively. Among them, the effect of preventing hair loss is outstanding; hair growth (new hair), black hair, mental condition, and skin color are also improved. degree. This example demonstrates that the Chinese herbal medicine composition disclosed in this disclosure has far better curative effect than the single-flavored Wenwu medicine.

實施例3:測試配方A2之效果Example 3: Test the effect of Formula A2

本實施例以6位志願試用者作測試,試用者連續試用噴灑本發明配方A2(如表3),2個月後按用量約150-300ml作統計(詳見表4)。觀察指標計有防脫髮、生髮(新生細毛)、黑髮、精神狀況、以及膚質氣色等五項。其各項得分分別為4.3、3.8、2、2.7、2.8、2.4分,其中防脫髮之療效極為卓著;而生髮(新生細毛)、黑髮、精神狀況、以及膚質氣色等也確有改善的程度。本實施例證實本揭露之中草藥組成物具備遠優於單味文武實藥材的療效。 In this embodiment, 6 volunteer testers are used for testing, and the testers continuously try and spray the formula A2 (as shown in Table 3) of the present invention, and the statistics are calculated based on the amount of about 150-300ml after 2 months (see Table 4 for details). Observation indicators include anti-hair loss, hair growth (new fine hair), black hair, mental condition, and skin color. Its scores are 4.3, 3.8, 2, 2.7, 2.8, and 2.4 respectively. Among them, the effect of preventing hair loss is outstanding; hair growth (new born fine hair), black hair, mental condition, and skin complexion have also improved. degree. This example demonstrates that the Chinese herbal medicine composition disclosed in this disclosure has far better curative effect than the single-flavored Wenwu medicine.

本實施例之試用者池先生59歲,從10多年前開始出現頭頂部不明原因脫髮,並出現腦溢型脫髮有頂禿現象,長期使用落建並服用柔沛。試用配方A2 150ml後,雖仍有掉髮但頂禿部分長出小細髮,大約75ml後頭髮長出約3.5-4cm。用到125ml禿髮範圍已都有細毛長出,落髮狀況也有改善,用到150ml禿的面積範圍縮小,細毛有變粗,長髮至6-7.8cm。頭部發癢情況改善,頭皮屑減少。(參見圖1A與1B)。 The tester of this example, Mr. Chi, was 59 years old. He had unexplained hair loss at the top of the head and had alopecia areata after a long period of use. After trying 150ml of Formula A2, although there is still hair loss, small hair grows on the bald part. About 75ml of hair grows about 3.5-4cm. With 125ml bald hair, fine hairs have grown, and hair loss has also improved. The area with 150ml bald hair has been reduced, and fine hairs have become thicker, with long hair up to 6-7.8cm. Itchy head is improved and dandruff is reduced. (See Figures 1A and 1B).

本實施例之試用者黃先生65歲,從20年前開始出現頭頂及後腦不明原因脫髮,頭髮越來越稀疏,開始中央及後中央呈現禿頭,長期使用落建及柔沛產品。使用A2 35ml,第一週狀況不是很明顯,有小細毛發生(如圖2A及2B),使用70ml較有感覺毛髮長出大約2-3cm。第三週,使用了125ml,頭頂上面部分頭髮生長較快長,後腦勺的右方毛囊發生,細毛較明顯,其他長髮長度約有8-9cm,如圖2C。禿頭部分確有改善。 The tester of this example, Mr. Huang, was 65 years old. He had unidentified hair loss at the top of the head and hindbrain 20 years ago, his hair became thinner and thinner, and he began to show baldness in the central and posterior centers. With 35ml of A2, the condition is not very obvious in the first week, and small hairs have occurred (as shown in Figures 2A and 2B). When using 70ml, the hair will feel about 2-3cm longer. In the third week, 125ml was used. The hair on the top of the head grew faster and longer, and the right hair follicles on the back of the head occurred. The fine hair was more obvious. The other long hair was about 8-9cm in length, as shown in Figure 2C. The bald part did improve.

實施例4:測試配方A3之效果Example 4: Test the effect of Formula A3

本實施例以8位志願受測者做測試,試用者連續試用噴灑本發明配方A3(如表2),2個月後按用量約150-300ml作統計(詳見表5)。觀察指標計有防脫髮、生髮(新生細毛)、黑髮、精神狀況/膚質氣色以及止癢止屑等五項。其各項得分分別為4.5、4.125、3.875、3.375、3.5、3分,其中防脫髮以及精神狀況改善之療效極為卓著;而生髮 (新生細毛、以及膚質氣色等也有改善。本實施例證實本揭露之中草藥組成物具備遠優於單味文武實藥材的療效。 In this embodiment, 8 volunteer test subjects are used for testing, and the tester continuously sprays the formula A3 of the present invention (as shown in Table 2), and the statistics are calculated based on the amount of about 150-300 ml after 2 months (see Table 5 for details). Observation indicators include five items such as hair loss prevention, hair growth (new fine hair), black hair, mental condition / skin color, and itching and dandruff. Its scores are 4.5, 4.125, 3.875, 3.375, 3.5, and 3 respectively. Among them, the effect of preventing hair loss and improving mental condition is outstanding; hair growth (new hair, and skin color, etc.) have also improved. It is revealed that the composition of Chinese herbal medicines has far better curative effect than that of single-medicine and military medicines.

本實施例之試用者劉小姐,53歲女性,從6年前子宮外肌瘤開刀手術治癒後開始出現頭項部不明原因脫髮,前額髮際線後移,髮際線越來越寬,脫髮部位的頭髮越長越細,且長度大約1-2cm左右就開始脫落。試用配方A2 50ml,自覺掉髮情況明顯減少,頭皮癢頭皮屑情況改善,明目。試用該產品100ml後,自覺頭項部細毛有變粗,也有新生細毛,頭髮有生長3-4cm,前額部頭髮亦有變粗現象。試用該產品150ml後,掉髮數持續明顯減少,前額部及項部頭髮變粗,頭髮較有豐厚感,面色較兩週前紅潤。請參見圖3A-3D,其分別為試用者劉小姐試用配方A3前、試用150ml(平均每日5ml)後之頭項及前額部毛髮照片。 The trial user of this example, Miss Liu, a 53-year-old female, began to have unexplained hair loss in the head and neck after the surgical treatment of extrauterine fibroids 6 years ago. The hair at the hair loss site becomes longer and thinner, and the hair starts to fall off about 1-2 cm in length. Trial formula A2 50ml, consciously reduced hair loss, scalp itching and dandruff situation improved, eyesight. After trying this product, 100ml, the fine hair on the head part became thicker and there were new hairs. The hair grew 3-4cm, and the hair on the forehead also became thicker. After trying this product 150ml, the number of hair loss continued to decrease significantly, the forehead and neck hair became thicker, the hair felt thicker, and the complexion was rosier than two weeks ago. Please refer to FIGS. 3A-3D, which are photos of the head and forehead hair of the trial lady, before trying Formula A3, after trying 150ml (average 5ml per day).

實施例5:測試配方A4之效果Example 5: Test the effect of Formula A4

本實施例以8位志願受測者做測試,試用者連續試用噴灑本發明配方A4(如表2),2個月後按用量約150-300ml作統計(詳見表6)。觀察指標計有防脫髮、生髮(新生細毛)、黑髮、精神狀況、膚質氣色以及止癢止屑等五項。其各項得分分別為3.8、4、4.28、3.2、4、3.3分,其中防脫髮以及精神狀況改善之療效極為卓著;而生髮(新生細毛)、以及膚質氣色等也有改善。本實施例證實本揭露之中草藥組成物具備遠優於單味文武實藥材的療效。 In this embodiment, 8 volunteer test subjects are used for testing, and the tester continuously sprays the formula A4 of the present invention (as shown in Table 2). After 2 months, the amount is about 150-300ml for statistics (see Table 6 for details). Observation indicators include anti-hair loss, hair growth (new fine hair), black hair, mental condition, skin color, and itching and dandruff. Its scores are 3.8, 4, 4.28, 3.2, 4, and 3.3 respectively. Among them, the effects of preventing hair loss and improving mental condition are outstanding; hair growth (new hair), and skin color are also improved. This example demonstrates that the Chinese herbal medicine composition disclosed in this disclosure has far better curative effect than the single-flavored Wenwu medicine.

本實施例之試用者林小姐26歲女性,4年前曾因卵巢問題停經並開始落髮,並在有停經問題由醫生醫治後其失去毛髮並未長回,髮際線縫開始越來越粗,中央有開始禿髮現象。近期至健髮中心檢測為毛囊萎縮以致頭髮不生。自願開始試用配方A4,使用約100ml(按正常用量約為20天)。圖片4A-4F及4G-4H可顯示其改善情況。 The 26-year-old Miss Lin, a trial user of this example, had menopause and began to lose hair 4 years ago due to ovarian problems, and lost her hair and did not grow back after having a menopause problem. In the center, there are elephants starting to find baldness. Recently, the hair follicles were detected by the Health Hair Center and the hair was not born. Voluntarily started trial of Formula A4, using about 100ml (about 20 days in normal dosage). Pictures 4A-4F and 4G-4H can show the improvement.

本實施例之試用者廖小姐58歲因老化原因,髮際線縫開始越來越粗,開始試用配方A4使用約50ml(按正常用量約為10天)圖5A及5B可看出使用後毛髮生長約5-6cm,濃密度仍須加強。圖5C-5D可顯示其改善情況;其髮際線較縮小,廖小姐表示,發現落髮减少,雖然每日用量很少,但覺得有效果。 The tester of this example, Ms. Liao, 58 years old, due to aging, her hairline began to become thicker and thicker. She started to use Formula A4 and used about 50ml (normally used for about 10 days). Figures 5A and 5B show the hair after use. Growing about 5-6cm, the density still needs to be strengthened. Figures 5C-5D can show the improvement; the hairline is narrower, Ms. Liao said that she found that hair loss is reduced. Although the daily dosage is small, it is effective.

實施例6:測試配方A5之效果Example 6: Test the effect of Formula A5

本實施例以8位志願受測者做測試,試用者連續試用噴灑本發明配方A5(表2),2個月後按用量約150-300ml作統計(詳見表7)。觀察指標計有防脫髮、生髮(新生細毛)、黑髮、精神狀況、膚質氣色以及止癢止屑等五項。其各項得分分別為4.375、4.375、4.625、3.875、3.5、3.75分,其中防脫髮以及精神狀況改善之療效極為卓著;而生髮(新生細毛)、以及膚質氣色等也有改善。本實施例證實本揭露之中草藥組成物具備遠優於單味文武實藥材的療效。 In this embodiment, 8 volunteer test subjects are used for testing, and the tester continuously sprays the formula A5 of the present invention (Table 2), and the statistics are calculated based on the dosage of about 150-300 ml after 2 months (see Table 7 for details). Observation indicators include anti-hair loss, hair growth (new fine hair), black hair, mental condition, skin color, and itching and dandruff. Its scores are 4.375, 4.375, 4.625, 3.875, 3.5, and 3.75 respectively. Among them, the effect of preventing hair loss and improving mental condition is outstanding; hair growth (new hair), and skin complexion are also improved. This example demonstrates that the Chinese herbal medicine composition disclosed in this disclosure has far better curative effect than the single-flavored Wenwu medicine.

本實施例之受試者王先生,54歲男性,從10多年前開始頭髮就漸漸稀疏,因為細毛無髮增長及脫落,頭頂毛髮稀少,並頭髮至一長度後,無法再長,後腦杓頂漸禿,健髮中心醫師診治認定為雄性禿。試用配方A5後100ml,覺得睡得很好,整個人覺得較有活力,掉髮數大為減少,頭皮癢、頭皮屑也減輕,照片放大可見毛囊有發生,頭髮確有增長。原本頭皮無法均勻長出細毛的部位已漸增長7-8cm。圖6A、6B及6C係王先生試用配方A5前及試用100ml後、及試用250ml(按正常用量約50天)的頭頂毛髮照片。他的後腦勺部位另參見圖6D、6E、6F、6G,其中,圖6D使用前,6E為試用量75ml(按正常用量約15天)的結果,圖6F為試用量100ml(按正常用量約20天)的結果,圖6G為試用量200ml(按正常用量約40天)的結果。圖6H-6M係毛髮生長情形。 The subject of this example, Mr. Wang, a 54-year-old male, has gradually thinned hair since more than 10 years ago, because the fine hair has no hair growth and shedding, and the hair on the top of the head is thin. After the hair reaches a length, it can no longer grow. Alopecia areata. Doctors at the Jianfa Center identified male as bald. After trying Formula A5 for 100ml, I felt that I slept well, the whole person felt more energetic, the number of hair loss was greatly reduced, the scalp itching and dandruff were also reduced, and the hair follicles were seen enlarged and the hair did grow. The part of the scalp where the fine hairs could not grow uniformly has gradually increased by 7-8cm. Figures 6A, 6B and 6C are photos of the hair on the head of Mr. Wang before trying Formula A5, after trying 100ml, and after trying 250ml (normally about 50 days). See also Figures 6D, 6E, 6F, and 6G for the back of his head. Among them, before using Figure 6D, 6E is the result of a trial volume of 75ml (about 15 days in normal dosage), and Figure 6F is a trial volume of 100ml (about 20 in normal dosage) Fig. 6G shows the result of a trial volume of 200 ml (about 40 days based on normal dosage). Figure 6H-6M hair growth.

本實施例之受試者蔡先生,65歲男性,從20多年前 頭髮漸稀,已經落髮多年,整個頭項看起來已經沒有頭髮,但以頭皮毛檢測儀檢視仍可看到許多細毛,只是因為細毛無法增長即脫落,故導致禿髮,此為雄性禿及斑禿的典型症狀。請比較圖7A及7B之頭項部毛髮照片。圖7A與7B對照可看出頭部後方下頭髮長出較快,試用到75ml(約15天),蔡先生表示其白髮減少,也有黑髮長出,請參見圖7C-7E。頭頂上方試用配方A5後50ml,精神變好,氣色紅潤變佳,拍照追蹤時發現頭項原光亮處有肉眼可見之細毛長出(比較使用前的圖7F,自圖7G、圖7H中可見生髮長度增長未脫落,自圖7K中可見黑髮生出)。使用至75ml後,發現頭項的細毛明顯變粗,這表示毛髮生長期已經延長,不會提早脫落。禿髮部分圖片放大參圖7L、圖7M已有黑細髮生出活化毛嚢後,毛囊發出黑細毛。顯示本揭露之中草藥組成物對於頭髮毛髮有明顯修護的效果。 The subject of this example, Mr. Cai, a 65-year-old male, has gradually thinned his hair from more than 20 years ago, and has lost hair for many years. The entire head appears to have no hair. Because fine hair cannot grow and fall off, it leads to baldness, which is a typical symptom of male baldness and alopecia areata. Compare the hair photos of the top of the head in Figures 7A and 7B. The comparison between Figures 7A and 7B shows that the lower hair behind the head grows faster. After trial use of 75ml (about 15 days), Mr. Cai said that his white hair is reduced and black hair is also grown. See Figure 7C-7E. At the top of the head, try 50ml of formula A5, the spirit becomes better, and the complexion becomes rosy. When photographing and tracking, it is found that fine hairs visible to the naked eye grow out of the head (see Figure 7F before use. The length did not fall off, and it can be seen from Figure 7K that black occurs). After using it to 75ml, the fine hair of the head item was noticeably thickened, which means that the hair growth has been prolonged for a long time, and it will not fall off early. The enlarged part of the bald hair is shown in FIG. 7L and FIG. 7M. After the black hairs have been activated, the hair follicles emit black hairs. It is shown that the Chinese herbal medicine composition disclosed in this disclosure has a significant effect on repairing hair.

本實施例之試用者黃先生65歲於先前試用配方A3生出毛髮後(未圖示),但後腦勺部位毛囊萎縮較嚴重致使濃密度略顯不足,改適用配方A5 50ml(按正常用量約10天)後如圖8A-8E,圖8C顯示毛囊萎縮嚴重處開始生出細毛,頭髮可以繼續增長不再脫落,禿髮的面積縮小約1/2。如圖8F及8G,以側面部位來看,頭頂項生出的細毛變粗變黑見濃密。如圖8E,可看出側髮長度已超過15cm以上,往後梳至後方。 The tester of this example, Mr. Huang, was 65 years old after he gave birth to hair in the previous trial of Formula A3 (not shown), but the hair follicles in the back of the head area were more severe, resulting in a slight lack of concentration. ), As shown in Figures 8A-8E, Figure 8C shows that the hair follicles are severely atrophied and begin to produce fine hair. The hair can continue to grow and not fall off, and the area of bald hair is reduced by about 1/2. As shown in Figures 8F and 8G, viewed from the side, the fine hairs from the top of the head become thicker and darker, and become denser. As shown in Figure 8E, it can be seen that the length of the side hair has exceeded 15 cm, and it is combed back to the back.

本實施例之試用者鄭小姐53歲也是頭頂白髮髮際線 越來越粗,毛囊萎縮,工作壓力大(參見圖9A及9B)。落髮嚴重試用配方A5後約75ml(大約15天)可看到其黑髮生出並頭髮減少脫落增加了豐厚感(參見圖9C-9F)。 The tester of this example, Ms. Zheng, 53 years old, also has thicker hairline at the top of her head, hair follicles shrink, and work pressure is high (see Figures 9A and 9B). About 75ml (about 15 days) of severe hair loss after trying Formula A5, it can be seen that the blackness occurs and the hair is reduced to increase the sense of richness (see Figures 9C-9F).

藉上述試驗結果可推知,本揭露中草藥組成物不僅可減少落髮,促使毛髮生長、黑髮,更可有效改善精神狀況以及膚質氣色,且超越一般認知用以烏髮生髮的文武實、巨勝子、紫葡萄單味補養藥甚多。 Based on the above test results, it can be inferred that the Chinese herbal medicine composition disclosed in this disclosure can not only reduce hair loss, promote hair growth and black hair, but also effectively improve mental condition and skin complexion, and go beyond the general cognition of the civil and military, giant winners that are used to produce hair. There are many single nourishing medicines for purple grapes.

上述實施例僅係為了方便說明而舉例而已,本揭露所主張之權利範圍自應以申請專利範圍所述為準,而非僅限於上述實施例。 The above embodiments are merely examples for the convenience of description. The scope of the rights claimed in this disclosure should be based on the scope of the patent application, rather than being limited to the above embodiments.

Claims (21)

一種用於促進髮量增加之中草藥組成物,其包含:第一類藥材,其係選自由百合百合屬(學名: Lilium)、天麻(學名: Gastrodia elata)、半枝蓮(Scutellaria barbata D.Don英文名:HERBASCUTELLARIAEBARBATAE、Barbed skullcap Herb)、宣木瓜(番木瓜科(Caricaceae)番木瓜屬(Carica)Common Floweringquince Fruit、金銀花(Honeysuckle flower)學名: Lonicera japonica Thunb.及其任何混合所組成的群組;第二類藥材,其係選自由熟地黃(Prepared rhizome of Adhesive Rehmannia)、菟絲子(South Dodder Seed,Chinese Dodder Seed,Semen Cuscutae.)、番紅花((Saffron學名: Crocus sativus)、及其任何混合所組成的群組;第三類藥材,其係選自由側柏( Platycladus orientalis(L.)Franco)之根,拉丁植物動物礦物名:latycladus orientalis(L.)Franco[Thujaorientalis L.;Biota orientalis(L.)Endl.]及嫩枝葉CACUMEN PLATYCLADI,Chinese Arborvitae Twig);黑桑葚(mulberry)(拉丁學名Fructus Mori r及其之根白皮桑白皮(Morus alba L.)、葉Folium Mori,Mulberry Leaf、及幹枝RAMULUS MORI,Mulberry Twig綜合屬桑科Moraceae);黑芝麻(Semen sesami Nigrum);紫葡萄((學名:Vitis romanetii Roman.du Caill.ex Planch.);及其任何混合所組成的群組, 其中,以中草藥組成物總重量計,該第一類藥材占2~40%,該第二類藥材占2~40%,且該第三類藥材占20~96%。 A Chinese herbal medicine composition for promoting hair loss, comprising: a first class of medicinal materials selected from the group consisting of Lilium (scientific name: Lilium ), Gastrodia (scientific name: Gastrodia elata ), Scutellaria barbata D. Don English name: HERBASCUTELLARIAEBARBATAE, Barbed skullcap Herb, Caricaceae (Caricaceae), Papaya (Carica) Common Floweringquince Fruit, Honeysuckle flower Scientific name: Lonicera japonica Thunb. And any combination thereof ; The second type of medicinal materials is selected from the group consisting of Prepared rhizome of Adhesive Rehmannia, South Dodder Seed, Chinese Dodder Seed, Semen Cuscutae., Saffron ((Saffron scientific name: Crocus sativus ), and any mixture thereof) The third group of medicinal materials is selected from the roots of Platycladus orientalis (L.) Franco, the Latin plant animal mineral name: latycladus orientalis (L.) Franco [Thujaorientalis L .; Biota orientalis ( L.) Endl.] And CACUMEN PLATYCLADI, Chinese Arborvitae Twig); mulberry (Fructus Mori r and its scientific name) Root White Peel Morus alba L., leaves Folium Mori, Mulberry Leaf, and dried branches RAMULUS MORI, Mulberry Twig are genus Moraceae; Black Sesame (Semen sesami Nigrum); Purple Grape ((Scientific name: Vitis romanetii Roman.du Caill.ex Planch.); and any mixture thereof, in which, based on the total weight of the Chinese herbal medicine composition, the first type of medicinal materials accounts for 2 ~ 40%, and the second type of medicinal materials accounts for 2 ~ 40%, and the third type of medicinal materials account for 20 ~ 96%. 如請求項1之中草藥組成物,其中該第三類藥材係由香柏之根及嫩枝葉;及文武實之根白皮、葉、及幹枝組成,且彼等重量比係0.8~1.2:1。     For example, the Chinese herbal medicine composition according to claim 1, wherein the third type of medicinal material is composed of the roots and tender branches and leaves of cedar; and the white skin, leaves, and dried branches of the roots of martial arts, and their weight ratio is 0.8 ~ 1.2: 1.     如請求項1之中草藥組成物,其中該第三類藥材係由香柏之根、嫩枝葉;文武實之根白皮、葉、及幹枝;及巨勝子組成,且彼等重量比係1~4:1~4:1。     For example, the Chinese herbal medicine composition of claim 1, wherein the third type of medicinal materials is composed of the roots and tender branches and leaves of the cedar; the white peel, leaves, and dried branches of the roots of martial arts; and Jushengzi, and their weight ratio is 1 ~ 4 : 1 ~ 4: 1.     如請求項1之中草藥組成物,其中該第三類藥材由文武實之根白皮、葉、及幹枝;及紫葡萄組成,且彼等重量比係0.8~1.2:1。     For example, the Chinese herbal medicine composition of claim 1, wherein the third type of medicinal material is composed of roots, skins, leaves, and dried branches; and purple grapes, and their weight ratio is 0.8 ~ 1.2: 1.     如請求項1之中草藥組成物,其中該第三類藥材係香柏之根及嫩枝葉;文武實之根白皮、葉、及幹枝;紫葡萄;及巨勝子,且彼等之重量比係1~5:1~5:1~5:1。     For example, the Chinese herbal medicine composition of claim 1, wherein the third type of medicinal material is the roots and tender branches and leaves of cedar; the white peel, leaves, and dried branches of the roots of martial arts; purple grapes; and Jushengzi, and their weight ratio is 1 ~ 5: 1 ~ 5: 1 ~ 5: 1.     如請求項1之中草藥組成物,其中該第一類藥材係百合、定風草、再生草、蓬生果、及金銀花,且百合、定風草、再生草、蓬生果、及金銀花的重量比係1:0.8:1:1:1.2。     For example, the Chinese herbal medicine composition of claim 1, wherein the first type of medicinal materials is lily, hydrangea, regenerating grass, pungent fruit, and honeysuckle, and the weight ratio of lilies, hydrangea, regenerating grass, pungent fruit, and honeysuckle is 1: 0.8: 1: 1: 1.2.     如請求項1至6中任一項之中草藥組成物,其中該藥材係中藥材、中藥材萃取物、或其混合物。     The Chinese herbal medicine composition according to any one of claims 1 to 6, wherein the medicinal material is a Chinese medicinal material, a Chinese medicinal material extract, or a mixture thereof.     如請求項7之中草藥組成物,其中該中藥材萃取物係水萃取物、酒精萃取物、或水萃取物及酒精萃取物。     The Chinese herbal medicine composition according to claim 7, wherein the Chinese medicinal material extract is a water extract, an alcohol extract, or a water extract and an alcohol extract.     如請求項8之中草藥組成物,其中該中藥材萃取 物係水萃取物及酒精萃取物。     The Chinese herbal medicine composition according to claim 8, wherein the Chinese herbal medicine extract is a water extract and an alcohol extract.     如請求項7之中草藥組成物,其中該中藥材萃取物係以噴霧乾燥或冷凍乾燥造粒而獲得。     The Chinese herbal medicine composition according to claim 7, wherein the Chinese herbal medicine extract is obtained by spray-drying or freeze-drying granulation.     如請求項1至6中任一項之中草藥組成物,其中該促進髮量增加係藉由促進毛髮生長及/或減少毛髮掉落達成。     The Chinese herbal medicine composition according to any one of claims 1 to 6, wherein the increase in hair volume is achieved by promoting hair growth and / or reducing hair fall.     如請求項1至6中任一項之中草藥組成物,其中該中草藥組成物同時具有促進毛髮整體的原來髮色比例增加、減少頭皮發癢、及/或減少頭皮屑之功效。     The Chinese herbal medicine composition according to any one of claims 1 to 6, wherein the Chinese herbal medicine composition simultaneously has the effects of promoting an increase in the original hair color proportion of the entire hair, reducing itchy scalp, and / or reducing dandruff.     如請求項1至6中任一項之中草藥組成物,其中該中草藥組成物同時具有改善精神狀況、明目及/或改善膚質之功效。     The Chinese herbal medicine composition according to any one of claims 1 to 6, wherein the Chinese herbal medicine composition has the effects of improving mental condition, eyesight and / or improving skin quality.     如請求項1至6中任一項之中草藥組成物,其中該中草藥組成物係以外用劑型投予。     The Chinese herbal medicine composition according to any one of claims 1 to 6, wherein the Chinese herbal medicine composition is administered in a dosage form for external use.     一種製備如請求項1至14中任一項之中草藥組成物之方法,其包含下列之步驟:(a)分別提供第一類藥材、第二類藥材、及第三類藥材,(b)將第一類藥材、第二類藥材、及第三類藥材混合以形成混合物,其中,以中草藥組成物總重量計,該第一類藥材占2~40%,該第二類藥材占2~40%,且該第三類藥材占20~96%,(c)萃取該混合物,其中該第一類藥材係選自由百合、定風草、再生草、 蓬生果、金銀花及其任何混合所組成的群組,其中該第二類藥材係選自由熟地、龍鬚子、西紅花、及其任何混合所組成的群組,其中該第三類藥材係選自由香柏之根及嫩枝葉;文武實之根白皮、葉、及幹枝;紫葡萄;巨勝子;及其任何混合所組成的群組。     A method for preparing a Chinese herbal medicine composition according to any one of claims 1 to 14, comprising the following steps: (a) providing a first type of medicinal material, a second type of medicinal material, and a third type of medicinal material, (b) adding The first type of medicinal materials, the second type of medicinal materials, and the third type of medicinal materials are mixed to form a mixture, wherein, based on the total weight of the Chinese herbal medicine composition, the first type of medicinal materials accounts for 2 to 40%, and the second type of medicinal materials accounts for 2 to 40. %, And the third type of medicinal material accounts for 20 ~ 96%, (c) extracting the mixture, wherein the first type of medicinal material is selected from the group consisting of lily, hydrangea, regenerated grass, pungent fruit, honeysuckle and any mixture thereof Group, wherein the second type of medicinal material is selected from the group consisting of cooked land, dragon seed, safflower, and any mixture thereof, wherein the third type of medicinal material is selected from the root and tender branches of Cedar; Roots of white bark, leaves, and dried branches; purple grapes; giant fruit; and any combination thereof.     一種如請求項1至14中任一項之中草藥組成物用於製造供促進髮量增加的製劑之用途。     A Chinese herbal medicine composition according to any one of claims 1 to 14 for use in the manufacture of a preparation for promoting an increase in hair volume.     如請求項16之用途,其中該促進髮量增加係藉由促進毛髮生長及/或減少毛髮掉落達成。     The use as claimed in claim 16, wherein the increase in hair volume is achieved by promoting hair growth and / or reducing hair fall.     一種如請求項1至14中任一項之中草藥組成物用於製造供促進毛髮整體的原來髮色比例增加的製劑之用途。     A Chinese herbal medicine composition according to any one of claims 1 to 14 for use in the manufacture of a preparation for promoting an increase in the proportion of the original hair color of the entire hair.     一種如請求項1至14中任一項之中草藥組成物用於製造供減少頭皮發癢、平衡頭皮油脂及去除異味、及/或減少頭皮屑的製劑之用途。     A Chinese herbal medicine composition according to any one of claims 1 to 14 for use in the manufacture of a preparation for reducing itching of the scalp, balancing scalp oils and fats, removing odors, and / or reducing dandruff.     如請求項16至19中任一項之用途,其中該製劑係經由皮膚外用或口服投予。     The use according to any one of claims 16 to 19, wherein the preparation is administered externally through the skin or orally.     如請求項16至19中任一項之用途,其中該製劑係以水或精油作為溶劑。     The use according to any one of claims 16 to 19, wherein the preparation is water or an essential oil as a solvent.    
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