EA199600028A2 - Оральная композиция, содержащая s(+)-ибупрофен, и способ ее получения - Google Patents

Оральная композиция, содержащая s(+)-ибупрофен, и способ ее получения

Info

Publication number
EA199600028A2
EA199600028A2 EA199600028A EA199600028A EA199600028A2 EA 199600028 A2 EA199600028 A2 EA 199600028A2 EA 199600028 A EA199600028 A EA 199600028A EA 199600028 A EA199600028 A EA 199600028A EA 199600028 A2 EA199600028 A2 EA 199600028A2
Authority
EA
Eurasian Patent Office
Prior art keywords
ibuprofen
oral formulations
isobutylphenyl
pharmaceutical composition
propionic acid
Prior art date
Application number
EA199600028A
Other languages
English (en)
Other versions
EA199600028A3 (ru
EA000046B1 (ru
Inventor
Лесли Джордж Хамбер
Джеральд Луис Ройтер
Original Assignee
Американ Хоум Продактс Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Американ Хоум Продактс Корпорейшн filed Critical Американ Хоум Продактс Корпорейшн
Publication of EA199600028A2 publication Critical patent/EA199600028A2/ru
Publication of EA199600028A3 publication Critical patent/EA199600028A3/ru
Publication of EA000046B1 publication Critical patent/EA000046B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Изобретение относится к фармацевтической композиции, используемой в качестве анальгетика для профилактики и лечения людей и животных, и способу ее получения. Сущность изобретения заключается в создании фармацевтической композиции, органолептически пригодной для перорального введения, содержащей кислотный компонент и S(+)-2-(n-изобутилфенил)пропионовую кислоту, практически свободную от R-(-)-2(n-изобутилфенил)пропионовой кислоты. Предложено несколько форм ее выполнения, а именно в виде порошка, гранул, жевательных таблеток и т.п.
EA199600028A 1995-06-13 1996-06-11 Оральная композиция, содержащая s(+)-ибупрофен, и способ ее получения EA000046B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16995P 1995-06-13 1995-06-13
CN96112209A CN1155417A (zh) 1995-06-13 1996-06-12 S(+)-布洛芬的口服制剂

Publications (3)

Publication Number Publication Date
EA199600028A2 true EA199600028A2 (ru) 1996-12-30
EA199600028A3 EA199600028A3 (ru) 1997-03-31
EA000046B1 EA000046B1 (ru) 1998-04-30

Family

ID=37709653

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199600028A EA000046B1 (ru) 1995-06-13 1996-06-11 Оральная композиция, содержащая s(+)-ибупрофен, и способ ее получения

Country Status (22)

Country Link
US (1) US5780046A (ru)
EP (1) EP0753296A3 (ru)
JP (1) JPH092949A (ru)
CN (1) CN1155417A (ru)
AR (1) AR002442A1 (ru)
AU (1) AU715367B2 (ru)
BR (1) BR9602759A (ru)
CA (1) CA2178691A1 (ru)
CZ (1) CZ170396A3 (ru)
EA (1) EA000046B1 (ru)
EE (1) EE9600068A (ru)
HU (1) HUP9601619A3 (ru)
IL (1) IL118637A (ru)
IN (1) IN182039B (ru)
MA (1) MA23908A1 (ru)
NO (1) NO962490L (ru)
NZ (1) NZ286790A (ru)
PL (1) PL314731A1 (ru)
SK (1) SK74496A3 (ru)
TR (1) TR199600498A2 (ru)
TW (1) TW442287B (ru)
ZA (1) ZA964929B (ru)

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KR20080034166A (ko) * 2005-11-02 2008-04-18 테이코쿠 팔마 유에스에이, 인코포레이티드 감각기관 수용성 이부프로펜 경구 투약 제형 및 동일물의제조 및 사용 방법
US20070232638A1 (en) * 2006-04-03 2007-10-04 Howard Brooks-Korn Opiopathies
CN101077343B (zh) * 2006-12-12 2010-06-30 蚌埠丰原涂山制药有限公司 右旋布洛芬颗粒及制备方法
KR20100020449A (ko) * 2007-07-23 2010-02-22 테이코쿠 팔마 유에스에이, 인코포레이티드 기호적으로 허용될 수 있는 인돌 세로토닌 수용체 작용제 경구 투여 제제 및 이를 사용하는 방법
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Also Published As

Publication number Publication date
TR199600498A2 (tr) 1997-03-21
MA23908A1 (fr) 1996-12-31
PL314731A1 (en) 1996-12-23
IL118637A0 (en) 1996-10-16
BR9602759A (pt) 1998-04-22
CN1155417A (zh) 1997-07-30
CA2178691A1 (en) 1996-12-14
HUP9601619A3 (en) 1999-05-28
EE9600068A (et) 1996-12-16
NO962490D0 (no) 1996-06-12
AU715367B2 (en) 2000-02-03
EP0753296A3 (en) 1997-04-23
HU9601619D0 (en) 1996-08-28
EP0753296A2 (en) 1997-01-15
IN182039B (ru) 1998-12-12
TW442287B (en) 2001-06-23
AU5588196A (en) 1997-01-02
CZ170396A3 (en) 1997-04-16
NO962490L (no) 1996-12-16
EA199600028A3 (ru) 1997-03-31
IL118637A (en) 1999-10-28
SK74496A3 (en) 1997-04-09
HUP9601619A2 (en) 1997-02-28
ZA964929B (en) 1997-12-10
US5780046A (en) 1998-07-14
NZ286790A (en) 1998-02-26
EA000046B1 (ru) 1998-04-30
JPH092949A (ja) 1997-01-07
AR002442A1 (es) 1998-03-11

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