CN115551894A - 新型抗lilrb4抗体和衍生产物 - Google Patents

新型抗lilrb4抗体和衍生产物 Download PDF

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Publication number
CN115551894A
CN115551894A CN202180034809.4A CN202180034809A CN115551894A CN 115551894 A CN115551894 A CN 115551894A CN 202180034809 A CN202180034809 A CN 202180034809A CN 115551894 A CN115551894 A CN 115551894A
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antibody
antigen
domain
cancer
cell
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Chinese (zh)
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宋安
黄涛
R·斯塔夫德
M·J·科斯塔
K·H·洪
C·博南斯
周建辉
周立
李冀
J·P·伍达德
廖晓伶
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Yiming Biological Immune Medical Co
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Yiming Biological Immune Medical Co
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CN202180034809.4A 2020-03-12 2021-03-12 新型抗lilrb4抗体和衍生产物 Pending CN115551894A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202062988892P 2020-03-12 2020-03-12
US62/988,892 2020-03-12
PCT/US2021/022029 WO2021183839A2 (en) 2020-03-12 2021-03-12 Novel anti-lilrb4 antibodies and derivative products

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CN115551894A true CN115551894A (zh) 2022-12-30

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US (1) US12559555B2 (https=)
EP (1) EP4118120A4 (https=)
JP (2) JP7765397B2 (https=)
KR (1) KR20220152316A (https=)
CN (1) CN115551894A (https=)
AU (1) AU2021236302A1 (https=)
BR (1) BR112022018088A2 (https=)
CA (1) CA3175140A1 (https=)
WO (1) WO2021183839A2 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024235317A1 (zh) 2023-05-18 2024-11-21 南京维立志博生物科技有限公司 结合lilrb4和cd3的抗体及其用途
WO2024251242A1 (en) * 2023-06-09 2024-12-12 Antengene (Hangzhou) Biologics Co., Ltd. Novel antibodies targeting cd3 and another target and uses thereof
WO2024255756A1 (zh) * 2023-06-13 2024-12-19 南京维立志博生物科技股份有限公司 基于共同轻链产生双特异性抗体的方法
CN119985985A (zh) * 2025-04-16 2025-05-13 南昌大学第一附属医院 急性髓系白血病易感或预后不良人群的筛选试剂盒

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WO2020232247A1 (en) 2019-05-14 2020-11-19 Provention Bio, Inc. Methods and compositions for preventing type 1 diabetes
IL298999A (en) 2020-06-11 2023-02-01 Provention Bio Inc Methods and compositions for the prevention of type 1 diabetes
JP2024520444A (ja) 2021-05-24 2024-05-24 プロヴェンション・バイオ・インコーポレイテッド １型糖尿病を治療するための方法
WO2023159152A2 (en) * 2022-02-17 2023-08-24 Immune-Onc Therapeutics, Inc. Combination therapy of lilrb antagonist and pd-1/pd-l1 axis inhibitor
EP4499683A1 (en) 2022-03-29 2025-02-05 NGM Biopharmaceuticals, Inc. Ilt3 and cd3 binding agents and methods of use thereof
AU2023258644A1 (en) * 2022-04-25 2024-12-05 Biond Biologics Ltd. Anti-ilt3 antibodies and use thereof
WO2023235699A1 (en) * 2022-05-31 2023-12-07 Jounce Therapeutics, Inc. Antibodies to lilrb4 and uses thereof
WO2023236891A1 (en) * 2022-06-06 2023-12-14 Antengene (Hangzhou) Biologics Co., Ltd. Novel anti-lilrb4 antibodies and uses thereof
CN114716554B (zh) * 2022-06-08 2022-08-26 尚健单抗（北京）生物技术有限公司 抗原结合蛋白及其应用
CN115925941B (zh) * 2022-06-08 2026-04-03 北京科诺信诚科技有限公司 靶向人lilrb4的纳米抗体及其应用
CN117362433A (zh) * 2022-06-30 2024-01-09 杭州尚健生物技术有限公司 分离的抗原结合蛋白及其用途
EP4606823A1 (en) * 2022-12-26 2025-08-27 Bristar Immunotech Limited Synthetic t cell receptor antigen receptor specifically binding to lilrb4 and use thereof
CN115873119B (zh) * 2022-12-30 2026-01-23 北京东方百泰生物科技股份有限公司 一种抗lilrb4单克隆抗体的纯化方法
EP4694900A1 (en) * 2023-04-13 2026-02-18 The Johns Hopkins University Engineered t-cell receptors and methods of making and using the same
CN118580352A (zh) * 2023-05-20 2024-09-03 四川大学 抗lilrb4抗体及其用途
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