CN109394615B - Soothing and repairing composition containing various plant extracts - Google Patents
Soothing and repairing composition containing various plant extracts Download PDFInfo
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- CN109394615B CN109394615B CN201811373564.4A CN201811373564A CN109394615B CN 109394615 B CN109394615 B CN 109394615B CN 201811373564 A CN201811373564 A CN 201811373564A CN 109394615 B CN109394615 B CN 109394615B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/645—Proteins of vegetable origin; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
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Abstract
The invention discloses a soothing and repairing composition containing various plant extracts, and belongs to the technical field of cosmetic formulas. The soothing and repairing composition is prepared from the following components in parts by weight: 1 to 10 percent of humectant, 3 to 10 percent of soothing and repairing agent, 0.1 to 3 percent of preservative and the balance of deionized water. The soothing and repairing agent comprises hydrolyzed lupin protein, carob seed extract and vegetarian flower extract. The composition has remarkable relieving and repairing effects, can effectively relieve the problems of red swelling, pain, itch, papule desquamation and the like after skin is stimulated, can quickly repair the damaged barrier function of the skin, and improves the capability of the skin to deal with external damage. The recommended level of addition of the soothing repair composition is 2% to 8% depending on the product formulation. The composition has the advantages of natural non-irritation, obvious effect of relieving and repairing, and the like.
Description
Technical Field
The invention belongs to the technical field of cosmetic formulas, and particularly relates to a soothing and repairing composition containing various plant extracts.
Background
Statistics have stated that about 65% of the world population is suffering or has suffered from skin sensitivity problems. The skin allergy is caused by factors inherent in the human body and external factors such as the environment. With the increase of age, the stratum corneum of the skin becomes thinner, and the function of a protective layer is weakened; smog, dust, UVA and UVB in ultraviolet rays, infrared rays and the like can generate free ions (free radicals) to damage the lipid protective layer of the skin so as to damage the skin; stress, mental stress and depressed mood also weaken the natural resistance of the skin, causing its self-maintenance function to decline. In addition, various additives in cosmetics have a more or less irritating effect on the skin. When the skin is subjected to such damage or irritation, and the skin protective function is reduced, allergic phenomena such as redness, swelling, pain, itching or papular desquamation can occur. Although the glucocorticoid used conventionally can quickly relieve the skin allergy, the glucocorticoid usually has some side effects, such as skin atrophy, telangiectasia, purpura, acne pigment abnormality, light allergy and the like caused by long-term use, and long-term hormone treatment can cause skin dependence, thereby bringing endless troubles to many consumers. Therefore, the research and development of a safe, effective and non-toxic anti-allergic cosmetic is one of the research hotspots in the field of cosmetics. The soothing and repairing cosmetics gradually become the first choice care products for people with sensitive skin due to the advantages of mild effect, small side effect, no skin dependence and the like. However, the anti-allergy and soothing repair cosmetics on the market are relatively few, and due to the existence of individual difference, the reasons for allergy of each person are different, so that the using effect of most products is not ideal.
Disclosure of Invention
In response to the problems of the prior art, the present invention provides a soothing and repairing composition containing multiple plant extracts. The plant extracts mentioned in the present invention include hydrolyzed lupin protein, carob seed (Ceratonia SILIQUA) fruit extract and vegetarian flower (Jasminum OFFICINALE) flower extract. The composition can be made into lotion or cream, and has the advantages of no irritation, and good soothing and repairing effects.
In order to solve the technical problems, the invention adopts the following technical scheme:
a soothing and repairing composition containing various plant extracts is prepared from the following components in parts by weight: 1 to 10 percent of humectant, 3 to 10 percent of soothing and repairing agent, 0.1 to 5 percent of preservative and the balance of deionized water.
The soothing and repairing agent is a composition of hydrolyzed lupin protein, carob seed (Ceratonia SILIQUA) fruit extract and vegetarian flower (Jasminum OFFICINALE) flower extract.
The soothing and repairing composition preferably comprises the following plant extracts in parts by weight: the extract of flower of Jasminum OFFICINALE (Jasminum OFFICINALE) is 1.0:2.0: 1.0.
The preservative is one or more of phenoxyethanol, ethylhexyl glycerol, 1, 2-pentanediol and 1, 2-hexanediol.
The humectant is one or more of 1, 3-propylene glycol, butanediol and glycerol.
The preparation method of the soothing and repairing composition comprises the following steps: heating the mixture of water and humectant to 90 deg.C, sterilizing for 30min, cooling to 45 deg.C, adding soothing and repairing agent and antiseptic in proportion, and stirring to obtain soothing and repairing composition containing multiple plant extracts.
The soothing repair composition is used to prepare dosage forms including, but not limited to: soothing repair essence cream and soothing repair cream.
In the application of the soothing and repairing composition, the addition amount of the soothing and repairing composition is 2% -8%, and preferably 4% -8%.
The invention has the beneficial effects that: the beneficial effects of the invention are obtained by adding various plant extracts. Firstly, the extract of the vegetarian fanghua, which is rich in jasmine flavonoid, can effectively inhibit the release of proinflammatory mediators such as interleukin 1 and interleukin-8 which cause skin anaphylactic reaction, promote the defense system of skin cells, and quickly relieve the allergic manifestation of skin. Secondly, by utilizing the characteristic that the hydrolyzed lupin protein is rich in oligosaccharide and glutamine peptide, the synthesis of epidermal protein and lipid is promoted, particularly the synthesis of ceramide is promoted, the barrier function of skin is effectively improved, and a second layer of protection is provided for damaged skin. Finally, the extract of the carob bean (Ceratonia SILIQUA) fruit is capable of promoting cell differentiation, accelerating the regeneration of damaged skin, and minimizing the barrier function of the skin. The three extracts are used in a matching way, so that a synergistic effect can be achieved, the 'defense fort' of cells is enhanced from inside to outside, and an ideal relieving and repairing effect is achieved.
Detailed Description
The present invention will be further described with reference to the following examples. It should be understood that: the following examples are given solely for the purpose of illustration and are not intended to limit the scope of the invention, which is to be construed as broadly as the appended claims.
Example 1
The soothing and repairing composition containing various plant extracts is prepared from the following components in parts by weight: 1, 3-propylene glycol as a humectant, 3% of a soothing and repairing agent, 1.5% of phenoxyethanol as a preservative and the balance of deionized water.
The soothing and repairing agent is a composition comprising hydrolyzed lupin protein, carob seed (Ceratonia SILIQUA) fruit extract and vegetarian flower (Jasminum OFFICINALE) flower extract at a weight ratio of 1.0:2.0: 1.0.
The three extracts are provided by Bisheng trading Co., Ltd, Guangzhou city.
The method of preparation of the soothing and repairing composition of this example was: heating the mixture of water and humectant to 90 deg.C, sterilizing for 30min, cooling to 45 deg.C, adding soothing and repairing agent and antiseptic in proportion, and stirring to obtain soothing and repairing composition containing multiple plant extracts.
Example 2
The soothing and repairing composition containing various plant extracts is prepared from the following components in parts by weight: 10% of humectant butanediol, 10% of soothing repairing agent, 0.5% of preservative ethylhexyl glycerol and the balance of deionized water, wherein the proportions of the three extracts of the soothing repairing agent are the same as those in example 1.
The soothing repairing composition of this example was prepared as in example 1.
Example 3
The soothing and repairing composition containing various plant extracts is prepared from the following components in parts by weight: the moisturizing agent comprises 5% of glycerin as a moisturizing agent, 8% of a soothing repairing agent, 5% of 1, 2-pentanediol as a preservative and the balance of deionized water, wherein the proportions of the three extracts of the soothing repairing agent are the same as those of the example 1.
The soothing repairing composition of this example was prepared as in example 1.
Example 4
The soothing and repairing composition containing various plant extracts is prepared from the following components in parts by weight: 10% of humectant butanediol, 6% of soothing and repairing agent, 3% of preservative 1, 2-hexanediol and the balance of deionized water, wherein the proportions of the three extracts of the soothing and repairing agent are the same as those in example 1.
The soothing repairing composition of this example was prepared as in example 1.
Example 5
The soothing and repairing composition containing various plant extracts is prepared from the following components in parts by weight: humectant 10% (1, 3-propylene glycol 5%, butanediol 5%), soothing and repairing agent 5%, antiseptic 1.6% (ethylhexyl glycerol 0.1%, 1, 2-hexanediol 1.5%), and balancing deionized water,
the soothing repairing composition of this example was prepared as in example 1.
Example 6
The soothing and repairing composition containing various plant extracts is prepared from the following components in parts by weight: 7% of a humectant (2% of butanediol, 2% of glycerol, 3% of glycerol), 4% of a soothing and repairing agent, 3.2% of a preservative (0.2% of ethylhexyl glycerol, 3.0% of 1, 2-pentanediol), and the balance of deionized water, wherein the soothing and repairing agent is the same as in example 1.
The soothing repairing composition of this example was prepared as in example 1.
Example 7
The soothing and repairing composition containing various plant extracts is prepared from the following components in parts by weight: the preservative comprises 8% of humectant (3% of 1, 3-propylene glycol and 5% of glycerol), 7% of soothing and repairing agent, 2.5% of preservative (1% of phenoxyethanol and 1.5% of 1, 2-pentanediol), and the balance of deionized water, wherein the soothing and repairing agent is the same as in example 1.
The soothing repairing composition of this example was prepared as in example 1.
Example 8
The soothing and repairing composition containing various plant extracts is prepared from the following components in parts by weight: 4% of humectant glycerin, 9% of a soothing repairing agent, 1.5% of preservative phenoxyethanol and the balance of deionized water, wherein the soothing repairing agent is the same as the soothing repairing agent in the embodiment 1.
The soothing repairing composition of this example was prepared as in example 1.
Example 9
The soothing and repairing composition containing various plant extracts is prepared from the following components in parts by weight: 3% of butanediol as a humectant, 5.5% of a soothing and repairing agent, 5.0% of 1, 2-pentanediol as a preservative and the balance of deionized water, wherein the soothing and repairing agent is the same as in example 1.
The soothing repairing composition of this example was prepared as in example 1.
Example 10
The soothing and repairing composition containing various plant extracts is prepared from the following components in parts by weight: the preservative comprises 6% of humectant (2% of butanediol, 2% of glycerol, 2% of 1, 3-propylene glycol), 7.5% of soothing and repairing agent, 0.7% of preservative (0.5% of phenoxyethanol, 0.2% of ethylhexyl glycerol) and the balance of deionized water, wherein the soothing and repairing agent is the same as in example 1.
The soothing repairing composition of this example was prepared as in example 1.
The compositions prepared in example 8 were selected as raw materials, and the soothing and repairing products of examples 11 to 15 were prepared on the basis of the selected raw materials, and the soothing and repairing effects of the products were examined.
Example 11 preparation of a soothing and rejuvenating cream containing 2.0% of the composition
The formula of the soothing and repairing essence milk containing 2.0 percent of the composition is as follows:
the preparation process of the skin soothing and repairing essence milk comprises the following steps:
(1) firstly, weighing the raw materials according to the names and the weights of the raw materials in the table;
(2) heating the phase A four raw materials to 85 ℃, and stirring until the phase A four raw materials are completely dissolved;
(3) heating the six raw materials of the phase B to 75 ℃, and stirring until the raw materials are completely dissolved;
(4) adding A, B phase, stirring, and homogenizing at high speed for 4 min. Cooling to 45 deg.C under stirring, adding phase C, stirring, and cooling to room temperature to obtain the final product.
(5) Subpackaging to obtain the finished product.
Example 12 preparation of a soothing and rejuvenating cream containing 4.0% of a soothing and rejuvenating composition
The formula of the soothing and repairing essence milk containing 4.0 percent of the composition is as follows:
the preparation process of the skin soothing and repairing essence milk comprises the following steps:
(1) firstly, weighing the raw materials according to the names and the weights of the raw materials in the table;
(2) heating the phase A four raw materials to 85 ℃, and stirring until the phase A four raw materials are completely dissolved;
(3) heating the six raw materials of the phase B to 75 ℃, and stirring until the raw materials are completely dissolved;
(4) adding A, B phase, stirring, and homogenizing at high speed for 4 min. Cooling to 45 deg.C under stirring, adding phase C, stirring, and cooling to room temperature to obtain the final product.
(5) Subpackaging to obtain the finished product.
Example 13 preparation of a soothing repair cream containing 6.0% of a soothing repair composition
The formula of the soothing and repairing essence milk containing 6.0 percent of the composition is as follows:
the preparation process of the skin soothing and repairing essence milk comprises the following steps:
(1) firstly, weighing the raw materials according to the names and the weights of the raw materials in the table;
(2) heating the phase A four raw materials to 85 ℃, and stirring until the phase A four raw materials are completely dissolved;
(3) heating the six raw materials of the phase B to 75 ℃, and stirring until the raw materials are completely dissolved;
(4) adding A, B phase, stirring, and homogenizing at high speed for 4 min. Cooling to 45 deg.C under stirring, adding phase C, stirring, and cooling to room temperature to obtain the final product.
(5) Subpackaging to obtain the finished product.
Example 14 preparation of a soothing moisturizer containing 6.0% of a soothing moisturizer composition
The formula of the soothing repair cream containing 6.0 percent of the composition is as follows:
the preparation process of the skin soothing and repairing essence milk comprises the following steps:
(1) firstly, weighing the raw materials according to the names and the weights of the raw materials in the table;
(2) heating the phase A four raw materials to 85 ℃, and stirring until the phase A four raw materials are completely dissolved;
(3) heating the six raw materials of the phase B to 75 ℃, and stirring until the raw materials are completely dissolved;
(4) adding A, B phase, stirring, and homogenizing at high speed for 6 min. Cooling to 45 deg.C under stirring, adding phase C, stirring, and cooling to room temperature to obtain the final product.
(5) Subpackaging to obtain the finished product.
Example 15 preparation of a soothing treatment cream containing 8.0% of the composition
The formula of the soothing repair cream containing 8.0 percent of the composition is as follows:
the preparation process of the skin soothing and repairing cream comprises the following steps:
(1) firstly, weighing the raw materials according to the names and the weights of the raw materials in the table;
(2) heating the phase A four raw materials to 85 ℃, and stirring until the phase A four raw materials are completely dissolved;
(3) heating the six raw materials of the phase B to 75 ℃, and stirring until the raw materials are completely dissolved;
(4) adding A, B phase, stirring, and homogenizing at high speed for 4 min. Cooling to 45 deg.C under stirring, adding phase C, stirring, and cooling to room temperature to obtain the final product.
(5) Subpackaging to obtain the finished product.
Comparative example 1 (preparation of a repair cream containing 6.0% soothing repair composition)
The soothing and repairing composition used in the comparative example is prepared from the following components in parts by weight: humectant glycerin 4%, hydrolyzed lupin protein extract 9%, antiseptic phenoxyethanol 1.5%, and the balance of deionized water.
The other components of the repair cream, soothing and repairing composition of this comparative example were the same as example 14, with 6.0% of the soothing and repairing composition.
Comparative example 2 (preparation of a repair cream containing 6.0% soothing repair composition)
The soothing and repairing composition used in the comparative example is prepared from the following components in parts by weight: humectant glycerin 4%, carob seed fruit extract 9%, preservative phenoxyethanol 1.5%, and the balance of deionized water.
The other components of the repair cream, soothing and repairing composition of this comparative example were the same as example 14, with 6.0% of the soothing and repairing composition.
Comparative example 3 (preparation of a repair cream containing 6.0% soothing repair composition)
The soothing and repairing composition used in the comparative example is prepared from the following components in parts by weight: humectant glycerin 4%, extract of maigre fanghua 9%, antiseptic phenoxyethanol 1.5%, and the balance of deionized water.
The other components of the repair cream, soothing and repairing composition of this comparative example were the same as example 14, with 6.0% of the soothing and repairing composition.
Comparative example 4 (preparation of a repair cream containing 6.0% soothing repair composition)
The soothing and repairing composition used in the comparative example is prepared from the following components in parts by weight: humectant glycerin 4%, hydrolyzed lupin protein 3%, carob seed fruit extract 6%, antiseptic phenoxyethanol 1.5%, and the balance of deionized water.
The other components of the repair cream, soothing and repairing composition of this comparative example were the same as example 14, with 6.0% of the soothing and repairing composition.
Comparative example 5 (preparation of a repair cream containing 6.0% soothing repair composition)
The soothing and repairing composition used in the comparative example is prepared from the following components in parts by weight: humectant glycerin 4%, carob seed fruit extract 6%, vegetarian flower extract 3%, preservative phenoxyethanol 1.5%, and the balance of deionized water.
The other components of the repair cream, soothing and repairing composition of this comparative example were the same as example 14, with 6.0% of the soothing and repairing composition.
Comparative example 6 (preparation of a repair cream containing 6.0% soothing repair composition)
The soothing and repairing composition used in the comparative example is prepared from the following components in parts by weight: humectant glycerin 4%, hydrolyzed lupin protein 4.5%, vegetarian flower extract 4.5%, preservative phenoxyethanol 1.5%, and the balance of deionized water.
The other components of the repair cream, soothing and repairing composition of this comparative example were the same as example 14, with 6.0% of the soothing and repairing composition.
And (3) evaluating the product effect:
in order to evaluate the soothing and repairing effects of different formula products, 120 normal skin groups were selected and randomly divided into A, B, C, D, E, F six groups, and capsicum oil stimulation repairing experiments were performed on two of 11 products (5 soothing and repairing products and 6 comparative products), respectively. Then 90 sensitive skin or conscious sensitive skin volunteers are selected, and are averagely and randomly divided into 3 groups, and the human trial effect evaluation is carried out on the formula products subjected to preliminary screening.
The specific test method of the capsicol stimulation repair experiment comprises the following steps: cleaning the left and right forearms of the volunteer in an environment with the temperature of 20-26 ℃ and the relative humidity of 50-60%, defining a square area (50mm × 50mm) on each of the left and right forearms, applying equal amount of chili oil in the area, stimulating the left and right forearms for 20min, washing with 45 deg.C hot water to remove chili oil, the different formulations were applied to the area where the capsicum oil was applied according to the divided cases and one area was reserved as a blank control area (no product was applied) (six groups of people trying the cases of products: A: example 11 and example 12; B: example 13 and example 14; C: example 15 and comparative example 1; D: comparative example 2 and comparative example 3; E: comparative example 4 and comparative example 5; F: comparative example 6 and blank), and the redness and swelling of the forearm were observed at intervals and the time for complete analgesia and the time for complete redness reduction were noted.
The specific method for evaluating the trial effect of the sensitive skin soothing and repairing human body comprises the following steps: after cleaning the skin in the morning and evening, a proper amount of the product is taken and applied to the face or the affected part for one month. Effect judgment standard: the effect is obvious: the subjective symptoms disappear entirely or mostly; the method has the following advantages: reduction of subjective symptoms or partial disappearance of symptoms; and (4) invalidation: no change, or no apparent change in subjective symptoms.
The results of the trial are shown in table 1 below:
TABLE 1 Chili oil stimulation repair experiment
From the above experimental results (example 14 and comparative examples 1-6), it can be seen that the effect of the three plant extracts is significantly better than that of the single extract and that of the two extracts, indicating that the three extracts have synergistic effect. When the composition is added in the same amount (examples 13 and 14), the repairing effect of the cream product is slightly better than that of the emulsion product, which is probably because the content of the oil in the cream product is higher, and the oil has certain moistening and nursing effects on the skin.
Three products (example 13, example 14 and example 15) with better effects are put into sensitive skin volunteers, and the results of the evaluation on the trial effect of the human body are shown in the following table 2:
TABLE 2 trial effect experiment on human body
As can be seen from the results of the capsicum oil stimulation repair experiment and the human body trial effect evaluation, the skin care product added with the soothing repair composition can effectively relieve the problems of skin pain, red swelling, pruritus and the like caused by skin stimulation or sensitivity, and can obviously improve the skin sensitivity. The higher the amount of the soothing repairing composition added, the more obvious the repairing effect.
The foregoing shows and describes the general principles and features of the present invention, together with the advantages thereof. It will be understood by those skilled in the art that the present invention is not limited to the embodiments described above, which are described in the specification and illustrated only to illustrate the principle of the present invention, but that various changes and modifications may be made therein without departing from the spirit and scope of the present invention, which fall within the scope of the invention as claimed. The scope of the invention is defined by the appended claims and equivalents thereof.
Claims (7)
1. A soothing and rejuvenating composition comprising a plurality of plant extracts, characterized by: the soothing and repairing composition is prepared from the following components in parts by weight: 1-10% of humectant, 3-10% of soothing and repairing agent, 0.1-5% of preservative and the balance of deionized water; the soothing and repairing agent is a composition of hydrolyzed lupin protein, carob fruit extract and vegetarian flower extract; the weight ratio of the hydrolyzed lupin protein to the carob seed extract to the vegetarian square flower extract is 1.0:2.0: 1.0.
2. A soothing repair composition according to claim 1, characterized in that: the preservative is one or more of phenoxyethanol, ethylhexyl glycerol, 1, 2-pentanediol and 1, 2-hexanediol.
3. A soothing repair composition according to claim 1, characterized in that: the humectant is one or more of 1, 3-propylene glycol, butanediol and glycerol.
4. A process for the preparation of a soothing and repairing composition according to any of claims 1 to 3, characterized by the following steps: heating the mixture of water and humectant to 90 deg.C, sterilizing for 30min, cooling to 45 deg.C, adding soothing and repairing agent and antiseptic in proportion, and stirring to obtain soothing and repairing composition containing multiple plant extracts.
5. Use of a soothing servicing composition according to any of claims 1 to 3, characterized in that: the soothing repair composition is used to prepare dosage forms including, but not limited to: soothing repair essence cream and soothing repair cream.
6. Use of a soothing servicing composition according to claim 5, characterized in that: the addition amount of the soothing and repairing composition is 2% -8%.
7. Use of a soothing servicing composition according to claim 5, characterized in that: the addition amount of the soothing and repairing composition is 4% -8%.
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| CN110215423A (en) * | 2019-06-19 | 2019-09-10 | 珠海远大美业生物科技有限公司 | The anti-ageing composition of reparation containing various plants extract, preparation method and application |
| CN112370392A (en) * | 2020-12-02 | 2021-02-19 | 上海珈凯生物科技有限公司 | Green tangerine peel-containing irritation relieving composition and preparation method thereof |
| CN112569139A (en) * | 2021-02-05 | 2021-03-30 | 东晟源研究院(广州)有限公司 | Soothing gel containing anti-inflammatory repairing composition and preparation method thereof |
| CN116672296B (en) * | 2023-08-01 | 2023-11-03 | 珠海远大美业生物科技有限公司 | Compound plant extract with soothing and repairing effects, and preparation method and application thereof |
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| CN102580054A (en) * | 2012-02-24 | 2012-07-18 | 北京章光101科技股份有限公司 | Female scalp soothing hair-care shampoo and preparation method thereof |
| CN106176555A (en) * | 2016-08-31 | 2016-12-07 | 广东芭薇生物科技股份有限公司 | For repairing pox print and the compositions of cicatrix and application thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102580054A (en) * | 2012-02-24 | 2012-07-18 | 北京章光101科技股份有限公司 | Female scalp soothing hair-care shampoo and preparation method thereof |
| CN106176555A (en) * | 2016-08-31 | 2016-12-07 | 广东芭薇生物科技股份有限公司 | For repairing pox print and the compositions of cicatrix and application thereof |
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