CN101524437A - Chinese medicinal composition for treating female anemia and preparation method thereof - Google Patents
Chinese medicinal composition for treating female anemia and preparation method thereof Download PDFInfo
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- CN101524437A CN101524437A CN200810101474A CN200810101474A CN101524437A CN 101524437 A CN101524437 A CN 101524437A CN 200810101474 A CN200810101474 A CN 200810101474A CN 200810101474 A CN200810101474 A CN 200810101474A CN 101524437 A CN101524437 A CN 101524437A
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Abstract
The invention relates to a Chinese medicinal composition for treating female anemia, which is prepared from ginseng, radix astragali, cooked rehmannia, largehead atractylodes rhizome, Indian buead, Chinese angelica, cinnamon, white paeony root, mix-fried licorice, szechuan lovage rhizome and yanhusuo, and is prepared into one clinically acceptable formulation of granular formulation, tablet formulation and capsule formulation by processing technology such as extraction, concentration, drying and the like. The Chinese medicinal composition has the efficacies in tonifying the heart, nourishing the liver and generating blood, and invigorating the vital energy, nourishing the blood and growing hair, is used for treating Qi and blood deficiency with the symptoms of sallow or pale and dim complexion, insomnia, dizziness and acroanesthesia, and is suitable for female with little menstrual blood with light color or opsomenorrhea. The invention also relates to a preparation method for the Chinese medicinal composition.
Description
Technical field:
The invention belongs to technical field of traditional Chinese medicine pharmacy, be specifically related to a kind of Chinese medicine composition for the treatment of female anemia, the invention still further relates to the preparation method of this Chinese medicine composition.
Technical background
Anemia is a more common disease in the life, and exactly, anemia is a kind of symptom, rather than concrete disease, and various diseases can be with anemia.
Ministry of Health of China is at female anemia situation statistics at reproduction age: the near female anemia at reproduction age of half! Wherein: 64.5% conceived female anemia, 61.3% lactating female anemia.
Anemia generally shows palor and lusterless complexion, and fingernail, skin of palm of hand and lip mucosa, eyes palpebral conjunctiva are pale; Tired, weak, dizzy, tinnitus, hypomnesis, absent-minded etc. all be the early stage and common symptom of anemia; Take offence urgency, cardiopalmus etc. of light work also are that symptom is often arranged.In addition, also have inappetence, nausea,vomiting,diarrhea, abdominal distention, with symptoms such as glossitis, tongue fur light are red.If there is obvious haemolysis performance that the skin mucosa xanthochromia can be arranged.
Symptom: hair rareness gradually comes off, very then eyebrow, armpit hair, pubes also simultaneously rareness come off.Be partial to blood deficiency person, shallow complexion or light simple and unadorned in vain, the lip onyx is light white, insomnia, dizziness, order is stuck with paste, the limb fiber crops.The women is few through blood volume, and color is light or delayed period is unlikely, even amenorrhea, pale tongue with thin fur, thready pulse without strength.Be partial to deficiency of vital energy person, spiritlessness and weakness, deficiency of QI with disinclination to talk, spontaneous perspiration is had a dizzy spell, light red tongue or the light fat indentation that has, thready pulse or empty soft unable.QI and blood deficiency person, pale white complexion or sallow, the lips and nails being pale, spiritlessness and weakness, deficiency of QI with disinclination to talk, spontaneous perspiration, palpitation and insomnia, two dryness and uneasy feeling of the eye, or limb muscle numbness, intercalation moving, wriggling, women's menstrual blood volume is few, and tongue body is thin thin, and perhaps lingual surface has crackle, and tongue is few, deficient and thready pulse and unable.
The traditional Chinese medical science thinks that asthenia of qi and blood loses, and can not go up Rong Yufa, sends out to lose and nourishes, so day by day rareness comes off.QI and blood deficiency, the whole body hair is all become homeless foster, so very then eyebrow, armpit hair, pubes while rareness come off.Then promotion of the deficiency of vital energy, astringency inducing, gasification function weaken, spiritlessness and weakness then, deficiency of QI with disinclination to talk, spontaneous perspiration.The visible order of blood deficiency is stuck with paste, two dryness and uneasy feeling of the eye, insomnia, cardiopalmus, numb limbs and tense tendons, intercalation moving, wriggling.Dash to appoint to lose and support, visible menstrual blood volume is few.Tongue body is thin thin, and deficient and thready pulse is unable.Be the card of QI and blood deficiency.
The present invention forms according to Traditional Chinese medical theory basis set modern Chinese medicine clinical experience, and Radix Ginseng, the Radix Astragali, Radix Rehmanniae Preparata have the effect of sweet temperature benefiting QI and nourishing blood in the side; The Rhizoma Atractylodis Macrocephalae has the effect of warm the spleen strengthening and damp drying, the sweet light strengthening the spleen eliminating dampness by diuresis of Poria, and Radix Angelicae Sinensis, Radix Paeoniae Alba nourish blood and seek, Radix Glycyrrhizae Preparata and middle QI invigorating, Rhizoma Chuanxiong blood-activating and qi-promoting.Above-mentioned medical material has the effect of beneficial heart nourishing the liver hemopoietic, benefiting qi and nourishing blood hair growth promoting behind compatibility, be used for deficiency of qi and blood, the sallow or light white simple and unadorned insomnia of disease meeting color, and dizziness, order is stuck with paste, the limb fiber crops.The women is few through blood volume, the light or unlikely person of delayed period of color.
Summary of the invention:
One of purpose of the present invention provides a kind of Chinese medicine composition for the treatment of female anemia.
Another purpose of the present invention provides the preparation method of this Chinese medicine composition.
Chinese medicine of the present invention is made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made (part is unit of weight) by following raw materials according:
1, prescription:
Radix Ginseng 150-300 part Radix Astragali 150-300 part Radix Rehmanniae Preparata 150-300 part
Rhizoma Atractylodis Macrocephalae 100-300 part Poria 100-200 part Radix Angelicae Sinensis 100-200 part
Cortex Cinnamomi 100-200 part Radix Paeoniae Alba 100-200 part Radix Glycyrrhizae Preparata 100-300 part
Rhizoma Chuanxiong 50-100 part Rhizoma Corydalis 100-200 part
The active component that preferred following raw materials according is made, curative effect is better:
200 parts of 150 parts of Radix Rehmanniae Preparata of 150 parts of Radixs Astragali of Radix Ginseng
100 parts of 100 parts of Radix Angelicae Sinensis of 150 parts of Poria of the Rhizoma Atractylodis Macrocephalae
150 parts of 100 parts of Radix Glycyrrhizae Preparatas of 100 portions of Radix Paeoniae Albas of Cortex Cinnamomi
100 parts of 80 parts of Rhizoma Corydalis of Rhizoma Chuanxiong
The active ingredient preparation method of Chinese medicine of the present invention can be that raw material is dry respectively, and levigation mixes.It also can be the conventional method preparation of adopting herbal pharmaceutical.These pharmacy conventional methods can be water extract-alcohol precipitation or ethanol extract from water precipitation, also have other extracting method in addition, specifically " pharmaceutics of Chinese drugs " published referring to Cao Chunlin chief editor's Shanghai science tech publishing house.
The following preparation method preparation of preferred employing:
2, preparation technology:
(1) Rhizoma Corydalis, Radix Angelicae Sinensis add Diluted Alcohol reflux, extract, 2-3 time, and 2-3 hour for the first time, 1-2 hour for the second time, merge extractive liquid, filtered, and filtrate recycling ethanol is concentrated into relative density and is the clear paste of 1.28～1.30 (80 ℃), and is standby;
(2) Radix Ginseng, the Radix Astragali, Radix Rehmanniae Preparata, the Rhizoma Atractylodis Macrocephalae, Poria, Radix Angelicae Sinensis, Cortex Cinnamomi, the Radix Paeoniae Alba, Radix Glycyrrhizae Preparata, Rhizoma Chuanxiong add water 8-12 and doubly decoct 2-3 time, each 1-2 hour, collecting decoction filtered, filtrate is concentrated into the clear paste that relative density is 1.28～1.30 (80 ℃), and is standby;
(3) step (1) gained clear paste and step (2) gained clear paste are merged, mixing, drying under reduced pressure is pulverized, and sieves, and adds appropriate amount of auxiliary materials and makes different oral formulations.
Effective ingredient of the present invention can be prepared into oral formulations such as granule, capsule, tablet, oral liquid, effervescent tablet, dispersible tablet etc. with acceptable accessories.
The effective ingredient of drug regimen of the present invention has the effect of beneficial heart nourishing the liver hemopoietic, benefiting qi and nourishing blood hair growth promoting, is used for deficiency of qi and blood, the sallow or light white simple and unadorned insomnia of disease meeting color, and dizziness, order is stuck with paste, the limb fiber crops.The women is few through blood volume, the light or unlikely person of delayed period of color.
The specific embodiment of form is described in further detail foregoing of the present invention by the following examples.Following example is based on the above-mentioned subject area of the present invention, but is not limited to following example.
The specific embodiment
Embodiment 1: the preparation of granule
1, prescription:
200 parts of 150 parts of Radix Rehmanniae Preparata of 150 parts of Radixs Astragali of Radix Ginseng
100 parts of 100 parts of Radix Angelicae Sinensis of 150 parts of Poria of the Rhizoma Atractylodis Macrocephalae
150 parts of 100 parts of Radix Glycyrrhizae Preparatas of 100 portions of Radix Paeoniae Albas of Cortex Cinnamomi
100 parts of 80 parts of Rhizoma Corydalis of Rhizoma Chuanxiong
2, preparation technology:
(1) Rhizoma Corydalis, Radix Angelicae Sinensis add Diluted Alcohol reflux, extract, 2-3 time, and 2-3 hour for the first time, 1-2 hour for the second time, merge extractive liquid, filtered, and filtrate recycling ethanol is concentrated into relative density and is the clear paste of 1.28～1.30 (80 ℃), and is standby;
(2) Radix Ginseng, the Radix Astragali, Radix Rehmanniae Preparata, the Rhizoma Atractylodis Macrocephalae, Poria, Cortex Cinnamomi, the Radix Paeoniae Alba, Radix Glycyrrhizae Preparata, Rhizoma Chuanxiong, add water 8-12 and doubly decoct 2-3 time, each 1-2 hour, collecting decoction filtered, filtrate is concentrated into the clear paste that relative density is 1.28～1.30 (80 ℃), and is standby;
(3) step (1) gained clear paste and step (2) gained clear paste are merged, mixing, drying under reduced pressure adds dextrin and pulverizes, and sieves, and makes granule, promptly.
Embodiment 2: the preparation of tablet
1, prescription:
200 parts of 150 parts of Radix Rehmanniae Preparata of 150 parts of Radixs Astragali of Radix Ginseng
100 parts of 100 parts of Radix Angelicae Sinensis of 150 parts of Poria of the Rhizoma Atractylodis Macrocephalae
150 parts of 100 parts of Radix Glycyrrhizae Preparatas of 100 portions of Radix Paeoniae Albas of Cortex Cinnamomi
100 parts of 80 parts of Rhizoma Corydalis of Rhizoma Chuanxiong
2, preparation technology:
(1) Rhizoma Corydalis, Radix Angelicae Sinensis add Diluted Alcohol reflux, extract, 2-3 time, and 2-3 hour for the first time, 1-2 hour for the second time, merge extractive liquid, filtered, and filtrate recycling ethanol is concentrated into relative density and is the clear paste of 1.28～1.30 (80 ℃), and is standby;
(2) Radix Ginseng, the Radix Astragali, Radix Rehmanniae Preparata, the Rhizoma Atractylodis Macrocephalae, Poria, Cortex Cinnamomi, the Radix Paeoniae Alba, Radix Glycyrrhizae Preparata, Rhizoma Chuanxiong, add water 8-12 and doubly decoct 2-3 time, each 1-2 hour, collecting decoction filtered, filtrate is concentrated into the clear paste that relative density is 1.28～1.30 (80 ℃), and is standby;
(3) step (1) gained clear paste and step (2) gained clear paste are merged, mixing, drying under reduced pressure is pulverized the back and is added starch, pelletizing press sheet, promptly.
Embodiment 3: the preparation of capsule
1, prescription:
200 parts of 150 parts of Radix Rehmanniae Preparata of 150 parts of Radixs Astragali of Radix Ginseng
100 parts of 100 parts of Radix Angelicae Sinensis of 150 parts of Poria of the Rhizoma Atractylodis Macrocephalae
150 parts of 100 parts of Radix Glycyrrhizae Preparatas of 100 portions of Radix Paeoniae Albas of Cortex Cinnamomi
100 parts of 80 parts of Rhizoma Corydalis of Rhizoma Chuanxiong
2, preparation technology:
(1) Rhizoma Corydalis, Radix Angelicae Sinensis add Diluted Alcohol reflux, extract, 2-3 time, and 2-3 hour for the first time, 1-2 hour for the second time, merge extractive liquid, filtered, and filtrate recycling ethanol is concentrated into relative density and is the clear paste of 1.28～1.30 (80 ℃), and is standby;
(2) Radix Ginseng, the Radix Astragali, Radix Rehmanniae Preparata, the Rhizoma Atractylodis Macrocephalae, Poria, Cortex Cinnamomi, the Radix Paeoniae Alba, Radix Glycyrrhizae Preparata, Rhizoma Chuanxiong, add water 8-12 and doubly decoct 2-3 time, each 1-2 hour, collecting decoction filtered, filtrate is concentrated into the clear paste that relative density is 1.28～1.30 (80 ℃), and is standby;
(3) step (1) gained clear paste and step (2) gained clear paste are merged, mixing, drying under reduced pressure is pulverized the back and is added starch, makes granule, incapsulates, promptly.
Claims (5)
1, a kind of Chinese medicine composition for the treatment of female anemia is characterized in that being made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made by following raw materials according:
Radix Ginseng 150-300 part Radix Astragali 150-300 part Radix Rehmanniae Preparata 150-300 part
Rhizoma Atractylodis Macrocephalae 100-300 part Poria 100-200 part Radix Angelicae Sinensis 100-200 part
Cortex Cinnamomi 100-200 part Radix Paeoniae Alba 100-200 part Radix Glycyrrhizae Preparata 100-300 part
Rhizoma Chuanxiong 50-100 part Rhizoma Corydalis 100-200 part
2, a kind of Chinese medicine composition for the treatment of female anemia according to claim 1 is characterized in that wherein preparing the preferred following raw materials according of described active ingredient:
200 parts of 150 parts of Radix Rehmanniae Preparata of 150 parts of Radixs Astragali of Radix Ginseng
100 parts of 100 parts of Radix Angelicae Sinensis of 150 parts of Poria of the Rhizoma Atractylodis Macrocephalae
150 parts of 100 parts of Radix Glycyrrhizae Preparatas of 100 portions of Radix Paeoniae Albas of Cortex Cinnamomi
100 parts of 80 parts of Rhizoma Corydalis of Rhizoma Chuanxiong
3, according to the described a kind of Chinese medicine composition for the treatment of female anemia of claim 1-2, it is characterized in that adopting following method to make:
(1) Rhizoma Corydalis, Radix Angelicae Sinensis add Diluted Alcohol reflux, extract, 2-3 time, and 2-3 hour for the first time, 1-2 hour for the second time, merge extractive liquid, filtered, and filtrate recycling ethanol is concentrated into relative density and is the clear paste of 1.28～1.30 (80 ℃), and is standby;
(2) Radix Ginseng, the Radix Astragali, Radix Rehmanniae Preparata, the Rhizoma Atractylodis Macrocephalae, Poria, Cortex Cinnamomi, the Radix Paeoniae Alba, Radix Glycyrrhizae Preparata, Rhizoma Chuanxiong, add water 8-12 and doubly decoct 2-3 time, each 1-2 hour, collecting decoction filtered, filtrate is concentrated into the clear paste that relative density is 1.28～1.30 (80 ℃), and is standby;
(3) step (1) gained clear paste and step (2) gained clear paste are merged, mixing, drying under reduced pressure is pulverized, and sieves, and adds appropriate amount of auxiliary materials and makes different oral formulations.
4, according to any one described a kind of Chinese medicine composition for the treatment of female anemia among the claim 1-3, it is characterized in that this Chinese medicine composition is an oral formulations.
5, according to the described a kind of Chinese medicine composition for the treatment of female anemia of claim 3-4, it is characterized in that this Chinese medicine composition can be made into granule, capsule, tablet.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN200810101474A CN101524437A (en) | 2008-03-07 | 2008-03-07 | Chinese medicinal composition for treating female anemia and preparation method thereof |
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| CN200810101474A CN101524437A (en) | 2008-03-07 | 2008-03-07 | Chinese medicinal composition for treating female anemia and preparation method thereof |
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| CN101524437A true CN101524437A (en) | 2009-09-09 |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103330832A (en) * | 2013-05-29 | 2013-10-02 | 陈松 | Chinese medicine for curing anaemia |
| CN103497871A (en) * | 2012-03-29 | 2014-01-08 | 海丝克（河南）生物科技有限公司 | Formulation method for blood-nourishing yin-nourishing health-care wine |
| CN103550508A (en) * | 2013-10-31 | 2014-02-05 | 钱丹丹 | Traditional Chinese medicine for treating anemia |
| CN103585515A (en) * | 2013-10-23 | 2014-02-19 | 青岛华仁技术孵化器有限公司 | Effervescing agent medicament for treating children alimentary anemia |
| CN107929421A (en) * | 2018-01-03 | 2018-04-20 | 郑州紫德堂生物科技有限公司 | One kind is promoted blood circulation with qi and blood health-care powder and preparation method thereof |
| CN111329924A (en) * | 2020-05-07 | 2020-06-26 | 陕西郝其军制药股份有限公司 | Eight-treasure marrow-supplementing hematogenesis capsule traditional Chinese medicine composition and preparation method thereof |
| CN113952391A (en) * | 2021-11-18 | 2022-01-21 | 广州医科大学 | A Chinese medicinal composition and its preparation method |
-
2008
- 2008-03-07 CN CN200810101474A patent/CN101524437A/en active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103497871A (en) * | 2012-03-29 | 2014-01-08 | 海丝克（河南）生物科技有限公司 | Formulation method for blood-nourishing yin-nourishing health-care wine |
| CN103330832A (en) * | 2013-05-29 | 2013-10-02 | 陈松 | Chinese medicine for curing anaemia |
| CN103585515A (en) * | 2013-10-23 | 2014-02-19 | 青岛华仁技术孵化器有限公司 | Effervescing agent medicament for treating children alimentary anemia |
| CN103550508A (en) * | 2013-10-31 | 2014-02-05 | 钱丹丹 | Traditional Chinese medicine for treating anemia |
| CN107929421A (en) * | 2018-01-03 | 2018-04-20 | 郑州紫德堂生物科技有限公司 | One kind is promoted blood circulation with qi and blood health-care powder and preparation method thereof |
| CN111329924A (en) * | 2020-05-07 | 2020-06-26 | 陕西郝其军制药股份有限公司 | Eight-treasure marrow-supplementing hematogenesis capsule traditional Chinese medicine composition and preparation method thereof |
| CN113952391A (en) * | 2021-11-18 | 2022-01-21 | 广州医科大学 | A Chinese medicinal composition and its preparation method |
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Open date: 20090909 |