CN1155417A - S(+)-布洛芬的口服制剂 - Google Patents

S(+)-布洛芬的口服制剂 Download PDF

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Publication number
CN1155417A
CN1155417A CN96112209A CN96112209A CN1155417A CN 1155417 A CN1155417 A CN 1155417A CN 96112209 A CN96112209 A CN 96112209A CN 96112209 A CN96112209 A CN 96112209A CN 1155417 A CN1155417 A CN 1155417A
Authority
CN
China
Prior art keywords
acid
ibuprofen
eutomer
composition
drug compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN96112209A
Other languages
English (en)
Chinese (zh)
Inventor
L·G·亨伯
G·L·路特
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to TW085104431A priority Critical patent/TW442287B/zh
Priority to US08/661,207 priority patent/US5780046A/en
Priority to ZA9604929A priority patent/ZA964929B/xx
Priority to IN1076CA1996 priority patent/IN182039B/en
Priority to CA002178691A priority patent/CA2178691A1/en
Priority to SK744-96A priority patent/SK74496A3/sk
Priority to EA199600028A priority patent/EA000046B1/ru
Priority to NZ286790A priority patent/NZ286790A/en
Priority to CZ961703A priority patent/CZ170396A3/cs
Priority to AU55881/96A priority patent/AU715367B2/en
Priority to PL96314731A priority patent/PL314731A1/xx
Priority to EP96304322A priority patent/EP0753296A3/en
Application filed by American Home Products Corp filed Critical American Home Products Corp
Priority to NO962490A priority patent/NO962490L/no
Priority to EE9600068A priority patent/EE9600068A/xx
Priority to BR9602759A priority patent/BR9602759A/pt
Priority to IL11863796A priority patent/IL118637A/xx
Priority to HU9601619A priority patent/HUP9601619A3/hu
Priority to TR96/00498A priority patent/TR199600498A2/xx
Priority to JP8150867A priority patent/JPH092949A/ja
Priority to ARP960103121A priority patent/AR002442A1/es
Priority to CN96112209A priority patent/CN1155417A/zh
Priority to MA24281A priority patent/MA23908A1/fr
Publication of CN1155417A publication Critical patent/CN1155417A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CN96112209A 1995-06-13 1996-06-12 S(+)-布洛芬的口服制剂 Pending CN1155417A (zh)

Priority Applications (22)

Application Number Priority Date Filing Date Title
TW085104431A TW442287B (en) 1995-06-13 1996-04-13 Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac)
ZA9604929A ZA964929B (en) 1995-06-13 1996-06-10 Oral formulations of S(+)-ibuprofen.
IN1076CA1996 IN182039B (enExample) 1995-06-13 1996-06-10
CA002178691A CA2178691A1 (en) 1995-06-13 1996-06-10 Oral formulations of s(+)-ibuprofen
SK744-96A SK74496A3 (en) 1995-06-13 1996-06-10 Organoleptically acceptable oral pharmaceutical compositions
US08/661,207 US5780046A (en) 1995-06-13 1996-06-10 Oral formulations of S(+)-ibuprofen
NZ286790A NZ286790A (en) 1995-06-13 1996-06-11 Organoleptic formulation of s(+)-ibuprofen (isobutylphenyl propionic acid)
CZ961703A CZ170396A3 (en) 1995-06-13 1996-06-11 Organoleptic acceptable pharmaceutical preparation
AU55881/96A AU715367B2 (en) 1995-06-13 1996-06-11 Oral formulations of S(+)-ibuprofen
PL96314731A PL314731A1 (en) 1995-06-13 1996-06-11 S(+)-ibuprofen preparations for oral administration
EP96304322A EP0753296A3 (en) 1995-06-13 1996-06-11 Oral formulations containing S (+) - ibuprofen
EA199600028A EA000046B1 (ru) 1995-06-13 1996-06-11 Оральная композиция, содержащая s(+)-ибупрофен, и способ ее получения
NO962490A NO962490L (no) 1995-06-13 1996-06-12 Orale formuleringer av S(+)-ibuprofen
EE9600068A EE9600068A (et) 1995-06-13 1996-06-12 S(+)-ibuprofeeni suu kaudu manustatavad ravimvormid
BR9602759A BR9602759A (pt) 1995-06-13 1996-06-12 Composição farmacêutica oral organoleticamente aceitável
IL11863796A IL118637A (en) 1995-06-13 1996-06-12 Oral pharmaceutical compositions of s(+)-ibuprofen
HU9601619A HUP9601619A3 (en) 1995-06-13 1996-06-12 Oral formulations of s(+)-ibuprofen and process for preparing them
TR96/00498A TR199600498A2 (tr) 1995-06-13 1996-06-12 S(+)-ibuprofen'in oral formülasyonlari.
JP8150867A JPH092949A (ja) 1995-06-13 1996-06-12 Ｓ（＋）−イブプロフェンの経口製剤
ARP960103121A AR002442A1 (es) 1995-06-13 1996-06-12 Formulaciones orales de ibuprofeno s (+)
CN96112209A CN1155417A (zh) 1995-06-13 1996-06-12 S(+)-布洛芬的口服制剂
MA24281A MA23908A1 (fr) 1995-06-13 1996-06-12 procede de fabrication des s(+) - ibuprofen administrable par voie orale

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16995P 1995-06-13 1995-06-13
US000,169 1995-06-13
CN96112209A CN1155417A (zh) 1995-06-13 1996-06-12 S(+)-布洛芬的口服制剂

Publications (1)

Publication Number Publication Date
CN1155417A true CN1155417A (zh) 1997-07-30

Family

ID=37709653

Family Applications (1)

Application Number Title Priority Date Filing Date
CN96112209A Pending CN1155417A (zh) 1995-06-13 1996-06-12 S(+)-布洛芬的口服制剂

Country Status (22)

Country Link
US (1) US5780046A (enExample)
EP (1) EP0753296A3 (enExample)
JP (1) JPH092949A (enExample)
CN (1) CN1155417A (enExample)
AR (1) AR002442A1 (enExample)
AU (1) AU715367B2 (enExample)
BR (1) BR9602759A (enExample)
CA (1) CA2178691A1 (enExample)
CZ (1) CZ170396A3 (enExample)
EA (1) EA000046B1 (enExample)
EE (1) EE9600068A (enExample)
HU (1) HUP9601619A3 (enExample)
IL (1) IL118637A (enExample)
IN (1) IN182039B (enExample)
MA (1) MA23908A1 (enExample)
NO (1) NO962490L (enExample)
NZ (1) NZ286790A (enExample)
PL (1) PL314731A1 (enExample)
SK (1) SK74496A3 (enExample)
TR (1) TR199600498A2 (enExample)
TW (1) TW442287B (enExample)
ZA (1) ZA964929B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101077343B (zh) * 2006-12-12 2010-06-30 蚌埠丰原涂山制药有限公司 右旋布洛芬颗粒及制备方法
CN102258490A (zh) * 2011-07-01 2011-11-30 中美天津史克制药有限公司 布洛芬咀嚼片

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9625589D0 (en) * 1996-12-10 1997-01-29 Boots Co Plc Therapeutic agents
DE69836207T2 (de) 1997-03-28 2007-08-30 Eisai Co., Ltd. Orale pharmazeutische zusammensetzungen mit reduzierter bitterkeit durch geschmacksmaskiermittel
GB9710521D0 (en) * 1997-05-22 1997-07-16 Boots Co Plc Process
AU7700198A (en) * 1997-06-24 1999-01-04 Fuisz Technologies Ltd. Positive hydration method of preparing confectionery and product therefrom
US6482465B1 (en) 1997-06-24 2002-11-19 Biovail Technologies Ltd. Positive hydration method of preparing confectionery and product therefrom
US6673380B2 (en) 1998-11-17 2004-01-06 Mcneil-Ppc, Inc. Fortified confectionery delivery systems and methods of preparation thereof
AU2006202991B2 (en) * 1998-01-02 2009-01-08 Mcneil-Ppc, Inc. Ibuprofen composition
NZ333474A (en) * 1998-01-02 1999-06-29 Mcneil Ppc Inc A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat
IT1301966B1 (it) 1998-07-30 2000-07-20 Zambon Spa Composizioni farmaceutiche ad attivita' analgesica
US7163705B2 (en) 1998-12-15 2007-01-16 Wm. Wrigley Jr. Company Coated chewing gum product and method of making
WO2001021178A2 (en) * 1999-09-22 2001-03-29 Akzo Nobel, N.V. Method of treating cognitive dysfunction syndrome in dogs and chewable tablet for dogs
US6541025B1 (en) * 1999-12-30 2003-04-01 Shear/Kershman Laboratories, Inc. Method for preparing solid delivery system for encapsulated and non-encapsulated pharmaceuticals
EP1260215B1 (en) * 2000-03-01 2009-07-29 Eisai R&D Management Co., Ltd. Rapidly disintegrable tablet containing polyvinyl alcohol
US6514537B1 (en) 2000-06-02 2003-02-04 Cumberland Swan Holdings, Inc. Magnesium citrate solution
PE20020102A1 (es) * 2000-06-30 2002-03-06 Procter & Gamble Composicion topica oral que comprende un agente modulador de la respuesta del huesped frente a patogenos periodontales
US8283135B2 (en) * 2000-06-30 2012-10-09 The Procter & Gamble Company Oral care compositions containing combinations of anti-bacterial and host-response modulating agents
DK1372669T3 (da) * 2001-01-23 2005-10-17 Gador Sa Bisphosphonatholding sammensætning til forebyggelse og/eller behandling af metaboliske knoglesygdomme, fremgangsmåde til fremstilling af sådanne sammensætninger og anvendelse deraf
IL143318A0 (en) * 2001-05-23 2002-04-21 Herbal Synthesis Corp Herbal compositions for the treatment of mucosal lesions
GB0113843D0 (en) 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
US6866862B2 (en) * 2001-10-05 2005-03-15 Rubicon Scientific Animal feeds including heartworm-prevention drugs
US6716448B2 (en) 2001-10-05 2004-04-06 Rubicon Scientific Llc Domesticated household pet food including maintenance amounts of ivermectin
US7052712B2 (en) * 2001-10-05 2006-05-30 Rubicon Scientific Llc Animal feeds including actives and methods of preparing same
US6551615B1 (en) 2001-10-18 2003-04-22 M/S. Strides Arcolab Limited Dexibuprofen-containing soft gelatin capsules and process for preparing the same
US20040091579A1 (en) * 2002-11-13 2004-05-13 Rubicon Scientific Llc; Extruded foodstuffs having maintenance level actives
IL153124A (en) * 2002-11-27 2010-06-30 Herbal Synthesis Corp Solid composition that can be glued to the lining
US20050069590A1 (en) * 2003-09-30 2005-03-31 Buehler Gail K. Stable suspensions for medicinal dosages
WO2005105102A1 (en) * 2004-05-04 2005-11-10 Equitech Corporation Improved nsaid composition
JP2012046540A (ja) * 2004-05-07 2012-03-08 Daiichi Sankyo Healthcare Co Ltd イブプロフェン含有医薬組成物
AU2005285040A1 (en) * 2004-09-14 2006-03-23 Molecular Therapeutics, Inc. D-methionine formulation with improved biopharmaceutical properties
BRPI0618273A2 (pt) * 2005-11-02 2011-08-23 Teikoku Pharma Usa Inc formulações de dosagem oral de ibuprofeno organolepticamente aceitáveis, métodos de produção e uso das mesmas
US20070232638A1 (en) * 2006-04-03 2007-10-04 Howard Brooks-Korn Opiopathies
BRPI0809430A2 (pt) * 2007-07-23 2014-09-09 Teikoku Pharma Usa Inc Formulações de dosagem oral, organolepticamente aceitáveis, de um agonista indol do receptor de cerotonina e métodos de utilização das mesmas
US8445545B2 (en) * 2008-05-07 2013-05-21 Nicholas DeSica Pharmaceutical composition, method of preparation and methods of treating aches/pains
WO2010132286A1 (en) * 2009-05-12 2010-11-18 Wyeth Llc Orally administered tablet formulation of an antianxiolytic compound
MX2011012078A (es) * 2009-05-20 2012-03-14 Lingual Consegna Pty Ltd Formulacion terapeutica bucal y/o sublingual.
US9636284B2 (en) * 2010-03-31 2017-05-02 Johnson & Johnson Consumer Inc. Oral care compositions
FR2991582B1 (fr) * 2012-06-11 2014-06-13 Isp Investments Inc Extrait de fibres de coton et composition cosmetique et leur utilisation pour proteger, nourrir et hydrater la peau
AU2013318356A1 (en) 2012-09-18 2015-03-19 Mcneil-Ppc, Inc. Low melting propionic acid derivative particles for use in oral dosage forms
BR112015005968A2 (pt) 2012-09-18 2017-07-04 Mcneil Ppc Inc formas de dosagem orais de liberação prolongada compreendendo partículas derivadas do ácido propiônico com baixo ponto de fusão
US20180078516A1 (en) * 2016-09-19 2018-03-22 Innovazone Labs LLC Pharmaceutical Composition of Ibuprofen Sodium for Oral Administration

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2260148A (en) * 1939-06-19 1941-10-21 Frank H Fleer Corp Chewing gum material
GB971700A (en) * 1961-02-02 1964-09-30 Boots Pure Drug Co Ltd Anti-Inflammatory Agents
GB1548022A (en) * 1976-10-06 1979-07-04 Wyeth John & Brother Ltd Pharmaceutial dosage forms
CA1097233A (en) * 1977-07-20 1981-03-10 George K. E. Gregory Packages
US4265847A (en) * 1978-03-30 1981-05-05 Kirby Pharmaceuticals Ltd Tabletting process
US4639368A (en) * 1984-08-23 1987-01-27 Farmacon Research Corporation Chewing gum containing a medicament and taste maskers
DE3440288C2 (de) * 1984-11-05 1987-03-12 Gergely, Gerhard, Dr.-Ing., Wien Pharmazeutische Zubereitung mit einem Gehalt an Ibuprofen sowie Verfahren zu ihrer Herstellung
US4879108A (en) * 1985-12-20 1989-11-07 Warner-Lambert Company Confectionery delivery system for antipyretics
US4764378A (en) * 1986-02-10 1988-08-16 Zetachron, Inc. Buccal drug dosage form
US4873231A (en) * 1986-04-08 1989-10-10 Smith Walton J Decreasing the toxicity of an ibuprofen salt
ATE50493T1 (de) * 1986-11-14 1990-03-15 Puetter Medice Chem Pharm Ibuprofen enthaltendes arzneimittel.
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
US4835186A (en) * 1987-06-15 1989-05-30 American Home Products Corporation Spray dried ibuprofen
US4835187A (en) * 1987-06-15 1989-05-30 American Home Products Corporation Spray dried ibuprofen
US4788220A (en) * 1987-07-08 1988-11-29 American Home Products Corporation (Del.) Pediatric ibuprofen compositions
US4851444A (en) * 1987-07-10 1989-07-25 Analgesic Associates Onset-hastened/enhanced analgesia
US4861797A (en) * 1987-10-15 1989-08-29 Oratech Pharmaceutical Development Corporation Liquid ibuprofen compositions and methods of making them
US4851226A (en) * 1987-11-16 1989-07-25 Mcneil Consumer Products Company Chewable medicament tablet containing means for taste masking
US4835188A (en) * 1987-12-08 1989-05-30 American Home Products Corporation Spray dried ibuprofen
IT1226549B (it) * 1988-07-12 1991-01-24 Resa Farma Composizioni farmaceutiche ad attivita' analgesica ed antiinfiammatoria per uso orale, dotate di ottima palatabilita' ed esenti da effetti irritanti sulle mucose.
DE3838431A1 (de) * 1988-11-12 1990-05-17 Bayer Ag Ibuprofen-brausezubereitungen
US4942039A (en) * 1989-05-09 1990-07-17 Miles Inc. Effervescent analgesic antacid composition having reduced sodium content
US4975465A (en) * 1989-03-28 1990-12-04 American Home Products Corporation Orally administrable ibuprofen compositions
GB8909793D0 (en) * 1989-04-28 1989-06-14 Beecham Group Plc Pharmaceutical formulation
US5100918A (en) * 1989-05-25 1992-03-31 Sterling Drug, Inc. Prevention or treatment of sunburn using the S(+) isomer of ibuprofen
US5084278A (en) * 1989-06-02 1992-01-28 Nortec Development Associates, Inc. Taste-masked pharmaceutical compositions
US5190981A (en) * 1989-08-17 1993-03-02 Sepracor Inc. Formulation containing S(+) enantiomer of flurbiprofen or ketoprofen and method of use for oral administration for prevention and treatment of bone loss associated with periodontal disease
HUT59653A (en) * 1990-11-15 1992-06-29 Puetter Medice Chem Pharm Process for producing complexes containing s/+/-phenyl-alcanoic acids and alpha-hydroxy-alcanoic acids and pharmaceutical compositions containing them as active components
SK279279B6 (sk) * 1991-05-13 1998-09-09 The Boots Company Plc S(-)-nátrium-2-(4-izobutylfenyl)propionát-dihydrát
US5380535A (en) * 1991-05-28 1995-01-10 Geyer; Robert P. Chewable drug-delivery compositions and methods for preparing the same
GB9224021D0 (en) * 1992-11-16 1993-01-06 Boots Co Plc Effervescent compositions
US5332834A (en) * 1992-12-02 1994-07-26 Hoechst Celanese Corporation Racemization of an enantomerically enriched α-aryl carboxylic acid

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101077343B (zh) * 2006-12-12 2010-06-30 蚌埠丰原涂山制药有限公司 右旋布洛芬颗粒及制备方法
CN102258490A (zh) * 2011-07-01 2011-11-30 中美天津史克制药有限公司 布洛芬咀嚼片
CN102258490B (zh) * 2011-07-01 2012-10-03 中美天津史克制药有限公司 布洛芬咀嚼片

Also Published As

Publication number Publication date
AU5588196A (en) 1997-01-02
CA2178691A1 (en) 1996-12-14
HU9601619D0 (en) 1996-08-28
IL118637A (en) 1999-10-28
ZA964929B (en) 1997-12-10
EP0753296A3 (en) 1997-04-23
AU715367B2 (en) 2000-02-03
IN182039B (enExample) 1998-12-12
PL314731A1 (en) 1996-12-23
BR9602759A (pt) 1998-04-22
NO962490L (no) 1996-12-16
AR002442A1 (es) 1998-03-11
NO962490D0 (no) 1996-06-12
SK74496A3 (en) 1997-04-09
IL118637A0 (en) 1996-10-16
HUP9601619A2 (en) 1997-02-28
TR199600498A2 (tr) 1997-03-21
EE9600068A (et) 1996-12-16
EA000046B1 (ru) 1998-04-30
CZ170396A3 (en) 1997-04-16
HUP9601619A3 (en) 1999-05-28
MA23908A1 (fr) 1996-12-31
US5780046A (en) 1998-07-14
EA199600028A2 (ru) 1996-12-30
JPH092949A (ja) 1997-01-07
NZ286790A (en) 1998-02-26
EP0753296A2 (en) 1997-01-15
TW442287B (en) 2001-06-23
EA199600028A3 (ru) 1997-03-31

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