CN101279070A - Medicament composite for warming kidney and promoting blood circulation, and dredging channels and collaterals, and method of preparing the same - Google Patents
Medicament composite for warming kidney and promoting blood circulation, and dredging channels and collaterals, and method of preparing the same Download PDFInfo
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Abstract
The invention discloses a medicine combination with the functions of warming the kidney, activating blood, promoting blood circulation and removing stasis; the active components of medicine combination are extracted from more than ten medicinal materials such as mulberry seed, fructus corni, white peony root, semen amomi amari, semen cassiae torae, safflower, szechwan lovage rhizome, olibanum, commiphora myrrha, rhizoma corydalis, myrobalan, prepared kusnezoff monkshood root, rhizoma acori graminei, common aucklandia root, agalloch, szechwan chinaberry fruit, etc. The unique active components of the medical combination of the invention has the functions of warming the kidney and activating blood, promoting the production of body fluid to moisten the intestines, dispelling wind and cold and clearing meridians and collaterals and good curative effects on sciatica, rheumatism, rheumatoid arthritis, arthrodynia, scapulohumeral periarthritis, lumbar muscle strain, cervical spondylosis and lumbar intervertebral disc herniation.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine pharmacy, be specifically related to drug regimen of a kind of warming kidney and promoting blood circulation, dredge the meridian passage and preparation method thereof.
Technical background
Sciatica is meant the radiated pain in sciatic nerve path and areal area thereof.Be a kind of symptom that multiple disease causes, be divided into root, dryness sciatica.Be divided into root and dryness two classes by the disease damage.Pilosity is born in one-sided, sees with male person between twenty and fifty more.Sciatica, cause of disease complexity is various, and can show effect repeatedly.Modern western medicine is mainly based on symptomatic treatment, and effect is still undesirable.
Occuping the first in the various in vivo neuralgias of sciatica, is commonly encountered diseases.But sciatica is a symptom of disease, and itself is not an independently disease.Age of onset was everlasting 20～60 years old, wherein saw at most about 40 years old.Rare later on before 20 years old with 60 years old.Sciatica is meant the pain of sciatic nerve path and areal area thereof.That is to say that the pain in the outside and lateral border of foot all is referred to as sciatica behind buttocks that any reason causes, thigh rear side, the shank.
Mongolian medicine's theory is thought: sciatica be because of wear very little clothes for a long time, have a cold after the diaphoresis, the rainy day is moist or in the cold snap entry etc., causes that wind and cold is wet to make a bet, buttocks and thigh are sent out and are heavyly sent out stiffly, make neural blood vessel passages through which vital energy circulates functional disorder, cause sciatica.The principle of mongolian medicine treatment sciatica is that warming kidney and promoting blood circulation drives the systemic blood circulation, dredge the meridian passage, relaxed muscle nerve, promotion organism metabolism.
The present invention is the basis according to Mongolian medicine's theory, form in conjunction with clinical experience prescription for many years, in the side Fructus Mori, Fructus Corni, the Radix Paeoniae Alba, Fructus Alpiniae Oxyphyllae have warming kidney and promoting blood circulation, the effect of the intestine moistening of promoting the production of body fluid, Rhizoma Chuanxiong, Olibanum, Myrrha, Rhizoma Corydalis have the effect of expelling wind and cold, dredge the meridian passage, all medicines close and use it, have warming kidney and promoting blood circulation, an effect of the intestine moistening of promoting the production of body fluid, expelling wind and cold, dredge the meridian passage.
Summary of the invention:
One of purpose of the present invention provides the drug regimen of a kind of warming kidney and promoting blood circulation, dredge the meridian passage.
Another object of the present invention provides the preparation method of this drug regimen.
Chinese medicine of the present invention is made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made (part is unit of weight) by following raw materials according:
1. write out a prescription:
Fructus Mori 60-180 part Fructus Corni 60-180 part Radix Paeoniae Alba 120-360 part
Fructus Alpiniae Oxyphyllae 60-180 part Semen Cassiae 60-180 part Flos Carthami 60-180 part
Rhizoma Chuanxiong 120-360 part Olibanum 60-180 part Myrrha 120-360 part
Rhizoma Corydalis 120-360 part Fructus Chebulae 60-180 part Radix Aconiti Kusnezoffii Preparata 60-180 part
Rhizoma Acori Graminei 60-180 part Radix Aucklandiae 60-180 part Lignum Aquilariae Resinatum 60-180 part
Fructus Toosendan 60-180 part
The active component that preferred following raw materials according is made, curative effect is better:
240 parts of 120 portions of Radix Paeoniae Albas of 120 parts of Fructus Corni of Fructus Mori
120 parts on 120 parts of Flos Carthamis of 120 parts of Semen Cassiaes of Fructus Alpiniae Oxyphyllae
240 parts of 120 parts of Myrrhas of 240 parts of Olibanums of Rhizoma Chuanxiong
120 parts of 120 parts of Radix Aconiti Kusnezoffii Preparatas of 240 parts of Fructus Chebulaes of Rhizoma Corydalis
120 parts of 120 portions of Lignum Aquilariae Resinatum of 120 parts of Radix Aucklandiae of Rhizoma Acori Graminei
120 parts of Fructus Toosendans
The active ingredient preparation method of Chinese medicine of the present invention can be that raw material is dry respectively, and levigation mixes.It also can be the conventional method preparation of adopting herbal pharmaceutical.These pharmacy conventional methods can be water extract-alcohol precipitation or ethanol extract from water precipitation, also have other extracting method in addition, specifically " pharmaceutics of Chinese drugs " published referring to Cao Chunlin chief editor's Shanghai science tech publishing house.
The following preparation method preparation of preferred employing:
2. preparation technology
(1) Rhizoma Corydalis adds 75% ethanol warm macerating 30 minutes, the reflux, extract, secondary, and 2.5 hours for the first time, 2 hours for the second time, merge extractive liquid, was concentrated into the thick paste shape;
(2) get Fructus Mori, Fructus Corni, the Radix Paeoniae Alba, Fructus Alpiniae Oxyphyllae, Semen Cassiae, Flos Carthami, Rhizoma Chuanxiong, Olibanum, Myrrha, Fructus Chebulae, Radix Aconiti Kusnezoffii Preparata, Rhizoma Acori Graminei, the Radix Aucklandiae, Lignum Aquilariae Resinatum, Fructus Toosendan and decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, filter, merging filtrate, filtrate are condensed into the clear paste that relative density is 1.08～1.14 (50～60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape;
(3) step (1) gained thick paste is mixed with step (2) gained thick paste, drying is ground into fine powder, adds acceptable accessories and makes different preparations such as granule, sheet, capsule.
Adopt mutual compatibility of above-mentioned raw material of Chinese medicine and preparation method thereof, full side has warming kidney and promoting blood circulation, the effect of the intestine moistening of promoting the production of body fluid, expelling wind and cold, dredge the meridian passage, to sciatica, rheumatism, rheumatoid arthritis, arthralgia, scapulohumeral periarthritis, lumbar muscle strain, cervical spondylosis, the effect of prolapse of lumbar intervertebral disc good curing.
By the following examples technical scheme of the present invention is described further.
Embodiment 1: the preparation method of granule
1. write out a prescription:
240 parts of 120 portions of Radix Paeoniae Albas of 120 parts of Fructus Corni of Fructus Mori
120 parts on 120 parts of Flos Carthamis of 120 parts of Semen Cassiaes of Fructus Alpiniae Oxyphyllae
240 parts of 120 parts of Myrrhas of 240 parts of Olibanums of Rhizoma Chuanxiong
120 parts of 120 parts of Radix Aconiti Kusnezoffii Preparatas of 240 parts of Fructus Chebulaes of Rhizoma Corydalis
120 parts of 120 portions of Lignum Aquilariae Resinatum of 120 parts of Radix Aucklandiae of Rhizoma Acori Graminei
120 parts of Fructus Toosendans
2. preparation technology
(1) Rhizoma Corydalis adds 75% ethanol warm macerating 30 minutes, the reflux, extract, secondary, and 2.5 hours for the first time, 2 hours for the second time, merge extractive liquid, was concentrated into the thick paste shape;
(2) get Fructus Mori, Fructus Corni, the Radix Paeoniae Alba, Fructus Alpiniae Oxyphyllae, Semen Cassiae, Flos Carthami, Rhizoma Chuanxiong, Olibanum, Myrrha, Fructus Chebulae, Radix Aconiti Kusnezoffii Preparata, Rhizoma Acori Graminei, the Radix Aucklandiae, Lignum Aquilariae Resinatum, Fructus Toosendan and decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, filter, merging filtrate, filtrate are condensed into the clear paste that relative density is 1.08～1.14 (50～60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape;
(3) step (1) gained thick paste is mixed with step (2) gained thick paste, drying is ground into fine powder, adds cane sugar powder, and mixing is made granule, drying, promptly.
Embodiment 2: the preparation method of tablet
1. write out a prescription:
240 parts of 120 portions of Radix Paeoniae Albas of 120 parts of Fructus Corni of Fructus Mori
120 parts on 120 parts of Flos Carthamis of 120 parts of Semen Cassiaes of Fructus Alpiniae Oxyphyllae
240 parts of 120 parts of Myrrhas of 240 parts of Olibanums of Rhizoma Chuanxiong
120 parts of 120 parts of Radix Aconiti Kusnezoffii Preparatas of 240 parts of Fructus Chebulaes of Rhizoma Corydalis
120 parts of 120 portions of Lignum Aquilariae Resinatum of 120 parts of Radix Aucklandiae of Rhizoma Acori Graminei
120 parts of Fructus Toosendans
2. preparation technology
(1) Rhizoma Corydalis adds 75% ethanol warm macerating 30 minutes, the reflux, extract, secondary, and 2.5 hours for the first time, 2 hours for the second time, merge extractive liquid, was concentrated into the thick paste shape;
(2) get Fructus Mori, Fructus Corni, the Radix Paeoniae Alba, Fructus Alpiniae Oxyphyllae, Semen Cassiae, Flos Carthami, Rhizoma Chuanxiong, Olibanum, Myrrha, Fructus Chebulae, Radix Aconiti Kusnezoffii Preparata, Rhizoma Acori Graminei, the Radix Aucklandiae, Lignum Aquilariae Resinatum, Fructus Toosendan and decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, filter, merging filtrate, filtrate are condensed into the clear paste that relative density is 1.08～1.14 (50～60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape;
(3) step (1) gained thick paste is mixed with step (2) gained thick paste, drying is ground into fine powder, adds starch, magnesium stearate, tabletting, promptly.
Embodiment 3: the preparation method of capsule
1. write out a prescription:
240 parts of 120 portions of Radix Paeoniae Albas of 120 parts of Fructus Corni of Fructus Mori
120 parts on 120 parts of Flos Carthamis of 120 parts of Semen Cassiaes of Fructus Alpiniae Oxyphyllae
240 parts of 120 parts of Myrrhas of 240 parts of Olibanums of Rhizoma Chuanxiong
120 parts of 120 parts of Radix Aconiti Kusnezoffii Preparatas of 240 parts of Fructus Chebulaes of Rhizoma Corydalis
120 parts of 120 portions of Lignum Aquilariae Resinatum of 120 parts of Radix Aucklandiae of Rhizoma Acori Graminei
120 parts of Fructus Toosendans
2. preparation technology
(1) Rhizoma Corydalis adds 75% ethanol warm macerating 30 minutes, the reflux, extract, secondary, and 2.5 hours for the first time, 2 hours for the second time, merge extractive liquid, was concentrated into the thick paste shape;
(2) get Fructus Mori, Fructus Corni, the Radix Paeoniae Alba, Fructus Alpiniae Oxyphyllae, Semen Cassiae, Flos Carthami, Rhizoma Chuanxiong, Olibanum, Myrrha, Fructus Chebulae, Radix Aconiti Kusnezoffii Preparata, Rhizoma Acori Graminei, the Radix Aucklandiae, Lignum Aquilariae Resinatum, Fructus Toosendan and decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, filter, merging filtrate, filtrate are condensed into the clear paste that relative density is 1.08～1.14 (50～60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape;
(3) step (1) gained thick paste is mixed with step (2) gained thick paste, drying is ground into fine powder, sieves, and adds starch, and mixing is made granule, and drying incapsulates, promptly.
Claims (5)
1, the drug regimen of a kind of warming kidney and promoting blood circulation, dredge the meridian passage is characterized in that being made up of active ingredient and/or pharmaceutically acceptable carrier, and wherein said active ingredient is made by following raw materials according:
Fructus Mori 60-180 part Fructus Corni 60-180 part Radix Paeoniae Alba 120-360 part
Fructus Alpiniae Oxyphyllae 60-180 part Semen Cassiae 60-180 part Flos Carthami 60-180 part
Rhizoma Chuanxiong 120-360 part Olibanum 60-180 part Myrrha 120-360 part
Rhizoma Corydalis 120-360 part Fructus Chebulae 60-180 part Radix Aconiti Kusnezoffii Preparata 60-180 part
Rhizoma Acori Graminei 60-180 part Radix Aucklandiae 60-180 part Lignum Aquilariae Resinatum 60-180 part
Fructus Toosendan 60-180 part.
2, the drug regimen of a kind of warming kidney and promoting blood circulation according to claim 1, dredge the meridian passage is characterized in that wherein preparing the preferred following raw materials according of described active ingredient:
240 parts of 120 portions of Radix Paeoniae Albas of 120 parts of Fructus Corni of Fructus Mori
120 parts on 120 parts of Flos Carthamis of 120 parts of Semen Cassiaes of Fructus Alpiniae Oxyphyllae
240 parts of 120 parts of Myrrhas of 240 parts of Olibanums of Rhizoma Chuanxiong
120 parts of 120 parts of Radix Aconiti Kusnezoffii Preparatas of 240 parts of Fructus Chebulaes of Rhizoma Corydalis
120 parts of 120 portions of Lignum Aquilariae Resinatum of 120 parts of Radix Aucklandiae of Rhizoma Acori Graminei
120 parts of Fructus Toosendans.
3, according to the drug regimen of the described a kind of warming kidney and promoting blood circulation of claim 1-2, dredge the meridian passage, it is characterized in that adopting following method to make:
(1) Rhizoma Corydalis adds 75% ethanol warm macerating 30 minutes, the reflux, extract, secondary, and 2.5 hours for the first time, 2 hours for the second time, merge extractive liquid, was concentrated into the thick paste shape;
(2) get Fructus Mori, Fructus Corni, the Radix Paeoniae Alba, Fructus Alpiniae Oxyphyllae, Semen Cassiae, Flos Carthami, Rhizoma Chuanxiong, Olibanum, Myrrha, Fructus Chebulae, Radix Aconiti Kusnezoffii Preparata, Rhizoma Acori Graminei, the Radix Aucklandiae, Lignum Aquilariae Resinatum, Fructus Toosendan and decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, filter, merging filtrate, filtrate are condensed into the clear paste that relative density is 1.08～1.14 (50～60 ℃), add 2.8 times of amount ethanol, stir evenly, be heated to 60 ℃, left standstill 24 hours, filter, decompression filtrate recycling ethanol is condensed into the thick paste shape;
(3) step (1) gained thick paste is mixed with step (2) gained thick paste, drying is ground into fine powder, adds acceptable accessories and makes different preparations such as granule, sheet, capsule.
4,, it is characterized in that this Chinese medicine composition is an oral formulations according to the drug regimen of any one described a kind of warming kidney and promoting blood circulation, dredge the meridian passage among the claim 1-3.
5,, it is characterized in that this Chinese medicine composition can be made into granule, capsule, tablet according to the drug regimen of the described a kind of warming kidney and promoting blood circulation of claim 3-4, dredge the meridian passage.
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| CNA2008101037703A CN101279070A (en) | 2008-04-10 | 2008-04-10 | Medicament composite for warming kidney and promoting blood circulation, and dredging channels and collaterals, and method of preparing the same |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105477115A (en) * | 2016-01-14 | 2016-04-13 | 徐州医学院附属医院 | Traditional Chinese medicine ointment for treating frozen shoulder as well as preparation method and application of traditional Chinese medicine ointment |
| CN106074660A (en) * | 2016-08-11 | 2016-11-09 | 南京中医药大学 | Olibanum and Myrrha application in preparation preventing and treating neuropathic pain disease medicament |
| CN109846861A (en) * | 2019-03-14 | 2019-06-07 | 内蒙古科尔沁药业有限公司 | A kind of anaesthetic external plaster and preparation method thereof |
-
2008
- 2008-04-10 CN CNA2008101037703A patent/CN101279070A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105477115A (en) * | 2016-01-14 | 2016-04-13 | 徐州医学院附属医院 | Traditional Chinese medicine ointment for treating frozen shoulder as well as preparation method and application of traditional Chinese medicine ointment |
| CN106074660A (en) * | 2016-08-11 | 2016-11-09 | 南京中医药大学 | Olibanum and Myrrha application in preparation preventing and treating neuropathic pain disease medicament |
| CN109846861A (en) * | 2019-03-14 | 2019-06-07 | 内蒙古科尔沁药业有限公司 | A kind of anaesthetic external plaster and preparation method thereof |
| CN109846861B (en) * | 2019-03-14 | 2022-06-24 | 内蒙古科尔沁药业有限公司 | Externally applied Mongolian medicine plaster and preparation method thereof |
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Open date: 20081008 |