CN115322991A - 因子XII、激肽释放酶B、血浆夫列契因子1和激肽原1 iRNA组合物及其使用方法 - Google Patents

因子XII、激肽释放酶B、血浆夫列契因子1和激肽原1 iRNA组合物及其使用方法 Download PDF

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CN115322991A
CN115322991A CN202210790912.8A CN202210790912A CN115322991A CN 115322991 A CN115322991 A CN 115322991A CN 202210790912 A CN202210790912 A CN 202210790912A CN 115322991 A CN115322991 A CN 115322991A
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nucleotides
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dsrna agent
dsrna
agent
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A·阿金克
G·辛克尔
M·迈尔
J·巴特勒
刘璟璇
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Alnylam Pharmaceuticals Inc
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CN202210790912.8A 2015-05-06 2016-05-05 因子XII、激肽释放酶B、血浆夫列契因子1和激肽原1 iRNA组合物及其使用方法 Pending CN115322991A (zh)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201562157890P 2015-05-06 2015-05-06
US62/157,890 2015-05-06
US201562260887P 2015-11-30 2015-11-30
US62/260,887 2015-11-30
US201562266958P 2015-12-14 2015-12-14
US62/266,958 2015-12-14
CN201680039784.6A CN108271386B (zh) 2015-05-06 2016-05-05 因子XII(哈格曼因子)(F12)、激肽释放酶B、血浆(夫列契因子)1(KLKB1)和激肽原1(KNG1)iRNA组合物及其使用方法
PCT/US2016/030876 WO2016179342A2 (en) 2015-05-06 2016-05-05 Factor xii (hageman factor) (f12), kallikrein b, plasma (fletcher factor) 1 (klkb1), and kininogen 1 (kng1) irna compositions and methods of use thereof

Related Parent Applications (1)

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CN201680039784.6A Division CN108271386B (zh) 2015-05-06 2016-05-05 因子XII(哈格曼因子)(F12)、激肽释放酶B、血浆(夫列契因子)1(KLKB1)和激肽原1(KNG1)iRNA组合物及其使用方法

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CN201680039784.6A Active CN108271386B (zh) 2015-05-06 2016-05-05 因子XII(哈格曼因子)(F12)、激肽释放酶B、血浆(夫列契因子)1(KLKB1)和激肽原1(KNG1)iRNA组合物及其使用方法

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US (5) US20180100150A1 (https=)
EP (1) EP3292201A2 (https=)
JP (5) JP6695902B2 (https=)
KR (2) KR102827366B1 (https=)
CN (2) CN115322991A (https=)
AU (4) AU2016257996A1 (https=)
BR (1) BR112017021967A2 (https=)
CA (1) CA2984636A1 (https=)
EA (1) EA201792444A1 (https=)
HK (1) HK1249920A1 (https=)
TW (4) TW202536180A (https=)
UY (2) UY36671A (https=)
WO (1) WO2016179342A2 (https=)

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CN113330117B (zh) * 2019-01-18 2024-05-28 苏州瑞博生物技术股份有限公司 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途
KR20220011689A (ko) 2019-05-22 2022-01-28 쑤저우 리보 라이프 사이언스 컴퍼니, 리미티드 핵산, 약제학적 조성물, 접합체, 제조 방법, 및 용도
US12590304B2 (en) 2019-05-22 2026-03-31 Suzhou Ribo Life Science Co., Ltd. Nucleic acid, pharmaceutical composition, conjugate, preparation method, and use
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CN113795582B (zh) 2019-05-24 2024-05-24 苏州瑞博生物技术股份有限公司 核酸、药物组合物与缀合物及制备方法和用途
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