CN114983905B - Plant repairing composition containing aloe and preparation method and application thereof - Google Patents
Plant repairing composition containing aloe and preparation method and application thereof Download PDFInfo
- Publication number
- CN114983905B CN114983905B CN202210547021.XA CN202210547021A CN114983905B CN 114983905 B CN114983905 B CN 114983905B CN 202210547021 A CN202210547021 A CN 202210547021A CN 114983905 B CN114983905 B CN 114983905B
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- CN
- China
- Prior art keywords
- extract
- aloe vera
- aloe
- kangaroo
- plant
- Prior art date
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- 238000002360 preparation method Methods 0.000 title claims abstract description 33
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- YWIVKILSMZOHHF-QJZPQSOGSA-N sodium;(2s,3s,4s,5r,6r)-6-[(2s,3r,4r,5s,6r)-3-acetamido-2-[(2s,3s,4r,5r,6r)-6-[(2r,3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2- Chemical compound [Na+].CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 YWIVKILSMZOHHF-QJZPQSOGSA-N 0.000 claims description 6
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- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims description 2
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Classifications
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- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
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- A—HUMAN NECESSITIES
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
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- A—HUMAN NECESSITIES
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- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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Abstract
The invention relates to a plant repairing composition containing aloe, a preparation method and application thereof, belonging to the technical field of cosmetic compositions. The aloe-containing plant repairing composition provided by the invention comprises the following components: aloe vera extract, cotton rose extract, kangaroo paw extract; the mass ratio of the aloe vera extract to the cotton rose extract to the kangaroo paw extract is (0.5-4): 0.2-3): 0.3-3. The aloe-containing plant repairing composition is prepared by adding various plant extracts, does not contain chemical preparations such as preservative and the like, is harmless to human bodies, and can be used for a long time; the cooperation of multiple plant extracts can play a role in synergy, strengthen the cell 'defensive fort' from inside to outside, and achieve ideal repairing effect.
Description
Technical Field
The invention belongs to the technical field of cosmetic compositions, and particularly relates to a plant repairing composition containing aloe, and a preparation method and application thereof.
Background
Skin is the first barrier of our human body facing the external environment, and whether the skin barrier is well developed or not is vital. With age, the stratum corneum of the skin becomes thinner, and the function of the protective layer is weakened; smoke, UVA and UVB in ultraviolet light, infrared light, etc. all generate free ions (free radicals) to damage the skin lipid protection layer and damage the skin; disorders of stress, diet and work and rest, etc., also weaken the natural resistance of the skin, leading to a decrease in skin self-repair function, and chronic inflammation and hormone-dependent dermatitis, in which the skin barrier is damaged due to improper use of cosmetics. Once the skin is subjected to such injuries or irritation, and the skin protection function is reduced, the allergic phenomena such as redness, swelling, pain, itching or pimple desquamation are caused.
Therefore, developing a safe, effective, non-toxic and side-effect repair cosmetic with the functions of repairing skin barrier, deep moisturizing and improving skin tolerance has been one of research hotspots in the cosmetic field. The repairing cosmetics have become the preferred care products for people with sensitive skin due to the advantages of mild effect, small side effect, no skin dependence and the like. However, the existing repairing products still have the problem that the repairing effect cannot be expected.
Disclosure of Invention
The invention aims at solving the problems existing in the existing products and provides a plant repairing composition containing aloe, a preparation method and application thereof.
The invention is realized by the following technical scheme:
the invention provides an aloe-containing plant repairing composition, which comprises the following components: aloe vera extract, cotton rose extract, kangaroo paw extract; the mass ratio of the aloe vera extract to the cotton rose extract to the kangaroo paw extract is (0.5-4): 0.2-3): 0.3-3.
The aloe-containing plant repairing composition is prepared by adding various plant extracts, does not contain chemical preparations such as preservative and the like, is harmless to human bodies, and can be used for a long time; the aloe vera extract added in the aloe plant repairing composition is rich in various amino acids and natural whitening and moisturizing factors, has extremely high permeability, can be directly absorbed by skin, and can decompose and convert pigmentation, so that the natural moisturizing and whitening effects are achieved; meanwhile, the product is rich in monosaccharide, polysaccharide, vitamin and mineral substances, has obvious effect of delaying cell aging, can reduce wrinkle, and has the effects of supplementing water, diminishing inflammation, resisting bacteria, moistening, removing peculiar smell and the like. The extract of Hibiscus Mutabilis flower added in the aloe plant repairing composition contains flavonoid compounds, polyphenol acids, anthocyanin and other substances, and has the effects of detumescence, pus discharge and pain relief. The kangaroo claw extract added into the aloe-containing plant repairing composition is rich in high content of fructose, rutin and polyphenol, can improve the framework of dermis, reduce wrinkle appearance, reduce skin relaxation, can activate fibroblasts, increase the contractility of the fibroblasts, and help skin cells to repair. The three plant extracts are scientifically combined, so that the synergistic effect of the three plant extracts in repairing is effectively exerted, the 'defense fort' of cells can be strengthened from inside to outside, and the repairing effect with remarkable effect is achieved.
As a preferred embodiment of the aloe vera-containing plant repair composition of the present invention, the aloe vera extract is at least two of aloe vera flower extract, aloe vera leaf juice.
As a preferred embodiment of the aloe plant repairing composition, the mass ratio of the aloe vera flower extract, the aloe vera leaf extract and the aloe vera leaf juice is (0.1-2): (0.5-3): (0.4-15).
It is still another object of the present invention to provide a method for preparing the aloe-containing plant repair composition, comprising the steps of:
(1) Adding pulverized flos Hibisci Mutabilis or Aloe vera into water (preferably deionized water), heating and stirring, cooling, centrifuging to obtain supernatant, concentrating, and vacuum freeze drying to obtain flos Hibisci Mutabilis extract or Aloe vera extract;
(2) Collecting Kangaroo, cleaning, oven drying, pulverizing, adding into solvent (preferably water or 60% -95% ethanol solution), heating, ultrasonic treating, cooling, centrifuging to obtain supernatant, filtering to obtain filtrate, concentrating, and vacuum lyophilizing to obtain Kangaroo extract;
(3) Mixing the obtained flos Hibisci Mutabilis extract, aloe vera extract and Kangaroo extract at the above mass ratio.
As a preferred embodiment of the preparation method of the aloe-containing plant repairing composition, in the step (1), the mass ratio of the cotton rose to the water is 1: (10-15).
Preferably, in the step (1), the heating temperature is 50-80 ℃ and the heating time is 100-140 min; the rotational speed of the centrifugation is 3000rpm-5000rpm, and the time is 10min-15min; according to the preparation method, the preservative film is covered in the heating process to reduce liquid evaporation, and meanwhile, the whole extraction process is carried out for 2-3 times, so that the effective components in the cotton rose are fully extracted.
Preferably, in the step (2), the temperature of the drying is 40-50 ℃; the solvent is 60% -95% ethanol solution; the heating temperature is 40-60 ℃, the time is 10-45min, and the ultrasonic frequency is 20kHz; the rotational speed of the centrifugation is 4000rpm-4500rpm, and the time is 15min-25min; the filtration is reduced pressure filtration and/or membrane ultrafiltration.
As a preferred embodiment of the method for preparing aloe-containing plant repairing composition of the present invention, in the step (1) and the step (2), the vacuum freeze-drying pressure is 60Pa to 65Pa, and the time is 1.5h to 2h.
The invention further aims to provide a repair mask which comprises the following components in percentage by mass: the aloe-containing plant repairing composition provided by the invention comprises 0.5% -10% of a humectant 0.3% -13%, 0.1% -1% of an antioxidant, 0.01% -0.5% of a chelating agent and the balance of water.
As a preferred embodiment of the repairing mask of the present invention, the humectant is at least one of glycerin, butylene glycol, dipropylene glycol, panthenol, 1, 2-pentanediol, 1, 2-hexanediol, isopentyl glycol, ethyl-hexylglycerin, sodium hyaluronate, hydrolyzed sodium hyaluronate, acetylated sodium hyaluronate, squalane, trehalose, xylitol-based glucoside, fructo-oligosaccharides; the antioxidant is at least one of p-hydroxyacetophenone and tocopheryl acetate; the chelating agent is at least one of EDTA disodium, sodium citrate and octanoyl hydroxamic acid.
Preferably, the repairing facial mask further comprises 0.1% -0.5% of skin conditioning agent; the skin conditioning agent is selectively added according to actual needs.
It is a further object of the present invention to provide the use of the aloe vera-containing plant repair composition in cosmetics and/or pharmaceuticals.
As a preferred embodiment of the application of the aloe plant repairing composition in cosmetics and/or medicines, the aloe plant repairing composition accounts for 0.5% -10% of the total mass of the cosmetics or medicines.
The compositions of the present invention may be used in a variety of different applications to form a variety of different formulations, without particular limitation. In particular, the composition of the present invention is applicable to dosage forms including lotions, emollients, lotions, moisturizers, moisturisers, nutritional emulsions, massage creams, nutritional creams, moisturisers, hand creams, foundations, essences, nutritional essences, masks, soaps, facial cleansing foams, facial cleansing emulsions, facial cleansing creams, body lotions and body washes.
The beneficial effects of the invention are as follows:
(1) The composition is prepared by adding various plant extracts, does not contain chemical preparations such as preservative and the like, is harmless to the body, and can be used for a long time.
(2) The invention can play a role in synergy by the cooperation of a plurality of plant extracts, strengthen the cell 'defensive fort' from inside to outside, and achieve ideal repairing effect.
(3) The mask provided by the invention has the advantages that no alcohol and essence are added, the components are mild, the hyaluronic acid is used for thickening, the texture is soft and moist and not sticky, the skin is repaired, the skin defensive power is improved, the polyol such as panthenol is added for basic moisturizing, the skin is moistened, the plant repairing composition can be used for repairing the skin barrier together, the fragile damaged skin is improved, the application range is wide, and the sensitive muscle can be used.
Detailed Description
For a better description of the objects, technical solutions and advantages of the present invention, the present invention will be further described with reference to the following specific examples. It will be appreciated by persons skilled in the art that the specific embodiments described herein are for purposes of illustration only and are not intended to be limiting.
The test methods used in the examples are conventional methods unless otherwise specified; the materials, reagents and the like used, unless otherwise specified, are all commercially available.
Example 1
A plant repairing composition containing aloe comprises, by weight, 50 parts of aloe vera extract, 20 parts of cotton rose extract, and 30 parts of kangaroo claw extract.
The aloe vera extract comprises the following components in percentage by mass: aloe vera flower extract: aloe vera leaf extract: aloe vera leaf juice = 1:5:4.
the preparation method of the cotton rose extract comprises the following steps: taking 100g of Hibiscus flower, crushing, adding 1000mL of deionized water, stirring and heating to 70 ℃ for reacting for 120min (covering a preservative film to reduce evaporation); stopping heating, and centrifuging at 4000rpm for 15min when the water is cooled to room temperature, and collecting supernatant; extracting for three times, combining and concentrating the supernatant after each extraction, and performing vacuum freeze drying to obtain the cotton rose extract.
The preparation method of the aloe vera extract is the same as that of the cotton rose extract.
The preparation method of the kangaroo paw extract comprises the following steps: collecting Kangaroo, cleaning with distilled water, oven drying at 45deg.C to constant weight, pulverizing to obtain Kangaroo pollen, adding 75% ethanol solution, extracting with ultrasonic assistance at 60deg.C for 70min at a ratio of 1:20, standing at room temperature for natural cooling, centrifuging at 4200rpm for 20min, filtering under reduced pressure, ultrafiltering with filter membrane, and collecting filtrate; concentrating the collected filtrate, and vacuum freeze-drying to obtain the kangaroo claw flower extract.
In the preparation of the extract, the vacuum freeze-drying pressure is 60Pa, the temperature is-10 ℃ and the time is 2 hours.
Mixing the flos Hibisci Mutabilis extract, kangaroo extract and Aloe Vera extract at a certain proportion to obtain the plant repairing composition containing Aloe.
Example 2
A plant repairing composition containing aloe comprises, by weight, 50 parts of aloe vera extract, 25 parts of cotton rose extract and 25 parts of kangaroo claw extract.
The aloe vera extract comprises the following components in percentage by mass: aloe vera flower extract: aloe vera leaf extract: aloe vera leaf juice = 1:5:4.
the preparation method of the cotton rose extract, the aloe vera extract and the kangaroo paw extract is the same as that of example 1.
Mixing the flos Hibisci Mutabilis extract, kangaroo extract and Aloe Vera extract at a certain proportion to obtain the plant repairing composition containing Aloe.
Example 3
A plant repairing composition containing aloe comprises, by weight, 50 parts of aloe vera extract, 20 parts of cotton rose extract, and 30 parts of kangaroo claw extract.
The aloe vera extract comprises the following components in percentage by mass: aloe vera flower extract: aloe vera leaf extract: aloe vera leaf juice = 1:2:7.
the preparation method of the cotton rose extract, the aloe vera extract and the kangaroo paw extract is the same as that of example 1.
Mixing the flos Hibisci Mutabilis extract, kangaroo extract and Aloe Vera extract at a certain proportion to obtain the plant repairing composition containing Aloe.
Example 4
A plant repairing composition containing aloe comprises, by weight, 50 parts of aloe vera extract, 50 parts of cotton rose extract and 50 parts of kangaroo claw extract.
The aloe vera extract comprises the following components in percentage by mass: aloe vera flower extract: aloe vera leaf extract: aloe vera leaf juice = 1:5:4.
the preparation method of the cotton rose extract, the aloe vera extract and the kangaroo paw extract is the same as that of example 1.
Mixing the flos Hibisci Mutabilis extract, kangaroo extract and Aloe Vera extract at a certain proportion to obtain the plant repairing composition containing Aloe.
Example 5
A plant repairing composition containing aloe comprises 40 parts of aloe vera extract, 30 parts of cotton rose extract and 30 parts of kangaroo paw extract in parts by weight.
The aloe vera extract comprises the following components in percentage by mass: aloe vera flower extract: aloe vera leaf extract: aloe vera leaf juice = 1:2:7.
the preparation method of the cotton rose extract, the aloe vera extract and the kangaroo paw extract is the same as that of example 1.
Mixing the flos Hibisci Mutabilis extract, kangaroo extract and Aloe Vera extract at a certain proportion to obtain the plant repairing composition containing Aloe.
Example 6
A plant repairing composition containing aloe comprises 40 parts of aloe vera extract, 30 parts of cotton rose extract and 30 parts of kangaroo paw extract in parts by weight.
The aloe vera extract comprises the following components in percentage by mass: aloe vera flower extract: aloe vera leaf extract: aloe vera leaf juice = 1:5:4.
the preparation method of the cotton rose extract, the aloe vera extract and the kangaroo paw extract is the same as that of example 1.
Mixing the flos Hibisci Mutabilis extract, kangaroo extract and Aloe Vera extract at a certain proportion to obtain the plant repairing composition containing Aloe.
Comparative example 1
A plant repairing composition containing aloe comprises, by weight, 50 parts of aloe vera extract and 50 parts of Hibiscus Mutabilis extract.
The aloe vera extract comprises the following components in percentage by mass: aloe vera flower extract: aloe vera leaf extract: aloe vera leaf juice = 1:5:4.
the preparation method of the cotton rose extract and the aloe vera extract is the same as that of example 1.
Mixing the flos Hibisci Mutabilis extract and Aloe vera extract at a certain proportion to obtain the plant repairing composition containing Aloe.
Comparative example 2
A plant repairing composition containing aloe comprises, by weight, 50 parts of aloe vera extract and 50 parts of kangaroo claw extract.
The aloe vera extract comprises the following components in percentage by mass: aloe vera flower extract: aloe vera leaf extract: aloe vera leaf juice = 1:5:4.
wherein aloe vera extract and kangaroo paw extract were prepared as in example 1.
And uniformly mixing the kangaroo claw extract and the aloe vera extract according to a proportion to obtain the aloe plant repairing composition.
Comparative example 3
A plant repairing composition comprises 50 parts of cotton rose extract and 50 parts of kangaroo claw extract in parts by weight.
The preparation methods of the cotton rose extract and the kangaroo paw extract are the same as in example 1.
And uniformly mixing the cotton rose extract and the kangaroo claw extract according to a proportion to obtain the plant repairing composition.
Comparative example 4
A plant repairing composition comprises aloe vera extract 100 parts.
The aloe vera extract comprises the following components in percentage by mass: aloe vera flower extract: aloe vera leaf extract: aloe vera leaf juice = 1:5:4.
wherein aloe vera extract was prepared in the same manner as in example 1.
And uniformly mixing the aloe vera extract according to a proportion to obtain the plant repairing composition.
Comparative example 5
A plant repairing composition comprises 100 parts of Hibiscus flower extract.
The preparation method of the cotton rose extract is the same as that of example 1.
Comparative example 6
A plant repairing composition comprises Kangaroo paw extract 100 parts.
Wherein kangaroo paw extract was prepared in the same manner as in example 1.
Comparative example 7
A plant repairing composition containing aloe comprises, by weight, 4 parts of aloe vera extract, 20 parts of cotton rose extract, and 30 parts of kangaroo claw extract.
The aloe vera extract comprises the following components in percentage by mass: aloe vera flower extract: aloe vera leaf extract: aloe vera leaf juice = 1:5:4.
the preparation method of the cotton rose extract, the aloe vera extract and the kangaroo paw extract is the same as that of example 1.
Mixing the flos Hibisci Mutabilis extract, kangaroo extract and Aloe Vera extract at a certain proportion to obtain the plant repairing composition containing Aloe.
Comparative example 8
A plant repairing composition containing aloe comprises, by weight, 500 parts of aloe vera extract, 20 parts of cotton rose extract, and 30 parts of kangaroo claw extract.
The aloe vera extract comprises the following components in percentage by mass: aloe vera flower extract: aloe vera leaf extract: aloe vera leaf juice = 1:5:4.
the preparation method of the cotton rose extract, the aloe vera extract and the kangaroo paw extract is the same as that of example 1.
Mixing the flos Hibisci Mutabilis extract, kangaroo extract and Aloe Vera extract at a certain proportion to obtain the plant repairing composition containing Aloe.
Comparative example 9
A plant repairing composition containing aloe comprises, by weight, 50 parts of aloe vera extract, 10 parts of cotton rose extract, and 30 parts of kangaroo claw extract.
The aloe vera extract comprises the following components in percentage by mass: aloe vera flower extract: aloe vera leaf extract: aloe vera leaf juice = 1:5:4.
the preparation method of the cotton rose extract, the aloe vera extract and the kangaroo paw extract is the same as that of example 1.
Mixing the flos Hibisci Mutabilis extract, kangaroo extract and Aloe Vera extract at a certain proportion to obtain the plant repairing composition containing Aloe.
Comparative example 10
A plant repairing composition containing aloe comprises, by weight, 50 parts of aloe vera extract, 400 parts of cotton rose extract, and 30 parts of kangaroo claw extract.
The aloe vera extract comprises the following components in percentage by mass: aloe vera flower extract: aloe vera leaf extract: aloe vera leaf juice = 1:5:4.
the preparation method of the cotton rose extract, the aloe vera extract and the kangaroo paw extract is the same as that of example 1.
Mixing the flos Hibisci Mutabilis extract, kangaroo extract and Aloe Vera extract at a certain proportion to obtain the plant repairing composition containing Aloe.
Comparative example 11
A plant repairing composition containing aloe comprises, by weight, 50 parts of aloe vera extract, 30 parts of cotton rose extract, and 20 parts of kangaroo claw extract.
The aloe vera extract comprises the following components in percentage by mass: aloe vera flower extract: aloe vera leaf extract: aloe vera leaf juice = 1:5:4.
the preparation method of the cotton rose extract, the aloe vera extract and the kangaroo paw extract is the same as that of example 1.
Mixing the flos Hibisci Mutabilis extract, kangaroo extract and Aloe Vera extract at a certain proportion to obtain the plant repairing composition containing Aloe.
Comparative example 12
A plant repairing composition containing aloe comprises, by weight, 50 parts of aloe vera extract, 20 parts of cotton rose extract, and 400 parts of kangaroo claw extract.
The aloe vera extract comprises the following components in percentage by mass: aloe vera flower extract: aloe vera leaf extract: aloe vera leaf juice = 1:5:4.
the preparation method of the cotton rose extract, the aloe vera extract and the kangaroo paw extract is the same as that of example 1.
Mixing the flos Hibisci Mutabilis extract, kangaroo extract and Aloe Vera extract at a certain proportion to obtain the plant repairing composition containing Aloe.
Comparative example 13
A plant repairing composition containing aloe comprises, by weight, 50 parts of aloe vera extract, 20 parts of cotton rose extract, and 30 parts of kangaroo claw extract.
The aloe vera extract comprises the following components in percentage by mass: aloe vera flower extract: aloe vera leaf extract = 1:5.
the preparation method of the cotton rose extract, the aloe vera extract and the kangaroo paw extract is the same as that of example 1.
Mixing the flos Hibisci Mutabilis extract, kangaroo extract and Aloe Vera extract at a certain proportion to obtain the plant repairing composition containing Aloe.
Comparative example 14
A plant repairing composition containing aloe comprises, by weight, 50 parts of aloe vera extract, 20 parts of cotton rose extract, and 30 parts of kangaroo claw extract.
The aloe vera extract comprises the following components in percentage by mass: aloe vera leaf extract: aloe vera leaf juice = 5:4.
the preparation method of the cotton rose extract, the aloe vera extract and the kangaroo paw extract is the same as that of example 1.
Mixing the flos Hibisci Mutabilis extract, kangaroo extract and Aloe Vera extract at a certain proportion to obtain the plant repairing composition containing Aloe.
Comparative example 15
A plant repairing composition containing aloe comprises, by weight, 50 parts of aloe vera extract, 20 parts of cotton rose extract, and 30 parts of kangaroo claw extract.
The aloe vera extract comprises the following components in percentage by mass: aloe vera flower extract: aloe vera leaf juice = 1:4.
the preparation method of the cotton rose extract, the aloe vera extract and the kangaroo paw extract is the same as that of example 1.
Mixing the flos Hibisci Mutabilis extract, kangaroo extract and Aloe Vera extract at a certain proportion to obtain the plant repairing composition containing Aloe.
Product safety test
1. Number of test persons: 30 people, 4 men and 26 women;
2. the testing method comprises the following steps: the plant repair compositions of examples 1 to 6 and comparative examples 1 to 15 were subjected to patch test. Selecting a qualified patch tester, placing about 0.020g of a test object into the patch tester by a closed patch test method, applying a control group which is a blank control (without any substances) external medical adhesive tape on the back of a subject, removing the test object after 24 hours, observing skin reactions after 0.5, 24 and 48 hours after removing the patch, and recording the results according to skin reaction grading standards in cosmetic safety technical Specification (2015).
3. The evaluation criteria are shown in Table 1 below.
4. The test results are shown in Table 2.
TABLE 1 skin adverse reaction grading criteria
Table 2 test results
As can be seen from the skin patch test results in Table 2, the plant repairing compositions containing aloe in examples 1 to 6 are high in skin safety, free from irritation to human body and capable of being used with ease; by analyzing comparative examples 7 to 12, it was found that when the fraction of a certain plant extract was too high, suspicious reactions were caused in a small number of people.
Chilli oil stimulation repair experiment
To evaluate the repair effect of the different examples and comparative examples, 220 normal skin groups were selected and randomly divided into 22 groups, and the capsicum oil stimulation repair experiments were performed on examples 1 to 6 and comparative examples 1 to 15 and the blank control group, respectively.
The specific test method for the capsicum oil stimulation repair experiment comprises the following steps: the left and right forearms of volunteers are cleaned under the environment that the temperature is 20-26 ℃ and the relative humidity is 50% -60%, square areas (50 mm multiplied by 50 mm) are randomly defined on the left and right forearms, equal amount of capsicum oil is smeared in the areas, after the left and right forearms are stimulated for 20min, the capsicum oil is washed out by hot water at 45 ℃, the areas coated with the capsicum oil are respectively smeared with the above-mentioned examples 1-6 and comparative examples 1-15, the blank control group is not smeared with any product, the red and swollen condition of the forearms is observed at intervals, and the time of complete pain relief and the time of complete reddening of the forearms are recorded. The test results are shown in table 3 below:
table 3 experiment for stimulating and repairing capsicum oil
From the above experimental results, the compounding effect of examples 1 to 6 is significantly better than that of the single plant extract/two plant extracts of comparative examples 1 to 6, indicating that there is a synergistic effect between the compositions of the present invention. Meanwhile, the repairing effect of examples 1-6 is also better than that of comparative examples 7-15, which shows that the plant repairing composition of the invention has excellent repairing effect based on the specific proportioning content of each component in the composition.
Wherein, the capsicum oil in examples 1,2, 4 and 6 has a stimulating and repairing effect which can completely relieve pain and remove redness within half an hour.
The masks of application examples 1 to 4 were prepared from examples 1,2, 4 and 6, and the masks of application examples 1 to 6 were prepared from comparative examples 1 to 6, and the formulation of the masks is shown in Table 4.
Table 4 mask formulation table (mass percent/%)
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The aloe-containing plant repairing composition of comparative examples 7 to 15 was also prepared into a mask of application comparative examples 7 to 15, wherein the components and contents of the moisturizer, the antioxidant, and the chelating agent were the same as those of application comparative example 1, and water was 100%.
The skin moisture loss test was performed on volunteers using the mask, while allowing the volunteers to self-evaluate skin conditions (redness, itching) by questionnaire.
Percutaneous moisture loss Test (TEWL)
The testing method comprises the following steps: selecting 190 volunteers with age between 25 and 50 years, sensitive face and obvious symptoms of redness, itching and dryness, dividing the volunteers into 19 groups of 10 people, keeping average skin conditions of each group as close as possible, testing initial TEWL of facial skin, and performing facial mask trial once every three days; the masks of application examples 1 to 4 and comparative examples 1 to 15 were applied, and TEWL was tested on days 0, 4, 7, 12, respectively. The volunteers were also allowed to self-evaluate skin conditions (redness, itching) and count the results.
TEWL is a very important parameter for assessing the function of the skin moisture barrier, and has been widely accepted internationally to reflect the integrity of the skin barrier function. Standard TEWL is measured in the dry, antiperspirant state of the skin at ambient temperature 24 ℃ and ambient humidity 50%, and the test data are obtained under these conditions.
The TEWL value decrease rate is calculated as follows: TEWL value decrease rate (%) = (T) 0 -T n )/T 0 X 100% in T 0 For an initial TEWL value, T n TEWL values for different test time points.
TABLE 5 percutaneous moisture loss test results
From the experimental results of the percutaneous moisture loss test, compared with application comparative examples 1-6, the average decrease rate of the TEWL value of application examples 1-4 is more than 55% at 12 days, namely the skin barrier function is repaired, which indicates that the aloe-containing plant repair composition of the invention can effectively repair the skin barrier; the skin repair effect of application example 1 was superior to that of application comparative examples 7 to 15, indicating that the mask made of the aloe vera-containing plant repair composition of the present invention has an excellent effect of repairing skin barrier based on the components in the specific ratio range.
Table 6 volunteer self-assessment test results
Experimental results show that the skin redness and itching symptoms of volunteers on which the mask of application examples 1-4 is used are greatly improved, the ratio of the obvious improvement to the great improvement is more than 80%, and the aloe-containing plant repairing composition has obvious effect of improving the skin redness and itching and good skin repairing effect; compared with application example 1, in the facial mask prepared in application comparative examples 1-6, the components of the plant repairing composition lack one or two of aloe vera extract, cotton rose extract and kangaroo paw extract, and the synergistic effect is reduced, so that the repairing effect is affected; in the facial mask prepared in the comparative examples 7-12, the components of the plant repairing composition, namely aloe vera extract, cotton rose extract and kangaroo claw extract, are in imbalance proportion, so that the synergistic effect of the three components is affected, and the repairing effect is reduced; in the mask prepared by using comparative examples 13 to 15, the aloe vera extract of the plant repairing composition lacks any one of aloe vera leaf extract, aloe vera leaf extract and aloe vera leaf juice, and the synergistic effect of the three is reduced, so that the repairing effect of the mask is poor.
Finally, it should be noted that the above embodiments are only for illustrating the technical solution of the present invention and not for limiting the scope of the present invention, and although the present invention has been described in detail with reference to the preferred embodiments, it should be understood by those skilled in the art that the technical solution of the present invention may be modified or substituted equally without departing from the spirit and scope of the technical solution of the present invention.
Claims (9)
1. An aloe-containing plant repair composition, comprising the following components: aloe vera extract, cotton rose extract, kangaroo paw extract; the mass ratio of the aloe vera extract to the cotton rose extract to the kangaroo paw extract is (0.5-4): 0.2-3): 0.3-3; the aloe vera extract is composed of aloe vera flower extract, aloe vera leaf extract and aloe vera leaf juice.
2. The aloe vera-containing plant repair composition of claim 1, wherein the mass ratio of aloe vera flower extract, aloe vera leaf juice is (0.1-2): 0.5-3): 0.4-15.
3. A method of preparing an aloe vera-containing plant repair composition of claim 1, comprising the steps of:
(1) Adding pulverized flos Hibisci Mutabilis or Aloe vera into water, heating and stirring, cooling, centrifuging to obtain supernatant, concentrating, and vacuum freeze drying to obtain flos Hibisci Mutabilis extract or Aloe vera extract;
(2) Collecting Kangaroo claw, cleaning, oven drying, pulverizing, adding into solvent, heating, ultrasonic treating, cooling, centrifuging to obtain supernatant, filtering to obtain filtrate, concentrating, and vacuum lyophilizing to obtain Kangaroo claw extract;
(3) Mixing the obtained flos Hibisci Mutabilis extract, aloe vera extract and Kangaroo extract at the above mass ratio.
4. The method for preparing aloe-containing plant repairing composition according to claim 3, wherein in the step (1), the mass ratio of the cotton rose to the water is 1: (10-15).
5. A method of preparing an aloe vera-containing plant repair composition according to claim 3 wherein the vacuum freeze-drying pressure in step (1) and step (2) is from 60Pa to 65Pa for a period of from 1.5h to 2h.
6. The repairing facial mask is characterized by comprising the following components in percentage by mass: the aloe-containing plant repair composition of claim 1 or 2, 0.5% -10%, humectant 0.3% -13%, antioxidant 0.1% -1%, chelating agent 0.01% -0.5%, and the balance being water.
7. The repairing facial mask of claim 6, wherein said humectant is at least one of glycerin, butylene glycol, dipropylene glycol, panthenol, 1, 2-pentanediol, 1, 2-hexanediol, isopentane diol, ethyl-hexylglycerin, sodium hyaluronate, hydrolyzed sodium hyaluronate, acetylated sodium hyaluronate, squalane, trehalose, xylitol-based glucoside, fructooligosaccharides; the antioxidant is at least one of p-hydroxyacetophenone and tocopheryl acetate; the chelating agent is at least one of EDTA disodium, sodium citrate and octanoyl hydroxamic acid.
8. Use of an aloe vera-containing plant repair composition according to claim 1 or 2 in cosmetics and/or in the preparation of a medicament.
9. Use of an aloe vera-containing plant repair composition according to claim 8 in cosmetics and/or in the preparation of a medicament, characterized in that the aloe vera-containing plant repair composition comprises 0.5% to 10% of the total mass of the cosmetic or the medicament.
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| US8486463B1 (en) * | 2012-05-09 | 2013-07-16 | L'oreal | Cosmetic composition comprising aloe vera and caprylyl salicylic acid and method of making |
| WO2018073714A1 (en) * | 2016-10-17 | 2018-04-26 | International Flavors & Fragrances Inc | Extract of anigozanthos flavidus for cosmetic use |
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