CN114848554A - Plant compound for preventing hair loss and growing hair and preparation method thereof - Google Patents

Plant compound for preventing hair loss and growing hair and preparation method thereof Download PDF

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CN114848554A
CN114848554A CN202210575529.0A CN202210575529A CN114848554A CN 114848554 A CN114848554 A CN 114848554A CN 202210575529 A CN202210575529 A CN 202210575529A CN 114848554 A CN114848554 A CN 114848554A
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CN114848554B (en
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于力
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Liu Wenyang
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Pinko Biotechnology Guangzhou Co ltd
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
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    • A61K8/9789Magnoliopsida [dicotyledons]
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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Abstract

The invention discloses a plant compound for preventing hair loss and growing hair and a preparation method thereof, belonging to the technical field of daily chemical products. The plant compound comprises the following raw materials in percentage by weight: astragalus root: 100-150 parts of glossy privet fruit: 80-120 parts of cacumen biotae: 60-80 parts of prepared rehmannia root: 40-70 parts of cortex dictamni: 30-60 parts of eclipta alba: 30-50 parts of camellia oil extract: 15-25 parts, licorice extract: 2-10 parts of konjak polypeptide extract: 1-5 parts, and the preparation comprises the following steps: grinding radix astragali, glossy privet fruit, cacumen biotae, prepared rehmannia root, cortex dictamni and eclipta alba into powder, wherein the particle size of the powder is 1000 meshes, and mixing the powder with deionized water, wherein the mass ratio of the powder to the deionized water is 1: 50, obtaining a serous fluid, and finally mixing the serous fluid with the camellia oil extract, the liquorice extract and the konjac polypeptide extract. Tests show that the hair-growing and hair-blackening cream has better effects of preventing hair loss, growing hair, blackening hair and the like.

Description

Plant compound for preventing hair loss and growing hair and preparation method thereof
Technical Field
The invention belongs to the technical field of daily chemical products, and particularly relates to a plant compound for preventing alopecia and growing hair and a preparation method thereof.
Background
After the middle-aged, the function of internal organs is reduced with the age, the metabolism surface is depressed, and the aging of the human body is promoted. With the development of economy, the pace of modern life is accelerated and the pressure of life is increased, because immune dysfunction and the cause of infection by the pathogenic factors such as infection or tea diseases cause the hair follicle and the hair mother cell to shrink, the hair diseases such as white hair, alopecia, halter and the like to have higher and higher morbidity, and the modern life is troubled more and more. Alopecia not only affects the beauty, but also causes bad emotions such as self-inferior, depression and the like to the psychology of patients, thereby affecting normal work, life and social activities. Alopecia can be classified into seborrheic alopecia, premature alopecia, alopecia areata, alopecia totalis, alopecia universalis, postpartum alopecia and the like according to symptoms, and no specific medicine can treat alopecia at present.
Traditional Chinese medicine considers that alopecia is mostly caused by physical dysfunction, and the pathogenesis of alopecia is caused by both mental and nutritional reasons. The melancholy can cause damage to the liver, the kidney, the heart and the spleen, and the hair loses nutrition and falls off; or alopecia due to deficiency of blood and insufficiency of blood supply to scalp and hair root.
However, the existing shampoo is generally prepared by mixing chemically synthesized substances at a later stage, has the functions of washing hair and preventing hair from being damaged after long-term use, and can damage hair follicles of users in serious cases; the existing people are stressed and stay up all night, the hair follicle health of the user is also influenced, the hair loss and hair loss of the user can occur after a long time, the mood of the user can be influenced after the hair loss and hair loss of the user, and the beauty lover is stricken greatly.
Disclosure of Invention
1. Problems to be solved
Aiming at the problems in the prior art, the invention provides the anti-hair loss and hair growth plant compound and the preparation method thereof, and the anti-hair loss and hair growth plant compound has better anti-hair loss, hair growth, hair blackening and other effects.
2. Technical scheme
In order to solve the above problems, the present invention adopts the following technical solutions.
A plant composition for preventing alopecia and promoting hair growth,
the composite material comprises the following raw materials in percentage by weight:
Figure BDA0003660407860000011
Figure BDA0003660407860000021
in the plant compound for preventing and growing the hair,
the composite material comprises the following raw materials in percentage by weight:
Figure BDA0003660407860000022
in the plant compound for preventing and growing hair described above,
the composite material comprises the following raw materials in percentage by weight:
Figure BDA0003660407860000023
in the plant compound for preventing and growing hair described above,
the astragalus root, the glossy privet fruit, the cacumen biotae, the prepared rehmannia root, the dittany bark and the eclipta alba are purchased from Chinese traditional medicine company Limited.
In the plant compound for preventing and growing hair described above,
the preparation method of the camellia oil extract comprises the following steps:
screening, cleaning and peeling camellia oil seeds, and drying at 85 ℃ for later use; crushing camellia oil seeds in a crusher to obtain crushed seed kernels; sending the crushed kernels into a hydraulic presser for pressing, wherein the pressing process parameters are as follows: feeding at 55 deg.C, squeezing at 60 deg.C under 12MPa for 20min for 3 times to obtain crude oil; and (4) delivering the mixture into a low-temperature centrifuge for high-speed centrifugation, wherein the rotating speed is 20000rpm, and taking the upper-layer grease.
In the plant compound for preventing and growing hair described above,
the preparation method of the licorice extract comprises the following steps:
drying liquorice, cutting into particles, mixing the particles with anhydrous acetone in a ratio of 1: 10, the mixing temperature is 65 ℃, standing extraction is carried out for 6 hours, centrifugation is carried out at 10000rpm for 10min, and supernate is collected and rotary evaporated to form the acetone anhydrous.
In the plant compound for preventing and growing hair described above,
the preparation method of the konjac polypeptide extract comprises the following steps:
cleaning and peeling konjak, crushing and stirring at low temperature, adding Tris-HCl buffer solution and neutral protease for ultrasonic-assisted dissolution, wherein the concentration of the Tris-HCl buffer solution is 0.8M, the pH value of the Tris-HCl buffer solution is 6.8-7.0, centrifuging, taking supernatant, and freeze-drying to obtain the konjak.
A preparation method of a plant compound for preventing hair loss and growing hair comprises the following steps:
grinding radix astragali, glossy privet fruit, cacumen biotae, prepared rehmannia root, cortex dictamni and eclipta alba into powder, wherein the particle size of the powder is 1000 meshes, and mixing the powder with deionized water, wherein the mass ratio of the powder to the deionized water is 1: 50, obtaining a serous fluid, and finally mixing the serous fluid with the camellia oil extract, the liquorice extract and the konjac polypeptide extract.
3. Advantageous effects
Compared with the prior art, the invention has the beneficial effects that:
the product designed by the application has a good hair loss prevention and hair growth effect, the hair density of the hair can reach 75.7% by using the product for six months, and the using amount is only 1 g/time. The three extracts (camellia oil extract, liquorice extract and konjac polypeptide extract) play a key role, and are mutually synergistic with other active substances to improve the blood circulation of the scalp, mainly increase and form the capillaries around the hair follicle, provide sufficient nutrition for the hair, improve the activity of the hair follicle, and simultaneously can improve the activity of hair papilla cells so as to prevent pore blockage caused by vigorous oil secretion, accelerate alopecia, and promote new hair growth by active ingredients permeating into the hair follicle. Therefore, the hair loss can be effectively prevented, the hair growth can be promoted, and the scalp allergy can not be caused. The preparation method is simple and convenient, and is convenient for large-scale production. Meanwhile, clinical experiments are carried out, after the hair conditioner is used for 7 days, the product prepared in the embodiment 5 of the invention has a good effect, after the product is continuously used for 15 days, the hair is gradually blackish and bright, soft and smooth, and after 1 month, dandruff, hair oil and head itch are greatly reduced, so that the hair is bright and glossy and is rich in elasticity.
Detailed Description
Example 1
The anti-hair loss and hair growth promoting plant compound comprises the following raw materials in percentage by weight:
Figure BDA0003660407860000041
in the plant compound for preventing and growing hair described above,
the astragalus root, the glossy privet fruit, the cacumen biotae, the prepared rehmannia root, the dittany bark and the eclipta alba are purchased from Chinese traditional medicine company Limited.
In the plant compound for preventing and growing hair described above,
the preparation method of the camellia oil extract comprises the following steps:
screening, cleaning and peeling camellia oil seeds, and drying at 85 ℃ for later use; crushing camellia oil seeds in a crusher to obtain crushed seed kernels; the crushed kernel is sent into a hydraulic presser for pressing, wherein the pressing technological parameters are as follows: feeding at 55 deg.C, squeezing at 60 deg.C under 12MPa for 20min for 3 times to obtain crude oil; and (4) delivering the mixture into a low-temperature centrifuge for high-speed centrifugation, wherein the rotating speed is 20000rpm, and taking the upper-layer grease.
In the plant compound for preventing and growing hair described above,
the preparation method of the licorice extract comprises the following steps:
drying liquorice, cutting into particles, mixing the particles with anhydrous acetone in a ratio of 1: 10, standing and extracting at the mixing temperature of 65 ℃ for 6h, centrifuging at low temperature of 10000rpm for 10min, collecting supernate, and rotationally evaporating anhydrous acetone to obtain the product.
In the plant compound for preventing and growing hair described above,
the preparation method of the konjac polypeptide extract comprises the following steps:
cleaning rhizoma Amorphophalli, peeling, crushing at low temperature, stirring, adding Tris-HCl buffer solution with concentration of 0.8M and neutral protease with pH of 6.8-7.0, and ultrasonically dissolving with-20 deg.C freeze-drying after centrifuging (5000 rpm).
The preparation method of the plant compound for preventing alopecia and growing hair comprises the following steps:
grinding radix astragali, glossy privet fruit, cacumen biotae, prepared rehmannia root, cortex dictamni and eclipta alba into powder, wherein the particle size of the powder is 1000 meshes, and mixing the powder with deionized water, wherein the mass ratio of the powder to the deionized water is 1: 50, obtaining a serous fluid, and finally mixing the serous fluid with the camellia oil extract, the liquorice extract and the konjac polypeptide extract, wherein the mixing temperature is 35 ℃.
Example 2
The anti-hair loss and hair growth promoting plant compound comprises the following raw materials in percentage by weight:
Figure BDA0003660407860000051
in the plant compound for preventing and growing hair described above,
the astragalus root, the glossy privet fruit, the cacumen biotae, the prepared rehmannia root, the dittany bark and the eclipta alba are purchased from Chinese traditional medicine company Limited.
In the plant compound for preventing and growing the hair,
the preparation method of the camellia oil extract comprises the following steps:
screening, cleaning and peeling camellia oil seeds, and drying at 85 ℃ for later use; crushing camellia oil seeds in a crusher to obtain crushed seed kernels; sending the crushed kernels into a hydraulic presser for pressing, wherein the pressing process parameters are as follows: feeding at 55 deg.C, barrel temperature of 60 deg.C, squeezing pressure of 12MPa, squeezing time of 20min, and squeezing times of 3 times to obtain crude oil; and (4) delivering the mixture into a low-temperature centrifuge for high-speed centrifugation, wherein the rotating speed is 20000rpm, and taking the upper-layer grease.
In the plant compound for preventing and growing hair described above,
the preparation method of the licorice extract comprises the following steps:
drying liquorice, cutting into particles, mixing the particles with anhydrous acetone in a ratio of 1: 10, the mixing temperature is 65 ℃, standing extraction is carried out for 6 hours, centrifugation is carried out at 10000rpm for 10min, and supernate is collected and rotary evaporated to form the acetone anhydrous.
In the plant compound for preventing and growing the hair,
the preparation method of the konjac polypeptide extract comprises the following steps:
cleaning rhizoma Amorphophalli, peeling, crushing at low temperature, stirring, adding Tris-HCl buffer solution with concentration of 0.8M and neutral protease with pH of 6.8-7.0, and ultrasonically dissolving with-20 deg.C freeze-drying after centrifuging (5000 rpm).
The preparation method of the plant compound for preventing alopecia and growing hair comprises the following steps:
grinding radix astragali, glossy privet fruit, cacumen biotae, prepared rehmannia root, cortex dictamni and eclipta alba into powder, wherein the particle size of the powder is 1000 meshes, and mixing the powder with deionized water, wherein the mass ratio of the powder to the deionized water is 1: 50, obtaining a serous fluid, and finally mixing the serous fluid with the camellia oil extract, the liquorice extract and the konjac polypeptide extract, wherein the mixing temperature is 35 ℃.
Example 3
The anti-hair loss and hair growth promoting plant compound comprises the following raw materials in percentage by weight:
Figure BDA0003660407860000061
in the plant compound for preventing and growing hair described above,
the astragalus root, the glossy privet fruit, the cacumen biotae, the prepared rehmannia root, the dittany bark and the eclipta alba are purchased from Chinese traditional medicine company Limited.
In the plant compound for preventing and growing hair described above,
the preparation method of the camellia oil extract comprises the following steps:
screening, cleaning and peeling camellia oil seeds, and drying at 85 ℃ for later use; crushing camellia oil seeds in a crusher to obtain crushed seed kernels; sending the crushed kernels into a hydraulic presser for pressing, wherein the pressing process parameters are as follows: feeding at 55 deg.C, squeezing at 60 deg.C under 12MPa for 20min for 3 times to obtain crude oil; and (4) delivering the mixture into a low-temperature centrifuge for high-speed centrifugation, wherein the rotating speed is 20000rpm, and taking the upper-layer grease.
In the plant compound for preventing and growing hair described above,
the preparation method of the licorice extract comprises the following steps:
drying liquorice, cutting into particles, mixing the particles with anhydrous acetone in a ratio of 1: 10, the mixing temperature is 65 ℃, standing extraction is carried out for 6 hours, centrifugation is carried out at 10000rpm for 10min, and supernate is collected and rotary evaporated to form the acetone anhydrous.
In the plant compound for preventing and growing hair described above,
the preparation method of the konjac polypeptide extract comprises the following steps:
cleaning rhizoma Amorphophalli, peeling, crushing at low temperature, stirring, adding Tris-HCl buffer solution with concentration of 0.8M and neutral protease with pH of 6.8-7.0, and ultrasonically dissolving with-20 deg.C freeze-drying after centrifuging (5000 rpm).
The preparation method of the plant compound for preventing alopecia and growing hair comprises the following steps:
grinding radix astragali, glossy privet fruit, cacumen biotae, prepared rehmannia root, cortex dictamni and eclipta alba into powder, wherein the particle size of the powder is 1000 meshes, and mixing the powder with deionized water, wherein the mass ratio of the powder to the deionized water is 1: 50, obtaining a serous fluid, and finally mixing the serous fluid with the camellia oil extract, the liquorice extract and the konjac polypeptide extract, wherein the mixing temperature is 35 ℃.
Example 4
The anti-hair loss and hair growth promoting plant compound comprises the following raw materials in percentage by weight:
Figure BDA0003660407860000071
in the plant compound for preventing and growing hair described above,
the astragalus root, the glossy privet fruit, the cacumen biotae, the prepared rehmannia root, the dittany bark and the eclipta alba are purchased from Chinese traditional medicine company Limited.
In the plant compound for preventing and growing hair described above,
the preparation method of the camellia oil extract comprises the following steps:
screening, cleaning and peeling camellia oil seeds, and drying at 85 ℃ for later use; crushing camellia oil seeds in a crusher to obtain crushed seed kernels; sending the crushed kernels into a hydraulic presser for pressing, wherein the pressing process parameters are as follows: feeding at 55 deg.C, squeezing at 60 deg.C under 12MPa for 20min for 3 times to obtain crude oil; and (4) delivering the mixture into a low-temperature centrifuge for high-speed centrifugation, wherein the rotating speed is 20000rpm, and taking the upper-layer grease.
In the plant compound for preventing and growing hair described above,
the preparation method of the licorice extract comprises the following steps:
drying liquorice in the sun, cutting into particles, mixing the particles with anhydrous acetone in a proportion of 1: 10, the mixing temperature is 65 ℃, standing extraction is carried out for 6 hours, centrifugation is carried out at 10000rpm for 10min, and supernate is collected and rotary evaporated to form the acetone anhydrous.
In the plant compound for preventing and growing hair described above,
the preparation method of the konjac polypeptide extract comprises the following steps:
cleaning rhizoma Amorphophalli, peeling, crushing at low temperature, stirring, adding Tris-HCl buffer solution with concentration of 0.8M and neutral protease with pH of 6.8-7.0, ultrasonically dissolving, centrifuging (5000rpm), collecting supernatant, and freeze drying at-20 deg.C.
The preparation method of the plant compound for preventing alopecia and growing hair comprises the following steps:
grinding radix astragali, glossy privet fruit, cacumen biotae, prepared rehmannia root, cortex dictamni and eclipta alba into powder, wherein the particle size of the powder is 1000 meshes, and mixing the powder with deionized water, wherein the mass ratio of the powder to the deionized water is 1: 50, obtaining a serous fluid, and finally mixing the serous fluid with the camellia oil extract, the liquorice extract and the konjac polypeptide extract, wherein the mixing temperature is 35 ℃.
Example 5
The anti-hair loss and hair growth promoting plant compound comprises the following raw materials in percentage by weight:
Figure BDA0003660407860000081
in the plant compound for preventing and growing the hair,
the astragalus root, the glossy privet fruit, the cacumen biotae, the prepared rehmannia root, the dittany bark and the eclipta alba are purchased from Chinese traditional medicine company Limited.
In the plant compound for preventing and growing hair described above,
the preparation method of the camellia oil extract comprises the following steps:
screening, cleaning and peeling camellia oil seeds, and drying at 85 ℃ for later use; crushing camellia oil seeds in a crusher to obtain crushed seed kernels; sending the crushed kernels into a hydraulic presser for pressing, wherein the pressing process parameters are as follows: feeding at 55 deg.C, squeezing at 60 deg.C under 12MPa for 20min for 3 times to obtain crude oil; and (4) delivering the mixture into a low-temperature centrifuge for high-speed centrifugation, wherein the rotating speed is 20000rpm, and taking the upper-layer grease.
In the plant compound for preventing and growing hair described above,
the preparation method of the licorice extract comprises the following steps:
drying liquorice, cutting into particles, mixing the particles with anhydrous acetone in a ratio of 1: 10, the mixing temperature is 65 ℃, standing extraction is carried out for 6 hours, centrifugation is carried out at 10000rpm for 10min, and supernate is collected and rotary evaporated to form the acetone anhydrous.
In the plant compound for preventing and growing hair described above,
the preparation method of the konjac polypeptide extract comprises the following steps:
cleaning rhizoma Amorphophalli, peeling, crushing at low temperature, stirring, adding Tris-HCl buffer solution with concentration of 0.8M and neutral protease with pH of 6.8-7.0, and ultrasonically dissolving with-20 deg.C freeze-drying after centrifuging (5000 rpm).
The preparation method of the plant compound for preventing alopecia and growing hair comprises the following steps:
grinding radix astragali, glossy privet fruit, cacumen biotae, prepared rehmannia root, cortex dictamni and eclipta alba into powder, wherein the particle size of the powder is 1000 meshes, and mixing the powder with deionized water, wherein the mass ratio of the powder to the deionized water is 1: 50, obtaining a serous fluid, and finally mixing the serous fluid with the camellia oil extract, the liquorice extract and the konjac polypeptide extract, wherein the mixing temperature is 35 ℃.
Comparative example 1
The anti-hair loss and hair growth promoting plant compound comprises the following raw materials in percentage by weight:
Figure BDA0003660407860000091
in the plant compound for preventing and growing hair described above,
the astragalus root, the glossy privet fruit, the cacumen biotae, the prepared rehmannia root, the dittany bark and the eclipta alba are purchased from Chinese traditional medicine company Limited.
In the plant compound for preventing and growing hair described above,
the preparation method of the licorice extract comprises the following steps:
drying liquorice, cutting into particles, mixing the particles with anhydrous acetone in a ratio of 1: 10, the mixing temperature is 65 ℃, standing extraction is carried out for 6 hours, centrifugation is carried out at 10000rpm for 10min, and supernate is collected and rotary evaporated to form the acetone anhydrous.
In the plant compound for preventing and growing hair described above,
the preparation method of the konjac polypeptide extract comprises the following steps:
cleaning rhizoma Amorphophalli, peeling, crushing at low temperature, stirring, adding Tris-HCl buffer solution with concentration of 0.8M and neutral protease with pH of 6.8-7.0, and ultrasonically dissolving with-20 deg.C freeze-drying after centrifuging (5000 rpm).
The preparation method of the plant compound for preventing alopecia and growing hair comprises the following steps:
grinding radix astragali, glossy privet fruit, cacumen biotae, prepared rehmannia root, cortex dictamni and eclipta alba into powder, wherein the particle size of the powder is 1000 meshes, and mixing the powder with deionized water, wherein the mass ratio of the powder to the deionized water is 1: 50, obtaining a serous fluid, and finally mixing the serous fluid with the liquorice extract and the konjak polypeptide extract, wherein the mixing temperature is 35 ℃.
Comparative example 2
The anti-hair loss and hair growth promoting plant compound comprises the following raw materials in percentage by weight:
Figure BDA0003660407860000101
in the plant compound for preventing and growing hair described above,
the astragalus root, the glossy privet fruit, the cacumen biotae, the prepared rehmannia root, the dittany bark and the eclipta alba are purchased from Chinese traditional medicine company Limited.
In the plant compound for preventing and growing hair described above,
the preparation method of the camellia oil extract comprises the following steps:
screening, cleaning and peeling camellia oil seeds, and drying at 85 ℃ for later use; crushing camellia oil seeds in a crusher to obtain crushed seed kernels; sending the crushed kernels into a hydraulic presser for pressing, wherein the pressing process parameters are as follows: feeding at 55 deg.C, barrel temperature of 60 deg.C, squeezing pressure of 12MPa, squeezing time of 20min, and squeezing times of 3 times to obtain crude oil; and (4) delivering the mixture into a low-temperature centrifuge for high-speed centrifugation, wherein the rotating speed is 20000rpm, and taking the upper-layer grease.
In the plant compound for preventing and growing hair described above,
the preparation method of the konjac polypeptide extract comprises the following steps:
cleaning rhizoma Amorphophalli, peeling, crushing at low temperature, stirring, adding Tris-HCl buffer solution with concentration of 0.8M and neutral protease with pH of 6.8-7.0, ultrasonically dissolving, centrifuging (5000rpm), collecting supernatant, and freeze drying at-20 deg.C.
The preparation method of the plant compound for preventing alopecia and growing hair comprises the following steps:
grinding radix astragali, glossy privet fruit, cacumen biotae, prepared rehmannia root, cortex dictamni and eclipta alba into powder, wherein the particle size of the powder is 1000 meshes, and mixing the powder with deionized water, wherein the mass ratio of the powder to the deionized water is 1: 50, obtaining a serous fluid, and finally mixing the serous fluid with the camellia oil extract and the konjac polypeptide extract, wherein the mixing temperature is 35 ℃.
Comparative example 3
The anti-hair loss and hair growth promoting plant compound comprises the following raw materials in percentage by weight:
Figure BDA0003660407860000111
in the plant compound for preventing and growing hair described above,
the astragalus root, the glossy privet fruit, the cacumen biotae, the prepared rehmannia root, the dittany bark and the eclipta alba are purchased from Chinese traditional medicine company Limited.
In the plant compound for preventing and growing hair described above,
the preparation method of the camellia oil extract comprises the following steps:
screening, cleaning and peeling camellia oil seeds, and drying at 85 ℃ for later use; crushing camellia oil seeds in a crusher to obtain crushed seed kernels; sending the crushed kernels into a hydraulic presser for pressing, wherein the pressing process parameters are as follows: feeding at 55 deg.C, squeezing at 60 deg.C under 12MPa for 20min for 3 times to obtain crude oil; and (4) delivering the mixture into a low-temperature centrifugal machine for high-speed centrifugation, wherein the rotating speed is 20000rpm, and taking the upper-layer grease to obtain the high-temperature-resistant and high-speed-resistant grease.
In the plant compound for preventing and growing hair described above,
the preparation method of the licorice extract comprises the following steps:
drying liquorice, cutting into particles, mixing the particles with anhydrous acetone in a ratio of 1: 10, the mixing temperature is 65 ℃, standing extraction is carried out for 6 hours, centrifugation is carried out at 10000rpm for 10min, and supernate is collected and rotary evaporated to form the acetone anhydrous.
The preparation method of the plant compound for preventing alopecia and growing hair comprises the following steps:
grinding radix astragali, glossy privet fruit, cacumen biotae, prepared rehmannia root, cortex dictamni and eclipta alba into powder, wherein the particle size of the powder is 1000 meshes, and mixing the powder with deionized water, wherein the mass ratio of the powder to the deionized water is 1: 50, obtaining a serous fluid, and finally mixing the serous fluid with the camellia oil extract and the liquorice extract, wherein the mixing temperature is 35 ℃.
Comparative example 4
The anti-hair loss and hair growth promoting plant compound comprises the following raw materials in percentage by weight:
Figure BDA0003660407860000121
in the plant compound for preventing and growing hair described above,
the astragalus root, the prepared rehmannia root, the cortex dictamni and the eclipta alba are purchased from Chinese traditional medicine company Limited.
In the plant compound for preventing and growing hair described above,
the preparation method of the camellia oil extract comprises the following steps:
screening, cleaning and peeling camellia oil seeds, and drying at 85 ℃ for later use; crushing camellia oil seeds in a crusher to obtain crushed seed kernels; sending the crushed kernels into a hydraulic presser for pressing, wherein the pressing process parameters are as follows: feeding at 55 deg.C, barrel temperature of 60 deg.C, squeezing pressure of 12MPa, squeezing time of 20min, and squeezing times of 3 times to obtain crude oil; and (4) delivering the mixture into a low-temperature centrifuge for high-speed centrifugation, wherein the rotating speed is 20000rpm, and taking the upper-layer grease.
In the plant compound for preventing and growing the hair,
the preparation method of the licorice extract comprises the following steps:
drying liquorice, cutting into particles, mixing the particles with anhydrous acetone in a ratio of 1: 10, the mixing temperature is 65 ℃, standing extraction is carried out for 6 hours, centrifugation is carried out at 10000rpm for 10min, and supernate is collected and rotary evaporated to form the acetone anhydrous.
In the plant compound for preventing and growing hair described above,
the preparation method of the konjac polypeptide extract comprises the following steps:
cleaning rhizoma Amorphophalli, peeling, crushing at low temperature, stirring, adding Tris-HCl buffer solution with concentration of 0.8M and neutral protease with pH of 6.8-7.0, and ultrasonically dissolving with-20 deg.C freeze-drying after centrifuging (5000 rpm).
The preparation method of the plant compound for preventing hair loss and growing hair comprises the following steps:
grinding radix astragali, radix rehmanniae Preparata, cortex Dictamni Radicis and Ecliptae herba into powder, wherein the particle size of the powder is 1000 meshes, and mixing the powder with deionized water, wherein the mass ratio of the powder to the deionized water is 1: 50, obtaining a serous fluid, and finally mixing the serous fluid with the camellia oil extract, the liquorice extract and the konjac polypeptide extract, wherein the mixing temperature is 35 ℃.
Comparative example 5
The anti-hair loss and hair growth promoting plant compound comprises the following raw materials in percentage by weight:
Figure BDA0003660407860000131
in the plant compound for preventing and growing hair described above,
the astragalus root, the glossy privet fruit, the cacumen biotae and the eclipta alba are purchased from Chinese traditional medicine limited company.
In the plant compound for preventing and growing hair described above,
the preparation method of the camellia oil extract comprises the following steps:
screening, cleaning and peeling camellia oil seeds, and drying at 85 ℃ for later use; crushing camellia oil seeds in a crusher to obtain crushed seed kernels; sending the crushed kernels into a hydraulic presser for pressing, wherein the pressing process parameters are as follows: feeding at 55 deg.C, squeezing at 60 deg.C under 12MPa for 20min for 3 times to obtain crude oil; and (4) delivering the mixture into a low-temperature centrifuge for high-speed centrifugation, wherein the rotating speed is 20000rpm, and taking the upper-layer grease.
In the plant compound for preventing and growing hair described above,
the preparation method of the licorice extract comprises the following steps:
drying liquorice, cutting into particles, mixing the particles with anhydrous acetone in a ratio of 1: 10, the mixing temperature is 65 ℃, standing extraction is carried out for 6 hours, centrifugation is carried out at 10000rpm for 10min, and supernate is collected and rotary evaporated to form the acetone anhydrous.
In the plant compound for preventing and growing hair described above,
the preparation method of the konjac polypeptide extract comprises the following steps:
cleaning rhizoma Amorphophalli, peeling, crushing at low temperature, stirring, adding Tris-HCl buffer solution with concentration of 0.8M and neutral protease with pH of 6.8-7.0, and ultrasonically dissolving with-20 deg.C freeze-drying after centrifuging (5000 rpm).
The preparation method of the plant compound for preventing hair loss and growing hair comprises the following steps:
grinding radix astragali, fructus ligustri lucidi, cacumen biotae and herba ecliptae into powder, mixing the powder and deionized water, wherein the mass ratio of the powder to the deionized water is 1: 50, obtaining a serous fluid, and finally mixing the serous fluid with the camellia oil extract, the liquorice extract and the konjac polypeptide extract, wherein the mixing temperature is 35 ℃.
The test scheme is as follows:
200 alopecia areata groups of 30-55 years of age are selected, wherein 120 male people and 80 female people are selected. Trial objects with similar symptoms are distributed into each group as evenly as possible, and the proportion of male and female is distributed as evenly as possible.
(1) Alopecia preventing and hair growing ability
Before trial, the hair growth condition of a user (20 persons in each group on average and the hair density is close) is photographed, then the hair growth condition of the user is photographed by a camera every month, and finally the average value of each group is taken. The test method comprises the following steps: it is administered 1 g/time in the morning and evening each day. During the test period, subjects were protected from excessive uv exposure, and during the test period, products other than the test samples, etc. were not used for 180 days.
Table 1 hair Density test results
Figure BDA0003660407860000141
Figure BDA0003660407860000151
As seen from Table 1, the products prepared in examples 1 to 5 designed in this application have superior alopecia preventing and hair growing effects compared to those of comparative examples 1 to 5, and the hair density of the hair can be as high as 75.7% by six months of use, and the amount of use is only 1 g/time. The three extracts (camellia oil extract, liquorice extract and konjac polypeptide extract) play a key role, and are mutually synergistic with other active substances to improve the blood circulation of the scalp, mainly increase and form the capillaries around the hair follicle, provide sufficient nutrition for the hair, improve the activity of the hair follicle, and simultaneously can improve the activity of hair papilla cells so as to prevent pore blockage caused by vigorous oil secretion, accelerate alopecia, and promote new hair growth by active ingredients permeating into the hair follicle. Therefore, the hair loss can be effectively prevented, the hair growth can be promoted, and the scalp allergy can not be caused. The preparation method is simple and convenient, and is convenient for large-scale production.
(2) Ability to blacken hair
Example 5, which is the best to prevent hair loss, was tested as follows:
the using method comprises the following steps: cleaning hair, uniformly smearing 5g of product from hair tail to hair root, gently massaging until hair root, standing for 5min, wrapping hair with bath cap or hot towel, standing for 20min, and washing with warm water. It is used 1 time every 3 days.
Clinical experiments are carried out, the product prepared in the embodiment 5 of the invention has good effect after being used for 7 days, the hair quality is gradually blackish and bright and soft and smooth after being continuously used for 15 days, and scurf, hair oil and head itch are greatly reduced after 1 month, and the hair quality is bright, glossy and rich in elasticity.
While the invention has been described in further detail with reference to specific embodiments thereof, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (8)

1. A plant compound for preventing hair loss and growing hair is characterized in that:
the composite material comprises the following raw materials in percentage by weight:
Figure FDA0003660407850000011
2. the anti-alopecia, hair-growing plant compound according to claim 1, wherein:
the composite material comprises the following raw materials in percentage by weight:
Figure FDA0003660407850000012
3. the anti-alopecia, hair-growing plant compound according to claim 1, wherein:
the composite material comprises the following raw materials in percentage by weight:
Figure FDA0003660407850000013
Figure FDA0003660407850000021
4. the anti-alopecia, hair-growing plant compound of claim 1, wherein:
the astragalus root, the glossy privet fruit, the cacumen biotae, the prepared rehmannia root, the dittany bark and the eclipta alba are purchased from Chinese traditional medicine company Limited.
5. The anti-alopecia, hair-growing plant compound according to claim 1, wherein:
the preparation method of the camellia oil extract comprises the following steps:
screening, cleaning and peeling camellia oil seeds, and drying at 85 ℃ for later use; crushing camellia oil seeds in a crusher to obtain crushed seed kernels; sending the crushed kernels into a hydraulic presser for pressing, wherein the pressing process parameters are as follows: feeding at 55 deg.C, squeezing at 60 deg.C under 12MPa for 20min for 3 times to obtain crude oil; and (4) delivering the mixture into a low-temperature centrifuge for high-speed centrifugation, wherein the rotating speed is 20000rpm, and taking the upper-layer grease.
6. The anti-alopecia, hair-growing plant compound of claim 1, wherein:
the preparation method of the licorice extract comprises the following steps:
drying liquorice, cutting into particles, mixing the particles with anhydrous acetone in a ratio of 1: 10, the mixing temperature is 65 ℃, standing extraction is carried out for 6 hours, centrifugation is carried out at 10000rpm for 10min, and supernate is collected and rotary evaporated to form the acetone anhydrous.
7. The anti-alopecia, hair-growing plant compound according to claim 1, wherein:
the preparation method of the konjac polypeptide extract comprises the following steps:
cleaning and peeling konjak, crushing and stirring at low temperature, adding Tris-HCl buffer solution and neutral protease for ultrasonic-assisted dissolution, wherein the concentration of the Tris-HCl buffer solution is 0.8M, the pH value of the Tris-HCl buffer solution is 6.8-7.0, centrifuging, taking supernatant, and freeze-drying to obtain the konjak.
8. A preparation method of a plant compound for preventing hair loss and growing hair is characterized in that:
the method comprises the following steps:
grinding radix astragali, glossy privet fruit, cacumen biotae, prepared rehmannia root, cortex dictamni and eclipta alba into powder, wherein the particle size of the powder is 1000 meshes, and mixing the powder with deionized water, wherein the mass ratio of the powder to the deionized water is 1: 50, obtaining a serous fluid, and finally mixing the serous fluid with the camellia oil extract, the liquorice extract and the konjac polypeptide extract.
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